1C24A

E. coli methionine aminopeptidase: methionine phosphinate complex
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
pubmed doi rcsb
molecule keywords METHIONINE AMINOPEPTIDASE
molecule tags Hydrolase
source organism Escherichia coli
total genus 88
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1999-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1c24A00
1YW7A 2GU5A 4R60A 4IKUA 1R5HA 2NQ7A 1WKMA 1B59A 2GZ5A 4U76A 3PKEA 2BWYA 4KM3A 2BWXA 5CDVA 2BWWA 3BIPA 2B3KA 2GG5A 1C27A 3CB5A 3PKDA 2GU4A 4PNCA 2GG3A 2EVMA 3FMQA 5D6EA 2MATA 2GG8A 2V3YA 2BH3A 1O0XA 1QXWA 2B3LA 1XGOA 4A6WA 1QXZA 4IKTA 4RGZ1 1C22A 5CNXA 4OOKA 4IECA 5CDEA 4ZWPA 2P99A 2V6CA 4S01A 2Q92A 4FLJA 2GU6A 1WBQA 1R58A 2ADUA 5JHUA 4IU6A 1R5GA 1QXYA 2Q93A 2P98A 4FUKA 5E5BA 3PKCA 5FCFA 1WL9A 4U71A 1YW9A 3CB6A 4U73A 5D6FA 3IU7A 4U1BA 2Q95A 4U6CA 1JAWA 2BB7A 2BWTA 2OAZA 2NQ6A 4FKCA 2GU7A 5CLSA 4B28A 4FLLA 2GA2A 3Q6DA 3RVAA 2GG2A 2Q96A 4U6WA 2G6PA 2EA4A 1WL6A 2B3HA 1PV9A 4FLKA 3FM3A 1XGMA 1KQ0A 4S2TP 4QR8A 2EVOA 2GGBA 2DFIA 4MATA 2GG9A 5CIKA 2Q94A 2BHBA 4FLIA 4U6ZA 3IU8A 1W7VA 3BIQA 2ZSGA 2BHDA 3D27A 3MR1A 3PKAA 4FO7A 1XGSA 4ZWOA 3TB5A 2OKNA 4JUQA 2EVCA 1WLRA 1MATA 4Z7MA 4RZZA 2GTXA 1W2MA 1CHMA 4PV4A 3L24A 4U6EA 2BHCA 5JI6A 2BHAA 1YJ3A 1WN1A 2EA2A 4IKSA 2HOWA 2BWUA 1B6AA 3CTZA 1XNZA 1KQ9A 1BN5A 4HXXA 4IDYA 4IKRA 1BOAA 1C23A 1KP0A 4U69A 5JFRA 3MATA 4S2RP 4ZNGA 4U70A 3IG4A 2P9AA 4S00A 2IW2A 4IF7A 5FCHA 1Y1NA 4RZYA 2GG7A 2V3ZA 3RORA 2GGCA 3PKBA 4ZWUA 2V3XA 3S6BA 3TAVA 5CDLA 1A16A 1XGNA 4EGEA 4FO8A 4U75A 1N51A 3L7GA 1WY2A 3FMRA 3IU9A 3MX6A 2BWSA 3BITA 5CE6A 4IPAA 2BWVA 1C21A 1QZYA 4A6VA 1M35A 1YW8A 2Q8KA 4U6JA 1C24A 2BN7A 2GG0A 1YVMA
chains in the Genus database with same CATH superfamily
1YW7A 2GU5A 4R60A 4IKUA 1R5HA 2NQ7A 1WKMA 1B59A 2GZ5A 4U76A 3PKEA 2BWYA 4KM3A 2BWXA 5CDVA 2BWWA 3BIPA 2B3KA 2GG5A 1C27A 3CB5A 3PKDA 2GU4A 4PNCA 2GG3A 2EVMA 3FMQA 5D6EA 2MATA 2GG8A 2V3YA 2BH3A 1O0XA 1QXWA 2B3LA 1XGOA 4A6WA 1QXZA 4IKTA 4RGZ1 1C22A 5CNXA 4OOKA 4IECA 5CDEA 4ZWPA 2P99A 2V6CA 4S01A 2Q92A 4FLJA 2GU6A 1WBQA 1R58A 2ADUA 5JHUA 4IU6A 1R5GA 1QXYA 2Q93A 2P98A 4FUKA 5E5BA 3PKCA 5FCFA 1WL9A 4U71A 1YW9A 3CB6A 4U73A 5D6FA 3IU7A 4U1BA 2Q95A 4U6CA 1JAWA 2BB7A 2BWTA 2OAZA 2NQ6A 4FKCA 2GU7A 5CLSA 4B28A 4FLLA 2GA2A 3Q6DA 3RVAA 2GG2A 2Q96A 4U6WA 2G6PA 2EA4A 1WL6A 2B3HA 1PV9A 4FLKA 3FM3A 1XGMA 1KQ0A 4S2TP 4QR8A 2EVOA 2GGBA 2DFIA 4MATA 2GG9A 5CIKA 2Q94A 2BHBA 4FLIA 4U6ZA 3IU8A 1W7VA 3BIQA 2ZSGA 2BHDA 3D27A 3MR1A 3PKAA 4FO7A 1XGSA 4ZWOA 3TB5A 2OKNA 4JUQA 2EVCA 1WLRA 1MATA 4Z7MA 4RZZA 2GTXA 1W2MA 1CHMA 4PV4A 3L24A 4U6EA 2BHCA 5JI6A 2BHAA 1YJ3A 1WN1A 2EA2A 4IKSA 2HOWA 2BWUA 1B6AA 3CTZA 1XNZA 1KQ9A 1BN5A 4HXXA 4IDYA 4IKRA 1BOAA 1C23A 1KP0A 4U69A 5JFRA 3MATA 4S2RP 4ZNGA 4U70A 3IG4A 2P9AA 4S00A 2IW2A 4IF7A 5FCHA 1Y1NA 4RZYA 2GG7A 2V3ZA 3RORA 2GGCA 3PKBA 4ZWUA 2V3XA 3S6BA 3TAVA 5CDLA 1A16A 1XGNA 4EGEA 4FO8A 4U75A 1N51A 3L7GA 1WY2A 3FMRA 3IU9A 3MX6A 2BWSA 3BITA 5CE6A 4IPAA 2BWVA 1C21A 1QZYA 4A6VA 1M35A 1YW8A 2Q8KA 4U6JA 1C24A 2BN7A 2GG0A 1YVMA
chains in the Genus database with same CATH topology
1YW7A 2GU5A 4R60A 4IKUA 1R5HA 2NQ7A 1WKMA 1B59A 2GZ5A 4U76A 3PKEA 2BWYA 4KM3A 2BWXA 5CDVA 2BWWA 3BIPA 2B3KA 2GG5A 1C27A 3CB5A 3PKDA 2GU4A 4PNCA 2GG3A 2EVMA 3FMQA 5D6EA 2MATA 2GG8A 2V3YA 2BH3A 1O0XA 1QXWA 2B3LA 1XGOA 4A6WA 1QXZA 4IKTA 4RGZ1 1C22A 5CNXA 4OOKA 4IECA 5CDEA 4ZWPA 2P99A 2V6CA 4S01A 2Q92A 4FLJA 2GU6A 1WBQA 1R58A 2ADUA 5JHUA 4IU6A 1R5GA 1QXYA 2Q93A 2P98A 4FUKA 5E5BA 3PKCA 5FCFA 1WL9A 4U71A 1YW9A 3CB6A 4U73A 5D6FA 3IU7A 4U1BA 2Q95A 4U6CA 1JAWA 2BB7A 2BWTA 2OAZA 2NQ6A 4FKCA 2GU7A 5CLSA 4B28A 4FLLA 2GA2A 3Q6DA 3RVAA 2GG2A 2Q96A 4U6WA 2G6PA 2EA4A 1WL6A 2B3HA 1PV9A 4FLKA 3FM3A 1XGMA 1KQ0A 4S2TP 4QR8A 2EVOA 2GGBA 2DFIA 4MATA 2GG9A 5CIKA 2Q94A 2BHBA 4FLIA 4U6ZA 3IU8A 1W7VA 3BIQA 2ZSGA 2BHDA 3D27A 3MR1A 3PKAA 4FO7A 1XGSA 4ZWOA 3TB5A 2OKNA 4JUQA 2EVCA 1WLRA 1MATA 4Z7MA 4RZZA 2GTXA 1W2MA 1CHMA 4PV4A 3L24A 4U6EA 2BHCA 5JI6A 2BHAA 1YJ3A 1WN1A 2EA2A 4IKSA 2HOWA 2BWUA 1B6AA 3CTZA 1XNZA 1KQ9A 1BN5A 4HXXA 4IDYA 4IKRA 1BOAA 1C23A 1KP0A 4U69A 5JFRA 3MATA 4S2RP 4ZNGA 4U70A 3IG4A 2P9AA 4S00A 2IW2A 4IF7A 5FCHA 1Y1NA 4RZYA 2GG7A 2V3ZA 3RORA 2GGCA 3PKBA 4ZWUA 2V3XA 3S6BA 3TAVA 5CDLA 1A16A 1XGNA 4EGEA 4FO8A 4U75A 1N51A 3L7GA 1WY2A 3FMRA 3IU9A 3MX6A 2BWSA 3BITA 5CE6A 4IPAA 2BWVA 1C21A 1QZYA 4A6VA 1M35A 1YW8A 2Q8KA 4U6JA 1C24A 2BN7A 2GG0A 1YVMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YW7 A;  2GU5 A;  4R60 A;  4IKU A;  1R5H A;  2NQ7 A;  1WKM A;  1B59 A;  2GZ5 A;  4U76 A;  3PKE A;  2BWY A;  4KM3 A;  2BWX A;  5CDV A;  2BWW A;  3BIP A;  2B3K A;  2GG5 A;  1C27 A;  3CB5 A;  3PKD A;  2GU4 A;  4PNC A;  2GG3 A;  2EVM A;  3FMQ A;  5D6E A;  2MAT A;  2GG8 A;  2V3Y A;  2BH3 A;  1O0X A;  1QXW A;  2B3L A;  1XGO A;  4A6W A;  1QXZ A;  4IKT A;  4RGZ 1;  1C22 A;  5CNX A;  4OOK A;  4IEC A;  5CDE A;  4ZWP A;  2P99 A;  2V6C A;  4S01 A;  2Q92 A;  4FLJ A;  2GU6 A;  1WBQ A;  1R58 A;  2ADU A;  5JHU A;  4IU6 A;  1R5G A;  1QXY A;  2Q93 A;  2P98 A;  4FUK A;  5E5B A;  3PKC A;  5FCF A;  1WL9 A;  4U71 A;  1YW9 A;  3CB6 A;  4U73 A;  5D6F A;  3IU7 A;  4U1B A;  2Q95 A;  4U6C A;  1JAW A;  2BB7 A;  2BWT A;  2OAZ A;  2NQ6 A;  4FKC A;  2GU7 A;  5CLS A;  4B28 A;  4FLL A;  2GA2 A;  3Q6D A;  3RVA A;  2GG2 A;  2Q96 A;  4U6W A;  2G6P A;  2EA4 A;  1WL6 A;  2B3H A;  1PV9 A;  4FLK A;  3FM3 A;  1XGM A;  1KQ0 A;  4S2T P;  4QR8 A;  2EVO A;  2GGB A;  2DFI A;  4MAT A;  2GG9 A;  5CIK A;  2Q94 A;  2BHB A;  4FLI A;  4U6Z A;  3IU8 A;  1W7V A;  3BIQ A;  2ZSG A;  2BHD A;  3D27 A;  3MR1 A;  3PKA A;  4FO7 A;  1XGS A;  4ZWO A;  3TB5 A;  2OKN A;  4JUQ A;  2EVC A;  1WLR A;  1MAT A;  4Z7M A;  4RZZ A;  2GTX A;  1W2M A;  1CHM A;  4PV4 A;  3L24 A;  4U6E A;  2BHC A;  5JI6 A;  2BHA A;  1YJ3 A;  1WN1 A;  2EA2 A;  4IKS A;  2HOW A;  2BWU A;  1B6A A;  3CTZ A;  1XNZ A;  1KQ9 A;  1BN5 A;  4HXX A;  4IDY A;  4IKR A;  1BOA A;  1C23 A;  1KP0 A;  4U69 A;  5JFR A;  3MAT A;  4S2R P;  4ZNG A;  4U70 A;  3IG4 A;  2P9A A;  4S00 A;  2IW2 A;  4IF7 A;  5FCH A;  1Y1N A;  4RZY A;  2GG7 A;  2V3Z A;  3ROR A;  2GGC A;  3PKB A;  4ZWU A;  2V3X A;  3S6B A;  3TAV A;  5CDL A;  1A16 A;  1XGN A;  4EGE A;  4FO8 A;  4U75 A;  1N51 A;  3L7G A;  1WY2 A;  3FMR A;  3IU9 A;  3MX6 A;  2BWS A;  3BIT A;  5CE6 A;  4IPA A;  2BWV A;  1C21 A;  1QZY A;  4A6V A;  1M35 A;  1YW8 A;  2Q8K A;  4U6J A;  1C24 A;  2BN7 A;  2GG0 A;  1YVM A; 
#chains in the Genus database with same CATH topology
 1YW7 A;  2GU5 A;  4R60 A;  4IKU A;  1R5H A;  2NQ7 A;  1WKM A;  1B59 A;  2GZ5 A;  4U76 A;  3PKE A;  2BWY A;  4KM3 A;  2BWX A;  5CDV A;  2BWW A;  3BIP A;  2B3K A;  2GG5 A;  1C27 A;  3CB5 A;  3PKD A;  2GU4 A;  4PNC A;  2GG3 A;  2EVM A;  3FMQ A;  5D6E A;  2MAT A;  2GG8 A;  2V3Y A;  2BH3 A;  1O0X A;  1QXW A;  2B3L A;  1XGO A;  4A6W A;  1QXZ A;  4IKT A;  4RGZ 1;  1C22 A;  5CNX A;  4OOK A;  4IEC A;  5CDE A;  4ZWP A;  2P99 A;  2V6C A;  4S01 A;  2Q92 A;  4FLJ A;  2GU6 A;  1WBQ A;  1R58 A;  2ADU A;  5JHU A;  4IU6 A;  1R5G A;  1QXY A;  2Q93 A;  2P98 A;  4FUK A;  5E5B A;  3PKC A;  5FCF A;  1WL9 A;  4U71 A;  1YW9 A;  3CB6 A;  4U73 A;  5D6F A;  3IU7 A;  4U1B A;  2Q95 A;  4U6C A;  1JAW A;  2BB7 A;  2BWT A;  2OAZ A;  2NQ6 A;  4FKC A;  2GU7 A;  5CLS A;  4B28 A;  4FLL A;  2GA2 A;  3Q6D A;  3RVA A;  2GG2 A;  2Q96 A;  4U6W A;  2G6P A;  2EA4 A;  1WL6 A;  2B3H A;  1PV9 A;  4FLK A;  3FM3 A;  1XGM A;  1KQ0 A;  4S2T P;  4QR8 A;  2EVO A;  2GGB A;  2DFI A;  4MAT A;  2GG9 A;  5CIK A;  2Q94 A;  2BHB A;  4FLI A;  4U6Z A;  3IU8 A;  1W7V A;  3BIQ A;  2ZSG A;  2BHD A;  3D27 A;  3MR1 A;  3PKA A;  4FO7 A;  1XGS A;  4ZWO A;  3TB5 A;  2OKN A;  4JUQ A;  2EVC A;  1WLR A;  1MAT A;  4Z7M A;  4RZZ A;  2GTX A;  1W2M A;  1CHM A;  4PV4 A;  3L24 A;  4U6E A;  2BHC A;  5JI6 A;  2BHA A;  1YJ3 A;  1WN1 A;  2EA2 A;  4IKS A;  2HOW A;  2BWU A;  1B6A A;  3CTZ A;  1XNZ A;  1KQ9 A;  1BN5 A;  4HXX A;  4IDY A;  4IKR A;  1BOA A;  1C23 A;  1KP0 A;  4U69 A;  5JFR A;  3MAT A;  4S2R P;  4ZNG A;  4U70 A;  3IG4 A;  2P9A A;  4S00 A;  2IW2 A;  4IF7 A;  5FCH A;  1Y1N A;  4RZY A;  2GG7 A;  2V3Z A;  3ROR A;  2GGC A;  3PKB A;  4ZWU A;  2V3X A;  3S6B A;  3TAV A;  5CDL A;  1A16 A;  1XGN A;  4EGE A;  4FO8 A;  4U75 A;  1N51 A;  3L7G A;  1WY2 A;  3FMR A;  3IU9 A;  3MX6 A;  2BWS A;  3BIT A;  5CE6 A;  4IPA A;  2BWV A;  1C21 A;  1QZY A;  4A6V A;  1M35 A;  1YW8 A;  2Q8K A;  4U6J A;  1C24 A;  2BN7 A;  2GG0 A;  1YVM A; 
#chains in the Genus database with same CATH homology
 1YW7 A;  2GU5 A;  4R60 A;  4IKU A;  1R5H A;  2NQ7 A;  1WKM A;  1B59 A;  2GZ5 A;  4U76 A;  3PKE A;  2BWY A;  4KM3 A;  2BWX A;  5CDV A;  2BWW A;  3BIP A;  2B3K A;  2GG5 A;  1C27 A;  3CB5 A;  3PKD A;  2GU4 A;  4PNC A;  2GG3 A;  2EVM A;  3FMQ A;  5D6E A;  2MAT A;  2GG8 A;  2V3Y A;  2BH3 A;  1O0X A;  1QXW A;  2B3L A;  1XGO A;  4A6W A;  1QXZ A;  4IKT A;  4RGZ 1;  1C22 A;  5CNX A;  4OOK A;  4IEC A;  5CDE A;  4ZWP A;  2P99 A;  2V6C A;  4S01 A;  2Q92 A;  4FLJ A;  2GU6 A;  1WBQ A;  1R58 A;  2ADU A;  5JHU A;  4IU6 A;  1R5G A;  1QXY A;  2Q93 A;  2P98 A;  4FUK A;  5E5B A;  3PKC A;  5FCF A;  1WL9 A;  4U71 A;  1YW9 A;  3CB6 A;  4U73 A;  5D6F A;  3IU7 A;  4U1B A;  2Q95 A;  4U6C A;  1JAW A;  2BB7 A;  2BWT A;  2OAZ A;  2NQ6 A;  4FKC A;  2GU7 A;  5CLS A;  4B28 A;  4FLL A;  2GA2 A;  3Q6D A;  3RVA A;  2GG2 A;  2Q96 A;  4U6W A;  2G6P A;  2EA4 A;  1WL6 A;  2B3H A;  1PV9 A;  4FLK A;  3FM3 A;  1XGM A;  1KQ0 A;  4S2T P;  4QR8 A;  2EVO A;  2GGB A;  2DFI A;  4MAT A;  2GG9 A;  5CIK A;  2Q94 A;  2BHB A;  4FLI A;  4U6Z A;  3IU8 A;  1W7V A;  3BIQ A;  2ZSG A;  2BHD A;  3D27 A;  3MR1 A;  3PKA A;  4FO7 A;  1XGS A;  4ZWO A;  3TB5 A;  2OKN A;  4JUQ A;  2EVC A;  1WLR A;  1MAT A;  4Z7M A;  4RZZ A;  2GTX A;  1W2M A;  1CHM A;  4PV4 A;  3L24 A;  4U6E A;  2BHC A;  5JI6 A;  2BHA A;  1YJ3 A;  1WN1 A;  2EA2 A;  4IKS A;  2HOW A;  2BWU A;  1B6A A;  3CTZ A;  1XNZ A;  1KQ9 A;  1BN5 A;  4HXX A;  4IDY A;  4IKR A;  1BOA A;  1C23 A;  1KP0 A;  4U69 A;  5JFR A;  3MAT A;  4S2R P;  4ZNG A;  4U70 A;  3IG4 A;  2P9A A;  4S00 A;  2IW2 A;  4IF7 A;  5FCH A;  1Y1N A;  4RZY A;  2GG7 A;  2V3Z A;  3ROR A;  2GGC A;  3PKB A;  4ZWU A;  2V3X A;  3S6B A;  3TAV A;  5CDL A;  1A16 A;  1XGN A;  4EGE A;  4FO8 A;  4U75 A;  1N51 A;  3L7G A;  1WY2 A;  3FMR A;  3IU9 A;  3MX6 A;  2BWS A;  3BIT A;  5CE6 A;  4IPA A;  2BWV A;  1C21 A;  1QZY A;  4A6V A;  1M35 A;  1YW8 A;  2Q8K A;  4U6J A;  1C24 A;  2BN7 A;  2GG0 A;  1YVM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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