1C3UA

T. maritima adenylosuccinate lyase
Total Genus 168
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
168
sequence length
429
structure length
423
Chain Sequence
VERYSLSPMKDLWTEEAKYRRWLEVELAVTRAYEELGMIPKGVTERIRNNAKIDVELFKKIEEKTNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISGAVGNYANVPPEVEEKALSYLGLKPEPVSTQVVPRDRHAFYLSTLAIVAAGIERIAVEIRHLQRTEVLEVEEPFRSAMPHKKNPITCERLTGLSRMMRAYVDPSLENIALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSQRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKKLVTKEELEELFDISYYLKHVDHIFERFEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ADENYLOSUCCINATE LYASE
publication title The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.
pubmed doi rcsb
source organism Thermotoga maritima
molecule tags Lyase
total genus 168
structure length 423
sequence length 429
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 1999-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1c3uA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1c3uA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1c3uA02
4FFXA 4MX2A 1FUOA 3BHGA 5EYVA 2OHYA 2QGAB 4ADMA 2PTRA 4EEIA 1J3UA 1I0AA 1VDKA 1Q5NA 1KQ7A 2HVGA 2PTQA 5HW2A 3KDYA 1TJVA 1DOFA 3E04A 1YFEA 3R6YA 4C5UA 3C8TA 1C3CA 4C6GA 3UNVA 1EB4A 2O7EA 1DCNA 1FUQA 3RD8A 1JSWA 4HGVA 2PTSA 2VD6A 3R6VA 2NYFA 4EFCA 4BAAA 1TJ7A 3KDZA 2J91A 2O7FA 3GTDA 1GK3A 3GZHA 1XWOA 3QBPA 5EYTA 1HY1A 2X75A 1AUWA 5F91A 2QVEA 2O7DA 2RJSA 2YIIA 2RJRA 1K7WA 1TJUA 1HY0A 1C3UA 1GKJA 2E9FA 1Y2MA 4NSLA 4APBA 1B8FA 1GKMA 3OCEA 1T6PA 1U15A 2NYNA 1W27A 2O6YA 1TJWA 4CQ5A 2O7BA 3OCFA 2PFMA 1FUPA 4C5RA 4V2QA 2FUSA 4FLCA 4BABA 4ADLA 4C5SA 1RE5A 4NLEA 3NO9A 3RRPA 3TV2A 1YISA 1T6JA 4V2RA 3CZOA 5D6BA 3R6QA 1U16A 3NZ4A 2O78A 1K62A 4APAA 1FURA 1YFMA 5F92A 1GK2A
chains in the Genus database with same CATH superfamily
4FFXA 4MX2A 1FUOA 3BHGA 1Q92A 5EYVA 4E88A 2FELA 4IQJM 2OHYA 2QGAB 3U19A 1XMCA 1XMDA 4ADMA 1XL8A 2PTRA 4EEIA 1J3UA 2JARA 1I0AA 1VDKA 1Q5NA 1KQ7A 2HVGA 1Z4QA 2PTQA 5HW2A 3KDYA 1TJVA 1U0LA 1DOFA 3E04A 1YFEA 3R6YA 4C5UA 4MUMA 3C8TA 1C3CA 2I7DA 4C6GA 1Z4MA 3UNVA 1EB4A 2O7EA 1DCNA 1FUQA 3RD8A 1JSWA 3CI0K 4NFLA 4HGVA 1Z4LA 2PTSA 4MWOA 2VD6A 3R6VA 2NYFA 4EFCA 4BAAA 1IW7D 2RCNA 1TJ7A 3KDZA 2J91A 2O7FA 3GTDA 1T9HA 1GK3A 3GZHA 1XWOA 3QBPA 5EYTA 1HY1A 2X75A 1AUWA 5F91A 2D27A 2QVEA 3CRVA 2O7DA 5H8WA 5M0IA 2RJSA 2YIIA 2RJRA 1K7WA 1TJUA 1HY0A 1C3UA 1GKJA 4A15A 1XL7A 4YIKA 2E9FA 4WNLA 1Y2MA 4NSLA 3F4SA 4APBA 4YIHA 1B8FA 1GKMA 5M0JA 3OCEA 1T6PA 1U15A 2NYNA 1W27A 1Q91A 1Z4PX 1MH9A 2D28C 2VL7A 2O6YA 1TJWA 4CQ5A 3BWVA 3OCFA 2O7BA 2PFMA 2JAUA 2YV5A 1FUPA 4C5RA 4V2QA 2FUSA 4FLCA 4L6AA 4BABA 4ADLA 4C5SA 1RE5A 4NLEA 3NO9A 2JAWA 3RRPA 3TV2A 1YISA 2VSFA 1T6JA 3CRW1 1Z4KA 3F4RA 4L57A 4V2RA 4L6CA 3CZOA 1Z4IA 5D6BA 3R6QA 1U16A 2FENA 3U13A 3NZ4A 2O78A 3F4TA 1K62A 2JAOA 4APAA 1FURA 1YFMA 5F92A 1Z4JA 1GK2A 1XLYA
chains in the Genus database with same CATH topology
4FFXA 4MX2A 1FUOA 3BHGA 5EYVA 2OHYA 2QGAB 4ADMA 2PTRA 4EEIA 1J3UA 1I0AA 1VDKA 1Q5NA 1KQ7A 2HVGA 2PTQA 5HW2A 3KDYA 1TJVA 1DOFA 3E04A 1YFEA 3R6YA 4C5UA 3C8TA 1C3CA 4C6GA 3UNVA 1EB4A 2O7EA 1DCNA 1FUQA 3RD8A 1JSWA 4HGVA 2PTSA 2VD6A 3R6VA 2NYFA 4EFCA 4BAAA 1TJ7A 3KDZA 2J91A 2O7FA 3GTDA 1GK3A 3GZHA 1XWOA 3QBPA 5EYTA 1HY1A 2X75A 1AUWA 5F91A 2QVEA 2O7DA 2RJSA 2YIIA 2RJRA 1K7WA 1TJUA 1HY0A 1C3UA 1GKJA 2E9FA 1Y2MA 4NSLA 4APBA 1B8FA 1GKMA 3OCEA 1T6PA 1U15A 2NYNA 1W27A 2O6YA 1TJWA 4CQ5A 2O7BA 3OCFA 2PFMA 1FUPA 4C5RA 4V2QA 2FUSA 4FLCA 4BABA 4ADLA 4C5SA 1RE5A 4NLEA 3NO9A 3RRPA 3TV2A 1YISA 1T6JA 4V2RA 3CZOA 5D6BA 3R6QA 1U16A 3NZ4A 2O78A 1K62A 4APAA 1FURA 1YFMA 5F92A 1GK2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FFX A;  4MX2 A;  1FUO A;  3BHG A;  5EYV A;  2OHY A;  2QGA B;  4ADM A;  2PTR A;  4EEI A;  1J3U A;  1I0A A;  1VDK A;  1Q5N A;  1KQ7 A;  2HVG A;  2PTQ A;  5HW2 A;  3KDY A;  1TJV A;  1DOF A;  3E04 A;  1YFE A;  3R6Y A;  4C5U A;  3C8T A;  1C3C A;  4C6G A;  3UNV A;  1EB4 A;  2O7E A;  1DCN A;  1FUQ A;  3RD8 A;  1JSW A;  4HGV A;  2PTS A;  2VD6 A;  3R6V A;  2NYF A;  4EFC A;  4BAA A;  1TJ7 A;  3KDZ A;  2J91 A;  2O7F A;  3GTD A;  1GK3 A;  3GZH A;  1XWO A;  3QBP A;  5EYT A;  1HY1 A;  2X75 A;  1AUW A;  5F91 A;  2QVE A;  2O7D A;  2RJS A;  2YII A;  2RJR A;  1K7W A;  1TJU A;  1HY0 A;  1C3U A;  1GKJ A;  2E9F A;  1Y2M A;  4NSL A;  4APB A;  1B8F A;  1GKM A;  3OCE A;  1T6P A;  1U15 A;  2NYN A;  1W27 A;  2O6Y A;  1TJW A;  4CQ5 A;  2O7B A;  3OCF A;  2PFM A;  1FUP A;  4C5R A;  4V2Q A;  2FUS A;  4FLC A;  4BAB A;  4ADL A;  4C5S A;  1RE5 A;  4NLE A;  3NO9 A;  3RRP A;  3TV2 A;  1YIS A;  1T6J A;  4V2R A;  3CZO A;  5D6B A;  3R6Q A;  1U16 A;  3NZ4 A;  2O78 A;  1K62 A;  4APA A;  1FUR A;  1YFM A;  5F92 A;  1GK2 A; 
#chains in the Genus database with same CATH topology
 4FFX A;  4MX2 A;  1FUO A;  3BHG A;  1Q92 A;  5EYV A;  4E88 A;  2FEL A;  4IQJ M;  2OHY A;  2QGA B;  3U19 A;  1XMC A;  1XMD A;  4ADM A;  1XL8 A;  2PTR A;  4EEI A;  1J3U A;  2JAR A;  1I0A A;  1VDK A;  1Q5N A;  1KQ7 A;  2HVG A;  1Z4Q A;  2PTQ A;  5HW2 A;  3KDY A;  1TJV A;  1U0L A;  1DOF A;  3E04 A;  1YFE A;  3R6Y A;  4C5U A;  4MUM A;  3C8T A;  1C3C A;  2I7D A;  4C6G A;  1Z4M A;  3UNV A;  1EB4 A;  2O7E A;  1DCN A;  1FUQ A;  3RD8 A;  1JSW A;  3CI0 K;  4NFL A;  4HGV A;  1Z4L A;  2PTS A;  4MWO A;  2VD6 A;  3R6V A;  2NYF A;  4EFC A;  4BAA A;  1IW7 D;  2RCN A;  1TJ7 A;  3KDZ A;  2J91 A;  2O7F A;  3GTD A;  1T9H A;  1GK3 A;  3GZH A;  1XWO A;  3QBP A;  5EYT A;  1HY1 A;  2X75 A;  1AUW A;  5F91 A;  2D27 A;  2QVE A;  3CRV A;  2O7D A;  5H8W A;  5M0I A;  2RJS A;  2YII A;  2RJR A;  1K7W A;  1TJU A;  1HY0 A;  1C3U A;  1GKJ A;  4A15 A;  1XL7 A;  4YIK A;  2E9F A;  4WNL A;  1Y2M A;  4NSL A;  3F4S A;  4APB A;  4YIH A;  1B8F A;  1GKM A;  5M0J A;  3OCE A;  1T6P A;  1U15 A;  2NYN A;  1W27 A;  1Q91 A;  1Z4P X;  1MH9 A;  2D28 C;  2VL7 A;  2O6Y A;  1TJW A;  4CQ5 A;  3BWV A;  3OCF A;  2O7B A;  2PFM A;  2JAU A;  2YV5 A;  1FUP A;  4C5R A;  4V2Q A;  2FUS A;  4FLC A;  4L6A A;  4BAB A;  4ADL A;  4C5S A;  1RE5 A;  4NLE A;  3NO9 A;  2JAW A;  3RRP A;  3TV2 A;  1YIS A;  2VSF A;  1T6J A;  3CRW 1;  1Z4K A;  3F4R A;  4L57 A;  4V2R A;  4L6C A;  3CZO A;  1Z4I A;  5D6B A;  3R6Q A;  1U16 A;  2FEN A;  3U13 A;  3NZ4 A;  2O78 A;  3F4T A;  1K62 A;  2JAO A;  4APA A;  1FUR A;  1YFM A;  5F92 A;  1Z4J A;  1GK2 A;  1XLY A; 
#chains in the Genus database with same CATH homology
 4FFX A;  4MX2 A;  1FUO A;  3BHG A;  5EYV A;  2OHY A;  2QGA B;  4ADM A;  2PTR A;  4EEI A;  1J3U A;  1I0A A;  1VDK A;  1Q5N A;  1KQ7 A;  2HVG A;  2PTQ A;  5HW2 A;  3KDY A;  1TJV A;  1DOF A;  3E04 A;  1YFE A;  3R6Y A;  4C5U A;  3C8T A;  1C3C A;  4C6G A;  3UNV A;  1EB4 A;  2O7E A;  1DCN A;  1FUQ A;  3RD8 A;  1JSW A;  4HGV A;  2PTS A;  2VD6 A;  3R6V A;  2NYF A;  4EFC A;  4BAA A;  1TJ7 A;  3KDZ A;  2J91 A;  2O7F A;  3GTD A;  1GK3 A;  3GZH A;  1XWO A;  3QBP A;  5EYT A;  1HY1 A;  2X75 A;  1AUW A;  5F91 A;  2QVE A;  2O7D A;  2RJS A;  2YII A;  2RJR A;  1K7W A;  1TJU A;  1HY0 A;  1C3U A;  1GKJ A;  2E9F A;  1Y2M A;  4NSL A;  4APB A;  1B8F A;  1GKM A;  3OCE A;  1T6P A;  1U15 A;  2NYN A;  1W27 A;  2O6Y A;  1TJW A;  4CQ5 A;  2O7B A;  3OCF A;  2PFM A;  1FUP A;  4C5R A;  4V2Q A;  2FUS A;  4FLC A;  4BAB A;  4ADL A;  4C5S A;  1RE5 A;  4NLE A;  3NO9 A;  3RRP A;  3TV2 A;  1YIS A;  1T6J A;  4V2R A;  3CZO A;  5D6B A;  3R6Q A;  1U16 A;  3NZ4 A;  2O78 A;  1K62 A;  4APA A;  1FUR A;  1YFM A;  5F92 A;  1GK2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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