1C3UA

T. maritima adenylosuccinate lyase
Total Genus 168
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
168
sequence length
429
structure length
423
Chain Sequence
VERYSLSPMKDLWTEEAKYRRWLEVELAVTRAYEELGMIPKGVTERIRNNAKIDVELFKKIEEKTNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISGAVGNYANVPPEVEEKALSYLGLKPEPVSTQVVPRDRHAFYLSTLAIVAAGIERIAVEIRHLQRTEVLEVEEPFRSAMPHKKNPITCERLTGLSRMMRAYVDPSLENIALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSQRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKKLVTKEELEELFDISYYLKHVDHIFERFEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ADENYLOSUCCINATE LYASE
publication title The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.
pubmed doi rcsb
source organism Thermotoga maritima
molecule tags Lyase
total genus 168
structure length 423
sequence length 429
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 1999-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1c3uA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1c3uA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1c3uA02
3NZ4A 1K62A 1GK3A 3UNVA 1JSWA 2O6YA 4EEIA 4BABA 4EFCA 1Q5NA 1HY0A 3RRPA 1TJ7A 2RJSA 2OHYA 2YIIA 1U16A 1EB4A 1YISA 4V2RA 1GKMA 2QVEA 4BAAA 1TJUA 3R6VA 4FFXA 2O7FA 4FLCA 4C5SA 1T6PA 2O7BA 1HY1A 5EYTA 2NYNA 1K7WA 1GKJA 2PTSA 1I0AA 1T6JA 5EYVA 2VD6A 1FUQA 1TJVA 5HW2A 2NYFA 1U15A 5F91A 4APBA 1KQ7A 2J91A 2RJRA 3C8TA 1YFEA 2PTQA 4ADMA 1C3CA 2QGAB 3TV2A 4CQ5A 3RD8A 1FUOA 4C5UA 4HGVA 3R6QA 4C6GA 1C3UA 4V2QA 4C5RA 3GTDA 3OCFA 5F92A 3QBPA 4MX2A 3NO9A 1W27A 2FUSA 4ADLA 3GZHA 1DCNA 1Y2MA 2PFMA 1GK2A 2E9FA 2HVGA 5D6BA 1XWOA 3OCEA 3E04A 1FUPA 1YFMA 2O78A 4NSLA 2X75A 3R6YA 4APAA 2O7EA 1AUWA 3KDYA 1TJWA 2PTRA 4NLEA 1J3UA 3CZOA 1B8FA 1FURA 3BHGA 3KDZA 1VDKA 1RE5A 2O7DA 1DOFA
chains in the Genus database with same CATH superfamily
3NZ4A 1K62A 1GK3A 3UNVA 4YIHA 1JSWA 2O6YA 2JAOA 1MH9A 2RCNA 4EEIA 3F4TA 4BABA 2D27A 4EFCA 1Q5NA 1HY0A 2JARA 1TJ7A 3RRPA 2RJSA 2OHYA 2YIIA 1U16A 1EB4A 1YISA 4V2RA 1GKMA 2QVEA 4BAAA 1TJUA 3R6VA 4FFXA 4WNLA 2O7FA 4FLCA 1Z4QA 4C5SA 1Z4LA 1T6PA 2O7BA 1HY1A 5EYTA 2VSFA 2NYNA 1Z4KA 1K7WA 1GKJA 2PTSA 1I0AA 1T6JA 5EYVA 2VD6A 1FUQA 2FENA 1TJVA 5HW2A 2NYFA 1U15A 4YIKA 5F91A 4APBA 1T9HA 3U19A 1KQ7A 3BWVA 2J91A 2RJRA 3C8TA 1YFEA 2PTQA 2FELA 2JAUA 4ADMA 3CRVA 1C3CA 1XL7A 3U13A 2QGAB 3TV2A 4CQ5A 4L6AA 3RD8A 1FUOA 3CRW1 5M0IA 5H8WA 4C5UA 3CI0K 4HGVA 3R6QA 4IQJM 4C6GA 4NFLA 1IW7D 1C3UA 1Q92A 4V2QA 4C5RA 3GTDA 3OCFA 1XLYA 2YV5A 5F92A 4A15A 1Q91A 4MWOA 3QBPA 4L6CA 4MX2A 3NO9A 1W27A 2FUSA 4ADLA 1Z4IA 1XMCA 3GZHA 1DCNA 1Y2MA 2PFMA 1GK2A 2I7DA 2E9FA 2JAWA 1Z4PX 1XMDA 2HVGA 3F4SA 5D6BA 2O7DA 2VL7A 1XWOA 3OCEA 3E04A 1FUPA 1XL8A 1YFMA 2D28C 2O78A 4NSLA 1U0LA 2X75A 4E88A 3R6YA 4APAA 2O7EA 1AUWA 3KDYA 1TJWA 5M0JA 4L57A 2PTRA 4NLEA 1Z4JA 1J3UA 3CZOA 1B8FA 3F4RA 1FURA 3BHGA 3KDZA 1VDKA 1RE5A 4MUMA 1Z4MA 1DOFA
chains in the Genus database with same CATH topology
3NZ4A 1K62A 1GK3A 3UNVA 1JSWA 2O6YA 4EEIA 4BABA 4EFCA 1Q5NA 1HY0A 3RRPA 1TJ7A 2RJSA 2OHYA 2YIIA 1U16A 1EB4A 1YISA 4V2RA 1GKMA 2QVEA 4BAAA 1TJUA 3R6VA 4FFXA 2O7FA 4FLCA 4C5SA 1T6PA 2O7BA 1HY1A 5EYTA 2NYNA 1K7WA 1GKJA 2PTSA 1I0AA 1T6JA 5EYVA 2VD6A 1FUQA 1TJVA 5HW2A 2NYFA 1U15A 5F91A 4APBA 1KQ7A 2J91A 2RJRA 3C8TA 1YFEA 2PTQA 4ADMA 1C3CA 2QGAB 3TV2A 4CQ5A 3RD8A 1FUOA 4C5UA 4HGVA 3R6QA 4C6GA 1C3UA 4V2QA 4C5RA 3GTDA 3OCFA 5F92A 3QBPA 4MX2A 3NO9A 1W27A 2FUSA 4ADLA 3GZHA 1DCNA 1Y2MA 2PFMA 1GK2A 2E9FA 2HVGA 5D6BA 1XWOA 3OCEA 3E04A 1FUPA 1YFMA 2O78A 4NSLA 2X75A 3R6YA 4APAA 2O7EA 1AUWA 3KDYA 1TJWA 2PTRA 4NLEA 1J3UA 3CZOA 1B8FA 1FURA 3BHGA 3KDZA 1VDKA 1RE5A 2O7DA 1DOFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NZ4 A;  1K62 A;  1GK3 A;  3UNV A;  1JSW A;  2O6Y A;  4EEI A;  4BAB A;  4EFC A;  1Q5N A;  1HY0 A;  3RRP A;  1TJ7 A;  2RJS A;  2OHY A;  2YII A;  1U16 A;  1EB4 A;  1YIS A;  4V2R A;  1GKM A;  2QVE A;  4BAA A;  1TJU A;  3R6V A;  4FFX A;  2O7F A;  4FLC A;  4C5S A;  1T6P A;  2O7B A;  1HY1 A;  5EYT A;  2NYN A;  1K7W A;  1GKJ A;  2PTS A;  1I0A A;  1T6J A;  5EYV A;  2VD6 A;  1FUQ A;  1TJV A;  5HW2 A;  2NYF A;  1U15 A;  5F91 A;  4APB A;  1KQ7 A;  2J91 A;  2RJR A;  3C8T A;  1YFE A;  2PTQ A;  4ADM A;  1C3C A;  2QGA B;  3TV2 A;  4CQ5 A;  3RD8 A;  1FUO A;  4C5U A;  4HGV A;  3R6Q A;  4C6G A;  1C3U A;  4V2Q A;  4C5R A;  3GTD A;  3OCF A;  5F92 A;  3QBP A;  4MX2 A;  3NO9 A;  1W27 A;  2FUS A;  4ADL A;  3GZH A;  1DCN A;  1Y2M A;  2PFM A;  1GK2 A;  2E9F A;  2HVG A;  5D6B A;  1XWO A;  3OCE A;  3E04 A;  1FUP A;  1YFM A;  2O78 A;  4NSL A;  2X75 A;  3R6Y A;  4APA A;  2O7E A;  1AUW A;  3KDY A;  1TJW A;  2PTR A;  4NLE A;  1J3U A;  3CZO A;  1B8F A;  1FUR A;  3BHG A;  3KDZ A;  1VDK A;  1RE5 A;  2O7D A;  1DOF A; 
#chains in the Genus database with same CATH topology
 3NZ4 A;  1K62 A;  1GK3 A;  3UNV A;  4YIH A;  1JSW A;  2O6Y A;  2JAO A;  1MH9 A;  2RCN A;  4EEI A;  3F4T A;  4BAB A;  2D27 A;  4EFC A;  1Q5N A;  1HY0 A;  2JAR A;  1TJ7 A;  3RRP A;  2RJS A;  2OHY A;  2YII A;  1U16 A;  1EB4 A;  1YIS A;  4V2R A;  1GKM A;  2QVE A;  4BAA A;  1TJU A;  3R6V A;  4FFX A;  4WNL A;  2O7F A;  4FLC A;  1Z4Q A;  4C5S A;  1Z4L A;  1T6P A;  2O7B A;  1HY1 A;  5EYT A;  2VSF A;  2NYN A;  1Z4K A;  1K7W A;  1GKJ A;  2PTS A;  1I0A A;  1T6J A;  5EYV A;  2VD6 A;  1FUQ A;  2FEN A;  1TJV A;  5HW2 A;  2NYF A;  1U15 A;  4YIK A;  5F91 A;  4APB A;  1T9H A;  3U19 A;  1KQ7 A;  3BWV A;  2J91 A;  2RJR A;  3C8T A;  1YFE A;  2PTQ A;  2FEL A;  2JAU A;  4ADM A;  3CRV A;  1C3C A;  1XL7 A;  3U13 A;  2QGA B;  3TV2 A;  4CQ5 A;  4L6A A;  3RD8 A;  1FUO A;  3CRW 1;  5M0I A;  5H8W A;  4C5U A;  3CI0 K;  4HGV A;  3R6Q A;  4IQJ M;  4C6G A;  4NFL A;  1IW7 D;  1C3U A;  1Q92 A;  4V2Q A;  4C5R A;  3GTD A;  3OCF A;  1XLY A;  2YV5 A;  5F92 A;  4A15 A;  1Q91 A;  4MWO A;  3QBP A;  4L6C A;  4MX2 A;  3NO9 A;  1W27 A;  2FUS A;  4ADL A;  1Z4I A;  1XMC A;  3GZH A;  1DCN A;  1Y2M A;  2PFM A;  1GK2 A;  2I7D A;  2E9F A;  2JAW A;  1Z4P X;  1XMD A;  2HVG A;  3F4S A;  5D6B A;  2O7D A;  2VL7 A;  1XWO A;  3OCE A;  3E04 A;  1FUP A;  1XL8 A;  1YFM A;  2D28 C;  2O78 A;  4NSL A;  1U0L A;  2X75 A;  4E88 A;  3R6Y A;  4APA A;  2O7E A;  1AUW A;  3KDY A;  1TJW A;  5M0J A;  4L57 A;  2PTR A;  4NLE A;  1Z4J A;  1J3U A;  3CZO A;  1B8F A;  3F4R A;  1FUR A;  3BHG A;  3KDZ A;  1VDK A;  1RE5 A;  4MUM A;  1Z4M A;  1DOF A; 
#chains in the Genus database with same CATH homology
 3NZ4 A;  1K62 A;  1GK3 A;  3UNV A;  1JSW A;  2O6Y A;  4EEI A;  4BAB A;  4EFC A;  1Q5N A;  1HY0 A;  3RRP A;  1TJ7 A;  2RJS A;  2OHY A;  2YII A;  1U16 A;  1EB4 A;  1YIS A;  4V2R A;  1GKM A;  2QVE A;  4BAA A;  1TJU A;  3R6V A;  4FFX A;  2O7F A;  4FLC A;  4C5S A;  1T6P A;  2O7B A;  1HY1 A;  5EYT A;  2NYN A;  1K7W A;  1GKJ A;  2PTS A;  1I0A A;  1T6J A;  5EYV A;  2VD6 A;  1FUQ A;  1TJV A;  5HW2 A;  2NYF A;  1U15 A;  5F91 A;  4APB A;  1KQ7 A;  2J91 A;  2RJR A;  3C8T A;  1YFE A;  2PTQ A;  4ADM A;  1C3C A;  2QGA B;  3TV2 A;  4CQ5 A;  3RD8 A;  1FUO A;  4C5U A;  4HGV A;  3R6Q A;  4C6G A;  1C3U A;  4V2Q A;  4C5R A;  3GTD A;  3OCF A;  5F92 A;  3QBP A;  4MX2 A;  3NO9 A;  1W27 A;  2FUS A;  4ADL A;  3GZH A;  1DCN A;  1Y2M A;  2PFM A;  1GK2 A;  2E9F A;  2HVG A;  5D6B A;  1XWO A;  3OCE A;  3E04 A;  1FUP A;  1YFM A;  2O78 A;  4NSL A;  2X75 A;  3R6Y A;  4APA A;  2O7E A;  1AUW A;  3KDY A;  1TJW A;  2PTR A;  4NLE A;  1J3U A;  3CZO A;  1B8F A;  1FUR A;  3BHG A;  3KDZ A;  1VDK A;  1RE5 A;  2O7D A;  1DOF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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