1C82A

Mechanism of hyaluronan binding and degradation: structure of streptococcus pneumoniae hyaluronate lyase in complex with hyaluronic acid disaccharide at 1.7 a resolution
Total Genus 254
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
254
sequence length
719
structure length
719
Chain Sequence
KDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords HYALURONATE LYASE
publication title Mechanism of hyaluronan binding and degradation: structure of Streptococcus pneumoniae hyaluronate lyase in complex with hyaluronic acid disaccharide at 1.7 A resolution.
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
total genus 254
structure length 719
sequence length 719
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2000-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1c82A02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1c82A03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1c82A01
3DYOA 1N7QA 1W3YA 1MN0A 1NSVA 4D6JA 5A1AA 3DYMA 2HTBA 3T0BA 4AQ0A 4OZVA 1JYWA 1LF6A 4D6DA 3VSMA 2BRWA 1LURA 1HMUA 2WDAA 2JKPA 1OJPA 3NJVA 3Q1NA 3BGAA 3A24A 1JZ2A 1JZ5A 1NS0A 1QAZA 2WVXB 2WW2A 4BZEA 4D6EA 1UG9A 1X1JA 2WW3A 1K1WA 2WMJA 1I8QA 1N7NA 3VDAA 3MUY1 2FUQA 3VD3A 1MMZA 1J0NA 3J7HA 5JMFA 1HN0A 1RW9A 1YGAA 2JKAA 2WMIB 1MMXA 1NS8A 1HMWA 1NSSA 1JZ4A 1LXKA 4BZFA 4D6HA 3NREA 1RWAA 4MMHA 3ECQA 3K25A 1JZ3A 3VD9A 1F9GA 1EGUA 1F4HA 1NS2A 1LOHA 1NSRA 1X1HA 1J0MA 1JZ7A 4NEIA 2WVYA 2XSGA 1F1SA 1K1XA 2BRVX 1NS4A 4BZHA 1PX3A 4D6GA 1RWCA 4DUXA 1HV6A 1OJOA 1RWFA 1HN1A 1NSZA 1NKGA 1JYVA 4FNVA 2WMHA 2Q1FA 3VDBA 2CIQA 1K1YA 3T0AA 2WCOA 1L7KA 3WFAA 1MMUA 4RNLA 1OJNA 2D73A 2WMFA 1X1IA 3NNBA 4D71A 1F4AA 1HM2A 3I3BA 4TTGA 1N7RA 3CZJA 2WMKA 2HTAA 2WW0A 3T2QA 3DECA 1C82A 4OJZA 1OJMA 4MMIA 1HM3A 3IAPA 4OK4A 4D6CA 2WZSA 2CIRA 2X03A 1Z45A 1L7JA 2CISA 3I3DA 1NS7A 2WVXA 1NSXA 2ZXQA 3DCDA 1RWGA 1N7PA 3OBAA 3AFLA 1JZ8A 4F10A 2JKEA 2E22A 3T2OA 3VDCA 1PX4A 3E1F1 3T0DA 3VD5A 2WMGA 2BRPA 1LXMA 1JOVA 1NSUA 1TXKA 3NFVA 1JZ6A 4D72A 4D6IA 2WW1A 1MMYA 2FUTA 3NJXA 4D6FA 2WVZA 4DUVA 4OZWA 4OK2A 3OS7A 4F13A 3T2PA 3E80A 3VD4A 1RWHA 1SO0A 3I3EA 2ZQ0A 1LF9A 3MV01 1CB8A 5E1QA 1JYNA 2E24A 1YQ2A 3T08A 2XHNA 4E1YA 3MUZ1 3IAQA 1NSMA 1N7OA 4BZGA 1ULVA 3VSNA 3A0OA 3T09A 1SNZA 1JYXA 1DP0A 5JMDA 2WMIA 3VD7A 4DUWA 3E7JA 3SEPA 3MV11 3DYPA 3OB8A 3IMHA 3MWXA
chains in the Genus database with same CATH superfamily
2RDYA 3PYBA 3N0GA 2I07B 1MN0A 2HTBA 3M73A 1O6QA 4OZVA 1JYWA 3VSMA 4DLQA 2BRWA 2WY7A 5ILYA 4MU9A 3OXUA 3BGAA 2SQCA 4BOJA 3QR8A 1QAZA 3Q73B 2XN0A 1UG9A 2NVPA 3AMOA 3QPFA 2EADA 1V5DA 4ZG8A 1RKYA 3KBTC 5FO9B 1UI8A 1AYXA 1NI1B 5IK0A 3BVUA 1JCQB 1N1ZA 2DROA 1PU4A 5EAUA 3DSUB 3RRSA 5C05A 1H3CA 3G4FA 1HWWA 3EJUA 4BZFA 4L9PB 1F9GA 2C11A 4YCRA 1NC5A 4YDEB 1LOHA 1RQ5A 1TN8B 1QAFA 3X3YA 4GTRB 2YIKA 3ACSA 2XSGA 3Q7FB 1W4NA 4FNPA 1RWCA 4D4CA 1US1A 4ZH1A 3KN4A 1LD8B 4JJJA 1RWFA 3HXCB 3WIRA 2RI9A 3W7TA 4FNVA 2WMHA 1HTYA 1KWFA 3VDBA 1AGMA 1IVWA 3PZ2B 3HIIA 3T0AA 3EQAA 1MMUA 2D73A 1IVUA 3G4DA 3ANIA 3I3BA 1TQUA 2OOVC 4FJQA 3M02A 1L1YA 2CISA 1Z45A 3KSLB 1O1SB 1L7JA 5IM1A 1TNBB 1G6IA 1H54A 1VD5A 4WVCA 3PGBA 4DOEA 3DSVB 3WKIA 5EASA 3D4ZA 1TNOB 1LXMA 3MI6A 3SDTA 2CFLA 1TXKA 1R33A 3UD2A 3KIIA 2G0DA 4D72A 4BTYA 3GLYA 4FNRA 1WU6A 1UMPA 2XQWA 4DUVA 2PMVA 5GY3A 2DRRA 5IKHA 2CFDA 4LNBB 3WKHA 1N95B 2ONGA 4K3AA 3VD4A 3W5MA 3I3EA 3BVWA 4Q88A 2A73B 3M75A 3K5TA 1SIIA 3S4AA 4GTPB 4CJ0A 4BTXA 5IK9A 2H6HB 3EU5B 1TF4A 2XHNA 4E1YA 4GAXA 3DRAB 1KFGA 1WMOA 1N7OA 2CFWA 2F7PA 4MBGB 5IKAA 3VSNA 1EKMA 1N24A 1TNUB 2YX9A 1DP0A 5JMDA 4DUWA 2WYHA 4YDOB 3WC3A 3DX0A 2WO0A 3RSYA 2Y74A 1F9DA 5GW7A 3HXBB 3RENA 3MPHA 1TN6B 3W7UA 1D8DB 3T0BA 4AQ0A 3NBBA 3M7EA 1LURA 1WU5A 3P5PA 3D5RA 3Q1NA 1FO2A 1JZ2A 3M77A 3D51A 2V3NA 1CEMA 1V7VA 1X1JA 2CQTA 3W7SA 1K1WA 3QWTA 2G02A 3MUY1 1N94B 1XWTA 3DSXB 3J7HA 1FP3A 3X41A 5JMFA 1HN0A 1TQSA 1N4QB 2JKAA 3WA2X 1XWQA 1NS8A 1A2VA 2YFNA 1NSSA 3KLSA 1RJOA 1N4SB 4D6HA 2E2TA 2OW7A 1RWAA 4MMHA 1IA7A 3S4CA 2XFGA 3ECQA 3VD9A 4WU0A 3M74A 3CZSA 4QT9A 3CIHA 2C10A 4GTSB 1HZFA 4KFFA 3QG0A 1H3BA 1JZ7A 3QXQA 3LOYA 3WIWA 1KSCA 1NL4B 2FV0A 3RX8A 3QDEA 1K1XA 1NS4A 3BVXA 3X3ZA 4BZHA 2XN2A 4D6GA 1TQVA 5E2JA 2EABA 3ANKA 1HN1A 1NSZA 1LD7B 1NKGA 3DSTB 2FYVA 2Q1FA 1G9GA 3GT5A 2CIQA 3DX3A 1K1YA 2WCOA 3SXXA 1OJNA 2F1BA 3NNBA 4D71A 2J5CA 2KXRA 1HXKA 2PNCA 1OACA 3BS6A 1AVKA 3DECA 4OJZA 3WA3A 3M01A 4MMIA 4UFCA 3TF4A 3RX5A 2ZIRB 1W6CA 2CG0A 2E2UA 4L0GA 1FBWA 4D6CA 2B4FA 2CG1A 3WUXA 2WZSA 5CZLA 3SAEA 5M7IA 2WVXA 1RWGA 1N7PA 2FBAA 1QALA 4ZH5A 2D5JA 5IL3A 3D4YA 4EHMB 3KSQB 3X40A 3VDCA 3HXEB 4L6XA 2OQEC 2KXSA 1SA4B 3X17A 1TNZB 3BUBA 1TN7B 2GZ6A 3VXDA 1QAKA 1GHQA 4FNQA 4DLOA 2FUTA 2DRQA 4D8OA 2OKXA 4D6FA 2WVZA 4OZWA 4OK2A 1FT1B 2ZISB 4KKIA 4V1RA 4D4DA 4F13A 3WIQA 3M00A 5CD2A 1IQYA 3SFXB 1L2AA 3K11A 1H3AA 1WMNA 3KBUC 1KKTA 3SQCA 2PN5A 2CWVA 1H37A 5E1QA 1DCEB 1JYNA 1TQTA 3BVTA 3EJPA 4BOKA 3W7WA 1FO3A 3MUZ1 3IAQA 1JRQA 3PZ4B 3A3VA 4BZGA 3PZ3B 3DDGA 3W7XA 3A0OA 2F7QA 3S4BA 1AVLA 3VD7A 4TXTA 1PS3A 1W7CA 1D6ZA 1FPPB 4FXKB 3IMHA 4Z4JA 1X9DA 2H6GB 2F1AA 1N7QA 1W3YA 3TY1A 1NSVA 5FO8B 3DYMA 3EU8A 1D8EB 2CFGA 3CU7A 3SFYB 3X42A 4LNVA 1LF6A 3D52A 4RNQA 2CQSA 1HMUA 2F18A 2ALWA 2JKPA 2R2LB 1V7XA 3LZ9A 4XUVA 2ZBLA 3VW5A 3A24A 1JZ5A 4EL8A 1NS0A 5MEHA 2WVXB 1N9EA 5KKBA 4D6EA 2WW3A 3H3KA 3EJTA 3OEDA 2WMJA 3DSWB 3QFZA 3VDAA 4M76A 2CWTA 2FUQA 3VD3A 1N23A 1FAEA 1MMZA 2DRSA 5IK6A 5DHIA 5ILDA 1GA2A 1YGAA 2WMIB 1NXCA 2F7OA 2WYNA 1HMWA 1JZ4A 1LXKA 3PMMA 1DOGA 5M7YA 2V3PA 4KFDA 1S63B 1JZ3A 2EAEA 3ALAA 1SPUA 1F4HA 1X1HA 2WGQA 1V7WA 1J0MA 3Q79B 4NEIA 4D4AA 1F1SA 2WINB 3BLCA 2B39A 2V8IA 3D5SA 2JG0A 1W6JA 1HV6A 1O6RA 1QSJA 5ILIA 2D8LA 3X3XA 1JYVA 2IEJB 5AGDA 3WFAA 2ZZRA 4Q2BA 4AYPA 1JCSB 1HXCA 1O7DD 3E34B 3BUDA 4J5TA 1F4AA 5CA3A 1HM2A 1N20A 3SX1A 5ILJA 2VN7A 1QX1A 1K72A 1HX9A 2WMKA 2HTAA 3T2QA 2RI8A 1C82A 1OJMA 2JF4A 1HM3A 4OK4A 1DYUA 3BVVA 2FV1A 2V8KA 3C72B 4WVAA 1R34A 2F7RA 4FNSA 1KREA 3I3DA 1XW2A 3UD1A 4FUSA 4FNTA 1CLCA 1NS7A 1NSXA 3SDUA 2ZXQA 3DCDA 1X81B 3OBAA 3AFLA 2F6DA 1S64B 3PQIA 2JKEA 3P2CA 2E22A 3M7BA 1LVNA 3ACTA 2ZL8A 3LVTA 1IA6A 1FCEA 3Q75B 5JPMB 3ANJA 1W6GA 3F59A 1O6HA 2Z07A 4GTOB 2BRPA 2AFAA 3VD5A 1JOVA 1NSUA 1JZ6A 3GZKA 3H7LA 3E30B 2BB6A 4D6IA 2WW1A 1MMYA 2BB5A 1H39A 3K7XA 3S9VA 4DI5A 1HXAA 3HXFB 4GTTB 3HI7A 3OS7A 2VN4A 1N1BA 2WIIB 3EZ8A 3Q7AB 1H13A 2JJBA 3HXDB 1DL2A 3T2PA 4KFEA 3E80A 1GXNA 1KZPB 2NOJA 1KS8A 4WVBA 3HIGA 3DX4A 4LIXA 1LF9A 2QNOA 1LTXB 2E24A 1AV4A 3QFYA 3T08A 1QQFA 1NSMA 1GAIA 1N21A 1W5ZA 1N9AB 1JYXA 4AYRA 1O1RB 2WMIA 1H36A 1SA5B 3E7JA 2AHGA 1QWUA 2CFKA 3MV11 4GL3A 3M78A 4GTVB 3EJSA 4AYOA 3E73A 5DGRA 3OB8A 3MWXA 1FMIA 1V5CA 1H12A 3DYOA 3EJQA 2OQEA 3DPYB 5DGQA 1H14A 4D6JA 3M72A 3WKFA 5A1AA 4AYQA 3DDFA 4ZRQA 2XN1A 4D1IA 3RJ3A 4D6DA 1F9OA 3QXFA 3EJRA 2WDAA 5DHKA 4K35A 1OJPA 4TF4A 1JCRB 3NJVA 1N4PB 3T33A 1SQCA 2WW2A 4BZEA 1G87A 2XWBB 5FOBB 1H35A 1GAHA 1KRFA 4GTQB 3Q78B 2FUZA 1I8QA 1JS4A 1N7NA 2H6FB 2OOVA 3QT3A 1IVXA 2GOXA 4EV5A 3M7LA 1J0NA 1UI7A 3BUPA 3PYAA 1IU7A 2BT3A 3T0UA 1O79A 1RW9A 2H6IB 1O1TB 1QBQB 1MMXA 3E37B 4CJ1A 1GXOA 3BUIA 2WOHA 1TQWA 3CZNA 3NREA 5IL8A 3WKGA 3N9HA 3K25A 1TNYB 3E6UA 4KTRA 4CE7A 1EGUA 4ZRPA 1W6KA 3S4DA 3G6JB 1IVVA 1NS2A 1NSRA 3H2WA 1O5MB 1FT2B 1D6YA 2WVYA 5KBPA 1UT9A 2GH4A 4C1SA 2BRVX 3RX7A 3M7CA 5ILZA 1PX3A 3E33B 3EUVB 4DUXA 4D4BA 1GXMA 1OJOA 3M76A 4DODA 1D6UA 5EATA 3AMOB 4EV2A 2A8ZA 4D1JA 1L7KA 1WMPA 4RNLA 2EACA 1WU4A 1X1IA 2WMFA 2W0QA 1GLMA 1N7RA 4TTGA 2OW6A 4FXGB 3BLBA 3CZJA 2F0YB 3N0FA 2WW0A 2D1WA 4D94A 1HCUA 3D3IA 4GTMB 3DX1A 3IAPA 1W2ZA 1QWNA 3NBJA 1IS9A 1KSDA 2CIRA 2X03A 3SDQA 2ONHA 3KQ4A 5FO7B 1TU5A 1JZ8A 2WYIA 4F10A 4FNUA 1MZCB 2RGKA 3T2OA 1PX4A 3E1F1 3DSSB 3SDRA 3CV5A 3U7VA 3DX2A 3T0DA 3QSPA 5JPNB 5GZKA 2BBCA 2WMGA 2WOFA 3WVFA 4KKJA 1IQXA 3NFVA 3BUQA 2E2VA 3NJXA 3AFJA 3ON6A 2WY8A 3PZ1B 1N22A 3P5RA 1HXGA 4ONTA 3W5NA 4LNGB 3QT9A 1FBOA 1RWHA 1SO0A 2V8JA 2ZQ0A 3MV01 5ILKA 1CB8A 2CWUA 1YQ2A 1R76A 5ILHA 3D50A 4V1SA 1KZOB 4KTPA 3SDVA 3E32B 1SIHA 1N4RB 1ULVA 2BEDB 1WZZA 3T09A 1SNZA 3QRYA 2XWJB 1C3DA 3M71A 4Z4LA 1KSIA 2Y73A 2YFOA 1G9JA 3SEPA 3DYPA 4BTWA 2AHFA 2P0VA 1GSZA
chains in the Genus database with same CATH topology
3DYOA 1N7QA 1W3YA 3TY1A 1MN0A 1NSVA 4D6JA 5A1AA 3DYMA 2HTBA 3T0BA 4AQ0A 4OZVA 1JYWA 1LF6A 4D6DA 3VSMA 2BRWA 1LURA 1HMUA 2WDAA 2JKPA 1OJPA 3NJVA 3Q1NA 3BGAA 3A24A 1JZ2A 1JZ5A 1NS0A 1QAZA 2WVXB 2WW2A 4BZEA 4D6EA 1UG9A 1X1JA 2WW3A 1K1WA 2WMJA 1I8QA 1N7NA 3VDAA 3MUY1 2FUQA 3VD3A 1MMZA 1J0NA 3J7HA 5JMFA 1HN0A 1RW9A 1YGAA 2JKAA 2WMIB 1MMXA 1NS8A 1HMWA 1NSSA 1JZ4A 1LXKA 4BZFA 4D6HA 3NREA 1RWAA 4MMHA 3ECQA 3K25A 1JZ3A 3VD9A 1F9GA 1EGUA 1F4HA 1NS2A 1LOHA 1NSRA 1X1HA 1J0MA 1JZ7A 4NEIA 2WVYA 2XSGA 1F1SA 1K1XA 3BLCA 2BRVX 1NS4A 4BZHA 1PX3A 4D6GA 1RWCA 4DUXA 1HV6A 1OJOA 1RWFA 1HN1A 1NSZA 1NKGA 1JYVA 4FNVA 2WMHA 2Q1FA 3VDBA 2CIQA 1K1YA 3T0AA 2WCOA 1L7KA 3WFAA 1MMUA 4RNLA 1OJNA 2D73A 2WMFA 1X1IA 3NNBA 4D71A 1F4AA 4J5TA 1HM2A 3I3BA 4TTGA 1N7RA 3CZJA 3BS6A 2WMKA 2HTAA 2WW0A 3T2QA 3DECA 1C82A 4OJZA 1OJMA 4MMIA 1HM3A 3IAPA 4OK4A 4D6CA 2WZSA 2CIRA 2X03A 1Z45A 1L7JA 2CISA 3I3DA 1NS7A 2WVXA 1NSXA 2ZXQA 3DCDA 1RWGA 1N7PA 3OBAA 3AFLA 1JZ8A 4F10A 2JKEA 2E22A 3T2OA 3VDCA 1PX4A 3E1F1 3T0DA 3VD5A 2WMGA 2BRPA 1LXMA 3WVFA 1JOVA 1NSUA 1TXKA 3NFVA 1JZ6A 4D72A 4D6IA 2WW1A 1MMYA 2FUTA 3NJXA 4D6FA 2WVZA 4DUVA 4OZWA 4OK2A 3OS7A 4F13A 3T2PA 3E80A 3VD4A 1RWHA 1SO0A 3I3EA 2ZQ0A 1LF9A 3MV01 1CB8A 5E1QA 1JYNA 2E24A 1YQ2A 3T08A 2XHNA 4E1YA 3MUZ1 3IAQA 1NSMA 1N7OA 4BZGA 1ULVA 3VSNA 3A0OA 3T09A 1SNZA 1JYXA 1DP0A 5JMDA 2WMIA 3VD7A 4DUWA 3E7JA 3SEPA 3MV11 3DYPA 3OB8A 3IMHA 3MWXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DYO A;  1N7Q A;  1W3Y A;  1MN0 A;  1NSV A;  4D6J A;  5A1A A;  3DYM A;  2HTB A;  3T0B A;  4AQ0 A;  4OZV A;  1JYW A;  1LF6 A;  4D6D A;  3VSM A;  2BRW A;  1LUR A;  1HMU A;  2WDA A;  2JKP A;  1OJP A;  3NJV A;  3Q1N A;  3BGA A;  3A24 A;  1JZ2 A;  1JZ5 A;  1NS0 A;  1QAZ A;  2WVX B;  2WW2 A;  4BZE A;  4D6E A;  1UG9 A;  1X1J A;  2WW3 A;  1K1W A;  2WMJ A;  1I8Q A;  1N7N A;  3VDA A;  3MUY 1;  2FUQ A;  3VD3 A;  1MMZ A;  1J0N A;  3J7H A;  5JMF A;  1HN0 A;  1RW9 A;  1YGA A;  2JKA A;  2WMI B;  1MMX A;  1NS8 A;  1HMW A;  1NSS A;  1JZ4 A;  1LXK A;  4BZF A;  4D6H A;  3NRE A;  1RWA A;  4MMH A;  3ECQ A;  3K25 A;  1JZ3 A;  3VD9 A;  1F9G A;  1EGU A;  1F4H A;  1NS2 A;  1LOH A;  1NSR A;  1X1H A;  1J0M A;  1JZ7 A;  4NEI A;  2WVY A;  2XSG A;  1F1S A;  1K1X A;  2BRV X;  1NS4 A;  4BZH A;  1PX3 A;  4D6G A;  1RWC A;  4DUX A;  1HV6 A;  1OJO A;  1RWF A;  1HN1 A;  1NSZ A;  1NKG A;  1JYV A;  4FNV A;  2WMH A;  2Q1F A;  3VDB A;  2CIQ A;  1K1Y A;  3T0A A;  2WCO A;  1L7K A;  3WFA A;  1MMU A;  4RNL A;  1OJN A;  2D73 A;  2WMF A;  1X1I A;  3NNB A;  4D71 A;  1F4A A;  1HM2 A;  3I3B A;  4TTG A;  1N7R A;  3CZJ A;  2WMK A;  2HTA A;  2WW0 A;  3T2Q A;  3DEC A;  1C82 A;  4OJZ A;  1OJM A;  4MMI A;  1HM3 A;  3IAP A;  4OK4 A;  4D6C A;  2WZS A;  2CIR A;  2X03 A;  1Z45 A;  1L7J A;  2CIS A;  3I3D A;  1NS7 A;  2WVX A;  1NSX A;  2ZXQ A;  3DCD A;  1RWG A;  1N7P A;  3OBA A;  3AFL A;  1JZ8 A;  4F10 A;  2JKE A;  2E22 A;  3T2O A;  3VDC A;  1PX4 A;  3E1F 1;  3T0D A;  3VD5 A;  2WMG A;  2BRP A;  1LXM A;  1JOV A;  1NSU A;  1TXK A;  3NFV A;  1JZ6 A;  4D72 A;  4D6I A;  2WW1 A;  1MMY A;  2FUT A;  3NJX A;  4D6F A;  2WVZ A;  4DUV A;  4OZW A;  4OK2 A;  3OS7 A;  4F13 A;  3T2P A;  3E80 A;  3VD4 A;  1RWH A;  1SO0 A;  3I3E A;  2ZQ0 A;  1LF9 A;  3MV0 1;  1CB8 A;  5E1Q A;  1JYN A;  2E24 A;  1YQ2 A;  3T08 A;  2XHN A;  4E1Y A;  3MUZ 1;  3IAQ A;  1NSM A;  1N7O A;  4BZG A;  1ULV A;  3VSN A;  3A0O A;  3T09 A;  1SNZ A;  1JYX A;  1DP0 A;  5JMD A;  2WMI A;  3VD7 A;  4DUW A;  3E7J A;  3SEP A;  3MV1 1;  3DYP A;  3OB8 A;  3IMH A;  3MWX A; 
#chains in the Genus database with same CATH topology
 2RDY A;  3PYB A;  3N0G A;  2I07 B;  1MN0 A;  2HTB A;  3M73 A;  1O6Q A;  4OZV A;  1JYW A;  3VSM A;  4DLQ A;  2BRW A;  2WY7 A;  5ILY A;  4MU9 A;  3OXU A;  3BGA A;  2SQC A;  4BOJ A;  3QR8 A;  1QAZ A;  3Q73 B;  2XN0 A;  1UG9 A;  2NVP A;  3AMO A;  3QPF A;  2EAD A;  1V5D A;  4ZG8 A;  1RKY A;  3KBT C;  5FO9 B;  1UI8 A;  1AYX A;  1NI1 B;  5IK0 A;  3BVU A;  1JCQ B;  1N1Z A;  2DRO A;  1PU4 A;  5EAU A;  3DSU B;  3RRS A;  5C05 A;  1H3C A;  3G4F A;  1HWW A;  3EJU A;  4BZF A;  4L9P B;  1F9G A;  2C11 A;  4YCR A;  1NC5 A;  4YDE B;  1LOH A;  1RQ5 A;  1TN8 B;  1QAF A;  3X3Y A;  4GTR B;  2YIK A;  3ACS A;  2XSG A;  3Q7F B;  1W4N A;  4FNP A;  1RWC A;  4D4C A;  1US1 A;  4ZH1 A;  3KN4 A;  1LD8 B;  4JJJ A;  1RWF A;  3HXC B;  3WIR A;  2RI9 A;  3W7T A;  4FNV A;  2WMH A;  1HTY A;  1KWF A;  3VDB A;  1AGM A;  1IVW A;  3PZ2 B;  3HII A;  3T0A A;  3EQA A;  1MMU A;  2D73 A;  1IVU A;  3G4D A;  3ANI A;  3I3B A;  1TQU A;  2OOV C;  4FJQ A;  3M02 A;  1L1Y A;  2CIS A;  1Z45 A;  3KSL B;  1O1S B;  1L7J A;  5IM1 A;  1TNB B;  1G6I A;  1H54 A;  1VD5 A;  4WVC A;  3PGB A;  4DOE A;  3DSV B;  3WKI A;  5EAS A;  3D4Z A;  1TNO B;  1LXM A;  3MI6 A;  3SDT A;  2CFL A;  1TXK A;  1R33 A;  3UD2 A;  3KII A;  2G0D A;  4D72 A;  4BTY A;  3GLY A;  4FNR A;  1WU6 A;  1UMP A;  2XQW A;  4DUV A;  2PMV A;  5GY3 A;  2DRR A;  5IKH A;  2CFD A;  4LNB B;  3WKH A;  1N95 B;  2ONG A;  4K3A A;  3VD4 A;  3W5M A;  3I3E A;  3BVW A;  4Q88 A;  2A73 B;  3M75 A;  3K5T A;  1SII A;  3S4A A;  4GTP B;  4CJ0 A;  4BTX A;  5IK9 A;  2H6H B;  3EU5 B;  1TF4 A;  2XHN A;  4E1Y A;  4GAX A;  3DRA B;  1KFG A;  1WMO A;  1N7O A;  2CFW A;  2F7P A;  4MBG B;  5IKA A;  3VSN A;  1EKM A;  1N24 A;  1TNU B;  2YX9 A;  1DP0 A;  5JMD A;  4DUW A;  2WYH A;  4YDO B;  3WC3 A;  3DX0 A;  2WO0 A;  3RSY A;  2Y74 A;  1F9D A;  5GW7 A;  3HXB B;  3REN A;  3MPH A;  1TN6 B;  3W7U A;  1D8D B;  3T0B A;  4AQ0 A;  3NBB A;  3M7E A;  1LUR A;  1WU5 A;  3P5P A;  3D5R A;  3Q1N A;  1FO2 A;  1JZ2 A;  3M77 A;  3D51 A;  2V3N A;  1CEM A;  1V7V A;  1X1J A;  2CQT A;  3W7S A;  1K1W A;  3QWT A;  2G02 A;  3MUY 1;  1N94 B;  1XWT A;  3DSX B;  3J7H A;  1FP3 A;  3X41 A;  5JMF A;  1HN0 A;  1TQS A;  1N4Q B;  2JKA A;  3WA2 X;  1XWQ A;  1NS8 A;  1A2V A;  2YFN A;  1NSS A;  3KLS A;  1RJO A;  1N4S B;  4D6H A;  2E2T A;  2OW7 A;  1RWA A;  4MMH A;  1IA7 A;  3S4C A;  2XFG A;  3ECQ A;  3VD9 A;  4WU0 A;  3M74 A;  3CZS A;  4QT9 A;  3CIH A;  2C10 A;  4GTS B;  1HZF A;  4KFF A;  3QG0 A;  1H3B A;  1JZ7 A;  3QXQ A;  3LOY A;  3WIW A;  1KSC A;  1NL4 B;  2FV0 A;  3RX8 A;  3QDE A;  1K1X A;  1NS4 A;  3BVX A;  3X3Z A;  4BZH A;  2XN2 A;  4D6G A;  1TQV A;  5E2J A;  2EAB A;  3ANK A;  1HN1 A;  1NSZ A;  1LD7 B;  1NKG A;  3DST B;  2FYV A;  2Q1F A;  1G9G A;  3GT5 A;  2CIQ A;  3DX3 A;  1K1Y A;  2WCO A;  3SXX A;  1OJN A;  2F1B A;  3NNB A;  4D71 A;  2J5C A;  2KXR A;  1HXK A;  2PNC A;  1OAC A;  3BS6 A;  1AVK A;  3DEC A;  4OJZ A;  3WA3 A;  3M01 A;  4MMI A;  4UFC A;  3TF4 A;  3RX5 A;  2ZIR B;  1W6C A;  2CG0 A;  2E2U A;  4L0G A;  1FBW A;  4D6C A;  2B4F A;  2CG1 A;  3WUX A;  2WZS A;  5CZL A;  3SAE A;  5M7I A;  2WVX A;  1RWG A;  1N7P A;  2FBA A;  1QAL A;  4ZH5 A;  2D5J A;  5IL3 A;  3D4Y A;  4EHM B;  3KSQ B;  3X40 A;  3VDC A;  3HXE B;  4L6X A;  2OQE C;  2KXS A;  1SA4 B;  3X17 A;  1TNZ B;  3BUB A;  1TN7 B;  2GZ6 A;  3VXD A;  1QAK A;  1GHQ A;  4FNQ A;  4DLO A;  2FUT A;  2DRQ A;  4D8O A;  2OKX A;  4D6F A;  2WVZ A;  4OZW A;  4OK2 A;  1FT1 B;  2ZIS B;  4KKI A;  4V1R A;  4D4D A;  4F13 A;  3WIQ A;  3M00 A;  5CD2 A;  1IQY A;  3SFX B;  1L2A A;  3K11 A;  1H3A A;  1WMN A;  3KBU C;  1KKT A;  3SQC A;  2PN5 A;  2CWV A;  1H37 A;  5E1Q A;  1DCE B;  1JYN A;  1TQT A;  3BVT A;  3EJP A;  4BOK A;  3W7W A;  1FO3 A;  3MUZ 1;  3IAQ A;  1JRQ A;  3PZ4 B;  3A3V A;  4BZG A;  3PZ3 B;  3DDG A;  3W7X A;  3A0O A;  2F7Q A;  3S4B A;  1AVL A;  3VD7 A;  4TXT A;  1PS3 A;  1W7C A;  1D6Z A;  1FPP B;  4FXK B;  3IMH A;  4Z4J A;  1X9D A;  2H6G B;  2F1A A;  1N7Q A;  1W3Y A;  3TY1 A;  1NSV A;  5FO8 B;  3DYM A;  3EU8 A;  1D8E B;  2CFG A;  3CU7 A;  3SFY B;  3X42 A;  4LNV A;  1LF6 A;  3D52 A;  4RNQ A;  2CQS A;  1HMU A;  2F18 A;  2ALW A;  2JKP A;  2R2L B;  1V7X A;  3LZ9 A;  4XUV A;  2ZBL A;  3VW5 A;  3A24 A;  1JZ5 A;  4EL8 A;  1NS0 A;  5MEH A;  2WVX B;  1N9E A;  5KKB A;  4D6E A;  2WW3 A;  3H3K A;  3EJT A;  3OED A;  2WMJ A;  3DSW B;  3QFZ A;  3VDA A;  4M76 A;  2CWT A;  2FUQ A;  3VD3 A;  1N23 A;  1FAE A;  1MMZ A;  2DRS A;  5IK6 A;  5DHI A;  5ILD A;  1GA2 A;  1YGA A;  2WMI B;  1NXC A;  2F7O A;  2WYN A;  1HMW A;  1JZ4 A;  1LXK A;  3PMM A;  1DOG A;  5M7Y A;  2V3P A;  4KFD A;  1S63 B;  1JZ3 A;  2EAE A;  3ALA A;  1SPU A;  1F4H A;  1X1H A;  2WGQ A;  1V7W A;  1J0M A;  3Q79 B;  4NEI A;  4D4A A;  1F1S A;  2WIN B;  3BLC A;  2B39 A;  2V8I A;  3D5S A;  2JG0 A;  1W6J A;  1HV6 A;  1O6R A;  1QSJ A;  5ILI A;  2D8L A;  3X3X A;  1JYV A;  2IEJ B;  5AGD A;  3WFA A;  2ZZR A;  4Q2B A;  4AYP A;  1JCS B;  1HXC A;  1O7D D;  3E34 B;  3BUD A;  4J5T A;  1F4A A;  5CA3 A;  1HM2 A;  1N20 A;  3SX1 A;  5ILJ A;  2VN7 A;  1QX1 A;  1K72 A;  1HX9 A;  2WMK A;  2HTA A;  3T2Q A;  2RI8 A;  1C82 A;  1OJM A;  2JF4 A;  1HM3 A;  4OK4 A;  1DYU A;  3BVV A;  2FV1 A;  2V8K A;  3C72 B;  4WVA A;  1R34 A;  2F7R A;  4FNS A;  1KRE A;  3I3D A;  1XW2 A;  3UD1 A;  4FUS A;  4FNT A;  1CLC A;  1NS7 A;  1NSX A;  3SDU A;  2ZXQ A;  3DCD A;  1X81 B;  3OBA A;  3AFL A;  2F6D A;  1S64 B;  3PQI A;  2JKE A;  3P2C A;  2E22 A;  3M7B A;  1LVN A;  3ACT A;  2ZL8 A;  3LVT A;  1IA6 A;  1FCE A;  3Q75 B;  5JPM B;  3ANJ A;  1W6G A;  3F59 A;  1O6H A;  2Z07 A;  4GTO B;  2BRP A;  2AFA A;  3VD5 A;  1JOV A;  1NSU A;  1JZ6 A;  3GZK A;  3H7L A;  3E30 B;  2BB6 A;  4D6I A;  2WW1 A;  1MMY A;  2BB5 A;  1H39 A;  3K7X A;  3S9V A;  4DI5 A;  1HXA A;  3HXF B;  4GTT B;  3HI7 A;  3OS7 A;  2VN4 A;  1N1B A;  2WII B;  3EZ8 A;  3Q7A B;  1H13 A;  2JJB A;  3HXD B;  1DL2 A;  3T2P A;  4KFE A;  3E80 A;  1GXN A;  1KZP B;  2NOJ A;  1KS8 A;  4WVB A;  3HIG A;  3DX4 A;  4LIX A;  1LF9 A;  2QNO A;  1LTX B;  2E24 A;  1AV4 A;  3QFY A;  3T08 A;  1QQF A;  1NSM A;  1GAI A;  1N21 A;  1W5Z A;  1N9A B;  1JYX A;  4AYR A;  1O1R B;  2WMI A;  1H36 A;  1SA5 B;  3E7J A;  2AHG A;  1QWU A;  2CFK A;  3MV1 1;  4GL3 A;  3M78 A;  4GTV B;  3EJS A;  4AYO A;  3E73 A;  5DGR A;  3OB8 A;  3MWX A;  1FMI A;  1V5C A;  1H12 A;  3DYO A;  3EJQ A;  2OQE A;  3DPY B;  5DGQ A;  1H14 A;  4D6J A;  3M72 A;  3WKF A;  5A1A A;  4AYQ A;  3DDF A;  4ZRQ A;  2XN1 A;  4D1I A;  3RJ3 A;  4D6D A;  1F9O A;  3QXF A;  3EJR A;  2WDA A;  5DHK A;  4K35 A;  1OJP A;  4TF4 A;  1JCR B;  3NJV A;  1N4P B;  3T33 A;  1SQC A;  2WW2 A;  4BZE A;  1G87 A;  2XWB B;  5FOB B;  1H35 A;  1GAH A;  1KRF A;  4GTQ B;  3Q78 B;  2FUZ A;  1I8Q A;  1JS4 A;  1N7N A;  2H6F B;  2OOV A;  3QT3 A;  1IVX A;  2GOX A;  4EV5 A;  3M7L A;  1J0N A;  1UI7 A;  3BUP A;  3PYA A;  1IU7 A;  2BT3 A;  3T0U A;  1O79 A;  1RW9 A;  2H6I B;  1O1T B;  1QBQ B;  1MMX A;  3E37 B;  4CJ1 A;  1GXO A;  3BUI A;  2WOH A;  1TQW A;  3CZN A;  3NRE A;  5IL8 A;  3WKG A;  3N9H A;  3K25 A;  1TNY B;  3E6U A;  4KTR A;  4CE7 A;  1EGU A;  4ZRP A;  1W6K A;  3S4D A;  3G6J B;  1IVV A;  1NS2 A;  1NSR A;  3H2W A;  1O5M B;  1FT2 B;  1D6Y A;  2WVY A;  5KBP A;  1UT9 A;  2GH4 A;  4C1S A;  2BRV X;  3RX7 A;  3M7C A;  5ILZ A;  1PX3 A;  3E33 B;  3EUV B;  4DUX A;  4D4B A;  1GXM A;  1OJO A;  3M76 A;  4DOD A;  1D6U A;  5EAT A;  3AMO B;  4EV2 A;  2A8Z A;  4D1J A;  1L7K A;  1WMP A;  4RNL A;  2EAC A;  1WU4 A;  1X1I A;  2WMF A;  2W0Q A;  1GLM A;  1N7R A;  4TTG A;  2OW6 A;  4FXG B;  3BLB A;  3CZJ A;  2F0Y B;  3N0F A;  2WW0 A;  2D1W A;  4D94 A;  1HCU A;  3D3I A;  4GTM B;  3DX1 A;  3IAP A;  1W2Z A;  1QWN A;  3NBJ A;  1IS9 A;  1KSD A;  2CIR A;  2X03 A;  3SDQ A;  2ONH A;  3KQ4 A;  5FO7 B;  1TU5 A;  1JZ8 A;  2WYI A;  4F10 A;  4FNU A;  1MZC B;  2RGK A;  3T2O A;  1PX4 A;  3E1F 1;  3DSS B;  3SDR A;  3CV5 A;  3U7V A;  3DX2 A;  3T0D A;  3QSP A;  5JPN B;  5GZK A;  2BBC A;  2WMG A;  2WOF A;  3WVF A;  4KKJ A;  1IQX A;  3NFV A;  3BUQ A;  2E2V A;  3NJX A;  3AFJ A;  3ON6 A;  2WY8 A;  3PZ1 B;  1N22 A;  3P5R A;  1HXG A;  4ONT A;  3W5N A;  4LNG B;  3QT9 A;  1FBO A;  1RWH A;  1SO0 A;  2V8J A;  2ZQ0 A;  3MV0 1;  5ILK A;  1CB8 A;  2CWU A;  1YQ2 A;  1R76 A;  5ILH A;  3D50 A;  4V1S A;  1KZO B;  4KTP A;  3SDV A;  3E32 B;  1SIH A;  1N4R B;  1ULV A;  2BED B;  1WZZ A;  3T09 A;  1SNZ A;  3QRY A;  2XWJ B;  1C3D A;  3M71 A;  4Z4L A;  1KSI A;  2Y73 A;  2YFO A;  1G9J A;  3SEP A;  3DYP A;  4BTW A;  2AHF A;  2P0V A;  1GSZ A; 
#chains in the Genus database with same CATH homology
 3DYO A;  1N7Q A;  1W3Y A;  3TY1 A;  1MN0 A;  1NSV A;  4D6J A;  5A1A A;  3DYM A;  2HTB A;  3T0B A;  4AQ0 A;  4OZV A;  1JYW A;  1LF6 A;  4D6D A;  3VSM A;  2BRW A;  1LUR A;  1HMU A;  2WDA A;  2JKP A;  1OJP A;  3NJV A;  3Q1N A;  3BGA A;  3A24 A;  1JZ2 A;  1JZ5 A;  1NS0 A;  1QAZ A;  2WVX B;  2WW2 A;  4BZE A;  4D6E A;  1UG9 A;  1X1J A;  2WW3 A;  1K1W A;  2WMJ A;  1I8Q A;  1N7N A;  3VDA A;  3MUY 1;  2FUQ A;  3VD3 A;  1MMZ A;  1J0N A;  3J7H A;  5JMF A;  1HN0 A;  1RW9 A;  1YGA A;  2JKA A;  2WMI B;  1MMX A;  1NS8 A;  1HMW A;  1NSS A;  1JZ4 A;  1LXK A;  4BZF A;  4D6H A;  3NRE A;  1RWA A;  4MMH A;  3ECQ A;  3K25 A;  1JZ3 A;  3VD9 A;  1F9G A;  1EGU A;  1F4H A;  1NS2 A;  1LOH A;  1NSR A;  1X1H A;  1J0M A;  1JZ7 A;  4NEI A;  2WVY A;  2XSG A;  1F1S A;  1K1X A;  3BLC A;  2BRV X;  1NS4 A;  4BZH A;  1PX3 A;  4D6G A;  1RWC A;  4DUX A;  1HV6 A;  1OJO A;  1RWF A;  1HN1 A;  1NSZ A;  1NKG A;  1JYV A;  4FNV A;  2WMH A;  2Q1F A;  3VDB A;  2CIQ A;  1K1Y A;  3T0A A;  2WCO A;  1L7K A;  3WFA A;  1MMU A;  4RNL A;  1OJN A;  2D73 A;  2WMF A;  1X1I A;  3NNB A;  4D71 A;  1F4A A;  4J5T A;  1HM2 A;  3I3B A;  4TTG A;  1N7R A;  3CZJ A;  3BS6 A;  2WMK A;  2HTA A;  2WW0 A;  3T2Q A;  3DEC A;  1C82 A;  4OJZ A;  1OJM A;  4MMI A;  1HM3 A;  3IAP A;  4OK4 A;  4D6C A;  2WZS A;  2CIR A;  2X03 A;  1Z45 A;  1L7J A;  2CIS A;  3I3D A;  1NS7 A;  2WVX A;  1NSX A;  2ZXQ A;  3DCD A;  1RWG A;  1N7P A;  3OBA A;  3AFL A;  1JZ8 A;  4F10 A;  2JKE A;  2E22 A;  3T2O A;  3VDC A;  1PX4 A;  3E1F 1;  3T0D A;  3VD5 A;  2WMG A;  2BRP A;  1LXM A;  3WVF A;  1JOV A;  1NSU A;  1TXK A;  3NFV A;  1JZ6 A;  4D72 A;  4D6I A;  2WW1 A;  1MMY A;  2FUT A;  3NJX A;  4D6F A;  2WVZ A;  4DUV A;  4OZW A;  4OK2 A;  3OS7 A;  4F13 A;  3T2P A;  3E80 A;  3VD4 A;  1RWH A;  1SO0 A;  3I3E A;  2ZQ0 A;  1LF9 A;  3MV0 1;  1CB8 A;  5E1Q A;  1JYN A;  2E24 A;  1YQ2 A;  3T08 A;  2XHN A;  4E1Y A;  3MUZ 1;  3IAQ A;  1NSM A;  1N7O A;  4BZG A;  1ULV A;  3VSN A;  3A0O A;  3T09 A;  1SNZ A;  1JYX A;  1DP0 A;  5JMD A;  2WMI A;  3VD7 A;  4DUW A;  3E7J A;  3SEP A;  3MV1 1;  3DYP A;  3OB8 A;  3IMH A;  3MWX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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