1C87A

Crystal structure of protein tyrosine phosphatase 1b complexed with 2-(oxalyl-amino-4,7-dihydro-5h-thieno[2,3-c]pyran-3-carboxylic acid
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKTYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLDMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN (PROTEIN-TYROSINE PHOSPHATASE 1B)
total genus 107
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1c87A00
2P4DA 5KA4A 4PVGA 5KA2A 1OEVA 3ZM3A 3SR9A 5GTJA 2P6XA 1WRMA 1KAKA 2B4UA 4RHGA 2MBCA 1C85A 4TVVA 2F46A 1XM2A 2H4KA 4NX8A 2E0TA 2H03A 5KA9A 3D1QA 3F9AA 1ECVA 2I6OA 1T49A 3AWGA 3NMEA 2F6ZA 1ZCLA 2OUDA 1I9TA 4I8NA 2NTAA 2PQ5A 1PA1A 1NL9A 3BLUA 3I7ZA 2OC3A 1RXDA 4QBWA 2SHPA 1PTTA 1QZ0A 3ZMQA 4HJQA 2A3KA 1NNYA 4Y14A 5EHPA 4NYHA 1L8GA 2H02A 1WCHA 1I57A 1KAVA 1FQ1A 1BZHA 2FJMA 1YTNA 1NZ7A 4R0SA 2QBSA 3S3EA 4GRYA 1G1GA 2J17A 1ZZWA 3QCBA 2NV5A 4RI4A 5KABA 2PA5A 5BUGA 2CNIA 3O3LA 2QDCA 2NZ6A 1U25A 3LJ8A 3S3HA 1Q6TA 2J16A 2CM2A 2QCJA 2BIJA 4D3RA 2ESBA 2CFVA 2HCMA 3V0JA 4QAPA 3GXHA 4QUMA 4OHHA 1T4JA 4YR8B 3GXGA 4MBBA 3RGOA 1LYVA 3M4UA 3ZM1A 3BRHA 3V0DA 4OHEA 1PA9A 1YPTA 3RGQA 2AZRA 3RZ2A 1YGUA 3H2XA 3QCFA 5K9WA 3BM8A 2I1YA 2I6MA 2NLKA 4BJOA 3QCLA 2I6IA 4J51A 4R30A 3PS5A 2HY3A 3MOZA 1L8KA 1X24A 1OEUA 4R0TA 1C87A 2CNGA 4AZ1A 2I5XA 2BGEA 5M43A 4QBEA 3V0HA 1D5RA 3D42A 3F9BA 4KI9A 5KA3A 1PH0A 2PI7A 2Y96A 4ZRTA 1ZCKA 3V0EA 3EU0A 4GS0A 1YFOA 1GWZA 5KA0A 4RI5A 3QKQA 4IKCA 2FH7A 4RKKA 1U26A 2F71A 2B07A 5KAAA 2F70A 2CJZA 3A5KA 1FPZA 1OETA 2RF6A 1LQFA 3V0IA 4KYRA 5KA7A 2IMGA 1XRIA 4DGXA 3U96A 1OHCA 1I9SA 4WU2A 2I42A 4JBCA 5J8RA 1C84A 3ZV2A 2ZN7A 4H1OA 4D3PA 1YZ4A 1SUGA 1RPMA 1V3AA 2CMBA 1R6HA 2CM8A 3RO1A 1XBOA 2I4HA 1ZC0A 2C46A 2DXPA 4Z6BA 2H4GA 1ONYA 2PBNA 1J4XA 2Q05A 3QCHA 4JNBA 3O4TA 4Y2EA 3I36A 2WGPA 1G4WR 3QCEA 5KA1A 2I4GA 1C88A 3D1HA 3SMEA 3D9CA 5LXQB 3D1OA 3EMUA 1Q6MA 5K23A 2C7SA 1C86A 2M3VA 2PT0A 2ZMMA 2CNEA 5KACA 3ZM2A 1EENA 1EEOA 4ICZA 2H04A 4GFUA 4OHIA 3S4OA 3QCJA 2OZ5A 5BX1A 1YGRA 1YTWA 2AHSA 2A8BA 5BZXA 4JMJA 3EB1A 1GFYA 1PXHA 3ZMPA 2B4OA 1NO6A 1P15A 3MMJA 3O4SA 2I3RA 1U24A 2CMCA 3QKPA 4B04A 4GRZA 1OEOX 2HNQA 2I4EA 2PSZA 2Q47A 3B7OA 3OLRA 5EHRA 3QCKA 1OEMX 1OHEA 3F41A 4ZI4A 2F6TA 4D3QA 2QCTA 2B4PA 2OOQA 4HRFA 3I80A 1YWFA 5K9VA 2VEWA 4HJPA 4QUNA 4RDDA 1ONZA 4WU3A 4S0GA 2HVLA 2JJDA 5BZZA 1G1FA 1VHRA 1Q6SA 5MMZB 5K22A 4ZN5A 2GJTA 3EAXA 3F81A 3O5XA 2NT7A 4H34A 3MOWA 4BPCA 1OHDA 1Q6PA 2Y2FA 3O4UA 3D44A 2VEVA 3AWEA 4NNDA 3QCGA 4GE2A 1PYNA 1C83A 4OHLA 2HB1A 1G7FA 5K25A 3ZM0A 1JLNA 2VEUA 1Q6JA 3S4EA 2BGDA 2HXPA 3QCDA 4QAHA 5IBSA 4YAAA 2HC2A 5KADA 1BZCA 5KA8A 4PYHA 1WAXA 4WOHA 5K24A 1PTYA 2B4SA 1YTSA 2QBRA 2B3OA 2R0BA 2J16B 2F6VA 2CM3A 4GE5A 4DGPA 1XXVA 1NWEA 2F6FA 2I6PA 3CWEA 1JF7A 4OHDA 4KYQA 3V0FA 2QDPA 2G6ZA 1M3GA 3N0AA 2VEYA 1Q1MA 3OMHA 2I6JA 5AWXA 3V0GA 3AWFA 5IBMA 4NWFA 1NWLA 1G1HA 1BZJA 2QDMA 1YN9A 2CNFA 4ERCA 4GWFA 1T48A 3S3KA 2HNPA 3F99A 1QXKA 3CM3A 1MKPA 4GFVA 1PTUA 1LARA 2B49A 2FJNA 2BZLA 1G7GA 2QEPA 3QCMA 1FPRA 5I6VA 4GE6A 1XXPA 1OESA 4WTYA 2CM7A 2CNHA 2YDUA 2NT2A 2BV5A 2G59A 3S3FA 2H4VA 2QBPA 1Q6NA 2GP0A 2F6YA 2HC1A 3QCIA 2GWOA 3EZZA 4NWGA 5HDEA 2F6WA 2QBQA 2VEXA 4RH9A 3QCNA 2I3UA 2CMAA 3QCCA 1A5YA 3BLTA 3A5JA 1AAXA 1G4US 1PTVA 2I75A 4JMKA 4RH5A
chains in the Genus database with same CATH superfamily
2P4DA 5KA4A 4PVGA 5KA2A 1OEVA 3ZM3A 3SR9A 5GTJA 2P6XA 1WRMA 1KAKA 2B4UA 4RHGA 2MBCA 1C85A 4TVVA 2F46A 1XM2A 2H4KA 4NX8A 2E0TA 2H03A 5KA9A 3D1QA 3F9AA 1ECVA 2I6OA 1T49A 3AWGA 3NMEA 2F6ZA 3QCZA 1ZCLA 2OUDA 1I9TA 4I8NA 2NTAA 2PQ5A 1PA1A 1NL9A 3BLUA 3I7ZA 2OC3A 1RXDA 4QBWA 2SHPA 1PTTA 1QZ0A 3ZMQA 4HJQA 2A3KA 1NNYA 4Y14A 5EHPA 4NYHA 1L8GA 2H02A 1WCHA 1I57A 1KAVA 2XPCA 1FQ1A 1BZHA 2FJMA 1YTNA 1NZ7A 4R0SA 2QBSA 3S3EA 4GRYA 1G1GA 2J17A 1FGSA 1ZZWA 3QCBA 2NV5A 4RI4A 5KABA 2PA5A 5BUGA 2CNIA 2UUOA 3O3LA 2QDCA 2NZ6A 1U25A 3LJ8A 4QF5A 3S3HA 1Q6TA 2J16A 2CM2A 2QCJA 2BIJA 4D3RA 2ESBA 2CFVA 2HCMA 3V0JA 4QAPA 3GXHA 4C12A 4QUMA 4OHHA 5A5FA 1T4JA 4YR8B 2JFFA 3GXGA 4MBBA 3RGOA 1LYVA 3M4UA 3ZM1A 2GCAA 3BRHA 3V0DA 4OHEA 1PA9A 1YPTA 3RGQA 2AZRA 3RZ2A 1YGUA 3H2XA 3QCFA 2WJPA 3MVNA 5K9WA 3BM8A 2I1YA 2I6MA 2NLKA 4BJOA 3QCLA 2I6IA 4J51A 4R30A 3PS5A 2HY3A 3MOZA 1L8KA 1X24A 1OEUA 4R0TA 1C87A 2CNGA 4AZ1A 2I5XA 2BGEA 5M43A 4QBEA 3V0HA 1D5RA 3D42A 3F9BA 4KI9A 5KA3A 1PH0A 2PI7A 2Y96A 3ZL8A 4ZRTA 1ZCKA 3V0EA 3EU0A 1O5ZA 4GS0A 1YFOA 1GWZA 3UAGA 5KA0A 4RI5A 3QKQA 4IKCA 2FH7A 4RKKA 1U26A 2F71A 2B07A 5KAAA 2F70A 2CJZA 3A5KA 1FPZA 1OETA 2RF6A 1LQFA 3V0IA 4KYRA 5KA7A 2IMGA 1XRIA 4DGXA 3U96A 1OHCA 1P3DA 1I9SA 1GQQA 2I42A 4WU2A 4JBCA 5J8RA 1C84A 2X5OA 3ZV2A 2VOSA 2ZN7A 4BUBA 4H1OA 4D3PA 2VORA 1YZ4A 1SUGA 1RPMA 1V3AA 2CMBA 1R6HA 2CM8A 1GG4A 3RO1A 1XBOA 2I4HA 3NRSA 1ZC0A 2F00A 2C46A 2DXPA 2GCBA 4Z6BA 2H4GA 1ONYA 2PBNA 1J4XA 4CVLA 2Q05A 3QCHA 4JNBA 3O4TA 4Y2EA 2JFHA 3I36A 2WGPA 1G4WR 3QCEA 5KA1A 2I4GA 1C88A 3D1HA 3SMEA 3D9CA 5LXQB 3D1OA 3EMUA 1Q6MA 2Y1OA 5K23A 2C7SA 1C86A 2M3VA 2PT0A 2ZMMA 3LK7A 2CNEA 5KACA 3ZM2A 1EENA 1EEOA 2UUPA 4ICZA 2H04A 4GFUA 4OHIA 3S4OA 3QCJA 2OZ5A 5BX1A 1YGRA 1YTWA 2AHSA 2A8BA 5BZXA 4JMJA 3EB1A 1GFYA 1PXHA 2AM2A 2GC6A 3ZMPA 2B4OA 1NO6A 1P15A 3MMJA 3O4SA 2I3RA 1U24A 2CMCA 3QKPA 4B04A 4GRZA 1OEOX 2HNQA 2I4EA 2PSZA 2Q47A 2WTZA 3B7OA 3OLRA 5EHRA 3QCKA 1OEMX 1OHEA 3F41A 4ZI4A 2F6TA 1UAGA 4D3QA 3PYZA 2QCTA 2B4PA 2OOQA 4HRFA 3I80A 1YWFA 5K9VA 2VEWA 4HJPA 4QUNA 4RDDA 4UAGA 1W7KA 1E0DA 1ONZA 4S0GA 4WU3A 2JFGA 2XJAA 2HVLA 1EEHA 2JJDA 5BZZA 4ZIYA 1G1FA 1VHRA 1Q6SA 5MMZB 5K22A 4ZN5A 2GJTA 1J6UA 3EAXA 3F81A 3O5XA 2NT7A 4H34A 3MOWA 4BPCA 2UAGA 1OHDA 1Q6PA 2Y2FA 4C13A 3O4UA 3D44A 2VEVA 3AWEA 3ZM6A 4NNDA 3QCGA 4GE2A 1PYNA 1C83A 4OHLA 2VTEA 2HB1A 1G7FA 5K25A 2Y66A 3ZM0A 1JLNA 2VEUA 1Q6JA 1P31A 3S4EA 2BGDA 2HXPA 3QCDA 4QAHA 5IBSA 4YAAA 2HC2A 5KADA 1BZCA 5KA8A 4PYHA 4CVKA 1WAXA 2GC5A 4WOHA 5K24A 1PTYA 2B4SA 1YTSA 2QBRA 2B3OA 1JBVA 2R0BA 5A5EA 2J16B 2F6VA 2CM3A 1E8CA 4GE5A 4DGPA 1XXVA 1NWEA 1W78A 2F6FA 2I6PA 3CWEA 1JF7A 4OHDA 4KYQA 3V0FA 2QDPA 2Y67A 2G6ZA 1M3GA 3N0AA 2VEYA 1Q1MA 3OMHA 2I6JA 5AWXA 3V0GA 1JBWA 3AWFA 5IBMA 4NWFA 1NWLA 1G1HA 3N2AA 1BZJA 2QDMA 1GQYA 1YN9A 2CNFA 4ERCA 4GWFA 1T48A 3S3KA 2HNPA 3F99A 1QXKA 3CM3A 1MKPA 4GFVA 3ZM5A 4CVMA 1PTUA 1LARA 2B49A 2FJNA 2BZLA 1G7GA 2QEPA 3QCMA 4QDIA 1FPRA 2VTDA 4GE6A 5I6VA 1XXPA 1OESA 2Y68A 4WTYA 2CM7A 2CNHA 2YDUA 2NT2A 2BV5A 2G59A 3S3FA 2H4VA 2QBPA 1Q6NA 2GP0A 4BUCA 4HV4A 2F6YA 2HC1A 3QCIA 2GWOA 3EZZA 4NWGA 5HDEA 2F6WA 2QBQA 2VEXA 4RH9A 3QCNA 2I3UA 2CMAA 2AM1A 3QCCA 1A5YA 3BLTA 3HN7A 3A5JA 1AAXA 1G4US 1PTVA 2I75A 4JMKA 4RH5A
chains in the Genus database with same CATH topology
2P4DA 5KA4A 4PVGA 5KA2A 1OEVA 3ZM3A 3SR9A 5GTJA 2P6XA 1WRMA 1KAKA 2B4UA 4RHGA 2MBCA 1C85A 4TVVA 2F46A 1XM2A 2H4KA 4NX8A 2E0TA 2H03A 5KA9A 3D1QA 3F9AA 1ECVA 2I6OA 1T49A 3AWGA 3NMEA 2F6ZA 1ZCLA 2OUDA 1I9TA 4I8NA 2NTAA 2PQ5A 1PA1A 1NL9A 3BLUA 3I7ZA 2OC3A 1RXDA 4QBWA 2SHPA 1PTTA 1QZ0A 3ZMQA 4HJQA 2A3KA 1NNYA 4Y14A 5EHPA 4NYHA 1L8GA 2H02A 1WCHA 1I57A 1KAVA 1FQ1A 1BZHA 2FJMA 1YTNA 1NZ7A 4R0SA 2QBSA 3S3EA 4GRYA 1G1GA 2J17A 1ZZWA 3QCBA 2NV5A 4RI4A 5KABA 2PA5A 5BUGA 2CNIA 3O3LA 2QDCA 2NZ6A 1U25A 3LJ8A 3S3HA 1Q6TA 2J16A 2CM2A 2QCJA 2BIJA 4D3RA 2ESBA 2CFVA 2HCMA 3V0JA 4QAPA 3GXHA 4QUMA 4OHHA 1T4JA 4YR8B 3GXGA 4MBBA 3RGOA 1LYVA 3M4UA 3ZM1A 3BRHA 3V0DA 4OHEA 1PA9A 1YPTA 3RGQA 2AZRA 3RZ2A 1YGUA 3H2XA 3QCFA 5K9WA 3BM8A 2I1YA 2I6MA 2NLKA 4BJOA 3QCLA 2I6IA 4J51A 4R30A 3PS5A 2HY3A 3MOZA 1L8KA 1X24A 1OEUA 4R0TA 1C87A 2CNGA 4AZ1A 2I5XA 2BGEA 5M43A 4QBEA 3V0HA 1D5RA 3D42A 3F9BA 4KI9A 5KA3A 1PH0A 2PI7A 2Y96A 4ZRTA 1ZCKA 3V0EA 3EU0A 4GS0A 1YFOA 1GWZA 5KA0A 4RI5A 3QKQA 4IKCA 2FH7A 4RKKA 1U26A 2F71A 2B07A 5KAAA 2F70A 2CJZA 3A5KA 1FPZA 1OETA 2RF6A 1LQFA 3V0IA 4KYRA 5KA7A 2IMGA 1XRIA 4DGXA 3U96A 1OHCA 1I9SA 4WU2A 2I42A 4JBCA 5J8RA 1C84A 3ZV2A 2ZN7A 4H1OA 4D3PA 1YZ4A 1SUGA 1RPMA 1V3AA 2CMBA 1R6HA 2CM8A 3RO1A 1XBOA 2I4HA 1ZC0A 2C46A 2DXPA 4Z6BA 2H4GA 1ONYA 2PBNA 1J4XA 2Q05A 3QCHA 4JNBA 3O4TA 4Y2EA 3I36A 2WGPA 1G4WR 3QCEA 5KA1A 2I4GA 1C88A 3D1HA 3SMEA 3D9CA 5LXQB 3D1OA 3EMUA 1Q6MA 5K23A 2C7SA 1C86A 2M3VA 2PT0A 2ZMMA 2CNEA 5KACA 3ZM2A 1EENA 1EEOA 4ICZA 2H04A 4GFUA 4OHIA 3S4OA 3QCJA 2OZ5A 5BX1A 1YGRA 1YTWA 2AHSA 2A8BA 5BZXA 4JMJA 3EB1A 1GFYA 1PXHA 3ZMPA 2B4OA 1NO6A 1P15A 3MMJA 3O4SA 2I3RA 1U24A 2CMCA 3QKPA 4B04A 4GRZA 1OEOX 2HNQA 2I4EA 2PSZA 2Q47A 3B7OA 3OLRA 5EHRA 3QCKA 1OEMX 1OHEA 3F41A 4ZI4A 2F6TA 4D3QA 2QCTA 2B4PA 2OOQA 4HRFA 3I80A 1YWFA 5K9VA 2VEWA 4HJPA 4QUNA 4RDDA 1ONZA 4WU3A 4S0GA 2HVLA 2JJDA 5BZZA 1G1FA 1VHRA 1Q6SA 5MMZB 5K22A 4ZN5A 2GJTA 3EAXA 3F81A 3O5XA 2NT7A 4H34A 3MOWA 4BPCA 1OHDA 1Q6PA 2Y2FA 3O4UA 3D44A 2VEVA 3AWEA 4NNDA 3QCGA 4GE2A 1PYNA 1C83A 4OHLA 2HB1A 1G7FA 5K25A 3ZM0A 1JLNA 2VEUA 1Q6JA 3S4EA 2BGDA 2HXPA 3QCDA 4QAHA 5IBSA 4YAAA 2HC2A 5KADA 1BZCA 5KA8A 4PYHA 1WAXA 4WOHA 5K24A 1PTYA 2B4SA 1YTSA 2QBRA 2B3OA 2R0BA 2J16B 2F6VA 2CM3A 4GE5A 4DGPA 1XXVA 1NWEA 2F6FA 2I6PA 3CWEA 1JF7A 4OHDA 4KYQA 3V0FA 2QDPA 2G6ZA 1M3GA 3N0AA 2VEYA 1Q1MA 3OMHA 2I6JA 5AWXA 3V0GA 3AWFA 5IBMA 4NWFA 1NWLA 1G1HA 1BZJA 2QDMA 1YN9A 2CNFA 4ERCA 4GWFA 1T48A 3S3KA 2HNPA 3F99A 1QXKA 3CM3A 1MKPA 4GFVA 1PTUA 1LARA 2B49A 2FJNA 2BZLA 1G7GA 2QEPA 3QCMA 1FPRA 5I6VA 4GE6A 1XXPA 1OESA 4WTYA 2CM7A 2CNHA 2YDUA 2NT2A 2BV5A 2G59A 3S3FA 2H4VA 2QBPA 1Q6NA 2GP0A 2F6YA 2HC1A 3QCIA 2GWOA 3EZZA 4NWGA 5HDEA 2F6WA 2QBQA 2VEXA 4RH9A 3QCNA 2I3UA 2CMAA 3QCCA 1A5YA 3BLTA 3A5JA 1AAXA 1G4US 1PTVA 2I75A 4JMKA 4RH5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P4D A;  5KA4 A;  4PVG A;  5KA2 A;  1OEV A;  3ZM3 A;  3SR9 A;  5GTJ A;  2P6X A;  1WRM A;  1KAK A;  2B4U A;  4RHG A;  2MBC A;  1C85 A;  4TVV A;  2F46 A;  1XM2 A;  2H4K A;  4NX8 A;  2E0T A;  2H03 A;  5KA9 A;  3D1Q A;  3F9A A;  1ECV A;  2I6O A;  1T49 A;  3AWG A;  3NME A;  2F6Z A;  1ZCL A;  2OUD A;  1I9T A;  4I8N A;  2NTA A;  2PQ5 A;  1PA1 A;  1NL9 A;  3BLU A;  3I7Z A;  2OC3 A;  1RXD A;  4QBW A;  2SHP A;  1PTT A;  1QZ0 A;  3ZMQ A;  4HJQ A;  2A3K A;  1NNY A;  4Y14 A;  5EHP A;  4NYH A;  1L8G A;  2H02 A;  1WCH A;  1I57 A;  1KAV A;  1FQ1 A;  1BZH A;  2FJM A;  1YTN A;  1NZ7 A;  4R0S A;  2QBS A;  3S3E A;  4GRY A;  1G1G A;  2J17 A;  1ZZW A;  3QCB A;  2NV5 A;  4RI4 A;  5KAB A;  2PA5 A;  5BUG A;  2CNI A;  3O3L A;  2QDC A;  2NZ6 A;  1U25 A;  3LJ8 A;  3S3H A;  1Q6T A;  2J16 A;  2CM2 A;  2QCJ A;  2BIJ A;  4D3R A;  2ESB A;  2CFV A;  2HCM A;  3V0J A;  4QAP A;  3GXH A;  4QUM A;  4OHH A;  1T4J A;  4YR8 B;  3GXG A;  4MBB A;  3RGO A;  1LYV A;  3M4U A;  3ZM1 A;  3BRH A;  3V0D A;  4OHE A;  1PA9 A;  1YPT A;  3RGQ A;  2AZR A;  3RZ2 A;  1YGU A;  3H2X A;  3QCF A;  5K9W A;  3BM8 A;  2I1Y A;  2I6M A;  2NLK A;  4BJO A;  3QCL A;  2I6I A;  4J51 A;  4R30 A;  3PS5 A;  2HY3 A;  3MOZ A;  1L8K A;  1X24 A;  1OEU A;  4R0T A;  1C87 A;  2CNG A;  4AZ1 A;  2I5X A;  2BGE A;  5M43 A;  4QBE A;  3V0H A;  1D5R A;  3D42 A;  3F9B A;  4KI9 A;  5KA3 A;  1PH0 A;  2PI7 A;  2Y96 A;  4ZRT A;  1ZCK A;  3V0E A;  3EU0 A;  4GS0 A;  1YFO A;  1GWZ A;  5KA0 A;  4RI5 A;  3QKQ A;  4IKC A;  2FH7 A;  4RKK A;  1U26 A;  2F71 A;  2B07 A;  5KAA A;  2F70 A;  2CJZ A;  3A5K A;  1FPZ A;  1OET A;  2RF6 A;  1LQF A;  3V0I A;  4KYR A;  5KA7 A;  2IMG A;  1XRI A;  4DGX A;  3U96 A;  1OHC A;  1I9S A;  4WU2 A;  2I42 A;  4JBC A;  5J8R A;  1C84 A;  3ZV2 A;  2ZN7 A;  4H1O A;  4D3P A;  1YZ4 A;  1SUG A;  1RPM A;  1V3A A;  2CMB A;  1R6H A;  2CM8 A;  3RO1 A;  1XBO A;  2I4H A;  1ZC0 A;  2C46 A;  2DXP A;  4Z6B A;  2H4G A;  1ONY A;  2PBN A;  1J4X A;  2Q05 A;  3QCH A;  4JNB A;  3O4T A;  4Y2E A;  3I36 A;  2WGP A;  1G4W R;  3QCE A;  5KA1 A;  2I4G A;  1C88 A;  3D1H A;  3SME A;  3D9C A;  5LXQ B;  3D1O A;  3EMU A;  1Q6M A;  5K23 A;  2C7S A;  1C86 A;  2M3V A;  2PT0 A;  2ZMM A;  2CNE A;  5KAC A;  3ZM2 A;  1EEN A;  1EEO A;  4ICZ A;  2H04 A;  4GFU A;  4OHI A;  3S4O A;  3QCJ A;  2OZ5 A;  5BX1 A;  1YGR A;  1YTW A;  2AHS A;  2A8B A;  5BZX A;  4JMJ A;  3EB1 A;  1GFY A;  1PXH A;  3ZMP A;  2B4O A;  1NO6 A;  1P15 A;  3MMJ A;  3O4S A;  2I3R A;  1U24 A;  2CMC A;  3QKP A;  4B04 A;  4GRZ A;  1OEO X;  2HNQ A;  2I4E A;  2PSZ A;  2Q47 A;  3B7O A;  3OLR A;  5EHR A;  3QCK A;  1OEM X;  1OHE A;  3F41 A;  4ZI4 A;  2F6T A;  4D3Q A;  2QCT A;  2B4P A;  2OOQ A;  4HRF A;  3I80 A;  1YWF A;  5K9V A;  2VEW A;  4HJP A;  4QUN A;  4RDD A;  1ONZ A;  4WU3 A;  4S0G A;  2HVL A;  2JJD A;  5BZZ A;  1G1F A;  1VHR A;  1Q6S A;  5MMZ B;  5K22 A;  4ZN5 A;  2GJT A;  3EAX A;  3F81 A;  3O5X A;  2NT7 A;  4H34 A;  3MOW A;  4BPC A;  1OHD A;  1Q6P A;  2Y2F A;  3O4U A;  3D44 A;  2VEV A;  3AWE A;  4NND A;  3QCG A;  4GE2 A;  1PYN A;  1C83 A;  4OHL A;  2HB1 A;  1G7F A;  5K25 A;  3ZM0 A;  1JLN A;  2VEU A;  1Q6J A;  3S4E A;  2BGD A;  2HXP A;  3QCD A;  4QAH A;  5IBS A;  4YAA A;  2HC2 A;  5KAD A;  1BZC A;  5KA8 A;  4PYH A;  1WAX A;  4WOH A;  5K24 A;  1PTY A;  2B4S A;  1YTS A;  2QBR A;  2B3O A;  2R0B A;  2J16 B;  2F6V A;  2CM3 A;  4GE5 A;  4DGP A;  1XXV A;  1NWE A;  2F6F A;  2I6P A;  3CWE A;  1JF7 A;  4OHD A;  4KYQ A;  3V0F A;  2QDP A;  2G6Z A;  1M3G A;  3N0A A;  2VEY A;  1Q1M A;  3OMH A;  2I6J A;  5AWX A;  3V0G A;  3AWF A;  5IBM A;  4NWF A;  1NWL A;  1G1H A;  1BZJ A;  2QDM A;  1YN9 A;  2CNF A;  4ERC A;  4GWF A;  1T48 A;  3S3K A;  2HNP A;  3F99 A;  1QXK A;  3CM3 A;  1MKP A;  4GFV A;  1PTU A;  1LAR A;  2B49 A;  2FJN A;  2BZL A;  1G7G A;  2QEP A;  3QCM A;  1FPR A;  5I6V A;  4GE6 A;  1XXP A;  1OES A;  4WTY A;  2CM7 A;  2CNH A;  2YDU A;  2NT2 A;  2BV5 A;  2G59 A;  3S3F A;  2H4V A;  2QBP A;  1Q6N A;  2GP0 A;  2F6Y A;  2HC1 A;  3QCI A;  2GWO A;  3EZZ A;  4NWG A;  5HDE A;  2F6W A;  2QBQ A;  2VEX A;  4RH9 A;  3QCN A;  2I3U A;  2CMA A;  3QCC A;  1A5Y A;  3BLT A;  3A5J A;  1AAX A;  1G4U S;  1PTV A;  2I75 A;  4JMK A;  4RH5 A; 
#chains in the Genus database with same CATH topology
 2P4D A;  5KA4 A;  4PVG A;  5KA2 A;  1OEV A;  3ZM3 A;  3SR9 A;  5GTJ A;  2P6X A;  1WRM A;  1KAK A;  2B4U A;  4RHG A;  2MBC A;  1C85 A;  4TVV A;  2F46 A;  1XM2 A;  2H4K A;  4NX8 A;  2E0T A;  2H03 A;  5KA9 A;  3D1Q A;  3F9A A;  1ECV A;  2I6O A;  1T49 A;  3AWG A;  3NME A;  2F6Z A;  3QCZ A;  1ZCL A;  2OUD A;  1I9T A;  4I8N A;  2NTA A;  2PQ5 A;  1PA1 A;  1NL9 A;  3BLU A;  3I7Z A;  2OC3 A;  1RXD A;  4QBW A;  2SHP A;  1PTT A;  1QZ0 A;  3ZMQ A;  4HJQ A;  2A3K A;  1NNY A;  4Y14 A;  5EHP A;  4NYH A;  1L8G A;  2H02 A;  1WCH A;  1I57 A;  1KAV A;  2XPC A;  1FQ1 A;  1BZH A;  2FJM A;  1YTN A;  1NZ7 A;  4R0S A;  2QBS A;  3S3E A;  4GRY A;  1G1G A;  2J17 A;  1FGS A;  1ZZW A;  3QCB A;  2NV5 A;  4RI4 A;  5KAB A;  2PA5 A;  5BUG A;  2CNI A;  2UUO A;  3O3L A;  2QDC A;  2NZ6 A;  1U25 A;  3LJ8 A;  4QF5 A;  3S3H A;  1Q6T A;  2J16 A;  2CM2 A;  2QCJ A;  2BIJ A;  4D3R A;  2ESB A;  2CFV A;  2HCM A;  3V0J A;  4QAP A;  3GXH A;  4C12 A;  4QUM A;  4OHH A;  5A5F A;  1T4J A;  4YR8 B;  2JFF A;  3GXG A;  4MBB A;  3RGO A;  1LYV A;  3M4U A;  3ZM1 A;  2GCA A;  3BRH A;  3V0D A;  4OHE A;  1PA9 A;  1YPT A;  3RGQ A;  2AZR A;  3RZ2 A;  1YGU A;  3H2X A;  3QCF A;  2WJP A;  3MVN A;  5K9W A;  3BM8 A;  2I1Y A;  2I6M A;  2NLK A;  4BJO A;  3QCL A;  2I6I A;  4J51 A;  4R30 A;  3PS5 A;  2HY3 A;  3MOZ A;  1L8K A;  1X24 A;  1OEU A;  4R0T A;  1C87 A;  2CNG A;  4AZ1 A;  2I5X A;  2BGE A;  5M43 A;  4QBE A;  3V0H A;  1D5R A;  3D42 A;  3F9B A;  4KI9 A;  5KA3 A;  1PH0 A;  2PI7 A;  2Y96 A;  3ZL8 A;  4ZRT A;  1ZCK A;  3V0E A;  3EU0 A;  1O5Z A;  4GS0 A;  1YFO A;  1GWZ A;  3UAG A;  5KA0 A;  4RI5 A;  3QKQ A;  4IKC A;  2FH7 A;  4RKK A;  1U26 A;  2F71 A;  2B07 A;  5KAA A;  2F70 A;  2CJZ A;  3A5K A;  1FPZ A;  1OET A;  2RF6 A;  1LQF A;  3V0I A;  4KYR A;  5KA7 A;  2IMG A;  1XRI A;  4DGX A;  3U96 A;  1OHC A;  1P3D A;  1I9S A;  1GQQ A;  2I42 A;  4WU2 A;  4JBC A;  5J8R A;  1C84 A;  2X5O A;  3ZV2 A;  2VOS A;  2ZN7 A;  4BUB A;  4H1O A;  4D3P A;  2VOR A;  1YZ4 A;  1SUG A;  1RPM A;  1V3A A;  2CMB A;  1R6H A;  2CM8 A;  1GG4 A;  3RO1 A;  1XBO A;  2I4H A;  3NRS A;  1ZC0 A;  2F00 A;  2C46 A;  2DXP A;  2GCB A;  4Z6B A;  2H4G A;  1ONY A;  2PBN A;  1J4X A;  4CVL A;  2Q05 A;  3QCH A;  4JNB A;  3O4T A;  4Y2E A;  2JFH A;  3I36 A;  2WGP A;  1G4W R;  3QCE A;  5KA1 A;  2I4G A;  1C88 A;  3D1H A;  3SME A;  3D9C A;  5LXQ B;  3D1O A;  3EMU A;  1Q6M A;  2Y1O A;  5K23 A;  2C7S A;  1C86 A;  2M3V A;  2PT0 A;  2ZMM A;  3LK7 A;  2CNE A;  5KAC A;  3ZM2 A;  1EEN A;  1EEO A;  2UUP A;  4ICZ A;  2H04 A;  4GFU A;  4OHI A;  3S4O A;  3QCJ A;  2OZ5 A;  5BX1 A;  1YGR A;  1YTW A;  2AHS A;  2A8B A;  5BZX A;  4JMJ A;  3EB1 A;  1GFY A;  1PXH A;  2AM2 A;  2GC6 A;  3ZMP A;  2B4O A;  1NO6 A;  1P15 A;  3MMJ A;  3O4S A;  2I3R A;  1U24 A;  2CMC A;  3QKP A;  4B04 A;  4GRZ A;  1OEO X;  2HNQ A;  2I4E A;  2PSZ A;  2Q47 A;  2WTZ A;  3B7O A;  3OLR A;  5EHR A;  3QCK A;  1OEM X;  1OHE A;  3F41 A;  4ZI4 A;  2F6T A;  1UAG A;  4D3Q A;  3PYZ A;  2QCT A;  2B4P A;  2OOQ A;  4HRF A;  3I80 A;  1YWF A;  5K9V A;  2VEW A;  4HJP A;  4QUN A;  4RDD A;  4UAG A;  1W7K A;  1E0D A;  1ONZ A;  4S0G A;  4WU3 A;  2JFG A;  2XJA A;  2HVL A;  1EEH A;  2JJD A;  5BZZ A;  4ZIY A;  1G1F A;  1VHR A;  1Q6S A;  5MMZ B;  5K22 A;  4ZN5 A;  2GJT A;  1J6U A;  3EAX A;  3F81 A;  3O5X A;  2NT7 A;  4H34 A;  3MOW A;  4BPC A;  2UAG A;  1OHD A;  1Q6P A;  2Y2F A;  4C13 A;  3O4U A;  3D44 A;  2VEV A;  3AWE A;  3ZM6 A;  4NND A;  3QCG A;  4GE2 A;  1PYN A;  1C83 A;  4OHL A;  2VTE A;  2HB1 A;  1G7F A;  5K25 A;  2Y66 A;  3ZM0 A;  1JLN A;  2VEU A;  1Q6J A;  1P31 A;  3S4E A;  2BGD A;  2HXP A;  3QCD A;  4QAH A;  5IBS A;  4YAA A;  2HC2 A;  5KAD A;  1BZC A;  5KA8 A;  4PYH A;  4CVK A;  1WAX A;  2GC5 A;  4WOH A;  5K24 A;  1PTY A;  2B4S A;  1YTS A;  2QBR A;  2B3O A;  1JBV A;  2R0B A;  5A5E A;  2J16 B;  2F6V A;  2CM3 A;  1E8C A;  4GE5 A;  4DGP A;  1XXV A;  1NWE A;  1W78 A;  2F6F A;  2I6P A;  3CWE A;  1JF7 A;  4OHD A;  4KYQ A;  3V0F A;  2QDP A;  2Y67 A;  2G6Z A;  1M3G A;  3N0A A;  2VEY A;  1Q1M A;  3OMH A;  2I6J A;  5AWX A;  3V0G A;  1JBW A;  3AWF A;  5IBM A;  4NWF A;  1NWL A;  1G1H A;  3N2A A;  1BZJ A;  2QDM A;  1GQY A;  1YN9 A;  2CNF A;  4ERC A;  4GWF A;  1T48 A;  3S3K A;  2HNP A;  3F99 A;  1QXK A;  3CM3 A;  1MKP A;  4GFV A;  3ZM5 A;  4CVM A;  1PTU A;  1LAR A;  2B49 A;  2FJN A;  2BZL A;  1G7G A;  2QEP A;  3QCM A;  4QDI A;  1FPR A;  2VTD A;  4GE6 A;  5I6V A;  1XXP A;  1OES A;  2Y68 A;  4WTY A;  2CM7 A;  2CNH A;  2YDU A;  2NT2 A;  2BV5 A;  2G59 A;  3S3F A;  2H4V A;  2QBP A;  1Q6N A;  2GP0 A;  4BUC A;  4HV4 A;  2F6Y A;  2HC1 A;  3QCI A;  2GWO A;  3EZZ A;  4NWG A;  5HDE A;  2F6W A;  2QBQ A;  2VEX A;  4RH9 A;  3QCN A;  2I3U A;  2CMA A;  2AM1 A;  3QCC A;  1A5Y A;  3BLT A;  3HN7 A;  3A5J A;  1AAX A;  1G4U S;  1PTV A;  2I75 A;  4JMK A;  4RH5 A; 
#chains in the Genus database with same CATH homology
 2P4D A;  5KA4 A;  4PVG A;  5KA2 A;  1OEV A;  3ZM3 A;  3SR9 A;  5GTJ A;  2P6X A;  1WRM A;  1KAK A;  2B4U A;  4RHG A;  2MBC A;  1C85 A;  4TVV A;  2F46 A;  1XM2 A;  2H4K A;  4NX8 A;  2E0T A;  2H03 A;  5KA9 A;  3D1Q A;  3F9A A;  1ECV A;  2I6O A;  1T49 A;  3AWG A;  3NME A;  2F6Z A;  1ZCL A;  2OUD A;  1I9T A;  4I8N A;  2NTA A;  2PQ5 A;  1PA1 A;  1NL9 A;  3BLU A;  3I7Z A;  2OC3 A;  1RXD A;  4QBW A;  2SHP A;  1PTT A;  1QZ0 A;  3ZMQ A;  4HJQ A;  2A3K A;  1NNY A;  4Y14 A;  5EHP A;  4NYH A;  1L8G A;  2H02 A;  1WCH A;  1I57 A;  1KAV A;  1FQ1 A;  1BZH A;  2FJM A;  1YTN A;  1NZ7 A;  4R0S A;  2QBS A;  3S3E A;  4GRY A;  1G1G A;  2J17 A;  1ZZW A;  3QCB A;  2NV5 A;  4RI4 A;  5KAB A;  2PA5 A;  5BUG A;  2CNI A;  3O3L A;  2QDC A;  2NZ6 A;  1U25 A;  3LJ8 A;  3S3H A;  1Q6T A;  2J16 A;  2CM2 A;  2QCJ A;  2BIJ A;  4D3R A;  2ESB A;  2CFV A;  2HCM A;  3V0J A;  4QAP A;  3GXH A;  4QUM A;  4OHH A;  1T4J A;  4YR8 B;  3GXG A;  4MBB A;  3RGO A;  1LYV A;  3M4U A;  3ZM1 A;  3BRH A;  3V0D A;  4OHE A;  1PA9 A;  1YPT A;  3RGQ A;  2AZR A;  3RZ2 A;  1YGU A;  3H2X A;  3QCF A;  5K9W A;  3BM8 A;  2I1Y A;  2I6M A;  2NLK A;  4BJO A;  3QCL A;  2I6I A;  4J51 A;  4R30 A;  3PS5 A;  2HY3 A;  3MOZ A;  1L8K A;  1X24 A;  1OEU A;  4R0T A;  1C87 A;  2CNG A;  4AZ1 A;  2I5X A;  2BGE A;  5M43 A;  4QBE A;  3V0H A;  1D5R A;  3D42 A;  3F9B A;  4KI9 A;  5KA3 A;  1PH0 A;  2PI7 A;  2Y96 A;  4ZRT A;  1ZCK A;  3V0E A;  3EU0 A;  4GS0 A;  1YFO A;  1GWZ A;  5KA0 A;  4RI5 A;  3QKQ A;  4IKC A;  2FH7 A;  4RKK A;  1U26 A;  2F71 A;  2B07 A;  5KAA A;  2F70 A;  2CJZ A;  3A5K A;  1FPZ A;  1OET A;  2RF6 A;  1LQF A;  3V0I A;  4KYR A;  5KA7 A;  2IMG A;  1XRI A;  4DGX A;  3U96 A;  1OHC A;  1I9S A;  4WU2 A;  2I42 A;  4JBC A;  5J8R A;  1C84 A;  3ZV2 A;  2ZN7 A;  4H1O A;  4D3P A;  1YZ4 A;  1SUG A;  1RPM A;  1V3A A;  2CMB A;  1R6H A;  2CM8 A;  3RO1 A;  1XBO A;  2I4H A;  1ZC0 A;  2C46 A;  2DXP A;  4Z6B A;  2H4G A;  1ONY A;  2PBN A;  1J4X A;  2Q05 A;  3QCH A;  4JNB A;  3O4T A;  4Y2E A;  3I36 A;  2WGP A;  1G4W R;  3QCE A;  5KA1 A;  2I4G A;  1C88 A;  3D1H A;  3SME A;  3D9C A;  5LXQ B;  3D1O A;  3EMU A;  1Q6M A;  5K23 A;  2C7S A;  1C86 A;  2M3V A;  2PT0 A;  2ZMM A;  2CNE A;  5KAC A;  3ZM2 A;  1EEN A;  1EEO A;  4ICZ A;  2H04 A;  4GFU A;  4OHI A;  3S4O A;  3QCJ A;  2OZ5 A;  5BX1 A;  1YGR A;  1YTW A;  2AHS A;  2A8B A;  5BZX A;  4JMJ A;  3EB1 A;  1GFY A;  1PXH A;  3ZMP A;  2B4O A;  1NO6 A;  1P15 A;  3MMJ A;  3O4S A;  2I3R A;  1U24 A;  2CMC A;  3QKP A;  4B04 A;  4GRZ A;  1OEO X;  2HNQ A;  2I4E A;  2PSZ A;  2Q47 A;  3B7O A;  3OLR A;  5EHR A;  3QCK A;  1OEM X;  1OHE A;  3F41 A;  4ZI4 A;  2F6T A;  4D3Q A;  2QCT A;  2B4P A;  2OOQ A;  4HRF A;  3I80 A;  1YWF A;  5K9V A;  2VEW A;  4HJP A;  4QUN A;  4RDD A;  1ONZ A;  4WU3 A;  4S0G A;  2HVL A;  2JJD A;  5BZZ A;  1G1F A;  1VHR A;  1Q6S A;  5MMZ B;  5K22 A;  4ZN5 A;  2GJT A;  3EAX A;  3F81 A;  3O5X A;  2NT7 A;  4H34 A;  3MOW A;  4BPC A;  1OHD A;  1Q6P A;  2Y2F A;  3O4U A;  3D44 A;  2VEV A;  3AWE A;  4NND A;  3QCG A;  4GE2 A;  1PYN A;  1C83 A;  4OHL A;  2HB1 A;  1G7F A;  5K25 A;  3ZM0 A;  1JLN A;  2VEU A;  1Q6J A;  3S4E A;  2BGD A;  2HXP A;  3QCD A;  4QAH A;  5IBS A;  4YAA A;  2HC2 A;  5KAD A;  1BZC A;  5KA8 A;  4PYH A;  1WAX A;  4WOH A;  5K24 A;  1PTY A;  2B4S A;  1YTS A;  2QBR A;  2B3O A;  2R0B A;  2J16 B;  2F6V A;  2CM3 A;  4GE5 A;  4DGP A;  1XXV A;  1NWE A;  2F6F A;  2I6P A;  3CWE A;  1JF7 A;  4OHD A;  4KYQ A;  3V0F A;  2QDP A;  2G6Z A;  1M3G A;  3N0A A;  2VEY A;  1Q1M A;  3OMH A;  2I6J A;  5AWX A;  3V0G A;  3AWF A;  5IBM A;  4NWF A;  1NWL A;  1G1H A;  1BZJ A;  2QDM A;  1YN9 A;  2CNF A;  4ERC A;  4GWF A;  1T48 A;  3S3K A;  2HNP A;  3F99 A;  1QXK A;  3CM3 A;  1MKP A;  4GFV A;  1PTU A;  1LAR A;  2B49 A;  2FJN A;  2BZL A;  1G7G A;  2QEP A;  3QCM A;  1FPR A;  5I6V A;  4GE6 A;  1XXP A;  1OES A;  4WTY A;  2CM7 A;  2CNH A;  2YDU A;  2NT2 A;  2BV5 A;  2G59 A;  3S3F A;  2H4V A;  2QBP A;  1Q6N A;  2GP0 A;  2F6Y A;  2HC1 A;  3QCI A;  2GWO A;  3EZZ A;  4NWG A;  5HDE A;  2F6W A;  2QBQ A;  2VEX A;  4RH9 A;  3QCN A;  2I3U A;  2CMA A;  3QCC A;  1A5Y A;  3BLT A;  3A5J A;  1AAX A;  1G4U S;  1PTV A;  2I75 A;  4JMK A;  4RH5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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