1CA1A

Alpha-toxin from clostridium perfringens
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
370
structure length
370
Chain Sequence
b'WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFSKDNSWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTVGCKTNEDFYADILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFPDAYKPENIKVIANGKVVVDKDINEWISGNSTYNIK'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ALPHA-TOXIN
publication title Structure of the key toxin in gas gangrene.
pubmed doi rcsb
source organism Clostridium perfringens
molecule tags Hydrolase
total genus 137
structure length 370
sequence length 370
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 1998-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1ca1A01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1ca1A02
2FNQA 1GYGA 5EEOA 2FFZA 5FBBA 4CXOA 3BNCA 1IK3A 2WXUA 2WXTA 5FBDA 4NREA 5FBFA 3FG3A 4CXPA 3V99A 1P6DA 1AK0A 1LPAB 1FGQA 4CWMA 1AH7A 1HPLA 2HUCA 4WHAA 2IUKA 1W52X 1FGMA 1ROVA 3FG1A 3FG4A 2PVSA 4DJ4A 3O8YA 3BNBA 2PPLA 3W52A 4CXVA 4JDGA 1KHOA 1LNHA 3CWZB 1ETHA 2SBLA 1CA1A 1OLPA 4QWTA 1QMDA 1QM6A 2OXEA 1P6EA 1NO3A 3V98A 3BNEA 1BU8A 1FGRA 5FBGA 1FGOA 4WFOA 3PZWA 1F8NA 1LPBB 3SNGA 5FBAA 1FGTA 1JNQA 2IUJA 3VF1A 1Y4KA 1LOXA 2WY6A 1HU9A 1RRLA 2FGNA 3BNDA 5FB9A 5FBCA 1RRHA 2P0MA 3V92A 1GPLA 1P5XA 1YGEA 1N8SA 1N8QA 1RP1A
chains in the Genus database with same CATH superfamily
2FNQA 1GYGA 5EEOA 2LGEA 2FFZA 5FBBA 2KXVA 4CXOA 3BNCA 1IK3A 2WXUA 2QNGA 2LG7A 2WXTA 5FBDA 4NREA 5FBFA 3FG3A 4CXPA 3V99A 4QEYA 1P6DA 1AK0A 1LPAB 1FGQA 4CWMA 1AH7A 1HPLA 2HUCA 4WHAA 2IUKA 1W52X 1FGMA 3U6GA 1ROVA 3FG1A 3FG4A 2PVSA 4DJ4A 3O8YA 3BNBA 2XHHA 2PPLA 3W52A 4CXVA 4JDGA 1KHOA 1LNHA 3CWZB 1ETHA 2SBLA 1CA1A 1OLPA 4QWTA 1QMDA 1QM6A 2OXEA 1P6EA 1NO3A 3V98A 3IBZA 3BNEA 1BU8A 2XHJA 1FGRA 5FBGA 1FGOA 4WFOA 3PZWA 1F8NA 1LPBB 2KXTA 3SNGA 5FBAA 1FGTA 1JNQA 2IUJA 3VF1A 1Y4KA 1LOXA 2WY6A 1HU9A 1RRLA 2FGNA 2XFEA 3BNDA 5FB9A 5FBCA 1RRHA 2QZ7A 2XFDA 2P0MA 3V92A 2LRGA 1GPLA 1P5XA 1YGEA 1N8SA 1N8QA 1RP1A
chains in the Genus database with same CATH topology
2FNQA 1GYGA 5EEOA 2FFZA 5FBBA 4CXOA 3BNCA 1IK3A 2WXUA 2WXTA 5FBDA 4NREA 5FBFA 3FG3A 4CXPA 3V99A 1P6DA 1AK0A 1LPAB 1FGQA 4CWMA 1AH7A 1HPLA 2HUCA 4WHAA 2IUKA 1W52X 1FGMA 1ROVA 3FG1A 3FG4A 2PVSA 4DJ4A 3O8YA 3BNBA 2PPLA 3W52A 4CXVA 4JDGA 1KHOA 1LNHA 3CWZB 1ETHA 2SBLA 1CA1A 1OLPA 4QWTA 1QMDA 1QM6A 2OXEA 1P6EA 1NO3A 3V98A 3BNEA 1BU8A 1FGRA 5FBGA 1FGOA 4WFOA 3PZWA 1F8NA 1LPBB 3SNGA 5FBAA 1FGTA 1JNQA 2IUJA 3VF1A 1Y4KA 1LOXA 2WY6A 1HU9A 1RRLA 2FGNA 3BNDA 5FB9A 5FBCA 1RRHA 2P0MA 3V92A 1GPLA 1P5XA 1YGEA 1N8SA 1N8QA 1RP1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FNQ A;  1GYG A;  5EEO A;  2FFZ A;  5FBB A;  4CXO A;  3BNC A;  1IK3 A;  2WXU A;  2WXT A;  5FBD A;  4NRE A;  5FBF A;  3FG3 A;  4CXP A;  3V99 A;  1P6D A;  1AK0 A;  1LPA B;  1FGQ A;  4CWM A;  1AH7 A;  1HPL A;  2HUC A;  4WHA A;  2IUK A;  1W52 X;  1FGM A;  1ROV A;  3FG1 A;  3FG4 A;  2PVS A;  4DJ4 A;  3O8Y A;  3BNB A;  2PPL A;  3W52 A;  4CXV A;  4JDG A;  1KHO A;  1LNH A;  3CWZ B;  1ETH A;  2SBL A;  1CA1 A;  1OLP A;  4QWT A;  1QMD A;  1QM6 A;  2OXE A;  1P6E A;  1NO3 A;  3V98 A;  3BNE A;  1BU8 A;  1FGR A;  5FBG A;  1FGO A;  4WFO A;  3PZW A;  1F8N A;  1LPB B;  3SNG A;  5FBA A;  1FGT A;  1JNQ A;  2IUJ A;  3VF1 A;  1Y4K A;  1LOX A;  2WY6 A;  1HU9 A;  1RRL A;  2FGN A;  3BND A;  5FB9 A;  5FBC A;  1RRH A;  2P0M A;  3V92 A;  1GPL A;  1P5X A;  1YGE A;  1N8S A;  1N8Q A;  1RP1 A; 
#chains in the Genus database with same CATH topology
 2FNQ A;  1GYG A;  5EEO A;  2LGE A;  2FFZ A;  5FBB A;  2KXV A;  4CXO A;  3BNC A;  1IK3 A;  2WXU A;  2QNG A;  2LG7 A;  2WXT A;  5FBD A;  4NRE A;  5FBF A;  3FG3 A;  4CXP A;  3V99 A;  4QEY A;  1P6D A;  1AK0 A;  1LPA B;  1FGQ A;  4CWM A;  1AH7 A;  1HPL A;  2HUC A;  4WHA A;  2IUK A;  1W52 X;  1FGM A;  3U6G A;  1ROV A;  3FG1 A;  3FG4 A;  2PVS A;  4DJ4 A;  3O8Y A;  3BNB A;  2XHH A;  2PPL A;  3W52 A;  4CXV A;  4JDG A;  1KHO A;  1LNH A;  3CWZ B;  1ETH A;  2SBL A;  1CA1 A;  1OLP A;  4QWT A;  1QMD A;  1QM6 A;  2OXE A;  1P6E A;  1NO3 A;  3V98 A;  3IBZ A;  3BNE A;  1BU8 A;  2XHJ A;  1FGR A;  5FBG A;  1FGO A;  4WFO A;  3PZW A;  1F8N A;  1LPB B;  2KXT A;  3SNG A;  5FBA A;  1FGT A;  1JNQ A;  2IUJ A;  3VF1 A;  1Y4K A;  1LOX A;  2WY6 A;  1HU9 A;  1RRL A;  2FGN A;  2XFE A;  3BND A;  5FB9 A;  5FBC A;  1RRH A;  2QZ7 A;  2XFD A;  2P0M A;  3V92 A;  2LRG A;  1GPL A;  1P5X A;  1YGE A;  1N8S A;  1N8Q A;  1RP1 A; 
#chains in the Genus database with same CATH homology
 2FNQ A;  1GYG A;  5EEO A;  2FFZ A;  5FBB A;  4CXO A;  3BNC A;  1IK3 A;  2WXU A;  2WXT A;  5FBD A;  4NRE A;  5FBF A;  3FG3 A;  4CXP A;  3V99 A;  1P6D A;  1AK0 A;  1LPA B;  1FGQ A;  4CWM A;  1AH7 A;  1HPL A;  2HUC A;  4WHA A;  2IUK A;  1W52 X;  1FGM A;  1ROV A;  3FG1 A;  3FG4 A;  2PVS A;  4DJ4 A;  3O8Y A;  3BNB A;  2PPL A;  3W52 A;  4CXV A;  4JDG A;  1KHO A;  1LNH A;  3CWZ B;  1ETH A;  2SBL A;  1CA1 A;  1OLP A;  4QWT A;  1QMD A;  1QM6 A;  2OXE A;  1P6E A;  1NO3 A;  3V98 A;  3BNE A;  1BU8 A;  1FGR A;  5FBG A;  1FGO A;  4WFO A;  3PZW A;  1F8N A;  1LPB B;  3SNG A;  5FBA A;  1FGT A;  1JNQ A;  2IUJ A;  3VF1 A;  1Y4K A;  1LOX A;  2WY6 A;  1HU9 A;  1RRL A;  2FGN A;  3BND A;  5FB9 A;  5FBC A;  1RRH A;  2P0M A;  3V92 A;  1GPL A;  1P5X A;  1YGE A;  1N8S A;  1N8Q A;  1RP1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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