1CHMA

Enzymatic mechanism of creatine amidinohydrolase as deduced from crystal structures
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
401
structure length
401
Chain Sequence
QMPKTLRIRNGDKVRSTFSAQEYANRQARLRAHLAAENIDAAIFTSYHNINYYSDFLYCSFGRPYALVVTEDDVISISANIDGGQPWRRTVGTDNIVYTDWQRDNYFAAIQQALPKARRIGIEHDHLNLQNRDKLAARYPDAELVDVAAACMRMRMIKSAEEHVMIRHGARIADIGGAAVVEALGDQVPEYEVALHATQAMVRAIADTFEDVELMDTWTWFQSGINTDGAHNPVTTRKVNKGDILSLNCFPMIAGYYTALERTLFLDHCSDDHLRLWQVNVEVHEAGLKLIKPGARCSDIARELNEIFLKHDVLQYRTFGYGHSFGTLSHYYGREAGLELREDIDTVLEPGMVVSMEPMIMLPEGLPGAGGYREHDILIVNENGAENITKFPYGPEKNIIR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Enzymatic mechanism of creatine amidinohydrolase as deduced from crystal structures.
pubmed doi rcsb
source organism Pseudomonas putida
molecule tags Creatinase
molecule keywords CREATINE AMIDINOHYDROLASE
total genus 143
structure length 401
sequence length 401
chains with identical sequence B
ec nomenclature ec 3.5.3.3: Creatinase.
pdb deposition date 1993-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1chmA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1chmA02
5CNXA 2BH3A 2BN7A 4RZZA 4A6WA 2B3HA 2OAZA 2GG9A 2HOWA 1QXWA 3OOOA 4A6VA 1N51A 1WBQA 4U76A 3TAVA 2BWWA 2GU5A 1Y1NA 5JHUA 2GA2A 4ZWUA 4ZWPA 2Q94A 1YW9A 3O5VA 2GG3A 1XGSA 2GU6A 4RGZ1 2BB7A 2GU4A 1YW7A 3BIQA 4B28A 4U6EA 4FO8A 4KM3A 1QXZA 4IKTA 1WLRA 2BWYA 2BWTA 4U6ZA 2Q8KA 2B3KA 4Z7MA 3MX6A 2GG7A 4IECA 4EGEA 4IF7A 1C21A 5CDLA 2V3YA 2EVCA 3OVKA 4S2RP 2ZSGA 2Q92A 3QOCA 2GG2A 3D27A 4FLJA 3PKEA 1W2MA 2BHAA 4S00A 2B3LA 1XGOA 4S01A 1R58A 2GG5A 1KP0A 2GG8A 2G6PA 2GGBA 4HXXA 1R5HA 3BIPA 3IU9A 1QXYA 2EA2A 2GU7A 2DFIA 3PKDA 4FLLA 3IU8A 2GG0A 4JUQA 1C27A 4U6CA 2BHDA 2NQ6A 1PV9A 4IDYA 1WL6A 4U73A 3PKBA 5JFRA 3CTZA 2BWXA 2P98A 3MATA 4OOKA 3PKAA 1JAWA 3L7GA 2P9AA 2BWVA 1QZYA 3FMQA 4U6JA 2NQ7A 1MATA 3MR1A 3FM3A 2BWSA 5E5BA 1BN5A 2V6CA 5CLSA 1WN1A 2GTXA 4RZYA 2ADUA 5FCFA 1O0XA 1XGNA 1YW8A 1BOAA 5JI6A 4IU6A 1R5GA 4U75A 4U69A 5CE6A 3PKCA 4ZNGA 3S6BA 1YJ3A 1KQ0A 4FUKA 4S2TP 1WL9A 1C24A 2BHBA 4FO7A 2GZ5A 4IKRA 4R60A 1YVMA 2EA4A 3L24A 4IKSA 4IKUA 2P99A 1B59A 2BHCA 5FCHA 4PV4A 2V3ZA 2MATA 1KQ9A 2EVMA 1XGMA 4IPAA 4FLIA 3BITA 4QR8A 4PNCA 4FKCA 5CDVA 1C23A 5D6EA 2Q95A 1W7VA 1M35A 1XNZA 5D6FA 4MATA 4U1BA 1B6AA 1WKMA 2Q96A 3IL0A 3RVAA 3TB5A 1A16A 3CB5A 3I7MA 3IG4A 4ZWOA 1CHMA 3PEBA 3PN9A 3IU7A 4FLKA 4U71A 2Q93A 2OKNA 2V3XA 3FMRA 2EVOA 4U70A 2IW2A 1WY2A 2BWUA 3Q6DA 5CDEA 2GGCA 3RORA 4U6WA 1C22A 5E2CA 3CB6A 5CIKA
chains in the Genus database with same CATH superfamily
5CNXA 2BH3A 2BN7A 4RZZA 4A6WA 2B3HA 2OAZA 2GG9A 2HOWA 1QXWA 3OOOA 4A6VA 1N51A 1WBQA 4U76A 3TAVA 2BWWA 2GU5A 1Y1NA 5JHUA 2GA2A 4ZWUA 4ZWPA 2Q94A 1YW9A 3O5VA 2GG3A 1XGSA 2GU6A 4RGZ1 2BB7A 2GU4A 1YW7A 3BIQA 4B28A 4U6EA 4FO8A 4KM3A 1QXZA 4IKTA 1WLRA 2BWYA 2BWTA 4U6ZA 2Q8KA 2B3KA 4Z7MA 3MX6A 2GG7A 4IECA 4EGEA 4IF7A 1C21A 5CDLA 2V3YA 2EVCA 3OVKA 4S2RP 2ZSGA 2Q92A 3QOCA 2GG2A 3D27A 4FLJA 3PKEA 1W2MA 2BHAA 4S00A 2B3LA 1XGOA 4S01A 1R58A 2GG5A 1KP0A 2GG8A 2G6PA 2GGBA 4HXXA 1R5HA 3BIPA 3IU9A 1QXYA 2EA2A 2GU7A 2DFIA 3PKDA 4FLLA 3IU8A 2GG0A 4JUQA 1C27A 4U6CA 2BHDA 2NQ6A 1PV9A 4IDYA 1WL6A 4U73A 3PKBA 5JFRA 3CTZA 2BWXA 2P98A 3MATA 4OOKA 3PKAA 1JAWA 3L7GA 2P9AA 2BWVA 1QZYA 3FMQA 4U6JA 2NQ7A 1MATA 3MR1A 3FM3A 2BWSA 5E5BA 1BN5A 2V6CA 5CLSA 1WN1A 2GTXA 4RZYA 2ADUA 5FCFA 1O0XA 1XGNA 1YW8A 1BOAA 5JI6A 4IU6A 1R5GA 4U75A 4U69A 5CE6A 3PKCA 4ZNGA 3S6BA 1YJ3A 1KQ0A 4FUKA 4S2TP 1WL9A 1C24A 2BHBA 4FO7A 2GZ5A 4IKRA 4R60A 1YVMA 2EA4A 3L24A 4IKSA 4IKUA 2P99A 1B59A 2BHCA 5FCHA 4PV4A 2V3ZA 2MATA 1KQ9A 2EVMA 1XGMA 4IPAA 4FLIA 3BITA 4QR8A 4PNCA 4FKCA 5CDVA 1C23A 5D6EA 2Q95A 1W7VA 1M35A 1XNZA 5D6FA 4MATA 4U1BA 1B6AA 1WKMA 2Q96A 3IL0A 3RVAA 3TB5A 1A16A 3CB5A 3I7MA 3IG4A 4ZWOA 1CHMA 3PEBA 3PN9A 3IU7A 4FLKA 4U71A 2Q93A 2OKNA 2V3XA 3FMRA 2EVOA 4U70A 2IW2A 1WY2A 2BWUA 3Q6DA 5CDEA 2GGCA 3RORA 4U6WA 1C22A 5E2CA 3CB6A 5CIKA
chains in the Genus database with same CATH topology
5CNXA 2BH3A 2BN7A 4RZZA 4A6WA 2B3HA 2OAZA 2GG9A 2HOWA 1QXWA 3OOOA 4A6VA 1N51A 1WBQA 4U76A 3TAVA 2BWWA 2GU5A 1Y1NA 5JHUA 2GA2A 4ZWUA 4ZWPA 2Q94A 1YW9A 3O5VA 2GG3A 1XGSA 2GU6A 4RGZ1 2BB7A 2GU4A 1YW7A 3BIQA 4B28A 4U6EA 4FO8A 4KM3A 1QXZA 4IKTA 1WLRA 2BWYA 2BWTA 4U6ZA 2Q8KA 2B3KA 4Z7MA 3MX6A 2GG7A 4IECA 4EGEA 4IF7A 1C21A 5CDLA 2V3YA 2EVCA 3OVKA 4S2RP 2ZSGA 2Q92A 3QOCA 2GG2A 3D27A 4FLJA 3PKEA 1W2MA 2BHAA 4S00A 2B3LA 1XGOA 4S01A 1R58A 2GG5A 1KP0A 2GG8A 2G6PA 2GGBA 4HXXA 1R5HA 3BIPA 3IU9A 1QXYA 2EA2A 2GU7A 2DFIA 3PKDA 4FLLA 3IU8A 2GG0A 4JUQA 1C27A 4U6CA 2BHDA 2NQ6A 1PV9A 4IDYA 1WL6A 4U73A 3PKBA 5JFRA 3CTZA 2BWXA 2P98A 3MATA 4OOKA 3PKAA 1JAWA 3L7GA 2P9AA 2BWVA 1QZYA 3FMQA 4U6JA 2NQ7A 1MATA 3MR1A 3FM3A 2BWSA 5E5BA 1BN5A 2V6CA 5CLSA 1WN1A 2GTXA 4RZYA 2ADUA 5FCFA 1O0XA 1XGNA 1YW8A 1BOAA 5JI6A 4IU6A 1R5GA 4U75A 4U69A 5CE6A 3PKCA 4ZNGA 3S6BA 1YJ3A 1KQ0A 4FUKA 4S2TP 1WL9A 1C24A 2BHBA 4FO7A 2GZ5A 4IKRA 4R60A 1YVMA 2EA4A 3L24A 4IKSA 4IKUA 2P99A 1B59A 2BHCA 5FCHA 4PV4A 2V3ZA 2MATA 1KQ9A 2EVMA 1XGMA 4IPAA 4FLIA 3BITA 4QR8A 4PNCA 4FKCA 5CDVA 1C23A 5D6EA 2Q95A 1W7VA 1M35A 1XNZA 5D6FA 4MATA 4U1BA 1B6AA 1WKMA 2Q96A 3IL0A 3RVAA 3TB5A 1A16A 3CB5A 3I7MA 3IG4A 4ZWOA 1CHMA 3PEBA 3PN9A 3IU7A 4FLKA 4U71A 2Q93A 2OKNA 2V3XA 3FMRA 2EVOA 4U70A 2IW2A 1WY2A 2BWUA 3Q6DA 5CDEA 2GGCA 3RORA 4U6WA 1C22A 5E2CA 3CB6A 5CIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CNX A;  2BH3 A;  2BN7 A;  4RZZ A;  4A6W A;  2B3H A;  2OAZ A;  2GG9 A;  2HOW A;  1QXW A;  3OOO A;  4A6V A;  1N51 A;  1WBQ A;  4U76 A;  3TAV A;  2BWW A;  2GU5 A;  1Y1N A;  5JHU A;  2GA2 A;  4ZWU A;  4ZWP A;  2Q94 A;  1YW9 A;  3O5V A;  2GG3 A;  1XGS A;  2GU6 A;  4RGZ 1;  2BB7 A;  2GU4 A;  1YW7 A;  3BIQ A;  4B28 A;  4U6E A;  4FO8 A;  4KM3 A;  1QXZ A;  4IKT A;  1WLR A;  2BWY A;  2BWT A;  4U6Z A;  2Q8K A;  2B3K A;  4Z7M A;  3MX6 A;  2GG7 A;  4IEC A;  4EGE A;  4IF7 A;  1C21 A;  5CDL A;  2V3Y A;  2EVC A;  3OVK A;  4S2R P;  2ZSG A;  2Q92 A;  3QOC A;  2GG2 A;  3D27 A;  4FLJ A;  3PKE A;  1W2M A;  2BHA A;  4S00 A;  2B3L A;  1XGO A;  4S01 A;  1R58 A;  2GG5 A;  1KP0 A;  2GG8 A;  2G6P A;  2GGB A;  4HXX A;  1R5H A;  3BIP A;  3IU9 A;  1QXY A;  2EA2 A;  2GU7 A;  2DFI A;  3PKD A;  4FLL A;  3IU8 A;  2GG0 A;  4JUQ A;  1C27 A;  4U6C A;  2BHD A;  2NQ6 A;  1PV9 A;  4IDY A;  1WL6 A;  4U73 A;  3PKB A;  5JFR A;  3CTZ A;  2BWX A;  2P98 A;  3MAT A;  4OOK A;  3PKA A;  1JAW A;  3L7G A;  2P9A A;  2BWV A;  1QZY A;  3FMQ A;  4U6J A;  2NQ7 A;  1MAT A;  3MR1 A;  3FM3 A;  2BWS A;  5E5B A;  1BN5 A;  2V6C A;  5CLS A;  1WN1 A;  2GTX A;  4RZY A;  2ADU A;  5FCF A;  1O0X A;  1XGN A;  1YW8 A;  1BOA A;  5JI6 A;  4IU6 A;  1R5G A;  4U75 A;  4U69 A;  5CE6 A;  3PKC A;  4ZNG A;  3S6B A;  1YJ3 A;  1KQ0 A;  4FUK A;  4S2T P;  1WL9 A;  1C24 A;  2BHB A;  4FO7 A;  2GZ5 A;  4IKR A;  4R60 A;  1YVM A;  2EA4 A;  3L24 A;  4IKS A;  4IKU A;  2P99 A;  1B59 A;  2BHC A;  5FCH A;  4PV4 A;  2V3Z A;  2MAT A;  1KQ9 A;  2EVM A;  1XGM A;  4IPA A;  4FLI A;  3BIT A;  4QR8 A;  4PNC A;  4FKC A;  5CDV A;  1C23 A;  5D6E A;  2Q95 A;  1W7V A;  1M35 A;  1XNZ A;  5D6F A;  4MAT A;  4U1B A;  1B6A A;  1WKM A;  2Q96 A;  3IL0 A;  3RVA A;  3TB5 A;  1A16 A;  3CB5 A;  3I7M A;  3IG4 A;  4ZWO A;  1CHM A;  3PEB A;  3PN9 A;  3IU7 A;  4FLK A;  4U71 A;  2Q93 A;  2OKN A;  2V3X A;  3FMR A;  2EVO A;  4U70 A;  2IW2 A;  1WY2 A;  2BWU A;  3Q6D A;  5CDE A;  2GGC A;  3ROR A;  4U6W A;  1C22 A;  5E2C A;  3CB6 A;  5CIK A; 
#chains in the Genus database with same CATH topology
 5CNX A;  2BH3 A;  2BN7 A;  4RZZ A;  4A6W A;  2B3H A;  2OAZ A;  2GG9 A;  2HOW A;  1QXW A;  3OOO A;  4A6V A;  1N51 A;  1WBQ A;  4U76 A;  3TAV A;  2BWW A;  2GU5 A;  1Y1N A;  5JHU A;  2GA2 A;  4ZWU A;  4ZWP A;  2Q94 A;  1YW9 A;  3O5V A;  2GG3 A;  1XGS A;  2GU6 A;  4RGZ 1;  2BB7 A;  2GU4 A;  1YW7 A;  3BIQ A;  4B28 A;  4U6E A;  4FO8 A;  4KM3 A;  1QXZ A;  4IKT A;  1WLR A;  2BWY A;  2BWT A;  4U6Z A;  2Q8K A;  2B3K A;  4Z7M A;  3MX6 A;  2GG7 A;  4IEC A;  4EGE A;  4IF7 A;  1C21 A;  5CDL A;  2V3Y A;  2EVC A;  3OVK A;  4S2R P;  2ZSG A;  2Q92 A;  3QOC A;  2GG2 A;  3D27 A;  4FLJ A;  3PKE A;  1W2M A;  2BHA A;  4S00 A;  2B3L A;  1XGO A;  4S01 A;  1R58 A;  2GG5 A;  1KP0 A;  2GG8 A;  2G6P A;  2GGB A;  4HXX A;  1R5H A;  3BIP A;  3IU9 A;  1QXY A;  2EA2 A;  2GU7 A;  2DFI A;  3PKD A;  4FLL A;  3IU8 A;  2GG0 A;  4JUQ A;  1C27 A;  4U6C A;  2BHD A;  2NQ6 A;  1PV9 A;  4IDY A;  1WL6 A;  4U73 A;  3PKB A;  5JFR A;  3CTZ A;  2BWX A;  2P98 A;  3MAT A;  4OOK A;  3PKA A;  1JAW A;  3L7G A;  2P9A A;  2BWV A;  1QZY A;  3FMQ A;  4U6J A;  2NQ7 A;  1MAT A;  3MR1 A;  3FM3 A;  2BWS A;  5E5B A;  1BN5 A;  2V6C A;  5CLS A;  1WN1 A;  2GTX A;  4RZY A;  2ADU A;  5FCF A;  1O0X A;  1XGN A;  1YW8 A;  1BOA A;  5JI6 A;  4IU6 A;  1R5G A;  4U75 A;  4U69 A;  5CE6 A;  3PKC A;  4ZNG A;  3S6B A;  1YJ3 A;  1KQ0 A;  4FUK A;  4S2T P;  1WL9 A;  1C24 A;  2BHB A;  4FO7 A;  2GZ5 A;  4IKR A;  4R60 A;  1YVM A;  2EA4 A;  3L24 A;  4IKS A;  4IKU A;  2P99 A;  1B59 A;  2BHC A;  5FCH A;  4PV4 A;  2V3Z A;  2MAT A;  1KQ9 A;  2EVM A;  1XGM A;  4IPA A;  4FLI A;  3BIT A;  4QR8 A;  4PNC A;  4FKC A;  5CDV A;  1C23 A;  5D6E A;  2Q95 A;  1W7V A;  1M35 A;  1XNZ A;  5D6F A;  4MAT A;  4U1B A;  1B6A A;  1WKM A;  2Q96 A;  3IL0 A;  3RVA A;  3TB5 A;  1A16 A;  3CB5 A;  3I7M A;  3IG4 A;  4ZWO A;  1CHM A;  3PEB A;  3PN9 A;  3IU7 A;  4FLK A;  4U71 A;  2Q93 A;  2OKN A;  2V3X A;  3FMR A;  2EVO A;  4U70 A;  2IW2 A;  1WY2 A;  2BWU A;  3Q6D A;  5CDE A;  2GGC A;  3ROR A;  4U6W A;  1C22 A;  5E2C A;  3CB6 A;  5CIK A; 
#chains in the Genus database with same CATH homology
 5CNX A;  2BH3 A;  2BN7 A;  4RZZ A;  4A6W A;  2B3H A;  2OAZ A;  2GG9 A;  2HOW A;  1QXW A;  3OOO A;  4A6V A;  1N51 A;  1WBQ A;  4U76 A;  3TAV A;  2BWW A;  2GU5 A;  1Y1N A;  5JHU A;  2GA2 A;  4ZWU A;  4ZWP A;  2Q94 A;  1YW9 A;  3O5V A;  2GG3 A;  1XGS A;  2GU6 A;  4RGZ 1;  2BB7 A;  2GU4 A;  1YW7 A;  3BIQ A;  4B28 A;  4U6E A;  4FO8 A;  4KM3 A;  1QXZ A;  4IKT A;  1WLR A;  2BWY A;  2BWT A;  4U6Z A;  2Q8K A;  2B3K A;  4Z7M A;  3MX6 A;  2GG7 A;  4IEC A;  4EGE A;  4IF7 A;  1C21 A;  5CDL A;  2V3Y A;  2EVC A;  3OVK A;  4S2R P;  2ZSG A;  2Q92 A;  3QOC A;  2GG2 A;  3D27 A;  4FLJ A;  3PKE A;  1W2M A;  2BHA A;  4S00 A;  2B3L A;  1XGO A;  4S01 A;  1R58 A;  2GG5 A;  1KP0 A;  2GG8 A;  2G6P A;  2GGB A;  4HXX A;  1R5H A;  3BIP A;  3IU9 A;  1QXY A;  2EA2 A;  2GU7 A;  2DFI A;  3PKD A;  4FLL A;  3IU8 A;  2GG0 A;  4JUQ A;  1C27 A;  4U6C A;  2BHD A;  2NQ6 A;  1PV9 A;  4IDY A;  1WL6 A;  4U73 A;  3PKB A;  5JFR A;  3CTZ A;  2BWX A;  2P98 A;  3MAT A;  4OOK A;  3PKA A;  1JAW A;  3L7G A;  2P9A A;  2BWV A;  1QZY A;  3FMQ A;  4U6J A;  2NQ7 A;  1MAT A;  3MR1 A;  3FM3 A;  2BWS A;  5E5B A;  1BN5 A;  2V6C A;  5CLS A;  1WN1 A;  2GTX A;  4RZY A;  2ADU A;  5FCF A;  1O0X A;  1XGN A;  1YW8 A;  1BOA A;  5JI6 A;  4IU6 A;  1R5G A;  4U75 A;  4U69 A;  5CE6 A;  3PKC A;  4ZNG A;  3S6B A;  1YJ3 A;  1KQ0 A;  4FUK A;  4S2T P;  1WL9 A;  1C24 A;  2BHB A;  4FO7 A;  2GZ5 A;  4IKR A;  4R60 A;  1YVM A;  2EA4 A;  3L24 A;  4IKS A;  4IKU A;  2P99 A;  1B59 A;  2BHC A;  5FCH A;  4PV4 A;  2V3Z A;  2MAT A;  1KQ9 A;  2EVM A;  1XGM A;  4IPA A;  4FLI A;  3BIT A;  4QR8 A;  4PNC A;  4FKC A;  5CDV A;  1C23 A;  5D6E A;  2Q95 A;  1W7V A;  1M35 A;  1XNZ A;  5D6F A;  4MAT A;  4U1B A;  1B6A A;  1WKM A;  2Q96 A;  3IL0 A;  3RVA A;  3TB5 A;  1A16 A;  3CB5 A;  3I7M A;  3IG4 A;  4ZWO A;  1CHM A;  3PEB A;  3PN9 A;  3IU7 A;  4FLK A;  4U71 A;  2Q93 A;  2OKN A;  2V3X A;  3FMR A;  2EVO A;  4U70 A;  2IW2 A;  1WY2 A;  2BWU A;  3Q6D A;  5CDE A;  2GGC A;  3ROR A;  4U6W A;  1C22 A;  5E2C A;  3CB6 A;  5CIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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