1CHMA

Enzymatic mechanism of creatine amidinohydrolase as deduced from crystal structures
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
401
structure length
401
Chain Sequence
QMPKTLRIRNGDKVRSTFSAQEYANRQARLRAHLAAENIDAAIFTSYHNINYYSDFLYCSFGRPYALVVTEDDVISISANIDGGQPWRRTVGTDNIVYTDWQRDNYFAAIQQALPKARRIGIEHDHLNLQNRDKLAARYPDAELVDVAAACMRMRMIKSAEEHVMIRHGARIADIGGAAVVEALGDQVPEYEVALHATQAMVRAIADTFEDVELMDTWTWFQSGINTDGAHNPVTTRKVNKGDILSLNCFPMIAGYYTALERTLFLDHCSDDHLRLWQVNVEVHEAGLKLIKPGARCSDIARELNEIFLKHDVLQYRTFGYGHSFGTLSHYYGREAGLELREDIDTVLEPGMVVSMEPMIMLPEGLPGAGGYREHDILIVNENGAENITKFPYGPEKNIIR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CREATINE AMIDINOHYDROLASE
publication title Enzymatic mechanism of creatine amidinohydrolase as deduced from crystal structures.
pubmed doi rcsb
source organism Pseudomonas putida
molecule tags Creatinase
total genus 143
structure length 401
sequence length 401
chains with identical sequence B
ec nomenclature ec 3.5.3.3: Creatinase.
pdb deposition date 1993-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1chmA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1chmA02
1BN5A 3BIPA 1YJ3A 1R5HA 2Q92A 3S6BA 4FLLA 3OOOA 2BB7A 2GG2A 2GU7A 1MATA 2HOWA 2V3YA 1WLRA 2Q94A 4KM3A 4QR8A 5D6FA 2BHDA 2GGCA 4IKUA 3MATA 4IPAA 3BIQA 2Q93A 4ZWOA 1XNZA 3PEBA 3MR1A 4RZZA 2OAZA 4RGZ1 5CIKA 3MX6A 2GU5A 2DFIA 4ZWPA 1PV9A 4IKTA 5FCFA 3RVAA 2B3HA 2BWSA 3Q6DA 1XGOA 2GG0A 4IKRA 3FMQA 4U6WA 3TB5A 2GA2A 1WBQA 1KP0A 2B3KA 5CNXA 1JAWA 1B6AA 2EVCA 3CB6A 4FO8A 1YW9A 2NQ6A 1C22A 2GZ5A 4IU6A 2BHAA 3I7MA 4U6EA 2BWVA 2GTXA 3CTZA 1W2MA 2V3ZA 2GG7A 2IW2A 3CB5A 3IU8A 5CDLA 4U75A 5CDVA 1C24A 3L7GA 1CHMA 4B28A 3O5VA 3BITA 1A16A 3IG4A 4U73A 4EGEA 1QXWA 1QXZA 3PKCA 4U70A 2BWXA 2Q8KA 4FLJA 2BWWA 1KQ0A 5D6EA 2BHCA 1YW8A 2G6PA 2GGBA 3PKEA 1C21A 3PKDA 1O0XA 4IDYA 4U6CA 5CLSA 4ZNGA 5E2CA 4S2TP 3QOCA 2GG8A 2EVOA 4FLIA 3PN9A 3PKAA 2MATA 2P99A 2BN7A 3PKBA 5FCHA 3FMRA 2V6CA 4S01A 2ZSGA 4FO7A 4Z7MA 5JI6A 3IL0A 1KQ9A 2Q95A 2BWTA 2BWUA 1XGNA 2NQ7A 3D27A 4U1BA 1W7VA 4A6VA 1YVMA 1R5GA 3RORA 1C27A 1QZYA 5JHUA 4IECA 2GU4A 4FUKA 1WKMA 3IU9A 4RZYA 2BWYA 2EA4A 5CDEA 3OVKA 1YW7A 4U71A 1WL6A 4ZWUA 4A6WA 4S2RP 2EA2A 1N51A 2V3XA 5E5BA 4S00A 2BHBA 1WN1A 1B59A 1QXYA 2Q96A 4R60A 4U6JA 1XGMA 5JFRA 5CE6A 4JUQA 2GG5A 2BH3A 2GU6A 3IU7A 2EVMA 1WY2A 2B3LA 4PNCA 1M35A 2P9AA 4PV4A 4FKCA 1BOAA 2OKNA 4IF7A 4U76A 4IKSA 2GG9A 4MATA 1WL9A 1R58A 4HXXA 1XGSA 2P98A 3FM3A 1C23A 2GG3A 4OOKA 3TAVA 2ADUA 4FLKA 3L24A 4U6ZA 4U69A 1Y1NA
chains in the Genus database with same CATH superfamily
1BN5A 3BIPA 1YJ3A 1R5HA 2Q92A 3S6BA 4FLLA 3OOOA 2BB7A 2GG2A 2GU7A 1MATA 2HOWA 2V3YA 1WLRA 2Q94A 4KM3A 4QR8A 5D6FA 2BHDA 2GGCA 4IKUA 3MATA 4IPAA 3BIQA 2Q93A 4ZWOA 1XNZA 3PEBA 3MR1A 4RZZA 2OAZA 4RGZ1 5CIKA 3MX6A 2GU5A 2DFIA 4ZWPA 1PV9A 4IKTA 5FCFA 3RVAA 2B3HA 2BWSA 3Q6DA 1XGOA 2GG0A 4IKRA 3FMQA 4U6WA 3TB5A 2GA2A 1WBQA 1KP0A 2B3KA 5CNXA 1JAWA 1B6AA 2EVCA 3CB6A 4FO8A 1YW9A 2NQ6A 1C22A 2GZ5A 4IU6A 2BHAA 3I7MA 4U6EA 2BWVA 2GTXA 3CTZA 1W2MA 2V3ZA 2GG7A 2IW2A 3CB5A 3IU8A 5CDLA 4U75A 5CDVA 1C24A 3L7GA 1CHMA 4B28A 3O5VA 3BITA 1A16A 3IG4A 4U73A 4EGEA 1QXWA 1QXZA 3PKCA 4U70A 2BWXA 2Q8KA 4FLJA 2BWWA 1KQ0A 5D6EA 2BHCA 1YW8A 2G6PA 2GGBA 3PKEA 1C21A 3PKDA 1O0XA 4IDYA 4U6CA 5CLSA 4ZNGA 5E2CA 4S2TP 3QOCA 2GG8A 2EVOA 4FLIA 3PN9A 3PKAA 2MATA 2P99A 2BN7A 3PKBA 5FCHA 3FMRA 2V6CA 4S01A 2ZSGA 4FO7A 4Z7MA 5JI6A 3IL0A 1KQ9A 2Q95A 2BWTA 2BWUA 1XGNA 2NQ7A 3D27A 4U1BA 1W7VA 4A6VA 1YVMA 1R5GA 3RORA 1C27A 1QZYA 5JHUA 4IECA 2GU4A 4FUKA 1WKMA 3IU9A 4RZYA 2BWYA 2EA4A 5CDEA 3OVKA 1YW7A 4U71A 1WL6A 4ZWUA 4A6WA 4S2RP 2EA2A 1N51A 2V3XA 5E5BA 4S00A 2BHBA 1WN1A 1B59A 1QXYA 2Q96A 4R60A 4U6JA 1XGMA 5JFRA 5CE6A 4JUQA 2GG5A 2BH3A 2GU6A 3IU7A 2EVMA 1WY2A 2B3LA 4PNCA 1M35A 2P9AA 4PV4A 4FKCA 1BOAA 2OKNA 4IF7A 4U76A 4IKSA 2GG9A 4MATA 1WL9A 1R58A 4HXXA 1XGSA 2P98A 3FM3A 1C23A 2GG3A 4OOKA 3TAVA 2ADUA 4FLKA 3L24A 4U6ZA 4U69A 1Y1NA
chains in the Genus database with same CATH topology
1BN5A 3BIPA 1YJ3A 1R5HA 2Q92A 3S6BA 4FLLA 3OOOA 2BB7A 2GG2A 2GU7A 1MATA 2HOWA 2V3YA 1WLRA 2Q94A 4KM3A 4QR8A 5D6FA 2BHDA 2GGCA 4IKUA 3MATA 4IPAA 3BIQA 2Q93A 4ZWOA 1XNZA 3PEBA 3MR1A 4RZZA 2OAZA 4RGZ1 5CIKA 3MX6A 2GU5A 2DFIA 4ZWPA 1PV9A 4IKTA 5FCFA 3RVAA 2B3HA 2BWSA 3Q6DA 1XGOA 2GG0A 4IKRA 3FMQA 4U6WA 3TB5A 2GA2A 1WBQA 1KP0A 2B3KA 5CNXA 1JAWA 1B6AA 2EVCA 3CB6A 4FO8A 1YW9A 2NQ6A 1C22A 2GZ5A 4IU6A 2BHAA 3I7MA 4U6EA 2BWVA 2GTXA 3CTZA 1W2MA 2V3ZA 2GG7A 2IW2A 3CB5A 3IU8A 5CDLA 4U75A 5CDVA 1C24A 3L7GA 1CHMA 4B28A 3O5VA 3BITA 1A16A 3IG4A 4U73A 4EGEA 1QXWA 1QXZA 3PKCA 4U70A 2BWXA 2Q8KA 4FLJA 2BWWA 1KQ0A 5D6EA 2BHCA 1YW8A 2G6PA 2GGBA 3PKEA 1C21A 3PKDA 1O0XA 4IDYA 4U6CA 5CLSA 4ZNGA 5E2CA 4S2TP 3QOCA 2GG8A 2EVOA 4FLIA 3PN9A 3PKAA 2MATA 2P99A 2BN7A 3PKBA 5FCHA 3FMRA 2V6CA 4S01A 2ZSGA 4FO7A 4Z7MA 5JI6A 3IL0A 1KQ9A 2Q95A 2BWTA 2BWUA 1XGNA 2NQ7A 3D27A 4U1BA 1W7VA 4A6VA 1YVMA 1R5GA 3RORA 1C27A 1QZYA 5JHUA 4IECA 2GU4A 4FUKA 1WKMA 3IU9A 4RZYA 2BWYA 2EA4A 5CDEA 3OVKA 1YW7A 4U71A 1WL6A 4ZWUA 4A6WA 4S2RP 2EA2A 1N51A 2V3XA 5E5BA 4S00A 2BHBA 1WN1A 1B59A 1QXYA 2Q96A 4R60A 4U6JA 1XGMA 5JFRA 5CE6A 4JUQA 2GG5A 2BH3A 2GU6A 3IU7A 2EVMA 1WY2A 2B3LA 4PNCA 1M35A 2P9AA 4PV4A 4FKCA 1BOAA 2OKNA 4IF7A 4U76A 4IKSA 2GG9A 4MATA 1WL9A 1R58A 4HXXA 1XGSA 2P98A 3FM3A 1C23A 2GG3A 4OOKA 3TAVA 2ADUA 4FLKA 3L24A 4U6ZA 4U69A 1Y1NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BN5 A;  3BIP A;  1YJ3 A;  1R5H A;  2Q92 A;  3S6B A;  4FLL A;  3OOO A;  2BB7 A;  2GG2 A;  2GU7 A;  1MAT A;  2HOW A;  2V3Y A;  1WLR A;  2Q94 A;  4KM3 A;  4QR8 A;  5D6F A;  2BHD A;  2GGC A;  4IKU A;  3MAT A;  4IPA A;  3BIQ A;  2Q93 A;  4ZWO A;  1XNZ A;  3PEB A;  3MR1 A;  4RZZ A;  2OAZ A;  4RGZ 1;  5CIK A;  3MX6 A;  2GU5 A;  2DFI A;  4ZWP A;  1PV9 A;  4IKT A;  5FCF A;  3RVA A;  2B3H A;  2BWS A;  3Q6D A;  1XGO A;  2GG0 A;  4IKR A;  3FMQ A;  4U6W A;  3TB5 A;  2GA2 A;  1WBQ A;  1KP0 A;  2B3K A;  5CNX A;  1JAW A;  1B6A A;  2EVC A;  3CB6 A;  4FO8 A;  1YW9 A;  2NQ6 A;  1C22 A;  2GZ5 A;  4IU6 A;  2BHA A;  3I7M A;  4U6E A;  2BWV A;  2GTX A;  3CTZ A;  1W2M A;  2V3Z A;  2GG7 A;  2IW2 A;  3CB5 A;  3IU8 A;  5CDL A;  4U75 A;  5CDV A;  1C24 A;  3L7G A;  1CHM A;  4B28 A;  3O5V A;  3BIT A;  1A16 A;  3IG4 A;  4U73 A;  4EGE A;  1QXW A;  1QXZ A;  3PKC A;  4U70 A;  2BWX A;  2Q8K A;  4FLJ A;  2BWW A;  1KQ0 A;  5D6E A;  2BHC A;  1YW8 A;  2G6P A;  2GGB A;  3PKE A;  1C21 A;  3PKD A;  1O0X A;  4IDY A;  4U6C A;  5CLS A;  4ZNG A;  5E2C A;  4S2T P;  3QOC A;  2GG8 A;  2EVO A;  4FLI A;  3PN9 A;  3PKA A;  2MAT A;  2P99 A;  2BN7 A;  3PKB A;  5FCH A;  3FMR A;  2V6C A;  4S01 A;  2ZSG A;  4FO7 A;  4Z7M A;  5JI6 A;  3IL0 A;  1KQ9 A;  2Q95 A;  2BWT A;  2BWU A;  1XGN A;  2NQ7 A;  3D27 A;  4U1B A;  1W7V A;  4A6V A;  1YVM A;  1R5G A;  3ROR A;  1C27 A;  1QZY A;  5JHU A;  4IEC A;  2GU4 A;  4FUK A;  1WKM A;  3IU9 A;  4RZY A;  2BWY A;  2EA4 A;  5CDE A;  3OVK A;  1YW7 A;  4U71 A;  1WL6 A;  4ZWU A;  4A6W A;  4S2R P;  2EA2 A;  1N51 A;  2V3X A;  5E5B A;  4S00 A;  2BHB A;  1WN1 A;  1B59 A;  1QXY A;  2Q96 A;  4R60 A;  4U6J A;  1XGM A;  5JFR A;  5CE6 A;  4JUQ A;  2GG5 A;  2BH3 A;  2GU6 A;  3IU7 A;  2EVM A;  1WY2 A;  2B3L A;  4PNC A;  1M35 A;  2P9A A;  4PV4 A;  4FKC A;  1BOA A;  2OKN A;  4IF7 A;  4U76 A;  4IKS A;  2GG9 A;  4MAT A;  1WL9 A;  1R58 A;  4HXX A;  1XGS A;  2P98 A;  3FM3 A;  1C23 A;  2GG3 A;  4OOK A;  3TAV A;  2ADU A;  4FLK A;  3L24 A;  4U6Z A;  4U69 A;  1Y1N A; 
#chains in the Genus database with same CATH topology
 1BN5 A;  3BIP A;  1YJ3 A;  1R5H A;  2Q92 A;  3S6B A;  4FLL A;  3OOO A;  2BB7 A;  2GG2 A;  2GU7 A;  1MAT A;  2HOW A;  2V3Y A;  1WLR A;  2Q94 A;  4KM3 A;  4QR8 A;  5D6F A;  2BHD A;  2GGC A;  4IKU A;  3MAT A;  4IPA A;  3BIQ A;  2Q93 A;  4ZWO A;  1XNZ A;  3PEB A;  3MR1 A;  4RZZ A;  2OAZ A;  4RGZ 1;  5CIK A;  3MX6 A;  2GU5 A;  2DFI A;  4ZWP A;  1PV9 A;  4IKT A;  5FCF A;  3RVA A;  2B3H A;  2BWS A;  3Q6D A;  1XGO A;  2GG0 A;  4IKR A;  3FMQ A;  4U6W A;  3TB5 A;  2GA2 A;  1WBQ A;  1KP0 A;  2B3K A;  5CNX A;  1JAW A;  1B6A A;  2EVC A;  3CB6 A;  4FO8 A;  1YW9 A;  2NQ6 A;  1C22 A;  2GZ5 A;  4IU6 A;  2BHA A;  3I7M A;  4U6E A;  2BWV A;  2GTX A;  3CTZ A;  1W2M A;  2V3Z A;  2GG7 A;  2IW2 A;  3CB5 A;  3IU8 A;  5CDL A;  4U75 A;  5CDV A;  1C24 A;  3L7G A;  1CHM A;  4B28 A;  3O5V A;  3BIT A;  1A16 A;  3IG4 A;  4U73 A;  4EGE A;  1QXW A;  1QXZ A;  3PKC A;  4U70 A;  2BWX A;  2Q8K A;  4FLJ A;  2BWW A;  1KQ0 A;  5D6E A;  2BHC A;  1YW8 A;  2G6P A;  2GGB A;  3PKE A;  1C21 A;  3PKD A;  1O0X A;  4IDY A;  4U6C A;  5CLS A;  4ZNG A;  5E2C A;  4S2T P;  3QOC A;  2GG8 A;  2EVO A;  4FLI A;  3PN9 A;  3PKA A;  2MAT A;  2P99 A;  2BN7 A;  3PKB A;  5FCH A;  3FMR A;  2V6C A;  4S01 A;  2ZSG A;  4FO7 A;  4Z7M A;  5JI6 A;  3IL0 A;  1KQ9 A;  2Q95 A;  2BWT A;  2BWU A;  1XGN A;  2NQ7 A;  3D27 A;  4U1B A;  1W7V A;  4A6V A;  1YVM A;  1R5G A;  3ROR A;  1C27 A;  1QZY A;  5JHU A;  4IEC A;  2GU4 A;  4FUK A;  1WKM A;  3IU9 A;  4RZY A;  2BWY A;  2EA4 A;  5CDE A;  3OVK A;  1YW7 A;  4U71 A;  1WL6 A;  4ZWU A;  4A6W A;  4S2R P;  2EA2 A;  1N51 A;  2V3X A;  5E5B A;  4S00 A;  2BHB A;  1WN1 A;  1B59 A;  1QXY A;  2Q96 A;  4R60 A;  4U6J A;  1XGM A;  5JFR A;  5CE6 A;  4JUQ A;  2GG5 A;  2BH3 A;  2GU6 A;  3IU7 A;  2EVM A;  1WY2 A;  2B3L A;  4PNC A;  1M35 A;  2P9A A;  4PV4 A;  4FKC A;  1BOA A;  2OKN A;  4IF7 A;  4U76 A;  4IKS A;  2GG9 A;  4MAT A;  1WL9 A;  1R58 A;  4HXX A;  1XGS A;  2P98 A;  3FM3 A;  1C23 A;  2GG3 A;  4OOK A;  3TAV A;  2ADU A;  4FLK A;  3L24 A;  4U6Z A;  4U69 A;  1Y1N A; 
#chains in the Genus database with same CATH homology
 1BN5 A;  3BIP A;  1YJ3 A;  1R5H A;  2Q92 A;  3S6B A;  4FLL A;  3OOO A;  2BB7 A;  2GG2 A;  2GU7 A;  1MAT A;  2HOW A;  2V3Y A;  1WLR A;  2Q94 A;  4KM3 A;  4QR8 A;  5D6F A;  2BHD A;  2GGC A;  4IKU A;  3MAT A;  4IPA A;  3BIQ A;  2Q93 A;  4ZWO A;  1XNZ A;  3PEB A;  3MR1 A;  4RZZ A;  2OAZ A;  4RGZ 1;  5CIK A;  3MX6 A;  2GU5 A;  2DFI A;  4ZWP A;  1PV9 A;  4IKT A;  5FCF A;  3RVA A;  2B3H A;  2BWS A;  3Q6D A;  1XGO A;  2GG0 A;  4IKR A;  3FMQ A;  4U6W A;  3TB5 A;  2GA2 A;  1WBQ A;  1KP0 A;  2B3K A;  5CNX A;  1JAW A;  1B6A A;  2EVC A;  3CB6 A;  4FO8 A;  1YW9 A;  2NQ6 A;  1C22 A;  2GZ5 A;  4IU6 A;  2BHA A;  3I7M A;  4U6E A;  2BWV A;  2GTX A;  3CTZ A;  1W2M A;  2V3Z A;  2GG7 A;  2IW2 A;  3CB5 A;  3IU8 A;  5CDL A;  4U75 A;  5CDV A;  1C24 A;  3L7G A;  1CHM A;  4B28 A;  3O5V A;  3BIT A;  1A16 A;  3IG4 A;  4U73 A;  4EGE A;  1QXW A;  1QXZ A;  3PKC A;  4U70 A;  2BWX A;  2Q8K A;  4FLJ A;  2BWW A;  1KQ0 A;  5D6E A;  2BHC A;  1YW8 A;  2G6P A;  2GGB A;  3PKE A;  1C21 A;  3PKD A;  1O0X A;  4IDY A;  4U6C A;  5CLS A;  4ZNG A;  5E2C A;  4S2T P;  3QOC A;  2GG8 A;  2EVO A;  4FLI A;  3PN9 A;  3PKA A;  2MAT A;  2P99 A;  2BN7 A;  3PKB A;  5FCH A;  3FMR A;  2V6C A;  4S01 A;  2ZSG A;  4FO7 A;  4Z7M A;  5JI6 A;  3IL0 A;  1KQ9 A;  2Q95 A;  2BWT A;  2BWU A;  1XGN A;  2NQ7 A;  3D27 A;  4U1B A;  1W7V A;  4A6V A;  1YVM A;  1R5G A;  3ROR A;  1C27 A;  1QZY A;  5JHU A;  4IEC A;  2GU4 A;  4FUK A;  1WKM A;  3IU9 A;  4RZY A;  2BWY A;  2EA4 A;  5CDE A;  3OVK A;  1YW7 A;  4U71 A;  1WL6 A;  4ZWU A;  4A6W A;  4S2R P;  2EA2 A;  1N51 A;  2V3X A;  5E5B A;  4S00 A;  2BHB A;  1WN1 A;  1B59 A;  1QXY A;  2Q96 A;  4R60 A;  4U6J A;  1XGM A;  5JFR A;  5CE6 A;  4JUQ A;  2GG5 A;  2BH3 A;  2GU6 A;  3IU7 A;  2EVM A;  1WY2 A;  2B3L A;  4PNC A;  1M35 A;  2P9A A;  4PV4 A;  4FKC A;  1BOA A;  2OKN A;  4IF7 A;  4U76 A;  4IKS A;  2GG9 A;  4MAT A;  1WL9 A;  1R58 A;  4HXX A;  1XGS A;  2P98 A;  3FM3 A;  1C23 A;  2GG3 A;  4OOK A;  3TAV A;  2ADU A;  4FLK A;  3L24 A;  4U6Z A;  4U69 A;  1Y1N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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