1CHMA

Enzymatic mechanism of creatine amidinohydrolase as deduced from crystal structures
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
401
structure length
401
Chain Sequence
b'QMPKTLRIRNGDKVRSTFSAQEYANRQARLRAHLAAENIDAAIFTSYHNINYYSDFLYCSFGRPYALVVTEDDVISISANIDGGQPWRRTVGTDNIVYTDWQRDNYFAAIQQALPKARRIGIEHDHLNLQNRDKLAARYPDAELVDVAAACMRMRMIKSAEEHVMIRHGARIADIGGAAVVEALGDQVPEYEVALHATQAMVRAIADTFEDVELMDTWTWFQSGINTDGAHNPVTTRKVNKGDILSLNCFPMIAGYYTALERTLFLDHCSDDHLRLWQVNVEVHEAGLKLIKPGARCSDIARELNEIFLKHDVLQYRTFGYGHSFGTLSHYYGREAGLELREDIDTVLEPGMVVSMEPMIMLPEGLPGAGGYREHDILIVNENGAENITKFPYGPEKNIIR'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CREATINE AMIDINOHYDROLASE
publication title Enzymatic mechanism of creatine amidinohydrolase as deduced from crystal structures.
pubmed doi rcsb
source organism Pseudomonas putida
molecule tags Creatinase
total genus 143
structure length 401
sequence length 401
chains with identical sequence B
ec nomenclature ec 3.5.3.3: Creatinase.
pdb deposition date 1993-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1chmA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1chmA02
4RZZA 1O0XA 3FMQA 1QXWA 1C23A 4EGEA 5JHUA 5FCFA 5E2CA 4U73A 1WY2A 2EVCA 4IF7A 2B3LA 3RORA 5FCHA 1W2MA 4ZWUA 3BIQA 1KQ0A 1KP0A 3PEBA 2P98A 4KM3A 4PNCA 1WLRA 5CDEA 4Z7MA 1WN1A 2IW2A 1XGNA 1YW8A 1N51A 2Q93A 4FLKA 4U75A 4U6ZA 1C21A 2B3KA 4B28A 1QZYA 2GGCA 2GU4A 2OAZA 2BHDA 4U70A 4U1BA 2BWUA 1C22A 2BWTA 2Q95A 2Q8KA 2GG7A 2BH3A 4R60A 5E5BA 2BWXA 3I7MA 3OVKA 2V6CA 3BITA 4S01A 2P9AA 2GU7A 4U71A 3Q6DA 2BWSA 4ZNGA 2GG8A 2ZSGA 2GG5A 2NQ6A 4U6JA 3PN9A 4U6CA 3IU9A 5CE6A 4IKUA 3QOCA 3BIPA 4FO7A 1QXZA 3OOOA 1C27A 1PV9A 2V3YA 2GA2A 4IPAA 4FLJA 1YVMA 1R58A 1R5GA 2NQ7A 4HXXA 1WKMA 2V3XA 3PKCA 2BB7A 4IKRA 5CDVA 4IKTA 1XGMA 2EA4A 2GGBA 3PKBA 3TAVA 4IKSA 1JAWA 3IU7A 3FMRA 2EA2A 3TB5A 3FM3A 4FLLA 2EVMA 2DFIA 4OOKA 4IECA 2BWWA 4IDYA 2BHCA 1XGSA 2HOWA 3MX6A 4FKCA 5D6FA 4ZWOA 3RVAA 4FO8A 4U76A 4ZWPA 1KQ9A 4JUQA 4A6WA 2GG0A 4MATA 3MATA 2B3HA 1B59A 1WBQA 1WL9A 5CIKA 2ADUA 1YW9A 3IL0A 1Y1NA 4S00A 4RGZ1 4IU6A 5CNXA 2BN7A 5CDLA 5CLSA 4S2TP 3CTZA 3CB5A 2Q94A 1BN5A 5JI6A 4U6EA 4U6WA 3O5VA 3L7GA 1A16A 2BHAA 4QR8A 1WL6A 2OKNA 2GU5A 2GZ5A 3D27A 3MR1A 2G6PA 1BOAA 2Q96A 4PV4A 1YW7A 2Q92A 4A6VA 2BWYA 1R5HA 1MATA 1XGOA 5D6EA 2V3ZA 3IG4A 2MATA 3S6BA 2GU6A 3PKEA 1M35A 2GG2A 4FUKA 4FLIA 1B6AA 3L24A 1XNZA 4U69A 1CHMA 1QXYA 3IU8A 4RZYA 1W7VA 4S2RP 2P99A 2GG9A 3PKAA 3PKDA 2BHBA 1YJ3A 2BWVA 2GG3A 3CB6A 2GTXA 2EVOA 1C24A 5JFRA
chains in the Genus database with same CATH superfamily
4RZZA 1O0XA 3FMQA 1QXWA 1C23A 4EGEA 5JHUA 5FCFA 5E2CA 4U73A 1WY2A 2EVCA 4IF7A 2B3LA 3RORA 5FCHA 1W2MA 4ZWUA 3BIQA 1KQ0A 1KP0A 3PEBA 2P98A 4KM3A 4PNCA 1WLRA 5CDEA 4Z7MA 1WN1A 2IW2A 1XGNA 1YW8A 1N51A 2Q93A 4FLKA 4U75A 4U6ZA 1C21A 2B3KA 4B28A 1QZYA 2GGCA 2GU4A 2OAZA 2BHDA 4U70A 4U1BA 2BWUA 1C22A 2BWTA 2Q95A 2Q8KA 2GG7A 2BH3A 4R60A 5E5BA 2BWXA 3I7MA 3OVKA 2V6CA 3BITA 4S01A 2P9AA 2GU7A 4U71A 3Q6DA 2BWSA 4ZNGA 2GG8A 2ZSGA 2GG5A 2NQ6A 4U6JA 3PN9A 4U6CA 3IU9A 5CE6A 4IKUA 3QOCA 3BIPA 4FO7A 1QXZA 3OOOA 1C27A 1PV9A 2V3YA 2GA2A 4IPAA 4FLJA 1YVMA 1R58A 1R5GA 2NQ7A 4HXXA 1WKMA 2V3XA 3PKCA 2BB7A 4IKRA 5CDVA 4IKTA 1XGMA 2EA4A 2GGBA 3PKBA 3TAVA 4IKSA 1JAWA 3IU7A 3FMRA 2EA2A 3TB5A 3FM3A 4FLLA 2EVMA 2DFIA 4OOKA 4IECA 2BWWA 4IDYA 2BHCA 1XGSA 2HOWA 3MX6A 4FKCA 5D6FA 4ZWOA 3RVAA 4FO8A 4U76A 4ZWPA 1KQ9A 4JUQA 4A6WA 2GG0A 4MATA 3MATA 2B3HA 1B59A 1WBQA 1WL9A 5CIKA 2ADUA 1YW9A 3IL0A 1Y1NA 4S00A 4RGZ1 4IU6A 5CNXA 2BN7A 5CDLA 5CLSA 4S2TP 3CTZA 3CB5A 2Q94A 1BN5A 5JI6A 4U6EA 4U6WA 3O5VA 3L7GA 1A16A 2BHAA 4QR8A 1WL6A 2OKNA 2GU5A 2GZ5A 3D27A 3MR1A 2G6PA 1BOAA 2Q96A 4PV4A 1YW7A 2Q92A 4A6VA 2BWYA 1R5HA 1MATA 1XGOA 5D6EA 2V3ZA 3IG4A 2MATA 3S6BA 2GU6A 3PKEA 1M35A 2GG2A 4FUKA 4FLIA 1B6AA 3L24A 1XNZA 4U69A 1CHMA 1QXYA 3IU8A 4RZYA 1W7VA 4S2RP 2P99A 2GG9A 3PKAA 3PKDA 2BHBA 1YJ3A 2BWVA 2GG3A 3CB6A 2GTXA 2EVOA 1C24A 5JFRA
chains in the Genus database with same CATH topology
4RZZA 1O0XA 3FMQA 1QXWA 1C23A 4EGEA 5JHUA 5FCFA 5E2CA 4U73A 1WY2A 2EVCA 4IF7A 2B3LA 3RORA 5FCHA 1W2MA 4ZWUA 3BIQA 1KQ0A 1KP0A 3PEBA 2P98A 4KM3A 4PNCA 1WLRA 5CDEA 4Z7MA 1WN1A 2IW2A 1XGNA 1YW8A 1N51A 2Q93A 4FLKA 4U75A 4U6ZA 1C21A 2B3KA 4B28A 1QZYA 2GGCA 2GU4A 2OAZA 2BHDA 4U70A 4U1BA 2BWUA 1C22A 2BWTA 2Q95A 2Q8KA 2GG7A 2BH3A 4R60A 5E5BA 2BWXA 3I7MA 3OVKA 2V6CA 3BITA 4S01A 2P9AA 2GU7A 4U71A 3Q6DA 2BWSA 4ZNGA 2GG8A 2ZSGA 2GG5A 2NQ6A 4U6JA 3PN9A 4U6CA 3IU9A 5CE6A 4IKUA 3QOCA 3BIPA 4FO7A 1QXZA 3OOOA 1C27A 1PV9A 2V3YA 2GA2A 4IPAA 4FLJA 1YVMA 1R58A 1R5GA 2NQ7A 4HXXA 1WKMA 2V3XA 3PKCA 2BB7A 4IKRA 5CDVA 4IKTA 1XGMA 2EA4A 2GGBA 3PKBA 3TAVA 4IKSA 1JAWA 3IU7A 3FMRA 2EA2A 3TB5A 3FM3A 4FLLA 2EVMA 2DFIA 4OOKA 4IECA 2BWWA 4IDYA 2BHCA 1XGSA 2HOWA 3MX6A 4FKCA 5D6FA 4ZWOA 3RVAA 4FO8A 4U76A 4ZWPA 1KQ9A 4JUQA 4A6WA 2GG0A 4MATA 3MATA 2B3HA 1B59A 1WBQA 1WL9A 5CIKA 2ADUA 1YW9A 3IL0A 1Y1NA 4S00A 4RGZ1 4IU6A 5CNXA 2BN7A 5CDLA 5CLSA 4S2TP 3CTZA 3CB5A 2Q94A 1BN5A 5JI6A 4U6EA 4U6WA 3O5VA 3L7GA 1A16A 2BHAA 4QR8A 1WL6A 2OKNA 2GU5A 2GZ5A 3D27A 3MR1A 2G6PA 1BOAA 2Q96A 4PV4A 1YW7A 2Q92A 4A6VA 2BWYA 1R5HA 1MATA 1XGOA 5D6EA 2V3ZA 3IG4A 2MATA 3S6BA 2GU6A 3PKEA 1M35A 2GG2A 4FUKA 4FLIA 1B6AA 3L24A 1XNZA 4U69A 1CHMA 1QXYA 3IU8A 4RZYA 1W7VA 4S2RP 2P99A 2GG9A 3PKAA 3PKDA 2BHBA 1YJ3A 2BWVA 2GG3A 3CB6A 2GTXA 2EVOA 1C24A 5JFRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RZZ A;  1O0X A;  3FMQ A;  1QXW A;  1C23 A;  4EGE A;  5JHU A;  5FCF A;  5E2C A;  4U73 A;  1WY2 A;  2EVC A;  4IF7 A;  2B3L A;  3ROR A;  5FCH A;  1W2M A;  4ZWU A;  3BIQ A;  1KQ0 A;  1KP0 A;  3PEB A;  2P98 A;  4KM3 A;  4PNC A;  1WLR A;  5CDE A;  4Z7M A;  1WN1 A;  2IW2 A;  1XGN A;  1YW8 A;  1N51 A;  2Q93 A;  4FLK A;  4U75 A;  4U6Z A;  1C21 A;  2B3K A;  4B28 A;  1QZY A;  2GGC A;  2GU4 A;  2OAZ A;  2BHD A;  4U70 A;  4U1B A;  2BWU A;  1C22 A;  2BWT A;  2Q95 A;  2Q8K A;  2GG7 A;  2BH3 A;  4R60 A;  5E5B A;  2BWX A;  3I7M A;  3OVK A;  2V6C A;  3BIT A;  4S01 A;  2P9A A;  2GU7 A;  4U71 A;  3Q6D A;  2BWS A;  4ZNG A;  2GG8 A;  2ZSG A;  2GG5 A;  2NQ6 A;  4U6J A;  3PN9 A;  4U6C A;  3IU9 A;  5CE6 A;  4IKU A;  3QOC A;  3BIP A;  4FO7 A;  1QXZ A;  3OOO A;  1C27 A;  1PV9 A;  2V3Y A;  2GA2 A;  4IPA A;  4FLJ A;  1YVM A;  1R58 A;  1R5G A;  2NQ7 A;  4HXX A;  1WKM A;  2V3X A;  3PKC A;  2BB7 A;  4IKR A;  5CDV A;  4IKT A;  1XGM A;  2EA4 A;  2GGB A;  3PKB A;  3TAV A;  4IKS A;  1JAW A;  3IU7 A;  3FMR A;  2EA2 A;  3TB5 A;  3FM3 A;  4FLL A;  2EVM A;  2DFI A;  4OOK A;  4IEC A;  2BWW A;  4IDY A;  2BHC A;  1XGS A;  2HOW A;  3MX6 A;  4FKC A;  5D6F A;  4ZWO A;  3RVA A;  4FO8 A;  4U76 A;  4ZWP A;  1KQ9 A;  4JUQ A;  4A6W A;  2GG0 A;  4MAT A;  3MAT A;  2B3H A;  1B59 A;  1WBQ A;  1WL9 A;  5CIK A;  2ADU A;  1YW9 A;  3IL0 A;  1Y1N A;  4S00 A;  4RGZ 1;  4IU6 A;  5CNX A;  2BN7 A;  5CDL A;  5CLS A;  4S2T P;  3CTZ A;  3CB5 A;  2Q94 A;  1BN5 A;  5JI6 A;  4U6E A;  4U6W A;  3O5V A;  3L7G A;  1A16 A;  2BHA A;  4QR8 A;  1WL6 A;  2OKN A;  2GU5 A;  2GZ5 A;  3D27 A;  3MR1 A;  2G6P A;  1BOA A;  2Q96 A;  4PV4 A;  1YW7 A;  2Q92 A;  4A6V A;  2BWY A;  1R5H A;  1MAT A;  1XGO A;  5D6E A;  2V3Z A;  3IG4 A;  2MAT A;  3S6B A;  2GU6 A;  3PKE A;  1M35 A;  2GG2 A;  4FUK A;  4FLI A;  1B6A A;  3L24 A;  1XNZ A;  4U69 A;  1CHM A;  1QXY A;  3IU8 A;  4RZY A;  1W7V A;  4S2R P;  2P99 A;  2GG9 A;  3PKA A;  3PKD A;  2BHB A;  1YJ3 A;  2BWV A;  2GG3 A;  3CB6 A;  2GTX A;  2EVO A;  1C24 A;  5JFR A; 
#chains in the Genus database with same CATH topology
 4RZZ A;  1O0X A;  3FMQ A;  1QXW A;  1C23 A;  4EGE A;  5JHU A;  5FCF A;  5E2C A;  4U73 A;  1WY2 A;  2EVC A;  4IF7 A;  2B3L A;  3ROR A;  5FCH A;  1W2M A;  4ZWU A;  3BIQ A;  1KQ0 A;  1KP0 A;  3PEB A;  2P98 A;  4KM3 A;  4PNC A;  1WLR A;  5CDE A;  4Z7M A;  1WN1 A;  2IW2 A;  1XGN A;  1YW8 A;  1N51 A;  2Q93 A;  4FLK A;  4U75 A;  4U6Z A;  1C21 A;  2B3K A;  4B28 A;  1QZY A;  2GGC A;  2GU4 A;  2OAZ A;  2BHD A;  4U70 A;  4U1B A;  2BWU A;  1C22 A;  2BWT A;  2Q95 A;  2Q8K A;  2GG7 A;  2BH3 A;  4R60 A;  5E5B A;  2BWX A;  3I7M A;  3OVK A;  2V6C A;  3BIT A;  4S01 A;  2P9A A;  2GU7 A;  4U71 A;  3Q6D A;  2BWS A;  4ZNG A;  2GG8 A;  2ZSG A;  2GG5 A;  2NQ6 A;  4U6J A;  3PN9 A;  4U6C A;  3IU9 A;  5CE6 A;  4IKU A;  3QOC A;  3BIP A;  4FO7 A;  1QXZ A;  3OOO A;  1C27 A;  1PV9 A;  2V3Y A;  2GA2 A;  4IPA A;  4FLJ A;  1YVM A;  1R58 A;  1R5G A;  2NQ7 A;  4HXX A;  1WKM A;  2V3X A;  3PKC A;  2BB7 A;  4IKR A;  5CDV A;  4IKT A;  1XGM A;  2EA4 A;  2GGB A;  3PKB A;  3TAV A;  4IKS A;  1JAW A;  3IU7 A;  3FMR A;  2EA2 A;  3TB5 A;  3FM3 A;  4FLL A;  2EVM A;  2DFI A;  4OOK A;  4IEC A;  2BWW A;  4IDY A;  2BHC A;  1XGS A;  2HOW A;  3MX6 A;  4FKC A;  5D6F A;  4ZWO A;  3RVA A;  4FO8 A;  4U76 A;  4ZWP A;  1KQ9 A;  4JUQ A;  4A6W A;  2GG0 A;  4MAT A;  3MAT A;  2B3H A;  1B59 A;  1WBQ A;  1WL9 A;  5CIK A;  2ADU A;  1YW9 A;  3IL0 A;  1Y1N A;  4S00 A;  4RGZ 1;  4IU6 A;  5CNX A;  2BN7 A;  5CDL A;  5CLS A;  4S2T P;  3CTZ A;  3CB5 A;  2Q94 A;  1BN5 A;  5JI6 A;  4U6E A;  4U6W A;  3O5V A;  3L7G A;  1A16 A;  2BHA A;  4QR8 A;  1WL6 A;  2OKN A;  2GU5 A;  2GZ5 A;  3D27 A;  3MR1 A;  2G6P A;  1BOA A;  2Q96 A;  4PV4 A;  1YW7 A;  2Q92 A;  4A6V A;  2BWY A;  1R5H A;  1MAT A;  1XGO A;  5D6E A;  2V3Z A;  3IG4 A;  2MAT A;  3S6B A;  2GU6 A;  3PKE A;  1M35 A;  2GG2 A;  4FUK A;  4FLI A;  1B6A A;  3L24 A;  1XNZ A;  4U69 A;  1CHM A;  1QXY A;  3IU8 A;  4RZY A;  1W7V A;  4S2R P;  2P99 A;  2GG9 A;  3PKA A;  3PKD A;  2BHB A;  1YJ3 A;  2BWV A;  2GG3 A;  3CB6 A;  2GTX A;  2EVO A;  1C24 A;  5JFR A; 
#chains in the Genus database with same CATH homology
 4RZZ A;  1O0X A;  3FMQ A;  1QXW A;  1C23 A;  4EGE A;  5JHU A;  5FCF A;  5E2C A;  4U73 A;  1WY2 A;  2EVC A;  4IF7 A;  2B3L A;  3ROR A;  5FCH A;  1W2M A;  4ZWU A;  3BIQ A;  1KQ0 A;  1KP0 A;  3PEB A;  2P98 A;  4KM3 A;  4PNC A;  1WLR A;  5CDE A;  4Z7M A;  1WN1 A;  2IW2 A;  1XGN A;  1YW8 A;  1N51 A;  2Q93 A;  4FLK A;  4U75 A;  4U6Z A;  1C21 A;  2B3K A;  4B28 A;  1QZY A;  2GGC A;  2GU4 A;  2OAZ A;  2BHD A;  4U70 A;  4U1B A;  2BWU A;  1C22 A;  2BWT A;  2Q95 A;  2Q8K A;  2GG7 A;  2BH3 A;  4R60 A;  5E5B A;  2BWX A;  3I7M A;  3OVK A;  2V6C A;  3BIT A;  4S01 A;  2P9A A;  2GU7 A;  4U71 A;  3Q6D A;  2BWS A;  4ZNG A;  2GG8 A;  2ZSG A;  2GG5 A;  2NQ6 A;  4U6J A;  3PN9 A;  4U6C A;  3IU9 A;  5CE6 A;  4IKU A;  3QOC A;  3BIP A;  4FO7 A;  1QXZ A;  3OOO A;  1C27 A;  1PV9 A;  2V3Y A;  2GA2 A;  4IPA A;  4FLJ A;  1YVM A;  1R58 A;  1R5G A;  2NQ7 A;  4HXX A;  1WKM A;  2V3X A;  3PKC A;  2BB7 A;  4IKR A;  5CDV A;  4IKT A;  1XGM A;  2EA4 A;  2GGB A;  3PKB A;  3TAV A;  4IKS A;  1JAW A;  3IU7 A;  3FMR A;  2EA2 A;  3TB5 A;  3FM3 A;  4FLL A;  2EVM A;  2DFI A;  4OOK A;  4IEC A;  2BWW A;  4IDY A;  2BHC A;  1XGS A;  2HOW A;  3MX6 A;  4FKC A;  5D6F A;  4ZWO A;  3RVA A;  4FO8 A;  4U76 A;  4ZWP A;  1KQ9 A;  4JUQ A;  4A6W A;  2GG0 A;  4MAT A;  3MAT A;  2B3H A;  1B59 A;  1WBQ A;  1WL9 A;  5CIK A;  2ADU A;  1YW9 A;  3IL0 A;  1Y1N A;  4S00 A;  4RGZ 1;  4IU6 A;  5CNX A;  2BN7 A;  5CDL A;  5CLS A;  4S2T P;  3CTZ A;  3CB5 A;  2Q94 A;  1BN5 A;  5JI6 A;  4U6E A;  4U6W A;  3O5V A;  3L7G A;  1A16 A;  2BHA A;  4QR8 A;  1WL6 A;  2OKN A;  2GU5 A;  2GZ5 A;  3D27 A;  3MR1 A;  2G6P A;  1BOA A;  2Q96 A;  4PV4 A;  1YW7 A;  2Q92 A;  4A6V A;  2BWY A;  1R5H A;  1MAT A;  1XGO A;  5D6E A;  2V3Z A;  3IG4 A;  2MAT A;  3S6B A;  2GU6 A;  3PKE A;  1M35 A;  2GG2 A;  4FUK A;  4FLI A;  1B6A A;  3L24 A;  1XNZ A;  4U69 A;  1CHM A;  1QXY A;  3IU8 A;  4RZY A;  1W7V A;  4S2R P;  2P99 A;  2GG9 A;  3PKA A;  3PKD A;  2BHB A;  1YJ3 A;  2BWV A;  2GG3 A;  3CB6 A;  2GTX A;  2EVO A;  1C24 A;  5JFR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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