1CKLA

N-terminal two domains of human cd46 (membrane cofactor protein, mcp)
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
126
structure length
126
Chain Sequence
CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of two CD46 domains reveals an extended measles virus-binding surface.
pubmed doi rcsb
molecule keywords PROTEIN (CD46)
molecule tags Glycoprotein
source organism Homo sapiens
total genus 17
structure length 126
sequence length 126
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 1999-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1cklA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1cklA01
1MD7A 2EC3A 1OK1A 2RKYA 4AYEA 4B2RA 3GOVA 1UOTP 4KKDA 3IU3I 4DJZA 3CALA 3KZJA 2CG7A 1OK3A 1VVDA 5HZPB 5I0QB 2JGWA 4F4OC 1OJWA 3ZRZA 2KRIA 2W81A 1H2QP 4YNXA 5HYUB 2JRAA 4ONTD 2O39C 2EHFA 1C1ZA 3EJHA 2MCZA 3L89M 4FXGG 1OK9A 1HCCA 3OEDC 5FO8C 4K12A 2XRBA 1LY2A 4AYMA 2YBYA 3O8EB 1Z92B 1HFIA 2BZMA 5HYTB 1ELVA 2IZ4A 3OXUD 2G7IA 2RLPA 2RLQA 1VVCA 2ERJA 1OJVA 2B5ID 2KMSA 4WJG2 1OK2A 1NWVA 2A55A 3M7PA 3GXEA 3ERBA 3NFPI 1FBRA 3ZD2A 1HFHA 3OP8A 3ZD1A 4CSYA 2IZ3A 2QY0A 2RKZA 1H2PP 2CG6A 1TPNA 2W80A 4IGDA 1GPZA 1O9AA 1OJYA 2XRDA 4B2SA 1Q3XA 4LOSA 1H04P 2LOJA 1GKGA 3IX0A 1PPQA 1SS2A 2XWJI 3T5OA 1H03P 4J38B 1TPMA 1SRZA 2MCYA 4AYIA 1U5MA 4C16A 5HYPA 4A5WB 1QUBA 2XQWC 1G4GA 1E8BA 1QGBA 2WIIC 2YRAA 5JPMG 1CKLA 1ZJKA 2RL0A 1MD8A 4PZ5A 3MQLA 4LOTA 4AYDA 2UWNA 1G4FA 3KXVA 1E5GA 2XWBF 4JHSA 1TPGA 3RJ3D 4MUCA 1E88A 1GKNA 3INBC 2V8EA 1QO6A 2CKUA 3R62A 4ZH1D 1GHQB 3TVJA 3SW0X 2JGXA
chains in the Genus database with same CATH superfamily
1MD7A 2EC3A 1OK1A 2X2ZA 2RKYA 4AYEA 4B2RA 3GOVA 3K3TA 1UOTP 3F6KA 4PO7A 2Y8SA 4KKDA 3IU3I 4DJZA 3CALA 5DN4A 3ZLEA 3KZJA 2CG7A 4YIZA 1OK3A 1VVDA 5HZPB 5I0QB 2JGWA 4F4OC 1OJWA 3ZRZA 2KRIA 2W81A 1H2QP 4YNXA 5HYUB 2JRAA 4ONTD 2O39C 3VWOA 2EHFA 1C1ZA 3EJHA 2MCZA 3L89M 4FXGG 1OK9A 1HCCA 3OEDC 5FO8C 4K12A 2XRBA 1LY2A 4MSLA 4AYMA 5DN5A 2YBYA 3O8EB 1Z92B 1HFIA 3CI0J 2BZMA 5HYTB 1ELVA 2IZ4A 3OXUD 2G7IA 2RLPA 2RLQA 1VVCA 2ERJA 1OJVA 2B5ID 2KMSA 4WJG2 1OK2A 1NWVA 2A55A 3M7PA 3GXEA 3ZLDA 3ERBA 3NFPI 1FBRA 3ZD2A 1HFHA 3OP8A 4N7EA 3ZD1A 4CSYA 2IZ3A 2QY0A 2RKZA 1H2PP 2CG6A 1TPNA 1RLHA 2W80A 4IGDA 1GPZA 1O9AA 1OJYA 2XRDA 4B2SA 1Q3XA 3WSXA 4LOSA 1H04P 2LOJA 1GKGA 3IX0A 2Y8RA 1PPQA 1SS2A 2XWJI 3T5OA 3NJAA 1H03P 4J38B 1TPMA 1SRZA 2MCYA 4AYIA 1U5MA 4C16A 5HYPA 4A5WB 2ZYCA 1QUBA 2XQWC 2I2LA 1G4GA 1E8BA 1QGBA 2WIIC 2YRAA 5JPMG 1CKLA 1ZJKA 2RL0A 1MD8A 4PZ5A 3MQLA 4LOTA 4AYDA 2UWNA 1G4FA 3KXVA 1E5GA 2XWBF 4JHSA 1TPGA 3FGTA 3RJ3D 4MUCA 3FGRA 4APLA 1E88A 2Y8TA 1GKNA 3INBC 3WSYA 2V8EA 4BWCA 1QO6A 2CKUA 3R62A 4ZH1D 1GHQB 3TVJA 3SW0X 2JGXA
chains in the Genus database with same CATH topology
1MD7A 2EC3A 1OK1A 2RKYA 4AYEA 4B2RA 3GOVA 1UOTP 4KKDA 3IU3I 4DJZA 3CALA 3KZJA 2CG7A 1OK3A 1VVDA 5HZPB 5I0QB 2JGWA 4F4OC 1OJWA 3ZRZA 2KRIA 2W81A 1H2QP 4YNXA 5HYUB 2JRAA 4ONTD 2O39C 2EHFA 1C1ZA 3EJHA 2MCZA 3L89M 4FXGG 1OK9A 1HCCA 3OEDC 5FO8C 4K12A 2XRBA 1LY2A 4AYMA 2YBYA 3O8EB 1Z92B 1HFIA 2BZMA 5HYTB 1ELVA 2IZ4A 3OXUD 2G7IA 2RLPA 2RLQA 1VVCA 2ERJA 1OJVA 2B5ID 2KMSA 4WJG2 1OK2A 1NWVA 2A55A 3M7PA 3GXEA 3ERBA 3NFPI 1FBRA 3ZD2A 1HFHA 3OP8A 3ZD1A 4CSYA 2IZ3A 2QY0A 2RKZA 1H2PP 2CG6A 1TPNA 2W80A 4IGDA 1GPZA 1O9AA 1OJYA 2XRDA 4B2SA 1Q3XA 4LOSA 1H04P 2LOJA 1GKGA 3IX0A 1PPQA 1SS2A 2XWJI 3T5OA 1H03P 4J38B 1TPMA 1SRZA 2MCYA 4AYIA 1U5MA 4C16A 5HYPA 4A5WB 1QUBA 2XQWC 1G4GA 1E8BA 1QGBA 2WIIC 2YRAA 5JPMG 1CKLA 1ZJKA 2RL0A 1MD8A 4PZ5A 3MQLA 4LOTA 4AYDA 2UWNA 1G4FA 3KXVA 1E5GA 2XWBF 4JHSA 1TPGA 3RJ3D 4MUCA 1E88A 1GKNA 3INBC 2V8EA 1QO6A 2CKUA 3R62A 4ZH1D 1GHQB 3TVJA 3SW0X 2JGXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MD7 A;  2EC3 A;  1OK1 A;  2RKY A;  4AYE A;  4B2R A;  3GOV A;  1UOT P;  4KKD A;  3IU3 I;  4DJZ A;  3CAL A;  3KZJ A;  2CG7 A;  1OK3 A;  1VVD A;  5HZP B;  5I0Q B;  2JGW A;  4F4O C;  1OJW A;  3ZRZ A;  2KRI A;  2W81 A;  1H2Q P;  4YNX A;  5HYU B;  2JRA A;  4ONT D;  2O39 C;  2EHF A;  1C1Z A;  3EJH A;  2MCZ A;  3L89 M;  4FXG G;  1OK9 A;  1HCC A;  3OED C;  5FO8 C;  4K12 A;  2XRB A;  1LY2 A;  4AYM A;  2YBY A;  3O8E B;  1Z92 B;  1HFI A;  2BZM A;  5HYT B;  1ELV A;  2IZ4 A;  3OXU D;  2G7I A;  2RLP A;  2RLQ A;  1VVC A;  2ERJ A;  1OJV A;  2B5I D;  2KMS A;  4WJG 2;  1OK2 A;  1NWV A;  2A55 A;  3M7P A;  3GXE A;  3ERB A;  3NFP I;  1FBR A;  3ZD2 A;  1HFH A;  3OP8 A;  3ZD1 A;  4CSY A;  2IZ3 A;  2QY0 A;  2RKZ A;  1H2P P;  2CG6 A;  1TPN A;  2W80 A;  4IGD A;  1GPZ A;  1O9A A;  1OJY A;  2XRD A;  4B2S A;  1Q3X A;  4LOS A;  1H04 P;  2LOJ A;  1GKG A;  3IX0 A;  1PPQ A;  1SS2 A;  2XWJ I;  3T5O A;  1H03 P;  4J38 B;  1TPM A;  1SRZ A;  2MCY A;  4AYI A;  1U5M A;  4C16 A;  5HYP A;  4A5W B;  1QUB A;  2XQW C;  1G4G A;  1E8B A;  1QGB A;  2WII C;  2YRA A;  5JPM G;  1CKL A;  1ZJK A;  2RL0 A;  1MD8 A;  4PZ5 A;  3MQL A;  4LOT A;  4AYD A;  2UWN A;  1G4F A;  3KXV A;  1E5G A;  2XWB F;  4JHS A;  1TPG A;  3RJ3 D;  4MUC A;  1E88 A;  1GKN A;  3INB C;  2V8E A;  1QO6 A;  2CKU A;  3R62 A;  4ZH1 D;  1GHQ B;  3TVJ A;  3SW0 X;  2JGX A; 
#chains in the Genus database with same CATH topology
 1MD7 A;  2EC3 A;  1OK1 A;  2X2Z A;  2RKY A;  4AYE A;  4B2R A;  3GOV A;  3K3T A;  1UOT P;  3F6K A;  4PO7 A;  2Y8S A;  4KKD A;  3IU3 I;  4DJZ A;  3CAL A;  5DN4 A;  3ZLE A;  3KZJ A;  2CG7 A;  4YIZ A;  1OK3 A;  1VVD A;  5HZP B;  5I0Q B;  2JGW A;  4F4O C;  1OJW A;  3ZRZ A;  2KRI A;  2W81 A;  1H2Q P;  4YNX A;  5HYU B;  2JRA A;  4ONT D;  2O39 C;  3VWO A;  2EHF A;  1C1Z A;  3EJH A;  2MCZ A;  3L89 M;  4FXG G;  1OK9 A;  1HCC A;  3OED C;  5FO8 C;  4K12 A;  2XRB A;  1LY2 A;  4MSL A;  4AYM A;  5DN5 A;  2YBY A;  3O8E B;  1Z92 B;  1HFI A;  3CI0 J;  2BZM A;  5HYT B;  1ELV A;  2IZ4 A;  3OXU D;  2G7I A;  2RLP A;  2RLQ A;  1VVC A;  2ERJ A;  1OJV A;  2B5I D;  2KMS A;  4WJG 2;  1OK2 A;  1NWV A;  2A55 A;  3M7P A;  3GXE A;  3ZLD A;  3ERB A;  3NFP I;  1FBR A;  3ZD2 A;  1HFH A;  3OP8 A;  4N7E A;  3ZD1 A;  4CSY A;  2IZ3 A;  2QY0 A;  2RKZ A;  1H2P P;  2CG6 A;  1TPN A;  1RLH A;  2W80 A;  4IGD A;  1GPZ A;  1O9A A;  1OJY A;  2XRD A;  4B2S A;  1Q3X A;  3WSX A;  4LOS A;  1H04 P;  2LOJ A;  1GKG A;  3IX0 A;  2Y8R A;  1PPQ A;  1SS2 A;  2XWJ I;  3T5O A;  3NJA A;  1H03 P;  4J38 B;  1TPM A;  1SRZ A;  2MCY A;  4AYI A;  1U5M A;  4C16 A;  5HYP A;  4A5W B;  2ZYC A;  1QUB A;  2XQW C;  2I2L A;  1G4G A;  1E8B A;  1QGB A;  2WII C;  2YRA A;  5JPM G;  1CKL A;  1ZJK A;  2RL0 A;  1MD8 A;  4PZ5 A;  3MQL A;  4LOT A;  4AYD A;  2UWN A;  1G4F A;  3KXV A;  1E5G A;  2XWB F;  4JHS A;  1TPG A;  3FGT A;  3RJ3 D;  4MUC A;  3FGR A;  4APL A;  1E88 A;  2Y8T A;  1GKN A;  3INB C;  3WSY A;  2V8E A;  4BWC A;  1QO6 A;  2CKU A;  3R62 A;  4ZH1 D;  1GHQ B;  3TVJ A;  3SW0 X;  2JGX A; 
#chains in the Genus database with same CATH homology
 1MD7 A;  2EC3 A;  1OK1 A;  2RKY A;  4AYE A;  4B2R A;  3GOV A;  1UOT P;  4KKD A;  3IU3 I;  4DJZ A;  3CAL A;  3KZJ A;  2CG7 A;  1OK3 A;  1VVD A;  5HZP B;  5I0Q B;  2JGW A;  4F4O C;  1OJW A;  3ZRZ A;  2KRI A;  2W81 A;  1H2Q P;  4YNX A;  5HYU B;  2JRA A;  4ONT D;  2O39 C;  2EHF A;  1C1Z A;  3EJH A;  2MCZ A;  3L89 M;  4FXG G;  1OK9 A;  1HCC A;  3OED C;  5FO8 C;  4K12 A;  2XRB A;  1LY2 A;  4AYM A;  2YBY A;  3O8E B;  1Z92 B;  1HFI A;  2BZM A;  5HYT B;  1ELV A;  2IZ4 A;  3OXU D;  2G7I A;  2RLP A;  2RLQ A;  1VVC A;  2ERJ A;  1OJV A;  2B5I D;  2KMS A;  4WJG 2;  1OK2 A;  1NWV A;  2A55 A;  3M7P A;  3GXE A;  3ERB A;  3NFP I;  1FBR A;  3ZD2 A;  1HFH A;  3OP8 A;  3ZD1 A;  4CSY A;  2IZ3 A;  2QY0 A;  2RKZ A;  1H2P P;  2CG6 A;  1TPN A;  2W80 A;  4IGD A;  1GPZ A;  1O9A A;  1OJY A;  2XRD A;  4B2S A;  1Q3X A;  4LOS A;  1H04 P;  2LOJ A;  1GKG A;  3IX0 A;  1PPQ A;  1SS2 A;  2XWJ I;  3T5O A;  1H03 P;  4J38 B;  1TPM A;  1SRZ A;  2MCY A;  4AYI A;  1U5M A;  4C16 A;  5HYP A;  4A5W B;  1QUB A;  2XQW C;  1G4G A;  1E8B A;  1QGB A;  2WII C;  2YRA A;  5JPM G;  1CKL A;  1ZJK A;  2RL0 A;  1MD8 A;  4PZ5 A;  3MQL A;  4LOT A;  4AYD A;  2UWN A;  1G4F A;  3KXV A;  1E5G A;  2XWB F;  4JHS A;  1TPG A;  3RJ3 D;  4MUC A;  1E88 A;  1GKN A;  3INB C;  2V8E A;  1QO6 A;  2CKU A;  3R62 A;  4ZH1 D;  1GHQ B;  3TVJ A;  3SW0 X;  2JGX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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