1CNUA

Phosphorylated actophorin from acantamoeba polyphaga
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
133
structure length
133
Chain Sequence
GIAVSDDCVQKFNELKLGHQHRYVTFKMNASNTEVVVEHVGGPNATYEDFKSQLPERDCRYAIFDYEFQVDGGQRNKITFILWAPDSAPIKSKMMYTSTKDSIKKKLVGIQVEVQATDAAEISEDAVSERAKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Interaction of actin monomers with Acanthamoeba actophorin (ADF/cofilin) and profilin.
pubmed doi rcsb
molecule tags Contractile
source organism Acanthamoeba polyphaga
molecule keywords ACTOPHORIN
total genus 39
structure length 133
sequence length 133
ec nomenclature
pdb deposition date 1999-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1cnuA00
1C0GS 4KEDA 2XFAA 4LIZA 2NUTA 2XF1A 2VACA 3CIPG 2FF6G 2D8BA 4PKGG 4S10C 3EH1A 5KYXB 1H1VG 2MP4A 1M4JA 1RGIG 5DD2A 3EGXA 1CNUA 1F7SA 3L50A 1TMWA 1M2OA 1P8ZG 3A5MS 3EFOA 1YAGG 5HVKD 1M2VA 2LXXA 1QPVA 1PCXA 2LJ8A 1Q8XA 4JD2H 4PKIG 1D4XG 3FG7A 3CJCG 1PD1A 1T2LA 1YVNG 1WNJA 2VIKA 1WFSA 1COFA 3FFNA 1HQZ1 3FG6A 3Q2BA 5KYYB 5KYUB 2W0IA 4CBXG 1TVJA 5FAEA 5HVKB 4BEX1 1SVRA 2NUPB 1WM4A 3EG9A 1EQYS 2QTVA 5KYWA 1X67A 3CJBG 3EGDA 1NM1G 2KVKA 2HD7A 2L72A 1T44G 1DEJS 1T3XA 1AHQA 2FH3A 2NUTB 3TU5B 4CBWG 1P8XA 1C0FS 5FAFA 1SVQA 3A5LS 2FH1A 1UDMA 5KYUA 1AK6A 5KYXA 1MDUA 4PKHB 3EGXB 1V6FA 1VKKA 3EH2A 5L6WC 1NMDG 1M2VB 1NPHA 3A5NS 2FF3A 5IVUA 2I2QA 2LLFA 2MV2A 1Q8GA 1T3YA 1ESVS 2FGHA 2MOTA 3DAWB 4Z94G 5KYNA 2VILA 1AK7A 5KYYA 3A5OS 5A1MA 3FFKA 1NLVG 3CI5G 1KCQA 1PD0A 1D0NA 1VFQA 2FH2A 3EG9B 2NUPA 5KYWB 4KEFA 4KEEA 1CFYA 3EFOB 3EGDB 1SVYA 2FH4A 1JHWA 1J72A 4CBUG
chains in the Genus database with same CATH superfamily
1C0GS 4KEDA 2XFAA 4LIZA 2NUTA 2XF1A 2VACA 3CIPG 2FF6G 2D8BA 4PKGG 4S10C 3EH1A 5KYXB 1H1VG 2MP4A 1M4JA 1RGIG 5DD2A 3EGXA 1CNUA 1F7SA 3L50A 1TMWA 1M2OA 1P8ZG 3A5MS 3EFOA 1YAGG 5HVKD 1M2VA 2LXXA 1QPVA 1PCXA 2LJ8A 1Q8XA 4JD2H 4PKIG 1D4XG 3FG7A 3CJCG 1PD1A 1T2LA 1YVNG 1WNJA 2VIKA 1WFSA 1COFA 3FFNA 1HQZ1 3FG6A 3Q2BA 5KYYB 5KYUB 2W0IA 4CBXG 1TVJA 5FAEA 5HVKB 4BEX1 1SVRA 2NUPB 1WM4A 3EG9A 1EQYS 2QTVA 5KYWA 1X67A 3CJBG 3EGDA 1NM1G 2KVKA 2HD7A 2L72A 1T44G 1DEJS 1T3XA 1AHQA 2FH3A 2NUTB 3TU5B 4CBWG 1P8XA 1C0FS 5FAFA 1SVQA 3A5LS 2FH1A 1UDMA 5KYUA 3DA7A 1AK6A 5KYXA 1MDUA 4PKHB 3EGXB 1V6FA 1VKKA 3EH2A 5L6WC 1NMDG 1M2VB 1NPHA 3A5NS 2FF3A 5IVUA 2I2QA 2LLFA 2MV2A 1Q8GA 1T3YA 1ESVS 2FGHA 2MOTA 3DAWB 4Z94G 5KYNA 2VILA 1AK7A 5KYYA 3A5OS 5A1MA 3FFKA 1NLVG 3CI5G 1KCQA 1PD0A 1D0NA 1VFQA 2FH2A 3EG9B 2NUPA 5KYWB 4KEFA 4KEEA 1CFYA 3EFOB 3EGDB 1SVYA 2FH4A 1JHWA 1J72A 4CBUG
chains in the Genus database with same CATH topology
1C0GS 4KEDA 2XFAA 4LIZA 2NUTA 2XF1A 2VACA 3CIPG 2FF6G 2D8BA 4PKGG 4S10C 3EH1A 5KYXB 1H1VG 2MP4A 1M4JA 1RGIG 5DD2A 3EGXA 1CNUA 1F7SA 3L50A 1TMWA 1M2OA 1P8ZG 3A5MS 3EFOA 1YAGG 5HVKD 1M2VA 2LXXA 1QPVA 1PCXA 2LJ8A 1Q8XA 4JD2H 4PKIG 1D4XG 3FG7A 3CJCG 1PD1A 1T2LA 1YVNG 1WNJA 2VIKA 1WFSA 1COFA 3FFNA 1HQZ1 3FG6A 3Q2BA 5KYYB 5KYUB 2W0IA 4CBXG 1TVJA 5FAEA 5HVKB 4BEX1 1SVRA 2NUPB 1WM4A 3EG9A 1EQYS 2QTVA 5KYWA 1X67A 3CJBG 3EGDA 1NM1G 2KVKA 2HD7A 2L72A 1T44G 1DEJS 1T3XA 1AHQA 2FH3A 2NUTB 3TU5B 4CBWG 1P8XA 1C0FS 5FAFA 1SVQA 3A5LS 2FH1A 1UDMA 5KYUA 3DA7A 1AK6A 5KYXA 1MDUA 4PKHB 3EGXB 1V6FA 1VKKA 3EH2A 5L6WC 1NMDG 1M2VB 1NPHA 3A5NS 2FF3A 5IVUA 2I2QA 2LLFA 2MV2A 1Q8GA 1T3YA 1ESVS 2FGHA 2MOTA 3DAWB 4Z94G 5KYNA 2VILA 1AK7A 5KYYA 3A5OS 5A1MA 3FFKA 1NLVG 3CI5G 1KCQA 1PD0A 1D0NA 1VFQA 2FH2A 3EG9B 2NUPA 5KYWB 4KEFA 4KEEA 1CFYA 3EFOB 3EGDB 1SVYA 2FH4A 1JHWA 1J72A 4CBUG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1C0G S;  4KED A;  2XFA A;  4LIZ A;  2NUT A;  2XF1 A;  2VAC A;  3CIP G;  2FF6 G;  2D8B A;  4PKG G;  4S10 C;  3EH1 A;  5KYX B;  1H1V G;  2MP4 A;  1M4J A;  1RGI G;  5DD2 A;  3EGX A;  1CNU A;  1F7S A;  3L50 A;  1TMW A;  1M2O A;  1P8Z G;  3A5M S;  3EFO A;  1YAG G;  5HVK D;  1M2V A;  2LXX A;  1QPV A;  1PCX A;  2LJ8 A;  1Q8X A;  4JD2 H;  4PKI G;  1D4X G;  3FG7 A;  3CJC G;  1PD1 A;  1T2L A;  1YVN G;  1WNJ A;  2VIK A;  1WFS A;  1COF A;  3FFN A;  1HQZ 1;  3FG6 A;  3Q2B A;  5KYY B;  5KYU B;  2W0I A;  4CBX G;  1TVJ A;  5FAE A;  5HVK B;  4BEX 1;  1SVR A;  2NUP B;  1WM4 A;  3EG9 A;  1EQY S;  2QTV A;  5KYW A;  1X67 A;  3CJB G;  3EGD A;  1NM1 G;  2KVK A;  2HD7 A;  2L72 A;  1T44 G;  1DEJ S;  1T3X A;  1AHQ A;  2FH3 A;  2NUT B;  3TU5 B;  4CBW G;  1P8X A;  1C0F S;  5FAF A;  1SVQ A;  3A5L S;  2FH1 A;  1UDM A;  5KYU A;  1AK6 A;  5KYX A;  1MDU A;  4PKH B;  3EGX B;  1V6F A;  1VKK A;  3EH2 A;  5L6W C;  1NMD G;  1M2V B;  1NPH A;  3A5N S;  2FF3 A;  5IVU A;  2I2Q A;  2LLF A;  2MV2 A;  1Q8G A;  1T3Y A;  1ESV S;  2FGH A;  2MOT A;  3DAW B;  4Z94 G;  5KYN A;  2VIL A;  1AK7 A;  5KYY A;  3A5O S;  5A1M A;  3FFK A;  1NLV G;  3CI5 G;  1KCQ A;  1PD0 A;  1D0N A;  1VFQ A;  2FH2 A;  3EG9 B;  2NUP A;  5KYW B;  4KEF A;  4KEE A;  1CFY A;  3EFO B;  3EGD B;  1SVY A;  2FH4 A;  1JHW A;  1J72 A;  4CBU G; 
#chains in the Genus database with same CATH topology
 1C0G S;  4KED A;  2XFA A;  4LIZ A;  2NUT A;  2XF1 A;  2VAC A;  3CIP G;  2FF6 G;  2D8B A;  4PKG G;  4S10 C;  3EH1 A;  5KYX B;  1H1V G;  2MP4 A;  1M4J A;  1RGI G;  5DD2 A;  3EGX A;  1CNU A;  1F7S A;  3L50 A;  1TMW A;  1M2O A;  1P8Z G;  3A5M S;  3EFO A;  1YAG G;  5HVK D;  1M2V A;  2LXX A;  1QPV A;  1PCX A;  2LJ8 A;  1Q8X A;  4JD2 H;  4PKI G;  1D4X G;  3FG7 A;  3CJC G;  1PD1 A;  1T2L A;  1YVN G;  1WNJ A;  2VIK A;  1WFS A;  1COF A;  3FFN A;  1HQZ 1;  3FG6 A;  3Q2B A;  5KYY B;  5KYU B;  2W0I A;  4CBX G;  1TVJ A;  5FAE A;  5HVK B;  4BEX 1;  1SVR A;  2NUP B;  1WM4 A;  3EG9 A;  1EQY S;  2QTV A;  5KYW A;  1X67 A;  3CJB G;  3EGD A;  1NM1 G;  2KVK A;  2HD7 A;  2L72 A;  1T44 G;  1DEJ S;  1T3X A;  1AHQ A;  2FH3 A;  2NUT B;  3TU5 B;  4CBW G;  1P8X A;  1C0F S;  5FAF A;  1SVQ A;  3A5L S;  2FH1 A;  1UDM A;  5KYU A;  3DA7 A;  1AK6 A;  5KYX A;  1MDU A;  4PKH B;  3EGX B;  1V6F A;  1VKK A;  3EH2 A;  5L6W C;  1NMD G;  1M2V B;  1NPH A;  3A5N S;  2FF3 A;  5IVU A;  2I2Q A;  2LLF A;  2MV2 A;  1Q8G A;  1T3Y A;  1ESV S;  2FGH A;  2MOT A;  3DAW B;  4Z94 G;  5KYN A;  2VIL A;  1AK7 A;  5KYY A;  3A5O S;  5A1M A;  3FFK A;  1NLV G;  3CI5 G;  1KCQ A;  1PD0 A;  1D0N A;  1VFQ A;  2FH2 A;  3EG9 B;  2NUP A;  5KYW B;  4KEF A;  4KEE A;  1CFY A;  3EFO B;  3EGD B;  1SVY A;  2FH4 A;  1JHW A;  1J72 A;  4CBU G; 
#chains in the Genus database with same CATH homology
 1C0G S;  4KED A;  2XFA A;  4LIZ A;  2NUT A;  2XF1 A;  2VAC A;  3CIP G;  2FF6 G;  2D8B A;  4PKG G;  4S10 C;  3EH1 A;  5KYX B;  1H1V G;  2MP4 A;  1M4J A;  1RGI G;  5DD2 A;  3EGX A;  1CNU A;  1F7S A;  3L50 A;  1TMW A;  1M2O A;  1P8Z G;  3A5M S;  3EFO A;  1YAG G;  5HVK D;  1M2V A;  2LXX A;  1QPV A;  1PCX A;  2LJ8 A;  1Q8X A;  4JD2 H;  4PKI G;  1D4X G;  3FG7 A;  3CJC G;  1PD1 A;  1T2L A;  1YVN G;  1WNJ A;  2VIK A;  1WFS A;  1COF A;  3FFN A;  1HQZ 1;  3FG6 A;  3Q2B A;  5KYY B;  5KYU B;  2W0I A;  4CBX G;  1TVJ A;  5FAE A;  5HVK B;  4BEX 1;  1SVR A;  2NUP B;  1WM4 A;  3EG9 A;  1EQY S;  2QTV A;  5KYW A;  1X67 A;  3CJB G;  3EGD A;  1NM1 G;  2KVK A;  2HD7 A;  2L72 A;  1T44 G;  1DEJ S;  1T3X A;  1AHQ A;  2FH3 A;  2NUT B;  3TU5 B;  4CBW G;  1P8X A;  1C0F S;  5FAF A;  1SVQ A;  3A5L S;  2FH1 A;  1UDM A;  5KYU A;  3DA7 A;  1AK6 A;  5KYX A;  1MDU A;  4PKH B;  3EGX B;  1V6F A;  1VKK A;  3EH2 A;  5L6W C;  1NMD G;  1M2V B;  1NPH A;  3A5N S;  2FF3 A;  5IVU A;  2I2Q A;  2LLF A;  2MV2 A;  1Q8G A;  1T3Y A;  1ESV S;  2FGH A;  2MOT A;  3DAW B;  4Z94 G;  5KYN A;  2VIL A;  1AK7 A;  5KYY A;  3A5O S;  5A1M A;  3FFK A;  1NLV G;  3CI5 G;  1KCQ A;  1PD0 A;  1D0N A;  1VFQ A;  2FH2 A;  3EG9 B;  2NUP A;  5KYW B;  4KEF A;  4KEE A;  1CFY A;  3EFO B;  3EGD B;  1SVY A;  2FH4 A;  1JHW A;  1J72 A;  4CBU G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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