1CY5A

Crystal structure of the apaf-1 card
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
92
structure length
92
Chain Sequence
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Apoptosis
molecule keywords PROTEIN (APOPTOTIC PROTEASE ACTIVATING FACTOR 1)
total genus 34
structure length 92
sequence length 92
ec nomenclature
pdb deposition date 1999-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00619 CARD Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 1cy5A00
2DBDA 3J63A 4A2WA 1E41A 4M9ZA 2D96A 2MPCA 4EWIA 3YGSP 2YQFA 1A1WA 1NGRA 2DBHA 2MS8A 3CL3A 3KATA 1D2ZA 2VGQA 1ICHA 2YVIA 3J6JA 4JQWA 2N7ZA 2YU0A 3QF2A 4I16A 4O9FA 1DDFA 2N00A 2HM2Q 4NQKA 2DBFA 1CY5A 3MOPK 3LQRA 4FH0A 2N83A 3EZQB 4N1JA 4D8OA 4P4HI 2L9MA 2N80A 2MS7A 4F44A 2OF5A 4IZ5E 3YGSC 1C15A 2LWDA 2N97A 2DO9A 4RHWA 3LQQA 2LWEA 3CRDA 1WH4A 4IZ7B 4P4HA 1UCPA 1WMGA 4E9MA 4N1LA 1Z6TA 2F1SA 3MOPA 1YGOA 4O6XA 4JUPA 2M5VA 2KN6A 1CWWA 2GF5A 2A5YB 1WXPA 4F42A 2L6AA 2OF5H 2BBZA 1N3KA 2G7RA 1DGNA 4LWDA 2N1FA 2P1HA 4RHWE 2O71A 4IZAB 4ZBWA 4A2QA 2IB1A 1PN5A 4DWNA 1A1ZA 3T6PA 2KM6A 2LS7A 2A9IA 4UZ0A 4M9XA 4N1KA 2NSNA 3MOPG 2MB9A 4M9SA 2YGSA 2DBGA 1FADA 1E3YA 1D2ZB 2B1WA 4O7QA 4O9LA 2MN4A 2BBRA 4QOBA 2NAQA 3EZQA 2NZ7A
chains in the Genus database with same CATH superfamily
2DBDA 3J63A 4A2WA 1E41A 4M9ZA 2D96A 2MPCA 4EWIA 3YGSP 2YQFA 1A1WA 1NGRA 2DBHA 2MS8A 3CL3A 3KATA 1D2ZA 2VGQA 1ICHA 2YVIA 3J6JA 4JQWA 2N7ZA 2YU0A 3QF2A 4I16A 4O9FA 1DDFA 2N00A 2HM2Q 4NQKA 2DBFA 1CY5A 3MOPK 3LQRA 4FH0A 2N83A 3EZQB 4N1JA 4D8OA 4P4HI 2L9MA 2N80A 2MS7A 4F44A 2OF5A 4IZ5E 3YGSC 1C15A 2LWDA 2N97A 2DO9A 4RHWA 3LQQA 2LWEA 2XV9A 3CRDA 1WH4A 4IZ7B 4P4HA 1UCPA 1WMGA 4E9MA 4N1LA 1Z6TA 2F1SA 3MOPA 1YGOA 4O6XA 4JUPA 2M5VA 2KN6A 2MJMA 1CWWA 2GF5A 2A5YB 1WXPA 4F42A 2L6AA 2OF5H 2BBZA 1N3KA 2G7RA 1DGNA 4LWDA 2N1FA 2P1HA 4RHWE 2O71A 4IZAB 4ZBWA 4A2QA 2IB1A 1PN5A 4DWNA 1A1ZA 3T6PA 2KM6A 2LS7A 2A9IA 4UZ0A 4M9XA 4N1KA 2NSNA 3MOPG 2MB9A 4M9SA 2YGSA 2DBGA 1FADA 1E3YA 1D2ZB 2B1WA 4O7QA 4O9LA 2MN4A 2BBRA 4QOBA 2NAQA 3EZQA 2NZ7A
chains in the Genus database with same CATH topology
2DBDA 3J63A 4A2WA 1E41A 4M9ZA 2D96A 2MPCA 4EWIA 3YGSP 2YQFA 1A1WA 1NGRA 2DBHA 2MS8A 3CL3A 3KATA 1D2ZA 2VGQA 1ICHA 2YVIA 3J6JA 4JQWA 2N7ZA 2YU0A 3QF2A 4I16A 4O9FA 1DDFA 2N00A 2HM2Q 4NQKA 2DBFA 1CY5A 3MOPK 3LQRA 4FH0A 2N83A 3EZQB 4N1JA 4D8OA 4P4HI 2L9MA 2N80A 2MS7A 4F44A 2OF5A 4IZ5E 3YGSC 1C15A 2LWDA 2N97A 2DO9A 4RHWA 3LQQA 2LWEA 2XV9A 3CRDA 1WH4A 4IZ7B 4P4HA 1UCPA 1WMGA 4E9MA 4N1LA 1Z6TA 2F1SA 3MOPA 1YGOA 4O6XA 4JUPA 2M5VA 2KN6A 2MJMA 1CWWA 2GF5A 2A5YB 1WXPA 4F42A 2L6AA 2OF5H 2BBZA 1N3KA 2G7RA 1DGNA 4LWDA 2N1FA 2P1HA 4RHWE 2O71A 4IZAB 4ZBWA 4A2QA 2IB1A 1PN5A 4DWNA 1A1ZA 3T6PA 2KM6A 2LS7A 2A9IA 4UZ0A 4M9XA 4N1KA 2NSNA 3MOPG 2MB9A 4M9SA 2YGSA 2DBGA 1FADA 1E3YA 1D2ZB 2B1WA 4O7QA 4O9LA 2MN4A 2BBRA 4QOBA 2NAQA 3EZQA 2NZ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DBD A;  3J63 A;  4A2W A;  1E41 A;  4M9Z A;  2D96 A;  2MPC A;  4EWI A;  3YGS P;  2YQF A;  1A1W A;  1NGR A;  2DBH A;  2MS8 A;  3CL3 A;  3KAT A;  1D2Z A;  2VGQ A;  1ICH A;  2YVI A;  3J6J A;  4JQW A;  2N7Z A;  2YU0 A;  3QF2 A;  4I16 A;  4O9F A;  1DDF A;  2N00 A;  2HM2 Q;  4NQK A;  2DBF A;  1CY5 A;  3MOP K;  3LQR A;  4FH0 A;  2N83 A;  3EZQ B;  4N1J A;  4D8O A;  4P4H I;  2L9M A;  2N80 A;  2MS7 A;  4F44 A;  2OF5 A;  4IZ5 E;  3YGS C;  1C15 A;  2LWD A;  2N97 A;  2DO9 A;  4RHW A;  3LQQ A;  2LWE A;  3CRD A;  1WH4 A;  4IZ7 B;  4P4H A;  1UCP A;  1WMG A;  4E9M A;  4N1L A;  1Z6T A;  2F1S A;  3MOP A;  1YGO A;  4O6X A;  4JUP A;  2M5V A;  2KN6 A;  1CWW A;  2GF5 A;  2A5Y B;  1WXP A;  4F42 A;  2L6A A;  2OF5 H;  2BBZ A;  1N3K A;  2G7R A;  1DGN A;  4LWD A;  2N1F A;  2P1H A;  4RHW E;  2O71 A;  4IZA B;  4ZBW A;  4A2Q A;  2IB1 A;  1PN5 A;  4DWN A;  1A1Z A;  3T6P A;  2KM6 A;  2LS7 A;  2A9I A;  4UZ0 A;  4M9X A;  4N1K A;  2NSN A;  3MOP G;  2MB9 A;  4M9S A;  2YGS A;  2DBG A;  1FAD A;  1E3Y A;  1D2Z B;  2B1W A;  4O7Q A;  4O9L A;  2MN4 A;  2BBR A;  4QOB A;  2NAQ A;  3EZQ A;  2NZ7 A; 
#chains in the Genus database with same CATH topology
 2DBD A;  3J63 A;  4A2W A;  1E41 A;  4M9Z A;  2D96 A;  2MPC A;  4EWI A;  3YGS P;  2YQF A;  1A1W A;  1NGR A;  2DBH A;  2MS8 A;  3CL3 A;  3KAT A;  1D2Z A;  2VGQ A;  1ICH A;  2YVI A;  3J6J A;  4JQW A;  2N7Z A;  2YU0 A;  3QF2 A;  4I16 A;  4O9F A;  1DDF A;  2N00 A;  2HM2 Q;  4NQK A;  2DBF A;  1CY5 A;  3MOP K;  3LQR A;  4FH0 A;  2N83 A;  3EZQ B;  4N1J A;  4D8O A;  4P4H I;  2L9M A;  2N80 A;  2MS7 A;  4F44 A;  2OF5 A;  4IZ5 E;  3YGS C;  1C15 A;  2LWD A;  2N97 A;  2DO9 A;  4RHW A;  3LQQ A;  2LWE A;  2XV9 A;  3CRD A;  1WH4 A;  4IZ7 B;  4P4H A;  1UCP A;  1WMG A;  4E9M A;  4N1L A;  1Z6T A;  2F1S A;  3MOP A;  1YGO A;  4O6X A;  4JUP A;  2M5V A;  2KN6 A;  2MJM A;  1CWW A;  2GF5 A;  2A5Y B;  1WXP A;  4F42 A;  2L6A A;  2OF5 H;  2BBZ A;  1N3K A;  2G7R A;  1DGN A;  4LWD A;  2N1F A;  2P1H A;  4RHW E;  2O71 A;  4IZA B;  4ZBW A;  4A2Q A;  2IB1 A;  1PN5 A;  4DWN A;  1A1Z A;  3T6P A;  2KM6 A;  2LS7 A;  2A9I A;  4UZ0 A;  4M9X A;  4N1K A;  2NSN A;  3MOP G;  2MB9 A;  4M9S A;  2YGS A;  2DBG A;  1FAD A;  1E3Y A;  1D2Z B;  2B1W A;  4O7Q A;  4O9L A;  2MN4 A;  2BBR A;  4QOB A;  2NAQ A;  3EZQ A;  2NZ7 A; 
#chains in the Genus database with same CATH homology
 2DBD A;  3J63 A;  4A2W A;  1E41 A;  4M9Z A;  2D96 A;  2MPC A;  4EWI A;  3YGS P;  2YQF A;  1A1W A;  1NGR A;  2DBH A;  2MS8 A;  3CL3 A;  3KAT A;  1D2Z A;  2VGQ A;  1ICH A;  2YVI A;  3J6J A;  4JQW A;  2N7Z A;  2YU0 A;  3QF2 A;  4I16 A;  4O9F A;  1DDF A;  2N00 A;  2HM2 Q;  4NQK A;  2DBF A;  1CY5 A;  3MOP K;  3LQR A;  4FH0 A;  2N83 A;  3EZQ B;  4N1J A;  4D8O A;  4P4H I;  2L9M A;  2N80 A;  2MS7 A;  4F44 A;  2OF5 A;  4IZ5 E;  3YGS C;  1C15 A;  2LWD A;  2N97 A;  2DO9 A;  4RHW A;  3LQQ A;  2LWE A;  2XV9 A;  3CRD A;  1WH4 A;  4IZ7 B;  4P4H A;  1UCP A;  1WMG A;  4E9M A;  4N1L A;  1Z6T A;  2F1S A;  3MOP A;  1YGO A;  4O6X A;  4JUP A;  2M5V A;  2KN6 A;  2MJM A;  1CWW A;  2GF5 A;  2A5Y B;  1WXP A;  4F42 A;  2L6A A;  2OF5 H;  2BBZ A;  1N3K A;  2G7R A;  1DGN A;  4LWD A;  2N1F A;  2P1H A;  4RHW E;  2O71 A;  4IZA B;  4ZBW A;  4A2Q A;  2IB1 A;  1PN5 A;  4DWN A;  1A1Z A;  3T6P A;  2KM6 A;  2LS7 A;  2A9I A;  4UZ0 A;  4M9X A;  4N1K A;  2NSN A;  3MOP G;  2MB9 A;  4M9S A;  2YGS A;  2DBG A;  1FAD A;  1E3Y A;  1D2Z B;  2B1W A;  4O7Q A;  4O9L A;  2MN4 A;  2BBR A;  4QOB A;  2NAQ A;  3EZQ A;  2NZ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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