1CY5A

Crystal structure of the apaf-1 card
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
92
structure length
92
Chain Sequence
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Apoptosis
molecule keywords PROTEIN (APOPTOTIC PROTEASE ACTIVATING FACTOR 1)
total genus 34
structure length 92
sequence length 92
ec nomenclature
pdb deposition date 1999-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00619 CARD Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 1cy5A00
2MB9A 3J63A 2NAQA 1DDFA 3MOPK 4FH0A 2VGQA 2N7ZA 1DGNA 1ICHA 4LWDA 2HM2Q 4O6XA 4RHWA 2A5YB 4A2WA 2A9IA 4I16A 2G7RA 2DBFA 1NGRA 4E9MA 4M9ZA 1WXPA 2YU0A 2NSNA 4JQWA 4EWIA 3LQRA 4M9XA 2P1HA 2DO9A 3MOPG 3YGSC 2LWEA 2F1SA 2N97A 1PN5A 2BBZA 2OF5A 4QOBA 4A2QA 1CY5A 2GF5A 4N1LA 4JUPA 2O71A 1UCPA 2NZ7A 2MS8A 4IZAB 3EZQB 4N1KA 2L6AA 3YGSP 4IZ7B 4O9LA 2OF5H 3MOPA 1C15A 3KATA 4M9SA 1WMGA 2MPCA 3CRDA 2DBDA 2IB1A 1FADA 1E3YA 1A1ZA 1Z6TA 2KM6A 4IZ5E 1A1WA 2N83A 4O7QA 2KN6A 3LQQA 2LS7A 2DBGA 4D8OA 1CWWA 1N3KA 1D2ZA 3J6JA 2MN4A 3T6PA 2LWDA 2YGSA 4DWNA 4P4HI 2BBRA 4N1JA 4O9FA 1D2ZB 2N80A 4F42A 2MS7A 3EZQA 2DBHA 4P4HA 4RHWE 3CL3A 1YGOA 2B1WA 2N1FA 2YQFA 2YVIA 2L9MA 2N00A 2D96A 1E41A 4UZ0A 4NQKA 3QF2A 1WH4A 4ZBWA 2M5VA 4F44A
chains in the Genus database with same CATH superfamily
2MB9A 3J63A 2NAQA 1DDFA 3MOPK 4FH0A 2VGQA 2N7ZA 1DGNA 1ICHA 4LWDA 2HM2Q 4O6XA 4RHWA 2A5YB 4A2WA 2A9IA 4I16A 2G7RA 2DBFA 1NGRA 4E9MA 4M9ZA 1WXPA 2YU0A 2NSNA 4JQWA 4EWIA 3LQRA 4M9XA 2P1HA 2DO9A 3MOPG 3YGSC 2LWEA 2F1SA 2N97A 1PN5A 2BBZA 2OF5A 4QOBA 4A2QA 1CY5A 2GF5A 4N1LA 4JUPA 2O71A 1UCPA 2MJMA 2NZ7A 2MS8A 4IZAB 3EZQB 4N1KA 2L6AA 3YGSP 4IZ7B 4O9LA 2OF5H 3MOPA 1C15A 3KATA 4M9SA 1WMGA 2MPCA 3CRDA 2DBDA 2IB1A 1FADA 1E3YA 1A1ZA 1Z6TA 2KM6A 4IZ5E 1A1WA 2N83A 4O7QA 2KN6A 3LQQA 2LS7A 2DBGA 4D8OA 1CWWA 1N3KA 1D2ZA 3J6JA 2XV9A 2MN4A 3T6PA 2LWDA 2YGSA 4DWNA 4P4HI 2BBRA 4N1JA 4O9FA 1D2ZB 2N80A 4F42A 2MS7A 3EZQA 2DBHA 4P4HA 4RHWE 3CL3A 1YGOA 2B1WA 2N1FA 2YQFA 2YVIA 2L9MA 2N00A 2D96A 1E41A 4UZ0A 4NQKA 3QF2A 1WH4A 4ZBWA 2M5VA 4F44A
chains in the Genus database with same CATH topology
2MB9A 3J63A 2NAQA 1DDFA 3MOPK 4FH0A 2VGQA 2N7ZA 1DGNA 1ICHA 4LWDA 2HM2Q 4O6XA 4RHWA 2A5YB 4A2WA 2A9IA 4I16A 2G7RA 2DBFA 1NGRA 4E9MA 4M9ZA 1WXPA 2YU0A 2NSNA 4JQWA 4EWIA 3LQRA 4M9XA 2P1HA 2DO9A 3MOPG 3YGSC 2LWEA 2F1SA 2N97A 1PN5A 2BBZA 2OF5A 4QOBA 4A2QA 1CY5A 2GF5A 4N1LA 4JUPA 2O71A 1UCPA 2MJMA 2NZ7A 2MS8A 4IZAB 3EZQB 4N1KA 2L6AA 3YGSP 4IZ7B 4O9LA 2OF5H 3MOPA 1C15A 3KATA 4M9SA 1WMGA 2MPCA 3CRDA 2DBDA 2IB1A 1FADA 1E3YA 1A1ZA 1Z6TA 2KM6A 4IZ5E 1A1WA 2N83A 4O7QA 2KN6A 3LQQA 2LS7A 2DBGA 4D8OA 1CWWA 1N3KA 1D2ZA 3J6JA 2XV9A 2MN4A 3T6PA 2LWDA 2YGSA 4DWNA 4P4HI 2BBRA 4N1JA 4O9FA 1D2ZB 2N80A 4F42A 2MS7A 3EZQA 2DBHA 4P4HA 4RHWE 3CL3A 1YGOA 2B1WA 2N1FA 2YQFA 2YVIA 2L9MA 2N00A 2D96A 1E41A 4UZ0A 4NQKA 3QF2A 1WH4A 4ZBWA 2M5VA 4F44A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MB9 A;  3J63 A;  2NAQ A;  1DDF A;  3MOP K;  4FH0 A;  2VGQ A;  2N7Z A;  1DGN A;  1ICH A;  4LWD A;  2HM2 Q;  4O6X A;  4RHW A;  2A5Y B;  4A2W A;  2A9I A;  4I16 A;  2G7R A;  2DBF A;  1NGR A;  4E9M A;  4M9Z A;  1WXP A;  2YU0 A;  2NSN A;  4JQW A;  4EWI A;  3LQR A;  4M9X A;  2P1H A;  2DO9 A;  3MOP G;  3YGS C;  2LWE A;  2F1S A;  2N97 A;  1PN5 A;  2BBZ A;  2OF5 A;  4QOB A;  4A2Q A;  1CY5 A;  2GF5 A;  4N1L A;  4JUP A;  2O71 A;  1UCP A;  2NZ7 A;  2MS8 A;  4IZA B;  3EZQ B;  4N1K A;  2L6A A;  3YGS P;  4IZ7 B;  4O9L A;  2OF5 H;  3MOP A;  1C15 A;  3KAT A;  4M9S A;  1WMG A;  2MPC A;  3CRD A;  2DBD A;  2IB1 A;  1FAD A;  1E3Y A;  1A1Z A;  1Z6T A;  2KM6 A;  4IZ5 E;  1A1W A;  2N83 A;  4O7Q A;  2KN6 A;  3LQQ A;  2LS7 A;  2DBG A;  4D8O A;  1CWW A;  1N3K A;  1D2Z A;  3J6J A;  2MN4 A;  3T6P A;  2LWD A;  2YGS A;  4DWN A;  4P4H I;  2BBR A;  4N1J A;  4O9F A;  1D2Z B;  2N80 A;  4F42 A;  2MS7 A;  3EZQ A;  2DBH A;  4P4H A;  4RHW E;  3CL3 A;  1YGO A;  2B1W A;  2N1F A;  2YQF A;  2YVI A;  2L9M A;  2N00 A;  2D96 A;  1E41 A;  4UZ0 A;  4NQK A;  3QF2 A;  1WH4 A;  4ZBW A;  2M5V A;  4F44 A; 
#chains in the Genus database with same CATH topology
 2MB9 A;  3J63 A;  2NAQ A;  1DDF A;  3MOP K;  4FH0 A;  2VGQ A;  2N7Z A;  1DGN A;  1ICH A;  4LWD A;  2HM2 Q;  4O6X A;  4RHW A;  2A5Y B;  4A2W A;  2A9I A;  4I16 A;  2G7R A;  2DBF A;  1NGR A;  4E9M A;  4M9Z A;  1WXP A;  2YU0 A;  2NSN A;  4JQW A;  4EWI A;  3LQR A;  4M9X A;  2P1H A;  2DO9 A;  3MOP G;  3YGS C;  2LWE A;  2F1S A;  2N97 A;  1PN5 A;  2BBZ A;  2OF5 A;  4QOB A;  4A2Q A;  1CY5 A;  2GF5 A;  4N1L A;  4JUP A;  2O71 A;  1UCP A;  2MJM A;  2NZ7 A;  2MS8 A;  4IZA B;  3EZQ B;  4N1K A;  2L6A A;  3YGS P;  4IZ7 B;  4O9L A;  2OF5 H;  3MOP A;  1C15 A;  3KAT A;  4M9S A;  1WMG A;  2MPC A;  3CRD A;  2DBD A;  2IB1 A;  1FAD A;  1E3Y A;  1A1Z A;  1Z6T A;  2KM6 A;  4IZ5 E;  1A1W A;  2N83 A;  4O7Q A;  2KN6 A;  3LQQ A;  2LS7 A;  2DBG A;  4D8O A;  1CWW A;  1N3K A;  1D2Z A;  3J6J A;  2XV9 A;  2MN4 A;  3T6P A;  2LWD A;  2YGS A;  4DWN A;  4P4H I;  2BBR A;  4N1J A;  4O9F A;  1D2Z B;  2N80 A;  4F42 A;  2MS7 A;  3EZQ A;  2DBH A;  4P4H A;  4RHW E;  3CL3 A;  1YGO A;  2B1W A;  2N1F A;  2YQF A;  2YVI A;  2L9M A;  2N00 A;  2D96 A;  1E41 A;  4UZ0 A;  4NQK A;  3QF2 A;  1WH4 A;  4ZBW A;  2M5V A;  4F44 A; 
#chains in the Genus database with same CATH homology
 2MB9 A;  3J63 A;  2NAQ A;  1DDF A;  3MOP K;  4FH0 A;  2VGQ A;  2N7Z A;  1DGN A;  1ICH A;  4LWD A;  2HM2 Q;  4O6X A;  4RHW A;  2A5Y B;  4A2W A;  2A9I A;  4I16 A;  2G7R A;  2DBF A;  1NGR A;  4E9M A;  4M9Z A;  1WXP A;  2YU0 A;  2NSN A;  4JQW A;  4EWI A;  3LQR A;  4M9X A;  2P1H A;  2DO9 A;  3MOP G;  3YGS C;  2LWE A;  2F1S A;  2N97 A;  1PN5 A;  2BBZ A;  2OF5 A;  4QOB A;  4A2Q A;  1CY5 A;  2GF5 A;  4N1L A;  4JUP A;  2O71 A;  1UCP A;  2MJM A;  2NZ7 A;  2MS8 A;  4IZA B;  3EZQ B;  4N1K A;  2L6A A;  3YGS P;  4IZ7 B;  4O9L A;  2OF5 H;  3MOP A;  1C15 A;  3KAT A;  4M9S A;  1WMG A;  2MPC A;  3CRD A;  2DBD A;  2IB1 A;  1FAD A;  1E3Y A;  1A1Z A;  1Z6T A;  2KM6 A;  4IZ5 E;  1A1W A;  2N83 A;  4O7Q A;  2KN6 A;  3LQQ A;  2LS7 A;  2DBG A;  4D8O A;  1CWW A;  1N3K A;  1D2Z A;  3J6J A;  2XV9 A;  2MN4 A;  3T6P A;  2LWD A;  2YGS A;  4DWN A;  4P4H I;  2BBR A;  4N1J A;  4O9F A;  1D2Z B;  2N80 A;  4F42 A;  2MS7 A;  3EZQ A;  2DBH A;  4P4H A;  4RHW E;  3CL3 A;  1YGO A;  2B1W A;  2N1F A;  2YQF A;  2YVI A;  2L9M A;  2N00 A;  2D96 A;  1E41 A;  4UZ0 A;  4NQK A;  3QF2 A;  1WH4 A;  4ZBW A;  2M5V A;  4F44 A; 
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similar chains in the Genus database (?% sequence similarity)
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