1CZ4A

Nmr structure of vat-n: the n-terminal domain of vat (vcp-like atpase of thermoplasma)
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
185
structure length
185
Chain Sequence
MESNNGIILRVAEANSTDPGMSRVRLDESSRRLLDAEIGDVVEIEKVRKTVGRVYRARPEDENKGIVRIDSVMRNNCGASIGDKVKVRKVRTEIAKKVTLAPIIRKDQRLKFGEGIEEYVQRALIRRPMLEQDNISVPGLTLAGQTGLLFKVVKTLPSKVPVEIGEETKIEIREEPASEVLEEGG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The solution structure of VAT-N reveals a 'missing link' in the evolution of complex enzymes from a simple betaalphabetabeta element.
pubmed doi rcsb
molecule tags Hydrolase
source organism Thermoplasma acidophilum
molecule keywords VCP-LIKE ATPASE
total genus 24
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 1999-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1cz4A01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 1cz4A02
2NVXA 2E7ZA 2IV2X 2JA7A 3GTQA 3QC8A 2VPYA 1PT1A 1PPYA 1YLEA 2JA5A 2WB1A 4AYBA 3GTGA 3ML1A 4DMRA 1PYQA 2NAPA 3PLXB 3DMRA 2KI8A 4GA6A 4QIWA 3CQZA 1DMRA 1Y4ZA 1KQFA 5FTLA 2VPXA 1H5NA 2JIMA 1E32A 2VPZA 4AONB 1DMSA 1UHDA 4RV0A 1OGYA 4AZDA 1G8KA 1Y5IA 2JIPA 2JIRA 4C2MA 1CZ5A 1CZ4A 1PQHA 1CR5A 1I50A 1E18A 1QCSA 5GLFA 5FTKA 3QQ7A 2R93A 3H0GA 1K83A 1Q16A 1VC3B 3QWZA 5C18A 2E2HA 2VPWA 2C45A 3IR7A 5FTMA 2R92A 5EPPA 1AW8B 3IR6A 2PJHB 3HU1A 3GTPA 1H0HA 2V45A 1E61A 4AOKB 1PQFA 2E2IA 3FKIA 1TWGA 4AAYA 2NVYA 5FTNA 5DYGA 4CRYG 1TMOA 4CRZA 2EEOB 4KLNA 2JV2A 1I3QA 1ZC1A 1TWAA 1WCMA 2JIOA 2NYAA 2PMZA 5FTJA 3TIWA 3HU3A 2WAQA 2Y0SA 4KDLA 5C1BA 1TWCA 1R27A 3QQ8A 3GTKA 5B6CA 4KDIA 1G8JA 3HKZA 3GTOA 1S3SA 1SIWA 1FDOA 3GTLA 4KODA 1IW7D 1UHEA 2V3VA 1R9TA 2R7ZA 3IR5A 1Y1VA 1QDNA 2YU9A 1E60A 5T5MD 3CF2A 3GTJA 4D7ZB 2JA6A 4KO8A 2JIQA 5DYIA 2YUJA 2B63A 3GTMA 3O5AA 1PT0A 2VUMA 3TM7B 3OUGA 3HU2A 1E5VA 1TWHA 1AA6A 1Y1WA 5T5ID 4CS0A 1FDIA 1PYUB 1R7RA 1TWFA 1PQEA 1WLFA 1SFOA 1KQGA 4GA5A 2DMRA 1EU1A
chains in the Genus database with same CATH superfamily
2NVXA 3SUKA 2E7ZA 2IV2X 2JA7A 3GTQA 3QC8A 2VPYA 3X2JA 1PT1A 2Q1AX 3X2HA 5CCXA 1SMYD 1PPYA 1YLEA 5GLYA 2JA5A 2WB1A 2B25A 4UC4A 4AYBA 2A6ED 2ENGA 3M3GA 3SUMA 3GTGA 2XDPA 5CD1A 3ML1A 4DMRA 1PYQA 2GAEA 2NAPA 3ENGA 3PLXB 3DMRA 2KI8A 2G6GA 1HD5A 4GA6A 4L48A 4QIWA 3CQZA 1DMRA 1Y4ZA 1KQFA 5D6YA 1N10A 5FTLA 2VPXA 1H5NA 2JIMA 1E32A 2VPZA 4AONB 1DMSA 1UHDA 1YNJD 4RV0A 1OGYA 1YNND 3ZGZA 4AZDA 1G8KA 1Y5IA 2JIPA 5ERGB 4AS1A 2JIRA 4C2MA 1CZ5A 2Q1CX 1CZ4A 1PQHA 1CR5A 1I50A 1E18A 4JJOA 1QCSA 5GLFA 5FTKA 3QQ7A 3X2IA 2R93A 3BQBA 3H0GA 2QQRA 1K83A 1Q16A 3X2KA 4JS7A 3ZJUA 1VC3B 4ENGA 2YVLA 3CZBA 4FG4A 1WC2A 3QWZA 5C18A 2E2HA 2VPWA 2C45A 3IR7A 4CQNA 5FTMA 4ZM7A 2R92A 5EPPA 2PWYA 3FPRA 1AW8B 3IR6A 2PJHB 3HU1A 3GTPA 1H0HA 2LW6A 2V45A 5GM9A 1E61A 4AOKB 2QQSA 1PQFA 2E2IA 3ZJVA 2PI8A 3FKIA 5CCBA 1TWGA 1OA7A 2NVYA 2AE0X 4AAYA 5FTNA 5DYGA 4CRYG 1TMOA 2BH0A 2PJJA 4CRZA 3LGAA 2CW0D 2EEOB 4KLNA 2G5DA 2MM0A 2JV2A 2PICA 1I3QA 4FERA 1ZC1A 4JCWA 1TWAA 1WCMA 2JIOA 2NYAA 2PMZA 5FTJA 3TIWA 3HU3A 2Q18X 2WAQA 2Y0SA 3SULA 2KQAA 4KDLA 1OA9A 2A6HD 5C1BA 1TWCA 1I9GA 2O5JD 4AQ7A 1BW3A 1R27A 3X2MA 4FFTA 3QQ8A 3GTKA 3X2NA 5B6CA 4KDIA 1G8JA 3HKZA 2A68D 1S3SA 2HCZX 1FDOA 1SIWA 3GTLA 1L8FA 4KODA 3GTOA 2Q19X 1IW7D 3SUJA 3ZJTA 4FG2A 1UHEA 2V3VA 1R9TA 2R7ZA 3IR5A 1Y1VA 1QDNA 4NOHA 2GFAA 3X2LA 2YU9A 4ARIA 1E60A 2KY9A 5T5MD 2Q1DX 3CF2A 3GTJA 4D7ZB 2JA6A 4KO8A 2JIQA 5DYIA 2YUJA 2B63A 5D6XA 3GTMA 3O5AA 5D6WA 1PT0A 2BE5D 2VUMA 3TM7B 3OUGA 3HU2A 4JP6A 2GF7A 2MM2A 1BW4A 1E5VA 1TWHA 1AA6A 1Y1WA 3MB5A 5EQJB 1O54A 5T5ID 5GLXA 4ARCA 4CS0A 1FDIA 2A69D 1PYUB 1R7RA 1TWFA 3D30A 3X2PA 3FPUA 1PQEA 1WLFA 1SFOA 3X2GA 4FIBA 4AVRA 2PNWA 1KQGA 5H4UA 3X2OA 4GA5A 3FPTA 2DMRA 4JP7A 1ZYRD 1EU1A 3LHDA
chains in the Genus database with same CATH topology
2NVXA 2E7ZA 2IV2X 2JA7A 3GTQA 3QC8A 2VPYA 1PT1A 2Q1AX 5CCXA 1SMYD 1PPYA 1YLEA 2JA5A 2WB1A 2B25A 4UC4A 4AYBA 2A6ED 3GTGA 5CD1A 2XDPA 3ML1A 4DMRA 1PYQA 2GAEA 2NAPA 3PLXB 3DMRA 2KI8A 2G6GA 4GA6A 4QIWA 3CQZA 1DMRA 1Y4ZA 1KQFA 5D6YA 5FTLA 2VPXA 1H5NA 2JIMA 1E32A 2VPZA 4AONB 1DMSA 1UHDA 1YNJD 4RV0A 1OGYA 1YNND 3ZGZA 4AZDA 1G8KA 1Y5IA 2JIPA 5ERGB 4AS1A 2JIRA 4C2MA 1CZ5A 2Q1CX 1CZ4A 1PQHA 1CR5A 1I50A 1E18A 1QCSA 5GLFA 5FTKA 3QQ7A 2R93A 3BQBA 3H0GA 2QQRA 1K83A 1Q16A 3ZJUA 1VC3B 2YVLA 3CZBA 3QWZA 5C18A 2E2HA 2VPWA 2C45A 3IR7A 4CQNA 5FTMA 2R92A 5EPPA 2PWYA 3FPRA 1AW8B 3IR6A 2PJHB 3HU1A 3GTPA 1H0HA 2LW6A 2V45A 1E61A 4AOKB 2QQSA 1PQFA 2E2IA 3ZJVA 2PI8A 3FKIA 5CCBA 1TWGA 4AAYA 2NVYA 2AE0X 5FTNA 5DYGA 4CRYG 1TMOA 2PJJA 4CRZA 3LGAA 2CW0D 2EEOB 4KLNA 2G5DA 2MM0A 2JV2A 2PICA 1I3QA 1ZC1A 1TWAA 1WCMA 2JIOA 2NYAA 2PMZA 5FTJA 3TIWA 3HU3A 2Q18X 2WAQA 2Y0SA 4KDLA 2A6HD 5C1BA 1TWCA 1I9GA 2O5JD 4AQ7A 1R27A 3QQ8A 3GTKA 5B6CA 4KDIA 1G8JA 3HKZA 2A68D 1S3SA 1SIWA 1FDOA 3GTLA 3GTOA 2Q19X 4KODA 1IW7D 3ZJTA 1UHEA 2V3VA 1R9TA 2R7ZA 3IR5A 1Y1VA 1QDNA 4NOHA 2GFAA 2YU9A 4ARIA 1E60A 2KY9A 5T5MD 2Q1DX 3CF2A 3GTJA 4D7ZB 2JA6A 4KO8A 2JIQA 5DYIA 2YUJA 2B63A 5D6XA 3GTMA 3O5AA 5D6WA 1PT0A 2BE5D 2VUMA 3TM7B 3OUGA 3HU2A 2GF7A 2MM2A 1E5VA 1TWHA 1AA6A 1Y1WA 3MB5A 5EQJB 1O54A 5T5ID 4ARCA 4CS0A 1FDIA 2A69D 1PYUB 1R7RA 1TWFA 3FPUA 1PQEA 1WLFA 1SFOA 4FIBA 2PNWA 1KQGA 4GA5A 3FPTA 2DMRA 1ZYRD 1EU1A 3LHDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVX A;  2E7Z A;  2IV2 X;  2JA7 A;  3GTQ A;  3QC8 A;  2VPY A;  1PT1 A;  1PPY A;  1YLE A;  2JA5 A;  2WB1 A;  4AYB A;  3GTG A;  3ML1 A;  4DMR A;  1PYQ A;  2NAP A;  3PLX B;  3DMR A;  2KI8 A;  4GA6 A;  4QIW A;  3CQZ A;  1DMR A;  1Y4Z A;  1KQF A;  5FTL A;  2VPX A;  1H5N A;  2JIM A;  1E32 A;  2VPZ A;  4AON B;  1DMS A;  1UHD A;  4RV0 A;  1OGY A;  4AZD A;  1G8K A;  1Y5I A;  2JIP A;  2JIR A;  4C2M A;  1CZ5 A;  1CZ4 A;  1PQH A;  1CR5 A;  1I50 A;  1E18 A;  1QCS A;  5GLF A;  5FTK A;  3QQ7 A;  2R93 A;  3H0G A;  1K83 A;  1Q16 A;  1VC3 B;  3QWZ A;  5C18 A;  2E2H A;  2VPW A;  2C45 A;  3IR7 A;  5FTM A;  2R92 A;  5EPP A;  1AW8 B;  3IR6 A;  2PJH B;  3HU1 A;  3GTP A;  1H0H A;  2V45 A;  1E61 A;  4AOK B;  1PQF A;  2E2I A;  3FKI A;  1TWG A;  4AAY A;  2NVY A;  5FTN A;  5DYG A;  4CRY G;  1TMO A;  4CRZ A;  2EEO B;  4KLN A;  2JV2 A;  1I3Q A;  1ZC1 A;  1TWA A;  1WCM A;  2JIO A;  2NYA A;  2PMZ A;  5FTJ A;  3TIW A;  3HU3 A;  2WAQ A;  2Y0S A;  4KDL A;  5C1B A;  1TWC A;  1R27 A;  3QQ8 A;  3GTK A;  5B6C A;  4KDI A;  1G8J A;  3HKZ A;  3GTO A;  1S3S A;  1SIW A;  1FDO A;  3GTL A;  4KOD A;  1IW7 D;  1UHE A;  2V3V A;  1R9T A;  2R7Z A;  3IR5 A;  1Y1V A;  1QDN A;  2YU9 A;  1E60 A;  5T5M D;  3CF2 A;  3GTJ A;  4D7Z B;  2JA6 A;  4KO8 A;  2JIQ A;  5DYI A;  2YUJ A;  2B63 A;  3GTM A;  3O5A A;  1PT0 A;  2VUM A;  3TM7 B;  3OUG A;  3HU2 A;  1E5V A;  1TWH A;  1AA6 A;  1Y1W A;  5T5I D;  4CS0 A;  1FDI A;  1PYU B;  1R7R A;  1TWF A;  1PQE A;  1WLF A;  1SFO A;  1KQG A;  4GA5 A;  2DMR A;  1EU1 A; 
#chains in the Genus database with same CATH topology
 2NVX A;  3SUK A;  2E7Z A;  2IV2 X;  2JA7 A;  3GTQ A;  3QC8 A;  2VPY A;  3X2J A;  1PT1 A;  2Q1A X;  3X2H A;  5CCX A;  1SMY D;  1PPY A;  1YLE A;  5GLY A;  2JA5 A;  2WB1 A;  2B25 A;  4UC4 A;  4AYB A;  2A6E D;  2ENG A;  3M3G A;  3SUM A;  3GTG A;  2XDP A;  5CD1 A;  3ML1 A;  4DMR A;  1PYQ A;  2GAE A;  2NAP A;  3ENG A;  3PLX B;  3DMR A;  2KI8 A;  2G6G A;  1HD5 A;  4GA6 A;  4L48 A;  4QIW A;  3CQZ A;  1DMR A;  1Y4Z A;  1KQF A;  5D6Y A;  1N10 A;  5FTL A;  2VPX A;  1H5N A;  2JIM A;  1E32 A;  2VPZ A;  4AON B;  1DMS A;  1UHD A;  1YNJ D;  4RV0 A;  1OGY A;  1YNN D;  3ZGZ A;  4AZD A;  1G8K A;  1Y5I A;  2JIP A;  5ERG B;  4AS1 A;  2JIR A;  4C2M A;  1CZ5 A;  2Q1C X;  1CZ4 A;  1PQH A;  1CR5 A;  1I50 A;  1E18 A;  4JJO A;  1QCS A;  5GLF A;  5FTK A;  3QQ7 A;  3X2I A;  2R93 A;  3BQB A;  3H0G A;  2QQR A;  1K83 A;  1Q16 A;  3X2K A;  4JS7 A;  3ZJU A;  1VC3 B;  4ENG A;  2YVL A;  3CZB A;  4FG4 A;  1WC2 A;  3QWZ A;  5C18 A;  2E2H A;  2VPW A;  2C45 A;  3IR7 A;  4CQN A;  5FTM A;  4ZM7 A;  2R92 A;  5EPP A;  2PWY A;  3FPR A;  1AW8 B;  3IR6 A;  2PJH B;  3HU1 A;  3GTP A;  1H0H A;  2LW6 A;  2V45 A;  5GM9 A;  1E61 A;  4AOK B;  2QQS A;  1PQF A;  2E2I A;  3ZJV A;  2PI8 A;  3FKI A;  5CCB A;  1TWG A;  1OA7 A;  2NVY A;  2AE0 X;  4AAY A;  5FTN A;  5DYG A;  4CRY G;  1TMO A;  2BH0 A;  2PJJ A;  4CRZ A;  3LGA A;  2CW0 D;  2EEO B;  4KLN A;  2G5D A;  2MM0 A;  2JV2 A;  2PIC A;  1I3Q A;  4FER A;  1ZC1 A;  4JCW A;  1TWA A;  1WCM A;  2JIO A;  2NYA A;  2PMZ A;  5FTJ A;  3TIW A;  3HU3 A;  2Q18 X;  2WAQ A;  2Y0S A;  3SUL A;  2KQA A;  4KDL A;  1OA9 A;  2A6H D;  5C1B A;  1TWC A;  1I9G A;  2O5J D;  4AQ7 A;  1BW3 A;  1R27 A;  3X2M A;  4FFT A;  3QQ8 A;  3GTK A;  3X2N A;  5B6C A;  4KDI A;  1G8J A;  3HKZ A;  2A68 D;  1S3S A;  2HCZ X;  1FDO A;  1SIW A;  3GTL A;  1L8F A;  4KOD A;  3GTO A;  2Q19 X;  1IW7 D;  3SUJ A;  3ZJT A;  4FG2 A;  1UHE A;  2V3V A;  1R9T A;  2R7Z A;  3IR5 A;  1Y1V A;  1QDN A;  4NOH A;  2GFA A;  3X2L A;  2YU9 A;  4ARI A;  1E60 A;  2KY9 A;  5T5M D;  2Q1D X;  3CF2 A;  3GTJ A;  4D7Z B;  2JA6 A;  4KO8 A;  2JIQ A;  5DYI A;  2YUJ A;  2B63 A;  5D6X A;  3GTM A;  3O5A A;  5D6W A;  1PT0 A;  2BE5 D;  2VUM A;  3TM7 B;  3OUG A;  3HU2 A;  4JP6 A;  2GF7 A;  2MM2 A;  1BW4 A;  1E5V A;  1TWH A;  1AA6 A;  1Y1W A;  3MB5 A;  5EQJ B;  1O54 A;  5T5I D;  5GLX A;  4ARC A;  4CS0 A;  1FDI A;  2A69 D;  1PYU B;  1R7R A;  1TWF A;  3D30 A;  3X2P A;  3FPU A;  1PQE A;  1WLF A;  1SFO A;  3X2G A;  4FIB A;  4AVR A;  2PNW A;  1KQG A;  5H4U A;  3X2O A;  4GA5 A;  3FPT A;  2DMR A;  4JP7 A;  1ZYR D;  1EU1 A;  3LHD A; 
#chains in the Genus database with same CATH homology
 2NVX A;  2E7Z A;  2IV2 X;  2JA7 A;  3GTQ A;  3QC8 A;  2VPY A;  1PT1 A;  2Q1A X;  5CCX A;  1SMY D;  1PPY A;  1YLE A;  2JA5 A;  2WB1 A;  2B25 A;  4UC4 A;  4AYB A;  2A6E D;  3GTG A;  5CD1 A;  2XDP A;  3ML1 A;  4DMR A;  1PYQ A;  2GAE A;  2NAP A;  3PLX B;  3DMR A;  2KI8 A;  2G6G A;  4GA6 A;  4QIW A;  3CQZ A;  1DMR A;  1Y4Z A;  1KQF A;  5D6Y A;  5FTL A;  2VPX A;  1H5N A;  2JIM A;  1E32 A;  2VPZ A;  4AON B;  1DMS A;  1UHD A;  1YNJ D;  4RV0 A;  1OGY A;  1YNN D;  3ZGZ A;  4AZD A;  1G8K A;  1Y5I A;  2JIP A;  5ERG B;  4AS1 A;  2JIR A;  4C2M A;  1CZ5 A;  2Q1C X;  1CZ4 A;  1PQH A;  1CR5 A;  1I50 A;  1E18 A;  1QCS A;  5GLF A;  5FTK A;  3QQ7 A;  2R93 A;  3BQB A;  3H0G A;  2QQR A;  1K83 A;  1Q16 A;  3ZJU A;  1VC3 B;  2YVL A;  3CZB A;  3QWZ A;  5C18 A;  2E2H A;  2VPW A;  2C45 A;  3IR7 A;  4CQN A;  5FTM A;  2R92 A;  5EPP A;  2PWY A;  3FPR A;  1AW8 B;  3IR6 A;  2PJH B;  3HU1 A;  3GTP A;  1H0H A;  2LW6 A;  2V45 A;  1E61 A;  4AOK B;  2QQS A;  1PQF A;  2E2I A;  3ZJV A;  2PI8 A;  3FKI A;  5CCB A;  1TWG A;  4AAY A;  2NVY A;  2AE0 X;  5FTN A;  5DYG A;  4CRY G;  1TMO A;  2PJJ A;  4CRZ A;  3LGA A;  2CW0 D;  2EEO B;  4KLN A;  2G5D A;  2MM0 A;  2JV2 A;  2PIC A;  1I3Q A;  1ZC1 A;  1TWA A;  1WCM A;  2JIO A;  2NYA A;  2PMZ A;  5FTJ A;  3TIW A;  3HU3 A;  2Q18 X;  2WAQ A;  2Y0S A;  4KDL A;  2A6H D;  5C1B A;  1TWC A;  1I9G A;  2O5J D;  4AQ7 A;  1R27 A;  3QQ8 A;  3GTK A;  5B6C A;  4KDI A;  1G8J A;  3HKZ A;  2A68 D;  1S3S A;  1SIW A;  1FDO A;  3GTL A;  3GTO A;  2Q19 X;  4KOD A;  1IW7 D;  3ZJT A;  1UHE A;  2V3V A;  1R9T A;  2R7Z A;  3IR5 A;  1Y1V A;  1QDN A;  4NOH A;  2GFA A;  2YU9 A;  4ARI A;  1E60 A;  2KY9 A;  5T5M D;  2Q1D X;  3CF2 A;  3GTJ A;  4D7Z B;  2JA6 A;  4KO8 A;  2JIQ A;  5DYI A;  2YUJ A;  2B63 A;  5D6X A;  3GTM A;  3O5A A;  5D6W A;  1PT0 A;  2BE5 D;  2VUM A;  3TM7 B;  3OUG A;  3HU2 A;  2GF7 A;  2MM2 A;  1E5V A;  1TWH A;  1AA6 A;  1Y1W A;  3MB5 A;  5EQJ B;  1O54 A;  5T5I D;  4ARC A;  4CS0 A;  1FDI A;  2A69 D;  1PYU B;  1R7R A;  1TWF A;  3FPU A;  1PQE A;  1WLF A;  1SFO A;  4FIB A;  2PNW A;  1KQG A;  4GA5 A;  3FPT A;  2DMR A;  1ZYR D;  1EU1 A;  3LHD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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