1D6RI

Crystal structure of cancer chemopreventive bowman-birk inhibitor in ternary complex with bovine trypsin at 2.3 a resolution. structural basis of janus-faced serine protease inhibitor specificity
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
58
structure length
58
Chain Sequence
KPCCDQCACTKSNPPQCRCSDMRLNSCHSACKSCICALSYPAQCFCVDITDFCYEPCK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords TRYPSINOGEN
publication title Crystal structure of cancer chemopreventive Bowman-Birk inhibitor in ternary complex with bovine trypsin at 2.3 A resolution. Structural basis of Janus-faced serine protease inhibitor specificity.
pubmed doi rcsb
total genus 8
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 1999-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00228 Bowman-Birk_leg Bowman-Birk serine protease inhibitor family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.69.10 Mainly Beta Ribbon Cysteine Protease (Bromelain) Inhibitor, subunit H Cysteine Protease (Bromelain) Inhibitor, subunit H 1d6rI00
2G81I 1C2AA 1K9BA 2BI6H 1BBIA 2R33A 1D6RI 2FJ8A 2AIHA 5J4SB 1TX6I 3MYWI 2BBIA 1PBIA 1MVZA 1H34A 3RU4B 5J4QB 2QN5B 2ILNI 1PI2A 1BI6H
chains in the Genus database with same CATH superfamily
2G81I 1C2AA 1K9BA 2BI6H 1BBIA 2R33A 1D6RI 2FJ8A 2AIHA 5J4SB 1TX6I 3MYWI 2BBIA 1PBIA 1MVZA 1H34A 3RU4B 5J4QB 2QN5B 2ILNI 1PI2A 1BI6H
chains in the Genus database with same CATH topology
2G81I 1C2AA 1K9BA 2BI6H 1BBIA 2R33A 1D6RI 2FJ8A 2AIHA 5J4SB 1TX6I 3MYWI 2BBIA 1PBIA 1MVZA 1H34A 3RU4B 5J4QB 2QN5B 2ILNI 1PI2A 1BI6H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2G81 I;  1C2A A;  1K9B A;  2BI6 H;  1BBI A;  2R33 A;  1D6R I;  2FJ8 A;  2AIH A;  5J4S B;  1TX6 I;  3MYW I;  2BBI A;  1PBI A;  1MVZ A;  1H34 A;  3RU4 B;  5J4Q B;  2QN5 B;  2ILN I;  1PI2 A;  1BI6 H; 
#chains in the Genus database with same CATH topology
 2G81 I;  1C2A A;  1K9B A;  2BI6 H;  1BBI A;  2R33 A;  1D6R I;  2FJ8 A;  2AIH A;  5J4S B;  1TX6 I;  3MYW I;  2BBI A;  1PBI A;  1MVZ A;  1H34 A;  3RU4 B;  5J4Q B;  2QN5 B;  2ILN I;  1PI2 A;  1BI6 H; 
#chains in the Genus database with same CATH homology
 2G81 I;  1C2A A;  1K9B A;  2BI6 H;  1BBI A;  2R33 A;  1D6R I;  2FJ8 A;  2AIH A;  5J4S B;  1TX6 I;  3MYW I;  2BBI A;  1PBI A;  1MVZ A;  1H34 A;  3RU4 B;  5J4Q B;  2QN5 B;  2ILN I;  1PI2 A;  1BI6 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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