1DIQA

Crystal structure of p-cresol methylhydroxylase with substrate bound
Total Genus 182
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
182
sequence length
515
structure length
515
Chain Sequence
AVLPKGVTQGEFNKAVQKFRALLGDDNVLVESDQLVPYNKIMMPVENAAHAPSAAVTATTVEQVQGVVKICNEHKIPIWTISTGRNFGYGSAAPVQRGQVILDLKKMNKIIKIDPEMCYALVEPGVTFGQMYDYIQENNLPVMLSFSAPSAIAGPVGNTMDRGVGYTPYGEHFMMQCGMEVVLANGDVYRTGMGGVPGSNTWQIFKWGYGPTLDGMFTQANYGICTKMGFWLMPKPPVFKPFEVIFEDEADIVEIVDALRPLRMSNTIPNSVVIASTLWEAGSAHLTRAQYTTEPGHTPDSVIKQMQKDTGMGAWNLYAALYGTQEQVDVNWKIVTDVFKKLGKGRIVTQEEAGDTQPFKYRAQLMSGVPNLQEFGLYNWRGGGGSMWFAPVSEARGSECKKQAAMAKRVLHKYGLDYVAEFIVAPRDMHHVIDVLYDRTNPEETKRADACFNELLDEFEKEGYAVYRVNTRFQDRVAQSYGPVKRKLEHAIKRAVDPNNILAPGRSGIDLNNDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structures of the flavocytochrome p-cresol methylhydroxylase and its enzyme-substrate complex: gated substrate entry and proton relays support the proposed catalytic mechanism.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords P-CRESOL METHYLHYDROXYLASE
total genus 182
structure length 515
sequence length 515
chains with identical sequence B
ec nomenclature ec 1.17.9.1: 4-methylphenol dehydrogenase (hydroxylating).
pdb deposition date 1999-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1diqA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1diqA02
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1diqA03
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1diqA01
2O3GA 5AE2A 3NVZB 3W8ZA 1UXYA 1N5XA 4BC7A 3PM9A 1W1MA 2VFTA 3AN1A 2E3TA 4HG0A 4EC3A 5D79A 2Q85A 2PLSA 3S1EA 3LLBA 1SB3B 1E8HA 5G5HB 3VTEA 1N63C 4BBYA 1VAOA 3KJMA 2W54A 4PWBA 3S1DA 3NVWB 2Q4WA 4BCAA 3BW7A 3D2JA 1MBTA 3W8WA 1F0XA 4MLAA 2P4PA 3TSJA 4PZFA 1FO4A 4ZOHB 1AHVA 1ZR6A 4JAYA 1FFVC 2QPMA 3DQ0A 3AM9A 3HRDC 1QLTA 2BVFA 2VFVA 3EUB3 3FWAA 1W1QA 4PVEA 1W1SA 3B9JB 1DIQA 2P13A 2VFRA 2MBRA 2VFSA 1JROA 4PWCA 1WVEA 5HQXA 3FW8A 2YVSA 4PVJA 1VDVA 4PYTA 1AHUA 1W1JA 5FXDA 5AE3A 1MBBA 4O95A 4BC9A 3S1FA 2RK5A 2R2ZA 5HHZA 2I0KA 3DEDA 3LAEA 2VFUA 1E8GA 1W1LA 1JRPA 4DNSA 1RM6B 2GQTA 2P3HA 2QKNA 1HSKA 5FXFA 1I19A 2NQWA 2VAOA 1N62C 3S1CA 3TSHA 1N60C 3NRZB 1FFUC 3D2HA 3SR6B 1N61C 4PVHA 4JB1A 3GSYA 3W8XA 3ETRB 2R8DA 4XLOA 3FW9A 1AHZA 3NS1B 2W55A 3FW7A 1WYGA 5ADZA 3D2DA 1W1RA 2GQUA 3C0PA 1W1OA 2BVGA 5FXPA 2BVHA 1N5WC 1DZNA 3NVYB 1DIIA 2EXRA 1E0YA 2W3RA 3TX1A 2AXRA 1ZXIC 3AMZA 1FIQB 2OAIA 4UD8A 3I99A 1W1KA 5AE1A 3NVVB 5FXEA 5G5GB 4PVKA 1QLUA 1V97A 1E8FA 2PLIA 2W3SA 5HMRA 1WVFA 4OALA 4ML8A 3JS8A 1T3QC
chains in the Genus database with same CATH superfamily
2O3GA 5AE2A 3NVZB 5AWVA 3W8ZA 1UXYA 1N5XA 4BC7A 2Y4GA 3PM9A 1W1MA 2VFTA 3AN1A 2E3TA 2Y3SA 4EC3A 4HG0A 5D79A 2Q85A 2PLSA 3S1EA 3POPA 3LLBA 1SB3B 1E8HA 5G5HB 3VTEA 1N63C 5I1WA 4BBYA 1VAOA 3KJMA 2W54A 4PWBA 3S1DA 3NVWB 2Q4WA 4BCAA 3BW7A 3D2JA 1MBTA 3W8WA 1F0XA 4MLAA 2P4PA 3TSJA 4PZFA 1FO4A 4ZOHB 1AHVA 1ZR6A 4JAYA 1FFVC 2QPMA 3DQ0A 3AM9A 3HRDC 1QLTA 2BVFA 2VFVA 3EUB3 5I1VA 3FWAA 1W1QA 4PVEA 1W1SA 3B9JB 1DIQA 2P13A 2VFRA 2MBRA 2VFSA 1JROA 4PWCA 1WVEA 5HQXA 3FW8A 2YVSA 4PVJA 1VDVA 4PYTA 1AHUA 1W1JA 5FXDA 5AE3A 1MBBA 4O95A 4BC9A 3S1FA 2RK5A 2R2ZA 5HHZA 2I0KA 3DEDA 3LAEA 2VFUA 1E8GA 1W1LA 3HSUA 1JRPA 4DNSA 1RM6B 2GQTA 2P3HA 2UUUA 2QKNA 1HSKA 3EJEB 5FXFA 1I19A 2NQWA 2VAOA 1N62C 3PQBA 3S1CA 3TSHA 2IPIA 1N60C 3NRZB 1FFUC 3D2HA 2UUVA 3SR6B 1N61C 4PVHA 4JB1A 3GSYA 3W8XA 2Y08A 3ETRB 5L6GA 2R8DA 4XLOA 3RJAA 3FW9A 1AHZA 3NS1B 2W55A 3FW7A 1WYGA 5ADZA 3D2DA 1W1RA 2GQUA 3C0PA 1W1OA 2BVGA 5FXPA 2BVHA 1N5WC 1DZNA 3NVYB 3RJ8A 1DIIA 2EXRA 1E0YA 2W3RA 3TX1A 2AXRA 1ZXIC 3AMZA 1FIQB 2OAIA 4UD8A 3I99A 5L6FA 1W1KA 5AE1A 3NVVB 5FXEA 2Y3RA 5G5GB 4PVKA 1QLUA 1V97A 1E8FA 2PLIA 2W3SA 3EJBB 5K8EA 2WDWA 5HMRA 1WVFA 4OALA 4ML8A 3JS8A 3EJDB 1T3QC
chains in the Genus database with same CATH topology
2O3GA 5AE2A 3NVZB 5AWVA 3W8ZA 1UXYA 1N5XA 4BC7A 2Y4GA 3PM9A 1W1MA 2VFTA 3AN1A 2E3TA 2Y3SA 4EC3A 4HG0A 5D79A 2Q85A 2PLSA 3S1EA 3POPA 3LLBA 1SB3B 1E8HA 5G5HB 3VTEA 1N63C 5I1WA 4BBYA 1VAOA 3KJMA 2W54A 4PWBA 3S1DA 3NVWB 2Q4WA 4BCAA 3BW7A 3D2JA 1MBTA 3W8WA 1F0XA 4MLAA 2P4PA 3TSJA 4PZFA 1FO4A 4ZOHB 1AHVA 1ZR6A 4JAYA 1FFVC 2QPMA 3DQ0A 3AM9A 3HRDC 1QLTA 2BVFA 2VFVA 3EUB3 5I1VA 3FWAA 1W1QA 4PVEA 1W1SA 3B9JB 1DIQA 2P13A 2VFRA 2MBRA 2VFSA 1JROA 4PWCA 1WVEA 5HQXA 3FW8A 2YVSA 4PVJA 1VDVA 4PYTA 1AHUA 1W1JA 5FXDA 5AE3A 1MBBA 4O95A 4BC9A 3S1FA 2RK5A 2R2ZA 5HHZA 2I0KA 3DEDA 3LAEA 2VFUA 1E8GA 1W1LA 3HSUA 1JRPA 4DNSA 1RM6B 2GQTA 2P3HA 2UUUA 2QKNA 1HSKA 5FXFA 1I19A 2NQWA 2VAOA 1N62C 3PQBA 3S1CA 3TSHA 2IPIA 1N60C 3NRZB 1FFUC 3D2HA 2UUVA 3SR6B 1N61C 4PVHA 4JB1A 3GSYA 3W8XA 2Y08A 3ETRB 5L6GA 2R8DA 4XLOA 3RJAA 3FW9A 1AHZA 3NS1B 2W55A 3FW7A 1WYGA 5ADZA 3D2DA 1W1RA 2GQUA 3C0PA 1W1OA 2BVGA 5FXPA 2BVHA 1N5WC 1DZNA 3NVYB 3RJ8A 1DIIA 2EXRA 1E0YA 2W3RA 3TX1A 2AXRA 1ZXIC 3AMZA 1FIQB 2OAIA 4UD8A 3I99A 5L6FA 1W1KA 5AE1A 3NVVB 5FXEA 2Y3RA 5G5GB 4PVKA 1QLUA 1V97A 1E8FA 2PLIA 2W3SA 5K8EA 2WDWA 5HMRA 1WVFA 4OALA 4ML8A 3JS8A 1T3QC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O3G A;  5AE2 A;  3NVZ B;  3W8Z A;  1UXY A;  1N5X A;  4BC7 A;  3PM9 A;  1W1M A;  2VFT A;  3AN1 A;  2E3T A;  4HG0 A;  4EC3 A;  5D79 A;  2Q85 A;  2PLS A;  3S1E A;  3LLB A;  1SB3 B;  1E8H A;  5G5H B;  3VTE A;  1N63 C;  4BBY A;  1VAO A;  3KJM A;  2W54 A;  4PWB A;  3S1D A;  3NVW B;  2Q4W A;  4BCA A;  3BW7 A;  3D2J A;  1MBT A;  3W8W A;  1F0X A;  4MLA A;  2P4P A;  3TSJ A;  4PZF A;  1FO4 A;  4ZOH B;  1AHV A;  1ZR6 A;  4JAY A;  1FFV C;  2QPM A;  3DQ0 A;  3AM9 A;  3HRD C;  1QLT A;  2BVF A;  2VFV A;  3EUB 3;  3FWA A;  1W1Q A;  4PVE A;  1W1S A;  3B9J B;  1DIQ A;  2P13 A;  2VFR A;  2MBR A;  2VFS A;  1JRO A;  4PWC A;  1WVE A;  5HQX A;  3FW8 A;  2YVS A;  4PVJ A;  1VDV A;  4PYT A;  1AHU A;  1W1J A;  5FXD A;  5AE3 A;  1MBB A;  4O95 A;  4BC9 A;  3S1F A;  2RK5 A;  2R2Z A;  5HHZ A;  2I0K A;  3DED A;  3LAE A;  2VFU A;  1E8G A;  1W1L A;  1JRP A;  4DNS A;  1RM6 B;  2GQT A;  2P3H A;  2QKN A;  1HSK A;  5FXF A;  1I19 A;  2NQW A;  2VAO A;  1N62 C;  3S1C A;  3TSH A;  1N60 C;  3NRZ B;  1FFU C;  3D2H A;  3SR6 B;  1N61 C;  4PVH A;  4JB1 A;  3GSY A;  3W8X A;  3ETR B;  2R8D A;  4XLO A;  3FW9 A;  1AHZ A;  3NS1 B;  2W55 A;  3FW7 A;  1WYG A;  5ADZ A;  3D2D A;  1W1R A;  2GQU A;  3C0P A;  1W1O A;  2BVG A;  5FXP A;  2BVH A;  1N5W C;  1DZN A;  3NVY B;  1DII A;  2EXR A;  1E0Y A;  2W3R A;  3TX1 A;  2AXR A;  1ZXI C;  3AMZ A;  1FIQ B;  2OAI A;  4UD8 A;  3I99 A;  1W1K A;  5AE1 A;  3NVV B;  5FXE A;  5G5G B;  4PVK A;  1QLU A;  1V97 A;  1E8F A;  2PLI A;  2W3S A;  5HMR A;  1WVF A;  4OAL A;  4ML8 A;  3JS8 A;  1T3Q C; 
#chains in the Genus database with same CATH topology
 2O3G A;  5AE2 A;  3NVZ B;  5AWV A;  3W8Z A;  1UXY A;  1N5X A;  4BC7 A;  2Y4G A;  3PM9 A;  1W1M A;  2VFT A;  3AN1 A;  2E3T A;  2Y3S A;  4EC3 A;  4HG0 A;  5D79 A;  2Q85 A;  2PLS A;  3S1E A;  3POP A;  3LLB A;  1SB3 B;  1E8H A;  5G5H B;  3VTE A;  1N63 C;  5I1W A;  4BBY A;  1VAO A;  3KJM A;  2W54 A;  4PWB A;  3S1D A;  3NVW B;  2Q4W A;  4BCA A;  3BW7 A;  3D2J A;  1MBT A;  3W8W A;  1F0X A;  4MLA A;  2P4P A;  3TSJ A;  4PZF A;  1FO4 A;  4ZOH B;  1AHV A;  1ZR6 A;  4JAY A;  1FFV C;  2QPM A;  3DQ0 A;  3AM9 A;  3HRD C;  1QLT A;  2BVF A;  2VFV A;  3EUB 3;  5I1V A;  3FWA A;  1W1Q A;  4PVE A;  1W1S A;  3B9J B;  1DIQ A;  2P13 A;  2VFR A;  2MBR A;  2VFS A;  1JRO A;  4PWC A;  1WVE A;  5HQX A;  3FW8 A;  2YVS A;  4PVJ A;  1VDV A;  4PYT A;  1AHU A;  1W1J A;  5FXD A;  5AE3 A;  1MBB A;  4O95 A;  4BC9 A;  3S1F A;  2RK5 A;  2R2Z A;  5HHZ A;  2I0K A;  3DED A;  3LAE A;  2VFU A;  1E8G A;  1W1L A;  3HSU A;  1JRP A;  4DNS A;  1RM6 B;  2GQT A;  2P3H A;  2UUU A;  2QKN A;  1HSK A;  3EJE B;  5FXF A;  1I19 A;  2NQW A;  2VAO A;  1N62 C;  3PQB A;  3S1C A;  3TSH A;  2IPI A;  1N60 C;  3NRZ B;  1FFU C;  3D2H A;  2UUV A;  3SR6 B;  1N61 C;  4PVH A;  4JB1 A;  3GSY A;  3W8X A;  2Y08 A;  3ETR B;  5L6G A;  2R8D A;  4XLO A;  3RJA A;  3FW9 A;  1AHZ A;  3NS1 B;  2W55 A;  3FW7 A;  1WYG A;  5ADZ A;  3D2D A;  1W1R A;  2GQU A;  3C0P A;  1W1O A;  2BVG A;  5FXP A;  2BVH A;  1N5W C;  1DZN A;  3NVY B;  3RJ8 A;  1DII A;  2EXR A;  1E0Y A;  2W3R A;  3TX1 A;  2AXR A;  1ZXI C;  3AMZ A;  1FIQ B;  2OAI A;  4UD8 A;  3I99 A;  5L6F A;  1W1K A;  5AE1 A;  3NVV B;  5FXE A;  2Y3R A;  5G5G B;  4PVK A;  1QLU A;  1V97 A;  1E8F A;  2PLI A;  2W3S A;  3EJB B;  5K8E A;  2WDW A;  5HMR A;  1WVF A;  4OAL A;  4ML8 A;  3JS8 A;  3EJD B;  1T3Q C; 
#chains in the Genus database with same CATH homology
 2O3G A;  5AE2 A;  3NVZ B;  5AWV A;  3W8Z A;  1UXY A;  1N5X A;  4BC7 A;  2Y4G A;  3PM9 A;  1W1M A;  2VFT A;  3AN1 A;  2E3T A;  2Y3S A;  4EC3 A;  4HG0 A;  5D79 A;  2Q85 A;  2PLS A;  3S1E A;  3POP A;  3LLB A;  1SB3 B;  1E8H A;  5G5H B;  3VTE A;  1N63 C;  5I1W A;  4BBY A;  1VAO A;  3KJM A;  2W54 A;  4PWB A;  3S1D A;  3NVW B;  2Q4W A;  4BCA A;  3BW7 A;  3D2J A;  1MBT A;  3W8W A;  1F0X A;  4MLA A;  2P4P A;  3TSJ A;  4PZF A;  1FO4 A;  4ZOH B;  1AHV A;  1ZR6 A;  4JAY A;  1FFV C;  2QPM A;  3DQ0 A;  3AM9 A;  3HRD C;  1QLT A;  2BVF A;  2VFV A;  3EUB 3;  5I1V A;  3FWA A;  1W1Q A;  4PVE A;  1W1S A;  3B9J B;  1DIQ A;  2P13 A;  2VFR A;  2MBR A;  2VFS A;  1JRO A;  4PWC A;  1WVE A;  5HQX A;  3FW8 A;  2YVS A;  4PVJ A;  1VDV A;  4PYT A;  1AHU A;  1W1J A;  5FXD A;  5AE3 A;  1MBB A;  4O95 A;  4BC9 A;  3S1F A;  2RK5 A;  2R2Z A;  5HHZ A;  2I0K A;  3DED A;  3LAE A;  2VFU A;  1E8G A;  1W1L A;  3HSU A;  1JRP A;  4DNS A;  1RM6 B;  2GQT A;  2P3H A;  2UUU A;  2QKN A;  1HSK A;  5FXF A;  1I19 A;  2NQW A;  2VAO A;  1N62 C;  3PQB A;  3S1C A;  3TSH A;  2IPI A;  1N60 C;  3NRZ B;  1FFU C;  3D2H A;  2UUV A;  3SR6 B;  1N61 C;  4PVH A;  4JB1 A;  3GSY A;  3W8X A;  2Y08 A;  3ETR B;  5L6G A;  2R8D A;  4XLO A;  3RJA A;  3FW9 A;  1AHZ A;  3NS1 B;  2W55 A;  3FW7 A;  1WYG A;  5ADZ A;  3D2D A;  1W1R A;  2GQU A;  3C0P A;  1W1O A;  2BVG A;  5FXP A;  2BVH A;  1N5W C;  1DZN A;  3NVY B;  3RJ8 A;  1DII A;  2EXR A;  1E0Y A;  2W3R A;  3TX1 A;  2AXR A;  1ZXI C;  3AMZ A;  1FIQ B;  2OAI A;  4UD8 A;  3I99 A;  5L6F A;  1W1K A;  5AE1 A;  3NVV B;  5FXE A;  2Y3R A;  5G5G B;  4PVK A;  1QLU A;  1V97 A;  1E8F A;  2PLI A;  2W3S A;  5K8E A;  2WDW A;  5HMR A;  1WVF A;  4OAL A;  4ML8 A;  3JS8 A;  1T3Q C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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