The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
161
|
sequence length |
557
|
structure length |
513
|
Chain Sequence |
EIETFYKMLTQRAEIDRAFEEAAGSAETLSVERLVTFLQHQQREEEAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQDMDQPLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCSLEQQRVMARHLRAILGPILLDQPLDGVTTSLPSPEQLKGKILLKGKKLKLVPELSDMIIYCKSVHFGGFSSPGTSGQAFYEMASFSESRALRLLQESGNGFVRHNVSCLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGGCGYVLKPAFLRDPNTTFNSRALTQGPWWRPERLRVRIISGQQLPKVNKNKNSIVDPKVIVEIHGVGRDTGSRQTAVITNNGFNPRWDMEFEFEVTVPDLALVRFMVEDYDSSSKNDFIGQSTIPWNSLKQGYRHVHLLSKNGDQHPSATLFVKISIQD
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
pubmed doi rcsb |
| source organism |
Rattus norvegicus
|
| molecule tags |
Lipid degradation
|
| molecule keywords |
PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C, ISOZYME DELTA1
|
| total genus |
161
|
| structure length |
513
|
| sequence length |
557
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
3.1.4.11: Phosphoinositide phospholipase C. |
| pdb deposition date | 1996-08-24 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00168 | C2 | C2 domain |
| A | PF00387 | PI-PLC-Y | Phosphatidylinositol-specific phospholipase C, Y domain |
| A | PF00388 | PI-PLC-X | Phosphatidylinositol-specific phospholipase C, X domain |
| A | PF09279 | EF-hand_like | Phosphoinositide-specific phospholipase C, efhand-like |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Recoverin; domain 1 | EF-hand | ||
| Mainly Beta | Sandwich | Immunoglobulin-like | C2 domain | ||
| Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Phosphatidylinositol (PI) phosphodiesterase |
