1E41A

Death domain from human fadd/mort1
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
104
structure length
104
Chain Sequence
GSHMGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Apoptosis
molecule keywords FADD PROTEIN
publication title The Three-Dimensional Solution Structure and Dynamic Properties of the Human Fadd Death Domain
pubmed doi rcsb
source organism Homo sapiens
total genus 29
structure length 104
sequence length 104
ec nomenclature
pdb deposition date 2000-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 1e41A00
4RHWA 4M9SA 2MS8A 2NZ7A 3MOPK 2A5YB 1E41A 1NGRA 2BBZA 2N83A 2OF5H 4QOBA 3J6JA 3LQRA 2GF5A 4FH0A 2L6AA 1ICHA 2NAQA 3LQQA 1PN5A 2D96A 2BBRA 2N80A 2O71A 1WMGA 3YGSC 4A2QA 2LWEA 2MB9A 2DBGA 1CWWA 4O6XA 4P4HA 2M5VA 3J63A 2B1WA 2LWDA 3MOPG 1E3YA 4I16A 1CY5A 1N3KA 4ZBWA 1A1WA 2DBFA 2LS7A 4DWNA 2MS7A 3CRDA 4D8OA 1C15A 4EWIA 2N97A 2MPCA 4IZ7B 4JUPA 3QF2A 1YGOA 4F44A 2IB1A 2P1HA 2N1FA 1WH4A 3EZQB 2DO9A 1D2ZA 4IZ5E 1A1ZA 4RHWE 2HM2Q 4E9MA 1DGNA 2N00A 4M9XA 2YVIA 2YGSA 4A2WA 2L9MA 4LWDA 2F1SA 2MN4A 2NSNA 3KATA 4P4HI 1DDFA 2YQFA 2DBDA 2YU0A 4N1LA 2G7RA 4JQWA 4NQKA 4O9LA 3CL3A 2A9IA 4O9FA 4UZ0A 3MOPA 4N1JA 1FADA 2N7ZA 2KN6A 4F42A 4O7QA 4IZAB 4M9ZA 1UCPA 2KM6A 2OF5A 4N1KA 3T6PA 1WXPA 2VGQA 3EZQA 2DBHA 1Z6TA 3YGSP 1D2ZB
chains in the Genus database with same CATH superfamily
4RHWA 4M9SA 2MS8A 2NZ7A 3MOPK 2A5YB 1E41A 1NGRA 2BBZA 2N83A 2OF5H 4QOBA 2XV9A 3J6JA 3LQRA 2GF5A 4FH0A 2L6AA 1ICHA 2NAQA 3LQQA 1PN5A 2D96A 2BBRA 2N80A 2O71A 1WMGA 3YGSC 4A2QA 2LWEA 2MB9A 2DBGA 1CWWA 4O6XA 4P4HA 2M5VA 3J63A 2B1WA 2LWDA 3MOPG 1E3YA 4I16A 1CY5A 1N3KA 4ZBWA 1A1WA 2DBFA 2LS7A 4DWNA 2MS7A 3CRDA 4D8OA 1C15A 4EWIA 2N97A 2MPCA 4IZ7B 4JUPA 3QF2A 1YGOA 4F44A 2IB1A 2P1HA 2N1FA 1WH4A 3EZQB 2DO9A 1D2ZA 4IZ5E 1A1ZA 4RHWE 2HM2Q 4E9MA 1DGNA 2N00A 4M9XA 2YVIA 2YGSA 4A2WA 2L9MA 4LWDA 2F1SA 2MN4A 2NSNA 3KATA 4P4HI 1DDFA 2MJMA 2YQFA 2DBDA 2YU0A 4N1LA 2G7RA 4JQWA 4NQKA 4O9LA 3CL3A 2A9IA 4O9FA 4UZ0A 3MOPA 4N1JA 1FADA 2N7ZA 2KN6A 4F42A 4O7QA 4IZAB 4M9ZA 1UCPA 2KM6A 2OF5A 4N1KA 3T6PA 1WXPA 2VGQA 3EZQA 2DBHA 1Z6TA 3YGSP 1D2ZB
chains in the Genus database with same CATH topology
4RHWA 4M9SA 2MS8A 2NZ7A 3MOPK 2A5YB 1E41A 1NGRA 2BBZA 2N83A 2OF5H 4QOBA 2XV9A 3J6JA 3LQRA 2GF5A 4FH0A 2L6AA 1ICHA 2NAQA 3LQQA 1PN5A 2D96A 2BBRA 2N80A 2O71A 1WMGA 3YGSC 4A2QA 2LWEA 2MB9A 2DBGA 1CWWA 4O6XA 4P4HA 2M5VA 3J63A 2B1WA 2LWDA 3MOPG 1E3YA 4I16A 1CY5A 1N3KA 4ZBWA 1A1WA 2DBFA 2LS7A 4DWNA 2MS7A 3CRDA 4D8OA 1C15A 4EWIA 2N97A 2MPCA 4IZ7B 4JUPA 3QF2A 1YGOA 4F44A 2IB1A 2P1HA 2N1FA 1WH4A 3EZQB 2DO9A 1D2ZA 4IZ5E 1A1ZA 4RHWE 2HM2Q 4E9MA 1DGNA 2N00A 4M9XA 2YVIA 2YGSA 4A2WA 2L9MA 4LWDA 2F1SA 2MN4A 2NSNA 3KATA 4P4HI 1DDFA 2MJMA 2YQFA 2DBDA 2YU0A 4N1LA 2G7RA 4JQWA 4NQKA 4O9LA 3CL3A 2A9IA 4O9FA 4UZ0A 3MOPA 4N1JA 1FADA 2N7ZA 2KN6A 4F42A 4O7QA 4IZAB 4M9ZA 1UCPA 2KM6A 2OF5A 4N1KA 3T6PA 1WXPA 2VGQA 3EZQA 2DBHA 1Z6TA 3YGSP 1D2ZB
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4RHW A;  4M9S A;  2MS8 A;  2NZ7 A;  3MOP K;  2A5Y B;  1E41 A;  1NGR A;  2BBZ A;  2N83 A;  2OF5 H;  4QOB A;  3J6J A;  3LQR A;  2GF5 A;  4FH0 A;  2L6A A;  1ICH A;  2NAQ A;  3LQQ A;  1PN5 A;  2D96 A;  2BBR A;  2N80 A;  2O71 A;  1WMG A;  3YGS C;  4A2Q A;  2LWE A;  2MB9 A;  2DBG A;  1CWW A;  4O6X A;  4P4H A;  2M5V A;  3J63 A;  2B1W A;  2LWD A;  3MOP G;  1E3Y A;  4I16 A;  1CY5 A;  1N3K A;  4ZBW A;  1A1W A;  2DBF A;  2LS7 A;  4DWN A;  2MS7 A;  3CRD A;  4D8O A;  1C15 A;  4EWI A;  2N97 A;  2MPC A;  4IZ7 B;  4JUP A;  3QF2 A;  1YGO A;  4F44 A;  2IB1 A;  2P1H A;  2N1F A;  1WH4 A;  3EZQ B;  2DO9 A;  1D2Z A;  4IZ5 E;  1A1Z A;  4RHW E;  2HM2 Q;  4E9M A;  1DGN A;  2N00 A;  4M9X A;  2YVI A;  2YGS A;  4A2W A;  2L9M A;  4LWD A;  2F1S A;  2MN4 A;  2NSN A;  3KAT A;  4P4H I;  1DDF A;  2YQF A;  2DBD A;  2YU0 A;  4N1L A;  2G7R A;  4JQW A;  4NQK A;  4O9L A;  3CL3 A;  2A9I A;  4O9F A;  4UZ0 A;  3MOP A;  4N1J A;  1FAD A;  2N7Z A;  2KN6 A;  4F42 A;  4O7Q A;  4IZA B;  4M9Z A;  1UCP A;  2KM6 A;  2OF5 A;  4N1K A;  3T6P A;  1WXP A;  2VGQ A;  3EZQ A;  2DBH A;  1Z6T A;  3YGS P;  1D2Z B; 
#chains in the Genus database with same CATH topology
 4RHW A;  4M9S A;  2MS8 A;  2NZ7 A;  3MOP K;  2A5Y B;  1E41 A;  1NGR A;  2BBZ A;  2N83 A;  2OF5 H;  4QOB A;  2XV9 A;  3J6J A;  3LQR A;  2GF5 A;  4FH0 A;  2L6A A;  1ICH A;  2NAQ A;  3LQQ A;  1PN5 A;  2D96 A;  2BBR A;  2N80 A;  2O71 A;  1WMG A;  3YGS C;  4A2Q A;  2LWE A;  2MB9 A;  2DBG A;  1CWW A;  4O6X A;  4P4H A;  2M5V A;  3J63 A;  2B1W A;  2LWD A;  3MOP G;  1E3Y A;  4I16 A;  1CY5 A;  1N3K A;  4ZBW A;  1A1W A;  2DBF A;  2LS7 A;  4DWN A;  2MS7 A;  3CRD A;  4D8O A;  1C15 A;  4EWI A;  2N97 A;  2MPC A;  4IZ7 B;  4JUP A;  3QF2 A;  1YGO A;  4F44 A;  2IB1 A;  2P1H A;  2N1F A;  1WH4 A;  3EZQ B;  2DO9 A;  1D2Z A;  4IZ5 E;  1A1Z A;  4RHW E;  2HM2 Q;  4E9M A;  1DGN A;  2N00 A;  4M9X A;  2YVI A;  2YGS A;  4A2W A;  2L9M A;  4LWD A;  2F1S A;  2MN4 A;  2NSN A;  3KAT A;  4P4H I;  1DDF A;  2MJM A;  2YQF A;  2DBD A;  2YU0 A;  4N1L A;  2G7R A;  4JQW A;  4NQK A;  4O9L A;  3CL3 A;  2A9I A;  4O9F A;  4UZ0 A;  3MOP A;  4N1J A;  1FAD A;  2N7Z A;  2KN6 A;  4F42 A;  4O7Q A;  4IZA B;  4M9Z A;  1UCP A;  2KM6 A;  2OF5 A;  4N1K A;  3T6P A;  1WXP A;  2VGQ A;  3EZQ A;  2DBH A;  1Z6T A;  3YGS P;  1D2Z B; 
#chains in the Genus database with same CATH homology
 4RHW A;  4M9S A;  2MS8 A;  2NZ7 A;  3MOP K;  2A5Y B;  1E41 A;  1NGR A;  2BBZ A;  2N83 A;  2OF5 H;  4QOB A;  2XV9 A;  3J6J A;  3LQR A;  2GF5 A;  4FH0 A;  2L6A A;  1ICH A;  2NAQ A;  3LQQ A;  1PN5 A;  2D96 A;  2BBR A;  2N80 A;  2O71 A;  1WMG A;  3YGS C;  4A2Q A;  2LWE A;  2MB9 A;  2DBG A;  1CWW A;  4O6X A;  4P4H A;  2M5V A;  3J63 A;  2B1W A;  2LWD A;  3MOP G;  1E3Y A;  4I16 A;  1CY5 A;  1N3K A;  4ZBW A;  1A1W A;  2DBF A;  2LS7 A;  4DWN A;  2MS7 A;  3CRD A;  4D8O A;  1C15 A;  4EWI A;  2N97 A;  2MPC A;  4IZ7 B;  4JUP A;  3QF2 A;  1YGO A;  4F44 A;  2IB1 A;  2P1H A;  2N1F A;  1WH4 A;  3EZQ B;  2DO9 A;  1D2Z A;  4IZ5 E;  1A1Z A;  4RHW E;  2HM2 Q;  4E9M A;  1DGN A;  2N00 A;  4M9X A;  2YVI A;  2YGS A;  4A2W A;  2L9M A;  4LWD A;  2F1S A;  2MN4 A;  2NSN A;  3KAT A;  4P4H I;  1DDF A;  2MJM A;  2YQF A;  2DBD A;  2YU0 A;  4N1L A;  2G7R A;  4JQW A;  4NQK A;  4O9L A;  3CL3 A;  2A9I A;  4O9F A;  4UZ0 A;  3MOP A;  4N1J A;  1FAD A;  2N7Z A;  2KN6 A;  4F42 A;  4O7Q A;  4IZA B;  4M9Z A;  1UCP A;  2KM6 A;  2OF5 A;  4N1K A;  3T6P A;  1WXP A;  2VGQ A;  3EZQ A;  2DBH A;  1Z6T A;  3YGS P;  1D2Z B;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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