1E7LA

Endonuclease vii (endovii) n62d mutant from phage t4
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
157
structure length
157
Chain Sequence
MLLTGKLYKEEKQKFYDAQNGKCLICQRELNPDVQANHLDHDHELNGPKAGKVRGLLCNLCDAAEGQMKHKFNRSGLKGQGVDYLEWLENLLTYLKSDYTQNNIHPNFVGDKSKEFSRLGKEEMMAEMLQRGFEYNESDTKTQLIASFKKQLRKSLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Flexibility in T4 Endonuclease Vii Revealed by Crystallography: Implications for Substrate Binding and Cleavage
pubmed doi rcsb
molecule tags Endonuclease
source organism Bacteriophage t4
molecule keywords RECOMBINATION ENDONUCLEASE VII
total genus 50
structure length 157
sequence length 157
chains with identical sequence B
ec nomenclature ec 3.1.22.4: Crossover junction endodeoxyribonuclease.
pdb deposition date 2000-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02945 Endonuclease_7 Recombination endonuclease VII
A PF09124 Endonuc-dimeris T4 recombination endonuclease VII, dimerisation
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.10 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 1e7lA02
3.40.1800.10 Alpha Beta 3-Layer(aba) Sandwich His-Me finger endonuclease fold His-Me finger endonucleases 1e7lA01
1E7LA 3GOXA 1A62A 2HJQA 1E7DA 2QNFA 3FC3A 1A8VA 1A63A 2QNCA 3L0OA 1EN7A 2A8VA
chains in the Genus database with same CATH superfamily
2ODCI 1KHCA 2WQGA 1A8VA 1GJJA 2ODGC 1A63A 2QNCA 3QKJA 1GL9B 1YNSA 2RNOA 3LLRA 3FLGA 2LC3A 4BITA 2N1UA 2QNFA 3FC3A 1H9EA 5CIUA 2JVWA 1JEIA 2KVUA 1JJRA 4UZWA 2KFVA 1A62A 2G80A 2W51A 1H1JS 1Y02A 1E7DA 2LD7A 2KVEA 1EN7A 2A8VA 2MPHA 1V66A 1E7LA 1GKUB 2KVDA 2RNNA 1PZWA 2HJQA 3GOXA 2DK4A 1ZBHA 3L0OA 2KDPA 1JEQA 1H9FA 1ZS9A 2KW9A
chains in the Genus database with same CATH topology
2ODCI 1A8VA 1GJJA 2ODGC 1A63A 2QNCA 1GL9B 1YNSA 2LC3A 3FC3A 2QNFA 1H9EA 1JEIA 2KFVA 1A62A 2G80A 2W51A 1Y02A 1E7DA 2LD7A 1EN7A 2A8VA 2MPHA 1E7LA 1GKUB 3GOXA 2HJQA 2DK4A 3L0OA 1H9FA 1ZS9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E7L A;  3GOX A;  1A62 A;  2HJQ A;  1E7D A;  2QNF A;  3FC3 A;  1A8V A;  1A63 A;  2QNC A;  3L0O A;  1EN7 A;  2A8V A; 
#chains in the Genus database with same CATH topology
 2ODC I;  1KHC A;  2WQG A;  1A8V A;  1GJJ A;  2ODG C;  1A63 A;  2QNC A;  3QKJ A;  1GL9 B;  1YNS A;  2RNO A;  3LLR A;  3FLG A;  2LC3 A;  4BIT A;  2N1U A;  2QNF A;  3FC3 A;  1H9E A;  5CIU A;  2JVW A;  1JEI A;  2KVU A;  1JJR A;  4UZW A;  2KFV A;  1A62 A;  2G80 A;  2W51 A;  1H1J S;  1Y02 A;  1E7D A;  2LD7 A;  2KVE A;  1EN7 A;  2A8V A;  2MPH A;  1V66 A;  1E7L A;  1GKU B;  2KVD A;  2RNN A;  1PZW A;  2HJQ A;  3GOX A;  2DK4 A;  1ZBH A;  3L0O A;  2KDP A;  1JEQ A;  1H9F A;  1ZS9 A;  2KW9 A; 
#chains in the Genus database with same CATH homology
 2ODC I;  1A8V A;  1GJJ A;  2ODG C;  1A63 A;  2QNC A;  1GL9 B;  1YNS A;  2LC3 A;  3FC3 A;  2QNF A;  1H9E A;  1JEI A;  2KFV A;  1A62 A;  2G80 A;  2W51 A;  1Y02 A;  1E7D A;  2LD7 A;  1EN7 A;  2A8V A;  2MPH A;  1E7L A;  1GKU B;  3GOX A;  2HJQ A;  2DK4 A;  3L0O A;  1H9F A;  1ZS9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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