1EQNA

E.coli primase catalytic core
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
315
structure length
315
Chain Sequence
RQTLYQLMDGLNTFYQQSLQQPVATSARQYLEKRGLSHEVIARFAIGFAPPGWDNVLKRFGGNPENRQSLIDAGMLVTNDQGRSYDRFRERVMFPIRDKRGRVIGFGGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPNRLLVVEGYMDVVALAQYGINYAVASLGTSTTADHIQLLFRATNNVICCYDGDRAGRDAAWRALETALPYMTDGRQLRFMFLPDGEDPDTLVRKEGKEAFEARMEQAMPLSAFLFNSLMPQVDLSTPDGRARLSTLALPLISQVPGETLRIYLRQELGNKLGILDDSQL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A TOPRIM domain in the crystal structure of the catalytic core of Escherichia coli primase confirms a structural link to DNA topoisomerases.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords DNA PRIMASE
total genus 87
structure length 315
sequence length 315
chains with identical sequence B, C, D, E
ec nomenclature ec 2.7.7.-:
pdb deposition date 2000-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
A PF10410 DnaB_bind DnaB-helicase binding domain of primase
A PF13155 Toprim_2 Toprim-like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 1eqnA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 1eqnA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 1eqnA01
1T6T1 1DDEA 4JCVA 4EDTA 4E2KA 1DD9A 2Q2EA 1EQNA 4O6PB 3B39A 4EDGA 2AU3A 1VDDA 4EDVA 4EE1A 3VDPA 5GUJA 2V1CA 1D3YA 4EDKA 3VDUA 2ZBKA 3VE5A 4O6OA 4EDRA
chains in the Genus database with same CATH superfamily
1ERCA 1T6T1 2NSWA 1DDEA 4JCVA 4EDTA 4E2KA 1DD9A 2Q2EA 1EQNA 4O6PB 3KLSA 2FCJA 3B39A 3CU7A 4EDGA 3KXRA 2AU3A 1VDDA 4EDVA 2ERLA 4EE1A 3VDPA 5GUJA 2LMKA 2B39A 2V1CA 1D3YA 4EDKA 2NSVA 3VDUA 2JMSA 2KC6A 2KK2A 2ZBKA 3VE5A 2I5RA 4O6OA 4EDRA
chains in the Genus database with same CATH topology
1ERCA 1T6T1 2NSWA 1DDEA 4JCVA 4EDTA 4E2KA 1DD9A 2Q2EA 1EQNA 4O6PB 3KLSA 3B39A 3CU7A 4EDGA 3KXRA 2AU3A 1VDDA 4EDVA 2ERLA 4EE1A 3VDPA 5GUJA 2LMKA 2B39A 2V1CA 1D3YA 4EDKA 2NSVA 3VDUA 2JMSA 2KC6A 2KK2A 2ZBKA 3VE5A 4O6OA 4EDRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T6T 1;  1DDE A;  4JCV A;  4EDT A;  4E2K A;  1DD9 A;  2Q2E A;  1EQN A;  4O6P B;  3B39 A;  4EDG A;  2AU3 A;  1VDD A;  4EDV A;  4EE1 A;  3VDP A;  5GUJ A;  2V1C A;  1D3Y A;  4EDK A;  3VDU A;  2ZBK A;  3VE5 A;  4O6O A;  4EDR A; 
#chains in the Genus database with same CATH topology
 1ERC A;  1T6T 1;  2NSW A;  1DDE A;  4JCV A;  4EDT A;  4E2K A;  1DD9 A;  2Q2E A;  1EQN A;  4O6P B;  3KLS A;  2FCJ A;  3B39 A;  3CU7 A;  4EDG A;  3KXR A;  2AU3 A;  1VDD A;  4EDV A;  2ERL A;  4EE1 A;  3VDP A;  5GUJ A;  2LMK A;  2B39 A;  2V1C A;  1D3Y A;  4EDK A;  2NSV A;  3VDU A;  2JMS A;  2KC6 A;  2KK2 A;  2ZBK A;  3VE5 A;  2I5R A;  4O6O A;  4EDR A; 
#chains in the Genus database with same CATH homology
 1ERC A;  1T6T 1;  2NSW A;  1DDE A;  4JCV A;  4EDT A;  4E2K A;  1DD9 A;  2Q2E A;  1EQN A;  4O6P B;  3KLS A;  3B39 A;  3CU7 A;  4EDG A;  3KXR A;  2AU3 A;  1VDD A;  4EDV A;  2ERL A;  4EE1 A;  3VDP A;  5GUJ A;  2LMK A;  2B39 A;  2V1C A;  1D3Y A;  4EDK A;  2NSV A;  3VDU A;  2JMS A;  2KC6 A;  2KK2 A;  2ZBK A;  3VE5 A;  4O6O A;  4EDR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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