1EQYS

Complex between rabbit muscle alpha-actin: human gelsolin domain 1
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
125
structure length
125
Chain Sequence
MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTCLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of gelsolin segment 1-actin complex and the mechanism of filament severing.
pubmed doi rcsb
molecule tags Contractile protein
source organism Homo sapiens
molecule keywords GELSOLIN
total genus 38
structure length 125
sequence length 125
ec nomenclature
pdb deposition date 2000-04-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1eqyS00
1DEJS 3EH2A 2NUTB 2QTVA 5KYWB 3A5LS 5KYXB 5A1MA 5KYNA 1M2OA 1QPVA 1T2LA 2NUPA 5L6WC 3A5OS 2FF3A 5FAEA 3EGXB 2VILA 3FG7A 2NUTA 1TVJA 1AHQA 1H1VG 4CBXG 1F7SA 1J72A 2W0IA 3EFOA 5KYUB 1CFYA 2MV2A 2MOTA 1M4JA 1V6FA 1PD0A 1WM4A 1X67A 2VACA 4PKIG 3CJBG 3TU5B 1Q8XA 2NUPB 1SVRA 3EH1A 1PD1A 5KYUA 1JHWA 1NLVG 3EG9B 1NPHA 5DD2A 3FFKA 3EFOB 2L72A 3L50A 4PKHB 4JD2H 1NMDG 1T3YA 1COFA 1T44G 3EGDA 3FFNA 3EG9A 1AK7A 4BEX1 5KYYA 1CNUA 3A5NS 4Z94G 2LJ8A 1P8XA 4CBUG 1M2VA 1T3XA 5FAFA 1SVQA 1PCXA 4PKGG 3FG6A 1WNJA 1C0FS 2XF1A 2KVKA 1WFSA 2I2QA 4KEDA 2FH1A 1TMWA 3EGDB 5HVKB 1NM1G 3CJCG 4CBWG 5KYYB 4S10C 1M2VB 1RGIG 2D8BA 1ESVS 5IVUA 3DAWB 1C0GS 5HVKD 2LLFA 4KEFA 2FH2A 1D4XG 1EQYS 2MP4A 1UDMA 1AK6A 2FH4A 1SVYA 1Q8GA 1VKKA 2FGHA 1P8ZG 2LXXA 3Q2BA 2HD7A 4KEEA 1MDUA 2FH3A 5KYWA 5KYXA 1HQZ1 1YVNG 1VFQA 1D0NA 2VIKA 2FF6G 3CIPG 3EGXA 1KCQA 3CI5G 4LIZA 1YAGG 2XFAA 3A5MS
chains in the Genus database with same CATH superfamily
1DEJS 3EH2A 2NUTB 2QTVA 5KYWB 3A5LS 5KYXB 5A1MA 5KYNA 1M2OA 1QPVA 1T2LA 2NUPA 5L6WC 3A5OS 2FF3A 5FAEA 3EGXB 2VILA 3FG7A 2NUTA 1TVJA 1AHQA 1H1VG 4CBXG 1F7SA 1J72A 2W0IA 3EFOA 5KYUB 1CFYA 2MV2A 2MOTA 1M4JA 1V6FA 1PD0A 1WM4A 1X67A 2VACA 4PKIG 3CJBG 3TU5B 1Q8XA 2NUPB 1SVRA 3EH1A 1PD1A 5KYUA 1JHWA 1NLVG 3EG9B 1NPHA 5DD2A 3FFKA 3EFOB 2L72A 3L50A 4PKHB 4JD2H 1NMDG 1T3YA 1COFA 1T44G 3EGDA 3FFNA 3EG9A 1AK7A 4BEX1 3DA7A 5KYYA 1CNUA 3A5NS 4Z94G 2LJ8A 1P8XA 4CBUG 1M2VA 1T3XA 5FAFA 1SVQA 1PCXA 4PKGG 3FG6A 1WNJA 1C0FS 2XF1A 2KVKA 1WFSA 2I2QA 4KEDA 2FH1A 1TMWA 3EGDB 5HVKB 1NM1G 3CJCG 4CBWG 5KYYB 4S10C 1M2VB 1RGIG 2D8BA 1ESVS 5IVUA 3DAWB 1C0GS 5HVKD 2LLFA 4KEFA 2FH2A 1D4XG 1EQYS 2MP4A 1UDMA 1AK6A 2FH4A 1SVYA 1Q8GA 1VKKA 2FGHA 1P8ZG 2LXXA 3Q2BA 2HD7A 4KEEA 1MDUA 2FH3A 5KYWA 5KYXA 1HQZ1 1YVNG 1VFQA 1D0NA 2VIKA 2FF6G 3CIPG 3EGXA 1KCQA 3CI5G 4LIZA 1YAGG 2XFAA 3A5MS
chains in the Genus database with same CATH topology
1DEJS 3EH2A 2NUTB 2QTVA 5KYWB 3A5LS 5KYXB 5A1MA 5KYNA 1M2OA 1QPVA 1T2LA 2NUPA 5L6WC 3A5OS 2FF3A 5FAEA 3EGXB 2VILA 3FG7A 2NUTA 1TVJA 1AHQA 1H1VG 4CBXG 1F7SA 1J72A 2W0IA 3EFOA 5KYUB 1CFYA 2MV2A 2MOTA 1M4JA 1V6FA 1PD0A 1WM4A 1X67A 2VACA 4PKIG 3CJBG 3TU5B 1Q8XA 2NUPB 1SVRA 3EH1A 1PD1A 5KYUA 1JHWA 1NLVG 3EG9B 1NPHA 5DD2A 3FFKA 3EFOB 2L72A 3L50A 4PKHB 4JD2H 1NMDG 1T3YA 1COFA 1T44G 3EGDA 3FFNA 3EG9A 1AK7A 4BEX1 3DA7A 5KYYA 1CNUA 3A5NS 4Z94G 2LJ8A 1P8XA 4CBUG 1M2VA 1T3XA 5FAFA 1SVQA 1PCXA 4PKGG 3FG6A 1WNJA 1C0FS 2XF1A 2KVKA 1WFSA 2I2QA 4KEDA 2FH1A 1TMWA 3EGDB 5HVKB 1NM1G 3CJCG 4CBWG 5KYYB 4S10C 1M2VB 1RGIG 2D8BA 1ESVS 5IVUA 3DAWB 1C0GS 5HVKD 2LLFA 4KEFA 2FH2A 1D4XG 1EQYS 2MP4A 1UDMA 1AK6A 2FH4A 1SVYA 1Q8GA 1VKKA 2FGHA 1P8ZG 2LXXA 3Q2BA 2HD7A 4KEEA 1MDUA 2FH3A 5KYWA 5KYXA 1HQZ1 1YVNG 1VFQA 1D0NA 2VIKA 2FF6G 3CIPG 3EGXA 1KCQA 3CI5G 4LIZA 1YAGG 2XFAA 3A5MS
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DEJ S;  3EH2 A;  2NUT B;  2QTV A;  5KYW B;  3A5L S;  5KYX B;  5A1M A;  5KYN A;  1M2O A;  1QPV A;  1T2L A;  2NUP A;  5L6W C;  3A5O S;  2FF3 A;  5FAE A;  3EGX B;  2VIL A;  3FG7 A;  2NUT A;  1TVJ A;  1AHQ A;  1H1V G;  4CBX G;  1F7S A;  1J72 A;  2W0I A;  3EFO A;  5KYU B;  1CFY A;  2MV2 A;  2MOT A;  1M4J A;  1V6F A;  1PD0 A;  1WM4 A;  1X67 A;  2VAC A;  4PKI G;  3CJB G;  3TU5 B;  1Q8X A;  2NUP B;  1SVR A;  3EH1 A;  1PD1 A;  5KYU A;  1JHW A;  1NLV G;  3EG9 B;  1NPH A;  5DD2 A;  3FFK A;  3EFO B;  2L72 A;  3L50 A;  4PKH B;  4JD2 H;  1NMD G;  1T3Y A;  1COF A;  1T44 G;  3EGD A;  3FFN A;  3EG9 A;  1AK7 A;  4BEX 1;  5KYY A;  1CNU A;  3A5N S;  4Z94 G;  2LJ8 A;  1P8X A;  4CBU G;  1M2V A;  1T3X A;  5FAF A;  1SVQ A;  1PCX A;  4PKG G;  3FG6 A;  1WNJ A;  1C0F S;  2XF1 A;  2KVK A;  1WFS A;  2I2Q A;  4KED A;  2FH1 A;  1TMW A;  3EGD B;  5HVK B;  1NM1 G;  3CJC G;  4CBW G;  5KYY B;  4S10 C;  1M2V B;  1RGI G;  2D8B A;  1ESV S;  5IVU A;  3DAW B;  1C0G S;  5HVK D;  2LLF A;  4KEF A;  2FH2 A;  1D4X G;  1EQY S;  2MP4 A;  1UDM A;  1AK6 A;  2FH4 A;  1SVY A;  1Q8G A;  1VKK A;  2FGH A;  1P8Z G;  2LXX A;  3Q2B A;  2HD7 A;  4KEE A;  1MDU A;  2FH3 A;  5KYW A;  5KYX A;  1HQZ 1;  1YVN G;  1VFQ A;  1D0N A;  2VIK A;  2FF6 G;  3CIP G;  3EGX A;  1KCQ A;  3CI5 G;  4LIZ A;  1YAG G;  2XFA A;  3A5M S; 
#chains in the Genus database with same CATH topology
 1DEJ S;  3EH2 A;  2NUT B;  2QTV A;  5KYW B;  3A5L S;  5KYX B;  5A1M A;  5KYN A;  1M2O A;  1QPV A;  1T2L A;  2NUP A;  5L6W C;  3A5O S;  2FF3 A;  5FAE A;  3EGX B;  2VIL A;  3FG7 A;  2NUT A;  1TVJ A;  1AHQ A;  1H1V G;  4CBX G;  1F7S A;  1J72 A;  2W0I A;  3EFO A;  5KYU B;  1CFY A;  2MV2 A;  2MOT A;  1M4J A;  1V6F A;  1PD0 A;  1WM4 A;  1X67 A;  2VAC A;  4PKI G;  3CJB G;  3TU5 B;  1Q8X A;  2NUP B;  1SVR A;  3EH1 A;  1PD1 A;  5KYU A;  1JHW A;  1NLV G;  3EG9 B;  1NPH A;  5DD2 A;  3FFK A;  3EFO B;  2L72 A;  3L50 A;  4PKH B;  4JD2 H;  1NMD G;  1T3Y A;  1COF A;  1T44 G;  3EGD A;  3FFN A;  3EG9 A;  1AK7 A;  4BEX 1;  3DA7 A;  5KYY A;  1CNU A;  3A5N S;  4Z94 G;  2LJ8 A;  1P8X A;  4CBU G;  1M2V A;  1T3X A;  5FAF A;  1SVQ A;  1PCX A;  4PKG G;  3FG6 A;  1WNJ A;  1C0F S;  2XF1 A;  2KVK A;  1WFS A;  2I2Q A;  4KED A;  2FH1 A;  1TMW A;  3EGD B;  5HVK B;  1NM1 G;  3CJC G;  4CBW G;  5KYY B;  4S10 C;  1M2V B;  1RGI G;  2D8B A;  1ESV S;  5IVU A;  3DAW B;  1C0G S;  5HVK D;  2LLF A;  4KEF A;  2FH2 A;  1D4X G;  1EQY S;  2MP4 A;  1UDM A;  1AK6 A;  2FH4 A;  1SVY A;  1Q8G A;  1VKK A;  2FGH A;  1P8Z G;  2LXX A;  3Q2B A;  2HD7 A;  4KEE A;  1MDU A;  2FH3 A;  5KYW A;  5KYX A;  1HQZ 1;  1YVN G;  1VFQ A;  1D0N A;  2VIK A;  2FF6 G;  3CIP G;  3EGX A;  1KCQ A;  3CI5 G;  4LIZ A;  1YAG G;  2XFA A;  3A5M S; 
#chains in the Genus database with same CATH homology
 1DEJ S;  3EH2 A;  2NUT B;  2QTV A;  5KYW B;  3A5L S;  5KYX B;  5A1M A;  5KYN A;  1M2O A;  1QPV A;  1T2L A;  2NUP A;  5L6W C;  3A5O S;  2FF3 A;  5FAE A;  3EGX B;  2VIL A;  3FG7 A;  2NUT A;  1TVJ A;  1AHQ A;  1H1V G;  4CBX G;  1F7S A;  1J72 A;  2W0I A;  3EFO A;  5KYU B;  1CFY A;  2MV2 A;  2MOT A;  1M4J A;  1V6F A;  1PD0 A;  1WM4 A;  1X67 A;  2VAC A;  4PKI G;  3CJB G;  3TU5 B;  1Q8X A;  2NUP B;  1SVR A;  3EH1 A;  1PD1 A;  5KYU A;  1JHW A;  1NLV G;  3EG9 B;  1NPH A;  5DD2 A;  3FFK A;  3EFO B;  2L72 A;  3L50 A;  4PKH B;  4JD2 H;  1NMD G;  1T3Y A;  1COF A;  1T44 G;  3EGD A;  3FFN A;  3EG9 A;  1AK7 A;  4BEX 1;  3DA7 A;  5KYY A;  1CNU A;  3A5N S;  4Z94 G;  2LJ8 A;  1P8X A;  4CBU G;  1M2V A;  1T3X A;  5FAF A;  1SVQ A;  1PCX A;  4PKG G;  3FG6 A;  1WNJ A;  1C0F S;  2XF1 A;  2KVK A;  1WFS A;  2I2Q A;  4KED A;  2FH1 A;  1TMW A;  3EGD B;  5HVK B;  1NM1 G;  3CJC G;  4CBW G;  5KYY B;  4S10 C;  1M2V B;  1RGI G;  2D8B A;  1ESV S;  5IVU A;  3DAW B;  1C0G S;  5HVK D;  2LLF A;  4KEF A;  2FH2 A;  1D4X G;  1EQY S;  2MP4 A;  1UDM A;  1AK6 A;  2FH4 A;  1SVY A;  1Q8G A;  1VKK A;  2FGH A;  1P8Z G;  2LXX A;  3Q2B A;  2HD7 A;  4KEE A;  1MDU A;  2FH3 A;  5KYW A;  5KYX A;  1HQZ 1;  1YVN G;  1VFQ A;  1D0N A;  2VIK A;  2FF6 G;  3CIP G;  3EGX A;  1KCQ A;  3CI5 G;  4LIZ A;  1YAG G;  2XFA A;  3A5M S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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