The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
37
|
sequence length |
157
|
structure length |
157
|
Chain Sequence |
WSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIV
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
publication title |
Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains.
pubmed doi rcsb |
molecule tags |
Cell adhesion protein
|
source organism |
Homo sapiens
|
molecule keywords |
HUMAN E-SELECTIN
|
total genus |
37
|
structure length |
157
|
sequence length |
157
|
ec nomenclature | |
pdb deposition date | 1994-06-03 |
chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
---|---|---|---|
A | PF00008 | EGF | EGF-like domain |
A | PF00059 | Lectin_C | Lectin C-type domain |
cath code
| Class | Architecture | Topology | Homology | Domain |
---|---|---|---|---|---|
Alpha Beta | Roll | Mannose-Binding Protein A; Chain A | Mannose-Binding Protein A, subunit A |
#chains in the Genus database with same CATH superfamily 1P1Z D; 4M18 A; 1T8C A; 2ORJ A; 1RDN 1; 2KV3 A; 4J6Q A; 2ZQK A; 1BCJ 1; 1KMB 1; 2GO0 A; 3PAQ A; 4CAJ A; 1UEX A; 1UEX B; 1FM5 A; 1X2W A; 1B6E A; 1AFA 1; 1RJH A; 1X2W B; 3PBF A; 2AFP A; 1OZ7 A; 2OX9 A; 1BYF A; 1BV4 A; 2H2R A; 1U0O A; 1OZ7 B; 3ALT A; 3C22 A; 4N35 A; 4KMB 1; 1U0O B; 3G83 A; 1KZD 1; 3K7B A; 1XPH A; 1KWY A; 1IOD B; 1EGG A; 3ALU A; 1HYR A; 5J6G G; 1IJK C; 4MTH A; 3CDG F; 1H8U A; 1RDM 1; 1KWU A; 1HQ8 A; 4QKI A; 3C8J A; 1PWB A; 3IKR A; 1Y17 A; 4QKJ A; 3WSR A; 3PAK A; 4J6P A; 4J6J A; 1Y17 B; 2MTI A; 4C9F A; 3WH2 A; 4WRE A; 1U0N C; 1YPO A; 4ZES A; 3HUP A; 4ZRV A; 4GJX A; 4M17 A; 1KOE A; 2BPE A; 3GPR C; 1CWV A; 1FIF A; 1JZN A; 1G1Q A; 1KWT A; 3C8K D; 1BUU A; 1WT9 A; 4WUX A; 1K9I A; 2CL8 A; 1WT9 B; 3FD4 A; 4YMD A; 1MUQ A; 3WHD A; 1TN3 A; 3DBZ A; 3FF8 C; 1UMR A; 4CSY A; 3G8L A; 3P5D A; 1RDJ 1; 2YHF A; 4KI1 E; 3ZHG A; 5FFR A; 1FVU A; 1YPU A; 1HUP A; 1FVU B; 2E3X B; 4N34 A; 3KMB 1; 4YLI A; 2RID A; 1RDL 1; 4G96 A; 1RTM 1; 3CFW A; 2IT5 A; 2OX8 A; 4J6M A; 1E87 A; 3GPR D; 2BPH A; 4QKG A; 4PDC A; 3P7F A; 1JA3 A; 3VYJ A; 5B1X A; 1KZB 1; 3PAR A; 3ALS A; 1BNL A; 1J34 A; 3P5E A; 1X2T A; 3P7G A; 1J34 B; 4J6L A; 1O7B T; 1X2T B; 5K8Y A; 1G1T A; 1BCH 1; 1KZA 1; 3IKQ A; 1KCG A; 4WQQ A; 1DY2 A; 3WWK C; 4M1G A; 1K9J A; 3NCW A; 3UBU A; 1IOD A; 1UKM A; 3WH3 A; 3P5H A; 3UBU B; 1XAR A; 1UKM B; 3VLG A; 2BPD A; 1V4L A; 1IXX A; 1KX1 A; 1P4L D; 3VYK A; 1V4L B; 3IKN A; 1IXX B; 1RDI 1; 1SL5 A; 1TDQ B; 1YTT A; 4AK8 A; 2RIB A; 5LGK E; 5FFS A; 1YXK A; 3P5I A; 1G1S A; 2C6U A; 4GJ0 A; 1R13 A; 3WWK B; 3FF9 A; 1MPU A; 1GZ2 A; 1O7C T; 1KWV A; 3P7H A; 2RIA A; 5B1R A; 4N37 A; 1DV8 A; 2XR6 A; 1IJK B; 1E8I A; 1SB2 A; 4WR9 A; 1SB2 B; 1HTN A; 1C3A A; 1UOS A; 3CDG E; 3CCK A; 1C3A B; 1UOS B; 1LIT A; 1QO3 C; 1SL4 A; 1U0N B; 3RS1 A; 2VUV A; 3IKP A; 4QKH A; 1T8D A; 4C16 A; 2XR5 A; 1KZC 1; 3GPR A; 4N32 A; 3GPR B; 3G81 A; 3P5F A; 2VUZ A; 3CAD A; 4WCO A; 4N33 A; 1PW9 A; 3FF7 C; 3BX4 A; 1SL6 A; 4N36 A; 3BX4 B; 4J6N A; 5B1W A; 1KWW A; 4N38 A; 4GK1 A; 1KWZ A; 4ZRW A; 1JWI A; 3BDW A; 3WBR A; 1JWI B; 3BDW B; 1KZE 1; 4WRC A; 3WBQ A; 2RIC A; 2KMB 1; 1KG0 C; 1KX0 A; 1EGI A; 5KTH A; 1FIH A; 4DN8 A; 1TLG A; 2GGX A; 4GKO G; 2ORK A; 2I83 A; 1UV0 A; 1J35 A; 3T3A A; 2ZIB A; 1KWX A; 1J35 B; 1DY1 A; 1MSB A; 1BJ3 A; 3WBP A; 3P5G A; 1BJ3 B; 4ZET A; 1YPQ A; 1YXJ A; 3WWK A; 4KZV A; 1R14 A; 4WUW A; 1G1R A; 2BRS A; 2PY2 A; 4S0U A; 1QDD A; 2ZWK A; 4GI0 A; 4E52 A; 1RDK 1; 2RIE A; 3NCX A; 3G84 A; 4IOP A; 4G9A A; 2LS8 A; 3VPP A; 4IOP B; 1AFD 1; 1ESL A; 5F2Q A; 5KTI A; 3G8K A; 4LQF A; 1F02 I; 3L9J C; 1UMR C; 1WK1 A; 4LU5 A; 1V7P A; 4UWW A; 2E3X C; 1V7P B; 1DY0 A; 1F00 I; 2IT6 A; 1B08 A; 2M94 A; 1WMY A; 2MSB A; 1WMZ A; 4PP8 A; 2OS9 A; 4EZM G; 1E5U I; 4KZW A; 2PF5 A; 2VRP A; 4WRF A; 2H2T B; 2VRP B; 2N40 A; 5M62 A; 5FFT A; 3M9Z A; 2GGU A; 4UXM A; 4J6K A; 3KQG A; 1RDO 1; 3ZHG D; 1AFB 1; #chains in the Genus database with same CATH topology 1P1Z D; 4M18 A; 1T8C A; 2ORJ A; 1RDN 1; 2KV3 A; 4J6Q A; 2ZQK A; 1BCJ 1; 1KMB 1; 2GO0 A; 3PAQ A; 4CAJ A; 1UEX A; 1UEX B; 1FM5 A; 1X2W A; 1B6E A; 1AFA 1; 1RJH A; 1X2W B; 3PBF A; 2AFP A; 1OZ7 A; 2OX9 A; 1BYF A; 1BV4 A; 2H2R A; 1U0O A; 1OZ7 B; 3ALT A; 3C22 A; 4N35 A; 4KMB 1; 1U0O B; 3G83 A; 1KZD 1; 3K7B A; 1XPH A; 1KWY A; 1IOD B; 1EGG A; 3ALU A; 1HYR A; 5J6G G; 1IJK C; 4MTH A; 3CDG F; 1H8U A; 1RDM 1; 1KWU A; 1HQ8 A; 4QKI A; 3C8J A; 1PWB A; 3IKR A; 1Y17 A; 4QKJ A; 3WSR A; 3PAK A; 4J6P A; 4J6J A; 1Y17 B; 2MTI A; 4C9F A; 3WH2 A; 4WRE A; 1U0N C; 1YPO A; 4ZES A; 3HUP A; 4ZRV A; 4GJX A; 4M17 A; 1KOE A; 2BPE A; 3GPR C; 1CWV A; 1FIF A; 1JZN A; 1G1Q A; 1KWT A; 3C8K D; 1BUU A; 1WT9 A; 4WUX A; 1K9I A; 2CL8 A; 1WT9 B; 3FD4 A; 4YMD A; 1MUQ A; 3WHD A; 1TN3 A; 3DBZ A; 3FF8 C; 1UMR A; 4CSY A; 3G8L A; 3P5D A; 1RDJ 1; 2YHF A; 4KI1 E; 3ZHG A; 5FFR A; 1FVU A; 1YPU A; 1HUP A; 1FVU B; 2E3X B; 4N34 A; 3KMB 1; 4YLI A; 2RID A; 1RDL 1; 4G96 A; 1RTM 1; 3CFW A; 2IT5 A; 2OX8 A; 4J6M A; 1E87 A; 3GPR D; 2BPH A; 4QKG A; 4PDC A; 3P7F A; 1JA3 A; 3VYJ A; 5B1X A; 1KZB 1; 3PAR A; 3ALS A; 1BNL A; 1J34 A; 3P5E A; 1X2T A; 3P7G A; 1J34 B; 4J6L A; 1O7B T; 1X2T B; 5K8Y A; 1G1T A; 1BCH 1; 1KZA 1; 3IKQ A; 1KCG A; 4WQQ A; 1DY2 A; 3WWK C; 4M1G A; 1K9J A; 3NCW A; 3UBU A; 1IOD A; 1UKM A; 3WH3 A; 3P5H A; 3UBU B; 1XAR A; 1UKM B; 3VLG A; 2BPD A; 1V4L A; 1IXX A; 1KX1 A; 1P4L D; 3VYK A; 1V4L B; 3IKN A; 1IXX B; 1RDI 1; 1SL5 A; 1TDQ B; 1YTT A; 4AK8 A; 2RIB A; 5LGK E; 5FFS A; 1YXK A; 3P5I A; 1G1S A; 2C6U A; 4GJ0 A; 1R13 A; 3WWK B; 3FF9 A; 1MPU A; 1GZ2 A; 1O7C T; 1KWV A; 3P7H A; 2RIA A; 5B1R A; 4N37 A; 1DV8 A; 2XR6 A; 1IJK B; 1E8I A; 1SB2 A; 4WR9 A; 1SB2 B; 1HTN A; 1C3A A; 1UOS A; 3CDG E; 3CCK A; 1C3A B; 1UOS B; 1LIT A; 1QO3 C; 1SL4 A; 1U0N B; 3RS1 A; 2VUV A; 3IKP A; 4QKH A; 1T8D A; 4C16 A; 2XR5 A; 1KZC 1; 3GPR A; 4N32 A; 3GPR B; 3G81 A; 3P5F A; 2VUZ A; 3CAD A; 4WCO A; 4N33 A; 1PW9 A; 3FF7 C; 3BX4 A; 1SL6 A; 4N36 A; 3BX4 B; 4J6N A; 5B1W A; 1KWW A; 4N38 A; 4GK1 A; 1KWZ A; 4ZRW A; 1JWI A; 3BDW A; 3WBR A; 1JWI B; 3BDW B; 1KZE 1; 4WRC A; 3WBQ A; 2RIC A; 2KMB 1; 1KG0 C; 1KX0 A; 1EGI A; 5KTH A; 1FIH A; 4DN8 A; 1TLG A; 2GGX A; 4GKO G; 2ORK A; 2I83 A; 1UV0 A; 1J35 A; 3T3A A; 2ZIB A; 1KWX A; 1J35 B; 1DY1 A; 1MSB A; 1BJ3 A; 3WBP A; 3P5G A; 1BJ3 B; 4ZET A; 1YPQ A; 1YXJ A; 3WWK A; 4KZV A; 1R14 A; 4WUW A; 1G1R A; 2BRS A; 2PY2 A; 4S0U A; 1QDD A; 2ZWK A; 4GI0 A; 4E52 A; 1RDK 1; 2RIE A; 3NCX A; 3G84 A; 4IOP A; 4G9A A; 2LS8 A; 3VPP A; 4IOP B; 1AFD 1; 1ESL A; 5F2Q A; 5KTI A; 3G8K A; 4LQF A; 1F02 I; 3L9J C; 1UMR C; 1WK1 A; 4LU5 A; 1V7P A; 4UWW A; 2E3X C; 1V7P B; 1DY0 A; 1F00 I; 2IT6 A; 1B08 A; 2M94 A; 1WMY A; 2MSB A; 1WMZ A; 4PP8 A; 2OS9 A; 4EZM G; 1E5U I; 4KZW A; 2PF5 A; 2VRP A; 4WRF A; 2H2T B; 2VRP B; 2N40 A; 5M62 A; 5FFT A; 3M9Z A; 2GGU A; 4UXM A; 4J6K A; 3KQG A; 1RDO 1; 3ZHG D; 1AFB 1; #chains in the Genus database with same CATH homology 1P1Z D; 4M18 A; 1T8C A; 2ORJ A; 1RDN 1; 2KV3 A; 4J6Q A; 2ZQK A; 1BCJ 1; 1KMB 1; 2GO0 A; 3PAQ A; 4CAJ A; 1UEX A; 1UEX B; 1FM5 A; 1X2W A; 1B6E A; 1AFA 1; 1RJH A; 1X2W B; 3PBF A; 2AFP A; 1OZ7 A; 2OX9 A; 1BYF A; 1BV4 A; 2H2R A; 1U0O A; 1OZ7 B; 3ALT A; 3C22 A; 4N35 A; 4KMB 1; 1U0O B; 3G83 A; 1KZD 1; 3K7B A; 1XPH A; 1KWY A; 1IOD B; 1EGG A; 3ALU A; 1HYR A; 5J6G G; 1IJK C; 4MTH A; 3CDG F; 1H8U A; 1RDM 1; 1KWU A; 1HQ8 A; 4QKI A; 3C8J A; 1PWB A; 3IKR A; 1Y17 A; 4QKJ A; 3WSR A; 3PAK A; 4J6P A; 4J6J A; 1Y17 B; 2MTI A; 4C9F A; 3WH2 A; 4WRE A; 1U0N C; 1YPO A; 4ZES A; 3HUP A; 4ZRV A; 4GJX A; 4M17 A; 1KOE A; 2BPE A; 3GPR C; 1CWV A; 1FIF A; 1JZN A; 1G1Q A; 1KWT A; 3C8K D; 1BUU A; 1WT9 A; 4WUX A; 1K9I A; 2CL8 A; 1WT9 B; 3FD4 A; 4YMD A; 1MUQ A; 3WHD A; 1TN3 A; 3DBZ A; 3FF8 C; 1UMR A; 4CSY A; 3G8L A; 3P5D A; 1RDJ 1; 2YHF A; 4KI1 E; 3ZHG A; 5FFR A; 1FVU A; 1YPU A; 1HUP A; 1FVU B; 2E3X B; 4N34 A; 3KMB 1; 4YLI A; 2RID A; 1RDL 1; 4G96 A; 1RTM 1; 3CFW A; 2IT5 A; 2OX8 A; 4J6M A; 1E87 A; 3GPR D; 2BPH A; 4QKG A; 4PDC A; 3P7F A; 1JA3 A; 3VYJ A; 5B1X A; 1KZB 1; 3PAR A; 3ALS A; 1BNL A; 1J34 A; 3P5E A; 1X2T A; 3P7G A; 1J34 B; 4J6L A; 1O7B T; 1X2T B; 5K8Y A; 1G1T A; 1BCH 1; 1KZA 1; 3IKQ A; 1KCG A; 4WQQ A; 1DY2 A; 3WWK C; 4M1G A; 1K9J A; 3NCW A; 3UBU A; 1IOD A; 1UKM A; 3WH3 A; 3P5H A; 3UBU B; 1XAR A; 1UKM B; 3VLG A; 2BPD A; 1V4L A; 1IXX A; 1KX1 A; 1P4L D; 3VYK A; 1V4L B; 3IKN A; 1IXX B; 1RDI 1; 1SL5 A; 1TDQ B; 1YTT A; 4AK8 A; 2RIB A; 5LGK E; 5FFS A; 1YXK A; 3P5I A; 1G1S A; 2C6U A; 4GJ0 A; 1R13 A; 3WWK B; 3FF9 A; 1MPU A; 1GZ2 A; 1O7C T; 1KWV A; 3P7H A; 2RIA A; 5B1R A; 4N37 A; 1DV8 A; 2XR6 A; 1IJK B; 1E8I A; 1SB2 A; 4WR9 A; 1SB2 B; 1HTN A; 1C3A A; 1UOS A; 3CDG E; 3CCK A; 1C3A B; 1UOS B; 1LIT A; 1QO3 C; 1SL4 A; 1U0N B; 3RS1 A; 2VUV A; 3IKP A; 4QKH A; 1T8D A; 4C16 A; 2XR5 A; 1KZC 1; 3GPR A; 4N32 A; 3GPR B; 3G81 A; 3P5F A; 2VUZ A; 3CAD A; 4WCO A; 4N33 A; 1PW9 A; 3FF7 C; 3BX4 A; 1SL6 A; 4N36 A; 3BX4 B; 4J6N A; 5B1W A; 1KWW A; 4N38 A; 4GK1 A; 1KWZ A; 4ZRW A; 1JWI A; 3BDW A; 3WBR A; 1JWI B; 3BDW B; 1KZE 1; 4WRC A; 3WBQ A; 2RIC A; 2KMB 1; 1KG0 C; 1KX0 A; 1EGI A; 5KTH A; 1FIH A; 4DN8 A; 1TLG A; 2GGX A; 4GKO G; 2ORK A; 2I83 A; 1UV0 A; 1J35 A; 3T3A A; 2ZIB A; 1KWX A; 1J35 B; 1DY1 A; 1MSB A; 1BJ3 A; 3WBP A; 3P5G A; 1BJ3 B; 4ZET A; 1YPQ A; 1YXJ A; 3WWK A; 4KZV A; 1R14 A; 4WUW A; 1G1R A; 2BRS A; 2PY2 A; 4S0U A; 1QDD A; 2ZWK A; 4GI0 A; 4E52 A; 1RDK 1; 2RIE A; 3NCX A; 3G84 A; 4IOP A; 4G9A A; 2LS8 A; 3VPP A; 4IOP B; 1AFD 1; 1ESL A; 5F2Q A; 5KTI A; 3G8K A; 4LQF A; 1F02 I; 3L9J C; 1UMR C; 1WK1 A; 4LU5 A; 1V7P A; 4UWW A; 2E3X C; 1V7P B; 1DY0 A; 1F00 I; 2IT6 A; 1B08 A; 2M94 A; 1WMY A; 2MSB A; 1WMZ A; 4PP8 A; 2OS9 A; 4EZM G; 1E5U I; 4KZW A; 2PF5 A; 2VRP A; 4WRF A; 2H2T B; 2VRP B; 2N40 A; 5M62 A; 5FFT A; 3M9Z A; 2GGU A; 4UXM A; 4J6K A; 3KQG A; 1RDO 1; 3ZHG D; 1AFB 1;
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