1EZBA

Amino terminal domain of enzyme i from escherichia coli, nmr, 17 structures
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
259
structure length
259
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ENZYME I
publication title Solution structure of the 30 kDa N-terminal domain of enzyme I of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system by multidimensional NMR.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Phosphotransferase
total genus 69
structure length 259
sequence length 259
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1997-01-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 1ezbA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 1ezbA01
1EZBA 2EZAA 1KBLA 2MP0A 2HI6A 2X0SA 2DIKA 1EZAA 5JVLA 3T0TA 1JDEA 1VBGA 2EZCA 1ZYMA 2E28A 1KC7A 3T05A 1GGOA 3EZEA 1VBHA 2HROA 1DIKA 2HWGA 3EZAA 2R82A 2EZBA 2OLSA 3EZBA 2FM4A 3T07A
chains in the Genus database with same CATH superfamily
2A68D 1K83A 2XEGA 1T6JA 3GTJA 4OMEA 2JBJA 1JDEA 1W27A 4BABA 3H0GA 2LYIA 2XEIA 5F1YA 3GTQA 4C85A 5D29A 4CQ5A 1WCMA 4NGQA 1EZBA 3GTMA 3RBUA 2FIOA 3KASA 3BHXA 1KC7A 1JDBC 3T5MA 3TLYA 2C6PA 4CZ1A 3SJXA 4CDJA 2A6ED 4CEHA 1TWGA 3EZAA 1Y1VA 1NBWA 5F09A 4C8PA 4P4EA 2YJTA 2MP0A 2C5QA 2JA5A 3SJEA 4TJXA 2LPJA 4OC4A 2YIIA 4EYSA 2K3OA 3T05A 2FIPA 3SJGA 2X0PA 4IIXA 5IB9A 1C30B 3LRDA 2A6HD 3LR8A 3K4IA 4X3RA 1KBLA 2D0OA 2HI6A 3S9LA 2VK9A 2Y0NA 3BI0A 2XEJA 4CEJA 3GJZA 3TLAA 2AUNA 3KRVA 1WVMA 2HWGA 5F9MA 4C9AA 2MX8A 2NVXA 2K3NA 3G23A 4C6GA 3D7DA 2B0AA 4C9EA 3TLEA 4E5SA 4V2QA 4KNGE 2NVYA 3D7HA 3SR3A 2R93A 1SMYD 4OC3A 1ZL0A 3TLGA 4C5RA 1Y2MA 1SFOA 4FBSA 4C5UA 2AQLA 2R7ZA 2JA6A 3TLGB 1V6CA 3EZEA 4C5SA 2PVWA 4NGRA 4YN3A 2JA7A 2X0QA 3S9MA 1R61A 5IZ2A 3U44A 2R92A 3IIBA 3T07A 4MCQA 3K9TA 1T36B 4M8DA 2C6GA 3TLZA 4NGMA 4NGSA 2B63A 1R9TA 2EZCA 4MCPA 3TLBA 4V2RA 1ZYRD 3TYXA 1Y9ZA 2BE5D 4MCSA 4P4FA 2EZBA 3D7FA 4C8AA 4MJXA 2DIKA 1VBGA 2C6CA 1CX8A 4P4DA 1I50A 1M6VB 1C3OB 5FD8A 2D0PA 4IIYA 2F5JA 4NGPA 1IW7D 4COGA 1TWAA 1EZAA 4W9YA 1YNJD 3IWWA 4C8UA 1NXJA 3FECA 2AUMA 3U1BA 2VUMA 2CIJA 3SJFA 1Q5XA 4MCRA 2E2IA 3C8OA 2R82A 2LPIA 3EZBA 4OC5A 2EZAA 3T0TA 4C84A 1ZYMA 4C2MA 5ELYA 2A69D 4OC1A 3I6SA 3NOJA 2XEFA 4CDKA 4E94A 3GTOA 2OLSA 1XF1A 1CE8B 3BI1A 1I6VD 3GTGA 1DE4C 3I74A 2E28A 2YJVA 4C9VA 2OOTA 1VI4A 1CS0B 3VTAA 4JYWA 4LQGA 4MI1A 3D7GA 3EIFA 4C8CA 4P4IA 3S9NA 2K3QA 1ZRSA 3LR6A 1VBHA 4JVOA 4BAAA 4CO9A 3FEDA 4OC0A 4P44A 1TWHA 3FF3A 1I3QA 3FEEA 4H1HA 1Z8LA 5JVLA 2LTHA 3GTLA 1J3LA 4C99A 3FKIA 2E2HA 1T6PA 1TWFA 1Y1WA 4INJA 1TWCA 2MX9A 2O5JD 2JBKA 1KEEB 4P45A 4C9UA 4NGTA 2OR4A 4P4BA 2PVVA 5JYBA 2N3EA 2MQAA 1YNND 2GP4A 1DIKA 3BXMA 3NZ4A 4CEIA 4COBA 2LKMB 2FM4A 3TLCA 2X0SA 4C8FA 1GGOA 4NGNA 2HROA 1BXRB 4C9RA 4C86A 4J0NA 2EK9A 5IR2A 2YU9A 4TJVA 2X0OA 3ICUA 4QIWA 2EK8A 3GTKA 3LR2A 1A9XB 1HQMD 3GTPA 3U4QA 4TWEA 3CQZA 4OC2A 5K99A 4C8TA 4JZ0A 2CW0D 5F5XA 2N1DB 2PCNA 4P4JA
chains in the Genus database with same CATH topology
1EZBA 2EZAA 1KBLA 2MP0A 2HI6A 2X0SA 2DIKA 1EZAA 5JVLA 3T0TA 1JDEA 1VBGA 2EZCA 1ZYMA 2E28A 1KC7A 3T05A 1GGOA 3EZEA 1VBHA 2HROA 1DIKA 2HWGA 3EZAA 2R82A 2EZBA 2OLSA 3EZBA 2FM4A 3T07A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EZB A;  2EZA A;  1KBL A;  2MP0 A;  2HI6 A;  2X0S A;  2DIK A;  1EZA A;  5JVL A;  3T0T A;  1JDE A;  1VBG A;  2EZC A;  1ZYM A;  2E28 A;  1KC7 A;  3T05 A;  1GGO A;  3EZE A;  1VBH A;  2HRO A;  1DIK A;  2HWG A;  3EZA A;  2R82 A;  2EZB A;  2OLS A;  3EZB A;  2FM4 A;  3T07 A; 
#chains in the Genus database with same CATH topology
 2A68 D;  1K83 A;  2XEG A;  1T6J A;  3GTJ A;  4OME A;  2JBJ A;  1JDE A;  1W27 A;  4BAB A;  3H0G A;  2LYI A;  2XEI A;  5F1Y A;  3GTQ A;  4C85 A;  5D29 A;  4CQ5 A;  1WCM A;  4NGQ A;  1EZB A;  3GTM A;  3RBU A;  2FIO A;  3KAS A;  3BHX A;  1KC7 A;  1JDB C;  3T5M A;  3TLY A;  2C6P A;  4CZ1 A;  3SJX A;  4CDJ A;  2A6E D;  4CEH A;  1TWG A;  3EZA A;  1Y1V A;  1NBW A;  5F09 A;  4C8P A;  4P4E A;  2YJT A;  2MP0 A;  2C5Q A;  2JA5 A;  3SJE A;  4TJX A;  2LPJ A;  4OC4 A;  2YII A;  4EYS A;  2K3O A;  3T05 A;  2FIP A;  3SJG A;  2X0P A;  4IIX A;  5IB9 A;  1C30 B;  3LRD A;  2A6H D;  3LR8 A;  3K4I A;  4X3R A;  1KBL A;  2D0O A;  2HI6 A;  3S9L A;  2VK9 A;  2Y0N A;  3BI0 A;  2XEJ A;  4CEJ A;  3GJZ A;  3TLA A;  2AUN A;  3KRV A;  1WVM A;  2HWG A;  5F9M A;  4C9A A;  2MX8 A;  2NVX A;  2K3N A;  3G23 A;  4C6G A;  3D7D A;  2B0A A;  4C9E A;  3TLE A;  4E5S A;  4V2Q A;  4KNG E;  2NVY A;  3D7H A;  3SR3 A;  2R93 A;  1SMY D;  4OC3 A;  1ZL0 A;  3TLG A;  4C5R A;  1Y2M A;  1SFO A;  4FBS A;  4C5U A;  2AQL A;  2R7Z A;  2JA6 A;  3TLG B;  1V6C A;  3EZE A;  4C5S A;  2PVW A;  4NGR A;  4YN3 A;  2JA7 A;  2X0Q A;  3S9M A;  1R61 A;  5IZ2 A;  3U44 A;  2R92 A;  3IIB A;  3T07 A;  4MCQ A;  3K9T A;  1T36 B;  4M8D A;  2C6G A;  3TLZ A;  4NGM A;  4NGS A;  2B63 A;  1R9T A;  2EZC A;  4MCP A;  3TLB A;  4V2R A;  1ZYR D;  3TYX A;  1Y9Z A;  2BE5 D;  4MCS A;  4P4F A;  2EZB A;  3D7F A;  4C8A A;  4MJX A;  2DIK A;  1VBG A;  2C6C A;  1CX8 A;  4P4D A;  1I50 A;  1M6V B;  1C3O B;  5FD8 A;  2D0P A;  4IIY A;  2F5J A;  4NGP A;  1IW7 D;  4COG A;  1TWA A;  1EZA A;  4W9Y A;  1YNJ D;  3IWW A;  4C8U A;  1NXJ A;  3FEC A;  2AUM A;  3U1B A;  2VUM A;  2CIJ A;  3SJF A;  1Q5X A;  4MCR A;  2E2I A;  3C8O A;  2R82 A;  2LPI A;  3EZB A;  4OC5 A;  2EZA A;  3T0T A;  4C84 A;  1ZYM A;  4C2M A;  5ELY A;  2A69 D;  4OC1 A;  3I6S A;  3NOJ A;  2XEF A;  4CDK A;  4E94 A;  3GTO A;  2OLS A;  1XF1 A;  1CE8 B;  3BI1 A;  1I6V D;  3GTG A;  1DE4 C;  3I74 A;  2E28 A;  2YJV A;  4C9V A;  2OOT A;  1VI4 A;  1CS0 B;  3VTA A;  4JYW A;  4LQG A;  4MI1 A;  3D7G A;  3EIF A;  4C8C A;  4P4I A;  3S9N A;  2K3Q A;  1ZRS A;  3LR6 A;  1VBH A;  4JVO A;  4BAA A;  4CO9 A;  3FED A;  4OC0 A;  4P44 A;  1TWH A;  3FF3 A;  1I3Q A;  3FEE A;  4H1H A;  1Z8L A;  5JVL A;  2LTH A;  3GTL A;  1J3L A;  4C99 A;  3FKI A;  2E2H A;  1T6P A;  1TWF A;  1Y1W A;  4INJ A;  1TWC A;  2MX9 A;  2O5J D;  2JBK A;  1KEE B;  4P45 A;  4C9U A;  4NGT A;  2OR4 A;  4P4B A;  2PVV A;  5JYB A;  2N3E A;  2MQA A;  1YNN D;  2GP4 A;  1DIK A;  3BXM A;  3NZ4 A;  4CEI A;  4COB A;  2LKM B;  2FM4 A;  3TLC A;  2X0S A;  4C8F A;  1GGO A;  4NGN A;  2HRO A;  1BXR B;  4C9R A;  4C86 A;  4J0N A;  2EK9 A;  5IR2 A;  2YU9 A;  4TJV A;  2X0O A;  3ICU A;  4QIW A;  2EK8 A;  3GTK A;  3LR2 A;  1A9X B;  1HQM D;  3GTP A;  3U4Q A;  4TWE A;  3CQZ A;  4OC2 A;  5K99 A;  4C8T A;  4JZ0 A;  2CW0 D;  5F5X A;  2N1D B;  2PCN A;  4P4J A; 
#chains in the Genus database with same CATH homology
 1EZB A;  2EZA A;  1KBL A;  2MP0 A;  2HI6 A;  2X0S A;  2DIK A;  1EZA A;  5JVL A;  3T0T A;  1JDE A;  1VBG A;  2EZC A;  1ZYM A;  2E28 A;  1KC7 A;  3T05 A;  1GGO A;  3EZE A;  1VBH A;  2HRO A;  1DIK A;  2HWG A;  3EZA A;  2R82 A;  2EZB A;  2OLS A;  3EZB A;  2FM4 A;  3T07 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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