The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
174
|
sequence length |
535
|
structure length |
520
|
Chain Sequence |
GADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDDDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTKVLALKVDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEINFETRGKRGQDAMYEYMAQACACINLDWDVIRDKTKTKIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEFHQTALEHPELSELKTVTGTNPVFAGANYAAWAVNVAQVIDSETADNLEKTTAALSILPGIGSVMGIADGAVHHNTEEIVAQSIALSSLMVAQAIPLVGELIGFAAYNFVESIINLFQVVHNSYNRPAYSPGHKTQPFLHDGYAVSWNTVEDSIIRTGFQGESGHDIKITAENTPLPIAGVLLPTIPGKLDVNKSKTHISVNGRKIRMRCRAIDGDVTFCRPKSPVYVGNGVHANLHVAFHRSSSEKIHSNEISSDSIGVLGYQKTVDHTKVNSKLSLFFEIKS
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Characterization of High-Order Oligomerization and Energetics in Diphtheria Toxin
pubmed rcsb |
| molecule tags |
Toxin
|
| molecule keywords |
DIPHTHERIA TOXIN
|
| total genus |
174
|
| structure length |
520
|
| sequence length |
535
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase. |
| pdb deposition date | 2000-05-16 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01324 | Diphtheria_R | Diphtheria toxin, R domain |
| A | PF02763 | Diphtheria_C | Diphtheria toxin, C domain |
| A | PF02764 | Diphtheria_T | Diphtheria toxin, T domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Globin-like | Diphtheria toxin, translocation domain | ||
| Mainly Beta | Sandwich | Immunoglobulin-like | Diphtheria toxin, receptor-binding domain | ||
| Alpha Beta | Alpha-Beta Complex | Diphtheria Toxin; domain 1 | Diphtheria Toxin, domain 1 |
