1F82A

Botulinum neurotoxin type b catalytic domain
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
424
structure length
424
Chain Sequence
PVTINNFNYNDPIDNNNIIMMEPPFARGTGRYYKAFKITDRIWIIPERYTFGYKPEDFNKSSGIFNRDVCEYYDPDYLNTNDKKNIFLQTMIKLFNRIKSKPLGEKLLEMIINGIPYLGDRRVPLEEFNTNIASVTVNKLISNPGEVERKKGIFANLIIFGPGPVLNENETIDIGIQNHFASREGFGGIMQMKFCPEYVSVFNNVQENKGASIFNRRGYFSDPALILMHELIHVLHGLYGIKVDDLPIVPNEKKFFMQSTDAIQAEELYTFGGQDPSIITPSTDKSIYDKVLQNFRGIVDRLNKVLVCISDPNININIYKNKFKDKYKFVEDSEGKYSIDVESFDKLYKSLMFGFTETNIAENYKIKTRASYFSDSLPPVKIKNLLDNEIYTIEEGFNISDKDMEKEYRGQNKAINKQAYEEIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution.
pubmed doi rcsb
molecule tags Toxin,hydrolase
source organism Clostridium botulinum
molecule keywords BOTULINUM NEUROTOXIN TYPE B
total genus 127
structure length 424
sequence length 424
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2000-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01742 Peptidase_M27 Clostridial neurotoxin zinc protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1240.10 Alpha Beta Alpha-Beta Complex Zincin-like Metalloproteases ("zincins"), catalytic domain like 1f82A00
5BQNA 3DS9A 2IMBA 3FIIA 1YVGA 3BOKA 3BONA 1Z7HA 3V0AB 2ISHA 3ZUSA 2ETFA 3ZUQA 1S0CA 1ZL5A 1G9CA 2ISEA 1S0FA 2ISGA 3C8BA 2NYYA 3D3XA 3QW7A 3BWIA 1T3AA 3V0BB 4J1LA 1ZKWA 1E1HA 1G9AA 2NP0A 1XTGA 1F82A 4ZJXA 2ILPA 3ZURA 2G7NA 3QW5A 3DSEA 1S0BA 4KS6A 1S0EA 2IMCA 2G7PA 3DEBA 1S0GA 1G9DA 3QW6A 1EPWA 2A97A 3QIYA 1ZL6A 2A8AA 3BOOA 2G7KA 3NF3A 3DDBA 2QN0A 4EJ5A 3VUOA 2W2DA 3V0BA 3C8AA 3K3QB 1ZB7A 4ZKTB 3DDAA 2G7QA 1G9BA 3FFZA 1S0DA 1T3CA 3QW8A 2IMAA 3V0AA 3C88A 1XTFA 3BTAA 2FPQA 1ZN3A 4ELCA 2NZ9A 3FIEA 4HEVA 3C89A 2XHLA 3QIXA 1F31A 1ZKXA 1I1EA 3QJ0A 5BQMA 3QIZA 4KUFA 4EL4A 4KTXA
chains in the Genus database with same CATH superfamily
5BQNA 3DS9A 2IMBA 3FIIA 1YVGA 2EJQA 3BOKA 3BONA 1Z7HA 3V0AB 4IL3A 2ISHA 3ZUSA 2ETFA 3ZUQA 1S0CA 1ZL5A 1G9CA 2ISEA 4QHFA 1S0FA 2ISGA 3C8BA 2NYYA 3D3XA 3QW7A 3BWIA 1T3AA 3V0BB 4J1LA 1ZKWA 1E1HA 1G9AA 2NP0A 1XTGA 1F82A 4ZJXA 2ILPA 3ZURA 2G7NA 3QW5A 3DSEA 1S0BA 4KS6A 4JIUA 1S0EA 2IMCA 2G7PA 3DEBA 2YPTA 1S0GA 1G9DA 3QW6A 1EPWA 2A97A 3QIYA 4AW6A 1ZL6A 2A8AA 3BOOA 2G7KA 3CQBA 3NF3A 4JIXA 3DDBA 2QN0A 4EJ5A 3VUOA 2W2DA 3V0BA 3C8AA 3K3QB 1ZB7A 4ZKTB 3DDAA 2G7QA 1G9BA 3FFZA 1S0DA 1T3CA 3QW8A 2IMAA 3V0AA 3C88A 1XTFA 3E11A 3BTAA 2FPQA 1ZN3A 4ELCA 2NZ9A 3FIEA 4HEVA 3C89A 2XHLA 3QIXA 1F31A 1ZKXA 1I1EA 3QJ0A 5BQMA 3QIZA 4KUFA 4EL4A 4KTXA
chains in the Genus database with same CATH topology
5BQNA 3DS9A 2IMBA 3FIIA 1YVGA 3BOKA 3BONA 1Z7HA 3V0AB 2ISHA 3ZUSA 2ETFA 3ZUQA 1S0CA 1ZL5A 1G9CA 2ISEA 1S0FA 2ISGA 3C8BA 2NYYA 3D3XA 3QW7A 3BWIA 1T3AA 3V0BB 4J1LA 1ZKWA 1E1HA 1G9AA 2NP0A 1XTGA 1F82A 4ZJXA 2ILPA 3ZURA 2G7NA 3QW5A 3DSEA 1S0BA 4KS6A 1S0EA 2IMCA 2G7PA 3DEBA 1S0GA 1G9DA 3QW6A 1EPWA 2A97A 3QIYA 1ZL6A 2A8AA 3BOOA 2G7KA 3NF3A 3DDBA 2QN0A 4EJ5A 3VUOA 2W2DA 3V0BA 3C8AA 3K3QB 1ZB7A 4ZKTB 3DDAA 2G7QA 1G9BA 3FFZA 1S0DA 1T3CA 3QW8A 2IMAA 3V0AA 3C88A 1XTFA 3BTAA 2FPQA 1ZN3A 4ELCA 2NZ9A 3FIEA 4HEVA 3C89A 2XHLA 3QIXA 1F31A 1ZKXA 1I1EA 3QJ0A 5BQMA 3QIZA 4KUFA 4EL4A 4KTXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BQN A;  3DS9 A;  2IMB A;  3FII A;  1YVG A;  3BOK A;  3BON A;  1Z7H A;  3V0A B;  2ISH A;  3ZUS A;  2ETF A;  3ZUQ A;  1S0C A;  1ZL5 A;  1G9C A;  2ISE A;  1S0F A;  2ISG A;  3C8B A;  2NYY A;  3D3X A;  3QW7 A;  3BWI A;  1T3A A;  3V0B B;  4J1L A;  1ZKW A;  1E1H A;  1G9A A;  2NP0 A;  1XTG A;  1F82 A;  4ZJX A;  2ILP A;  3ZUR A;  2G7N A;  3QW5 A;  3DSE A;  1S0B A;  4KS6 A;  1S0E A;  2IMC A;  2G7P A;  3DEB A;  1S0G A;  1G9D A;  3QW6 A;  1EPW A;  2A97 A;  3QIY A;  1ZL6 A;  2A8A A;  3BOO A;  2G7K A;  3NF3 A;  3DDB A;  2QN0 A;  4EJ5 A;  3VUO A;  2W2D A;  3V0B A;  3C8A A;  3K3Q B;  1ZB7 A;  4ZKT B;  3DDA A;  2G7Q A;  1G9B A;  3FFZ A;  1S0D A;  1T3C A;  3QW8 A;  2IMA A;  3V0A A;  3C88 A;  1XTF A;  3BTA A;  2FPQ A;  1ZN3 A;  4ELC A;  2NZ9 A;  3FIE A;  4HEV A;  3C89 A;  2XHL A;  3QIX A;  1F31 A;  1ZKX A;  1I1E A;  3QJ0 A;  5BQM A;  3QIZ A;  4KUF A;  4EL4 A;  4KTX A; 
#chains in the Genus database with same CATH topology
 5BQN A;  3DS9 A;  2IMB A;  3FII A;  1YVG A;  2EJQ A;  3BOK A;  3BON A;  1Z7H A;  3V0A B;  4IL3 A;  2ISH A;  3ZUS A;  2ETF A;  3ZUQ A;  1S0C A;  1ZL5 A;  1G9C A;  2ISE A;  4QHF A;  1S0F A;  2ISG A;  3C8B A;  2NYY A;  3D3X A;  3QW7 A;  3BWI A;  1T3A A;  3V0B B;  4J1L A;  1ZKW A;  1E1H A;  1G9A A;  2NP0 A;  1XTG A;  1F82 A;  4ZJX A;  2ILP A;  3ZUR A;  2G7N A;  3QW5 A;  3DSE A;  1S0B A;  4KS6 A;  4JIU A;  1S0E A;  2IMC A;  2G7P A;  3DEB A;  2YPT A;  1S0G A;  1G9D A;  3QW6 A;  1EPW A;  2A97 A;  3QIY A;  4AW6 A;  1ZL6 A;  2A8A A;  3BOO A;  2G7K A;  3CQB A;  3NF3 A;  4JIX A;  3DDB A;  2QN0 A;  4EJ5 A;  3VUO A;  2W2D A;  3V0B A;  3C8A A;  3K3Q B;  1ZB7 A;  4ZKT B;  3DDA A;  2G7Q A;  1G9B A;  3FFZ A;  1S0D A;  1T3C A;  3QW8 A;  2IMA A;  3V0A A;  3C88 A;  1XTF A;  3E11 A;  3BTA A;  2FPQ A;  1ZN3 A;  4ELC A;  2NZ9 A;  3FIE A;  4HEV A;  3C89 A;  2XHL A;  3QIX A;  1F31 A;  1ZKX A;  1I1E A;  3QJ0 A;  5BQM A;  3QIZ A;  4KUF A;  4EL4 A;  4KTX A; 
#chains in the Genus database with same CATH homology
 5BQN A;  3DS9 A;  2IMB A;  3FII A;  1YVG A;  3BOK A;  3BON A;  1Z7H A;  3V0A B;  2ISH A;  3ZUS A;  2ETF A;  3ZUQ A;  1S0C A;  1ZL5 A;  1G9C A;  2ISE A;  1S0F A;  2ISG A;  3C8B A;  2NYY A;  3D3X A;  3QW7 A;  3BWI A;  1T3A A;  3V0B B;  4J1L A;  1ZKW A;  1E1H A;  1G9A A;  2NP0 A;  1XTG A;  1F82 A;  4ZJX A;  2ILP A;  3ZUR A;  2G7N A;  3QW5 A;  3DSE A;  1S0B A;  4KS6 A;  1S0E A;  2IMC A;  2G7P A;  3DEB A;  1S0G A;  1G9D A;  3QW6 A;  1EPW A;  2A97 A;  3QIY A;  1ZL6 A;  2A8A A;  3BOO A;  2G7K A;  3NF3 A;  3DDB A;  2QN0 A;  4EJ5 A;  3VUO A;  2W2D A;  3V0B A;  3C8A A;  3K3Q B;  1ZB7 A;  4ZKT B;  3DDA A;  2G7Q A;  1G9B A;  3FFZ A;  1S0D A;  1T3C A;  3QW8 A;  2IMA A;  3V0A A;  3C88 A;  1XTF A;  3BTA A;  2FPQ A;  1ZN3 A;  4ELC A;  2NZ9 A;  3FIE A;  4HEV A;  3C89 A;  2XHL A;  3QIX A;  1F31 A;  1ZKX A;  1I1E A;  3QJ0 A;  5BQM A;  3QIZ A;  4KUF A;  4EL4 A;  4KTX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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