1FARA

Raf-1 cysteine rich domain, nmr, minimized average structure
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
52
structure length
52
Chain Sequence
LTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site.
pubmed doi rcsb
molecule tags Serine/threonine protein kinase
source organism Homo sapiens
molecule keywords RAF-1
total genus 2
structure length 52
sequence length 52
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 1996-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00130 C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1farA00
2J87A 1FAQA 1XA6A 3E2IA 2QQEA 3UGIA 5FUYA 1PTQA 1XX6A 1PTRA 1Y8FA 2QPOA 1KBEA 2WVJA 5FUVA 3UGDA 2YUUA 5FUWA 2ENZA 2ORWA 1TBOA 1FARA 2B8TA 2JA1A 2ELIA 4B6DA 2ORVA 3UEJA 2ENNA 2FNFX 3UFFA 3CXLA 4FKDA 2VRWB 2QQ0A 2E73A 1XBTA 3KY9A 1TBNA 3BJIA 3UEYA 1RFHA 4UXJA 4UXIA 3UGLA 1KBFA 1W4RA 2J9RA 5FUXA 4L9MA 2UZ3A 2ROWA 4UXHA 2DB6A 2GVIA 1R79A
chains in the Genus database with same CATH superfamily
4JCVE 1XA6A 2K9HA 3E2IA 2CWGA 1P9ZA 2QPOA 1XX6A 1PTRA 2KMPA 2WCYA 4OVOA 1AN1I 1K7VA 1X4SA 1YU6C 5FUVA 2CWHA 2RIJA 2SGPI 1VDDA 3OVOA 2N71A 1SGQI 1CGII 3VDPA 1CE3A 1YTPA 2XRCA 3CXLA 3OXGA 4FKDA 1ULMA 2SGQI 5HI7A 1XBTA 2OZUA 4WP4A 3TOBA 1OMTA 3BJIA 3UOEA 4UXJA 1UHAA 4UXIA 5J8FA 2N17A 1W4RA 1K7TA 2ARPF 2KCXA 1TBQR 2ODDA 1KBFA 1M8CA 2OD1A 1UUCA 3QAHA 2OU2A 1MJBA 2WGCA 1OVOA 3R5CA 3SGBI 3OXLA 3VDUA 3TO6A 4SGBI 1S20A 2LUYA 1SGEI 3R5BA 1WGTA 2UVOA 1TGSI 1DS2I 1PTQA 2JZMA 2BUSA 2L8EA 2N1AB 1KBEA 2GKVA 5E3PA 7WGAA 2OVOA 3UGDA 1HEVA 1CT0I 5FUWA 3SEKC 3VE5A 5J8CA 1FARA 1MJ9A 1Y1BA 2JW6A 3TOAA 1IY5A 3R5DA 3UEJA 1BMOA 2QQCA 2X3TA 1DS3I 3UFFA 2VRWB 2QQ0A 3FSYA 1BUSA 1MJAA 1Z7KB 3KY9A 1ULNA 2PQ8A 5E3QA 1IW4A 1TBRR 3UGLA 1HJAI 2J9RA 1R0RI 2P6AC 3D00A 3QWPA 3TJQA 4DNCA 1N13A 4HGUA 1V1HA 1OYVI 1FY7A 3FSXA 2JYYA 1OMUA 3B4VC 3FC3A 4GI3C 1M8BA 9WGAA 2J87A 2NU1I 5EX3A 1P9GA 1PPFI 1UVGA 2A20A 1K7UA 2GKRI 2KMOA 2QQEA 5HQ8A 1Y8FA 1TIHA 2SGDI 5EX0A 3MEKA 4E1RA 1CSOI 2JXDA 1SGNI 1TBOA 2KMRA 2B8TA 1PCEA 2M5XA 2ELIA 4B6DA 1Z2IA 2Y0MA 2GIVA 1ULKA 4A24A 1SGRI 1IY6A 2FNFX 2V53A 1FYBA 2NU3I 1CGJI 1NUBA 5E3RA 1U5KA 1RFHA 2CWFA 3UEYA 2KMQA 3RU0A 1SGPI 4L9MA 2UZ3A 3OL0A 2NU0I 2ROWA 2NU2I 1TURA 1LR9A 2V1CC 4MPIA 3SGQI 2X52A 2V1CA 3PDNA 1WTJA 1CT4I 2DB6A 1R79A 1CT2I 3E59A 3TO7A 1TUSA 3R5AA 1UVFA 1FAQA 3TO9A 4AMLA 3GOXA 1WKXA 2L7XA 2NU4I 5DAEA 5FUYA 2WVJA 3UGIA 4E1PA 2RC4A 2LB7A 2QQDA 2YUUA 1TOTA 2ENZA 2GKTI 2ORWA 1H0ZA 2JA1A 1PJUA 2ORVA 1MT1A 1V1IA 1CHOI 2B0UC 2ENNA 2ERWA 2N52A 2YQPA 2SGFI 1X74A 2DIPA 1KMAA 1SGYI 1HDLA 2E73A 2E5RA 1Q9BA 3OXFA 2LEOA 2F3CI 1TBNA 1WGCA 5CCLA 3HH2C 3QTLD 2W0TA 5FUXA 1SGDI 1Y1CA 1LR7A 1W3SA 4UXHA 5CCMA 5JHWC 1NXUA 2GVIA 1HPTA 2DKVA 2CJSC 2SGEI 1LR8A
chains in the Genus database with same CATH topology
4JCVE 1XA6A 2K9HA 3E2IA 2QPOA 1XX6A 1PTRA 2KMPA 2WCYA 4OVOA 1AN1I 1YU6C 1X4SA 5FUVA 2SGPI 1VDDA 3OVOA 2N71A 1SGQI 1CGII 3VDPA 1CE3A 1YTPA 2XRCA 3CXLA 3OXGA 4FKDA 2SGQI 5HI7A 1XBTA 1OMTA 3BJIA 4UXJA 4UXIA 1KBFA 2N17A 1W4RA 2ARPF 2KCXA 1TBQR 2ODDA 1M8CA 2OD1A 1UUCA 3SGBI 1OVOA 3OXLA 3VDUA 4SGBI 2LUYA 1SGEI 1TGSI 1DS2I 1PTQA 2JZMA 2BUSA 2L8EA 2N1AB 1KBEA 2GKVA 2OVOA 3UGDA 1CT0I 5FUWA 3SEKC 3VE5A 1FARA 1Y1BA 2JW6A 1IY5A 3UEJA 1BMOA 2QQCA 1DS3I 3UFFA 2VRWB 2QQ0A 1BUSA 1Z7KB 3KY9A 1IW4A 1TBRR 3UGLA 1HJAI 2J9RA 1R0RI 2P6AC 3D00A 3QWPA 3TJQA 1N13A 4HGUA 1V1HA 1OYVI 2JYYA 1OMUA 3B4VC 3FC3A 4GI3C 1M8BA 2J87A 2NU1I 5EX3A 1PPFI 1UVGA 2A20A 2GKRI 2QQEA 2KMOA 5HQ8A 1Y8FA 1TIHA 2SGDI 5EX0A 3MEKA 4E1RA 1CSOI 2JXDA 1SGNI 1TBOA 2KMRA 2B8TA 1PCEA 2M5XA 2ELIA 4B6DA 4A24A 1SGRI 1IY6A 2FNFX 2V53A 1FYBA 2NU3I 1CGJI 1NUBA 3UEYA 1U5KA 1RFHA 2KMQA 3RU0A 1SGPI 4L9MA 2UZ3A 3OL0A 2NU0I 2ROWA 2NU2I 1TURA 1LR9A 2V1CC 3SGQI 3PDNA 2V1CA 1CT4I 2DB6A 1R79A 1CT2I 3E59A 1TUSA 1UVFA 1FAQA 3GOXA 2L7XA 2NU4I 5DAEA 5FUYA 3UGIA 2WVJA 4E1PA 2QQDA 2YUUA 1TOTA 2ENZA 2GKTI 2ORWA 1H0ZA 2JA1A 1PJUA 2ORVA 1MT1A 1V1IA 1CHOI 2B0UC 2ENNA 2ERWA 2N52A 2YQPA 2SGFI 1X74A 2DIPA 1KMAA 1SGYI 1HDLA 2E73A 2E5RA 3OXFA 5CCLA 2LEOA 2F3CI 1TBNA 3HH2C 3QTLD 2W0TA 5FUXA 1SGDI 1Y1CA 1LR7A 1W3SA 4UXHA 5CCMA 5JHWC 2GVIA 1HPTA 2CJSC 2SGEI 1LR8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J87 A;  1FAQ A;  1XA6 A;  3E2I A;  2QQE A;  3UGI A;  5FUY A;  1PTQ A;  1XX6 A;  1PTR A;  1Y8F A;  2QPO A;  1KBE A;  2WVJ A;  5FUV A;  3UGD A;  2YUU A;  5FUW A;  2ENZ A;  2ORW A;  1TBO A;  1FAR A;  2B8T A;  2JA1 A;  2ELI A;  4B6D A;  2ORV A;  3UEJ A;  2ENN A;  2FNF X;  3UFF A;  3CXL A;  4FKD A;  2VRW B;  2QQ0 A;  2E73 A;  1XBT A;  3KY9 A;  1TBN A;  3BJI A;  3UEY A;  1RFH A;  4UXJ A;  4UXI A;  3UGL A;  1KBF A;  1W4R A;  2J9R A;  5FUX A;  4L9M A;  2UZ3 A;  2ROW A;  4UXH A;  2DB6 A;  2GVI A;  1R79 A; 
#chains in the Genus database with same CATH topology
 4JCV E;  1XA6 A;  2K9H A;  3E2I A;  2CWG A;  1P9Z A;  2QPO A;  1XX6 A;  1PTR A;  2KMP A;  2WCY A;  4OVO A;  1AN1 I;  1K7V A;  1X4S A;  1YU6 C;  5FUV A;  2CWH A;  2RIJ A;  2SGP I;  1VDD A;  3OVO A;  2N71 A;  1SGQ I;  1CGI I;  3VDP A;  1CE3 A;  1YTP A;  2XRC A;  3CXL A;  3OXG A;  4FKD A;  1ULM A;  2SGQ I;  5HI7 A;  1XBT A;  2OZU A;  4WP4 A;  3TOB A;  1OMT A;  3BJI A;  3UOE A;  4UXJ A;  1UHA A;  4UXI A;  5J8F A;  2N17 A;  1W4R A;  1K7T A;  2ARP F;  2KCX A;  1TBQ R;  2ODD A;  1KBF A;  1M8C A;  2OD1 A;  1UUC A;  3QAH A;  2OU2 A;  1MJB A;  2WGC A;  1OVO A;  3R5C A;  3SGB I;  3OXL A;  3VDU A;  3TO6 A;  4SGB I;  1S20 A;  2LUY A;  1SGE I;  3R5B A;  1WGT A;  2UVO A;  1TGS I;  1DS2 I;  1PTQ A;  2JZM A;  2BUS A;  2L8E A;  2N1A B;  1KBE A;  2GKV A;  5E3P A;  7WGA A;  2OVO A;  3UGD A;  1HEV A;  1CT0 I;  5FUW A;  3SEK C;  3VE5 A;  5J8C A;  1FAR A;  1MJ9 A;  1Y1B A;  2JW6 A;  3TOA A;  1IY5 A;  3R5D A;  3UEJ A;  1BMO A;  2QQC A;  2X3T A;  1DS3 I;  3UFF A;  2VRW B;  2QQ0 A;  3FSY A;  1BUS A;  1MJA A;  1Z7K B;  3KY9 A;  1ULN A;  2PQ8 A;  5E3Q A;  1IW4 A;  1TBR R;  3UGL A;  1HJA I;  2J9R A;  1R0R I;  2P6A C;  3D00 A;  3QWP A;  3TJQ A;  4DNC A;  1N13 A;  4HGU A;  1V1H A;  1OYV I;  1FY7 A;  3FSX A;  2JYY A;  1OMU A;  3B4V C;  3FC3 A;  4GI3 C;  1M8B A;  9WGA A;  2J87 A;  2NU1 I;  5EX3 A;  1P9G A;  1PPF I;  1UVG A;  2A20 A;  1K7U A;  2GKR I;  2KMO A;  2QQE A;  5HQ8 A;  1Y8F A;  1TIH A;  2SGD I;  5EX0 A;  3MEK A;  4E1R A;  1CSO I;  2JXD A;  1SGN I;  1TBO A;  2KMR A;  2B8T A;  1PCE A;  2M5X A;  2ELI A;  4B6D A;  1Z2I A;  2Y0M A;  2GIV A;  1ULK A;  4A24 A;  1SGR I;  1IY6 A;  2FNF X;  2V53 A;  1FYB A;  2NU3 I;  1CGJ I;  1NUB A;  5E3R A;  1U5K A;  1RFH A;  2CWF A;  3UEY A;  2KMQ A;  3RU0 A;  1SGP I;  4L9M A;  2UZ3 A;  3OL0 A;  2NU0 I;  2ROW A;  2NU2 I;  1TUR A;  1LR9 A;  2V1C C;  4MPI A;  3SGQ I;  2X52 A;  2V1C A;  3PDN A;  1WTJ A;  1CT4 I;  2DB6 A;  1R79 A;  1CT2 I;  3E59 A;  3TO7 A;  1TUS A;  3R5A A;  1UVF A;  1FAQ A;  3TO9 A;  4AML A;  3GOX A;  1WKX A;  2L7X A;  2NU4 I;  5DAE A;  5FUY A;  2WVJ A;  3UGI A;  4E1P A;  2RC4 A;  2LB7 A;  2QQD A;  2YUU A;  1TOT A;  2ENZ A;  2GKT I;  2ORW A;  1H0Z A;  2JA1 A;  1PJU A;  2ORV A;  1MT1 A;  1V1I A;  1CHO I;  2B0U C;  2ENN A;  2ERW A;  2N52 A;  2YQP A;  2SGF I;  1X74 A;  2DIP A;  1KMA A;  1SGY I;  1HDL A;  2E73 A;  2E5R A;  1Q9B A;  3OXF A;  2LEO A;  2F3C I;  1TBN A;  1WGC A;  5CCL A;  3HH2 C;  3QTL D;  2W0T A;  5FUX A;  1SGD I;  1Y1C A;  1LR7 A;  1W3S A;  4UXH A;  5CCM A;  5JHW C;  1NXU A;  2GVI A;  1HPT A;  2DKV A;  2CJS C;  2SGE I;  1LR8 A; 
#chains in the Genus database with same CATH homology
 4JCV E;  1XA6 A;  2K9H A;  3E2I A;  2QPO A;  1XX6 A;  1PTR A;  2KMP A;  2WCY A;  4OVO A;  1AN1 I;  1YU6 C;  1X4S A;  5FUV A;  2SGP I;  1VDD A;  3OVO A;  2N71 A;  1SGQ I;  1CGI I;  3VDP A;  1CE3 A;  1YTP A;  2XRC A;  3CXL A;  3OXG A;  4FKD A;  2SGQ I;  5HI7 A;  1XBT A;  1OMT A;  3BJI A;  4UXJ A;  4UXI A;  1KBF A;  2N17 A;  1W4R A;  2ARP F;  2KCX A;  1TBQ R;  2ODD A;  1M8C A;  2OD1 A;  1UUC A;  3SGB I;  1OVO A;  3OXL A;  3VDU A;  4SGB I;  2LUY A;  1SGE I;  1TGS I;  1DS2 I;  1PTQ A;  2JZM A;  2BUS A;  2L8E A;  2N1A B;  1KBE A;  2GKV A;  2OVO A;  3UGD A;  1CT0 I;  5FUW A;  3SEK C;  3VE5 A;  1FAR A;  1Y1B A;  2JW6 A;  1IY5 A;  3UEJ A;  1BMO A;  2QQC A;  1DS3 I;  3UFF A;  2VRW B;  2QQ0 A;  1BUS A;  1Z7K B;  3KY9 A;  1IW4 A;  1TBR R;  3UGL A;  1HJA I;  2J9R A;  1R0R I;  2P6A C;  3D00 A;  3QWP A;  3TJQ A;  1N13 A;  4HGU A;  1V1H A;  1OYV I;  2JYY A;  1OMU A;  3B4V C;  3FC3 A;  4GI3 C;  1M8B A;  2J87 A;  2NU1 I;  5EX3 A;  1PPF I;  1UVG A;  2A20 A;  2GKR I;  2QQE A;  2KMO A;  5HQ8 A;  1Y8F A;  1TIH A;  2SGD I;  5EX0 A;  3MEK A;  4E1R A;  1CSO I;  2JXD A;  1SGN I;  1TBO A;  2KMR A;  2B8T A;  1PCE A;  2M5X A;  2ELI A;  4B6D A;  4A24 A;  1SGR I;  1IY6 A;  2FNF X;  2V53 A;  1FYB A;  2NU3 I;  1CGJ I;  1NUB A;  3UEY A;  1U5K A;  1RFH A;  2KMQ A;  3RU0 A;  1SGP I;  4L9M A;  2UZ3 A;  3OL0 A;  2NU0 I;  2ROW A;  2NU2 I;  1TUR A;  1LR9 A;  2V1C C;  3SGQ I;  3PDN A;  2V1C A;  1CT4 I;  2DB6 A;  1R79 A;  1CT2 I;  3E59 A;  1TUS A;  1UVF A;  1FAQ A;  3GOX A;  2L7X A;  2NU4 I;  5DAE A;  5FUY A;  3UGI A;  2WVJ A;  4E1P A;  2QQD A;  2YUU A;  1TOT A;  2ENZ A;  2GKT I;  2ORW A;  1H0Z A;  2JA1 A;  1PJU A;  2ORV A;  1MT1 A;  1V1I A;  1CHO I;  2B0U C;  2ENN A;  2ERW A;  2N52 A;  2YQP A;  2SGF I;  1X74 A;  2DIP A;  1KMA A;  1SGY I;  1HDL A;  2E73 A;  2E5R A;  3OXF A;  5CCL A;  2LEO A;  2F3C I;  1TBN A;  3HH2 C;  3QTL D;  2W0T A;  5FUX A;  1SGD I;  1Y1C A;  1LR7 A;  1W3S A;  4UXH A;  5CCM A;  5JHW C;  2GVI A;  1HPT A;  2CJS C;  2SGE I;  1LR8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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