1FHWA

Structure of the pleckstrin homology domain from grp1 in complex with inositol(1,3,4,5,6)pentakisphosphate
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
122
structure length
122
Chain Sequence
PDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
pubmed doi rcsb
molecule keywords GUANINE NUCLEOTIDE EXCHANGE FACTOR AND INTEGRIN BINDING PROT
molecule tags Signaling protein
source organism Mus musculus
total genus 26
structure length 122
sequence length 122
chains with identical sequence B
ec nomenclature
pdb deposition date 2000-08-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1fhwA00
4EKUA 1X11A 4A6FB 5JP4A 1U5DA 2CAYA 1QC6A 5DHFB 4YONA 2HE7A 1UNPA 2AEHA 2YS5A 1IRSA 1V88A 4BBKA 1GC7A 4IOYX 3SV1A 4DBBA 2KGXB 3BINA 4P7IA 4ZRIA 4WJ7A 2D9WA 2DHKA 4K2OA 2XQNM 1X1GA 4K81A 1FHOA 1FGZA 2DKQA 2NMBA 1WGUA 4GPTB 4MT7A 5JHGA 1KZGA 5CLQB 2EMSA 1WI1A 2BCJA 2R09A 3TCAA 2D10A 4HB0B 4DX90 2FJLA 1OY2A 2LOZA 4WVFB 1FHXA 2P8VA 2YS3A 2ADZA 5DHAB 1ZC3B 2YS1A 4Z2NA 2CY4A 2DX1A 2GCJA 1N3HA 1K5DB 1NI2A 2E2XA 2EJ8A 1I2HA 4CHMA 1UEFA 1X05A 3ODXA 1V5MA 4C0AA 4A6HA 1TXDA 4CHJA 3CIKA 2AL6A 4L6EA 3V5WA 3D8FA 2I5CA 2D11A 1X1FA 1P5TA 2YT0A 2DKPA 5LONB 2VRWB 1BWNA 2I1KA 3PVUA 2OQBA 4PNKA 2J0KA 2ROVA 1Y5OA 1ZM0A 2J0MA 1E5WA 4XWXA 2Z0OA 5JHHA 2GCLA 4GXBA 1V89A 1AQCA 1W1DA 5FI1A 1EVHA 1GC6A 3RCPA 3GYPA 3CXBB 2P0HA 4ZRKA 1U5FA 2R0DA 5DI9B 4F7HA 3ULCA 2RVBB 1DDMA 2G35A 1MKEA 3QWMA 3P7ZA 3FSSA 4H8SA 2DX5A 2UZRA 1ZC4B 1U5GA 3PZDA 2RNRB 4EJNA 4WSFA 3KZ1A 5KCVA 1FOEA 1U29A 1J19A 1XD4A 3ODWA 3P6AA 5C5BA 2QKMA 1ISNA 2COCA 3O96A 5C16A 2OTXA 2P0FA 1I7AA 1NTVA 4GN1A 2EC1A 3PG7A 1B55A 2DFKA 2DLWA 4KHOA 1P6SA 1PLSA 2YVCA 1FAOA 3A8PA 4HB4B 2L1CA 5EFXA 1UNQA 2J0JA 4HAVB 3MDBC 1EAZA 2MKRA 1GG3A 3VOQA 2H7DA 4MY6A 5D27A 1WJMA 1RJ2A 3AU5A 3PVWA 2H7EA 2J59M 1TQZA 2RLOA 2N0YA 2KUPA 2MFQA 3KRWA 5C6RA 5D3WA 1WGQA 3KY9A 1TJ6A 3SYXA 3U8ZA 5JLJB 4Y94A 3PEGA 3PP2A 4K2PA 3HQCA 2Y7BA 3D8EA 1Y19B 4HAZB 4HHVA 3TFMA 2Y8FA 1LB1A 3VIAA 5J3YA 2QKLA 4DXAB 1WG7A 2YRYA 3AJ4A 3ZDTA 4KVGB 3UZTA 4Z2MB 1BAKA 2RSGA 3WYFB 4HDOA 4A5KA 3F5RA 1KI1B 1MK9B 1DROA 3IVFA 1SHCA 2I1JA 2N23A 5D3VA 5C5BB 2DYNA 4K17A 4ZRJA 3AU4A 3DXDA 3DXEA 4TKNA 2D2QA 2W2XD 1X86A 1NU2A 3N7CA 4PQ0A 1LW3A 4A6KA 1XCGA 2KCJA 3SUZA 2W2WA 1FHWA 2X18A 3GYOA 5KQ4A 2UVMA 1EGXA 1XX0A 3LJUX 1WVHA 3MPXA 5FI0A 3G9WA 1PFJA 1U5EA 3D8DA 5CLLB 2CRFA 2MWNB 2DN6A 3KRXA 1MIZB 4F7GA 2ZPYA 1DDWA 1V61A 3ZVRA 5L81A 1DDVA 4NY0A 2Y8GA 1OMWA 1P3RA 2W2XC 4DX8A 4KAXB 5LOPB 2COAA 5DH9B 4IFSA 2RGNB 2CODA 2COFA 2GJYA 5DIFB 3DXCA 1EF1A 3U7DA 1ZVRA 2IFSA 1DBHA 1SGHA 3NSUA 4MK0A 4HB2B 2NZ8B 2Z0PA 2LG1A 3SO6A 4YL8A 4KHAA 1BTKA 1DYNA 2RUKB 1H4RA 2LOXA 1U27A 2K00A 5HE0A 3ULBA 2L2IA 2UZSA 2Z0QA 5HE1A 2I5FA 1QQGA 1UPQA 2YSZA 4GZUA 4HB3B 2M14A 3A98B 2ROZB 1OQNA 5C79A 3M1IB 1XR0B 3WA0A 5J3TA 1K5GB 1V5PA 2YF0A 3BJIA 2VKIA 4NSWA 2D9YA 2DYQA 2D4QA 3QBVB 1BTNA 4GMVA 2V76A 4HAXB 3F0WA 5HE3A 1W1HA 1M7EA 1ZSQA 2K2UA 3ODOA 2DA0A 2JP2A 1XKEA 2LYDA 5J3QA 3OANA 4HAYB 5GOWB 1M7RA 2LULA 5HE2A 4F7UP 2Q13A 2M38A 4A6FA 1FGYA 4IAPA 3TO1A 3PSCA 2D9VA 1J0WA 1Q67A 1UPRA 1WJ1A 2HTHB 3PVLA 1H10A 2D9ZA 2EMTA 3T06A 1W1GA 1UNRA 1V5UA 3A8QA 1AWEA 4KHBB 1MAIA 1NTYA 3FM8C 3HK0A 4HATB 2LKOA 3HW2B 2GS0A 1KZ7A 1PMSA 4B6HA 3KSYA 2CY5A 4HDQA 5D3YA 4CYEA 3ML4A 2ELBA 3TVVA 1XODA 2P0DA 3SNHA 1MK7B 1MPHA 3X23A 2IYBA 2PZ1A 1FB8A 3TW1A 2DHJA 2ELAA 4TYZA 2DTCA 4D0NB 2VSZA 1U2BA 2D9XA 5D3XA 2MDXA 2YT1A 3QIJA 4EMOA 4HAUB 3FEHA 4HAWB 2DHIA 5KQ1A 1Z87A 1RRPB 2K2JA 4GMXB 1MIXA
chains in the Genus database with same CATH superfamily
4EKUA 1X11A 4A6FB 5JP4A 1U5DA 5M4YB 2CAYA 1QC6A 5DHFB 4YONA 2HE7A 1UNPA 2AEHA 2YS5A 4QXAB 1IRSA 1V88A 4BBKA 1GC7A 4IOYX 3SV1A 4DBBA 2KGXB 3BINA 4P7IA 4ZRIA 4WJ7A 2D9WA 2DHKA 4K2OA 2XQNM 1X1GA 4GOUA 4K81A 1FGZA 1FHOA 2DKQA 2NMBA 1WGUA 2Z13A 4GPTB 4MT7A 5JHGA 1KZGA 5CLQB 2EMSA 1WI1A 2BCJA 2R09A 3TCAA 2D10A 4HB0B 4DX90 2FJLA 1OY2A 2LOZA 4WVFB 1FHXA 2P8VA 2YS3A 2ADZA 5DHAB 1ZC3B 2YS1A 4Z2NA 2CY4A 2DX1A 2GCJA 1N3HA 1K5DB 1NI2A 2E2XA 2EJ8A 1I2HA 2FJUB 2KUQA 4CHMA 1UEFA 1X05A 3ODXA 1V5MA 4C0AA 4A6HA 2K8EA 1TXDA 4CHJA 3CIKA 2AL6A 4L6EA 3V5WA 3D8FA 2I5CA 2D11A 1X1FA 1P5TA 2YT0A 2DKPA 5LONB 2VRWB 1BWNA 2I1KA 3PVUA 2OQBA 3HIEA 4PNKA 2J0KA 2ROVA 5I2MA 2KR0A 1Y5OA 1ZM0A 2J0MA 1E5WA 4XWXA 4QJ4B 2Z0OA 5JHHA 2GCLA 4GXBA 1V89A 1AQCA 1W1DA 3A58A 2NBVA 5FI1A 1EVHA 1GC6A 3RCPA 3GYPA 3CXBB 2P0HA 4ZRKA 1U5FA 2KIEA 4D6WA 2R0DA 5DI9B 4F7HA 3ULCA 2RVBB 1DDMA 2G35A 1MKEA 3QWMA 3P7ZA 3FSSA 4H8SA 2DX5A 2UZRA 1ZC4B 1U5GA 3PZDA 2RNRB 4EJNA 4WSFA 2KIGA 2RRFA 3KZ1A 5KCVA 1FOEA 1U29A 3FVCA 1J19A 1XD4A 3ODWA 3P6AA 5C5BA 2QKMA 1ISNA 2COCA 3O96A 5C16A 2OTXA 2P0FA 1I7AA 1NTVA 4GN1A 3DCXA 2EC1A 3PG7A 1B55A 2DFKA 2DLWA 4KHOA 1P6SA 1PLSA 2YVCA 1FAOA 3A8PA 4HB4B 2L1CA 5EFXA 1UNQA 2J0JA 4HAVB 3MDBC 1EAZA 2MKRA 1GG3A 3VOQA 2H7DA 2R2YA 4OSNA 4MY6A 5D27A 1WJMA 1RJ2A 3AU5A 3PVWA 2H7EA 2J59M 1TQZA 3B77A 2RLOA 2N0YA 2KUPA 2MFQA 3KRWA 5C6RA 5D3WA 1WGQA 3KY9A 1TJ6A 3SYXA 3U8ZA 5JLJB 4Y94A 3PEGA 3PP2A 4K2PA 5LG4B 3HQCA 1MI1A 2Y7BA 3D8EA 1Y19B 4HAZB 4HHVA 3TFMA 2Y8FA 3NW8A 1LB1A 3VIAA 5J3YA 2QKLA 4DXAB 1WG7A 2YRYA 3AJ4A 3ZDTA 4KVGB 3UZTA 4Z2MB 1BAKA 2RSGA 3WYFB 4HDOA 5I2SA 4A5KA 3F5RA 1KI1B 1MK9B 1DROA 3IVFA 2ZKMX 1SHCA 2I1JA 2N23A 5D3VA 5C5BB 4OT1A 2DYNA 4K17A 4ZRJA 3AU4A 3DXDA 3DXEA 4TKNA 2D2QA 2W2XD 1X86A 1NU2A 3N7CA 4PQ0A 2Z4DA 1LW3A 4A6KA 1XCGA 2KCJA 3SUZA 2W2WA 1FHWA 2X18A 3GYOA 5KQ4A 2UVMA 4QJ3B 2GUMA 1EGXA 1XX0A 3LJUX 1WVHA 3MPXA 5FI0A 3G9WA 1PFJA 1U5EA 3D8DA 5CLLB 2CRFA 2MWNB 2DN6A 3KRXA 1MIZB 4F7GA 2ZPYA 1DDWA 1V61A 3ZVRA 5L81A 1DDVA 5IRSA 4NY0A 2Y8GA 1OMWA 1P3RA 2W2XC 4DX8A 4HSIA 4KAXB 3NWAA 5LOPB 2COAA 5DH9B 4IFSA 2RGNB 2K49A 2CODA 2COFA 2GJYA 5DIFB 3HSAA 3DXCA 1EF1A 3U7DA 1ZVRA 2IFSA 1DBHA 1SGHA 3NSUA 4KHBA 4MK0A 4DIXA 4HB2B 2NZ8B 2Z0PA 2LG1A 3SO6A 4YL8A 4KHAA 4GNKB 1BTKA 1DYNA 2RUKB 1H4RA 2LOXA 3NWDA 1U27A 2K00A 5HE0A 3ULBA 2L2IA 2UZSA 2Z0QA 5HE1A 1T77A 1QQGA 2I5FA 1UPQA 2YSZA 4GZUA 4HB3B 2M14A 3A98B 2ROZB 1OQNA 5C79A 3M1IB 1XR0B 3WA0A 3U12A 5J3TA 1K5GB 1V5PA 2YF0A 3BJIA 2VKIA 4NSWA 2D9YA 2DYQA 2D4QA 2Z14A 3QBVB 1BTNA 4GMVA 2V76A 4HAXB 2Z59A 3F0WA 5HE3A 1W1HA 1M7EA 1ZSQA 2K2UA 3ODOA 2DA0A 2JP2A 1XKEA 2LYDA 5J3QA 3OANA 4HAYB 5GOWB 1M7RA 2LULA 2YT2A 3OHMB 5HE2A 4F7UP 2Q13A 2M38A 4A6FA 1FGYA 4IAPA 3TO1A 3PSCA 2D9VA 1J0WA 1Q67A 1UPRA 1ZYIA 3NWFA 1WJ1A 2HTHB 3PVLA 1H10A 2D9ZA 2EMTA 3T06A 1W1GA 1UNRA 1V5UA 3A8QA 1AWEA 4KHBB 1MAIA 1NTYA 3FM8C 3HK0A 4HATB 2LKOA 3HW2B 2GS0A 1KZ7A 1PMSA 4B6HA 3KSYA 2CY5A 4HDQA 5D3YA 4CYEA 3ML4A 2ELBA 3TVVA 1XODA 2P0DA 3SNHA 1MK7B 1MPHA 3X23A 4L1RA 2IYBA 2PZ1A 1FB8A 3TW1A 2DHJA 2ELAA 4TYZA 4CSQA 2DTCA 4D0NB 2VSZA 1U2BA 2D9XA 5D3XA 2MDXA 2YT1A 3QIJA 4EMOA 4QJ5B 4HAUB 3FEHA 4HAWB 2DHIA 5KQ1A 1Z87A 1RRPB 2K2JA 4GMXB 1MIXA
chains in the Genus database with same CATH topology
4EKUA 1X11A 4A6FB 5JP4A 1U5DA 2CAYA 1QC6A 5DHFB 4YONA 2HE7A 1UNPA 2AEHA 2YS5A 1IRSA 1V88A 4BBKA 1GC7A 4IOYX 3SV1A 4DBBA 2KGXB 3BINA 4P7IA 4ZRIA 4WJ7A 2D9WA 2DHKA 4K2OA 2XQNM 1X1GA 4K81A 1FHOA 1FGZA 2DKQA 2NMBA 1WGUA 4GPTB 4MT7A 5JHGA 1KZGA 5CLQB 2EMSA 1WI1A 2BCJA 2R09A 3TCAA 2D10A 4HB0B 4DX90 2FJLA 1OY2A 2LOZA 4WVFB 1FHXA 2P8VA 2YS3A 2ADZA 5DHAB 1ZC3B 2YS1A 4Z2NA 2CY4A 2DX1A 2GCJA 1N3HA 1K5DB 1NI2A 2E2XA 2EJ8A 1I2HA 4CHMA 1UEFA 1X05A 3ODXA 1V5MA 4C0AA 4A6HA 1TXDA 4CHJA 3CIKA 2AL6A 4L6EA 3V5WA 3D8FA 2I5CA 2D11A 1X1FA 1P5TA 2YT0A 2DKPA 5LONB 2VRWB 1BWNA 2I1KA 3PVUA 2OQBA 4PNKA 2J0KA 2ROVA 1Y5OA 1ZM0A 2J0MA 1E5WA 4XWXA 2Z0OA 5JHHA 2GCLA 4GXBA 1V89A 1AQCA 1W1DA 5FI1A 1EVHA 1GC6A 3RCPA 3GYPA 3CXBB 2P0HA 4ZRKA 1U5FA 2R0DA 5DI9B 4F7HA 3ULCA 2RVBB 1DDMA 2G35A 1MKEA 3QWMA 3P7ZA 3FSSA 4H8SA 2DX5A 2UZRA 1ZC4B 1U5GA 3PZDA 2RNRB 4EJNA 4WSFA 3KZ1A 5KCVA 1FOEA 1U29A 1J19A 1XD4A 3ODWA 3P6AA 5C5BA 2QKMA 1ISNA 2COCA 3O96A 5C16A 2OTXA 2P0FA 1I7AA 1NTVA 4GN1A 2EC1A 3PG7A 1B55A 2DFKA 2DLWA 4KHOA 1P6SA 1PLSA 2YVCA 1FAOA 3A8PA 4HB4B 2L1CA 5EFXA 1UNQA 2J0JA 4HAVB 3MDBC 1EAZA 2MKRA 1GG3A 3VOQA 2H7DA 4MY6A 5D27A 1WJMA 1RJ2A 3AU5A 3PVWA 2H7EA 2J59M 1TQZA 2RLOA 2N0YA 2KUPA 2MFQA 3KRWA 5C6RA 5D3WA 1WGQA 3KY9A 1TJ6A 3SYXA 3U8ZA 5JLJB 4Y94A 3PEGA 3PP2A 4K2PA 3HQCA 2Y7BA 3D8EA 1Y19B 4HAZB 4HHVA 3TFMA 2Y8FA 1LB1A 3VIAA 5J3YA 2QKLA 4DXAB 1WG7A 2YRYA 3AJ4A 3ZDTA 4KVGB 3UZTA 4Z2MB 1BAKA 2RSGA 3WYFB 4HDOA 4A5KA 3F5RA 1KI1B 1MK9B 1DROA 3IVFA 1SHCA 2I1JA 2N23A 5D3VA 5C5BB 2DYNA 4K17A 4ZRJA 3AU4A 3DXDA 3DXEA 4TKNA 2D2QA 2W2XD 1X86A 1NU2A 3N7CA 4PQ0A 1LW3A 4A6KA 1XCGA 2KCJA 3SUZA 2W2WA 1FHWA 2X18A 3GYOA 5KQ4A 2UVMA 1EGXA 1XX0A 3LJUX 1WVHA 3MPXA 5FI0A 3G9WA 1PFJA 1U5EA 3D8DA 5CLLB 2CRFA 2MWNB 2DN6A 3KRXA 1MIZB 4F7GA 2ZPYA 1DDWA 1V61A 3ZVRA 5L81A 1DDVA 4NY0A 2Y8GA 1OMWA 1P3RA 2W2XC 4DX8A 4KAXB 5LOPB 2COAA 5DH9B 4IFSA 2RGNB 2CODA 2COFA 2GJYA 5DIFB 3DXCA 1EF1A 3U7DA 1ZVRA 2IFSA 1DBHA 1SGHA 3NSUA 4MK0A 4HB2B 2NZ8B 2Z0PA 2LG1A 3SO6A 4YL8A 4KHAA 1BTKA 1DYNA 2RUKB 1H4RA 2LOXA 1U27A 2K00A 5HE0A 3ULBA 2L2IA 2UZSA 2Z0QA 5HE1A 2I5FA 1QQGA 1UPQA 2YSZA 4GZUA 4HB3B 2M14A 3A98B 2ROZB 1OQNA 5C79A 3M1IB 1XR0B 3WA0A 5J3TA 1K5GB 1V5PA 2YF0A 3BJIA 2VKIA 4NSWA 2D9YA 2DYQA 2D4QA 3QBVB 1BTNA 4GMVA 2V76A 4HAXB 3F0WA 5HE3A 1W1HA 1M7EA 1ZSQA 2K2UA 3ODOA 2DA0A 2JP2A 1XKEA 2LYDA 5J3QA 3OANA 4HAYB 5GOWB 1M7RA 2LULA 5HE2A 4F7UP 2Q13A 2M38A 4A6FA 1FGYA 4IAPA 3TO1A 3PSCA 2D9VA 1J0WA 1Q67A 1UPRA 1WJ1A 2HTHB 3PVLA 1H10A 2D9ZA 2EMTA 3T06A 1W1GA 1UNRA 1V5UA 3A8QA 1AWEA 4KHBB 1MAIA 1NTYA 3FM8C 3HK0A 4HATB 2LKOA 3HW2B 2GS0A 1KZ7A 1PMSA 4B6HA 3KSYA 2CY5A 4HDQA 5D3YA 4CYEA 3ML4A 2ELBA 3TVVA 1XODA 2P0DA 3SNHA 1MK7B 1MPHA 3X23A 2IYBA 2PZ1A 1FB8A 3TW1A 2DHJA 2ELAA 4TYZA 2DTCA 4D0NB 2VSZA 1U2BA 2D9XA 5D3XA 2MDXA 2YT1A 3QIJA 4EMOA 4HAUB 3FEHA 4HAWB 2DHIA 5KQ1A 1Z87A 1RRPB 2K2JA 4GMXB 1MIXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EKU A;  1X11 A;  4A6F B;  5JP4 A;  1U5D A;  2CAY A;  1QC6 A;  5DHF B;  4YON A;  2HE7 A;  1UNP A;  2AEH A;  2YS5 A;  1IRS A;  1V88 A;  4BBK A;  1GC7 A;  4IOY X;  3SV1 A;  4DBB A;  2KGX B;  3BIN A;  4P7I A;  4ZRI A;  4WJ7 A;  2D9W A;  2DHK A;  4K2O A;  2XQN M;  1X1G A;  4K81 A;  1FHO A;  1FGZ A;  2DKQ A;  2NMB A;  1WGU A;  4GPT B;  4MT7 A;  5JHG A;  1KZG A;  5CLQ B;  2EMS A;  1WI1 A;  2BCJ A;  2R09 A;  3TCA A;  2D10 A;  4HB0 B;  4DX9 0;  2FJL A;  1OY2 A;  2LOZ A;  4WVF B;  1FHX A;  2P8V A;  2YS3 A;  2ADZ A;  5DHA B;  1ZC3 B;  2YS1 A;  4Z2N A;  2CY4 A;  2DX1 A;  2GCJ A;  1N3H A;  1K5D B;  1NI2 A;  2E2X A;  2EJ8 A;  1I2H A;  4CHM A;  1UEF A;  1X05 A;  3ODX A;  1V5M A;  4C0A A;  4A6H A;  1TXD A;  4CHJ A;  3CIK A;  2AL6 A;  4L6E A;  3V5W A;  3D8F A;  2I5C A;  2D11 A;  1X1F A;  1P5T A;  2YT0 A;  2DKP A;  5LON B;  2VRW B;  1BWN A;  2I1K A;  3PVU A;  2OQB A;  4PNK A;  2J0K A;  2ROV A;  1Y5O A;  1ZM0 A;  2J0M A;  1E5W A;  4XWX A;  2Z0O A;  5JHH A;  2GCL A;  4GXB A;  1V89 A;  1AQC A;  1W1D A;  5FI1 A;  1EVH A;  1GC6 A;  3RCP A;  3GYP A;  3CXB B;  2P0H A;  4ZRK A;  1U5F A;  2R0D A;  5DI9 B;  4F7H A;  3ULC A;  2RVB B;  1DDM A;  2G35 A;  1MKE A;  3QWM A;  3P7Z A;  3FSS A;  4H8S A;  2DX5 A;  2UZR A;  1ZC4 B;  1U5G A;  3PZD A;  2RNR B;  4EJN A;  4WSF A;  3KZ1 A;  5KCV A;  1FOE A;  1U29 A;  1J19 A;  1XD4 A;  3ODW A;  3P6A A;  5C5B A;  2QKM A;  1ISN A;  2COC A;  3O96 A;  5C16 A;  2OTX A;  2P0F A;  1I7A A;  1NTV A;  4GN1 A;  2EC1 A;  3PG7 A;  1B55 A;  2DFK A;  2DLW A;  4KHO A;  1P6S A;  1PLS A;  2YVC A;  1FAO A;  3A8P A;  4HB4 B;  2L1C A;  5EFX A;  1UNQ A;  2J0J A;  4HAV B;  3MDB C;  1EAZ A;  2MKR A;  1GG3 A;  3VOQ A;  2H7D A;  4MY6 A;  5D27 A;  1WJM A;  1RJ2 A;  3AU5 A;  3PVW A;  2H7E A;  2J59 M;  1TQZ A;  2RLO A;  2N0Y A;  2KUP A;  2MFQ A;  3KRW A;  5C6R A;  5D3W A;  1WGQ A;  3KY9 A;  1TJ6 A;  3SYX A;  3U8Z A;  5JLJ B;  4Y94 A;  3PEG A;  3PP2 A;  4K2P A;  3HQC A;  2Y7B A;  3D8E A;  1Y19 B;  4HAZ B;  4HHV A;  3TFM A;  2Y8F A;  1LB1 A;  3VIA A;  5J3Y A;  2QKL A;  4DXA B;  1WG7 A;  2YRY A;  3AJ4 A;  3ZDT A;  4KVG B;  3UZT A;  4Z2M B;  1BAK A;  2RSG A;  3WYF B;  4HDO A;  4A5K A;  3F5R A;  1KI1 B;  1MK9 B;  1DRO A;  3IVF A;  1SHC A;  2I1J A;  2N23 A;  5D3V A;  5C5B B;  2DYN A;  4K17 A;  4ZRJ A;  3AU4 A;  3DXD A;  3DXE A;  4TKN A;  2D2Q A;  2W2X D;  1X86 A;  1NU2 A;  3N7C A;  4PQ0 A;  1LW3 A;  4A6K A;  1XCG A;  2KCJ A;  3SUZ A;  2W2W A;  1FHW A;  2X18 A;  3GYO A;  5KQ4 A;  2UVM A;  1EGX A;  1XX0 A;  3LJU X;  1WVH A;  3MPX A;  5FI0 A;  3G9W A;  1PFJ A;  1U5E A;  3D8D A;  5CLL B;  2CRF A;  2MWN B;  2DN6 A;  3KRX A;  1MIZ B;  4F7G A;  2ZPY A;  1DDW A;  1V61 A;  3ZVR A;  5L81 A;  1DDV A;  4NY0 A;  2Y8G A;  1OMW A;  1P3R A;  2W2X C;  4DX8 A;  4KAX B;  5LOP B;  2COA A;  5DH9 B;  4IFS A;  2RGN B;  2COD A;  2COF A;  2GJY A;  5DIF B;  3DXC A;  1EF1 A;  3U7D A;  1ZVR A;  2IFS A;  1DBH A;  1SGH A;  3NSU A;  4MK0 A;  4HB2 B;  2NZ8 B;  2Z0P A;  2LG1 A;  3SO6 A;  4YL8 A;  4KHA A;  1BTK A;  1DYN A;  2RUK B;  1H4R A;  2LOX A;  1U27 A;  2K00 A;  5HE0 A;  3ULB A;  2L2I A;  2UZS A;  2Z0Q A;  5HE1 A;  2I5F A;  1QQG A;  1UPQ A;  2YSZ A;  4GZU A;  4HB3 B;  2M14 A;  3A98 B;  2ROZ B;  1OQN A;  5C79 A;  3M1I B;  1XR0 B;  3WA0 A;  5J3T A;  1K5G B;  1V5P A;  2YF0 A;  3BJI A;  2VKI A;  4NSW A;  2D9Y A;  2DYQ A;  2D4Q A;  3QBV B;  1BTN A;  4GMV A;  2V76 A;  4HAX B;  3F0W A;  5HE3 A;  1W1H A;  1M7E A;  1ZSQ A;  2K2U A;  3ODO A;  2DA0 A;  2JP2 A;  1XKE A;  2LYD A;  5J3Q A;  3OAN A;  4HAY B;  5GOW B;  1M7R A;  2LUL A;  5HE2 A;  4F7U P;  2Q13 A;  2M38 A;  4A6F A;  1FGY A;  4IAP A;  3TO1 A;  3PSC A;  2D9V A;  1J0W A;  1Q67 A;  1UPR A;  1WJ1 A;  2HTH B;  3PVL A;  1H10 A;  2D9Z A;  2EMT A;  3T06 A;  1W1G A;  1UNR A;  1V5U A;  3A8Q A;  1AWE A;  4KHB B;  1MAI A;  1NTY A;  3FM8 C;  3HK0 A;  4HAT B;  2LKO A;  3HW2 B;  2GS0 A;  1KZ7 A;  1PMS A;  4B6H A;  3KSY A;  2CY5 A;  4HDQ A;  5D3Y A;  4CYE A;  3ML4 A;  2ELB A;  3TVV A;  1XOD A;  2P0D A;  3SNH A;  1MK7 B;  1MPH A;  3X23 A;  2IYB A;  2PZ1 A;  1FB8 A;  3TW1 A;  2DHJ A;  2ELA A;  4TYZ A;  2DTC A;  4D0N B;  2VSZ A;  1U2B A;  2D9X A;  5D3X A;  2MDX A;  2YT1 A;  3QIJ A;  4EMO A;  4HAU B;  3FEH A;  4HAW B;  2DHI A;  5KQ1 A;  1Z87 A;  1RRP B;  2K2J A;  4GMX B;  1MIX A; 
#chains in the Genus database with same CATH topology
 4EKU A;  1X11 A;  4A6F B;  5JP4 A;  1U5D A;  5M4Y B;  2CAY A;  1QC6 A;  5DHF B;  4YON A;  2HE7 A;  1UNP A;  2AEH A;  2YS5 A;  4QXA B;  1IRS A;  1V88 A;  4BBK A;  1GC7 A;  4IOY X;  3SV1 A;  4DBB A;  2KGX B;  3BIN A;  4P7I A;  4ZRI A;  4WJ7 A;  2D9W A;  2DHK A;  4K2O A;  2XQN M;  1X1G A;  4GOU A;  4K81 A;  1FGZ A;  1FHO A;  2DKQ A;  2NMB A;  1WGU A;  2Z13 A;  4GPT B;  4MT7 A;  5JHG A;  1KZG A;  5CLQ B;  2EMS A;  1WI1 A;  2BCJ A;  2R09 A;  3TCA A;  2D10 A;  4HB0 B;  4DX9 0;  2FJL A;  1OY2 A;  2LOZ A;  4WVF B;  1FHX A;  2P8V A;  2YS3 A;  2ADZ A;  5DHA B;  1ZC3 B;  2YS1 A;  4Z2N A;  2CY4 A;  2DX1 A;  2GCJ A;  1N3H A;  1K5D B;  1NI2 A;  2E2X A;  2EJ8 A;  1I2H A;  2FJU B;  2KUQ A;  4CHM A;  1UEF A;  1X05 A;  3ODX A;  1V5M A;  4C0A A;  4A6H A;  2K8E A;  1TXD A;  4CHJ A;  3CIK A;  2AL6 A;  4L6E A;  3V5W A;  3D8F A;  2I5C A;  2D11 A;  1X1F A;  1P5T A;  2YT0 A;  2DKP A;  5LON B;  2VRW B;  1BWN A;  2I1K A;  3PVU A;  2OQB A;  3HIE A;  4PNK A;  2J0K A;  2ROV A;  5I2M A;  2KR0 A;  1Y5O A;  1ZM0 A;  2J0M A;  1E5W A;  4XWX A;  4QJ4 B;  2Z0O A;  5JHH A;  2GCL A;  4GXB A;  1V89 A;  1AQC A;  1W1D A;  3A58 A;  2NBV A;  5FI1 A;  1EVH A;  1GC6 A;  3RCP A;  3GYP A;  3CXB B;  2P0H A;  4ZRK A;  1U5F A;  2KIE A;  4D6W A;  2R0D A;  5DI9 B;  4F7H A;  3ULC A;  2RVB B;  1DDM A;  2G35 A;  1MKE A;  3QWM A;  3P7Z A;  3FSS A;  4H8S A;  2DX5 A;  2UZR A;  1ZC4 B;  1U5G A;  3PZD A;  2RNR B;  4EJN A;  4WSF A;  2KIG A;  2RRF A;  3KZ1 A;  5KCV A;  1FOE A;  1U29 A;  3FVC A;  1J19 A;  1XD4 A;  3ODW A;  3P6A A;  5C5B A;  2QKM A;  1ISN A;  2COC A;  3O96 A;  5C16 A;  2OTX A;  2P0F A;  1I7A A;  1NTV A;  4GN1 A;  3DCX A;  2EC1 A;  3PG7 A;  1B55 A;  2DFK A;  2DLW A;  4KHO A;  1P6S A;  1PLS A;  2YVC A;  1FAO A;  3A8P A;  4HB4 B;  2L1C A;  5EFX A;  1UNQ A;  2J0J A;  4HAV B;  3MDB C;  1EAZ A;  2MKR A;  1GG3 A;  3VOQ A;  2H7D A;  2R2Y A;  4OSN A;  4MY6 A;  5D27 A;  1WJM A;  1RJ2 A;  3AU5 A;  3PVW A;  2H7E A;  2J59 M;  1TQZ A;  3B77 A;  2RLO A;  2N0Y A;  2KUP A;  2MFQ A;  3KRW A;  5C6R A;  5D3W A;  1WGQ A;  3KY9 A;  1TJ6 A;  3SYX A;  3U8Z A;  5JLJ B;  4Y94 A;  3PEG A;  3PP2 A;  4K2P A;  5LG4 B;  3HQC A;  1MI1 A;  2Y7B A;  3D8E A;  1Y19 B;  4HAZ B;  4HHV A;  3TFM A;  2Y8F A;  3NW8 A;  1LB1 A;  3VIA A;  5J3Y A;  2QKL A;  4DXA B;  1WG7 A;  2YRY A;  3AJ4 A;  3ZDT A;  4KVG B;  3UZT A;  4Z2M B;  1BAK A;  2RSG A;  3WYF B;  4HDO A;  5I2S A;  4A5K A;  3F5R A;  1KI1 B;  1MK9 B;  1DRO A;  3IVF A;  2ZKM X;  1SHC A;  2I1J A;  2N23 A;  5D3V A;  5C5B B;  4OT1 A;  2DYN A;  4K17 A;  4ZRJ A;  3AU4 A;  3DXD A;  3DXE A;  4TKN A;  2D2Q A;  2W2X D;  1X86 A;  1NU2 A;  3N7C A;  4PQ0 A;  2Z4D A;  1LW3 A;  4A6K A;  1XCG A;  2KCJ A;  3SUZ A;  2W2W A;  1FHW A;  2X18 A;  3GYO A;  5KQ4 A;  2UVM A;  4QJ3 B;  2GUM A;  1EGX A;  1XX0 A;  3LJU X;  1WVH A;  3MPX A;  5FI0 A;  3G9W A;  1PFJ A;  1U5E A;  3D8D A;  5CLL B;  2CRF A;  2MWN B;  2DN6 A;  3KRX A;  1MIZ B;  4F7G A;  2ZPY A;  1DDW A;  1V61 A;  3ZVR A;  5L81 A;  1DDV A;  5IRS A;  4NY0 A;  2Y8G A;  1OMW A;  1P3R A;  2W2X C;  4DX8 A;  4HSI A;  4KAX B;  3NWA A;  5LOP B;  2COA A;  5DH9 B;  4IFS A;  2RGN B;  2K49 A;  2COD A;  2COF A;  2GJY A;  5DIF B;  3HSA A;  3DXC A;  1EF1 A;  3U7D A;  1ZVR A;  2IFS A;  1DBH A;  1SGH A;  3NSU A;  4KHB A;  4MK0 A;  4DIX A;  4HB2 B;  2NZ8 B;  2Z0P A;  2LG1 A;  3SO6 A;  4YL8 A;  4KHA A;  4GNK B;  1BTK A;  1DYN A;  2RUK B;  1H4R A;  2LOX A;  3NWD A;  1U27 A;  2K00 A;  5HE0 A;  3ULB A;  2L2I A;  2UZS A;  2Z0Q A;  5HE1 A;  1T77 A;  1QQG A;  2I5F A;  1UPQ A;  2YSZ A;  4GZU A;  4HB3 B;  2M14 A;  3A98 B;  2ROZ B;  1OQN A;  5C79 A;  3M1I B;  1XR0 B;  3WA0 A;  3U12 A;  5J3T A;  1K5G B;  1V5P A;  2YF0 A;  3BJI A;  2VKI A;  4NSW A;  2D9Y A;  2DYQ A;  2D4Q A;  2Z14 A;  3QBV B;  1BTN A;  4GMV A;  2V76 A;  4HAX B;  2Z59 A;  3F0W A;  5HE3 A;  1W1H A;  1M7E A;  1ZSQ A;  2K2U A;  3ODO A;  2DA0 A;  2JP2 A;  1XKE A;  2LYD A;  5J3Q A;  3OAN A;  4HAY B;  5GOW B;  1M7R A;  2LUL A;  2YT2 A;  3OHM B;  5HE2 A;  4F7U P;  2Q13 A;  2M38 A;  4A6F A;  1FGY A;  4IAP A;  3TO1 A;  3PSC A;  2D9V A;  1J0W A;  1Q67 A;  1UPR A;  1ZYI A;  3NWF A;  1WJ1 A;  2HTH B;  3PVL A;  1H10 A;  2D9Z A;  2EMT A;  3T06 A;  1W1G A;  1UNR A;  1V5U A;  3A8Q A;  1AWE A;  4KHB B;  1MAI A;  1NTY A;  3FM8 C;  3HK0 A;  4HAT B;  2LKO A;  3HW2 B;  2GS0 A;  1KZ7 A;  1PMS A;  4B6H A;  3KSY A;  2CY5 A;  4HDQ A;  5D3Y A;  4CYE A;  3ML4 A;  2ELB A;  3TVV A;  1XOD A;  2P0D A;  3SNH A;  1MK7 B;  1MPH A;  3X23 A;  4L1R A;  2IYB A;  2PZ1 A;  1FB8 A;  3TW1 A;  2DHJ A;  2ELA A;  4TYZ A;  4CSQ A;  2DTC A;  4D0N B;  2VSZ A;  1U2B A;  2D9X A;  5D3X A;  2MDX A;  2YT1 A;  3QIJ A;  4EMO A;  4QJ5 B;  4HAU B;  3FEH A;  4HAW B;  2DHI A;  5KQ1 A;  1Z87 A;  1RRP B;  2K2J A;  4GMX B;  1MIX A; 
#chains in the Genus database with same CATH homology
 4EKU A;  1X11 A;  4A6F B;  5JP4 A;  1U5D A;  2CAY A;  1QC6 A;  5DHF B;  4YON A;  2HE7 A;  1UNP A;  2AEH A;  2YS5 A;  1IRS A;  1V88 A;  4BBK A;  1GC7 A;  4IOY X;  3SV1 A;  4DBB A;  2KGX B;  3BIN A;  4P7I A;  4ZRI A;  4WJ7 A;  2D9W A;  2DHK A;  4K2O A;  2XQN M;  1X1G A;  4K81 A;  1FHO A;  1FGZ A;  2DKQ A;  2NMB A;  1WGU A;  4GPT B;  4MT7 A;  5JHG A;  1KZG A;  5CLQ B;  2EMS A;  1WI1 A;  2BCJ A;  2R09 A;  3TCA A;  2D10 A;  4HB0 B;  4DX9 0;  2FJL A;  1OY2 A;  2LOZ A;  4WVF B;  1FHX A;  2P8V A;  2YS3 A;  2ADZ A;  5DHA B;  1ZC3 B;  2YS1 A;  4Z2N A;  2CY4 A;  2DX1 A;  2GCJ A;  1N3H A;  1K5D B;  1NI2 A;  2E2X A;  2EJ8 A;  1I2H A;  4CHM A;  1UEF A;  1X05 A;  3ODX A;  1V5M A;  4C0A A;  4A6H A;  1TXD A;  4CHJ A;  3CIK A;  2AL6 A;  4L6E A;  3V5W A;  3D8F A;  2I5C A;  2D11 A;  1X1F A;  1P5T A;  2YT0 A;  2DKP A;  5LON B;  2VRW B;  1BWN A;  2I1K A;  3PVU A;  2OQB A;  4PNK A;  2J0K A;  2ROV A;  1Y5O A;  1ZM0 A;  2J0M A;  1E5W A;  4XWX A;  2Z0O A;  5JHH A;  2GCL A;  4GXB A;  1V89 A;  1AQC A;  1W1D A;  5FI1 A;  1EVH A;  1GC6 A;  3RCP A;  3GYP A;  3CXB B;  2P0H A;  4ZRK A;  1U5F A;  2R0D A;  5DI9 B;  4F7H A;  3ULC A;  2RVB B;  1DDM A;  2G35 A;  1MKE A;  3QWM A;  3P7Z A;  3FSS A;  4H8S A;  2DX5 A;  2UZR A;  1ZC4 B;  1U5G A;  3PZD A;  2RNR B;  4EJN A;  4WSF A;  3KZ1 A;  5KCV A;  1FOE A;  1U29 A;  1J19 A;  1XD4 A;  3ODW A;  3P6A A;  5C5B A;  2QKM A;  1ISN A;  2COC A;  3O96 A;  5C16 A;  2OTX A;  2P0F A;  1I7A A;  1NTV A;  4GN1 A;  2EC1 A;  3PG7 A;  1B55 A;  2DFK A;  2DLW A;  4KHO A;  1P6S A;  1PLS A;  2YVC A;  1FAO A;  3A8P A;  4HB4 B;  2L1C A;  5EFX A;  1UNQ A;  2J0J A;  4HAV B;  3MDB C;  1EAZ A;  2MKR A;  1GG3 A;  3VOQ A;  2H7D A;  4MY6 A;  5D27 A;  1WJM A;  1RJ2 A;  3AU5 A;  3PVW A;  2H7E A;  2J59 M;  1TQZ A;  2RLO A;  2N0Y A;  2KUP A;  2MFQ A;  3KRW A;  5C6R A;  5D3W A;  1WGQ A;  3KY9 A;  1TJ6 A;  3SYX A;  3U8Z A;  5JLJ B;  4Y94 A;  3PEG A;  3PP2 A;  4K2P A;  3HQC A;  2Y7B A;  3D8E A;  1Y19 B;  4HAZ B;  4HHV A;  3TFM A;  2Y8F A;  1LB1 A;  3VIA A;  5J3Y A;  2QKL A;  4DXA B;  1WG7 A;  2YRY A;  3AJ4 A;  3ZDT A;  4KVG B;  3UZT A;  4Z2M B;  1BAK A;  2RSG A;  3WYF B;  4HDO A;  4A5K A;  3F5R A;  1KI1 B;  1MK9 B;  1DRO A;  3IVF A;  1SHC A;  2I1J A;  2N23 A;  5D3V A;  5C5B B;  2DYN A;  4K17 A;  4ZRJ A;  3AU4 A;  3DXD A;  3DXE A;  4TKN A;  2D2Q A;  2W2X D;  1X86 A;  1NU2 A;  3N7C A;  4PQ0 A;  1LW3 A;  4A6K A;  1XCG A;  2KCJ A;  3SUZ A;  2W2W A;  1FHW A;  2X18 A;  3GYO A;  5KQ4 A;  2UVM A;  1EGX A;  1XX0 A;  3LJU X;  1WVH A;  3MPX A;  5FI0 A;  3G9W A;  1PFJ A;  1U5E A;  3D8D A;  5CLL B;  2CRF A;  2MWN B;  2DN6 A;  3KRX A;  1MIZ B;  4F7G A;  2ZPY A;  1DDW A;  1V61 A;  3ZVR A;  5L81 A;  1DDV A;  4NY0 A;  2Y8G A;  1OMW A;  1P3R A;  2W2X C;  4DX8 A;  4KAX B;  5LOP B;  2COA A;  5DH9 B;  4IFS A;  2RGN B;  2COD A;  2COF A;  2GJY A;  5DIF B;  3DXC A;  1EF1 A;  3U7D A;  1ZVR A;  2IFS A;  1DBH A;  1SGH A;  3NSU A;  4MK0 A;  4HB2 B;  2NZ8 B;  2Z0P A;  2LG1 A;  3SO6 A;  4YL8 A;  4KHA A;  1BTK A;  1DYN A;  2RUK B;  1H4R A;  2LOX A;  1U27 A;  2K00 A;  5HE0 A;  3ULB A;  2L2I A;  2UZS A;  2Z0Q A;  5HE1 A;  2I5F A;  1QQG A;  1UPQ A;  2YSZ A;  4GZU A;  4HB3 B;  2M14 A;  3A98 B;  2ROZ B;  1OQN A;  5C79 A;  3M1I B;  1XR0 B;  3WA0 A;  5J3T A;  1K5G B;  1V5P A;  2YF0 A;  3BJI A;  2VKI A;  4NSW A;  2D9Y A;  2DYQ A;  2D4Q A;  3QBV B;  1BTN A;  4GMV A;  2V76 A;  4HAX B;  3F0W A;  5HE3 A;  1W1H A;  1M7E A;  1ZSQ A;  2K2U A;  3ODO A;  2DA0 A;  2JP2 A;  1XKE A;  2LYD A;  5J3Q A;  3OAN A;  4HAY B;  5GOW B;  1M7R A;  2LUL A;  5HE2 A;  4F7U P;  2Q13 A;  2M38 A;  4A6F A;  1FGY A;  4IAP A;  3TO1 A;  3PSC A;  2D9V A;  1J0W A;  1Q67 A;  1UPR A;  1WJ1 A;  2HTH B;  3PVL A;  1H10 A;  2D9Z A;  2EMT A;  3T06 A;  1W1G A;  1UNR A;  1V5U A;  3A8Q A;  1AWE A;  4KHB B;  1MAI A;  1NTY A;  3FM8 C;  3HK0 A;  4HAT B;  2LKO A;  3HW2 B;  2GS0 A;  1KZ7 A;  1PMS A;  4B6H A;  3KSY A;  2CY5 A;  4HDQ A;  5D3Y A;  4CYE A;  3ML4 A;  2ELB A;  3TVV A;  1XOD A;  2P0D A;  3SNH A;  1MK7 B;  1MPH A;  3X23 A;  2IYB A;  2PZ1 A;  1FB8 A;  3TW1 A;  2DHJ A;  2ELA A;  4TYZ A;  2DTC A;  4D0N B;  2VSZ A;  1U2B A;  2D9X A;  5D3X A;  2MDX A;  2YT1 A;  3QIJ A;  4EMO A;  4HAU B;  3FEH A;  4HAW B;  2DHI A;  5KQ1 A;  1Z87 A;  1RRP B;  2K2J A;  4GMX B;  1MIX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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