1FJMA

Protein serine/threonine phosphatase-1 (alpha isoform, type 1) complexed with microcystin-lr toxin
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
294
structure length
294
Chain Sequence
b'LNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.
pubmed doi rcsb
molecule keywords PROTEIN SERINE/THREONINE PHOSPHATASE-1 (ALPHA ISOFORM, TYPE
molecule tags Hydrolase/hydrolase inhibitor
total genus 105
structure length 294
sequence length 294
chains with identical sequence B
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 1995-12-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1fjmA00
4H2FA 4M0VA 1II7A 1QHWA 2NXFA 4FCXA 5F3WA 3E7AA 4DHLA 2USHA 4IL1A 4MP0A 2XMOA 3EGHA 3HVQA 1OI8A 2BCDA 5HPEA 3PSNA 4KBPA 1MF8A 2O8GA 2NPPC 2A22A 1IT6A 3JYFA 4XPNA 3RQZA 1WAO1 3H64A 1Z2XA 2R17A 2Z1AA 3ICFA 3QFOA 3H67A 1JK7A 2WDDA 4I5NC 4TUIA 2O8AA 2HYPA 4YKEA 3RL3A 4LU9A 4Q7FA 4ZVZA 3AV0A 3THNA 4V0WA 2KKNA 3P71C 3H60A 5GTUA 1FJMA 5IOHA 3RL4A 2YVTA 3V4YA 1UTEA 3QG5C 3PSOA 5INBA 4I5LC 2WDCA 2AHDA 4UT3A 1XZWA 3GVEA 3H69A 4HD0A 5C1VA 5J28A 1U32A 4H2GA 4UT3B 5DNYA 1OIEA 3ZU0A 4MOVA 4UT2A 3AUZA 3FGAC 2NYLC 1HO5A 1OIDA 1T70A 3IB8A 3H66A 4O5GA 3EGGA 4J6OA 4G9JA 1XM7A 1S95A 2NYMC 4V0XA 5B8IA 1G5BA 2CV9A 1W24A 1Z2WA 2Z06A 4WWLA 3N5UA 2IE4C 3C9FA 3IVDA 4JA9A 5JJTA 4NZVA 2WDEA 2IAEC 2QFRA 3LL8A 3K7WC 5EQVA 4H2BA 3TGHA 4ORCA 2HY1A 3H61A 3H68A 3RL5A 1M63A 1V73A 1UF3A 3E7BA 3IVEA 4O24A 2Z72A 1TCOA 4F0ZA 4DT2A 3KBPA 4IYPC 4JA7A 3QFNA 2HYOA 3K7VC 4ORBA 4ORAA 3THOB 1S8EA 1NNWA 2JOGA 3QFMA 2P6BA 3DSCA 5JPEA 1S70A 4FBWA 4FBQA 4UWQA 4V0VA 4TUGA 3T1IA 3C5WC 4H1SA 4H2IA 1SU1A 2QJCA 1S3MA 4FBKA 1T71A 2BQ8X 1QFCA 1AUIA 2IE3C 2DFJA 3DSDA 2GJUA 4DSYA 1HPUA 3IB7A 4O4KA 3QFKA 1KBPA 4O43A 4LTYA 3H62B 4KKZA 5JPFA 2WDFA 1WARA 2BDXA 4MOYA 1S3NA 4LACC 4B2OA 2ZBMA 4ZX2A 2Q8UA 3DW8C 4OR9A 1S3LA 3ZTVA 3H63A 3CK2A 1HP1A 4H1YP 2QFPA 1USHA
chains in the Genus database with same CATH superfamily
4H2FA 4M0VA 1II7A 1QHWA 2NXFA 4FCXA 5F3WA 3E7AA 4DHLA 2USHA 4IL1A 4MP0A 2XMOA 3EGHA 3HVQA 1OI8A 2BCDA 5HPEA 3PSNA 2ZOAA 4KBPA 1MF8A 2O8GA 2NPPC 2A22A 1IT6A 3JYFA 4XPNA 3RQZA 1WAO1 3H64A 1Z2XA 2R17A 2Z1AA 3ICFA 3QFOA 3H67A 1JK7A 2WDDA 4I5NC 4TUIA 2O8AA 2HYPA 4YKEA 3D03A 3RL3A 4LU9A 4Q7FA 4ZVZA 2ZO9B 3AV0A 3THNA 4V0WA 2KKNA 3P71C 3H60A 5GTUA 2DXNA 1FJMA 5IOHA 3RL4A 2YVTA 3V4YA 1UTEA 3QG5C 3PSOA 5INBA 4I5LC 2WDCA 2AHDA 4UT3A 1XZWA 3GVEA 3H69A 4HD0A 5C1VA 5J28A 1U32A 4H2GA 4UT3B 5DNYA 1OIEA 3ZU0A 4MOVA 4UT2A 3AUZA 3FGAC 2NYLC 1HO5A 1OIDA 1T70A 3IB8A 3H66A 4O5GA 3EGGA 4J6OA 4G9JA 1XM7A 1S95A 2NYMC 4V0XA 5B8IA 1G5BA 2CV9A 1W24A 1Z2WA 2Z06A 4WWLA 3N5UA 2IE4C 3C9FA 3IVDA 4JA9A 5JJTA 4NZVA 2WDEA 2IAEC 2QFRA 3LL8A 3K7WC 5EQVA 3E0JA 4H2BA 3TGHA 4ORCA 2DXLA 2HY1A 3H61A 3H68A 3RL5A 1M63A 1V73A 1UF3A 3E7BA 3IVEA 4O24A 2Z72A 1TCOA 4F0ZA 4DT2A 3KBPA 4IYPC 4JA7A 3QFNA 2HYOA 3K7VC 4ORBA 4ORAA 3THOB 1S8EA 1NNWA 2JOGA 3QFMA 2P6BA 3DSCA 5JPEA 1S70A 4FBWA 4FBQA 4UWQA 4V0VA 4TUGA 3T1IA 3C5WC 4H1SA 4H2IA 1SU1A 2QJCA 1S3MA 4FBKA 1T71A 2BQ8X 1QFCA 1AUIA 2IE3C 2DFJA 3DSDA 2GJUA 4DSYA 1HPUA 3IB7A 4O4KA 3QFKA 1KBPA 4O43A 4LTYA 3H62B 4KKZA 5JPFA 2WDFA 1WARA 2BDXA 4MOYA 1S3NA 4LACC 4B2OA 2ZBMA 4ZX2A 2Q8UA 3DW8C 4OR9A 1S3LA 3ZTVA 2YEQA 3CK2A 3FLOA 1HP1A 3H63A 2QFPA 4H1YP 1USHA
chains in the Genus database with same CATH topology
4H2FA 4M0VA 1II7A 1QHWA 2NXFA 4FCXA 5F3WA 3E7AA 4DHLA 2USHA 4IL1A 4MP0A 2XMOA 3EGHA 3HVQA 1OI8A 2BCDA 5HPEA 3PSNA 2ZOAA 4KBPA 1MF8A 2O8GA 2NPPC 2A22A 1IT6A 3JYFA 4XPNA 3RQZA 1WAO1 3H64A 1Z2XA 2R17A 2Z1AA 3ICFA 3QFOA 3H67A 1JK7A 2WDDA 4I5NC 4TUIA 2O8AA 2HYPA 4YKEA 3D03A 3RL3A 4LU9A 4Q7FA 4ZVZA 2ZO9B 3AV0A 3THNA 4V0WA 2KKNA 3P71C 3H60A 5GTUA 2DXNA 1FJMA 5IOHA 3RL4A 2YVTA 3V4YA 1UTEA 3QG5C 3PSOA 5INBA 4I5LC 2WDCA 2AHDA 4UT3A 1XZWA 3GVEA 3H69A 4HD0A 5C1VA 5J28A 1U32A 4H2GA 4UT3B 5DNYA 1OIEA 3ZU0A 4MOVA 4UT2A 3AUZA 3FGAC 2NYLC 1HO5A 1OIDA 1T70A 3IB8A 3H66A 4O5GA 3EGGA 4J6OA 4G9JA 1XM7A 1S95A 2NYMC 4V0XA 5B8IA 1G5BA 2CV9A 1W24A 1Z2WA 2Z06A 4WWLA 3N5UA 2IE4C 3C9FA 3IVDA 4JA9A 5JJTA 4NZVA 2WDEA 2IAEC 2QFRA 3LL8A 3K7WC 5EQVA 3E0JA 4H2BA 3TGHA 4ORCA 2DXLA 2HY1A 3H61A 3H68A 3RL5A 1M63A 1V73A 1UF3A 3E7BA 3IVEA 4O24A 2Z72A 1TCOA 4F0ZA 4DT2A 3KBPA 4IYPC 4JA7A 3QFNA 2HYOA 3K7VC 4ORBA 4ORAA 3THOB 1S8EA 1NNWA 2JOGA 3QFMA 2P6BA 3DSCA 5JPEA 1S70A 4FBWA 4FBQA 4UWQA 4V0VA 4TUGA 3T1IA 3C5WC 4H1SA 4H2IA 1SU1A 2QJCA 1S3MA 4FBKA 1T71A 2BQ8X 1QFCA 1AUIA 2IE3C 2DFJA 3DSDA 2GJUA 4DSYA 1HPUA 3IB7A 4O4KA 3QFKA 1KBPA 4O43A 4LTYA 3H62B 4KKZA 5JPFA 2WDFA 1WARA 2BDXA 4MOYA 1S3NA 4LACC 4B2OA 2ZBMA 4ZX2A 2Q8UA 3DW8C 4OR9A 1S3LA 3ZTVA 2YEQA 3CK2A 3FLOA 1HP1A 3H63A 2QFPA 4H1YP 1USHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H2F A;  4M0V A;  1II7 A;  1QHW A;  2NXF A;  4FCX A;  5F3W A;  3E7A A;  4DHL A;  2USH A;  4IL1 A;  4MP0 A;  2XMO A;  3EGH A;  3HVQ A;  1OI8 A;  2BCD A;  5HPE A;  3PSN A;  4KBP A;  1MF8 A;  2O8G A;  2NPP C;  2A22 A;  1IT6 A;  3JYF A;  4XPN A;  3RQZ A;  1WAO 1;  3H64 A;  1Z2X A;  2R17 A;  2Z1A A;  3ICF A;  3QFO A;  3H67 A;  1JK7 A;  2WDD A;  4I5N C;  4TUI A;  2O8A A;  2HYP A;  4YKE A;  3RL3 A;  4LU9 A;  4Q7F A;  4ZVZ A;  3AV0 A;  3THN A;  4V0W A;  2KKN A;  3P71 C;  3H60 A;  5GTU A;  1FJM A;  5IOH A;  3RL4 A;  2YVT A;  3V4Y A;  1UTE A;  3QG5 C;  3PSO A;  5INB A;  4I5L C;  2WDC A;  2AHD A;  4UT3 A;  1XZW A;  3GVE A;  3H69 A;  4HD0 A;  5C1V A;  5J28 A;  1U32 A;  4H2G A;  4UT3 B;  5DNY A;  1OIE A;  3ZU0 A;  4MOV A;  4UT2 A;  3AUZ A;  3FGA C;  2NYL C;  1HO5 A;  1OID A;  1T70 A;  3IB8 A;  3H66 A;  4O5G A;  3EGG A;  4J6O A;  4G9J A;  1XM7 A;  1S95 A;  2NYM C;  4V0X A;  5B8I A;  1G5B A;  2CV9 A;  1W24 A;  1Z2W A;  2Z06 A;  4WWL A;  3N5U A;  2IE4 C;  3C9F A;  3IVD A;  4JA9 A;  5JJT A;  4NZV A;  2WDE A;  2IAE C;  2QFR A;  3LL8 A;  3K7W C;  5EQV A;  4H2B A;  3TGH A;  4ORC A;  2HY1 A;  3H61 A;  3H68 A;  3RL5 A;  1M63 A;  1V73 A;  1UF3 A;  3E7B A;  3IVE A;  4O24 A;  2Z72 A;  1TCO A;  4F0Z A;  4DT2 A;  3KBP A;  4IYP C;  4JA7 A;  3QFN A;  2HYO A;  3K7V C;  4ORB A;  4ORA A;  3THO B;  1S8E A;  1NNW A;  2JOG A;  3QFM A;  2P6B A;  3DSC A;  5JPE A;  1S70 A;  4FBW A;  4FBQ A;  4UWQ A;  4V0V A;  4TUG A;  3T1I A;  3C5W C;  4H1S A;  4H2I A;  1SU1 A;  2QJC A;  1S3M A;  4FBK A;  1T71 A;  2BQ8 X;  1QFC A;  1AUI A;  2IE3 C;  2DFJ A;  3DSD A;  2GJU A;  4DSY A;  1HPU A;  3IB7 A;  4O4K A;  3QFK A;  1KBP A;  4O43 A;  4LTY A;  3H62 B;  4KKZ A;  5JPF A;  2WDF A;  1WAR A;  2BDX A;  4MOY A;  1S3N A;  4LAC C;  4B2O A;  2ZBM A;  4ZX2 A;  2Q8U A;  3DW8 C;  4OR9 A;  1S3L A;  3ZTV A;  3H63 A;  3CK2 A;  1HP1 A;  4H1Y P;  2QFP A;  1USH A; 
#chains in the Genus database with same CATH topology
 4H2F A;  4M0V A;  1II7 A;  1QHW A;  2NXF A;  4FCX A;  5F3W A;  3E7A A;  4DHL A;  2USH A;  4IL1 A;  4MP0 A;  2XMO A;  3EGH A;  3HVQ A;  1OI8 A;  2BCD A;  5HPE A;  3PSN A;  2ZOA A;  4KBP A;  1MF8 A;  2O8G A;  2NPP C;  2A22 A;  1IT6 A;  3JYF A;  4XPN A;  3RQZ A;  1WAO 1;  3H64 A;  1Z2X A;  2R17 A;  2Z1A A;  3ICF A;  3QFO A;  3H67 A;  1JK7 A;  2WDD A;  4I5N C;  4TUI A;  2O8A A;  2HYP A;  4YKE A;  3D03 A;  3RL3 A;  4LU9 A;  4Q7F A;  4ZVZ A;  2ZO9 B;  3AV0 A;  3THN A;  4V0W A;  2KKN A;  3P71 C;  3H60 A;  5GTU A;  2DXN A;  1FJM A;  5IOH A;  3RL4 A;  2YVT A;  3V4Y A;  1UTE A;  3QG5 C;  3PSO A;  5INB A;  4I5L C;  2WDC A;  2AHD A;  4UT3 A;  1XZW A;  3GVE A;  3H69 A;  4HD0 A;  5C1V A;  5J28 A;  1U32 A;  4H2G A;  4UT3 B;  5DNY A;  1OIE A;  3ZU0 A;  4MOV A;  4UT2 A;  3AUZ A;  3FGA C;  2NYL C;  1HO5 A;  1OID A;  1T70 A;  3IB8 A;  3H66 A;  4O5G A;  3EGG A;  4J6O A;  4G9J A;  1XM7 A;  1S95 A;  2NYM C;  4V0X A;  5B8I A;  1G5B A;  2CV9 A;  1W24 A;  1Z2W A;  2Z06 A;  4WWL A;  3N5U A;  2IE4 C;  3C9F A;  3IVD A;  4JA9 A;  5JJT A;  4NZV A;  2WDE A;  2IAE C;  2QFR A;  3LL8 A;  3K7W C;  5EQV A;  3E0J A;  4H2B A;  3TGH A;  4ORC A;  2DXL A;  2HY1 A;  3H61 A;  3H68 A;  3RL5 A;  1M63 A;  1V73 A;  1UF3 A;  3E7B A;  3IVE A;  4O24 A;  2Z72 A;  1TCO A;  4F0Z A;  4DT2 A;  3KBP A;  4IYP C;  4JA7 A;  3QFN A;  2HYO A;  3K7V C;  4ORB A;  4ORA A;  3THO B;  1S8E A;  1NNW A;  2JOG A;  3QFM A;  2P6B A;  3DSC A;  5JPE A;  1S70 A;  4FBW A;  4FBQ A;  4UWQ A;  4V0V A;  4TUG A;  3T1I A;  3C5W C;  4H1S A;  4H2I A;  1SU1 A;  2QJC A;  1S3M A;  4FBK A;  1T71 A;  2BQ8 X;  1QFC A;  1AUI A;  2IE3 C;  2DFJ A;  3DSD A;  2GJU A;  4DSY A;  1HPU A;  3IB7 A;  4O4K A;  3QFK A;  1KBP A;  4O43 A;  4LTY A;  3H62 B;  4KKZ A;  5JPF A;  2WDF A;  1WAR A;  2BDX A;  4MOY A;  1S3N A;  4LAC C;  4B2O A;  2ZBM A;  4ZX2 A;  2Q8U A;  3DW8 C;  4OR9 A;  1S3L A;  3ZTV A;  2YEQ A;  3CK2 A;  3FLO A;  1HP1 A;  3H63 A;  2QFP A;  4H1Y P;  1USH A; 
#chains in the Genus database with same CATH homology
 4H2F A;  4M0V A;  1II7 A;  1QHW A;  2NXF A;  4FCX A;  5F3W A;  3E7A A;  4DHL A;  2USH A;  4IL1 A;  4MP0 A;  2XMO A;  3EGH A;  3HVQ A;  1OI8 A;  2BCD A;  5HPE A;  3PSN A;  2ZOA A;  4KBP A;  1MF8 A;  2O8G A;  2NPP C;  2A22 A;  1IT6 A;  3JYF A;  4XPN A;  3RQZ A;  1WAO 1;  3H64 A;  1Z2X A;  2R17 A;  2Z1A A;  3ICF A;  3QFO A;  3H67 A;  1JK7 A;  2WDD A;  4I5N C;  4TUI A;  2O8A A;  2HYP A;  4YKE A;  3D03 A;  3RL3 A;  4LU9 A;  4Q7F A;  4ZVZ A;  2ZO9 B;  3AV0 A;  3THN A;  4V0W A;  2KKN A;  3P71 C;  3H60 A;  5GTU A;  2DXN A;  1FJM A;  5IOH A;  3RL4 A;  2YVT A;  3V4Y A;  1UTE A;  3QG5 C;  3PSO A;  5INB A;  4I5L C;  2WDC A;  2AHD A;  4UT3 A;  1XZW A;  3GVE A;  3H69 A;  4HD0 A;  5C1V A;  5J28 A;  1U32 A;  4H2G A;  4UT3 B;  5DNY A;  1OIE A;  3ZU0 A;  4MOV A;  4UT2 A;  3AUZ A;  3FGA C;  2NYL C;  1HO5 A;  1OID A;  1T70 A;  3IB8 A;  3H66 A;  4O5G A;  3EGG A;  4J6O A;  4G9J A;  1XM7 A;  1S95 A;  2NYM C;  4V0X A;  5B8I A;  1G5B A;  2CV9 A;  1W24 A;  1Z2W A;  2Z06 A;  4WWL A;  3N5U A;  2IE4 C;  3C9F A;  3IVD A;  4JA9 A;  5JJT A;  4NZV A;  2WDE A;  2IAE C;  2QFR A;  3LL8 A;  3K7W C;  5EQV A;  3E0J A;  4H2B A;  3TGH A;  4ORC A;  2DXL A;  2HY1 A;  3H61 A;  3H68 A;  3RL5 A;  1M63 A;  1V73 A;  1UF3 A;  3E7B A;  3IVE A;  4O24 A;  2Z72 A;  1TCO A;  4F0Z A;  4DT2 A;  3KBP A;  4IYP C;  4JA7 A;  3QFN A;  2HYO A;  3K7V C;  4ORB A;  4ORA A;  3THO B;  1S8E A;  1NNW A;  2JOG A;  3QFM A;  2P6B A;  3DSC A;  5JPE A;  1S70 A;  4FBW A;  4FBQ A;  4UWQ A;  4V0V A;  4TUG A;  3T1I A;  3C5W C;  4H1S A;  4H2I A;  1SU1 A;  2QJC A;  1S3M A;  4FBK A;  1T71 A;  2BQ8 X;  1QFC A;  1AUI A;  2IE3 C;  2DFJ A;  3DSD A;  2GJU A;  4DSY A;  1HPU A;  3IB7 A;  4O4K A;  3QFK A;  1KBP A;  4O43 A;  4LTY A;  3H62 B;  4KKZ A;  5JPF A;  2WDF A;  1WAR A;  2BDX A;  4MOY A;  1S3N A;  4LAC C;  4B2O A;  2ZBM A;  4ZX2 A;  2Q8U A;  3DW8 C;  4OR9 A;  1S3L A;  3ZTV A;  2YEQ A;  3CK2 A;  3FLO A;  1HP1 A;  3H63 A;  2QFP A;  4H1Y P;  1USH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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