1FPRA

Crystal structure of the complex formed between the catalytic domain of shp-1 and an in vitro peptide substrate py469 derived from shps-1.
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
284
structure length
284
Chain Sequence
GFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTEIN-TYROSINE PHOSPHATASE 1C
total genus 81
structure length 284
sequence length 284
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1fprA00
4RH9A 5KA9A 4DGPA 1P15A 2FJNA 3V0EA 4QBWA 3N0AA 1XBOA 4JBCA 3EZZA 3QCCA 4NWGA 2F6FA 2CM8A 2PI7A 2F70A 3V0FA 1QZ0A 2F6VA 2AZRA 2YDUA 4ERCA 1T4JA 2ZMMA 2CM3A 4RHGA 4RKKA 1BZCA 4GE2A 2HVLA 1NL9A 2CM2A 1T48A 2F6TA 1A5YA 2QCJA 1NWEA 3EMUA 3OLRA 4QUMA 2HY3A 2I6JA 2DXPA 4R0SA 4OHEA 3F9AA 3V0HA 3ZM0A 2Q47A 1PTUA 3QCNA 1JF7A 3F41A 2PA5A 3AWFA 1D5RA 2GJTA 3S4OA 4GFVA 2F46A 2VEVA 4KYRA 4JMJA 2P6XA 3QCEA 4KYQA 3A5JA 4HRFA 1I57A 2FH7A 1OEMX 4GWFA 1YWFA 5HDEA 2PSZA 2CNEA 2A8BA 4TVVA 3NMEA 2P4DA 2QBPA 1ZCKA 2NV5A 5KA0A 2I3UA 2J17A 1RXDA 2B4SA 2G6ZA 1PXHA 4GE5A 2CFVA 4GRYA 2MBCA 4YAAA 3BM8A 1OEUA 1ZCLA 3AWGA 1PA1A 1WCHA 3QCHA 2OOQA 2H4KA 4RDDA 3BLUA 4Y14A 4IKCA 1Q6JA 3D1QA 1NWLA 3QCJA 1ECVA 3D1OA 3A5KA 3BLTA 1WAXA 1Q6NA 4ZN5A 3QCIA 2QDCA 4QBEA 1ONYA 3EB1A 3S4EA 1OESA 2H4VA 2I6OA 3MOZA 4NYHA 1L8GA 4JMKA 1VHRA 3O4SA 5EHRA 2A3KA 5K9VA 2CMCA 4HJPA 3V0GA 4B04A 4HJQA 5KA2A 4QAHA 2CNGA 4D3PA 2CMAA 3RZ2A 1AAXA 2CM7A 2CNHA 3S3EA 4GE6A 3RO1A 4OHLA 3PS5A 4DGXA 4YR8B 4KI9A 4RI4A 2SHPA 3QCGA 2FJMA 2QCTA 5IBMA 2F6YA 2HB1A 3EAXA 3D42A 1XXVA 1PTYA 4PYHA 1GFYA 4S0GA 5EHPA 1ZC0A 1NZ7A 3H2XA 1G1GA 1G4US 2R0BA 4WU3A 3M4UA 1YN9A 3RGQA 2HC1A 1OEVA 1EENA 2F6WA 1YTWA 5J8RA 1MKPA 3D9CA 4WOHA 4RH5A 5KACA 2Y96A 3V0JA 2OZ5A 1YPTA 2PQ5A 3S3FA 2M3VA 2BZLA 2HNQA 1WRMA 2Q05A 2BIJA 2H4GA 2JJDA 3QKPA 2VEXA 2B3OA 4WU2A 1PTTA 3QCDA 1C87A 3MOWA 1G1HA 3I36A 3BRHA 1L8KA 2B4OA 4MBBA 3ZM3A 2OC3A 1U25A 3GXHA 4ZRTA 1LARA 4Y2EA 3CWEA 1I9SA 2Y2FA 1C83A 2C46A 2CMBA 5MMZB 1G1FA 2I6IA 2J16A 3EU0A 1YGUA 2J16B 5K23A 3O5XA 1G4WR 2GWOA 1SUGA 1YFOA 2CNFA 3I80A 3O4UA 5KA7A 3GXGA 5AWXA 2ESBA 4GRZA 2B4PA 3LJ8A 4R0TA 4GS0A 4OHHA 1JLNA 1QXKA 5K25A 2AHSA 2CNIA 2HC2A 1FPZA 5K9WA 1PTVA 1R6HA 2HNPA 4J51A 1NO6A 5KA3A 3ZV2A 1X24A 5BUGA 1Q6MA 5LXQB 1OEOX 1YZ4A 1C88A 2NLKA 3U96A 2ZN7A 5BX1A 3O3LA 3S3HA 4OHIA 3ZM2A 1GWZA 2VEUA 2WGPA 2B07A 2I4GA 3MMJA 1G7GA 2QEPA 5KAAA 1Q6PA 1U24A 2H04A 1G7FA 2QBRA 2B49A 1Q6TA 2NTAA 4NWFA 3QCFA 4R30A 2BGDA 4JNBA 3F9BA 2I6PA 2BV5A 2F6ZA 2NZ6A 2BGEA 3V0DA 1C84A 2QBSA 3QCMA 5KADA 4BJOA 5KABA 3QKQA 2RF6A 2NT7A 4H34A 5GTJA 1XM2A 3ZMPA 2H03A 3B7OA 1T49A 2CJZA 4D3RA 5KA1A 2I5XA 3QCKA 3SR9A 1V3AA 1LQFA 2VEWA 1KAKA 2GP0A 5BZZA 4ZI4A 2I3RA 4WTYA 1ONZA 4Z6BA 1OHEA 3OMHA 1LYVA 4QUNA 2B4UA 1KAVA 3RGOA 1I9TA 2C7SA 2QDMA 3D1HA 1YGRA 2PT0A 2I75A 2I4EA 2PBNA 2VEYA 3SMEA 2NT2A 2I6MA 2E0TA 3AWEA 4ICZA 1NNYA 1FQ1A 1YTSA 1ZZWA 1RPMA 4H1OA 2HCMA 2I4HA 5I6VA 4BPCA 4OHDA 1XRIA 1C86A 1PH0A 1PYNA 5IBSA 5KA4A 4QAPA 5K24A 5KA8A 3S3KA 1U26A 2QDPA 2OUDA 3D44A 1PA9A 3QCLA 1EEOA 1C85A 1OETA 3CM3A 2HXPA 2I42A 4D3QA 1OHCA 4AZ1A 3I7ZA 2H02A 5K22A 2QBQA 1OHDA 3O4TA 1J4XA 4NX8A 4I8NA 1FPRA 3F81A 4NNDA 2IMGA 1XXPA 1M3GA 2I1YA 4PVGA 5BZXA 2F71A 4RI5A 4GFUA 1BZJA 3ZM1A 1BZHA 5M43A 3V0IA 1Q6SA 2G59A 1YTNA 3ZMQA 1Q1MA 3QCBA 3F99A
chains in the Genus database with same CATH superfamily
4RH9A 5KA9A 4DGPA 1P15A 2FJNA 3V0EA 4QBWA 3N0AA 1XBOA 4JBCA 3EZZA 3QCCA 4NWGA 2F6FA 2CM8A 2PI7A 2F70A 3V0FA 4BUBA 1QZ0A 2F6VA 1J6UA 3ZM6A 2AZRA 2YDUA 4ERCA 1T4JA 2ZMMA 2CM3A 4RHGA 2VTDA 4RKKA 1BZCA 4GE2A 2HVLA 1NL9A 2CM2A 1T48A 2F6TA 1A5YA 2QCJA 1W78A 4CVMA 2JFFA 1NWEA 3EMUA 3OLRA 4QUMA 2HY3A 2I6JA 2DXPA 4R0SA 2VOSA 4UAGA 4OHEA 3F9AA 3V0HA 3ZM0A 2GC6A 2Q47A 1PTUA 3LK7A 3QCNA 1JF7A 3F41A 2PA5A 3AWFA 1D5RA 2GJTA 3S4OA 4GFVA 2F46A 2VEVA 4KYRA 4JMJA 2P6XA 3QCEA 4QF5A 4KYQA 3A5JA 3QCZA 4HRFA 1I57A 2FH7A 1OEMX 3ZM5A 4GWFA 1YWFA 5HDEA 2PSZA 2CNEA 2A8BA 4TVVA 3NMEA 2P4DA 2QBPA 1ZCKA 1GQYA 2NV5A 5KA0A 2I3UA 2J17A 1RXDA 2B4SA 4ZIYA 2G6ZA 1PXHA 4GE5A 2CFVA 4GRYA 2MBCA 4YAAA 3BM8A 1OEUA 2Y67A 1ZCLA 3AWGA 1PA1A 4CVKA 2Y68A 1WCHA 2OOQA 3QCHA 1EEHA 2H4KA 4RDDA 3BLUA 4Y14A 4IKCA 1Q6JA 3D1QA 1NWLA 3QCJA 1ECVA 3D1OA 3A5KA 3BLTA 1WAXA 1Q6NA 4C13A 4ZN5A 3QCIA 2JFHA 1JBWA 2QDCA 4QBEA 1ONYA 3EB1A 2UUOA 3S4EA 1OESA 2H4VA 2I6OA 3MOZA 4NYHA 4CVLA 2Y1OA 1L8GA 4JMKA 1VHRA 3O4SA 5EHRA 2A3KA 5K9VA 2CMCA 4HJPA 3V0GA 4B04A 2VTEA 4HJQA 5KA2A 1W7KA 4QAHA 2CNGA 4D3PA 2CMAA 3RZ2A 1AAXA 2CM7A 2CNHA 3S3EA 4GE6A 3RO1A 2XJAA 4OHLA 3PS5A 4DGXA 4YR8B 4KI9A 4RI4A 2SHPA 3QCGA 2FJMA 2QCTA 5IBMA 4QDIA 2F6YA 1E0DA 2HB1A 3EAXA 3D42A 1XXVA 1PTYA 4PYHA 1GFYA 1E8CA 4S0GA 5EHPA 1ZC0A 1NZ7A 3H2XA 1G1GA 2WTZA 1G4US 2WJPA 2R0BA 4WU3A 3M4UA 1YN9A 3RGQA 2HC1A 1OEVA 1EENA 2F6WA 1YTWA 5J8RA 1MKPA 2Y66A 3D9CA 4WOHA 4BUCA 4RH5A 5KACA 2Y96A 3V0JA 2OZ5A 1YPTA 2PQ5A 3S3FA 2M3VA 2BZLA 2HNQA 1WRMA 2Q05A 2BIJA 2H4GA 3ZL8A 2JJDA 3QKPA 2VEXA 2B3OA 4WU2A 1PTTA 3QCDA 1C87A 3MOWA 1G1HA 3I36A 3BRHA 1L8KA 2B4OA 4MBBA 3ZM3A 2OC3A 2JFGA 1U25A 3GXHA 4ZRTA 2AM2A 1LARA 2XPCA 4Y2EA 2UAGA 3CWEA 1I9SA 2Y2FA 1C83A 2GCAA 2C46A 2CMBA 5MMZB 1G1FA 2I6IA 2J16A 3EU0A 3UAGA 1YGUA 2J16B 1JBVA 5K23A 5A5FA 3O5XA 1G4WR 2GWOA 1SUGA 1YFOA 2CNFA 3I80A 3O4UA 5KA7A 3GXGA 5AWXA 2ESBA 2VORA 4GRZA 2B4PA 3LJ8A 1O5ZA 4R0TA 4GS0A 4OHHA 1JLNA 1QXKA 5K25A 2AHSA 2CNIA 2HC2A 1FPZA 5K9WA 3PYZA 1PTVA 1R6HA 2HNPA 4J51A 1NO6A 5KA3A 3ZV2A 1X24A 3N2AA 5BUGA 1Q6MA 5LXQB 1OEOX 1YZ4A 1C88A 2NLKA 3U96A 2ZN7A 4C12A 5BX1A 3O3LA 2X5OA 3S3HA 4OHIA 3NRSA 3ZM2A 1GWZA 2VEUA 2WGPA 2B07A 2I4GA 3MMJA 2F00A 1G7GA 2QEPA 1P3DA 5KAAA 1Q6PA 1U24A 3MVNA 2H04A 1G7FA 2QBRA 2B49A 1Q6TA 1GQQA 2NTAA 4NWFA 3QCFA 4R30A 2BGDA 4JNBA 2I6PA 3F9BA 2BV5A 1UAGA 2F6ZA 2NZ6A 2BGEA 2UUPA 3V0DA 1C84A 2QBSA 3QCMA 5KADA 4BJOA 5KABA 3QKQA 2RF6A 2NT7A 4H34A 5GTJA 1XM2A 3ZMPA 2H03A 3B7OA 1T49A 2CJZA 4D3RA 5KA1A 2I5XA 3QCKA 2AM1A 3SR9A 1V3AA 1LQFA 2VEWA 4HV4A 1GG4A 1KAKA 2GP0A 5BZZA 4ZI4A 2I3RA 4WTYA 1ONZA 4Z6BA 1OHEA 3OMHA 1LYVA 4QUNA 2B4UA 2GCBA 1KAVA 3RGOA 1I9TA 2C7SA 2QDMA 3D1HA 1P31A 1YGRA 2PT0A 2I75A 2I4EA 2PBNA 2VEYA 3SMEA 2NT2A 2I6MA 2E0TA 3AWEA 4ICZA 1NNYA 1FQ1A 1YTSA 1ZZWA 1RPMA 4H1OA 2HCMA 2I4HA 5I6VA 4BPCA 4OHDA 1XRIA 1C86A 1PH0A 1PYNA 5IBSA 5KA4A 4QAPA 5K24A 5KA8A 3S3KA 1U26A 2QDPA 2OUDA 3D44A 1PA9A 3QCLA 1EEOA 1C85A 1OETA 3CM3A 2HXPA 2I42A 4D3QA 1OHCA 4AZ1A 3I7ZA 2H02A 5K22A 2QBQA 1OHDA 3O4TA 1J4XA 4NX8A 4I8NA 1FPRA 3F81A 4NNDA 2IMGA 2GC5A 1XXPA 1M3GA 2I1YA 4PVGA 5BZXA 2F71A 4RI5A 4GFUA 1BZJA 3HN7A 3ZM1A 1BZHA 5M43A 3V0IA 1Q6SA 5A5EA 2G59A 1FGSA 1YTNA 3ZMQA 1Q1MA 3QCBA 3F99A
chains in the Genus database with same CATH topology
4RH9A 5KA9A 4DGPA 1P15A 2FJNA 3V0EA 4QBWA 3N0AA 1XBOA 4JBCA 3EZZA 3QCCA 4NWGA 2F6FA 2CM8A 2PI7A 2F70A 3V0FA 1QZ0A 2F6VA 2AZRA 2YDUA 4ERCA 1T4JA 2ZMMA 2CM3A 4RHGA 4RKKA 1BZCA 4GE2A 2HVLA 1NL9A 2CM2A 1T48A 2F6TA 1A5YA 2QCJA 1NWEA 3EMUA 3OLRA 4QUMA 2HY3A 2I6JA 2DXPA 4R0SA 4OHEA 3F9AA 3V0HA 3ZM0A 2Q47A 1PTUA 3QCNA 1JF7A 3F41A 2PA5A 3AWFA 1D5RA 2GJTA 3S4OA 4GFVA 2F46A 2VEVA 4KYRA 4JMJA 2P6XA 3QCEA 4KYQA 3A5JA 4HRFA 1I57A 2FH7A 1OEMX 4GWFA 1YWFA 5HDEA 2PSZA 2CNEA 2A8BA 4TVVA 3NMEA 2P4DA 2QBPA 1ZCKA 2NV5A 5KA0A 2I3UA 2J17A 1RXDA 2B4SA 2G6ZA 1PXHA 4GE5A 2CFVA 4GRYA 2MBCA 4YAAA 3BM8A 1OEUA 1ZCLA 3AWGA 1PA1A 1WCHA 3QCHA 2OOQA 2H4KA 4RDDA 3BLUA 4Y14A 4IKCA 1Q6JA 3D1QA 1NWLA 3QCJA 1ECVA 3D1OA 3A5KA 3BLTA 1WAXA 1Q6NA 4ZN5A 3QCIA 2QDCA 4QBEA 1ONYA 3EB1A 3S4EA 1OESA 2H4VA 2I6OA 3MOZA 4NYHA 1L8GA 4JMKA 1VHRA 3O4SA 5EHRA 2A3KA 5K9VA 2CMCA 4HJPA 3V0GA 4B04A 4HJQA 5KA2A 4QAHA 2CNGA 4D3PA 2CMAA 3RZ2A 1AAXA 2CM7A 2CNHA 3S3EA 4GE6A 3RO1A 4OHLA 3PS5A 4DGXA 4YR8B 4KI9A 4RI4A 2SHPA 3QCGA 2FJMA 2QCTA 5IBMA 2F6YA 2HB1A 3EAXA 3D42A 1XXVA 1PTYA 4PYHA 1GFYA 4S0GA 5EHPA 1ZC0A 1NZ7A 3H2XA 1G1GA 1G4US 2R0BA 4WU3A 3M4UA 1YN9A 3RGQA 2HC1A 1OEVA 1EENA 2F6WA 1YTWA 5J8RA 1MKPA 3D9CA 4WOHA 4RH5A 5KACA 2Y96A 3V0JA 2OZ5A 1YPTA 2PQ5A 3S3FA 2M3VA 2BZLA 2HNQA 1WRMA 2Q05A 2BIJA 2H4GA 2JJDA 3QKPA 2VEXA 2B3OA 4WU2A 1PTTA 3QCDA 1C87A 3MOWA 1G1HA 3I36A 3BRHA 1L8KA 2B4OA 4MBBA 3ZM3A 2OC3A 1U25A 3GXHA 4ZRTA 1LARA 4Y2EA 3CWEA 1I9SA 2Y2FA 1C83A 2C46A 2CMBA 5MMZB 1G1FA 2I6IA 2J16A 3EU0A 1YGUA 2J16B 5K23A 3O5XA 1G4WR 2GWOA 1SUGA 1YFOA 2CNFA 3I80A 3O4UA 5KA7A 3GXGA 5AWXA 2ESBA 4GRZA 2B4PA 3LJ8A 4R0TA 4GS0A 4OHHA 1JLNA 1QXKA 5K25A 2AHSA 2CNIA 2HC2A 1FPZA 5K9WA 1PTVA 1R6HA 2HNPA 4J51A 1NO6A 5KA3A 3ZV2A 1X24A 5BUGA 1Q6MA 5LXQB 1OEOX 1YZ4A 1C88A 2NLKA 3U96A 2ZN7A 5BX1A 3O3LA 3S3HA 4OHIA 3ZM2A 1GWZA 2VEUA 2WGPA 2B07A 2I4GA 3MMJA 1G7GA 2QEPA 5KAAA 1Q6PA 1U24A 2H04A 1G7FA 2QBRA 2B49A 1Q6TA 2NTAA 4NWFA 3QCFA 4R30A 2BGDA 4JNBA 3F9BA 2I6PA 2BV5A 2F6ZA 2NZ6A 2BGEA 3V0DA 1C84A 2QBSA 3QCMA 5KADA 4BJOA 5KABA 3QKQA 2RF6A 2NT7A 4H34A 5GTJA 1XM2A 3ZMPA 2H03A 3B7OA 1T49A 2CJZA 4D3RA 5KA1A 2I5XA 3QCKA 3SR9A 1V3AA 1LQFA 2VEWA 1KAKA 2GP0A 5BZZA 4ZI4A 2I3RA 4WTYA 1ONZA 4Z6BA 1OHEA 3OMHA 1LYVA 4QUNA 2B4UA 1KAVA 3RGOA 1I9TA 2C7SA 2QDMA 3D1HA 1YGRA 2PT0A 2I75A 2I4EA 2PBNA 2VEYA 3SMEA 2NT2A 2I6MA 2E0TA 3AWEA 4ICZA 1NNYA 1FQ1A 1YTSA 1ZZWA 1RPMA 4H1OA 2HCMA 2I4HA 5I6VA 4BPCA 4OHDA 1XRIA 1C86A 1PH0A 1PYNA 5IBSA 5KA4A 4QAPA 5K24A 5KA8A 3S3KA 1U26A 2QDPA 2OUDA 3D44A 1PA9A 3QCLA 1EEOA 1C85A 1OETA 3CM3A 2HXPA 2I42A 4D3QA 1OHCA 4AZ1A 3I7ZA 2H02A 5K22A 2QBQA 1OHDA 3O4TA 1J4XA 4NX8A 4I8NA 1FPRA 3F81A 4NNDA 2IMGA 1XXPA 1M3GA 2I1YA 4PVGA 5BZXA 2F71A 4RI5A 4GFUA 1BZJA 3ZM1A 1BZHA 5M43A 3V0IA 1Q6SA 2G59A 1YTNA 3ZMQA 1Q1MA 3QCBA 3F99A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RH9 A;  5KA9 A;  4DGP A;  1P15 A;  2FJN A;  3V0E A;  4QBW A;  3N0A A;  1XBO A;  4JBC A;  3EZZ A;  3QCC A;  4NWG A;  2F6F A;  2CM8 A;  2PI7 A;  2F70 A;  3V0F A;  1QZ0 A;  2F6V A;  2AZR A;  2YDU A;  4ERC A;  1T4J A;  2ZMM A;  2CM3 A;  4RHG A;  4RKK A;  1BZC A;  4GE2 A;  2HVL A;  1NL9 A;  2CM2 A;  1T48 A;  2F6T A;  1A5Y A;  2QCJ A;  1NWE A;  3EMU A;  3OLR A;  4QUM A;  2HY3 A;  2I6J A;  2DXP A;  4R0S A;  4OHE A;  3F9A A;  3V0H A;  3ZM0 A;  2Q47 A;  1PTU A;  3QCN A;  1JF7 A;  3F41 A;  2PA5 A;  3AWF A;  1D5R A;  2GJT A;  3S4O A;  4GFV A;  2F46 A;  2VEV A;  4KYR A;  4JMJ A;  2P6X A;  3QCE A;  4KYQ A;  3A5J A;  4HRF A;  1I57 A;  2FH7 A;  1OEM X;  4GWF A;  1YWF A;  5HDE A;  2PSZ A;  2CNE A;  2A8B A;  4TVV A;  3NME A;  2P4D A;  2QBP A;  1ZCK A;  2NV5 A;  5KA0 A;  2I3U A;  2J17 A;  1RXD A;  2B4S A;  2G6Z A;  1PXH A;  4GE5 A;  2CFV A;  4GRY A;  2MBC A;  4YAA A;  3BM8 A;  1OEU A;  1ZCL A;  3AWG A;  1PA1 A;  1WCH A;  3QCH A;  2OOQ A;  2H4K A;  4RDD A;  3BLU A;  4Y14 A;  4IKC A;  1Q6J A;  3D1Q A;  1NWL A;  3QCJ A;  1ECV A;  3D1O A;  3A5K A;  3BLT A;  1WAX A;  1Q6N A;  4ZN5 A;  3QCI A;  2QDC A;  4QBE A;  1ONY A;  3EB1 A;  3S4E A;  1OES A;  2H4V A;  2I6O A;  3MOZ A;  4NYH A;  1L8G A;  4JMK A;  1VHR A;  3O4S A;  5EHR A;  2A3K A;  5K9V A;  2CMC A;  4HJP A;  3V0G A;  4B04 A;  4HJQ A;  5KA2 A;  4QAH A;  2CNG A;  4D3P A;  2CMA A;  3RZ2 A;  1AAX A;  2CM7 A;  2CNH A;  3S3E A;  4GE6 A;  3RO1 A;  4OHL A;  3PS5 A;  4DGX A;  4YR8 B;  4KI9 A;  4RI4 A;  2SHP A;  3QCG A;  2FJM A;  2QCT A;  5IBM A;  2F6Y A;  2HB1 A;  3EAX A;  3D42 A;  1XXV A;  1PTY A;  4PYH A;  1GFY A;  4S0G A;  5EHP A;  1ZC0 A;  1NZ7 A;  3H2X A;  1G1G A;  1G4U S;  2R0B A;  4WU3 A;  3M4U A;  1YN9 A;  3RGQ A;  2HC1 A;  1OEV A;  1EEN A;  2F6W A;  1YTW A;  5J8R A;  1MKP A;  3D9C A;  4WOH A;  4RH5 A;  5KAC A;  2Y96 A;  3V0J A;  2OZ5 A;  1YPT A;  2PQ5 A;  3S3F A;  2M3V A;  2BZL A;  2HNQ A;  1WRM A;  2Q05 A;  2BIJ A;  2H4G A;  2JJD A;  3QKP A;  2VEX A;  2B3O A;  4WU2 A;  1PTT A;  3QCD A;  1C87 A;  3MOW A;  1G1H A;  3I36 A;  3BRH A;  1L8K A;  2B4O A;  4MBB A;  3ZM3 A;  2OC3 A;  1U25 A;  3GXH A;  4ZRT A;  1LAR A;  4Y2E A;  3CWE A;  1I9S A;  2Y2F A;  1C83 A;  2C46 A;  2CMB A;  5MMZ B;  1G1F A;  2I6I A;  2J16 A;  3EU0 A;  1YGU A;  2J16 B;  5K23 A;  3O5X A;  1G4W R;  2GWO A;  1SUG A;  1YFO A;  2CNF A;  3I80 A;  3O4U A;  5KA7 A;  3GXG A;  5AWX A;  2ESB A;  4GRZ A;  2B4P A;  3LJ8 A;  4R0T A;  4GS0 A;  4OHH A;  1JLN A;  1QXK A;  5K25 A;  2AHS A;  2CNI A;  2HC2 A;  1FPZ A;  5K9W A;  1PTV A;  1R6H A;  2HNP A;  4J51 A;  1NO6 A;  5KA3 A;  3ZV2 A;  1X24 A;  5BUG A;  1Q6M A;  5LXQ B;  1OEO X;  1YZ4 A;  1C88 A;  2NLK A;  3U96 A;  2ZN7 A;  5BX1 A;  3O3L A;  3S3H A;  4OHI A;  3ZM2 A;  1GWZ A;  2VEU A;  2WGP A;  2B07 A;  2I4G A;  3MMJ A;  1G7G A;  2QEP A;  5KAA A;  1Q6P A;  1U24 A;  2H04 A;  1G7F A;  2QBR A;  2B49 A;  1Q6T A;  2NTA A;  4NWF A;  3QCF A;  4R30 A;  2BGD A;  4JNB A;  3F9B A;  2I6P A;  2BV5 A;  2F6Z A;  2NZ6 A;  2BGE A;  3V0D A;  1C84 A;  2QBS A;  3QCM A;  5KAD A;  4BJO A;  5KAB A;  3QKQ A;  2RF6 A;  2NT7 A;  4H34 A;  5GTJ A;  1XM2 A;  3ZMP A;  2H03 A;  3B7O A;  1T49 A;  2CJZ A;  4D3R A;  5KA1 A;  2I5X A;  3QCK A;  3SR9 A;  1V3A A;  1LQF A;  2VEW A;  1KAK A;  2GP0 A;  5BZZ A;  4ZI4 A;  2I3R A;  4WTY A;  1ONZ A;  4Z6B A;  1OHE A;  3OMH A;  1LYV A;  4QUN A;  2B4U A;  1KAV A;  3RGO A;  1I9T A;  2C7S A;  2QDM A;  3D1H A;  1YGR A;  2PT0 A;  2I75 A;  2I4E A;  2PBN A;  2VEY A;  3SME A;  2NT2 A;  2I6M A;  2E0T A;  3AWE A;  4ICZ A;  1NNY A;  1FQ1 A;  1YTS A;  1ZZW A;  1RPM A;  4H1O A;  2HCM A;  2I4H A;  5I6V A;  4BPC A;  4OHD A;  1XRI A;  1C86 A;  1PH0 A;  1PYN A;  5IBS A;  5KA4 A;  4QAP A;  5K24 A;  5KA8 A;  3S3K A;  1U26 A;  2QDP A;  2OUD A;  3D44 A;  1PA9 A;  3QCL A;  1EEO A;  1C85 A;  1OET A;  3CM3 A;  2HXP A;  2I42 A;  4D3Q A;  1OHC A;  4AZ1 A;  3I7Z A;  2H02 A;  5K22 A;  2QBQ A;  1OHD A;  3O4T A;  1J4X A;  4NX8 A;  4I8N A;  1FPR A;  3F81 A;  4NND A;  2IMG A;  1XXP A;  1M3G A;  2I1Y A;  4PVG A;  5BZX A;  2F71 A;  4RI5 A;  4GFU A;  1BZJ A;  3ZM1 A;  1BZH A;  5M43 A;  3V0I A;  1Q6S A;  2G59 A;  1YTN A;  3ZMQ A;  1Q1M A;  3QCB A;  3F99 A; 
#chains in the Genus database with same CATH topology
 4RH9 A;  5KA9 A;  4DGP A;  1P15 A;  2FJN A;  3V0E A;  4QBW A;  3N0A A;  1XBO A;  4JBC A;  3EZZ A;  3QCC A;  4NWG A;  2F6F A;  2CM8 A;  2PI7 A;  2F70 A;  3V0F A;  4BUB A;  1QZ0 A;  2F6V A;  1J6U A;  3ZM6 A;  2AZR A;  2YDU A;  4ERC A;  1T4J A;  2ZMM A;  2CM3 A;  4RHG A;  2VTD A;  4RKK A;  1BZC A;  4GE2 A;  2HVL A;  1NL9 A;  2CM2 A;  1T48 A;  2F6T A;  1A5Y A;  2QCJ A;  1W78 A;  4CVM A;  2JFF A;  1NWE A;  3EMU A;  3OLR A;  4QUM A;  2HY3 A;  2I6J A;  2DXP A;  4R0S A;  2VOS A;  4UAG A;  4OHE A;  3F9A A;  3V0H A;  3ZM0 A;  2GC6 A;  2Q47 A;  1PTU A;  3LK7 A;  3QCN A;  1JF7 A;  3F41 A;  2PA5 A;  3AWF A;  1D5R A;  2GJT A;  3S4O A;  4GFV A;  2F46 A;  2VEV A;  4KYR A;  4JMJ A;  2P6X A;  3QCE A;  4QF5 A;  4KYQ A;  3A5J A;  3QCZ A;  4HRF A;  1I57 A;  2FH7 A;  1OEM X;  3ZM5 A;  4GWF A;  1YWF A;  5HDE A;  2PSZ A;  2CNE A;  2A8B A;  4TVV A;  3NME A;  2P4D A;  2QBP A;  1ZCK A;  1GQY A;  2NV5 A;  5KA0 A;  2I3U A;  2J17 A;  1RXD A;  2B4S A;  4ZIY A;  2G6Z A;  1PXH A;  4GE5 A;  2CFV A;  4GRY A;  2MBC A;  4YAA A;  3BM8 A;  1OEU A;  2Y67 A;  1ZCL A;  3AWG A;  1PA1 A;  4CVK A;  2Y68 A;  1WCH A;  2OOQ A;  3QCH A;  1EEH A;  2H4K A;  4RDD A;  3BLU A;  4Y14 A;  4IKC A;  1Q6J A;  3D1Q A;  1NWL A;  3QCJ A;  1ECV A;  3D1O A;  3A5K A;  3BLT A;  1WAX A;  1Q6N A;  4C13 A;  4ZN5 A;  3QCI A;  2JFH A;  1JBW A;  2QDC A;  4QBE A;  1ONY A;  3EB1 A;  2UUO A;  3S4E A;  1OES A;  2H4V A;  2I6O A;  3MOZ A;  4NYH A;  4CVL A;  2Y1O A;  1L8G A;  4JMK A;  1VHR A;  3O4S A;  5EHR A;  2A3K A;  5K9V A;  2CMC A;  4HJP A;  3V0G A;  4B04 A;  2VTE A;  4HJQ A;  5KA2 A;  1W7K A;  4QAH A;  2CNG A;  4D3P A;  2CMA A;  3RZ2 A;  1AAX A;  2CM7 A;  2CNH A;  3S3E A;  4GE6 A;  3RO1 A;  2XJA A;  4OHL A;  3PS5 A;  4DGX A;  4YR8 B;  4KI9 A;  4RI4 A;  2SHP A;  3QCG A;  2FJM A;  2QCT A;  5IBM A;  4QDI A;  2F6Y A;  1E0D A;  2HB1 A;  3EAX A;  3D42 A;  1XXV A;  1PTY A;  4PYH A;  1GFY A;  1E8C A;  4S0G A;  5EHP A;  1ZC0 A;  1NZ7 A;  3H2X A;  1G1G A;  2WTZ A;  1G4U S;  2WJP A;  2R0B A;  4WU3 A;  3M4U A;  1YN9 A;  3RGQ A;  2HC1 A;  1OEV A;  1EEN A;  2F6W A;  1YTW A;  5J8R A;  1MKP A;  2Y66 A;  3D9C A;  4WOH A;  4BUC A;  4RH5 A;  5KAC A;  2Y96 A;  3V0J A;  2OZ5 A;  1YPT A;  2PQ5 A;  3S3F A;  2M3V A;  2BZL A;  2HNQ A;  1WRM A;  2Q05 A;  2BIJ A;  2H4G A;  3ZL8 A;  2JJD A;  3QKP A;  2VEX A;  2B3O A;  4WU2 A;  1PTT A;  3QCD A;  1C87 A;  3MOW A;  1G1H A;  3I36 A;  3BRH A;  1L8K A;  2B4O A;  4MBB A;  3ZM3 A;  2OC3 A;  2JFG A;  1U25 A;  3GXH A;  4ZRT A;  2AM2 A;  1LAR A;  2XPC A;  4Y2E A;  2UAG A;  3CWE A;  1I9S A;  2Y2F A;  1C83 A;  2GCA A;  2C46 A;  2CMB A;  5MMZ B;  1G1F A;  2I6I A;  2J16 A;  3EU0 A;  3UAG A;  1YGU A;  2J16 B;  1JBV A;  5K23 A;  5A5F A;  3O5X A;  1G4W R;  2GWO A;  1SUG A;  1YFO A;  2CNF A;  3I80 A;  3O4U A;  5KA7 A;  3GXG A;  5AWX A;  2ESB A;  2VOR A;  4GRZ A;  2B4P A;  3LJ8 A;  1O5Z A;  4R0T A;  4GS0 A;  4OHH A;  1JLN A;  1QXK A;  5K25 A;  2AHS A;  2CNI A;  2HC2 A;  1FPZ A;  5K9W A;  3PYZ A;  1PTV A;  1R6H A;  2HNP A;  4J51 A;  1NO6 A;  5KA3 A;  3ZV2 A;  1X24 A;  3N2A A;  5BUG A;  1Q6M A;  5LXQ B;  1OEO X;  1YZ4 A;  1C88 A;  2NLK A;  3U96 A;  2ZN7 A;  4C12 A;  5BX1 A;  3O3L A;  2X5O A;  3S3H A;  4OHI A;  3NRS A;  3ZM2 A;  1GWZ A;  2VEU A;  2WGP A;  2B07 A;  2I4G A;  3MMJ A;  2F00 A;  1G7G A;  2QEP A;  1P3D A;  5KAA A;  1Q6P A;  1U24 A;  3MVN A;  2H04 A;  1G7F A;  2QBR A;  2B49 A;  1Q6T A;  1GQQ A;  2NTA A;  4NWF A;  3QCF A;  4R30 A;  2BGD A;  4JNB A;  2I6P A;  3F9B A;  2BV5 A;  1UAG A;  2F6Z A;  2NZ6 A;  2BGE A;  2UUP A;  3V0D A;  1C84 A;  2QBS A;  3QCM A;  5KAD A;  4BJO A;  5KAB A;  3QKQ A;  2RF6 A;  2NT7 A;  4H34 A;  5GTJ A;  1XM2 A;  3ZMP A;  2H03 A;  3B7O A;  1T49 A;  2CJZ A;  4D3R A;  5KA1 A;  2I5X A;  3QCK A;  2AM1 A;  3SR9 A;  1V3A A;  1LQF A;  2VEW A;  4HV4 A;  1GG4 A;  1KAK A;  2GP0 A;  5BZZ A;  4ZI4 A;  2I3R A;  4WTY A;  1ONZ A;  4Z6B A;  1OHE A;  3OMH A;  1LYV A;  4QUN A;  2B4U A;  2GCB A;  1KAV A;  3RGO A;  1I9T A;  2C7S A;  2QDM A;  3D1H A;  1P31 A;  1YGR A;  2PT0 A;  2I75 A;  2I4E A;  2PBN A;  2VEY A;  3SME A;  2NT2 A;  2I6M A;  2E0T A;  3AWE A;  4ICZ A;  1NNY A;  1FQ1 A;  1YTS A;  1ZZW A;  1RPM A;  4H1O A;  2HCM A;  2I4H A;  5I6V A;  4BPC A;  4OHD A;  1XRI A;  1C86 A;  1PH0 A;  1PYN A;  5IBS A;  5KA4 A;  4QAP A;  5K24 A;  5KA8 A;  3S3K A;  1U26 A;  2QDP A;  2OUD A;  3D44 A;  1PA9 A;  3QCL A;  1EEO A;  1C85 A;  1OET A;  3CM3 A;  2HXP A;  2I42 A;  4D3Q A;  1OHC A;  4AZ1 A;  3I7Z A;  2H02 A;  5K22 A;  2QBQ A;  1OHD A;  3O4T A;  1J4X A;  4NX8 A;  4I8N A;  1FPR A;  3F81 A;  4NND A;  2IMG A;  2GC5 A;  1XXP A;  1M3G A;  2I1Y A;  4PVG A;  5BZX A;  2F71 A;  4RI5 A;  4GFU A;  1BZJ A;  3HN7 A;  3ZM1 A;  1BZH A;  5M43 A;  3V0I A;  1Q6S A;  5A5E A;  2G59 A;  1FGS A;  1YTN A;  3ZMQ A;  1Q1M A;  3QCB A;  3F99 A; 
#chains in the Genus database with same CATH homology
 4RH9 A;  5KA9 A;  4DGP A;  1P15 A;  2FJN A;  3V0E A;  4QBW A;  3N0A A;  1XBO A;  4JBC A;  3EZZ A;  3QCC A;  4NWG A;  2F6F A;  2CM8 A;  2PI7 A;  2F70 A;  3V0F A;  1QZ0 A;  2F6V A;  2AZR A;  2YDU A;  4ERC A;  1T4J A;  2ZMM A;  2CM3 A;  4RHG A;  4RKK A;  1BZC A;  4GE2 A;  2HVL A;  1NL9 A;  2CM2 A;  1T48 A;  2F6T A;  1A5Y A;  2QCJ A;  1NWE A;  3EMU A;  3OLR A;  4QUM A;  2HY3 A;  2I6J A;  2DXP A;  4R0S A;  4OHE A;  3F9A A;  3V0H A;  3ZM0 A;  2Q47 A;  1PTU A;  3QCN A;  1JF7 A;  3F41 A;  2PA5 A;  3AWF A;  1D5R A;  2GJT A;  3S4O A;  4GFV A;  2F46 A;  2VEV A;  4KYR A;  4JMJ A;  2P6X A;  3QCE A;  4KYQ A;  3A5J A;  4HRF A;  1I57 A;  2FH7 A;  1OEM X;  4GWF A;  1YWF A;  5HDE A;  2PSZ A;  2CNE A;  2A8B A;  4TVV A;  3NME A;  2P4D A;  2QBP A;  1ZCK A;  2NV5 A;  5KA0 A;  2I3U A;  2J17 A;  1RXD A;  2B4S A;  2G6Z A;  1PXH A;  4GE5 A;  2CFV A;  4GRY A;  2MBC A;  4YAA A;  3BM8 A;  1OEU A;  1ZCL A;  3AWG A;  1PA1 A;  1WCH A;  3QCH A;  2OOQ A;  2H4K A;  4RDD A;  3BLU A;  4Y14 A;  4IKC A;  1Q6J A;  3D1Q A;  1NWL A;  3QCJ A;  1ECV A;  3D1O A;  3A5K A;  3BLT A;  1WAX A;  1Q6N A;  4ZN5 A;  3QCI A;  2QDC A;  4QBE A;  1ONY A;  3EB1 A;  3S4E A;  1OES A;  2H4V A;  2I6O A;  3MOZ A;  4NYH A;  1L8G A;  4JMK A;  1VHR A;  3O4S A;  5EHR A;  2A3K A;  5K9V A;  2CMC A;  4HJP A;  3V0G A;  4B04 A;  4HJQ A;  5KA2 A;  4QAH A;  2CNG A;  4D3P A;  2CMA A;  3RZ2 A;  1AAX A;  2CM7 A;  2CNH A;  3S3E A;  4GE6 A;  3RO1 A;  4OHL A;  3PS5 A;  4DGX A;  4YR8 B;  4KI9 A;  4RI4 A;  2SHP A;  3QCG A;  2FJM A;  2QCT A;  5IBM A;  2F6Y A;  2HB1 A;  3EAX A;  3D42 A;  1XXV A;  1PTY A;  4PYH A;  1GFY A;  4S0G A;  5EHP A;  1ZC0 A;  1NZ7 A;  3H2X A;  1G1G A;  1G4U S;  2R0B A;  4WU3 A;  3M4U A;  1YN9 A;  3RGQ A;  2HC1 A;  1OEV A;  1EEN A;  2F6W A;  1YTW A;  5J8R A;  1MKP A;  3D9C A;  4WOH A;  4RH5 A;  5KAC A;  2Y96 A;  3V0J A;  2OZ5 A;  1YPT A;  2PQ5 A;  3S3F A;  2M3V A;  2BZL A;  2HNQ A;  1WRM A;  2Q05 A;  2BIJ A;  2H4G A;  2JJD A;  3QKP A;  2VEX A;  2B3O A;  4WU2 A;  1PTT A;  3QCD A;  1C87 A;  3MOW A;  1G1H A;  3I36 A;  3BRH A;  1L8K A;  2B4O A;  4MBB A;  3ZM3 A;  2OC3 A;  1U25 A;  3GXH A;  4ZRT A;  1LAR A;  4Y2E A;  3CWE A;  1I9S A;  2Y2F A;  1C83 A;  2C46 A;  2CMB A;  5MMZ B;  1G1F A;  2I6I A;  2J16 A;  3EU0 A;  1YGU A;  2J16 B;  5K23 A;  3O5X A;  1G4W R;  2GWO A;  1SUG A;  1YFO A;  2CNF A;  3I80 A;  3O4U A;  5KA7 A;  3GXG A;  5AWX A;  2ESB A;  4GRZ A;  2B4P A;  3LJ8 A;  4R0T A;  4GS0 A;  4OHH A;  1JLN A;  1QXK A;  5K25 A;  2AHS A;  2CNI A;  2HC2 A;  1FPZ A;  5K9W A;  1PTV A;  1R6H A;  2HNP A;  4J51 A;  1NO6 A;  5KA3 A;  3ZV2 A;  1X24 A;  5BUG A;  1Q6M A;  5LXQ B;  1OEO X;  1YZ4 A;  1C88 A;  2NLK A;  3U96 A;  2ZN7 A;  5BX1 A;  3O3L A;  3S3H A;  4OHI A;  3ZM2 A;  1GWZ A;  2VEU A;  2WGP A;  2B07 A;  2I4G A;  3MMJ A;  1G7G A;  2QEP A;  5KAA A;  1Q6P A;  1U24 A;  2H04 A;  1G7F A;  2QBR A;  2B49 A;  1Q6T A;  2NTA A;  4NWF A;  3QCF A;  4R30 A;  2BGD A;  4JNB A;  3F9B A;  2I6P A;  2BV5 A;  2F6Z A;  2NZ6 A;  2BGE A;  3V0D A;  1C84 A;  2QBS A;  3QCM A;  5KAD A;  4BJO A;  5KAB A;  3QKQ A;  2RF6 A;  2NT7 A;  4H34 A;  5GTJ A;  1XM2 A;  3ZMP A;  2H03 A;  3B7O A;  1T49 A;  2CJZ A;  4D3R A;  5KA1 A;  2I5X A;  3QCK A;  3SR9 A;  1V3A A;  1LQF A;  2VEW A;  1KAK A;  2GP0 A;  5BZZ A;  4ZI4 A;  2I3R A;  4WTY A;  1ONZ A;  4Z6B A;  1OHE A;  3OMH A;  1LYV A;  4QUN A;  2B4U A;  1KAV A;  3RGO A;  1I9T A;  2C7S A;  2QDM A;  3D1H A;  1YGR A;  2PT0 A;  2I75 A;  2I4E A;  2PBN A;  2VEY A;  3SME A;  2NT2 A;  2I6M A;  2E0T A;  3AWE A;  4ICZ A;  1NNY A;  1FQ1 A;  1YTS A;  1ZZW A;  1RPM A;  4H1O A;  2HCM A;  2I4H A;  5I6V A;  4BPC A;  4OHD A;  1XRI A;  1C86 A;  1PH0 A;  1PYN A;  5IBS A;  5KA4 A;  4QAP A;  5K24 A;  5KA8 A;  3S3K A;  1U26 A;  2QDP A;  2OUD A;  3D44 A;  1PA9 A;  3QCL A;  1EEO A;  1C85 A;  1OET A;  3CM3 A;  2HXP A;  2I42 A;  4D3Q A;  1OHC A;  4AZ1 A;  3I7Z A;  2H02 A;  5K22 A;  2QBQ A;  1OHD A;  3O4T A;  1J4X A;  4NX8 A;  4I8N A;  1FPR A;  3F81 A;  4NND A;  2IMG A;  1XXP A;  1M3G A;  2I1Y A;  4PVG A;  5BZX A;  2F71 A;  4RI5 A;  4GFU A;  1BZJ A;  3ZM1 A;  1BZH A;  5M43 A;  3V0I A;  1Q6S A;  2G59 A;  1YTN A;  3ZMQ A;  1Q1M A;  3QCB A;  3F99 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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