1FSSB

Acetylcholinesterase (e.c. 3.1.1.7) complexed with fasciculin-ii
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
61
structure length
61
Chain Sequence
TMCYSHTTTSRAILTNCGENSCYRKSRRHPPKMVLGRGCGCPPGDDNLEVKCCTSPDKCNY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ACETYLCHOLINESTERASE
publication title Crystal structure of an acetylcholinesterase-fasciculin complex: interaction of a three-fingered toxin from snake venom with its target.
pubmed doi rcsb
molecule tags Complex (serine esterase/toxin)
total genus 8
structure length 61
sequence length 61
ec nomenclature
pdb deposition date 1995-10-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1fssB00
2BTXA 1IDGA 4DO8A 2ABXA 2MUOA 2FD6U 4IYEA 3NH7A 1L4WA 1VB0A 1RL5A 2UWRA 1TXBA 1JBDA 3QB4B 1JGKA 2QJBC 1HAJA 5IMTD 2PJYB 1LSIA 1TXAA 2H62C 2QJ9C 1LJZA 2L5SA 1H0JA 3NDSA 2H5FA 1KU6B 2MFAA 1CHVS 2PJYC 4BDTB 1F8UB 1HC9B 1TFSA 4QTIU 1ZADA 2LCRA 3EBXA 2VLWA 1KTZB 1ES7B 1CTXA 1LXHA 2QJAC 2H64C 1CRFA 2K3GA 1RGJA 2X8BB 1LXGA 4BIKB 2J8BA 1NORA 2CRSA 2MUPA 3LAQU 4LFTA 1IDLA 1FF4A 5EBXA 1KC4A 2LA1A 1S4YA 3BT1U 2BHIA 1CDTA 1UG4A 4OM4A 4UY2C 1CXNA 1M9ZA 3HH7A 1B41B 1ABTA 2CRTA 2NBTA 1KS6A 1IKCA 4RUDA 1NYUA 4ZQYA 1I02A 1NYSA 1NEAA 1QKDA 1NXBA 1KBTA 1ONJA 2H7ZA 2N99A 4OM5A 5IMYC 3KFDI 1FASA 1G6MA 2MHYA 5DO6A 2CDXA 2CCXA 1F94A 2UX2A 1REWC 1IDHA 4FAOE 2MJ0A 2OFSA 1IJCA 1MR6A 1ERAA 2ERAA 1CDQA 1CVOA 2L03A 3EVSC 1PLOA 3PLCA 1XT3A 2MJYA 1BTEA 2MJ4A 3U74U 2H8UA 1HOYA 1IK8A 4EY8B 1CODA 1V6PA 4FAOC 3NEQA 3ERAA 3KFDE 3U73U 1FSCA 1JE9A 1HAAA 2JQPA 6EBXA 1BXPA 1LX5B 2GOOB 1MAHF 2HLQA 1W6BA 4HQPF 1NTNA 4XJJA 1COEA 1IQ9A 1IDIA 1YWHA 3VTSA 2QC1A 1CDSA 1CXOA 1CB9A 2I9BE 2GOOC 5DU1A 1KL8A 2H7ZB 1CDRA 1FFJA 1QM7A 3FEVA 1ERGA 1FSSB 1KFHA 2JVEA 1QKEA 1HC9A 1NTXA 2H62D 5DZ5A 1KBAA 4AEAA 4P7UA 2H64B 3BT2U 1KXIA 1TGXA 1FRAA 1CCQA 1KBSA 1DRSA 1CREA 2HLRA 2CTXA
chains in the Genus database with same CATH superfamily
2BTXA 1IDGA 4DO8A 2ABXA 2MUOA 2FD6U 4IYEA 3NH7A 1L4WA 1VB0A 1RL5A 2UWRA 1TXBA 1JBDA 3QB4B 1JGKA 2QJBC 1HAJA 5IMTD 2PJYB 1LSIA 1TXAA 2H62C 2QJ9C 1LJZA 2L5SA 1H0JA 3NDSA 2H5FA 1KU6B 2MFAA 1CHVS 2PJYC 4BDTB 1F8UB 1HC9B 1TFSA 4QTIU 1ZADA 2LCRA 3EBXA 2VLWA 1KTZB 1ES7B 1CTXA 1LXHA 2QJAC 2H64C 1CRFA 2K3GA 1RGJA 2X8BB 1LXGA 4BIKB 2J8BA 1NORA 2CRSA 2MUPA 3LAQU 4LFTA 1IDLA 1FF4A 5EBXA 1KC4A 2LA1A 1S4YA 3BT1U 2BHIA 1CDTA 1UG4A 4OM4A 4UY2C 1CXNA 1M9ZA 3HH7A 1B41B 1ABTA 4KSNA 2CRTA 2NBTA 1KS6A 1IKCA 4RUDA 1NYUA 4ZQYA 1I02A 1NYSA 1NEAA 1QKDA 1NXBA 1KBTA 1ONJA 2H7ZA 2N99A 4OM5A 5IMYC 3KFDI 1FASA 1G6MA 2MHYA 5DO6A 2CDXA 2CCXA 1F94A 2UX2A 1REWC 1IDHA 4FAOE 2MJ0A 2OFSA 1IJCA 1MR6A 1ERAA 2ERAA 1CDQA 1CVOA 2L03A 3EVSC 1PLOA 3PLCA 1XT3A 2MJYA 1BTEA 2MJ4A 3U74U 2H8UA 1HOYA 1IK8A 4EY8B 1CODA 1V6PA 4FAOC 3NEQA 3ERAA 3KFDE 3U73U 1FSCA 1JE9A 1HAAA 2JQPA 6EBXA 1BXPA 1LX5B 2GOOB 1MAHF 2HLQA 1W6BA 4HQPF 1NTNA 4XJJA 1COEA 1IQ9A 1IDIA 1YWHA 3VTSA 2QC1A 1CDSA 1CXOA 1CB9A 2I9BE 2GOOC 5DU1A 1KL8A 2H7ZB 1CDRA 1FFJA 1QM7A 3FEVA 1ERGA 1FSSB 1KFHA 2JVEA 1QKEA 1HC9A 1NTXA 2H62D 5DZ5A 1KBAA 4AEAA 4P7UA 2H64B 3BT2U 1KXIA 1TGXA 1FRAA 1CCQA 1KBSA 1DRSA 1CREA 2HLRA 2CTXA
chains in the Genus database with same CATH topology
2BTXA 1IDGA 4DO8A 2ABXA 2MUOA 2FD6U 4IYEA 3NH7A 1L4WA 1VB0A 1RL5A 2UWRA 1TXBA 1JBDA 3QB4B 1JGKA 2QJBC 1HAJA 5IMTD 2PJYB 1LSIA 1TXAA 2H62C 2QJ9C 1LJZA 2L5SA 1H0JA 3NDSA 2H5FA 1KU6B 2MFAA 1CHVS 2PJYC 4BDTB 1F8UB 1HC9B 1TFSA 4QTIU 1ZADA 2LCRA 3EBXA 2VLWA 1KTZB 1ES7B 1CTXA 1LXHA 2QJAC 2H64C 1CRFA 2K3GA 1RGJA 2X8BB 1LXGA 4BIKB 2J8BA 1NORA 2CRSA 2MUPA 3LAQU 4LFTA 1IDLA 1FF4A 5EBXA 1KC4A 2LA1A 1S4YA 3BT1U 2BHIA 1CDTA 1UG4A 4OM4A 4UY2C 1CXNA 1M9ZA 3HH7A 1B41B 1ABTA 4KSNA 2CRTA 2NBTA 1KS6A 1IKCA 4RUDA 1NYUA 4ZQYA 1I02A 1NYSA 1NEAA 1QKDA 1NXBA 1KBTA 1ONJA 2H7ZA 2N99A 4OM5A 5IMYC 3KFDI 1FASA 1G6MA 2MHYA 5DO6A 2CDXA 2CCXA 1F94A 2UX2A 1REWC 1IDHA 4FAOE 2MJ0A 2OFSA 1IJCA 1MR6A 1ERAA 2ERAA 1CDQA 1CVOA 2L03A 3EVSC 1PLOA 3PLCA 1XT3A 2MJYA 1BTEA 2MJ4A 3U74U 2H8UA 1HOYA 1IK8A 4EY8B 1CODA 1V6PA 4FAOC 3NEQA 3ERAA 3KFDE 3U73U 1FSCA 1JE9A 1HAAA 2JQPA 6EBXA 1BXPA 1LX5B 2GOOB 1MAHF 2HLQA 1W6BA 4HQPF 1NTNA 4XJJA 1COEA 1IQ9A 1IDIA 1YWHA 3VTSA 2QC1A 1CDSA 1CXOA 1CB9A 2I9BE 2GOOC 5DU1A 1KL8A 2H7ZB 1CDRA 1FFJA 1QM7A 3FEVA 1ERGA 1FSSB 1KFHA 2JVEA 1QKEA 1HC9A 1NTXA 2H62D 5DZ5A 1KBAA 4AEAA 4P7UA 2H64B 3BT2U 1KXIA 1TGXA 1FRAA 1CCQA 1KBSA 1DRSA 1CREA 2HLRA 2CTXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BTX A;  1IDG A;  4DO8 A;  2ABX A;  2MUO A;  2FD6 U;  4IYE A;  3NH7 A;  1L4W A;  1VB0 A;  1RL5 A;  2UWR A;  1TXB A;  1JBD A;  3QB4 B;  1JGK A;  2QJB C;  1HAJ A;  5IMT D;  2PJY B;  1LSI A;  1TXA A;  2H62 C;  2QJ9 C;  1LJZ A;  2L5S A;  1H0J A;  3NDS A;  2H5F A;  1KU6 B;  2MFA A;  1CHV S;  2PJY C;  4BDT B;  1F8U B;  1HC9 B;  1TFS A;  4QTI U;  1ZAD A;  2LCR A;  3EBX A;  2VLW A;  1KTZ B;  1ES7 B;  1CTX A;  1LXH A;  2QJA C;  2H64 C;  1CRF A;  2K3G A;  1RGJ A;  2X8B B;  1LXG A;  4BIK B;  2J8B A;  1NOR A;  2CRS A;  2MUP A;  3LAQ U;  4LFT A;  1IDL A;  1FF4 A;  5EBX A;  1KC4 A;  2LA1 A;  1S4Y A;  3BT1 U;  2BHI A;  1CDT A;  1UG4 A;  4OM4 A;  4UY2 C;  1CXN A;  1M9Z A;  3HH7 A;  1B41 B;  1ABT A;  2CRT A;  2NBT A;  1KS6 A;  1IKC A;  4RUD A;  1NYU A;  4ZQY A;  1I02 A;  1NYS A;  1NEA A;  1QKD A;  1NXB A;  1KBT A;  1ONJ A;  2H7Z A;  2N99 A;  4OM5 A;  5IMY C;  3KFD I;  1FAS A;  1G6M A;  2MHY A;  5DO6 A;  2CDX A;  2CCX A;  1F94 A;  2UX2 A;  1REW C;  1IDH A;  4FAO E;  2MJ0 A;  2OFS A;  1IJC A;  1MR6 A;  1ERA A;  2ERA A;  1CDQ A;  1CVO A;  2L03 A;  3EVS C;  1PLO A;  3PLC A;  1XT3 A;  2MJY A;  1BTE A;  2MJ4 A;  3U74 U;  2H8U A;  1HOY A;  1IK8 A;  4EY8 B;  1COD A;  1V6P A;  4FAO C;  3NEQ A;  3ERA A;  3KFD E;  3U73 U;  1FSC A;  1JE9 A;  1HAA A;  2JQP A;  6EBX A;  1BXP A;  1LX5 B;  2GOO B;  1MAH F;  2HLQ A;  1W6B A;  4HQP F;  1NTN A;  4XJJ A;  1COE A;  1IQ9 A;  1IDI A;  1YWH A;  3VTS A;  2QC1 A;  1CDS A;  1CXO A;  1CB9 A;  2I9B E;  2GOO C;  5DU1 A;  1KL8 A;  2H7Z B;  1CDR A;  1FFJ A;  1QM7 A;  3FEV A;  1ERG A;  1FSS B;  1KFH A;  2JVE A;  1QKE A;  1HC9 A;  1NTX A;  2H62 D;  5DZ5 A;  1KBA A;  4AEA A;  4P7U A;  2H64 B;  3BT2 U;  1KXI A;  1TGX A;  1FRA A;  1CCQ A;  1KBS A;  1DRS A;  1CRE A;  2HLR A;  2CTX A; 
#chains in the Genus database with same CATH topology
 2BTX A;  1IDG A;  4DO8 A;  2ABX A;  2MUO A;  2FD6 U;  4IYE A;  3NH7 A;  1L4W A;  1VB0 A;  1RL5 A;  2UWR A;  1TXB A;  1JBD A;  3QB4 B;  1JGK A;  2QJB C;  1HAJ A;  5IMT D;  2PJY B;  1LSI A;  1TXA A;  2H62 C;  2QJ9 C;  1LJZ A;  2L5S A;  1H0J A;  3NDS A;  2H5F A;  1KU6 B;  2MFA A;  1CHV S;  2PJY C;  4BDT B;  1F8U B;  1HC9 B;  1TFS A;  4QTI U;  1ZAD A;  2LCR A;  3EBX A;  2VLW A;  1KTZ B;  1ES7 B;  1CTX A;  1LXH A;  2QJA C;  2H64 C;  1CRF A;  2K3G A;  1RGJ A;  2X8B B;  1LXG A;  4BIK B;  2J8B A;  1NOR A;  2CRS A;  2MUP A;  3LAQ U;  4LFT A;  1IDL A;  1FF4 A;  5EBX A;  1KC4 A;  2LA1 A;  1S4Y A;  3BT1 U;  2BHI A;  1CDT A;  1UG4 A;  4OM4 A;  4UY2 C;  1CXN A;  1M9Z A;  3HH7 A;  1B41 B;  1ABT A;  4KSN A;  2CRT A;  2NBT A;  1KS6 A;  1IKC A;  4RUD A;  1NYU A;  4ZQY A;  1I02 A;  1NYS A;  1NEA A;  1QKD A;  1NXB A;  1KBT A;  1ONJ A;  2H7Z A;  2N99 A;  4OM5 A;  5IMY C;  3KFD I;  1FAS A;  1G6M A;  2MHY A;  5DO6 A;  2CDX A;  2CCX A;  1F94 A;  2UX2 A;  1REW C;  1IDH A;  4FAO E;  2MJ0 A;  2OFS A;  1IJC A;  1MR6 A;  1ERA A;  2ERA A;  1CDQ A;  1CVO A;  2L03 A;  3EVS C;  1PLO A;  3PLC A;  1XT3 A;  2MJY A;  1BTE A;  2MJ4 A;  3U74 U;  2H8U A;  1HOY A;  1IK8 A;  4EY8 B;  1COD A;  1V6P A;  4FAO C;  3NEQ A;  3ERA A;  3KFD E;  3U73 U;  1FSC A;  1JE9 A;  1HAA A;  2JQP A;  6EBX A;  1BXP A;  1LX5 B;  2GOO B;  1MAH F;  2HLQ A;  1W6B A;  4HQP F;  1NTN A;  4XJJ A;  1COE A;  1IQ9 A;  1IDI A;  1YWH A;  3VTS A;  2QC1 A;  1CDS A;  1CXO A;  1CB9 A;  2I9B E;  2GOO C;  5DU1 A;  1KL8 A;  2H7Z B;  1CDR A;  1FFJ A;  1QM7 A;  3FEV A;  1ERG A;  1FSS B;  1KFH A;  2JVE A;  1QKE A;  1HC9 A;  1NTX A;  2H62 D;  5DZ5 A;  1KBA A;  4AEA A;  4P7U A;  2H64 B;  3BT2 U;  1KXI A;  1TGX A;  1FRA A;  1CCQ A;  1KBS A;  1DRS A;  1CRE A;  2HLR A;  2CTX A; 
#chains in the Genus database with same CATH homology
 2BTX A;  1IDG A;  4DO8 A;  2ABX A;  2MUO A;  2FD6 U;  4IYE A;  3NH7 A;  1L4W A;  1VB0 A;  1RL5 A;  2UWR A;  1TXB A;  1JBD A;  3QB4 B;  1JGK A;  2QJB C;  1HAJ A;  5IMT D;  2PJY B;  1LSI A;  1TXA A;  2H62 C;  2QJ9 C;  1LJZ A;  2L5S A;  1H0J A;  3NDS A;  2H5F A;  1KU6 B;  2MFA A;  1CHV S;  2PJY C;  4BDT B;  1F8U B;  1HC9 B;  1TFS A;  4QTI U;  1ZAD A;  2LCR A;  3EBX A;  2VLW A;  1KTZ B;  1ES7 B;  1CTX A;  1LXH A;  2QJA C;  2H64 C;  1CRF A;  2K3G A;  1RGJ A;  2X8B B;  1LXG A;  4BIK B;  2J8B A;  1NOR A;  2CRS A;  2MUP A;  3LAQ U;  4LFT A;  1IDL A;  1FF4 A;  5EBX A;  1KC4 A;  2LA1 A;  1S4Y A;  3BT1 U;  2BHI A;  1CDT A;  1UG4 A;  4OM4 A;  4UY2 C;  1CXN A;  1M9Z A;  3HH7 A;  1B41 B;  1ABT A;  4KSN A;  2CRT A;  2NBT A;  1KS6 A;  1IKC A;  4RUD A;  1NYU A;  4ZQY A;  1I02 A;  1NYS A;  1NEA A;  1QKD A;  1NXB A;  1KBT A;  1ONJ A;  2H7Z A;  2N99 A;  4OM5 A;  5IMY C;  3KFD I;  1FAS A;  1G6M A;  2MHY A;  5DO6 A;  2CDX A;  2CCX A;  1F94 A;  2UX2 A;  1REW C;  1IDH A;  4FAO E;  2MJ0 A;  2OFS A;  1IJC A;  1MR6 A;  1ERA A;  2ERA A;  1CDQ A;  1CVO A;  2L03 A;  3EVS C;  1PLO A;  3PLC A;  1XT3 A;  2MJY A;  1BTE A;  2MJ4 A;  3U74 U;  2H8U A;  1HOY A;  1IK8 A;  4EY8 B;  1COD A;  1V6P A;  4FAO C;  3NEQ A;  3ERA A;  3KFD E;  3U73 U;  1FSC A;  1JE9 A;  1HAA A;  2JQP A;  6EBX A;  1BXP A;  1LX5 B;  2GOO B;  1MAH F;  2HLQ A;  1W6B A;  4HQP F;  1NTN A;  4XJJ A;  1COE A;  1IQ9 A;  1IDI A;  1YWH A;  3VTS A;  2QC1 A;  1CDS A;  1CXO A;  1CB9 A;  2I9B E;  2GOO C;  5DU1 A;  1KL8 A;  2H7Z B;  1CDR A;  1FFJ A;  1QM7 A;  3FEV A;  1ERG A;  1FSS B;  1KFH A;  2JVE A;  1QKE A;  1HC9 A;  1NTX A;  2H62 D;  5DZ5 A;  1KBA A;  4AEA A;  4P7U A;  2H64 B;  3BT2 U;  1KXI A;  1TGX A;  1FRA A;  1CCQ A;  1KBS A;  1DRS A;  1CRE A;  2HLR A;  2CTX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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