1G05A

Heterocycle-based mmp inhibitor with p2'substituents
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
169
structure length
166
Chain Sequence
FRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHDLTRFRLSQDDINGIQSLYGPPPD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Heterocycle-based MMP inhibitors with P2' substituents.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords STROMELYSIN-1 PRECURSOR
total genus 46
structure length 166
sequence length 169
chains with identical sequence B
ec nomenclature ec 3.4.24.17: Stromelysin 1.
pdb deposition date 2000-10-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1g05A00
3EDIA 2K9CA 1SU3A 1HV5A 1KUKA 4FXYP 2JT5A 1SRPA 3TT4A 1OS2A 4L63A 1R1JA 1XUCA 4FU4A 2DDFA 4GQLA 2YIGA 4WK7A 2O36A 4ON1A 4PKSA 2TCLA 4L19A 1YCMA 1EUBA 1MMQA 1K7QA 2XS3A 4CTHA 1UEAA 4HX3A 4IUWA 3TSKA 5I43A 4H30A 3U1RA 1CGFA 1QJIA 1BKCE 3F17A 1ROSA 2AIGP 2OY4A 2OXZA 1OMJA 2OW9A 3DL1A 1SMPA 4WKIA 4IJOA 1D8FA 4G0DA 3F16A 3ZXHA 2WO8A 2W12A 1JJ9A 1HFSA 3KECA 3OHOA 3KMCA 1GE5A 4H1QA 1CAQA 4R3VA 1PWWA 3F1AA 4I03A 1FBLA 2O3EA 4G9LA 1PWQA 5D1TA 1H71P 3DPEA 4A3WA 2K2GA 2PJTA 3E8RA 3HYGA 1JH1A 3LJZA 1HFCA 1I73A 1QUAA 1CGEA 1BKCA 2V4BA 2X7MA 1YOUA 4DD8A 5JMYA 4PKWA 2FV9A 3LE9A 1ZXVA 1SLNA 4JQGA 2FV5A 2YB9A 3LK8A 1JAOA 4Q1LA 1JIZA 1PWVA 3LMCA 4ZR5A 4H2EA 4JA1A 2USNA 1AF0A 1BQQM 3HY9A 3DSLA 1GE6A 1G05A 2OVZA 4I35A 1WNIA 4WZVA 1JKYA 3LJTA 3RTTA 1XFXA 2OW0A 3OHLA 1R55A 2QPJA 3KWVC 4AIGA 1C3IA 1Y8JA 2Y6DA 3I7GA 2AYKA 1OM8A 4XM8A 2I47A 3VI1A 3V96B 3USNA 1UTZA 4IN9A 1CGLA 3F15A 3KEJA 3HDAP 1BZSA 3EDGA 3AYUA 3Q2HA 4EFSA 1G49A 3EHYA 1PWPA 5CXAA 1EAKA 4PKUA 1D7XA 1KUGA 2WO9A 2X3BA 2L0RA 2WOAA 1JANA 1S4BP 2OZRA 4JP4A 1Z3JA 4GWMA 1GO8P 1XFVA 4WF6A 3EDZA 1QICA 3EDHA 1I1IP 2Y6CA 456CA 1BKCI 1ZS0A 4H84A 4DPEA 3B8ZA 3VTGA 4GR8A 2OI0A 1R54A 2OY2A 2HU6A 3LQ0A 2D1NA 1IAGA 1ZTQA 3I7IA 4H49A 1CK7A 4GR3A 2CKIA 1J7NA 3DNGA 3LQBA 1G9KA 2X3CA 1YQYA 1BIWA 1UTTA 1IACA 3ELMA 1A86A 3L0TA 5B5PA 4XCTA 4HMAA 4J4MA 1ZXCA 1Q3AA 4XBHA 1XFZA 2DDYA 2E3XA 2Z2DA 4AUOA 5D1UA 3HBUP 4FXQA 5CZMA 2X3AA 2RJQA 2MLRA 1UMTA 1GXDA 2SRTA 4H3XA 4A7BA 1R1HA 3DWBA 4H82A 1CIZA 3KEKA 4XM6A 4FVLA 5L79A 1XFUA 3TS4A 1B8YA 1KUHA 1PWUA 3AYKA 1USNA 2DW1A 1ATLA 3Q2GA 2RJPA 2OXWA 2D1OA 1GKCA 1RM8A 3G42A 5I12A 1O0TA 4ILWD 3EHXA 3LGPA 5L7FA 4QKZA 3LIKA 3O2XA 2N8RA 5I0LA 5I2ZA 1JK3A 3G5CA 1KUFA 1DMTA 5D2BA 4GR0A 1MNCA 1SLMA 4L6TA 4PKQA 1KUIA 4PKVA 1FM1A 1XFWA 1JAPA 3K7LA 1BQOA 1HY7A 3B2ZA 3N2VA 2J0TA 1KBCA 1R1IA 3LUMA 1ZVXA 3LEAA 4AXQA 1MMPA 1Y93A 3HBVP 3EWJA 3O64A 2XS4A 3KRYA 1G4KA 1D8MA 5BPAA 1I76A 1YP1A 3WV2A 1QJJA 1AKLA 4AYKA 3P24A 2ERQA 1OS9A 2JIHA 2POJA 3WV1A 1CXVA 1XFYA 3P1VA 4H76A 2ERPA 1B3DA 1DTHA 3TVCA 1ND1A 2OW1A 3L0VA 1CQRA 4GUYA 3F19A 3MA2A 5H8XA 1QIAA 1Y0VA 1L6JA 2MZEA 2W13A 1GO7P 4WKEA 2MZHA 5D7WA 3F18A 966CA 5BOYA 2W14A 1K7GA 5B5OA 1OO9A 2W0DA 2A8HA 3LIRA 2DW0A 1BUVM 1HTDA 3LILA 3CKIA 2OXUA 3N2UA 1OM6A 1C7KA 3KMEA 1D5JA 3ZVSA 1K7IA 1MMRA 1O0QA 4GF1A 5D1SA 3LKAA 1RMZA 1MMBA 1IADA 1JAQA 1GKDA 1IAEA 4JIJA 1HOVA 1XUDA 5I3MA 3GBOA 3UVCA 2MLSA 1ASTA 1GE7A 3LUNA 4PKTA 1BM6A 2EROA 1KAPP 3SHIA 1BSWA 3BA0A 5CUHA 5BOTA 1IABA 2JT6A 1G12A 4GWNA 1AYKA 830CA 1SATA 2W15A 3ZUKA 3NX7A 3HDBA 5D3CA 4DF9A 2JSDA 1C8TA 1XURA 4JPAA 1UMSA 4XM7A 1BUDA 1FLSA 3RTSA 3KHIA 2OVXA 3AIGA 2MZIA 3HB2P 3LJGA 2DW2A 3B92A 1IAAA 4PKRA 2JNPA 3DPFA 1ZP5A 2OW2A 2KRJA 5LABA 3WV3A 2J83A 1EB6A 1A85A 1JIWP 2CLTA 4DV8A 3K7NA 1QIBA 2E2DA 3HY7A 1OM7A 5I4OA
chains in the Genus database with same CATH superfamily
3EDIA 2K9CA 1SU3A 1HV5A 4L7AA 1KUKA 4FXYP 2JT5A 1SRPA 3TT4A 1OS2A 4L63A 1R1JA 1XUCA 4FU4A 2DDFA 4GQLA 2YIGA 4WK7A 2O36A 4ON1A 4PKSA 2TCLA 4L19A 1YCMA 1EUBA 1MMQA 1K7QA 2XS3A 4CTHA 1UEAA 4HX3A 4IUWA 3TSKA 5I43A 4H30A 3U1RA 1CGFA 1QJIA 1BKCE 3F17A 1ROSA 2AIGP 2OY4A 2OXZA 1OMJA 2OW9A 3DL1A 1SMPA 4WKIA 4IJOA 1D8FA 4G0DA 3F16A 3ZXHA 2WO8A 2W12A 1JJ9A 1HFSA 3KECA 3OHOA 3KMCA 1GE5A 4H1QA 1CAQA 4R3VA 1PWWA 3F1AA 4I03A 1FBLA 2O3EA 4G9LA 1PWQA 5D1TA 1H71P 3DPEA 4A3WA 2K2GA 2PJTA 3E8RA 3HYGA 1JH1A 3LJZA 1HFCA 1I73A 1QUAA 1CGEA 1BKCA 2V4BA 2X7MA 1YOUA 4DD8A 5JMYA 4PKWA 2FV9A 3LE9A 1ZXVA 1SLNA 1XM5A 4JQGA 2FV5A 2YB9A 2YUFA 3LK8A 1JAOA 1TVIA 4Q1LA 1JIZA 1PWVA 3LMCA 4ZR5A 4H2EA 4JA1A 2USNA 1AF0A 1BQQM 3HY9A 3DSLA 1GE6A 1G05A 2OVZA 4I35A 1WNIA 4WZVA 1JKYA 3LJTA 3RTTA 1XFXA 2OW0A 3OHLA 1R55A 2QPJA 3KWVC 4AIGA 1C3IA 1Y8JA 2Y6DA 3I7GA 2AYKA 1OM8A 4XM8A 2I47A 3VI1A 3V96B 3USNA 1UTZA 4IN9A 1CGLA 3F15A 3KEJA 3HDAP 1BZSA 3EDGA 3AYUA 3Q2HA 4EFSA 1G49A 3EHYA 1PWPA 5CXAA 1EAKA 4PKUA 1D7XA 1KUGA 2WO9A 2X3BA 2L0RA 2WOAA 1JANA 1S4BP 2OZRA 4JP4A 1Z3JA 4GWMA 1GO8P 1XFVA 4WF6A 3EDZA 1QICA 3EDHA 1I1IP 2Y6CA 456CA 1BKCI 1ZS0A 4H84A 4DPEA 3B8ZA 3VTGA 4GR8A 2OI0A 1R54A 2OY2A 2HU6A 3LQ0A 2D1NA 1IAGA 1ZTQA 3I7IA 4H49A 1CK7A 4GR3A 2CKIA 1J7NA 3DNGA 3LQBA 1G9KA 2X3CA 1YQYA 1BIWA 1UTTA 1IACA 3ELMA 1A86A 3L0TA 5B5PA 4XCTA 4HMAA 4J4MA 1ZXCA 1Q3AA 4XBHA 1XFZA 2DDYA 2E3XA 2Z2DA 4AUOA 5D1UA 3HBUP 4FXQA 5CZMA 2X3AA 2RJQA 2MLRA 1UMTA 1GXDA 2SRTA 4H3XA 4A7BA 1R1HA 3DWBA 4H82A 1CIZA 3KEKA 4XM6A 4FVLA 5L79A 1XFUA 3TS4A 1B8YA 1KUHA 1PWUA 3AYKA 1USNA 2DW1A 1ATLA 3Q2GA 2RJPA 2OXWA 2D1OA 1GKCA 1RM8A 3G42A 5I12A 1O0TA 4ILWD 3EHXA 3LGPA 5L7FA 4QKZA 3LIKA 3O2XA 2N8RA 5I0LA 5I2ZA 1JK3A 3G5CA 1KUFA 1DMTA 5D2BA 4GR0A 1MNCA 1SLMA 4L6TA 4PKQA 1KUIA 4PKVA 1FM1A 1XFWA 1JAPA 3K7LA 1BQOA 1HY7A 3B2ZA 3N2VA 2J0TA 1KBCA 1R1IA 3LUMA 1ZVXA 3LEAA 4AXQA 1MMPA 1Y93A 3HBVP 3EWJA 3O64A 2XS4A 3KRYA 1G4KA 1D8MA 5BPAA 1I76A 1YP1A 3WV2A 1QJJA 3DTEA 1AKLA 4AYKA 3P24A 2ERQA 1OS9A 2JIHA 2POJA 3WV1A 1CXVA 1XFYA 3P1VA 4H76A 2ERPA 1B3DA 1DTHA 3TVCA 1ND1A 2OW1A 3L0VA 1CQRA 4GUYA 3F19A 3MA2A 5H8XA 1QIAA 1Y0VA 1L6JA 2MZEA 2W13A 1GO7P 4WKEA 2MZHA 5D7WA 3F18A 966CA 5BOYA 2W14A 1K7GA 5B5OA 1XAXA 1OO9A 2W0DA 2A8HA 3LIRA 2DW0A 1BUVM 1HTDA 3LILA 3CKIA 2OXUA 3N2UA 1OM6A 1C7KA 3KMEA 1D5JA 3ZVSA 1K7IA 1MMRA 1O0QA 4GF1A 5D1SA 3LKAA 1RMZA 1MMBA 1IADA 1JAQA 1GKDA 1IAEA 4JIJA 1HOVA 1XUDA 5I3MA 3GBOA 3UVCA 2MLSA 1ASTA 1GE7A 3LUNA 4PKTA 1BM6A 2EROA 1KAPP 3SHIA 1BSWA 3BA0A 5CUHA 5BOTA 1IABA 2JT6A 1G12A 4GWNA 1AYKA 830CA 1SATA 2W15A 3ZUKA 3NX7A 3HDBA 5D3CA 4DF9A 2JSDA 1C8TA 1XURA 4JPAA 1UMSA 4XM7A 1BUDA 1FLSA 3RTSA 3KHIA 2OVXA 3DTIA 3AIGA 2MZIA 3HB2P 3LJGA 2DW2A 3B92A 1OZ9A 3DTKA 1IAAA 4PKRA 2JNPA 3DPFA 1ZP5A 2OW2A 2KRJA 5LABA 3WV3A 2J83A 1EB6A 1A85A 1JIWP 2CLTA 4DV8A 3K7NA 1QIBA 2E2DA 3HY7A 1OM7A 5I4OA
chains in the Genus database with same CATH topology
3EDIA 2K9CA 1SU3A 1HV5A 4L7AA 1KUKA 4FXYP 2JT5A 1SRPA 3TT4A 1OS2A 4L63A 1R1JA 1XUCA 4FU4A 2DDFA 4GQLA 2YIGA 4WK7A 2O36A 4ON1A 4PKSA 2TCLA 4L19A 1YCMA 1EUBA 1MMQA 1K7QA 2XS3A 4CTHA 1UEAA 4HX3A 4IUWA 3TSKA 5I43A 4H30A 3U1RA 1CGFA 1QJIA 1BKCE 3F17A 1ROSA 2AIGP 2OY4A 2OXZA 1OMJA 2OW9A 3DL1A 1SMPA 4WKIA 4IJOA 1D8FA 4G0DA 3F16A 3ZXHA 2WO8A 2W12A 1JJ9A 1HFSA 3KECA 3OHOA 3KMCA 1GE5A 4H1QA 1CAQA 4R3VA 1PWWA 3F1AA 4I03A 1FBLA 2O3EA 4G9LA 1PWQA 5D1TA 1H71P 3DPEA 4A3WA 2K2GA 2PJTA 3E8RA 3HYGA 1JH1A 3LJZA 1HFCA 1I73A 1QUAA 1CGEA 1BKCA 2V4BA 2X7MA 1YOUA 4DD8A 5JMYA 4PKWA 2FV9A 3LE9A 1ZXVA 1SLNA 4JQGA 2FV5A 2YB9A 2YUFA 3LK8A 1JAOA 4Q1LA 1JIZA 1PWVA 3LMCA 4ZR5A 4H2EA 4JA1A 2USNA 1AF0A 1BQQM 3HY9A 3DSLA 1GE6A 1G05A 2OVZA 4I35A 1WNIA 4WZVA 1JKYA 3LJTA 3RTTA 1XFXA 2OW0A 3OHLA 1R55A 2QPJA 3KWVC 4AIGA 1C3IA 1Y8JA 2Y6DA 3I7GA 2AYKA 1OM8A 4XM8A 2I47A 3VI1A 3V96B 3USNA 1UTZA 4IN9A 1CGLA 3F15A 3KEJA 3HDAP 1BZSA 3EDGA 3AYUA 3Q2HA 4EFSA 1G49A 3EHYA 1PWPA 5CXAA 1EAKA 4PKUA 1D7XA 1KUGA 2WO9A 2X3BA 2L0RA 2WOAA 1JANA 1S4BP 2OZRA 4JP4A 1Z3JA 4GWMA 1GO8P 1XFVA 4WF6A 3EDZA 1QICA 3EDHA 1I1IP 2Y6CA 456CA 1BKCI 1ZS0A 4H84A 4DPEA 3B8ZA 3VTGA 4GR8A 2OI0A 1R54A 2OY2A 2HU6A 3LQ0A 2D1NA 1IAGA 1ZTQA 3I7IA 4H49A 1CK7A 4GR3A 2CKIA 1J7NA 3DNGA 3LQBA 1G9KA 2X3CA 1YQYA 1BIWA 1UTTA 1IACA 3ELMA 1A86A 3L0TA 5B5PA 4XCTA 4HMAA 4J4MA 1ZXCA 1Q3AA 4XBHA 1XFZA 2DDYA 2E3XA 2Z2DA 4AUOA 5D1UA 3HBUP 4FXQA 5CZMA 2X3AA 2RJQA 2MLRA 1UMTA 1GXDA 2SRTA 4H3XA 4A7BA 1R1HA 3DWBA 4H82A 1CIZA 3KEKA 4XM6A 4FVLA 5L79A 1XFUA 3TS4A 1B8YA 1KUHA 1PWUA 3AYKA 1USNA 2DW1A 1ATLA 3Q2GA 2RJPA 2OXWA 2D1OA 1GKCA 1RM8A 3G42A 5I12A 1O0TA 4ILWD 3EHXA 3LGPA 5L7FA 4QKZA 3LIKA 3O2XA 2N8RA 5I0LA 5I2ZA 1JK3A 3G5CA 1KUFA 1DMTA 5D2BA 4GR0A 1MNCA 1SLMA 4L6TA 4PKQA 1KUIA 4PKVA 1FM1A 1XFWA 1JAPA 3K7LA 1BQOA 1HY7A 3B2ZA 3N2VA 2J0TA 1KBCA 1R1IA 3LUMA 1ZVXA 3LEAA 4AXQA 1MMPA 1Y93A 3HBVP 3EWJA 3O64A 2XS4A 3KRYA 1G4KA 1D8MA 5BPAA 1I76A 1YP1A 3WV2A 1QJJA 3DTEA 1AKLA 4AYKA 3P24A 2ERQA 1OS9A 2JIHA 2POJA 3WV1A 1CXVA 1XFYA 3P1VA 4H76A 2ERPA 1B3DA 1DTHA 3TVCA 1ND1A 2OW1A 3L0VA 1CQRA 4GUYA 3F19A 3MA2A 5H8XA 1QIAA 1Y0VA 1L6JA 2MZEA 2W13A 1GO7P 4WKEA 2MZHA 5D7WA 3F18A 966CA 5BOYA 2W14A 1K7GA 5B5OA 1OO9A 2W0DA 2A8HA 3LIRA 2DW0A 1BUVM 1HTDA 3LILA 3CKIA 2OXUA 3N2UA 1OM6A 1C7KA 3KMEA 1D5JA 3ZVSA 1K7IA 1MMRA 1O0QA 4GF1A 5D1SA 3LKAA 1RMZA 1MMBA 1IADA 1JAQA 1GKDA 1IAEA 4JIJA 1HOVA 1XUDA 5I3MA 3GBOA 3UVCA 2MLSA 1ASTA 1GE7A 3LUNA 4PKTA 1BM6A 2EROA 1KAPP 3SHIA 1BSWA 3BA0A 5CUHA 5BOTA 1IABA 2JT6A 1G12A 4GWNA 1AYKA 830CA 1SATA 2W15A 3ZUKA 3NX7A 3HDBA 5D3CA 4DF9A 2JSDA 1C8TA 1XURA 4JPAA 1UMSA 4XM7A 1BUDA 1FLSA 3RTSA 3KHIA 2OVXA 3DTIA 3AIGA 2MZIA 3HB2P 3LJGA 2DW2A 3B92A 3DTKA 1IAAA 4PKRA 2JNPA 3DPFA 1ZP5A 2OW2A 2KRJA 5LABA 3WV3A 2J83A 1EB6A 1A85A 1JIWP 2CLTA 4DV8A 3K7NA 1QIBA 2E2DA 3HY7A 1OM7A 5I4OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EDI A;  2K9C A;  1SU3 A;  1HV5 A;  1KUK A;  4FXY P;  2JT5 A;  1SRP A;  3TT4 A;  1OS2 A;  4L63 A;  1R1J A;  1XUC A;  4FU4 A;  2DDF A;  4GQL A;  2YIG A;  4WK7 A;  2O36 A;  4ON1 A;  4PKS A;  2TCL A;  4L19 A;  1YCM A;  1EUB A;  1MMQ A;  1K7Q A;  2XS3 A;  4CTH A;  1UEA A;  4HX3 A;  4IUW A;  3TSK A;  5I43 A;  4H30 A;  3U1R A;  1CGF A;  1QJI A;  1BKC E;  3F17 A;  1ROS A;  2AIG P;  2OY4 A;  2OXZ A;  1OMJ A;  2OW9 A;  3DL1 A;  1SMP A;  4WKI A;  4IJO A;  1D8F A;  4G0D A;  3F16 A;  3ZXH A;  2WO8 A;  2W12 A;  1JJ9 A;  1HFS A;  3KEC A;  3OHO A;  3KMC A;  1GE5 A;  4H1Q A;  1CAQ A;  4R3V A;  1PWW A;  3F1A A;  4I03 A;  1FBL A;  2O3E A;  4G9L A;  1PWQ A;  5D1T A;  1H71 P;  3DPE A;  4A3W A;  2K2G A;  2PJT A;  3E8R A;  3HYG A;  1JH1 A;  3LJZ A;  1HFC A;  1I73 A;  1QUA A;  1CGE A;  1BKC A;  2V4B A;  2X7M A;  1YOU A;  4DD8 A;  5JMY A;  4PKW A;  2FV9 A;  3LE9 A;  1ZXV A;  1SLN A;  4JQG A;  2FV5 A;  2YB9 A;  3LK8 A;  1JAO A;  4Q1L A;  1JIZ A;  1PWV A;  3LMC A;  4ZR5 A;  4H2E A;  4JA1 A;  2USN A;  1AF0 A;  1BQQ M;  3HY9 A;  3DSL A;  1GE6 A;  1G05 A;  2OVZ A;  4I35 A;  1WNI A;  4WZV A;  1JKY A;  3LJT A;  3RTT A;  1XFX A;  2OW0 A;  3OHL A;  1R55 A;  2QPJ A;  3KWV C;  4AIG A;  1C3I A;  1Y8J A;  2Y6D A;  3I7G A;  2AYK A;  1OM8 A;  4XM8 A;  2I47 A;  3VI1 A;  3V96 B;  3USN A;  1UTZ A;  4IN9 A;  1CGL A;  3F15 A;  3KEJ A;  3HDA P;  1BZS A;  3EDG A;  3AYU A;  3Q2H A;  4EFS A;  1G49 A;  3EHY A;  1PWP A;  5CXA A;  1EAK A;  4PKU A;  1D7X A;  1KUG A;  2WO9 A;  2X3B A;  2L0R A;  2WOA A;  1JAN A;  1S4B P;  2OZR A;  4JP4 A;  1Z3J A;  4GWM A;  1GO8 P;  1XFV A;  4WF6 A;  3EDZ A;  1QIC A;  3EDH A;  1I1I P;  2Y6C A;  456C A;  1BKC I;  1ZS0 A;  4H84 A;  4DPE A;  3B8Z A;  3VTG A;  4GR8 A;  2OI0 A;  1R54 A;  2OY2 A;  2HU6 A;  3LQ0 A;  2D1N A;  1IAG A;  1ZTQ A;  3I7I A;  4H49 A;  1CK7 A;  4GR3 A;  2CKI A;  1J7N A;  3DNG A;  3LQB A;  1G9K A;  2X3C A;  1YQY A;  1BIW A;  1UTT A;  1IAC A;  3ELM A;  1A86 A;  3L0T A;  5B5P A;  4XCT A;  4HMA A;  4J4M A;  1ZXC A;  1Q3A A;  4XBH A;  1XFZ A;  2DDY A;  2E3X A;  2Z2D A;  4AUO A;  5D1U A;  3HBU P;  4FXQ A;  5CZM A;  2X3A A;  2RJQ A;  2MLR A;  1UMT A;  1GXD A;  2SRT A;  4H3X A;  4A7B A;  1R1H A;  3DWB A;  4H82 A;  1CIZ A;  3KEK A;  4XM6 A;  4FVL A;  5L79 A;  1XFU A;  3TS4 A;  1B8Y A;  1KUH A;  1PWU A;  3AYK A;  1USN A;  2DW1 A;  1ATL A;  3Q2G A;  2RJP A;  2OXW A;  2D1O A;  1GKC A;  1RM8 A;  3G42 A;  5I12 A;  1O0T A;  4ILW D;  3EHX A;  3LGP A;  5L7F A;  4QKZ A;  3LIK A;  3O2X A;  2N8R A;  5I0L A;  5I2Z A;  1JK3 A;  3G5C A;  1KUF A;  1DMT A;  5D2B A;  4GR0 A;  1MNC A;  1SLM A;  4L6T A;  4PKQ A;  1KUI A;  4PKV A;  1FM1 A;  1XFW A;  1JAP A;  3K7L A;  1BQO A;  1HY7 A;  3B2Z A;  3N2V A;  2J0T A;  1KBC A;  1R1I A;  3LUM A;  1ZVX A;  3LEA A;  4AXQ A;  1MMP A;  1Y93 A;  3HBV P;  3EWJ A;  3O64 A;  2XS4 A;  3KRY A;  1G4K A;  1D8M A;  5BPA A;  1I76 A;  1YP1 A;  3WV2 A;  1QJJ A;  1AKL A;  4AYK A;  3P24 A;  2ERQ A;  1OS9 A;  2JIH A;  2POJ A;  3WV1 A;  1CXV A;  1XFY A;  3P1V A;  4H76 A;  2ERP A;  1B3D A;  1DTH A;  3TVC A;  1ND1 A;  2OW1 A;  3L0V A;  1CQR A;  4GUY A;  3F19 A;  3MA2 A;  5H8X A;  1QIA A;  1Y0V A;  1L6J A;  2MZE A;  2W13 A;  1GO7 P;  4WKE A;  2MZH A;  5D7W A;  3F18 A;  966C A;  5BOY A;  2W14 A;  1K7G A;  5B5O A;  1OO9 A;  2W0D A;  2A8H A;  3LIR A;  2DW0 A;  1BUV M;  1HTD A;  3LIL A;  3CKI A;  2OXU A;  3N2U A;  1OM6 A;  1C7K A;  3KME A;  1D5J A;  3ZVS A;  1K7I A;  1MMR A;  1O0Q A;  4GF1 A;  5D1S A;  3LKA A;  1RMZ A;  1MMB A;  1IAD A;  1JAQ A;  1GKD A;  1IAE A;  4JIJ A;  1HOV A;  1XUD A;  5I3M A;  3GBO A;  3UVC A;  2MLS A;  1AST A;  1GE7 A;  3LUN A;  4PKT A;  1BM6 A;  2ERO A;  1KAP P;  3SHI A;  1BSW A;  3BA0 A;  5CUH A;  5BOT A;  1IAB A;  2JT6 A;  1G12 A;  4GWN A;  1AYK A;  830C A;  1SAT A;  2W15 A;  3ZUK A;  3NX7 A;  3HDB A;  5D3C A;  4DF9 A;  2JSD A;  1C8T A;  1XUR A;  4JPA A;  1UMS A;  4XM7 A;  1BUD A;  1FLS A;  3RTS A;  3KHI A;  2OVX A;  3AIG A;  2MZI A;  3HB2 P;  3LJG A;  2DW2 A;  3B92 A;  1IAA A;  4PKR A;  2JNP A;  3DPF A;  1ZP5 A;  2OW2 A;  2KRJ A;  5LAB A;  3WV3 A;  2J83 A;  1EB6 A;  1A85 A;  1JIW P;  2CLT A;  4DV8 A;  3K7N A;  1QIB A;  2E2D A;  3HY7 A;  1OM7 A;  5I4O A; 
#chains in the Genus database with same CATH topology
 3EDI A;  2K9C A;  1SU3 A;  1HV5 A;  4L7A A;  1KUK A;  4FXY P;  2JT5 A;  1SRP A;  3TT4 A;  1OS2 A;  4L63 A;  1R1J A;  1XUC A;  4FU4 A;  2DDF A;  4GQL A;  2YIG A;  4WK7 A;  2O36 A;  4ON1 A;  4PKS A;  2TCL A;  4L19 A;  1YCM A;  1EUB A;  1MMQ A;  1K7Q A;  2XS3 A;  4CTH A;  1UEA A;  4HX3 A;  4IUW A;  3TSK A;  5I43 A;  4H30 A;  3U1R A;  1CGF A;  1QJI A;  1BKC E;  3F17 A;  1ROS A;  2AIG P;  2OY4 A;  2OXZ A;  1OMJ A;  2OW9 A;  3DL1 A;  1SMP A;  4WKI A;  4IJO A;  1D8F A;  4G0D A;  3F16 A;  3ZXH A;  2WO8 A;  2W12 A;  1JJ9 A;  1HFS A;  3KEC A;  3OHO A;  3KMC A;  1GE5 A;  4H1Q A;  1CAQ A;  4R3V A;  1PWW A;  3F1A A;  4I03 A;  1FBL A;  2O3E A;  4G9L A;  1PWQ A;  5D1T A;  1H71 P;  3DPE A;  4A3W A;  2K2G A;  2PJT A;  3E8R A;  3HYG A;  1JH1 A;  3LJZ A;  1HFC A;  1I73 A;  1QUA A;  1CGE A;  1BKC A;  2V4B A;  2X7M A;  1YOU A;  4DD8 A;  5JMY A;  4PKW A;  2FV9 A;  3LE9 A;  1ZXV A;  1SLN A;  1XM5 A;  4JQG A;  2FV5 A;  2YB9 A;  2YUF A;  3LK8 A;  1JAO A;  1TVI A;  4Q1L A;  1JIZ A;  1PWV A;  3LMC A;  4ZR5 A;  4H2E A;  4JA1 A;  2USN A;  1AF0 A;  1BQQ M;  3HY9 A;  3DSL A;  1GE6 A;  1G05 A;  2OVZ A;  4I35 A;  1WNI A;  4WZV A;  1JKY A;  3LJT A;  3RTT A;  1XFX A;  2OW0 A;  3OHL A;  1R55 A;  2QPJ A;  3KWV C;  4AIG A;  1C3I A;  1Y8J A;  2Y6D A;  3I7G A;  2AYK A;  1OM8 A;  4XM8 A;  2I47 A;  3VI1 A;  3V96 B;  3USN A;  1UTZ A;  4IN9 A;  1CGL A;  3F15 A;  3KEJ A;  3HDA P;  1BZS A;  3EDG A;  3AYU A;  3Q2H A;  4EFS A;  1G49 A;  3EHY A;  1PWP A;  5CXA A;  1EAK A;  4PKU A;  1D7X A;  1KUG A;  2WO9 A;  2X3B A;  2L0R A;  2WOA A;  1JAN A;  1S4B P;  2OZR A;  4JP4 A;  1Z3J A;  4GWM A;  1GO8 P;  1XFV A;  4WF6 A;  3EDZ A;  1QIC A;  3EDH A;  1I1I P;  2Y6C A;  456C A;  1BKC I;  1ZS0 A;  4H84 A;  4DPE A;  3B8Z A;  3VTG A;  4GR8 A;  2OI0 A;  1R54 A;  2OY2 A;  2HU6 A;  3LQ0 A;  2D1N A;  1IAG A;  1ZTQ A;  3I7I A;  4H49 A;  1CK7 A;  4GR3 A;  2CKI A;  1J7N A;  3DNG A;  3LQB A;  1G9K A;  2X3C A;  1YQY A;  1BIW A;  1UTT A;  1IAC A;  3ELM A;  1A86 A;  3L0T A;  5B5P A;  4XCT A;  4HMA A;  4J4M A;  1ZXC A;  1Q3A A;  4XBH A;  1XFZ A;  2DDY A;  2E3X A;  2Z2D A;  4AUO A;  5D1U A;  3HBU P;  4FXQ A;  5CZM A;  2X3A A;  2RJQ A;  2MLR A;  1UMT A;  1GXD A;  2SRT A;  4H3X A;  4A7B A;  1R1H A;  3DWB A;  4H82 A;  1CIZ A;  3KEK A;  4XM6 A;  4FVL A;  5L79 A;  1XFU A;  3TS4 A;  1B8Y A;  1KUH A;  1PWU A;  3AYK A;  1USN A;  2DW1 A;  1ATL A;  3Q2G A;  2RJP A;  2OXW A;  2D1O A;  1GKC A;  1RM8 A;  3G42 A;  5I12 A;  1O0T A;  4ILW D;  3EHX A;  3LGP A;  5L7F A;  4QKZ A;  3LIK A;  3O2X A;  2N8R A;  5I0L A;  5I2Z A;  1JK3 A;  3G5C A;  1KUF A;  1DMT A;  5D2B A;  4GR0 A;  1MNC A;  1SLM A;  4L6T A;  4PKQ A;  1KUI A;  4PKV A;  1FM1 A;  1XFW A;  1JAP A;  3K7L A;  1BQO A;  1HY7 A;  3B2Z A;  3N2V A;  2J0T A;  1KBC A;  1R1I A;  3LUM A;  1ZVX A;  3LEA A;  4AXQ A;  1MMP A;  1Y93 A;  3HBV P;  3EWJ A;  3O64 A;  2XS4 A;  3KRY A;  1G4K A;  1D8M A;  5BPA A;  1I76 A;  1YP1 A;  3WV2 A;  1QJJ A;  3DTE A;  1AKL A;  4AYK A;  3P24 A;  2ERQ A;  1OS9 A;  2JIH A;  2POJ A;  3WV1 A;  1CXV A;  1XFY A;  3P1V A;  4H76 A;  2ERP A;  1B3D A;  1DTH A;  3TVC A;  1ND1 A;  2OW1 A;  3L0V A;  1CQR A;  4GUY A;  3F19 A;  3MA2 A;  5H8X A;  1QIA A;  1Y0V A;  1L6J A;  2MZE A;  2W13 A;  1GO7 P;  4WKE A;  2MZH A;  5D7W A;  3F18 A;  966C A;  5BOY A;  2W14 A;  1K7G A;  5B5O A;  1XAX A;  1OO9 A;  2W0D A;  2A8H A;  3LIR A;  2DW0 A;  1BUV M;  1HTD A;  3LIL A;  3CKI A;  2OXU A;  3N2U A;  1OM6 A;  1C7K A;  3KME A;  1D5J A;  3ZVS A;  1K7I A;  1MMR A;  1O0Q A;  4GF1 A;  5D1S A;  3LKA A;  1RMZ A;  1MMB A;  1IAD A;  1JAQ A;  1GKD A;  1IAE A;  4JIJ A;  1HOV A;  1XUD A;  5I3M A;  3GBO A;  3UVC A;  2MLS A;  1AST A;  1GE7 A;  3LUN A;  4PKT A;  1BM6 A;  2ERO A;  1KAP P;  3SHI A;  1BSW A;  3BA0 A;  5CUH A;  5BOT A;  1IAB A;  2JT6 A;  1G12 A;  4GWN A;  1AYK A;  830C A;  1SAT A;  2W15 A;  3ZUK A;  3NX7 A;  3HDB A;  5D3C A;  4DF9 A;  2JSD A;  1C8T A;  1XUR A;  4JPA A;  1UMS A;  4XM7 A;  1BUD A;  1FLS A;  3RTS A;  3KHI A;  2OVX A;  3DTI A;  3AIG A;  2MZI A;  3HB2 P;  3LJG A;  2DW2 A;  3B92 A;  1OZ9 A;  3DTK A;  1IAA A;  4PKR A;  2JNP A;  3DPF A;  1ZP5 A;  2OW2 A;  2KRJ A;  5LAB A;  3WV3 A;  2J83 A;  1EB6 A;  1A85 A;  1JIW P;  2CLT A;  4DV8 A;  3K7N A;  1QIB A;  2E2D A;  3HY7 A;  1OM7 A;  5I4O A; 
#chains in the Genus database with same CATH homology
 3EDI A;  2K9C A;  1SU3 A;  1HV5 A;  4L7A A;  1KUK A;  4FXY P;  2JT5 A;  1SRP A;  3TT4 A;  1OS2 A;  4L63 A;  1R1J A;  1XUC A;  4FU4 A;  2DDF A;  4GQL A;  2YIG A;  4WK7 A;  2O36 A;  4ON1 A;  4PKS A;  2TCL A;  4L19 A;  1YCM A;  1EUB A;  1MMQ A;  1K7Q A;  2XS3 A;  4CTH A;  1UEA A;  4HX3 A;  4IUW A;  3TSK A;  5I43 A;  4H30 A;  3U1R A;  1CGF A;  1QJI A;  1BKC E;  3F17 A;  1ROS A;  2AIG P;  2OY4 A;  2OXZ A;  1OMJ A;  2OW9 A;  3DL1 A;  1SMP A;  4WKI A;  4IJO A;  1D8F A;  4G0D A;  3F16 A;  3ZXH A;  2WO8 A;  2W12 A;  1JJ9 A;  1HFS A;  3KEC A;  3OHO A;  3KMC A;  1GE5 A;  4H1Q A;  1CAQ A;  4R3V A;  1PWW A;  3F1A A;  4I03 A;  1FBL A;  2O3E A;  4G9L A;  1PWQ A;  5D1T A;  1H71 P;  3DPE A;  4A3W A;  2K2G A;  2PJT A;  3E8R A;  3HYG A;  1JH1 A;  3LJZ A;  1HFC A;  1I73 A;  1QUA A;  1CGE A;  1BKC A;  2V4B A;  2X7M A;  1YOU A;  4DD8 A;  5JMY A;  4PKW A;  2FV9 A;  3LE9 A;  1ZXV A;  1SLN A;  4JQG A;  2FV5 A;  2YB9 A;  2YUF A;  3LK8 A;  1JAO A;  4Q1L A;  1JIZ A;  1PWV A;  3LMC A;  4ZR5 A;  4H2E A;  4JA1 A;  2USN A;  1AF0 A;  1BQQ M;  3HY9 A;  3DSL A;  1GE6 A;  1G05 A;  2OVZ A;  4I35 A;  1WNI A;  4WZV A;  1JKY A;  3LJT A;  3RTT A;  1XFX A;  2OW0 A;  3OHL A;  1R55 A;  2QPJ A;  3KWV C;  4AIG A;  1C3I A;  1Y8J A;  2Y6D A;  3I7G A;  2AYK A;  1OM8 A;  4XM8 A;  2I47 A;  3VI1 A;  3V96 B;  3USN A;  1UTZ A;  4IN9 A;  1CGL A;  3F15 A;  3KEJ A;  3HDA P;  1BZS A;  3EDG A;  3AYU A;  3Q2H A;  4EFS A;  1G49 A;  3EHY A;  1PWP A;  5CXA A;  1EAK A;  4PKU A;  1D7X A;  1KUG A;  2WO9 A;  2X3B A;  2L0R A;  2WOA A;  1JAN A;  1S4B P;  2OZR A;  4JP4 A;  1Z3J A;  4GWM A;  1GO8 P;  1XFV A;  4WF6 A;  3EDZ A;  1QIC A;  3EDH A;  1I1I P;  2Y6C A;  456C A;  1BKC I;  1ZS0 A;  4H84 A;  4DPE A;  3B8Z A;  3VTG A;  4GR8 A;  2OI0 A;  1R54 A;  2OY2 A;  2HU6 A;  3LQ0 A;  2D1N A;  1IAG A;  1ZTQ A;  3I7I A;  4H49 A;  1CK7 A;  4GR3 A;  2CKI A;  1J7N A;  3DNG A;  3LQB A;  1G9K A;  2X3C A;  1YQY A;  1BIW A;  1UTT A;  1IAC A;  3ELM A;  1A86 A;  3L0T A;  5B5P A;  4XCT A;  4HMA A;  4J4M A;  1ZXC A;  1Q3A A;  4XBH A;  1XFZ A;  2DDY A;  2E3X A;  2Z2D A;  4AUO A;  5D1U A;  3HBU P;  4FXQ A;  5CZM A;  2X3A A;  2RJQ A;  2MLR A;  1UMT A;  1GXD A;  2SRT A;  4H3X A;  4A7B A;  1R1H A;  3DWB A;  4H82 A;  1CIZ A;  3KEK A;  4XM6 A;  4FVL A;  5L79 A;  1XFU A;  3TS4 A;  1B8Y A;  1KUH A;  1PWU A;  3AYK A;  1USN A;  2DW1 A;  1ATL A;  3Q2G A;  2RJP A;  2OXW A;  2D1O A;  1GKC A;  1RM8 A;  3G42 A;  5I12 A;  1O0T A;  4ILW D;  3EHX A;  3LGP A;  5L7F A;  4QKZ A;  3LIK A;  3O2X A;  2N8R A;  5I0L A;  5I2Z A;  1JK3 A;  3G5C A;  1KUF A;  1DMT A;  5D2B A;  4GR0 A;  1MNC A;  1SLM A;  4L6T A;  4PKQ A;  1KUI A;  4PKV A;  1FM1 A;  1XFW A;  1JAP A;  3K7L A;  1BQO A;  1HY7 A;  3B2Z A;  3N2V A;  2J0T A;  1KBC A;  1R1I A;  3LUM A;  1ZVX A;  3LEA A;  4AXQ A;  1MMP A;  1Y93 A;  3HBV P;  3EWJ A;  3O64 A;  2XS4 A;  3KRY A;  1G4K A;  1D8M A;  5BPA A;  1I76 A;  1YP1 A;  3WV2 A;  1QJJ A;  3DTE A;  1AKL A;  4AYK A;  3P24 A;  2ERQ A;  1OS9 A;  2JIH A;  2POJ A;  3WV1 A;  1CXV A;  1XFY A;  3P1V A;  4H76 A;  2ERP A;  1B3D A;  1DTH A;  3TVC A;  1ND1 A;  2OW1 A;  3L0V A;  1CQR A;  4GUY A;  3F19 A;  3MA2 A;  5H8X A;  1QIA A;  1Y0V A;  1L6J A;  2MZE A;  2W13 A;  1GO7 P;  4WKE A;  2MZH A;  5D7W A;  3F18 A;  966C A;  5BOY A;  2W14 A;  1K7G A;  5B5O A;  1OO9 A;  2W0D A;  2A8H A;  3LIR A;  2DW0 A;  1BUV M;  1HTD A;  3LIL A;  3CKI A;  2OXU A;  3N2U A;  1OM6 A;  1C7K A;  3KME A;  1D5J A;  3ZVS A;  1K7I A;  1MMR A;  1O0Q A;  4GF1 A;  5D1S A;  3LKA A;  1RMZ A;  1MMB A;  1IAD A;  1JAQ A;  1GKD A;  1IAE A;  4JIJ A;  1HOV A;  1XUD A;  5I3M A;  3GBO A;  3UVC A;  2MLS A;  1AST A;  1GE7 A;  3LUN A;  4PKT A;  1BM6 A;  2ERO A;  1KAP P;  3SHI A;  1BSW A;  3BA0 A;  5CUH A;  5BOT A;  1IAB A;  2JT6 A;  1G12 A;  4GWN A;  1AYK A;  830C A;  1SAT A;  2W15 A;  3ZUK A;  3NX7 A;  3HDB A;  5D3C A;  4DF9 A;  2JSD A;  1C8T A;  1XUR A;  4JPA A;  1UMS A;  4XM7 A;  1BUD A;  1FLS A;  3RTS A;  3KHI A;  2OVX A;  3DTI A;  3AIG A;  2MZI A;  3HB2 P;  3LJG A;  2DW2 A;  3B92 A;  3DTK A;  1IAA A;  4PKR A;  2JNP A;  3DPF A;  1ZP5 A;  2OW2 A;  2KRJ A;  5LAB A;  3WV3 A;  2J83 A;  1EB6 A;  1A85 A;  1JIW P;  2CLT A;  4DV8 A;  3K7N A;  1QIB A;  2E2D A;  3HY7 A;  1OM7 A;  5I4O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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