1G1FA

Crystal structure of protein tyrosine phosphatase 1b complexed with a tri-phosphorylated peptide (rdi(ptr)etd(ptr)(ptr)rk) from the insulin receptor kinase
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHASAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
pubmed doi rcsb
molecule keywords PROTEIN TYROSINE PHOSPHATASE 1B
molecule tags Hydrolase, signaling protein
source organism Homo sapiens
total genus 98
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1g1fA00
3I36A 2IMGA 2H4KA 3D1HA 1PTUA 3V0IA 4GRZA 4RHGA 1ONYA 3ZM2A 1G4WR 4QAHA 4GFVA 5EHPA 5KA4A 3ZM1A 1U24A 1YWFA 1OEUA 4HRFA 2C7SA 2CM3A 4ERCA 1OHDA 2CM8A 2BGEA 4DGXA 1C85A 5GTJA 1Q6MA 2P6XA 5J8RA 2H4VA 3RO1A 5LXQB 3BM8A 3GXGA 2J16B 3QCLA 3V0JA 3EU0A 4J51A 4H34A 1T49A 3EZZA 2QCJA 4WTYA 1ONZA 4KYRA 3MOWA 2NZ6A 1NZ7A 1YFOA 2CMBA 2NV5A 3O4TA 4GRYA 1PTTA 2ZMMA 1QZ0A 1XXPA 3V0GA 1G1HA 4WU2A 1WRMA 2H4GA 2NT2A 5KA7A 4HJQA 5KABA 3PS5A 5MMZB 3QCGA 4RDDA 4D3RA 1D5RA 1NWEA 1PTYA 4JMJA 5IBMA 2B07A 1C86A 2H03A 3S3HA 1XXVA 1L8GA 2G59A 2I6IA 5BX1A 1LYVA 2P4DA 4NX8A 3V0FA 3QCDA 5AWXA 2GJTA 3I7ZA 2I1YA 1OEVA 2I4HA 4QBWA 3OMHA 2I3RA 3V0EA 2I42A 2GP0A 2E0TA 2BIJA 1G1FA 3F9AA 1RPMA 2HB1A 4R0SA 2B49A 2B4SA 2CM2A 2QDPA 3BRHA 1C88A 4GE2A 1G1GA 2DXPA 3QCMA 4NYHA 4RI4A 1G4US 2I6OA 1JLNA 3D9CA 1G7FA 1PTVA 1LQFA 3NMEA 3QKQA 3MMJA 1GWZA 4YAAA 2PSZA 1EENA 2C46A 4BJOA 2NT7A 1OHEA 3H2XA 2MBCA 2YDUA 3S3EA 4D3QA 2R0BA 4PVGA 1YGUA 5K9WA 3BLTA 1ZC0A 2I6MA 4GS0A 2VEWA 1NO6A 4JBCA 2BV5A 4D3PA 1NWLA 1I57A 1ZCLA 2H04A 1C83A 1PA9A 4JNBA 2H02A 5KADA 1OESA 2B3OA 1PYNA 3QCNA 5KA0A 5K9VA 3GXHA 2Y96A 4ZI4A 3EB1A 2QEPA 4ICZA 1A5YA 2CNFA 1SUGA 1YGRA 4ZRTA 5HDEA 1KAVA 2PA5A 4HJPA 2CNGA 3B7OA 2VEUA 2RF6A 1BZJA 2CNHA 2PQ5A 3EMUA 3ZMPA 3S3FA 1G7GA 3RGQA 4OHHA 3S3KA 2HC1A 1Q1MA 4S0GA 3QKPA 1EEOA 1OEOX 2HC2A 2QBRA 4QUMA 1YTNA 4Y14A 1NNYA 4B04A 2VEXA 5KACA 2ESBA 4NNDA 2SHPA 2G6ZA 1NL9A 2Y2FA 5K24A 1RXDA 1XM2A 3O4SA 2I4GA 3BLUA 1WAXA 2M3VA 1YZ4A 1U26A 1M3GA 3LJ8A 2I6PA 2J16A 1FPRA 2F70A 3D44A 2FH7A 1BZHA 2ZN7A 2F6YA 3MOZA 2CNEA 1I9SA 3V0DA 1VHRA 1YN9A 3O5XA 2BZLA 5M43A 3F41A 3ZV2A 5KA3A 2HCMA 3F99A 4RI5A 2QBPA 2I4EA 5IBSA 2F71A 4Y2EA 3AWFA 3QCJA 1MKPA 1T48A 2AZRA 2NLKA 2A8BA 3U96A 2QBSA 3I80A 3QCBA 3RGOA 1OHCA 1Q6SA 3A5JA 1P15A 4YR8B 5K25A 2F6VA 1L8KA 1X24A 5EHRA 2QDCA 3AWGA 5KA1A 1Q6JA 1XBOA 2B4PA 1I9TA 5KA2A 2I6JA 4OHIA 2OC3A 3ZM3A 2VEYA 1C84A 4GFUA 2CMAA 1JF7A 3N0AA 3D42A 3F9BA 1OEMX 3QCKA 2B4OA 4WOHA 2OZ5A 1AAXA 4I8NA 4IKCA 2AHSA 4BPCA 1PXHA 4OHDA 2NTAA 4QBEA 2JJDA 1XRIA 2Q05A 3QCCA 2F46A 2VEVA 4NWFA 2OOQA 4MBBA 2FJNA 4RH9A 2HY3A 5K22A 4OHEA 3S4EA 4ZN5A 1BZCA 2F6TA 2F6ZA 1ZZWA 2PI7A 4R0TA 4RKKA 2I5XA 1FPZA 3SMEA 3O4UA 2HNQA 3S4OA 3QCIA 2CNIA 3A5KA 1Q6TA 2CJZA 4DGPA 2WGPA 1YTSA 2J17A 1R6HA 2QDMA 1GFYA 4NWGA 1FQ1A 4TVVA 3EAXA 5BZZA 4R30A 5BUGA 3CWEA 2CFVA 3D1OA 4H1OA 1YTWA 5I6VA 3D1QA 4GWFA 2F6WA 4JMKA 1YPTA 4KYQA 1QXKA 1ECVA 3AWEA 3QCHA 2BGDA 1ZCKA 3QCEA 4OHLA 2I75A 3ZMQA 2A3KA 3O3LA 4KI9A 4QUNA 2CM7A 1PH0A 3V0HA 2B4UA 5KA8A 4GE5A 1J4XA 1OETA 2QBQA 4RH5A 2PBNA 2I3UA 3QCFA 2HVLA 3ZM0A 3F81A 1LARA 2FJMA 1WCHA 2QCTA 2GWOA 2Q47A 5BZXA 5KA9A 3OLRA 2PT0A 5KAAA 4PYHA 2F6FA 2OUDA 1Q6PA 1KAKA 1C87A 3SR9A 4GE6A 3RZ2A 5K23A 3M4UA 1PA1A 3CM3A 4AZ1A 1T4JA 2CMCA 4WU3A 1V3AA 2HNPA 4QAPA 1Q6NA 1U25A 4Z6BA 2HXPA
chains in the Genus database with same CATH superfamily
2XPCA 3I36A 2IMGA 2H4KA 1GG4A 3D1HA 1PTUA 2Y67A 3V0IA 4GRZA 2AM2A 3UAGA 4RHGA 1ONYA 3ZM2A 1G4WR 4QAHA 4GFVA 4UAGA 5EHPA 5KA4A 3ZM1A 1U24A 1YWFA 1OEUA 4HRFA 2C7SA 2CM3A 4ERCA 1OHDA 2CM8A 2BGEA 4DGXA 1C85A 5GTJA 1Q6MA 2P6XA 2Y66A 5J8RA 2H4VA 3RO1A 5LXQB 3BM8A 3GXGA 2J16B 3QCLA 3V0JA 3EU0A 3PYZA 4J51A 4H34A 1T49A 3EZZA 3NRSA 1W7KA 2QCJA 4WTYA 1ONZA 4KYRA 3MOWA 2NZ6A 1NZ7A 1YFOA 2CMBA 2NV5A 5A5FA 3O4TA 4GRYA 1FGSA 1UAGA 1PTTA 2ZMMA 1QZ0A 1GQQA 1XXPA 3V0GA 1G1HA 4WU2A 1WRMA 2H4GA 2NT2A 5KA7A 4HJQA 5KABA 2AM1A 3PS5A 5MMZB 2WJPA 3QCGA 4RDDA 3ZL8A 4D3RA 1D5RA 1NWEA 1PTYA 4JMJA 5IBMA 2B07A 1C86A 2H03A 3S3HA 1XXVA 1L8GA 2G59A 2I6IA 5BX1A 1LYVA 2P4DA 4BUCA 4NX8A 3V0FA 3QCDA 5AWXA 2GJTA 3I7ZA 2I1YA 1OEVA 2I4HA 4QBWA 3OMHA 2I3RA 3V0EA 2I42A 2GP0A 2E0TA 2BIJA 1G1FA 1RPMA 2HB1A 3F9AA 4R0SA 2B49A 2B4SA 2CM2A 2QDPA 3BRHA 1C88A 4GE2A 1G1GA 2DXPA 3QCMA 4NYHA 2VTDA 4RI4A 1G4US 2UUOA 2I6OA 1JLNA 3D9CA 1G7FA 1PTVA 1LQFA 4CVMA 3NMEA 2JFFA 3QKQA 3MMJA 1GWZA 4YAAA 2PSZA 1EENA 2C46A 4BJOA 2NT7A 4BUBA 1OHEA 3H2XA 2MBCA 2YDUA 3S3EA 4D3QA 2R0BA 4PVGA 1YGUA 5K9WA 3BLTA 1ZC0A 2I6MA 2GCBA 4GS0A 2VEWA 1NO6A 4JBCA 2BV5A 4D3PA 1E0DA 1NWLA 1I57A 1ZCLA 2GCAA 2H04A 1C83A 1PA9A 4JNBA 2H02A 5KADA 1OESA 2B3OA 1PYNA 3QCNA 5KA0A 5K9VA 3GXHA 2Y96A 4ZI4A 3EB1A 2QEPA 4ICZA 1A5YA 2CNFA 1SUGA 1YGRA 4ZRTA 5HDEA 1KAVA 2PA5A 4HJPA 2CNGA 3B7OA 2VEUA 2RF6A 1BZJA 2CNHA 2PQ5A 3EMUA 3HN7A 5A5EA 1P3DA 3ZMPA 3S3FA 1G7GA 3RGQA 2GC6A 1EEHA 4OHHA 3S3KA 2HC1A 1Q1MA 4S0GA 3QKPA 1EEOA 1OEOX 2HC2A 2QBRA 4QUMA 1YTNA 4Y14A 1NNYA 4B04A 1JBWA 2VEXA 5KACA 2ESBA 4NNDA 2SHPA 2G6ZA 1NL9A 2Y2FA 5K24A 1RXDA 1XM2A 3O4SA 2I4GA 2JFHA 3BLUA 1WAXA 2M3VA 1YZ4A 4HV4A 1U26A 1M3GA 3LJ8A 3LK7A 2I6PA 2UUPA 2J16A 1FPRA 2F70A 3D44A 2FH7A 1BZHA 2ZN7A 2F6YA 2UAGA 3MOZA 2XJAA 4CVLA 2CNEA 1P31A 1I9SA 3V0DA 1VHRA 1YN9A 3O5XA 2BZLA 5M43A 3F41A 2Y1OA 3ZV2A 5KA3A 2HCMA 3F99A 4RI5A 2QBPA 2I4EA 5IBSA 2F71A 4Y2EA 3AWFA 3QCJA 1MKPA 1T48A 2AZRA 2NLKA 2A8BA 3U96A 2QBSA 3I80A 3QCBA 3RGOA 1OHCA 1Q6SA 3A5JA 1P15A 4YR8B 5K25A 2F6VA 1L8KA 1X24A 5EHRA 2QDCA 3AWGA 5KA1A 1Q6JA 2VOSA 1XBOA 2B4PA 1I9TA 5KA2A 2I6JA 4OHIA 2OC3A 3ZM3A 2VEYA 1C84A 4GFUA 2CMAA 1JF7A 3N0AA 3D42A 3F9BA 1OEMX 3QCKA 2B4OA 4WOHA 2OZ5A 1AAXA 2X5OA 4I8NA 4IKCA 2AHSA 4BPCA 2Y68A 1PXHA 4OHDA 2NTAA 4QBEA 2JJDA 1XRIA 2VORA 2Q05A 3QCCA 1E8CA 2F46A 2VEVA 4NWFA 2OOQA 4MBBA 2FJNA 4RH9A 2HY3A 5K22A 4OHEA 3S4EA 4ZN5A 1BZCA 2F6TA 2F6ZA 1ZZWA 2PI7A 4R0TA 4RKKA 1W78A 2I5XA 1FPZA 3SMEA 3O4UA 2HNQA 3S4OA 3QCIA 2CNIA 3A5KA 1Q6TA 3ZM5A 2CJZA 4DGPA 2WGPA 1YTSA 2J17A 1R6HA 2QDMA 1GFYA 4NWGA 1FQ1A 4TVVA 3EAXA 5BZZA 4R30A 5BUGA 3CWEA 2CFVA 3D1OA 4H1OA 1YTWA 4C13A 5I6VA 1JBVA 3ZM6A 3D1QA 4GWFA 2F6WA 4JMKA 1YPTA 4KYQA 1QXKA 1ECVA 3AWEA 3QCHA 3QCZA 2BGDA 1ZCKA 3QCEA 4OHLA 2I75A 3ZMQA 2A3KA 3O3LA 4QDIA 4KI9A 4QUNA 2CM7A 1PH0A 3V0HA 2B4UA 5KA8A 3N2AA 4GE5A 2F00A 1O5ZA 1J4XA 1OETA 2QBQA 4RH5A 2PBNA 3MVNA 2I3UA 3QCFA 2HVLA 3ZM0A 3F81A 1LARA 2VTEA 2FJMA 1WCHA 2GC5A 2QCTA 2GWOA 2Q47A 5BZXA 5KA9A 1GQYA 3OLRA 4CVKA 4C12A 2PT0A 5KAAA 4PYHA 2F6FA 2OUDA 1Q6PA 4ZIYA 4QF5A 1KAKA 1C87A 2WTZA 3SR9A 4GE6A 3RZ2A 5K23A 3M4UA 1PA1A 3CM3A 4AZ1A 1T4JA 2CMCA 1J6UA 4WU3A 2JFGA 1V3AA 2HNPA 4QAPA 1Q6NA 1U25A 4Z6BA 2HXPA
chains in the Genus database with same CATH topology
3I36A 2IMGA 2H4KA 3D1HA 1PTUA 3V0IA 4GRZA 4RHGA 1ONYA 3ZM2A 1G4WR 4QAHA 4GFVA 5EHPA 5KA4A 3ZM1A 1U24A 1YWFA 1OEUA 4HRFA 2C7SA 2CM3A 4ERCA 1OHDA 2CM8A 2BGEA 4DGXA 1C85A 5GTJA 1Q6MA 2P6XA 5J8RA 2H4VA 3RO1A 5LXQB 3BM8A 3GXGA 2J16B 3QCLA 3V0JA 3EU0A 4J51A 4H34A 1T49A 3EZZA 2QCJA 4WTYA 1ONZA 4KYRA 3MOWA 2NZ6A 1NZ7A 1YFOA 2CMBA 2NV5A 3O4TA 4GRYA 1PTTA 2ZMMA 1QZ0A 1XXPA 3V0GA 1G1HA 4WU2A 1WRMA 2H4GA 2NT2A 5KA7A 4HJQA 5KABA 3PS5A 5MMZB 3QCGA 4RDDA 4D3RA 1D5RA 1NWEA 1PTYA 4JMJA 5IBMA 2B07A 1C86A 2H03A 3S3HA 1XXVA 1L8GA 2G59A 2I6IA 5BX1A 1LYVA 2P4DA 4NX8A 3V0FA 3QCDA 5AWXA 2GJTA 3I7ZA 2I1YA 1OEVA 2I4HA 4QBWA 3OMHA 2I3RA 3V0EA 2I42A 2GP0A 2E0TA 2BIJA 1G1FA 3F9AA 1RPMA 2HB1A 4R0SA 2B49A 2B4SA 2CM2A 2QDPA 3BRHA 1C88A 4GE2A 1G1GA 2DXPA 3QCMA 4NYHA 4RI4A 1G4US 2I6OA 1JLNA 3D9CA 1G7FA 1PTVA 1LQFA 3NMEA 3QKQA 3MMJA 1GWZA 4YAAA 2PSZA 1EENA 2C46A 4BJOA 2NT7A 1OHEA 3H2XA 2MBCA 2YDUA 3S3EA 4D3QA 2R0BA 4PVGA 1YGUA 5K9WA 3BLTA 1ZC0A 2I6MA 4GS0A 2VEWA 1NO6A 4JBCA 2BV5A 4D3PA 1NWLA 1I57A 1ZCLA 2H04A 1C83A 1PA9A 4JNBA 2H02A 5KADA 1OESA 2B3OA 1PYNA 3QCNA 5KA0A 5K9VA 3GXHA 2Y96A 4ZI4A 3EB1A 2QEPA 4ICZA 1A5YA 2CNFA 1SUGA 1YGRA 4ZRTA 5HDEA 1KAVA 2PA5A 4HJPA 2CNGA 3B7OA 2VEUA 2RF6A 1BZJA 2CNHA 2PQ5A 3EMUA 3ZMPA 3S3FA 1G7GA 3RGQA 4OHHA 3S3KA 2HC1A 1Q1MA 4S0GA 3QKPA 1EEOA 1OEOX 2HC2A 2QBRA 4QUMA 1YTNA 4Y14A 1NNYA 4B04A 2VEXA 5KACA 2ESBA 4NNDA 2SHPA 2G6ZA 1NL9A 2Y2FA 5K24A 1RXDA 1XM2A 3O4SA 2I4GA 3BLUA 1WAXA 2M3VA 1YZ4A 1U26A 1M3GA 3LJ8A 2I6PA 2J16A 1FPRA 2F70A 3D44A 2FH7A 1BZHA 2ZN7A 2F6YA 3MOZA 2CNEA 1I9SA 3V0DA 1VHRA 1YN9A 3O5XA 2BZLA 5M43A 3F41A 3ZV2A 5KA3A 2HCMA 3F99A 4RI5A 2QBPA 2I4EA 5IBSA 2F71A 4Y2EA 3AWFA 3QCJA 1MKPA 1T48A 2AZRA 2NLKA 2A8BA 3U96A 2QBSA 3I80A 3QCBA 3RGOA 1OHCA 1Q6SA 3A5JA 1P15A 4YR8B 5K25A 2F6VA 1L8KA 1X24A 5EHRA 2QDCA 3AWGA 5KA1A 1Q6JA 1XBOA 2B4PA 1I9TA 5KA2A 2I6JA 4OHIA 2OC3A 3ZM3A 2VEYA 1C84A 4GFUA 2CMAA 1JF7A 3N0AA 3D42A 3F9BA 1OEMX 3QCKA 2B4OA 4WOHA 2OZ5A 1AAXA 4I8NA 4IKCA 2AHSA 4BPCA 1PXHA 4OHDA 2NTAA 4QBEA 2JJDA 1XRIA 2Q05A 3QCCA 2F46A 2VEVA 4NWFA 2OOQA 4MBBA 2FJNA 4RH9A 2HY3A 5K22A 4OHEA 3S4EA 4ZN5A 1BZCA 2F6TA 2F6ZA 1ZZWA 2PI7A 4R0TA 4RKKA 2I5XA 1FPZA 3SMEA 3O4UA 2HNQA 3S4OA 3QCIA 2CNIA 3A5KA 1Q6TA 2CJZA 4DGPA 2WGPA 1YTSA 2J17A 1R6HA 2QDMA 1GFYA 4NWGA 1FQ1A 4TVVA 3EAXA 5BZZA 4R30A 5BUGA 3CWEA 2CFVA 3D1OA 4H1OA 1YTWA 5I6VA 3D1QA 4GWFA 2F6WA 4JMKA 1YPTA 4KYQA 1QXKA 1ECVA 3AWEA 3QCHA 2BGDA 1ZCKA 3QCEA 4OHLA 2I75A 3ZMQA 2A3KA 3O3LA 4KI9A 4QUNA 2CM7A 1PH0A 3V0HA 2B4UA 5KA8A 4GE5A 1J4XA 1OETA 2QBQA 4RH5A 2PBNA 2I3UA 3QCFA 2HVLA 3ZM0A 3F81A 1LARA 2FJMA 1WCHA 2QCTA 2GWOA 2Q47A 5BZXA 5KA9A 3OLRA 2PT0A 5KAAA 4PYHA 2F6FA 2OUDA 1Q6PA 1KAKA 1C87A 3SR9A 4GE6A 3RZ2A 5K23A 3M4UA 1PA1A 3CM3A 4AZ1A 1T4JA 2CMCA 4WU3A 1V3AA 2HNPA 4QAPA 1Q6NA 1U25A 4Z6BA 2HXPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I36 A;  2IMG A;  2H4K A;  3D1H A;  1PTU A;  3V0I A;  4GRZ A;  4RHG A;  1ONY A;  3ZM2 A;  1G4W R;  4QAH A;  4GFV A;  5EHP A;  5KA4 A;  3ZM1 A;  1U24 A;  1YWF A;  1OEU A;  4HRF A;  2C7S A;  2CM3 A;  4ERC A;  1OHD A;  2CM8 A;  2BGE A;  4DGX A;  1C85 A;  5GTJ A;  1Q6M A;  2P6X A;  5J8R A;  2H4V A;  3RO1 A;  5LXQ B;  3BM8 A;  3GXG A;  2J16 B;  3QCL A;  3V0J A;  3EU0 A;  4J51 A;  4H34 A;  1T49 A;  3EZZ A;  2QCJ A;  4WTY A;  1ONZ A;  4KYR A;  3MOW A;  2NZ6 A;  1NZ7 A;  1YFO A;  2CMB A;  2NV5 A;  3O4T A;  4GRY A;  1PTT A;  2ZMM A;  1QZ0 A;  1XXP A;  3V0G A;  1G1H A;  4WU2 A;  1WRM A;  2H4G A;  2NT2 A;  5KA7 A;  4HJQ A;  5KAB A;  3PS5 A;  5MMZ B;  3QCG A;  4RDD A;  4D3R A;  1D5R A;  1NWE A;  1PTY A;  4JMJ A;  5IBM A;  2B07 A;  1C86 A;  2H03 A;  3S3H A;  1XXV A;  1L8G A;  2G59 A;  2I6I A;  5BX1 A;  1LYV A;  2P4D A;  4NX8 A;  3V0F A;  3QCD A;  5AWX A;  2GJT A;  3I7Z A;  2I1Y A;  1OEV A;  2I4H A;  4QBW A;  3OMH A;  2I3R A;  3V0E A;  2I42 A;  2GP0 A;  2E0T A;  2BIJ A;  1G1F A;  3F9A A;  1RPM A;  2HB1 A;  4R0S A;  2B49 A;  2B4S A;  2CM2 A;  2QDP A;  3BRH A;  1C88 A;  4GE2 A;  1G1G A;  2DXP A;  3QCM A;  4NYH A;  4RI4 A;  1G4U S;  2I6O A;  1JLN A;  3D9C A;  1G7F A;  1PTV A;  1LQF A;  3NME A;  3QKQ A;  3MMJ A;  1GWZ A;  4YAA A;  2PSZ A;  1EEN A;  2C46 A;  4BJO A;  2NT7 A;  1OHE A;  3H2X A;  2MBC A;  2YDU A;  3S3E A;  4D3Q A;  2R0B A;  4PVG A;  1YGU A;  5K9W A;  3BLT A;  1ZC0 A;  2I6M A;  4GS0 A;  2VEW A;  1NO6 A;  4JBC A;  2BV5 A;  4D3P A;  1NWL A;  1I57 A;  1ZCL A;  2H04 A;  1C83 A;  1PA9 A;  4JNB A;  2H02 A;  5KAD A;  1OES A;  2B3O A;  1PYN A;  3QCN A;  5KA0 A;  5K9V A;  3GXH A;  2Y96 A;  4ZI4 A;  3EB1 A;  2QEP A;  4ICZ A;  1A5Y A;  2CNF A;  1SUG A;  1YGR A;  4ZRT A;  5HDE A;  1KAV A;  2PA5 A;  4HJP A;  2CNG A;  3B7O A;  2VEU A;  2RF6 A;  1BZJ A;  2CNH A;  2PQ5 A;  3EMU A;  3ZMP A;  3S3F A;  1G7G A;  3RGQ A;  4OHH A;  3S3K A;  2HC1 A;  1Q1M A;  4S0G A;  3QKP A;  1EEO A;  1OEO X;  2HC2 A;  2QBR A;  4QUM A;  1YTN A;  4Y14 A;  1NNY A;  4B04 A;  2VEX A;  5KAC A;  2ESB A;  4NND A;  2SHP A;  2G6Z A;  1NL9 A;  2Y2F A;  5K24 A;  1RXD A;  1XM2 A;  3O4S A;  2I4G A;  3BLU A;  1WAX A;  2M3V A;  1YZ4 A;  1U26 A;  1M3G A;  3LJ8 A;  2I6P A;  2J16 A;  1FPR A;  2F70 A;  3D44 A;  2FH7 A;  1BZH A;  2ZN7 A;  2F6Y A;  3MOZ A;  2CNE A;  1I9S A;  3V0D A;  1VHR A;  1YN9 A;  3O5X A;  2BZL A;  5M43 A;  3F41 A;  3ZV2 A;  5KA3 A;  2HCM A;  3F99 A;  4RI5 A;  2QBP A;  2I4E A;  5IBS A;  2F71 A;  4Y2E A;  3AWF A;  3QCJ A;  1MKP A;  1T48 A;  2AZR A;  2NLK A;  2A8B A;  3U96 A;  2QBS A;  3I80 A;  3QCB A;  3RGO A;  1OHC A;  1Q6S A;  3A5J A;  1P15 A;  4YR8 B;  5K25 A;  2F6V A;  1L8K A;  1X24 A;  5EHR A;  2QDC A;  3AWG A;  5KA1 A;  1Q6J A;  1XBO A;  2B4P A;  1I9T A;  5KA2 A;  2I6J A;  4OHI A;  2OC3 A;  3ZM3 A;  2VEY A;  1C84 A;  4GFU A;  2CMA A;  1JF7 A;  3N0A A;  3D42 A;  3F9B A;  1OEM X;  3QCK A;  2B4O A;  4WOH A;  2OZ5 A;  1AAX A;  4I8N A;  4IKC A;  2AHS A;  4BPC A;  1PXH A;  4OHD A;  2NTA A;  4QBE A;  2JJD A;  1XRI A;  2Q05 A;  3QCC A;  2F46 A;  2VEV A;  4NWF A;  2OOQ A;  4MBB A;  2FJN A;  4RH9 A;  2HY3 A;  5K22 A;  4OHE A;  3S4E A;  4ZN5 A;  1BZC A;  2F6T A;  2F6Z A;  1ZZW A;  2PI7 A;  4R0T A;  4RKK A;  2I5X A;  1FPZ A;  3SME A;  3O4U A;  2HNQ A;  3S4O A;  3QCI A;  2CNI A;  3A5K A;  1Q6T A;  2CJZ A;  4DGP A;  2WGP A;  1YTS A;  2J17 A;  1R6H A;  2QDM A;  1GFY A;  4NWG A;  1FQ1 A;  4TVV A;  3EAX A;  5BZZ A;  4R30 A;  5BUG A;  3CWE A;  2CFV A;  3D1O A;  4H1O A;  1YTW A;  5I6V A;  3D1Q A;  4GWF A;  2F6W A;  4JMK A;  1YPT A;  4KYQ A;  1QXK A;  1ECV A;  3AWE A;  3QCH A;  2BGD A;  1ZCK A;  3QCE A;  4OHL A;  2I75 A;  3ZMQ A;  2A3K A;  3O3L A;  4KI9 A;  4QUN A;  2CM7 A;  1PH0 A;  3V0H A;  2B4U A;  5KA8 A;  4GE5 A;  1J4X A;  1OET A;  2QBQ A;  4RH5 A;  2PBN A;  2I3U A;  3QCF A;  2HVL A;  3ZM0 A;  3F81 A;  1LAR A;  2FJM A;  1WCH A;  2QCT A;  2GWO A;  2Q47 A;  5BZX A;  5KA9 A;  3OLR A;  2PT0 A;  5KAA A;  4PYH A;  2F6F A;  2OUD A;  1Q6P A;  1KAK A;  1C87 A;  3SR9 A;  4GE6 A;  3RZ2 A;  5K23 A;  3M4U A;  1PA1 A;  3CM3 A;  4AZ1 A;  1T4J A;  2CMC A;  4WU3 A;  1V3A A;  2HNP A;  4QAP A;  1Q6N A;  1U25 A;  4Z6B A;  2HXP A; 
#chains in the Genus database with same CATH topology
 2XPC A;  3I36 A;  2IMG A;  2H4K A;  1GG4 A;  3D1H A;  1PTU A;  2Y67 A;  3V0I A;  4GRZ A;  2AM2 A;  3UAG A;  4RHG A;  1ONY A;  3ZM2 A;  1G4W R;  4QAH A;  4GFV A;  4UAG A;  5EHP A;  5KA4 A;  3ZM1 A;  1U24 A;  1YWF A;  1OEU A;  4HRF A;  2C7S A;  2CM3 A;  4ERC A;  1OHD A;  2CM8 A;  2BGE A;  4DGX A;  1C85 A;  5GTJ A;  1Q6M A;  2P6X A;  2Y66 A;  5J8R A;  2H4V A;  3RO1 A;  5LXQ B;  3BM8 A;  3GXG A;  2J16 B;  3QCL A;  3V0J A;  3EU0 A;  3PYZ A;  4J51 A;  4H34 A;  1T49 A;  3EZZ A;  3NRS A;  1W7K A;  2QCJ A;  4WTY A;  1ONZ A;  4KYR A;  3MOW A;  2NZ6 A;  1NZ7 A;  1YFO A;  2CMB A;  2NV5 A;  5A5F A;  3O4T A;  4GRY A;  1FGS A;  1UAG A;  1PTT A;  2ZMM A;  1QZ0 A;  1GQQ A;  1XXP A;  3V0G A;  1G1H A;  4WU2 A;  1WRM A;  2H4G A;  2NT2 A;  5KA7 A;  4HJQ A;  5KAB A;  2AM1 A;  3PS5 A;  5MMZ B;  2WJP A;  3QCG A;  4RDD A;  3ZL8 A;  4D3R A;  1D5R A;  1NWE A;  1PTY A;  4JMJ A;  5IBM A;  2B07 A;  1C86 A;  2H03 A;  3S3H A;  1XXV A;  1L8G A;  2G59 A;  2I6I A;  5BX1 A;  1LYV A;  2P4D A;  4BUC A;  4NX8 A;  3V0F A;  3QCD A;  5AWX A;  2GJT A;  3I7Z A;  2I1Y A;  1OEV A;  2I4H A;  4QBW A;  3OMH A;  2I3R A;  3V0E A;  2I42 A;  2GP0 A;  2E0T A;  2BIJ A;  1G1F A;  1RPM A;  2HB1 A;  3F9A A;  4R0S A;  2B49 A;  2B4S A;  2CM2 A;  2QDP A;  3BRH A;  1C88 A;  4GE2 A;  1G1G A;  2DXP A;  3QCM A;  4NYH A;  2VTD A;  4RI4 A;  1G4U S;  2UUO A;  2I6O A;  1JLN A;  3D9C A;  1G7F A;  1PTV A;  1LQF A;  4CVM A;  3NME A;  2JFF A;  3QKQ A;  3MMJ A;  1GWZ A;  4YAA A;  2PSZ A;  1EEN A;  2C46 A;  4BJO A;  2NT7 A;  4BUB A;  1OHE A;  3H2X A;  2MBC A;  2YDU A;  3S3E A;  4D3Q A;  2R0B A;  4PVG A;  1YGU A;  5K9W A;  3BLT A;  1ZC0 A;  2I6M A;  2GCB A;  4GS0 A;  2VEW A;  1NO6 A;  4JBC A;  2BV5 A;  4D3P A;  1E0D A;  1NWL A;  1I57 A;  1ZCL A;  2GCA A;  2H04 A;  1C83 A;  1PA9 A;  4JNB A;  2H02 A;  5KAD A;  1OES A;  2B3O A;  1PYN A;  3QCN A;  5KA0 A;  5K9V A;  3GXH A;  2Y96 A;  4ZI4 A;  3EB1 A;  2QEP A;  4ICZ A;  1A5Y A;  2CNF A;  1SUG A;  1YGR A;  4ZRT A;  5HDE A;  1KAV A;  2PA5 A;  4HJP A;  2CNG A;  3B7O A;  2VEU A;  2RF6 A;  1BZJ A;  2CNH A;  2PQ5 A;  3EMU A;  3HN7 A;  5A5E A;  1P3D A;  3ZMP A;  3S3F A;  1G7G A;  3RGQ A;  2GC6 A;  1EEH A;  4OHH A;  3S3K A;  2HC1 A;  1Q1M A;  4S0G A;  3QKP A;  1EEO A;  1OEO X;  2HC2 A;  2QBR A;  4QUM A;  1YTN A;  4Y14 A;  1NNY A;  4B04 A;  1JBW A;  2VEX A;  5KAC A;  2ESB A;  4NND A;  2SHP A;  2G6Z A;  1NL9 A;  2Y2F A;  5K24 A;  1RXD A;  1XM2 A;  3O4S A;  2I4G A;  2JFH A;  3BLU A;  1WAX A;  2M3V A;  1YZ4 A;  4HV4 A;  1U26 A;  1M3G A;  3LJ8 A;  3LK7 A;  2I6P A;  2UUP A;  2J16 A;  1FPR A;  2F70 A;  3D44 A;  2FH7 A;  1BZH A;  2ZN7 A;  2F6Y A;  2UAG A;  3MOZ A;  2XJA A;  4CVL A;  2CNE A;  1P31 A;  1I9S A;  3V0D A;  1VHR A;  1YN9 A;  3O5X A;  2BZL A;  5M43 A;  3F41 A;  2Y1O A;  3ZV2 A;  5KA3 A;  2HCM A;  3F99 A;  4RI5 A;  2QBP A;  2I4E A;  5IBS A;  2F71 A;  4Y2E A;  3AWF A;  3QCJ A;  1MKP A;  1T48 A;  2AZR A;  2NLK A;  2A8B A;  3U96 A;  2QBS A;  3I80 A;  3QCB A;  3RGO A;  1OHC A;  1Q6S A;  3A5J A;  1P15 A;  4YR8 B;  5K25 A;  2F6V A;  1L8K A;  1X24 A;  5EHR A;  2QDC A;  3AWG A;  5KA1 A;  1Q6J A;  2VOS A;  1XBO A;  2B4P A;  1I9T A;  5KA2 A;  2I6J A;  4OHI A;  2OC3 A;  3ZM3 A;  2VEY A;  1C84 A;  4GFU A;  2CMA A;  1JF7 A;  3N0A A;  3D42 A;  3F9B A;  1OEM X;  3QCK A;  2B4O A;  4WOH A;  2OZ5 A;  1AAX A;  2X5O A;  4I8N A;  4IKC A;  2AHS A;  4BPC A;  2Y68 A;  1PXH A;  4OHD A;  2NTA A;  4QBE A;  2JJD A;  1XRI A;  2VOR A;  2Q05 A;  3QCC A;  1E8C A;  2F46 A;  2VEV A;  4NWF A;  2OOQ A;  4MBB A;  2FJN A;  4RH9 A;  2HY3 A;  5K22 A;  4OHE A;  3S4E A;  4ZN5 A;  1BZC A;  2F6T A;  2F6Z A;  1ZZW A;  2PI7 A;  4R0T A;  4RKK A;  1W78 A;  2I5X A;  1FPZ A;  3SME A;  3O4U A;  2HNQ A;  3S4O A;  3QCI A;  2CNI A;  3A5K A;  1Q6T A;  3ZM5 A;  2CJZ A;  4DGP A;  2WGP A;  1YTS A;  2J17 A;  1R6H A;  2QDM A;  1GFY A;  4NWG A;  1FQ1 A;  4TVV A;  3EAX A;  5BZZ A;  4R30 A;  5BUG A;  3CWE A;  2CFV A;  3D1O A;  4H1O A;  1YTW A;  4C13 A;  5I6V A;  1JBV A;  3ZM6 A;  3D1Q A;  4GWF A;  2F6W A;  4JMK A;  1YPT A;  4KYQ A;  1QXK A;  1ECV A;  3AWE A;  3QCH A;  3QCZ A;  2BGD A;  1ZCK A;  3QCE A;  4OHL A;  2I75 A;  3ZMQ A;  2A3K A;  3O3L A;  4QDI A;  4KI9 A;  4QUN A;  2CM7 A;  1PH0 A;  3V0H A;  2B4U A;  5KA8 A;  3N2A A;  4GE5 A;  2F00 A;  1O5Z A;  1J4X A;  1OET A;  2QBQ A;  4RH5 A;  2PBN A;  3MVN A;  2I3U A;  3QCF A;  2HVL A;  3ZM0 A;  3F81 A;  1LAR A;  2VTE A;  2FJM A;  1WCH A;  2GC5 A;  2QCT A;  2GWO A;  2Q47 A;  5BZX A;  5KA9 A;  1GQY A;  3OLR A;  4CVK A;  4C12 A;  2PT0 A;  5KAA A;  4PYH A;  2F6F A;  2OUD A;  1Q6P A;  4ZIY A;  4QF5 A;  1KAK A;  1C87 A;  2WTZ A;  3SR9 A;  4GE6 A;  3RZ2 A;  5K23 A;  3M4U A;  1PA1 A;  3CM3 A;  4AZ1 A;  1T4J A;  2CMC A;  1J6U A;  4WU3 A;  2JFG A;  1V3A A;  2HNP A;  4QAP A;  1Q6N A;  1U25 A;  4Z6B A;  2HXP A; 
#chains in the Genus database with same CATH homology
 3I36 A;  2IMG A;  2H4K A;  3D1H A;  1PTU A;  3V0I A;  4GRZ A;  4RHG A;  1ONY A;  3ZM2 A;  1G4W R;  4QAH A;  4GFV A;  5EHP A;  5KA4 A;  3ZM1 A;  1U24 A;  1YWF A;  1OEU A;  4HRF A;  2C7S A;  2CM3 A;  4ERC A;  1OHD A;  2CM8 A;  2BGE A;  4DGX A;  1C85 A;  5GTJ A;  1Q6M A;  2P6X A;  5J8R A;  2H4V A;  3RO1 A;  5LXQ B;  3BM8 A;  3GXG A;  2J16 B;  3QCL A;  3V0J A;  3EU0 A;  4J51 A;  4H34 A;  1T49 A;  3EZZ A;  2QCJ A;  4WTY A;  1ONZ A;  4KYR A;  3MOW A;  2NZ6 A;  1NZ7 A;  1YFO A;  2CMB A;  2NV5 A;  3O4T A;  4GRY A;  1PTT A;  2ZMM A;  1QZ0 A;  1XXP A;  3V0G A;  1G1H A;  4WU2 A;  1WRM A;  2H4G A;  2NT2 A;  5KA7 A;  4HJQ A;  5KAB A;  3PS5 A;  5MMZ B;  3QCG A;  4RDD A;  4D3R A;  1D5R A;  1NWE A;  1PTY A;  4JMJ A;  5IBM A;  2B07 A;  1C86 A;  2H03 A;  3S3H A;  1XXV A;  1L8G A;  2G59 A;  2I6I A;  5BX1 A;  1LYV A;  2P4D A;  4NX8 A;  3V0F A;  3QCD A;  5AWX A;  2GJT A;  3I7Z A;  2I1Y A;  1OEV A;  2I4H A;  4QBW A;  3OMH A;  2I3R A;  3V0E A;  2I42 A;  2GP0 A;  2E0T A;  2BIJ A;  1G1F A;  3F9A A;  1RPM A;  2HB1 A;  4R0S A;  2B49 A;  2B4S A;  2CM2 A;  2QDP A;  3BRH A;  1C88 A;  4GE2 A;  1G1G A;  2DXP A;  3QCM A;  4NYH A;  4RI4 A;  1G4U S;  2I6O A;  1JLN A;  3D9C A;  1G7F A;  1PTV A;  1LQF A;  3NME A;  3QKQ A;  3MMJ A;  1GWZ A;  4YAA A;  2PSZ A;  1EEN A;  2C46 A;  4BJO A;  2NT7 A;  1OHE A;  3H2X A;  2MBC A;  2YDU A;  3S3E A;  4D3Q A;  2R0B A;  4PVG A;  1YGU A;  5K9W A;  3BLT A;  1ZC0 A;  2I6M A;  4GS0 A;  2VEW A;  1NO6 A;  4JBC A;  2BV5 A;  4D3P A;  1NWL A;  1I57 A;  1ZCL A;  2H04 A;  1C83 A;  1PA9 A;  4JNB A;  2H02 A;  5KAD A;  1OES A;  2B3O A;  1PYN A;  3QCN A;  5KA0 A;  5K9V A;  3GXH A;  2Y96 A;  4ZI4 A;  3EB1 A;  2QEP A;  4ICZ A;  1A5Y A;  2CNF A;  1SUG A;  1YGR A;  4ZRT A;  5HDE A;  1KAV A;  2PA5 A;  4HJP A;  2CNG A;  3B7O A;  2VEU A;  2RF6 A;  1BZJ A;  2CNH A;  2PQ5 A;  3EMU A;  3ZMP A;  3S3F A;  1G7G A;  3RGQ A;  4OHH A;  3S3K A;  2HC1 A;  1Q1M A;  4S0G A;  3QKP A;  1EEO A;  1OEO X;  2HC2 A;  2QBR A;  4QUM A;  1YTN A;  4Y14 A;  1NNY A;  4B04 A;  2VEX A;  5KAC A;  2ESB A;  4NND A;  2SHP A;  2G6Z A;  1NL9 A;  2Y2F A;  5K24 A;  1RXD A;  1XM2 A;  3O4S A;  2I4G A;  3BLU A;  1WAX A;  2M3V A;  1YZ4 A;  1U26 A;  1M3G A;  3LJ8 A;  2I6P A;  2J16 A;  1FPR A;  2F70 A;  3D44 A;  2FH7 A;  1BZH A;  2ZN7 A;  2F6Y A;  3MOZ A;  2CNE A;  1I9S A;  3V0D A;  1VHR A;  1YN9 A;  3O5X A;  2BZL A;  5M43 A;  3F41 A;  3ZV2 A;  5KA3 A;  2HCM A;  3F99 A;  4RI5 A;  2QBP A;  2I4E A;  5IBS A;  2F71 A;  4Y2E A;  3AWF A;  3QCJ A;  1MKP A;  1T48 A;  2AZR A;  2NLK A;  2A8B A;  3U96 A;  2QBS A;  3I80 A;  3QCB A;  3RGO A;  1OHC A;  1Q6S A;  3A5J A;  1P15 A;  4YR8 B;  5K25 A;  2F6V A;  1L8K A;  1X24 A;  5EHR A;  2QDC A;  3AWG A;  5KA1 A;  1Q6J A;  1XBO A;  2B4P A;  1I9T A;  5KA2 A;  2I6J A;  4OHI A;  2OC3 A;  3ZM3 A;  2VEY A;  1C84 A;  4GFU A;  2CMA A;  1JF7 A;  3N0A A;  3D42 A;  3F9B A;  1OEM X;  3QCK A;  2B4O A;  4WOH A;  2OZ5 A;  1AAX A;  4I8N A;  4IKC A;  2AHS A;  4BPC A;  1PXH A;  4OHD A;  2NTA A;  4QBE A;  2JJD A;  1XRI A;  2Q05 A;  3QCC A;  2F46 A;  2VEV A;  4NWF A;  2OOQ A;  4MBB A;  2FJN A;  4RH9 A;  2HY3 A;  5K22 A;  4OHE A;  3S4E A;  4ZN5 A;  1BZC A;  2F6T A;  2F6Z A;  1ZZW A;  2PI7 A;  4R0T A;  4RKK A;  2I5X A;  1FPZ A;  3SME A;  3O4U A;  2HNQ A;  3S4O A;  3QCI A;  2CNI A;  3A5K A;  1Q6T A;  2CJZ A;  4DGP A;  2WGP A;  1YTS A;  2J17 A;  1R6H A;  2QDM A;  1GFY A;  4NWG A;  1FQ1 A;  4TVV A;  3EAX A;  5BZZ A;  4R30 A;  5BUG A;  3CWE A;  2CFV A;  3D1O A;  4H1O A;  1YTW A;  5I6V A;  3D1Q A;  4GWF A;  2F6W A;  4JMK A;  1YPT A;  4KYQ A;  1QXK A;  1ECV A;  3AWE A;  3QCH A;  2BGD A;  1ZCK A;  3QCE A;  4OHL A;  2I75 A;  3ZMQ A;  2A3K A;  3O3L A;  4KI9 A;  4QUN A;  2CM7 A;  1PH0 A;  3V0H A;  2B4U A;  5KA8 A;  4GE5 A;  1J4X A;  1OET A;  2QBQ A;  4RH5 A;  2PBN A;  2I3U A;  3QCF A;  2HVL A;  3ZM0 A;  3F81 A;  1LAR A;  2FJM A;  1WCH A;  2QCT A;  2GWO A;  2Q47 A;  5BZX A;  5KA9 A;  3OLR A;  2PT0 A;  5KAA A;  4PYH A;  2F6F A;  2OUD A;  1Q6P A;  1KAK A;  1C87 A;  3SR9 A;  4GE6 A;  3RZ2 A;  5K23 A;  3M4U A;  1PA1 A;  3CM3 A;  4AZ1 A;  1T4J A;  2CMC A;  4WU3 A;  1V3A A;  2HNP A;  4QAP A;  1Q6N A;  1U25 A;  4Z6B A;  2HXP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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