1G1GA

Crystal structure of protein tyrosine phosphatase 1b complexed with a mono-phosphorylated peptide (etdy(ptr)rkggkgll) from the insulin receptor kinase
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
298
structure length
298
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHASAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
pubmed doi rcsb
molecule tags Hydrolase, signaling protein
source organism Homo sapiens
molecule keywords PROTEIN TYROSINE PHOSPHATASE 1B
total genus 97
structure length 298
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1g1gA00
2I4EA 1JLNA 2HC1A 1VHRA 1YTSA 2E0TA 4JNBA 2I6JA 4GFVA 4RHGA 1NO6A 3EB1A 2QDCA 2QBRA 3QCGA 1RXDA 2HB1A 1ZZWA 2I6OA 1G1HA 2J17A 2YDUA 1PTYA 1YZ4A 2QBQA 1I9SA 3D44A 3F9BA 1ZCLA 3BRHA 4YAAA 3QCIA 3ZM0A 2CM8A 4NYHA 1BZJA 3S3HA 3BLTA 1ECVA 1G7GA 1X24A 4WTYA 2HNQA 4HJQA 1A5YA 3I80A 5KA2A 3V0DA 3I7ZA 2CJZA 1FQ1A 2B4SA 3O5XA 1XBOA 3H2XA 1ZC0A 3QCJA 4GRZA 3QCNA 4BPCA 1Q1MA 5KABA 5K9VA 4I8NA 1OEVA 3ZM1A 2F70A 3EAXA 3V0JA 2PI7A 3ZV2A 5K25A 3V0GA 3RGQA 2P4DA 2RF6A 5K9WA 5LXQB 1C88A 4ZI4A 2FH7A 4PVGA 2I3RA 2ESBA 3QCLA 5EHRA 5HDEA 1OHEA 3EZZA 4JMKA 3RO1A 2NV5A 2BGEA 5KA3A 2PBNA 4GWFA 2AZRA 3ZMPA 2I3UA 1WCHA 4QAPA 2CMCA 1ONYA 4OHIA 2PT0A 2BZLA 3S4EA 3RGOA 5GTJA 3D1HA 1YWFA 2C7SA 3A5JA 2VEUA 2BV5A 1U26A 2P6XA 4OHDA 1ZCKA 1U24A 2I1YA 2H04A 2HNPA 2PSZA 1Q6JA 1XRIA 2Y2FA 3F81A 4QUMA 4RI4A 1C86A 1MKPA 3D1QA 5K24A 5BZXA 4RH5A 2F71A 4GE5A 1FPRA 1JF7A 4NX8A 1PA1A 2BGDA 2HVLA 1LQFA 2F6ZA 4ERCA 1YGRA 4RKKA 1NWEA 4RDDA 1I9TA 2QDPA 2A8BA 3F99A 3ZM2A 3D42A 4DGPA 4H1OA 1NL9A 2QCTA 2I6IA 2H4KA 1T4JA 5KA1A 4QUNA 2CMAA 3BM8A 4OHLA 4HRFA 2J16B 1QZ0A 1G1FA 2WGPA 4GE2A 1KAVA 3QCFA 4AZ1A 2H4GA 2VEVA 3V0FA 3RZ2A 4R30A 3BLUA 3AWFA 2VEYA 1YTWA 5IBSA 3CWEA 3N0AA 5I6VA 3OLRA 2B4UA 1GFYA 1Q6NA 2CNHA 2IMGA 4D3QA 5KA0A 4NWGA 1EEOA 1Q6SA 4NNDA 4WOHA 4D3PA 1QXKA 5BX1A 1J4XA 1Q6PA 2B07A 2BIJA 5J8RA 3SR9A 1R6HA 3O4UA 1PYNA 1PTVA 2H03A 2NT7A 2CM7A 5AWXA 3LJ8A 1BZHA 2A3KA 2I42A 1G7FA 3ZMQA 1OETA 1XM2A 2OOQA 4OHEA 3MOZA 1OEMX 2I4GA 2HCMA 4J51A 4TVVA 3NMEA 4BJOA 2B3OA 2I75A 1PH0A 5KA7A 1C87A 1I57A 1OHDA 5KA4A 1PA9A 4Z6BA 1Q6TA 1T49A 4IKCA 2HY3A 4Y14A 2FJMA 3S3FA 4WU2A 3U96A 2F46A 5KA8A 4ICZA 4PYHA 1FPZA 2GWOA 2CNGA 3OMHA 3V0IA 2CNIA 1V3AA 3D9CA 2ZMMA 2H02A 1G1GA 1PTTA 1SUGA 2Y96A 1G4US 1YFOA 2CNFA 3QCKA 2OC3A 5M43A 2QBSA 4WU3A 4B04A 5EHPA 3V0EA 4ZRTA 3ZM3A 2QBPA 3S3EA 2DXPA 4RI5A 2F6TA 2Q47A 5K22A 2C46A 3D1OA 1LYVA 2I6MA 1XXPA 1L8GA 2FJNA 5KACA 3B7OA 1NNYA 1M3GA 3QCMA 2VEWA 2B4PA 4HJPA 3EMUA 4NWFA 1G4WR 4RH9A 3QCDA 3QCEA 3O4TA 3GXHA 2B49A 3M4UA 1C83A 1OESA 3AWGA 3F9AA 2F6WA 4KYQA 4S0GA 2ZN7A 1NZ7A 4QAHA 4QBWA 1GWZA 2J16A 2GJTA 5BUGA 1EENA 5BZZA 1OHCA 2OUDA 2CMBA 1KAKA 4H34A 1YGUA 2NTAA 5KADA 3QKQA 2OZ5A 3QCCA 2CFVA 3MMJA 3V0HA 2VEXA 2F6FA 4QBEA 3AWEA 1P15A 1WRMA 1D5RA 2QDMA 4KI9A 2F6YA 4OHHA 2QCJA 3EU0A 4R0SA 5IBMA 2HXPA 1NWLA 2MBCA 3GXGA 2G6ZA 3A5KA 2AHSA 4GRYA 2I5XA 4YR8B 2F6VA 1C85A 1L8KA 2R0BA 1PTUA 2CM2A 5K23A 2CNEA 4KYRA 3QCHA 1XXVA 5KAAA 4R0TA 3CM3A 1T48A 4MBBA 2NLKA 2JJDA 3O4SA 1PXHA 2I6PA 2B4OA 2NZ6A 2SHPA 2NT2A 4Y2EA 1YPTA 3S3KA 1Q6MA 3QCBA 2I4HA 5MMZB 1YN9A 4JBCA 2PQ5A 3QKPA 4GE6A 1AAXA 3I36A 4GS0A 3F41A 2PA5A 3PS5A 1WAXA 4JMJA 1RPMA 2CM3A 4ZN5A 2G59A 2M3VA 1U25A 3MOWA 1BZCA 2H4VA 3O3LA 2HC2A 1LARA 2QEPA 1C84A 3SMEA 5KA9A 1YTNA 2Q05A 2GP0A 4DGXA 4D3RA 3S4OA 1OEOX 1ONZA 1OEUA 4GFUA
chains in the Genus database with same CATH superfamily
2I4EA 1JLNA 2HC1A 1VHRA 1YTSA 2E0TA 4JNBA 2I6JA 4GFVA 4RHGA 1NO6A 5A5FA 3EB1A 2QDCA 2GCBA 2QBRA 3QCGA 1RXDA 2HB1A 1ZZWA 2I6OA 4ZIYA 5A5EA 1G1HA 2VTDA 2J17A 4BUCA 2YDUA 1FGSA 1PTYA 1YZ4A 2QBQA 4CVKA 1I9SA 2GC5A 3D44A 3F9BA 1ZCLA 2GCAA 3BRHA 4YAAA 4C12A 3QCIA 3PYZA 3ZM0A 2CM8A 4NYHA 4BUBA 3ZM6A 1BZJA 3S3HA 3BLTA 1ECVA 1G7GA 1X24A 4WTYA 2HNQA 4HJQA 1A5YA 1JBVA 3I80A 2AM1A 5KA2A 3V0DA 3I7ZA 2CJZA 1FQ1A 2B4SA 3O5XA 1XBOA 3H2XA 1ZC0A 3QCJA 4GRZA 3QCNA 4BPCA 1Q1MA 5KABA 5K9VA 4I8NA 1OEVA 3ZM1A 2F70A 3EAXA 3V0JA 2PI7A 3ZV2A 5K25A 3V0GA 3RGQA 2P4DA 1GG4A 2RF6A 5K9WA 2GC6A 5LXQB 1C88A 4ZI4A 2FH7A 4PVGA 2I3RA 2ESBA 3QCLA 5EHRA 5HDEA 1P31A 1OHEA 3EZZA 4JMKA 3RO1A 2NV5A 2BGEA 5KA3A 2PBNA 4GWFA 2AZRA 3ZMPA 2Y1OA 2I3UA 1WCHA 4QAPA 4QF5A 2CMCA 2VOSA 1ONYA 2UUPA 4OHIA 2PT0A 2BZLA 3S4EA 3RGOA 5GTJA 3D1HA 1YWFA 2AM2A 2C7SA 3A5JA 2VEUA 2BV5A 1U26A 2P6XA 4OHDA 1ZCKA 1U24A 2I1YA 2H04A 2HNPA 2PSZA 1Q6JA 1XRIA 2Y2FA 3F81A 4QUMA 4RI4A 1C86A 1MKPA 3D1QA 5K24A 1O5ZA 5BZXA 4RH5A 2F71A 4GE5A 1FPRA 1JF7A 4NX8A 1PA1A 2BGDA 4QDIA 1W7KA 2HVLA 1LQFA 2F6ZA 4HV4A 4ERCA 1YGRA 4RKKA 1NWEA 4RDDA 1UAGA 1I9TA 2QDPA 2A8BA 3F99A 3ZM2A 3D42A 4DGPA 4H1OA 1NL9A 2QCTA 2I6IA 2H4KA 3UAGA 1T4JA 5KA1A 4QUNA 2CMAA 3BM8A 4OHLA 4HRFA 2J16B 1QZ0A 1G1FA 2WGPA 4GE2A 1KAVA 3QCFA 4AZ1A 2H4GA 2VEVA 3V0FA 3RZ2A 4R30A 3BLUA 3AWFA 2VEYA 1YTWA 5IBSA 3CWEA 4UAGA 4C13A 3N0AA 2Y66A 5I6VA 3OLRA 2B4UA 1GFYA 1E0DA 1Q6NA 2CNHA 2UAGA 2IMGA 4D3QA 5KA0A 4NWGA 1EEOA 1Q6SA 4NNDA 4WOHA 4D3PA 1QXKA 5BX1A 1J4XA 1Q6PA 2B07A 2BIJA 2XPCA 5J8RA 3SR9A 1R6HA 2Y67A 1PYNA 3O4UA 1PTVA 2H03A 2NT7A 2CM7A 2Y68A 5AWXA 1BZHA 2A3KA 2I42A 3LJ8A 1G7FA 3ZMQA 1OETA 1XM2A 2OOQA 4OHEA 3MOZA 1OEMX 2I4GA 2HCMA 4J51A 4TVVA 3NMEA 4BJOA 2VORA 2B3OA 2I75A 1PH0A 5KA7A 1C87A 1I57A 1OHDA 5KA4A 1PA9A 4Z6BA 1Q6TA 1T49A 4IKCA 2HY3A 4Y14A 2FJMA 3S3FA 3LK7A 4WU2A 2F00A 3U96A 2F46A 5KA8A 4ICZA 4PYHA 1FPZA 2GWOA 2CNGA 3OMHA 3V0IA 2CNIA 1V3AA 3D9CA 2ZMMA 2H02A 1G1GA 1PTTA 1SUGA 2Y96A 1G4US 2JFGA 2XJAA 1YFOA 2CNFA 3QCKA 2OC3A 5M43A 2QBSA 4WU3A 4B04A 2JFHA 5EHPA 3V0EA 1W78A 4ZRTA 3ZM3A 2QBPA 3S3EA 2DXPA 4RI5A 2F6TA 2Q47A 5K22A 2C46A 3D1OA 1LYVA 2I6MA 1XXPA 1L8GA 2FJNA 1GQQA 5KACA 3B7OA 1NNYA 1M3GA 3QCMA 2VEWA 2B4PA 4HJPA 3EMUA 4NWFA 1G4WR 1P3DA 4RH9A 3QCDA 3QCEA 3O4TA 3GXHA 2B49A 3M4UA 1C83A 1OESA 3AWGA 3F9AA 2F6WA 4KYQA 4S0GA 2ZN7A 1NZ7A 4QAHA 4QBWA 1GWZA 2X5OA 2J16A 2GJTA 5BUGA 1EENA 5BZZA 1OHCA 2WJPA 2OUDA 2CMBA 1KAKA 4H34A 2JFFA 1YGUA 2NTAA 5KADA 3QKQA 2OZ5A 3NRSA 3QCCA 2CFVA 3MMJA 3V0HA 2VEXA 2F6FA 4QBEA 3AWEA 1P15A 1WRMA 1D5RA 2QDMA 4KI9A 2F6YA 4OHHA 2QCJA 3EU0A 4R0SA 5IBMA 4CVLA 2HXPA 1NWLA 2WTZA 2MBCA 3GXGA 2G6ZA 3A5KA 2AHSA 4GRYA 2I5XA 4YR8B 2F6VA 1C85A 1L8KA 2R0BA 1PTUA 2CM2A 3HN7A 5K23A 2CNEA 4KYRA 3QCHA 1XXVA 5KAAA 4R0TA 3CM3A 1T48A 3MVNA 4MBBA 2NLKA 2JJDA 1GQYA 3O4SA 1PXHA 2I6PA 2B4OA 2NZ6A 2SHPA 2UUOA 2NT2A 4Y2EA 3QCZA 1EEHA 1YPTA 3S3KA 1Q6MA 3QCBA 2I4HA 4CVMA 5MMZB 1YN9A 1J6UA 4JBCA 2PQ5A 3QKPA 4GE6A 1JBWA 1AAXA 3I36A 4GS0A 3F41A 2PA5A 3PS5A 3N2AA 1WAXA 4JMJA 3ZM5A 1RPMA 2CM3A 4ZN5A 2G59A 2M3VA 1U25A 3MOWA 1BZCA 2H4VA 3ZL8A 3O3LA 2HC2A 1LARA 2QEPA 2VTEA 1C84A 3SMEA 5KA9A 1YTNA 2Q05A 2GP0A 4DGXA 1E8CA 4D3RA 3S4OA 1OEOX 1ONZA 1OEUA 4GFUA
chains in the Genus database with same CATH topology
2I4EA 1JLNA 2HC1A 1VHRA 1YTSA 2E0TA 4JNBA 2I6JA 4GFVA 4RHGA 1NO6A 3EB1A 2QDCA 2QBRA 3QCGA 1RXDA 2HB1A 1ZZWA 2I6OA 1G1HA 2J17A 2YDUA 1PTYA 1YZ4A 2QBQA 1I9SA 3D44A 3F9BA 1ZCLA 3BRHA 4YAAA 3QCIA 3ZM0A 2CM8A 4NYHA 1BZJA 3S3HA 3BLTA 1ECVA 1G7GA 1X24A 4WTYA 2HNQA 4HJQA 1A5YA 3I80A 5KA2A 3V0DA 3I7ZA 2CJZA 1FQ1A 2B4SA 3O5XA 1XBOA 3H2XA 1ZC0A 3QCJA 4GRZA 3QCNA 4BPCA 1Q1MA 5KABA 5K9VA 4I8NA 1OEVA 3ZM1A 2F70A 3EAXA 3V0JA 2PI7A 3ZV2A 5K25A 3V0GA 3RGQA 2P4DA 2RF6A 5K9WA 5LXQB 1C88A 4ZI4A 2FH7A 4PVGA 2I3RA 2ESBA 3QCLA 5EHRA 5HDEA 1OHEA 3EZZA 4JMKA 3RO1A 2NV5A 2BGEA 5KA3A 2PBNA 4GWFA 2AZRA 3ZMPA 2I3UA 1WCHA 4QAPA 2CMCA 1ONYA 4OHIA 2PT0A 2BZLA 3S4EA 3RGOA 5GTJA 3D1HA 1YWFA 2C7SA 3A5JA 2VEUA 2BV5A 1U26A 2P6XA 4OHDA 1ZCKA 1U24A 2I1YA 2H04A 2HNPA 2PSZA 1Q6JA 1XRIA 2Y2FA 3F81A 4QUMA 4RI4A 1C86A 1MKPA 3D1QA 5K24A 5BZXA 4RH5A 2F71A 4GE5A 1FPRA 1JF7A 4NX8A 1PA1A 2BGDA 2HVLA 1LQFA 2F6ZA 4ERCA 1YGRA 4RKKA 1NWEA 4RDDA 1I9TA 2QDPA 2A8BA 3F99A 3ZM2A 3D42A 4DGPA 4H1OA 1NL9A 2QCTA 2I6IA 2H4KA 1T4JA 5KA1A 4QUNA 2CMAA 3BM8A 4OHLA 4HRFA 2J16B 1QZ0A 1G1FA 2WGPA 4GE2A 1KAVA 3QCFA 4AZ1A 2H4GA 2VEVA 3V0FA 3RZ2A 4R30A 3BLUA 3AWFA 2VEYA 1YTWA 5IBSA 3CWEA 3N0AA 5I6VA 3OLRA 2B4UA 1GFYA 1Q6NA 2CNHA 2IMGA 4D3QA 5KA0A 4NWGA 1EEOA 1Q6SA 4NNDA 4WOHA 4D3PA 1QXKA 5BX1A 1J4XA 1Q6PA 2B07A 2BIJA 5J8RA 3SR9A 1R6HA 3O4UA 1PYNA 1PTVA 2H03A 2NT7A 2CM7A 5AWXA 3LJ8A 1BZHA 2A3KA 2I42A 1G7FA 3ZMQA 1OETA 1XM2A 2OOQA 4OHEA 3MOZA 1OEMX 2I4GA 2HCMA 4J51A 4TVVA 3NMEA 4BJOA 2B3OA 2I75A 1PH0A 5KA7A 1C87A 1I57A 1OHDA 5KA4A 1PA9A 4Z6BA 1Q6TA 1T49A 4IKCA 2HY3A 4Y14A 2FJMA 3S3FA 4WU2A 3U96A 2F46A 5KA8A 4ICZA 4PYHA 1FPZA 2GWOA 2CNGA 3OMHA 3V0IA 2CNIA 1V3AA 3D9CA 2ZMMA 2H02A 1G1GA 1PTTA 1SUGA 2Y96A 1G4US 1YFOA 2CNFA 3QCKA 2OC3A 5M43A 2QBSA 4WU3A 4B04A 5EHPA 3V0EA 4ZRTA 3ZM3A 2QBPA 3S3EA 2DXPA 4RI5A 2F6TA 2Q47A 5K22A 2C46A 3D1OA 1LYVA 2I6MA 1XXPA 1L8GA 2FJNA 5KACA 3B7OA 1NNYA 1M3GA 3QCMA 2VEWA 2B4PA 4HJPA 3EMUA 4NWFA 1G4WR 4RH9A 3QCDA 3QCEA 3O4TA 3GXHA 2B49A 3M4UA 1C83A 1OESA 3AWGA 3F9AA 2F6WA 4KYQA 4S0GA 2ZN7A 1NZ7A 4QAHA 4QBWA 1GWZA 2J16A 2GJTA 5BUGA 1EENA 5BZZA 1OHCA 2OUDA 2CMBA 1KAKA 4H34A 1YGUA 2NTAA 5KADA 3QKQA 2OZ5A 3QCCA 2CFVA 3MMJA 3V0HA 2VEXA 2F6FA 4QBEA 3AWEA 1P15A 1WRMA 1D5RA 2QDMA 4KI9A 2F6YA 4OHHA 2QCJA 3EU0A 4R0SA 5IBMA 2HXPA 1NWLA 2MBCA 3GXGA 2G6ZA 3A5KA 2AHSA 4GRYA 2I5XA 4YR8B 2F6VA 1C85A 1L8KA 2R0BA 1PTUA 2CM2A 5K23A 2CNEA 4KYRA 3QCHA 1XXVA 5KAAA 4R0TA 3CM3A 1T48A 4MBBA 2NLKA 2JJDA 3O4SA 1PXHA 2I6PA 2B4OA 2NZ6A 2SHPA 2NT2A 4Y2EA 1YPTA 3S3KA 1Q6MA 3QCBA 2I4HA 5MMZB 1YN9A 4JBCA 2PQ5A 3QKPA 4GE6A 1AAXA 3I36A 4GS0A 3F41A 2PA5A 3PS5A 1WAXA 4JMJA 1RPMA 2CM3A 4ZN5A 2G59A 2M3VA 1U25A 3MOWA 1BZCA 2H4VA 3O3LA 2HC2A 1LARA 2QEPA 1C84A 3SMEA 5KA9A 1YTNA 2Q05A 2GP0A 4DGXA 4D3RA 3S4OA 1OEOX 1ONZA 1OEUA 4GFUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I4E A;  1JLN A;  2HC1 A;  1VHR A;  1YTS A;  2E0T A;  4JNB A;  2I6J A;  4GFV A;  4RHG A;  1NO6 A;  3EB1 A;  2QDC A;  2QBR A;  3QCG A;  1RXD A;  2HB1 A;  1ZZW A;  2I6O A;  1G1H A;  2J17 A;  2YDU A;  1PTY A;  1YZ4 A;  2QBQ A;  1I9S A;  3D44 A;  3F9B A;  1ZCL A;  3BRH A;  4YAA A;  3QCI A;  3ZM0 A;  2CM8 A;  4NYH A;  1BZJ A;  3S3H A;  3BLT A;  1ECV A;  1G7G A;  1X24 A;  4WTY A;  2HNQ A;  4HJQ A;  1A5Y A;  3I80 A;  5KA2 A;  3V0D A;  3I7Z A;  2CJZ A;  1FQ1 A;  2B4S A;  3O5X A;  1XBO A;  3H2X A;  1ZC0 A;  3QCJ A;  4GRZ A;  3QCN A;  4BPC A;  1Q1M A;  5KAB A;  5K9V A;  4I8N A;  1OEV A;  3ZM1 A;  2F70 A;  3EAX A;  3V0J A;  2PI7 A;  3ZV2 A;  5K25 A;  3V0G A;  3RGQ A;  2P4D A;  2RF6 A;  5K9W A;  5LXQ B;  1C88 A;  4ZI4 A;  2FH7 A;  4PVG A;  2I3R A;  2ESB A;  3QCL A;  5EHR A;  5HDE A;  1OHE A;  3EZZ A;  4JMK A;  3RO1 A;  2NV5 A;  2BGE A;  5KA3 A;  2PBN A;  4GWF A;  2AZR A;  3ZMP A;  2I3U A;  1WCH A;  4QAP A;  2CMC A;  1ONY A;  4OHI A;  2PT0 A;  2BZL A;  3S4E A;  3RGO A;  5GTJ A;  3D1H A;  1YWF A;  2C7S A;  3A5J A;  2VEU A;  2BV5 A;  1U26 A;  2P6X A;  4OHD A;  1ZCK A;  1U24 A;  2I1Y A;  2H04 A;  2HNP A;  2PSZ A;  1Q6J A;  1XRI A;  2Y2F A;  3F81 A;  4QUM A;  4RI4 A;  1C86 A;  1MKP A;  3D1Q A;  5K24 A;  5BZX A;  4RH5 A;  2F71 A;  4GE5 A;  1FPR A;  1JF7 A;  4NX8 A;  1PA1 A;  2BGD A;  2HVL A;  1LQF A;  2F6Z A;  4ERC A;  1YGR A;  4RKK A;  1NWE A;  4RDD A;  1I9T A;  2QDP A;  2A8B A;  3F99 A;  3ZM2 A;  3D42 A;  4DGP A;  4H1O A;  1NL9 A;  2QCT A;  2I6I A;  2H4K A;  1T4J A;  5KA1 A;  4QUN A;  2CMA A;  3BM8 A;  4OHL A;  4HRF A;  2J16 B;  1QZ0 A;  1G1F A;  2WGP A;  4GE2 A;  1KAV A;  3QCF A;  4AZ1 A;  2H4G A;  2VEV A;  3V0F A;  3RZ2 A;  4R30 A;  3BLU A;  3AWF A;  2VEY A;  1YTW A;  5IBS A;  3CWE A;  3N0A A;  5I6V A;  3OLR A;  2B4U A;  1GFY A;  1Q6N A;  2CNH A;  2IMG A;  4D3Q A;  5KA0 A;  4NWG A;  1EEO A;  1Q6S A;  4NND A;  4WOH A;  4D3P A;  1QXK A;  5BX1 A;  1J4X A;  1Q6P A;  2B07 A;  2BIJ A;  5J8R A;  3SR9 A;  1R6H A;  3O4U A;  1PYN A;  1PTV A;  2H03 A;  2NT7 A;  2CM7 A;  5AWX A;  3LJ8 A;  1BZH A;  2A3K A;  2I42 A;  1G7F A;  3ZMQ A;  1OET A;  1XM2 A;  2OOQ A;  4OHE A;  3MOZ A;  1OEM X;  2I4G A;  2HCM A;  4J51 A;  4TVV A;  3NME A;  4BJO A;  2B3O A;  2I75 A;  1PH0 A;  5KA7 A;  1C87 A;  1I57 A;  1OHD A;  5KA4 A;  1PA9 A;  4Z6B A;  1Q6T A;  1T49 A;  4IKC A;  2HY3 A;  4Y14 A;  2FJM A;  3S3F A;  4WU2 A;  3U96 A;  2F46 A;  5KA8 A;  4ICZ A;  4PYH A;  1FPZ A;  2GWO A;  2CNG A;  3OMH A;  3V0I A;  2CNI A;  1V3A A;  3D9C A;  2ZMM A;  2H02 A;  1G1G A;  1PTT A;  1SUG A;  2Y96 A;  1G4U S;  1YFO A;  2CNF A;  3QCK A;  2OC3 A;  5M43 A;  2QBS A;  4WU3 A;  4B04 A;  5EHP A;  3V0E A;  4ZRT A;  3ZM3 A;  2QBP A;  3S3E A;  2DXP A;  4RI5 A;  2F6T A;  2Q47 A;  5K22 A;  2C46 A;  3D1O A;  1LYV A;  2I6M A;  1XXP A;  1L8G A;  2FJN A;  5KAC A;  3B7O A;  1NNY A;  1M3G A;  3QCM A;  2VEW A;  2B4P A;  4HJP A;  3EMU A;  4NWF A;  1G4W R;  4RH9 A;  3QCD A;  3QCE A;  3O4T A;  3GXH A;  2B49 A;  3M4U A;  1C83 A;  1OES A;  3AWG A;  3F9A A;  2F6W A;  4KYQ A;  4S0G A;  2ZN7 A;  1NZ7 A;  4QAH A;  4QBW A;  1GWZ A;  2J16 A;  2GJT A;  5BUG A;  1EEN A;  5BZZ A;  1OHC A;  2OUD A;  2CMB A;  1KAK A;  4H34 A;  1YGU A;  2NTA A;  5KAD A;  3QKQ A;  2OZ5 A;  3QCC A;  2CFV A;  3MMJ A;  3V0H A;  2VEX A;  2F6F A;  4QBE A;  3AWE A;  1P15 A;  1WRM A;  1D5R A;  2QDM A;  4KI9 A;  2F6Y A;  4OHH A;  2QCJ A;  3EU0 A;  4R0S A;  5IBM A;  2HXP A;  1NWL A;  2MBC A;  3GXG A;  2G6Z A;  3A5K A;  2AHS A;  4GRY A;  2I5X A;  4YR8 B;  2F6V A;  1C85 A;  1L8K A;  2R0B A;  1PTU A;  2CM2 A;  5K23 A;  2CNE A;  4KYR A;  3QCH A;  1XXV A;  5KAA A;  4R0T A;  3CM3 A;  1T48 A;  4MBB A;  2NLK A;  2JJD A;  3O4S A;  1PXH A;  2I6P A;  2B4O A;  2NZ6 A;  2SHP A;  2NT2 A;  4Y2E A;  1YPT A;  3S3K A;  1Q6M A;  3QCB A;  2I4H A;  5MMZ B;  1YN9 A;  4JBC A;  2PQ5 A;  3QKP A;  4GE6 A;  1AAX A;  3I36 A;  4GS0 A;  3F41 A;  2PA5 A;  3PS5 A;  1WAX A;  4JMJ A;  1RPM A;  2CM3 A;  4ZN5 A;  2G59 A;  2M3V A;  1U25 A;  3MOW A;  1BZC A;  2H4V A;  3O3L A;  2HC2 A;  1LAR A;  2QEP A;  1C84 A;  3SME A;  5KA9 A;  1YTN A;  2Q05 A;  2GP0 A;  4DGX A;  4D3R A;  3S4O A;  1OEO X;  1ONZ A;  1OEU A;  4GFU A; 
#chains in the Genus database with same CATH topology
 2I4E A;  1JLN A;  2HC1 A;  1VHR A;  1YTS A;  2E0T A;  4JNB A;  2I6J A;  4GFV A;  4RHG A;  1NO6 A;  5A5F A;  3EB1 A;  2QDC A;  2GCB A;  2QBR A;  3QCG A;  1RXD A;  2HB1 A;  1ZZW A;  2I6O A;  4ZIY A;  5A5E A;  1G1H A;  2VTD A;  2J17 A;  4BUC A;  2YDU A;  1FGS A;  1PTY A;  1YZ4 A;  2QBQ A;  4CVK A;  1I9S A;  2GC5 A;  3D44 A;  3F9B A;  1ZCL A;  2GCA A;  3BRH A;  4YAA A;  4C12 A;  3QCI A;  3PYZ A;  3ZM0 A;  2CM8 A;  4NYH A;  4BUB A;  3ZM6 A;  1BZJ A;  3S3H A;  3BLT A;  1ECV A;  1G7G A;  1X24 A;  4WTY A;  2HNQ A;  4HJQ A;  1A5Y A;  1JBV A;  3I80 A;  2AM1 A;  5KA2 A;  3V0D A;  3I7Z A;  2CJZ A;  1FQ1 A;  2B4S A;  3O5X A;  1XBO A;  3H2X A;  1ZC0 A;  3QCJ A;  4GRZ A;  3QCN A;  4BPC A;  1Q1M A;  5KAB A;  5K9V A;  4I8N A;  1OEV A;  3ZM1 A;  2F70 A;  3EAX A;  3V0J A;  2PI7 A;  3ZV2 A;  5K25 A;  3V0G A;  3RGQ A;  2P4D A;  1GG4 A;  2RF6 A;  5K9W A;  2GC6 A;  5LXQ B;  1C88 A;  4ZI4 A;  2FH7 A;  4PVG A;  2I3R A;  2ESB A;  3QCL A;  5EHR A;  5HDE A;  1P31 A;  1OHE A;  3EZZ A;  4JMK A;  3RO1 A;  2NV5 A;  2BGE A;  5KA3 A;  2PBN A;  4GWF A;  2AZR A;  3ZMP A;  2Y1O A;  2I3U A;  1WCH A;  4QAP A;  4QF5 A;  2CMC A;  2VOS A;  1ONY A;  2UUP A;  4OHI A;  2PT0 A;  2BZL A;  3S4E A;  3RGO A;  5GTJ A;  3D1H A;  1YWF A;  2AM2 A;  2C7S A;  3A5J A;  2VEU A;  2BV5 A;  1U26 A;  2P6X A;  4OHD A;  1ZCK A;  1U24 A;  2I1Y A;  2H04 A;  2HNP A;  2PSZ A;  1Q6J A;  1XRI A;  2Y2F A;  3F81 A;  4QUM A;  4RI4 A;  1C86 A;  1MKP A;  3D1Q A;  5K24 A;  1O5Z A;  5BZX A;  4RH5 A;  2F71 A;  4GE5 A;  1FPR A;  1JF7 A;  4NX8 A;  1PA1 A;  2BGD A;  4QDI A;  1W7K A;  2HVL A;  1LQF A;  2F6Z A;  4HV4 A;  4ERC A;  1YGR A;  4RKK A;  1NWE A;  4RDD A;  1UAG A;  1I9T A;  2QDP A;  2A8B A;  3F99 A;  3ZM2 A;  3D42 A;  4DGP A;  4H1O A;  1NL9 A;  2QCT A;  2I6I A;  2H4K A;  3UAG A;  1T4J A;  5KA1 A;  4QUN A;  2CMA A;  3BM8 A;  4OHL A;  4HRF A;  2J16 B;  1QZ0 A;  1G1F A;  2WGP A;  4GE2 A;  1KAV A;  3QCF A;  4AZ1 A;  2H4G A;  2VEV A;  3V0F A;  3RZ2 A;  4R30 A;  3BLU A;  3AWF A;  2VEY A;  1YTW A;  5IBS A;  3CWE A;  4UAG A;  4C13 A;  3N0A A;  2Y66 A;  5I6V A;  3OLR A;  2B4U A;  1GFY A;  1E0D A;  1Q6N A;  2CNH A;  2UAG A;  2IMG A;  4D3Q A;  5KA0 A;  4NWG A;  1EEO A;  1Q6S A;  4NND A;  4WOH A;  4D3P A;  1QXK A;  5BX1 A;  1J4X A;  1Q6P A;  2B07 A;  2BIJ A;  2XPC A;  5J8R A;  3SR9 A;  1R6H A;  2Y67 A;  1PYN A;  3O4U A;  1PTV A;  2H03 A;  2NT7 A;  2CM7 A;  2Y68 A;  5AWX A;  1BZH A;  2A3K A;  2I42 A;  3LJ8 A;  1G7F A;  3ZMQ A;  1OET A;  1XM2 A;  2OOQ A;  4OHE A;  3MOZ A;  1OEM X;  2I4G A;  2HCM A;  4J51 A;  4TVV A;  3NME A;  4BJO A;  2VOR A;  2B3O A;  2I75 A;  1PH0 A;  5KA7 A;  1C87 A;  1I57 A;  1OHD A;  5KA4 A;  1PA9 A;  4Z6B A;  1Q6T A;  1T49 A;  4IKC A;  2HY3 A;  4Y14 A;  2FJM A;  3S3F A;  3LK7 A;  4WU2 A;  2F00 A;  3U96 A;  2F46 A;  5KA8 A;  4ICZ A;  4PYH A;  1FPZ A;  2GWO A;  2CNG A;  3OMH A;  3V0I A;  2CNI A;  1V3A A;  3D9C A;  2ZMM A;  2H02 A;  1G1G A;  1PTT A;  1SUG A;  2Y96 A;  1G4U S;  2JFG A;  2XJA A;  1YFO A;  2CNF A;  3QCK A;  2OC3 A;  5M43 A;  2QBS A;  4WU3 A;  4B04 A;  2JFH A;  5EHP A;  3V0E A;  1W78 A;  4ZRT A;  3ZM3 A;  2QBP A;  3S3E A;  2DXP A;  4RI5 A;  2F6T A;  2Q47 A;  5K22 A;  2C46 A;  3D1O A;  1LYV A;  2I6M A;  1XXP A;  1L8G A;  2FJN A;  1GQQ A;  5KAC A;  3B7O A;  1NNY A;  1M3G A;  3QCM A;  2VEW A;  2B4P A;  4HJP A;  3EMU A;  4NWF A;  1G4W R;  1P3D A;  4RH9 A;  3QCD A;  3QCE A;  3O4T A;  3GXH A;  2B49 A;  3M4U A;  1C83 A;  1OES A;  3AWG A;  3F9A A;  2F6W A;  4KYQ A;  4S0G A;  2ZN7 A;  1NZ7 A;  4QAH A;  4QBW A;  1GWZ A;  2X5O A;  2J16 A;  2GJT A;  5BUG A;  1EEN A;  5BZZ A;  1OHC A;  2WJP A;  2OUD A;  2CMB A;  1KAK A;  4H34 A;  2JFF A;  1YGU A;  2NTA A;  5KAD A;  3QKQ A;  2OZ5 A;  3NRS A;  3QCC A;  2CFV A;  3MMJ A;  3V0H A;  2VEX A;  2F6F A;  4QBE A;  3AWE A;  1P15 A;  1WRM A;  1D5R A;  2QDM A;  4KI9 A;  2F6Y A;  4OHH A;  2QCJ A;  3EU0 A;  4R0S A;  5IBM A;  4CVL A;  2HXP A;  1NWL A;  2WTZ A;  2MBC A;  3GXG A;  2G6Z A;  3A5K A;  2AHS A;  4GRY A;  2I5X A;  4YR8 B;  2F6V A;  1C85 A;  1L8K A;  2R0B A;  1PTU A;  2CM2 A;  3HN7 A;  5K23 A;  2CNE A;  4KYR A;  3QCH A;  1XXV A;  5KAA A;  4R0T A;  3CM3 A;  1T48 A;  3MVN A;  4MBB A;  2NLK A;  2JJD A;  1GQY A;  3O4S A;  1PXH A;  2I6P A;  2B4O A;  2NZ6 A;  2SHP A;  2UUO A;  2NT2 A;  4Y2E A;  3QCZ A;  1EEH A;  1YPT A;  3S3K A;  1Q6M A;  3QCB A;  2I4H A;  4CVM A;  5MMZ B;  1YN9 A;  1J6U A;  4JBC A;  2PQ5 A;  3QKP A;  4GE6 A;  1JBW A;  1AAX A;  3I36 A;  4GS0 A;  3F41 A;  2PA5 A;  3PS5 A;  3N2A A;  1WAX A;  4JMJ A;  3ZM5 A;  1RPM A;  2CM3 A;  4ZN5 A;  2G59 A;  2M3V A;  1U25 A;  3MOW A;  1BZC A;  2H4V A;  3ZL8 A;  3O3L A;  2HC2 A;  1LAR A;  2QEP A;  2VTE A;  1C84 A;  3SME A;  5KA9 A;  1YTN A;  2Q05 A;  2GP0 A;  4DGX A;  1E8C A;  4D3R A;  3S4O A;  1OEO X;  1ONZ A;  1OEU A;  4GFU A; 
#chains in the Genus database with same CATH homology
 2I4E A;  1JLN A;  2HC1 A;  1VHR A;  1YTS A;  2E0T A;  4JNB A;  2I6J A;  4GFV A;  4RHG A;  1NO6 A;  3EB1 A;  2QDC A;  2QBR A;  3QCG A;  1RXD A;  2HB1 A;  1ZZW A;  2I6O A;  1G1H A;  2J17 A;  2YDU A;  1PTY A;  1YZ4 A;  2QBQ A;  1I9S A;  3D44 A;  3F9B A;  1ZCL A;  3BRH A;  4YAA A;  3QCI A;  3ZM0 A;  2CM8 A;  4NYH A;  1BZJ A;  3S3H A;  3BLT A;  1ECV A;  1G7G A;  1X24 A;  4WTY A;  2HNQ A;  4HJQ A;  1A5Y A;  3I80 A;  5KA2 A;  3V0D A;  3I7Z A;  2CJZ A;  1FQ1 A;  2B4S A;  3O5X A;  1XBO A;  3H2X A;  1ZC0 A;  3QCJ A;  4GRZ A;  3QCN A;  4BPC A;  1Q1M A;  5KAB A;  5K9V A;  4I8N A;  1OEV A;  3ZM1 A;  2F70 A;  3EAX A;  3V0J A;  2PI7 A;  3ZV2 A;  5K25 A;  3V0G A;  3RGQ A;  2P4D A;  2RF6 A;  5K9W A;  5LXQ B;  1C88 A;  4ZI4 A;  2FH7 A;  4PVG A;  2I3R A;  2ESB A;  3QCL A;  5EHR A;  5HDE A;  1OHE A;  3EZZ A;  4JMK A;  3RO1 A;  2NV5 A;  2BGE A;  5KA3 A;  2PBN A;  4GWF A;  2AZR A;  3ZMP A;  2I3U A;  1WCH A;  4QAP A;  2CMC A;  1ONY A;  4OHI A;  2PT0 A;  2BZL A;  3S4E A;  3RGO A;  5GTJ A;  3D1H A;  1YWF A;  2C7S A;  3A5J A;  2VEU A;  2BV5 A;  1U26 A;  2P6X A;  4OHD A;  1ZCK A;  1U24 A;  2I1Y A;  2H04 A;  2HNP A;  2PSZ A;  1Q6J A;  1XRI A;  2Y2F A;  3F81 A;  4QUM A;  4RI4 A;  1C86 A;  1MKP A;  3D1Q A;  5K24 A;  5BZX A;  4RH5 A;  2F71 A;  4GE5 A;  1FPR A;  1JF7 A;  4NX8 A;  1PA1 A;  2BGD A;  2HVL A;  1LQF A;  2F6Z A;  4ERC A;  1YGR A;  4RKK A;  1NWE A;  4RDD A;  1I9T A;  2QDP A;  2A8B A;  3F99 A;  3ZM2 A;  3D42 A;  4DGP A;  4H1O A;  1NL9 A;  2QCT A;  2I6I A;  2H4K A;  1T4J A;  5KA1 A;  4QUN A;  2CMA A;  3BM8 A;  4OHL A;  4HRF A;  2J16 B;  1QZ0 A;  1G1F A;  2WGP A;  4GE2 A;  1KAV A;  3QCF A;  4AZ1 A;  2H4G A;  2VEV A;  3V0F A;  3RZ2 A;  4R30 A;  3BLU A;  3AWF A;  2VEY A;  1YTW A;  5IBS A;  3CWE A;  3N0A A;  5I6V A;  3OLR A;  2B4U A;  1GFY A;  1Q6N A;  2CNH A;  2IMG A;  4D3Q A;  5KA0 A;  4NWG A;  1EEO A;  1Q6S A;  4NND A;  4WOH A;  4D3P A;  1QXK A;  5BX1 A;  1J4X A;  1Q6P A;  2B07 A;  2BIJ A;  5J8R A;  3SR9 A;  1R6H A;  3O4U A;  1PYN A;  1PTV A;  2H03 A;  2NT7 A;  2CM7 A;  5AWX A;  3LJ8 A;  1BZH A;  2A3K A;  2I42 A;  1G7F A;  3ZMQ A;  1OET A;  1XM2 A;  2OOQ A;  4OHE A;  3MOZ A;  1OEM X;  2I4G A;  2HCM A;  4J51 A;  4TVV A;  3NME A;  4BJO A;  2B3O A;  2I75 A;  1PH0 A;  5KA7 A;  1C87 A;  1I57 A;  1OHD A;  5KA4 A;  1PA9 A;  4Z6B A;  1Q6T A;  1T49 A;  4IKC A;  2HY3 A;  4Y14 A;  2FJM A;  3S3F A;  4WU2 A;  3U96 A;  2F46 A;  5KA8 A;  4ICZ A;  4PYH A;  1FPZ A;  2GWO A;  2CNG A;  3OMH A;  3V0I A;  2CNI A;  1V3A A;  3D9C A;  2ZMM A;  2H02 A;  1G1G A;  1PTT A;  1SUG A;  2Y96 A;  1G4U S;  1YFO A;  2CNF A;  3QCK A;  2OC3 A;  5M43 A;  2QBS A;  4WU3 A;  4B04 A;  5EHP A;  3V0E A;  4ZRT A;  3ZM3 A;  2QBP A;  3S3E A;  2DXP A;  4RI5 A;  2F6T A;  2Q47 A;  5K22 A;  2C46 A;  3D1O A;  1LYV A;  2I6M A;  1XXP A;  1L8G A;  2FJN A;  5KAC A;  3B7O A;  1NNY A;  1M3G A;  3QCM A;  2VEW A;  2B4P A;  4HJP A;  3EMU A;  4NWF A;  1G4W R;  4RH9 A;  3QCD A;  3QCE A;  3O4T A;  3GXH A;  2B49 A;  3M4U A;  1C83 A;  1OES A;  3AWG A;  3F9A A;  2F6W A;  4KYQ A;  4S0G A;  2ZN7 A;  1NZ7 A;  4QAH A;  4QBW A;  1GWZ A;  2J16 A;  2GJT A;  5BUG A;  1EEN A;  5BZZ A;  1OHC A;  2OUD A;  2CMB A;  1KAK A;  4H34 A;  1YGU A;  2NTA A;  5KAD A;  3QKQ A;  2OZ5 A;  3QCC A;  2CFV A;  3MMJ A;  3V0H A;  2VEX A;  2F6F A;  4QBE A;  3AWE A;  1P15 A;  1WRM A;  1D5R A;  2QDM A;  4KI9 A;  2F6Y A;  4OHH A;  2QCJ A;  3EU0 A;  4R0S A;  5IBM A;  2HXP A;  1NWL A;  2MBC A;  3GXG A;  2G6Z A;  3A5K A;  2AHS A;  4GRY A;  2I5X A;  4YR8 B;  2F6V A;  1C85 A;  1L8K A;  2R0B A;  1PTU A;  2CM2 A;  5K23 A;  2CNE A;  4KYR A;  3QCH A;  1XXV A;  5KAA A;  4R0T A;  3CM3 A;  1T48 A;  4MBB A;  2NLK A;  2JJD A;  3O4S A;  1PXH A;  2I6P A;  2B4O A;  2NZ6 A;  2SHP A;  2NT2 A;  4Y2E A;  1YPT A;  3S3K A;  1Q6M A;  3QCB A;  2I4H A;  5MMZ B;  1YN9 A;  4JBC A;  2PQ5 A;  3QKP A;  4GE6 A;  1AAX A;  3I36 A;  4GS0 A;  3F41 A;  2PA5 A;  3PS5 A;  1WAX A;  4JMJ A;  1RPM A;  2CM3 A;  4ZN5 A;  2G59 A;  2M3V A;  1U25 A;  3MOW A;  1BZC A;  2H4V A;  3O3L A;  2HC2 A;  1LAR A;  2QEP A;  1C84 A;  3SME A;  5KA9 A;  1YTN A;  2Q05 A;  2GP0 A;  4DGX A;  4D3R A;  3S4O A;  1OEO X;  1ONZ A;  1OEU A;  4GFU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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