1G7FA

Human ptp1b catalytic domain complexed with pnu177496
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLDMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1
total genus 103
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1g7fA00
2NT7A 3AWGA 1PH0A 2CJZA 2OOQA 5I6VA 3AWEA 2NT2A 2BIJA 1G4US 1G1GA 5KA4A 1T49A 4KYRA 3BLUA 4Y14A 1ZCKA 2OZ5A 2VEVA 5J8RA 1OEMX 3BM8A 2QDMA 1PYNA 2E0TA 4GFUA 3B7OA 4QAHA 1YWFA 1WCHA 4GRYA 4OHEA 4ZN5A 2F71A 3F99A 2CM8A 2GP0A 1L8GA 2I6MA 3QCDA 2PSZA 3F41A 3S3EA 1Q6MA 1ZZWA 2I4GA 5BUGA 3SMEA 4QBWA 2I6IA 2F6FA 2I6PA 2CNGA 2HC1A 2F6VA 2G6ZA 2SHPA 1I9TA 1NWEA 4RI5A 3QCKA 2QBPA 2R0BA 1OHDA 2YDUA 4QUNA 4ICZA 2B49A 4BJOA 1R6HA 3QCIA 1SUGA 4WU2A 3N0AA 3QCEA 2A3KA 2B4OA 3QKQA 1Q6TA 3RGOA 1GFYA 4KI9A 1Q6PA 3F9BA 1ZCLA 3O4SA 2B07A 2I75A 3V0HA 4YR8B 3RZ2A 3GXHA 2H04A 4ERCA 4PVGA 2CNEA 4OHDA 4NWGA 1M3GA 3D1OA 3A5KA 1FPZA 4QUMA 3QCFA 4IKCA 3V0IA 2Q47A 1G7GA 2H02A 1C84A 3CWEA 1FQ1A 1PTYA 3OLRA 3V0EA 5KAAA 1YPTA 2P4DA 4D3PA 1C87A 1RPMA 3EZZA 1PXHA 2M3VA 4HJQA 3S3KA 2H03A 4NWFA 1BZJA 3O4TA 5KADA 1KAKA 3MOZA 2Q05A 1YFOA 1BZCA 4JNBA 2J16B 5EHRA 1XBOA 5GTJA 2QCTA 4JMKA 4OHHA 2PT0A 5IBMA 2CMCA 2G59A 2QDPA 2NZ6A 3S3HA 1KAVA 4GFVA 2VEUA 2B4PA 4GS0A 4DGPA 3I80A 2IMGA 1C86A 5K24A 2J16A 2QBQA 1I9SA 5KA0A 1YZ4A 2HNQA 2J17A 2VEWA 3ZM3A 2OUDA 2WGPA 1U25A 2I6OA 1G1FA 2HC2A 4WU3A 1OETA 2BZLA 3A5JA 4ZRTA 2CMAA 3QCNA 3S3FA 3ZMPA 5KACA 1RXDA 2FJNA 2NV5A 2HB1A 2CNHA 3QCBA 4JMJA 1YGRA 4YAAA 1YN9A 3QCJA 2ZMMA 1V3AA 4JBCA 2CM7A 3ZM1A 3I7ZA 5KA1A 4J51A 2F6ZA 1WRMA 2ESBA 4H1OA 3QCGA 3QCLA 2F6YA 4R30A 2I4EA 2CM2A 3EAXA 4AZ1A 1XM2A 3MMJA 3ZV2A 1G4WR 5K9VA 1D5RA 2QBRA 2C7SA 3ZM0A 4NX8A 3S4OA 2PI7A 1Q6NA 2AHSA 2CMBA 1Q6SA 1OHEA 2A8BA 5KA9A 2BGDA 3SR9A 2I42A 5LXQB 2PQ5A 2RF6A 4TVVA 5M43A 2B3OA 1G1HA 1NO6A 1A5YA 1PA1A 3EMUA 3S4EA 4D3RA 1YTSA 4B04A 2HVLA 1NL9A 1QXKA 1T48A 5KA8A 3PS5A 2VEXA 4R0TA 4Y2EA 3D1QA 3NMEA 3V0DA 3M4UA 2HCMA 2BV5A 2VEYA 4RH9A 3D42A 1QZ0A 4ZI4A 2B4SA 1FPRA 1ZC0A 1C83A 5KABA 4WOHA 5K23A 2CNIA 2GWOA 1OESA 4NNDA 4GE6A 4GE2A 3BLTA 2PBNA 2B4UA 3QCCA 2PA5A 1OEOX 4GE5A 4MBBA 1C85A 2QDCA 3GXGA 3V0JA 4H34A 2I6JA 1G7FA 4NYHA 4PYHA 4Z6BA 2JJDA 5AWXA 3QKPA 1NZ7A 4OHIA 3D44A 3QCMA 3OMHA 4R0SA 2H4VA 1PTUA 3D9CA 2I1YA 3F9AA 1C88A 2I4HA 2I5XA 5KA2A 4D3QA 3MOWA 4RKKA 1Q1MA 3AWFA 5KA7A 1MKPA 2F6TA 2FJMA 2ZN7A 5KA3A 2Y2FA 1WAXA 3O3LA 2H4GA 4HRFA 1YGUA 1XXVA 2HXPA 1GWZA 2CFVA 4GWFA 5MMZB 1OEUA 2QCJA 1JLNA 2FH7A 2QEPA 1X24A 5HDEA 1VHRA 1XXPA 3D1HA 1YTNA 1ECVA 2CM3A 3V0FA 2OC3A 1J4XA 1BZHA 2CNFA 1NWLA 3U96A 2F70A 3RGQA 1Q6JA 3F81A 5K9WA 4S0GA 3CM3A 1U24A 1PTTA 1PTVA 4QBEA 2C46A 3V0GA 2AZRA 3O4UA 2F46A 4OHLA 1U26A 4RDDA 2NLKA 1JF7A 1NNYA 1YTWA 5K25A 3H2XA 1EENA 1I57A 5K22A 2Y96A 2F6WA 1ONYA 3O5XA 5IBSA 2P6XA 4DGXA 3EU0A 4QAPA 3BRHA 3EB1A 4HJPA 1XRIA 1ONZA 2QBSA 3RO1A 4RI4A 1LARA 2NTAA 3ZMQA 5BZXA 1OHCA 2BGEA 2HNPA 5BX1A 1LYVA 2GJTA 3LJ8A 3ZM2A 1PA9A 3I36A 2H4KA 5EHPA 4I8NA 4RH5A 2I3RA 1LQFA 1P15A 3QCHA 4GRZA 1EEOA 1OEVA 4KYQA 1L8KA 5BZZA 4BPCA 2HY3A 2I3UA 2DXPA 1AAXA 1T4JA 4RHGA 4WTYA 2MBCA
chains in the Genus database with same CATH superfamily
2NT7A 3AWGA 1PH0A 2CJZA 2OOQA 5I6VA 3AWEA 2NT2A 2BIJA 5A5EA 1G4US 1G1GA 5KA4A 1T49A 4KYRA 3BLUA 4Y14A 1ZCKA 2OZ5A 2UAGA 2VEVA 5J8RA 1OEMX 3BM8A 2QDMA 1PYNA 2E0TA 4GFUA 3B7OA 4QAHA 1YWFA 1WCHA 4GRYA 4OHEA 4ZN5A 2F71A 3F99A 2CM8A 2GP0A 1J6UA 1L8GA 2I6MA 3QCDA 1JBVA 2PSZA 3F41A 3S3EA 1Q6MA 1ZZWA 2I4GA 5BUGA 1GQQA 2VTDA 3SMEA 4CVKA 4QBWA 2Y1OA 2I6IA 2F6FA 2I6PA 2CNGA 2HC1A 2F6VA 2G6ZA 2Y66A 2SHPA 1I9TA 1NWEA 1EEHA 4RI5A 4C12A 3QCKA 2QBPA 2R0BA 1OHDA 2YDUA 3PYZA 4QUNA 4ICZA 2B49A 4BJOA 1R6HA 3QCIA 1SUGA 4WU2A 3N0AA 3QCEA 2A3KA 2B4OA 3QKQA 4BUCA 4BUBA 1Q6TA 3RGOA 1GFYA 4KI9A 1Q6PA 3F9BA 1ZCLA 3O4SA 2B07A 2I75A 3V0HA 4YR8B 3RZ2A 3GXHA 2H04A 4ERCA 4PVGA 2WTZA 2CNEA 4OHDA 2GC5A 4NWGA 4QF5A 1M3GA 3D1OA 3A5KA 1FPZA 4QUMA 3QCFA 4IKCA 3V0IA 2Q47A 1G7GA 2H02A 1C84A 3CWEA 1FQ1A 1PTYA 3OLRA 3V0EA 5KAAA 1YPTA 2P4DA 4D3PA 1C87A 1RPMA 2XJAA 3EZZA 1PXHA 2M3VA 4HJQA 3S3KA 2H03A 2F00A 4NWFA 1BZJA 3O4TA 2Y68A 5KADA 1KAKA 3MOZA 2Q05A 2AM2A 1YFOA 1BZCA 4JNBA 2J16B 5EHRA 1XBOA 5GTJA 2QCTA 4JMKA 4OHHA 2PT0A 5IBMA 2CMCA 2G59A 2QDPA 2XPCA 2NZ6A 3S3HA 2JFHA 1KAVA 1W7KA 4GFVA 2VEUA 2B4PA 4GS0A 4DGPA 3I80A 2IMGA 1C86A 3MVNA 5K24A 2J16A 2QBQA 1I9SA 5KA0A 1YZ4A 2HNQA 2J17A 2VEWA 3ZL8A 3ZM3A 2OUDA 2WGPA 1U25A 2I6OA 1G1FA 2HC2A 4WU3A 1OETA 2BZLA 4CVMA 3A5JA 4ZRTA 2CMAA 3QCNA 3S3FA 4CVLA 3ZMPA 5KACA 1RXDA 2FJNA 2NV5A 2HB1A 2CNHA 3QCBA 4JMJA 1YGRA 4YAAA 1YN9A 3QCJA 2ZMMA 4UAGA 1P31A 1V3AA 4JBCA 2CM7A 3ZM1A 3I7ZA 5KA1A 4J51A 2F6ZA 1WRMA 2ESBA 4H1OA 1FGSA 3QCGA 3QCLA 2F6YA 4R30A 2I4EA 2CM2A 3EAXA 4AZ1A 1XM2A 3MMJA 3ZV2A 1G4WR 5K9VA 1D5RA 2GCAA 2QBRA 2C7SA 3ZM0A 4NX8A 3S4OA 2PI7A 1Q6NA 2AHSA 2CMBA 1Q6SA 1OHEA 2A8BA 5KA9A 2BGDA 3SR9A 1O5ZA 2I42A 5LXQB 2JFFA 3LK7A 2PQ5A 2RF6A 4TVVA 5M43A 2B3OA 1G1HA 1NO6A 1A5YA 1PA1A 3EMUA 3S4EA 4D3RA 1YTSA 4B04A 2HVLA 1NL9A 1GQYA 1QXKA 1T48A 5KA8A 3N2AA 2VEXA 3PS5A 4R0TA 4Y2EA 3D1QA 3NMEA 3V0DA 3M4UA 2HCMA 2BV5A 2VEYA 2VOSA 4RH9A 3D42A 3ZM5A 1QZ0A 4ZI4A 3HN7A 2B4SA 1FPRA 1ZC0A 1C83A 5KABA 4WOHA 5K23A 2CNIA 2GWOA 1OESA 4NNDA 4GE6A 4GE2A 3BLTA 2PBNA 2B4UA 3QCCA 2PA5A 1OEOX 4GE5A 4MBBA 1C85A 2QDCA 3GXGA 3V0JA 4H34A 2I6JA 1G7FA 4NYHA 4PYHA 1GG4A 4Z6BA 2JJDA 3QCZA 5AWXA 3QKPA 4ZIYA 1NZ7A 4OHIA 3D44A 3QCMA 3OMHA 4R0SA 2H4VA 1E8CA 1PTUA 3D9CA 2I1YA 3F9AA 1C88A 4HV4A 2I4HA 2I5XA 5KA2A 4D3QA 3MOWA 4RKKA 1Q1MA 3AWFA 5KA7A 1MKPA 2F6TA 2FJMA 2ZN7A 5KA3A 2Y2FA 1WAXA 3O3LA 2H4GA 4HRFA 1YGUA 1XXVA 3ZM6A 2HXPA 1GWZA 2CFVA 4GWFA 5MMZB 1OEUA 2QCJA 1JLNA 2JFGA 2FH7A 2QEPA 3UAGA 1X24A 5HDEA 2VTEA 1VHRA 1XXPA 3D1HA 1YTNA 1ECVA 2CM3A 3V0FA 2OC3A 1J4XA 1BZHA 2CNFA 1NWLA 3U96A 1P3DA 5A5FA 2F70A 3RGQA 1Q6JA 3F81A 2GC6A 5K9WA 4S0GA 3CM3A 1U24A 1JBWA 1PTTA 1PTVA 4QBEA 2C46A 3V0GA 2AZRA 1E0DA 2WJPA 3O4UA 2UUOA 2F46A 4C13A 4OHLA 1U26A 4RDDA 2NLKA 1JF7A 1NNYA 1YTWA 2UUPA 5K25A 3H2XA 1EENA 2GCBA 1I57A 5K22A 2Y96A 2VORA 2F6WA 1ONYA 3O5XA 5IBSA 2P6XA 4DGXA 3EU0A 4QAPA 3BRHA 3EB1A 4HJPA 1XRIA 1ONZA 2QBSA 2X5OA 3RO1A 4RI4A 1LARA 2NTAA 2Y67A 3ZMQA 5BZXA 1W78A 1OHCA 2BGEA 4QDIA 2HNPA 5BX1A 1LYVA 2GJTA 3LJ8A 3ZM2A 1PA9A 3I36A 2H4KA 5EHPA 4I8NA 4RH5A 2I3RA 1LQFA 1P15A 3QCHA 4GRZA 1UAGA 1EEOA 1OEVA 4KYQA 1L8KA 5BZZA 4BPCA 3NRSA 2HY3A 2I3UA 2DXPA 1AAXA 1T4JA 4RHGA 2AM1A 4WTYA 2MBCA
chains in the Genus database with same CATH topology
2NT7A 3AWGA 1PH0A 2CJZA 2OOQA 5I6VA 3AWEA 2NT2A 2BIJA 1G4US 1G1GA 5KA4A 1T49A 4KYRA 3BLUA 4Y14A 1ZCKA 2OZ5A 2VEVA 5J8RA 1OEMX 3BM8A 2QDMA 1PYNA 2E0TA 4GFUA 3B7OA 4QAHA 1YWFA 1WCHA 4GRYA 4OHEA 4ZN5A 2F71A 3F99A 2CM8A 2GP0A 1L8GA 2I6MA 3QCDA 2PSZA 3F41A 3S3EA 1Q6MA 1ZZWA 2I4GA 5BUGA 3SMEA 4QBWA 2I6IA 2F6FA 2I6PA 2CNGA 2HC1A 2F6VA 2G6ZA 2SHPA 1I9TA 1NWEA 4RI5A 3QCKA 2QBPA 2R0BA 1OHDA 2YDUA 4QUNA 4ICZA 2B49A 4BJOA 1R6HA 3QCIA 1SUGA 4WU2A 3N0AA 3QCEA 2A3KA 2B4OA 3QKQA 1Q6TA 3RGOA 1GFYA 4KI9A 1Q6PA 3F9BA 1ZCLA 3O4SA 2B07A 2I75A 3V0HA 4YR8B 3RZ2A 3GXHA 2H04A 4ERCA 4PVGA 2CNEA 4OHDA 4NWGA 1M3GA 3D1OA 3A5KA 1FPZA 4QUMA 3QCFA 4IKCA 3V0IA 2Q47A 1G7GA 2H02A 1C84A 3CWEA 1FQ1A 1PTYA 3OLRA 3V0EA 5KAAA 1YPTA 2P4DA 4D3PA 1C87A 1RPMA 3EZZA 1PXHA 2M3VA 4HJQA 3S3KA 2H03A 4NWFA 1BZJA 3O4TA 5KADA 1KAKA 3MOZA 2Q05A 1YFOA 1BZCA 4JNBA 2J16B 5EHRA 1XBOA 5GTJA 2QCTA 4JMKA 4OHHA 2PT0A 5IBMA 2CMCA 2G59A 2QDPA 2NZ6A 3S3HA 1KAVA 4GFVA 2VEUA 2B4PA 4GS0A 4DGPA 3I80A 2IMGA 1C86A 5K24A 2J16A 2QBQA 1I9SA 5KA0A 1YZ4A 2HNQA 2J17A 2VEWA 3ZM3A 2OUDA 2WGPA 1U25A 2I6OA 1G1FA 2HC2A 4WU3A 1OETA 2BZLA 3A5JA 4ZRTA 2CMAA 3QCNA 3S3FA 3ZMPA 5KACA 1RXDA 2FJNA 2NV5A 2HB1A 2CNHA 3QCBA 4JMJA 1YGRA 4YAAA 1YN9A 3QCJA 2ZMMA 1V3AA 4JBCA 2CM7A 3ZM1A 3I7ZA 5KA1A 4J51A 2F6ZA 1WRMA 2ESBA 4H1OA 3QCGA 3QCLA 2F6YA 4R30A 2I4EA 2CM2A 3EAXA 4AZ1A 1XM2A 3MMJA 3ZV2A 1G4WR 5K9VA 1D5RA 2QBRA 2C7SA 3ZM0A 4NX8A 3S4OA 2PI7A 1Q6NA 2AHSA 2CMBA 1Q6SA 1OHEA 2A8BA 5KA9A 2BGDA 3SR9A 2I42A 5LXQB 2PQ5A 2RF6A 4TVVA 5M43A 2B3OA 1G1HA 1NO6A 1A5YA 1PA1A 3EMUA 3S4EA 4D3RA 1YTSA 4B04A 2HVLA 1NL9A 1QXKA 1T48A 5KA8A 3PS5A 2VEXA 4R0TA 4Y2EA 3D1QA 3NMEA 3V0DA 3M4UA 2HCMA 2BV5A 2VEYA 4RH9A 3D42A 1QZ0A 4ZI4A 2B4SA 1FPRA 1ZC0A 1C83A 5KABA 4WOHA 5K23A 2CNIA 2GWOA 1OESA 4NNDA 4GE6A 4GE2A 3BLTA 2PBNA 2B4UA 3QCCA 2PA5A 1OEOX 4GE5A 4MBBA 1C85A 2QDCA 3GXGA 3V0JA 4H34A 2I6JA 1G7FA 4NYHA 4PYHA 4Z6BA 2JJDA 5AWXA 3QKPA 1NZ7A 4OHIA 3D44A 3QCMA 3OMHA 4R0SA 2H4VA 1PTUA 3D9CA 2I1YA 3F9AA 1C88A 2I4HA 2I5XA 5KA2A 4D3QA 3MOWA 4RKKA 1Q1MA 3AWFA 5KA7A 1MKPA 2F6TA 2FJMA 2ZN7A 5KA3A 2Y2FA 1WAXA 3O3LA 2H4GA 4HRFA 1YGUA 1XXVA 2HXPA 1GWZA 2CFVA 4GWFA 5MMZB 1OEUA 2QCJA 1JLNA 2FH7A 2QEPA 1X24A 5HDEA 1VHRA 1XXPA 3D1HA 1YTNA 1ECVA 2CM3A 3V0FA 2OC3A 1J4XA 1BZHA 2CNFA 1NWLA 3U96A 2F70A 3RGQA 1Q6JA 3F81A 5K9WA 4S0GA 3CM3A 1U24A 1PTTA 1PTVA 4QBEA 2C46A 3V0GA 2AZRA 3O4UA 2F46A 4OHLA 1U26A 4RDDA 2NLKA 1JF7A 1NNYA 1YTWA 5K25A 3H2XA 1EENA 1I57A 5K22A 2Y96A 2F6WA 1ONYA 3O5XA 5IBSA 2P6XA 4DGXA 3EU0A 4QAPA 3BRHA 3EB1A 4HJPA 1XRIA 1ONZA 2QBSA 3RO1A 4RI4A 1LARA 2NTAA 3ZMQA 5BZXA 1OHCA 2BGEA 2HNPA 5BX1A 1LYVA 2GJTA 3LJ8A 3ZM2A 1PA9A 3I36A 2H4KA 5EHPA 4I8NA 4RH5A 2I3RA 1LQFA 1P15A 3QCHA 4GRZA 1EEOA 1OEVA 4KYQA 1L8KA 5BZZA 4BPCA 2HY3A 2I3UA 2DXPA 1AAXA 1T4JA 4RHGA 4WTYA 2MBCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NT7 A;  3AWG A;  1PH0 A;  2CJZ A;  2OOQ A;  5I6V A;  3AWE A;  2NT2 A;  2BIJ A;  1G4U S;  1G1G A;  5KA4 A;  1T49 A;  4KYR A;  3BLU A;  4Y14 A;  1ZCK A;  2OZ5 A;  2VEV A;  5J8R A;  1OEM X;  3BM8 A;  2QDM A;  1PYN A;  2E0T A;  4GFU A;  3B7O A;  4QAH A;  1YWF A;  1WCH A;  4GRY A;  4OHE A;  4ZN5 A;  2F71 A;  3F99 A;  2CM8 A;  2GP0 A;  1L8G A;  2I6M A;  3QCD A;  2PSZ A;  3F41 A;  3S3E A;  1Q6M A;  1ZZW A;  2I4G A;  5BUG A;  3SME A;  4QBW A;  2I6I A;  2F6F A;  2I6P A;  2CNG A;  2HC1 A;  2F6V A;  2G6Z A;  2SHP A;  1I9T A;  1NWE A;  4RI5 A;  3QCK A;  2QBP A;  2R0B A;  1OHD A;  2YDU A;  4QUN A;  4ICZ A;  2B49 A;  4BJO A;  1R6H A;  3QCI A;  1SUG A;  4WU2 A;  3N0A A;  3QCE A;  2A3K A;  2B4O A;  3QKQ A;  1Q6T A;  3RGO A;  1GFY A;  4KI9 A;  1Q6P A;  3F9B A;  1ZCL A;  3O4S A;  2B07 A;  2I75 A;  3V0H A;  4YR8 B;  3RZ2 A;  3GXH A;  2H04 A;  4ERC A;  4PVG A;  2CNE A;  4OHD A;  4NWG A;  1M3G A;  3D1O A;  3A5K A;  1FPZ A;  4QUM A;  3QCF A;  4IKC A;  3V0I A;  2Q47 A;  1G7G A;  2H02 A;  1C84 A;  3CWE A;  1FQ1 A;  1PTY A;  3OLR A;  3V0E A;  5KAA A;  1YPT A;  2P4D A;  4D3P A;  1C87 A;  1RPM A;  3EZZ A;  1PXH A;  2M3V A;  4HJQ A;  3S3K A;  2H03 A;  4NWF A;  1BZJ A;  3O4T A;  5KAD A;  1KAK A;  3MOZ A;  2Q05 A;  1YFO A;  1BZC A;  4JNB A;  2J16 B;  5EHR A;  1XBO A;  5GTJ A;  2QCT A;  4JMK A;  4OHH A;  2PT0 A;  5IBM A;  2CMC A;  2G59 A;  2QDP A;  2NZ6 A;  3S3H A;  1KAV A;  4GFV A;  2VEU A;  2B4P A;  4GS0 A;  4DGP A;  3I80 A;  2IMG A;  1C86 A;  5K24 A;  2J16 A;  2QBQ A;  1I9S A;  5KA0 A;  1YZ4 A;  2HNQ A;  2J17 A;  2VEW A;  3ZM3 A;  2OUD A;  2WGP A;  1U25 A;  2I6O A;  1G1F A;  2HC2 A;  4WU3 A;  1OET A;  2BZL A;  3A5J A;  4ZRT A;  2CMA A;  3QCN A;  3S3F A;  3ZMP A;  5KAC A;  1RXD A;  2FJN A;  2NV5 A;  2HB1 A;  2CNH A;  3QCB A;  4JMJ A;  1YGR A;  4YAA A;  1YN9 A;  3QCJ A;  2ZMM A;  1V3A A;  4JBC A;  2CM7 A;  3ZM1 A;  3I7Z A;  5KA1 A;  4J51 A;  2F6Z A;  1WRM A;  2ESB A;  4H1O A;  3QCG A;  3QCL A;  2F6Y A;  4R30 A;  2I4E A;  2CM2 A;  3EAX A;  4AZ1 A;  1XM2 A;  3MMJ A;  3ZV2 A;  1G4W R;  5K9V A;  1D5R A;  2QBR A;  2C7S A;  3ZM0 A;  4NX8 A;  3S4O A;  2PI7 A;  1Q6N A;  2AHS A;  2CMB A;  1Q6S A;  1OHE A;  2A8B A;  5KA9 A;  2BGD A;  3SR9 A;  2I42 A;  5LXQ B;  2PQ5 A;  2RF6 A;  4TVV A;  5M43 A;  2B3O A;  1G1H A;  1NO6 A;  1A5Y A;  1PA1 A;  3EMU A;  3S4E A;  4D3R A;  1YTS A;  4B04 A;  2HVL A;  1NL9 A;  1QXK A;  1T48 A;  5KA8 A;  3PS5 A;  2VEX A;  4R0T A;  4Y2E A;  3D1Q A;  3NME A;  3V0D A;  3M4U A;  2HCM A;  2BV5 A;  2VEY A;  4RH9 A;  3D42 A;  1QZ0 A;  4ZI4 A;  2B4S A;  1FPR A;  1ZC0 A;  1C83 A;  5KAB A;  4WOH A;  5K23 A;  2CNI A;  2GWO A;  1OES A;  4NND A;  4GE6 A;  4GE2 A;  3BLT A;  2PBN A;  2B4U A;  3QCC A;  2PA5 A;  1OEO X;  4GE5 A;  4MBB A;  1C85 A;  2QDC A;  3GXG A;  3V0J A;  4H34 A;  2I6J A;  1G7F A;  4NYH A;  4PYH A;  4Z6B A;  2JJD A;  5AWX A;  3QKP A;  1NZ7 A;  4OHI A;  3D44 A;  3QCM A;  3OMH A;  4R0S A;  2H4V A;  1PTU A;  3D9C A;  2I1Y A;  3F9A A;  1C88 A;  2I4H A;  2I5X A;  5KA2 A;  4D3Q A;  3MOW A;  4RKK A;  1Q1M A;  3AWF A;  5KA7 A;  1MKP A;  2F6T A;  2FJM A;  2ZN7 A;  5KA3 A;  2Y2F A;  1WAX A;  3O3L A;  2H4G A;  4HRF A;  1YGU A;  1XXV A;  2HXP A;  1GWZ A;  2CFV A;  4GWF A;  5MMZ B;  1OEU A;  2QCJ A;  1JLN A;  2FH7 A;  2QEP A;  1X24 A;  5HDE A;  1VHR A;  1XXP A;  3D1H A;  1YTN A;  1ECV A;  2CM3 A;  3V0F A;  2OC3 A;  1J4X A;  1BZH A;  2CNF A;  1NWL A;  3U96 A;  2F70 A;  3RGQ A;  1Q6J A;  3F81 A;  5K9W A;  4S0G A;  3CM3 A;  1U24 A;  1PTT A;  1PTV A;  4QBE A;  2C46 A;  3V0G A;  2AZR A;  3O4U A;  2F46 A;  4OHL A;  1U26 A;  4RDD A;  2NLK A;  1JF7 A;  1NNY A;  1YTW A;  5K25 A;  3H2X A;  1EEN A;  1I57 A;  5K22 A;  2Y96 A;  2F6W A;  1ONY A;  3O5X A;  5IBS A;  2P6X A;  4DGX A;  3EU0 A;  4QAP A;  3BRH A;  3EB1 A;  4HJP A;  1XRI A;  1ONZ A;  2QBS A;  3RO1 A;  4RI4 A;  1LAR A;  2NTA A;  3ZMQ A;  5BZX A;  1OHC A;  2BGE A;  2HNP A;  5BX1 A;  1LYV A;  2GJT A;  3LJ8 A;  3ZM2 A;  1PA9 A;  3I36 A;  2H4K A;  5EHP A;  4I8N A;  4RH5 A;  2I3R A;  1LQF A;  1P15 A;  3QCH A;  4GRZ A;  1EEO A;  1OEV A;  4KYQ A;  1L8K A;  5BZZ A;  4BPC A;  2HY3 A;  2I3U A;  2DXP A;  1AAX A;  1T4J A;  4RHG A;  4WTY A;  2MBC A; 
#chains in the Genus database with same CATH topology
 2NT7 A;  3AWG A;  1PH0 A;  2CJZ A;  2OOQ A;  5I6V A;  3AWE A;  2NT2 A;  2BIJ A;  5A5E A;  1G4U S;  1G1G A;  5KA4 A;  1T49 A;  4KYR A;  3BLU A;  4Y14 A;  1ZCK A;  2OZ5 A;  2UAG A;  2VEV A;  5J8R A;  1OEM X;  3BM8 A;  2QDM A;  1PYN A;  2E0T A;  4GFU A;  3B7O A;  4QAH A;  1YWF A;  1WCH A;  4GRY A;  4OHE A;  4ZN5 A;  2F71 A;  3F99 A;  2CM8 A;  2GP0 A;  1J6U A;  1L8G A;  2I6M A;  3QCD A;  1JBV A;  2PSZ A;  3F41 A;  3S3E A;  1Q6M A;  1ZZW A;  2I4G A;  5BUG A;  1GQQ A;  2VTD A;  3SME A;  4CVK A;  4QBW A;  2Y1O A;  2I6I A;  2F6F A;  2I6P A;  2CNG A;  2HC1 A;  2F6V A;  2G6Z A;  2Y66 A;  2SHP A;  1I9T A;  1NWE A;  1EEH A;  4RI5 A;  4C12 A;  3QCK A;  2QBP A;  2R0B A;  1OHD A;  2YDU A;  3PYZ A;  4QUN A;  4ICZ A;  2B49 A;  4BJO A;  1R6H A;  3QCI A;  1SUG A;  4WU2 A;  3N0A A;  3QCE A;  2A3K A;  2B4O A;  3QKQ A;  4BUC A;  4BUB A;  1Q6T A;  3RGO A;  1GFY A;  4KI9 A;  1Q6P A;  3F9B A;  1ZCL A;  3O4S A;  2B07 A;  2I75 A;  3V0H A;  4YR8 B;  3RZ2 A;  3GXH A;  2H04 A;  4ERC A;  4PVG A;  2WTZ A;  2CNE A;  4OHD A;  2GC5 A;  4NWG A;  4QF5 A;  1M3G A;  3D1O A;  3A5K A;  1FPZ A;  4QUM A;  3QCF A;  4IKC A;  3V0I A;  2Q47 A;  1G7G A;  2H02 A;  1C84 A;  3CWE A;  1FQ1 A;  1PTY A;  3OLR A;  3V0E A;  5KAA A;  1YPT A;  2P4D A;  4D3P A;  1C87 A;  1RPM A;  2XJA A;  3EZZ A;  1PXH A;  2M3V A;  4HJQ A;  3S3K A;  2H03 A;  2F00 A;  4NWF A;  1BZJ A;  3O4T A;  2Y68 A;  5KAD A;  1KAK A;  3MOZ A;  2Q05 A;  2AM2 A;  1YFO A;  1BZC A;  4JNB A;  2J16 B;  5EHR A;  1XBO A;  5GTJ A;  2QCT A;  4JMK A;  4OHH A;  2PT0 A;  5IBM A;  2CMC A;  2G59 A;  2QDP A;  2XPC A;  2NZ6 A;  3S3H A;  2JFH A;  1KAV A;  1W7K A;  4GFV A;  2VEU A;  2B4P A;  4GS0 A;  4DGP A;  3I80 A;  2IMG A;  1C86 A;  3MVN A;  5K24 A;  2J16 A;  2QBQ A;  1I9S A;  5KA0 A;  1YZ4 A;  2HNQ A;  2J17 A;  2VEW A;  3ZL8 A;  3ZM3 A;  2OUD A;  2WGP A;  1U25 A;  2I6O A;  1G1F A;  2HC2 A;  4WU3 A;  1OET A;  2BZL A;  4CVM A;  3A5J A;  4ZRT A;  2CMA A;  3QCN A;  3S3F A;  4CVL A;  3ZMP A;  5KAC A;  1RXD A;  2FJN A;  2NV5 A;  2HB1 A;  2CNH A;  3QCB A;  4JMJ A;  1YGR A;  4YAA A;  1YN9 A;  3QCJ A;  2ZMM A;  4UAG A;  1P31 A;  1V3A A;  4JBC A;  2CM7 A;  3ZM1 A;  3I7Z A;  5KA1 A;  4J51 A;  2F6Z A;  1WRM A;  2ESB A;  4H1O A;  1FGS A;  3QCG A;  3QCL A;  2F6Y A;  4R30 A;  2I4E A;  2CM2 A;  3EAX A;  4AZ1 A;  1XM2 A;  3MMJ A;  3ZV2 A;  1G4W R;  5K9V A;  1D5R A;  2GCA A;  2QBR A;  2C7S A;  3ZM0 A;  4NX8 A;  3S4O A;  2PI7 A;  1Q6N A;  2AHS A;  2CMB A;  1Q6S A;  1OHE A;  2A8B A;  5KA9 A;  2BGD A;  3SR9 A;  1O5Z A;  2I42 A;  5LXQ B;  2JFF A;  3LK7 A;  2PQ5 A;  2RF6 A;  4TVV A;  5M43 A;  2B3O A;  1G1H A;  1NO6 A;  1A5Y A;  1PA1 A;  3EMU A;  3S4E A;  4D3R A;  1YTS A;  4B04 A;  2HVL A;  1NL9 A;  1GQY A;  1QXK A;  1T48 A;  5KA8 A;  3N2A A;  2VEX A;  3PS5 A;  4R0T A;  4Y2E A;  3D1Q A;  3NME A;  3V0D A;  3M4U A;  2HCM A;  2BV5 A;  2VEY A;  2VOS A;  4RH9 A;  3D42 A;  3ZM5 A;  1QZ0 A;  4ZI4 A;  3HN7 A;  2B4S A;  1FPR A;  1ZC0 A;  1C83 A;  5KAB A;  4WOH A;  5K23 A;  2CNI A;  2GWO A;  1OES A;  4NND A;  4GE6 A;  4GE2 A;  3BLT A;  2PBN A;  2B4U A;  3QCC A;  2PA5 A;  1OEO X;  4GE5 A;  4MBB A;  1C85 A;  2QDC A;  3GXG A;  3V0J A;  4H34 A;  2I6J A;  1G7F A;  4NYH A;  4PYH A;  1GG4 A;  4Z6B A;  2JJD A;  3QCZ A;  5AWX A;  3QKP A;  4ZIY A;  1NZ7 A;  4OHI A;  3D44 A;  3QCM A;  3OMH A;  4R0S A;  2H4V A;  1E8C A;  1PTU A;  3D9C A;  2I1Y A;  3F9A A;  1C88 A;  4HV4 A;  2I4H A;  2I5X A;  5KA2 A;  4D3Q A;  3MOW A;  4RKK A;  1Q1M A;  3AWF A;  5KA7 A;  1MKP A;  2F6T A;  2FJM A;  2ZN7 A;  5KA3 A;  2Y2F A;  1WAX A;  3O3L A;  2H4G A;  4HRF A;  1YGU A;  1XXV A;  3ZM6 A;  2HXP A;  1GWZ A;  2CFV A;  4GWF A;  5MMZ B;  1OEU A;  2QCJ A;  1JLN A;  2JFG A;  2FH7 A;  2QEP A;  3UAG A;  1X24 A;  5HDE A;  2VTE A;  1VHR A;  1XXP A;  3D1H A;  1YTN A;  1ECV A;  2CM3 A;  3V0F A;  2OC3 A;  1J4X A;  1BZH A;  2CNF A;  1NWL A;  3U96 A;  1P3D A;  5A5F A;  2F70 A;  3RGQ A;  1Q6J A;  3F81 A;  2GC6 A;  5K9W A;  4S0G A;  3CM3 A;  1U24 A;  1JBW A;  1PTT A;  1PTV A;  4QBE A;  2C46 A;  3V0G A;  2AZR A;  1E0D A;  2WJP A;  3O4U A;  2UUO A;  2F46 A;  4C13 A;  4OHL A;  1U26 A;  4RDD A;  2NLK A;  1JF7 A;  1NNY A;  1YTW A;  2UUP A;  5K25 A;  3H2X A;  1EEN A;  2GCB A;  1I57 A;  5K22 A;  2Y96 A;  2VOR A;  2F6W A;  1ONY A;  3O5X A;  5IBS A;  2P6X A;  4DGX A;  3EU0 A;  4QAP A;  3BRH A;  3EB1 A;  4HJP A;  1XRI A;  1ONZ A;  2QBS A;  2X5O A;  3RO1 A;  4RI4 A;  1LAR A;  2NTA A;  2Y67 A;  3ZMQ A;  5BZX A;  1W78 A;  1OHC A;  2BGE A;  4QDI A;  2HNP A;  5BX1 A;  1LYV A;  2GJT A;  3LJ8 A;  3ZM2 A;  1PA9 A;  3I36 A;  2H4K A;  5EHP A;  4I8N A;  4RH5 A;  2I3R A;  1LQF A;  1P15 A;  3QCH A;  4GRZ A;  1UAG A;  1EEO A;  1OEV A;  4KYQ A;  1L8K A;  5BZZ A;  4BPC A;  3NRS A;  2HY3 A;  2I3U A;  2DXP A;  1AAX A;  1T4J A;  4RHG A;  2AM1 A;  4WTY A;  2MBC A; 
#chains in the Genus database with same CATH homology
 2NT7 A;  3AWG A;  1PH0 A;  2CJZ A;  2OOQ A;  5I6V A;  3AWE A;  2NT2 A;  2BIJ A;  1G4U S;  1G1G A;  5KA4 A;  1T49 A;  4KYR A;  3BLU A;  4Y14 A;  1ZCK A;  2OZ5 A;  2VEV A;  5J8R A;  1OEM X;  3BM8 A;  2QDM A;  1PYN A;  2E0T A;  4GFU A;  3B7O A;  4QAH A;  1YWF A;  1WCH A;  4GRY A;  4OHE A;  4ZN5 A;  2F71 A;  3F99 A;  2CM8 A;  2GP0 A;  1L8G A;  2I6M A;  3QCD A;  2PSZ A;  3F41 A;  3S3E A;  1Q6M A;  1ZZW A;  2I4G A;  5BUG A;  3SME A;  4QBW A;  2I6I A;  2F6F A;  2I6P A;  2CNG A;  2HC1 A;  2F6V A;  2G6Z A;  2SHP A;  1I9T A;  1NWE A;  4RI5 A;  3QCK A;  2QBP A;  2R0B A;  1OHD A;  2YDU A;  4QUN A;  4ICZ A;  2B49 A;  4BJO A;  1R6H A;  3QCI A;  1SUG A;  4WU2 A;  3N0A A;  3QCE A;  2A3K A;  2B4O A;  3QKQ A;  1Q6T A;  3RGO A;  1GFY A;  4KI9 A;  1Q6P A;  3F9B A;  1ZCL A;  3O4S A;  2B07 A;  2I75 A;  3V0H A;  4YR8 B;  3RZ2 A;  3GXH A;  2H04 A;  4ERC A;  4PVG A;  2CNE A;  4OHD A;  4NWG A;  1M3G A;  3D1O A;  3A5K A;  1FPZ A;  4QUM A;  3QCF A;  4IKC A;  3V0I A;  2Q47 A;  1G7G A;  2H02 A;  1C84 A;  3CWE A;  1FQ1 A;  1PTY A;  3OLR A;  3V0E A;  5KAA A;  1YPT A;  2P4D A;  4D3P A;  1C87 A;  1RPM A;  3EZZ A;  1PXH A;  2M3V A;  4HJQ A;  3S3K A;  2H03 A;  4NWF A;  1BZJ A;  3O4T A;  5KAD A;  1KAK A;  3MOZ A;  2Q05 A;  1YFO A;  1BZC A;  4JNB A;  2J16 B;  5EHR A;  1XBO A;  5GTJ A;  2QCT A;  4JMK A;  4OHH A;  2PT0 A;  5IBM A;  2CMC A;  2G59 A;  2QDP A;  2NZ6 A;  3S3H A;  1KAV A;  4GFV A;  2VEU A;  2B4P A;  4GS0 A;  4DGP A;  3I80 A;  2IMG A;  1C86 A;  5K24 A;  2J16 A;  2QBQ A;  1I9S A;  5KA0 A;  1YZ4 A;  2HNQ A;  2J17 A;  2VEW A;  3ZM3 A;  2OUD A;  2WGP A;  1U25 A;  2I6O A;  1G1F A;  2HC2 A;  4WU3 A;  1OET A;  2BZL A;  3A5J A;  4ZRT A;  2CMA A;  3QCN A;  3S3F A;  3ZMP A;  5KAC A;  1RXD A;  2FJN A;  2NV5 A;  2HB1 A;  2CNH A;  3QCB A;  4JMJ A;  1YGR A;  4YAA A;  1YN9 A;  3QCJ A;  2ZMM A;  1V3A A;  4JBC A;  2CM7 A;  3ZM1 A;  3I7Z A;  5KA1 A;  4J51 A;  2F6Z A;  1WRM A;  2ESB A;  4H1O A;  3QCG A;  3QCL A;  2F6Y A;  4R30 A;  2I4E A;  2CM2 A;  3EAX A;  4AZ1 A;  1XM2 A;  3MMJ A;  3ZV2 A;  1G4W R;  5K9V A;  1D5R A;  2QBR A;  2C7S A;  3ZM0 A;  4NX8 A;  3S4O A;  2PI7 A;  1Q6N A;  2AHS A;  2CMB A;  1Q6S A;  1OHE A;  2A8B A;  5KA9 A;  2BGD A;  3SR9 A;  2I42 A;  5LXQ B;  2PQ5 A;  2RF6 A;  4TVV A;  5M43 A;  2B3O A;  1G1H A;  1NO6 A;  1A5Y A;  1PA1 A;  3EMU A;  3S4E A;  4D3R A;  1YTS A;  4B04 A;  2HVL A;  1NL9 A;  1QXK A;  1T48 A;  5KA8 A;  3PS5 A;  2VEX A;  4R0T A;  4Y2E A;  3D1Q A;  3NME A;  3V0D A;  3M4U A;  2HCM A;  2BV5 A;  2VEY A;  4RH9 A;  3D42 A;  1QZ0 A;  4ZI4 A;  2B4S A;  1FPR A;  1ZC0 A;  1C83 A;  5KAB A;  4WOH A;  5K23 A;  2CNI A;  2GWO A;  1OES A;  4NND A;  4GE6 A;  4GE2 A;  3BLT A;  2PBN A;  2B4U A;  3QCC A;  2PA5 A;  1OEO X;  4GE5 A;  4MBB A;  1C85 A;  2QDC A;  3GXG A;  3V0J A;  4H34 A;  2I6J A;  1G7F A;  4NYH A;  4PYH A;  4Z6B A;  2JJD A;  5AWX A;  3QKP A;  1NZ7 A;  4OHI A;  3D44 A;  3QCM A;  3OMH A;  4R0S A;  2H4V A;  1PTU A;  3D9C A;  2I1Y A;  3F9A A;  1C88 A;  2I4H A;  2I5X A;  5KA2 A;  4D3Q A;  3MOW A;  4RKK A;  1Q1M A;  3AWF A;  5KA7 A;  1MKP A;  2F6T A;  2FJM A;  2ZN7 A;  5KA3 A;  2Y2F A;  1WAX A;  3O3L A;  2H4G A;  4HRF A;  1YGU A;  1XXV A;  2HXP A;  1GWZ A;  2CFV A;  4GWF A;  5MMZ B;  1OEU A;  2QCJ A;  1JLN A;  2FH7 A;  2QEP A;  1X24 A;  5HDE A;  1VHR A;  1XXP A;  3D1H A;  1YTN A;  1ECV A;  2CM3 A;  3V0F A;  2OC3 A;  1J4X A;  1BZH A;  2CNF A;  1NWL A;  3U96 A;  2F70 A;  3RGQ A;  1Q6J A;  3F81 A;  5K9W A;  4S0G A;  3CM3 A;  1U24 A;  1PTT A;  1PTV A;  4QBE A;  2C46 A;  3V0G A;  2AZR A;  3O4U A;  2F46 A;  4OHL A;  1U26 A;  4RDD A;  2NLK A;  1JF7 A;  1NNY A;  1YTW A;  5K25 A;  3H2X A;  1EEN A;  1I57 A;  5K22 A;  2Y96 A;  2F6W A;  1ONY A;  3O5X A;  5IBS A;  2P6X A;  4DGX A;  3EU0 A;  4QAP A;  3BRH A;  3EB1 A;  4HJP A;  1XRI A;  1ONZ A;  2QBS A;  3RO1 A;  4RI4 A;  1LAR A;  2NTA A;  3ZMQ A;  5BZX A;  1OHC A;  2BGE A;  2HNP A;  5BX1 A;  1LYV A;  2GJT A;  3LJ8 A;  3ZM2 A;  1PA9 A;  3I36 A;  2H4K A;  5EHP A;  4I8N A;  4RH5 A;  2I3R A;  1LQF A;  1P15 A;  3QCH A;  4GRZ A;  1EEO A;  1OEV A;  4KYQ A;  1L8K A;  5BZZ A;  4BPC A;  2HY3 A;  2I3U A;  2DXP A;  1AAX A;  1T4J A;  4RHG A;  4WTY A;  2MBC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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