1GFYA

Residue 259 is a key determinant of substrate specificity of protein-tyrosine phosphatase 1b and alpha
Total Genus 111
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
296
structure length
296
Chain Sequence
MEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYVNVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKTYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLDMRKFRCQLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Residue 259 is a key determinant of substrate specificity of protein-tyrosine phosphatases 1B and alpha.
pubmed doi rcsb
molecule keywords PROTEIN (PROTEIN-TYROSINE PHOSPHATASE 1B)
molecule tags Hydrolase
source organism Homo sapiens
total genus 111
structure length 296
sequence length 296
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1gfyA00
3I80A 3F9BA 3S3FA 4D3PA 2B4PA 1OEOX 2QCJA 4H1OA 5LXQB 1BZCA 1EENA 3QCCA 2G6ZA 4GFVA 4KI9A 2CNFA 1Q6JA 4OHDA 1LARA 4MBBA 5BX1A 3ZMPA 5KA9A 3QCIA 4GRZA 4RKKA 1NL9A 2FH7A 4QUMA 5BZXA 1G1FA 3V0FA 3BRHA 1XBOA 3S3EA 2QCTA 1Q1MA 4Y2EA 2J16B 2PI7A 1OEUA 3D44A 1XRIA 4NYHA 4RH9A 5K25A 1ZZWA 1NWLA 2VEYA 1YZ4A 1XXVA 3CWEA 3QKPA 4B04A 2QDMA 3RGOA 3D42A 2CNIA 1NNYA 2Q05A 2I3UA 2RF6A 3BLTA 2G59A 1G4WR 4BJOA 4GE5A 3AWGA 2CNHA 3H2XA 4QAHA 3QCKA 1OHCA 1SUGA 2DXPA 2NTAA 2OC3A 3V0IA 4GE6A 4YR8B 4NNDA 1LQFA 2H4KA 1BZJA 2NT7A 1YWFA 3S3KA 5J8RA 2H03A 4QBEA 1ZC0A 2OZ5A 1OEVA 2CM2A 3V0JA 1YTNA 3AWEA 1BZHA 4WU3A 2I6JA 5EHPA 3ZM0A 3O4TA 2I4HA 4BPCA 1PA9A 3O5XA 4ZRTA 2VEUA 2H4VA 1L8KA 2BIJA 1Q6NA 1D5RA 2I42A 3QCHA 4DGPA 1L8GA 4ZN5A 3QCBA 2Q47A 2OOQA 2HNQA 4PVGA 1T4JA 4GE2A 2I5XA 1PTTA 5BUGA 4TVVA 2NLKA 2I6IA 1M3GA 4GWFA 2NZ6A 4HRFA 1C83A 1OHEA 3I36A 1C84A 2QDCA 4OHIA 1WAXA 1Q6PA 5K9WA 3GXHA 3QCEA 5KABA 1JLNA 2GWOA 3S4OA 3F41A 1ONYA 2I3RA 2QBSA 3D1OA 1C88A 1YPTA 1JF7A 4S0GA 1NO6A 1Q6SA 4IKCA 2PBNA 2F71A 3I7ZA 4RI4A 2CNGA 2I4GA 1I9TA 5GTJA 1PXHA 2QDPA 1R6HA 3O3LA 2WGPA 1LYVA 1GFYA 2HNPA 4HJPA 2BZLA 2I6PA 2PT0A 3SR9A 1I57A 1KAVA 2YDUA 1FPRA 1NZ7A 1T49A 2R0BA 3MOZA 5KA2A 1ZCLA 2B49A 5KA4A 1A5YA 2F6WA 2AZRA 3MMJA 5AWXA 2AHSA 2QBRA 4DGXA 1PTVA 1U26A 2MBCA 2CM3A 4R0TA 4JMKA 1G7FA 4NX8A 2I75A 2PA5A 2H04A 1G4US 4GFUA 3QCGA 1QZ0A 4D3QA 4NWFA 1U24A 3ZV2A 1OEMX 3O4UA 2HXPA 4J51A 3D1QA 4WU2A 2SHPA 2QBQA 3EU0A 3F81A 3M4UA 3F9AA 4H34A 1OETA 5HDEA 1RPMA 3B7OA 4Z6BA 3V0GA 2QEPA 2VEVA 3O4SA 2ZN7A 2H02A 2I4EA 2B4SA 4OHLA 4GRYA 1ECVA 5MMZB 3D1HA 3SMEA 1C86A 2HC2A 2C7SA 2GP0A 3D9CA 1I9SA 1EEOA 2CM8A 3GXGA 5I6VA 1G7GA 4HJQA 1OHDA 2JJDA 2QBPA 1P15A 2HC1A 2Y2FA 2FJNA 3ZM3A 2IMGA 2NV5A 3A5KA 2ESBA 2BGEA 3S4EA 5K23A 1FQ1A 1XM2A 3BM8A 1ZCKA 3MOWA 4RDDA 2BV5A 2M3VA 2VEWA 3EMUA 5K24A 4R30A 4KYRA 1FPZA 4I8NA 1OESA 3QCMA 4R0SA 3RGQA 3QCLA 2CNEA 4JBCA 2H4GA 3V0HA 1KAKA 5IBMA 2B07A 4ZI4A 5KA8A 2A8BA 3RZ2A 2GJTA 3NMEA 5KA3A 2F70A 2I6OA 5K9VA 1C87A 2CMAA 3V0EA 2J16A 3F99A 1G1HA 2F46A 1C85A 4RH5A 1YTWA 2CFVA 3EZZA 2HCMA 4ICZA 1Q6MA 2I1YA 3QCFA 1U25A 3S3HA 2HB1A 4OHEA 1ONZA 2PQ5A 3PS5A 3CM3A 2F6VA 3ZMQA 1YTSA 4WTYA 2F6YA 5KA7A 5KADA 2P6XA 3QCJA 1YN9A 2HY3A 5KACA 2CJZA 4RI5A 3EB1A 1RXDA 3QKQA 5EHRA 5K22A 2A3KA 1J4XA 2BGDA 3OMHA 3A5JA 2I6MA 2B3OA 1YGRA 5KA1A 3ZM2A 2F6FA 2NT2A 2J17A 4GS0A 3U96A 1X24A 2ZMMA 2E0TA 1YGUA 2OUDA 4D3RA 3QCNA 2F6TA 1NWEA 4JMJA 4Y14A 3EAXA 1PA1A 1XXPA 4JNBA 2CMBA 2B4UA 2P4DA 4WOHA 3ZM1A 3V0DA 2VEXA 1Q6TA 1PTYA 2FJMA 3QCDA 4YAAA 4QUNA 5BZZA 1YFOA 1PH0A 5KA0A 3BLUA 4OHHA 3LJ8A 4AZ1A 2HVLA 1QXKA 3RO1A 2Y96A 2CM7A 5IBSA 4RHGA 2F6ZA 4QAPA 2C46A 1GWZA 5KAAA 1T48A 4ERCA 1PTUA 3AWFA 1AAXA 3OLRA 1WCHA 1WRMA 5M43A 1PYNA 1MKPA 4QBWA 2PSZA 1VHRA 1G1GA 1V3AA 3N0AA 4KYQA 2B4OA 4PYHA 4NWGA 2CMCA
chains in the Genus database with same CATH superfamily
3I80A 3F9BA 3S3FA 4D3PA 2B4PA 4CVLA 1OEOX 2QCJA 4H1OA 5LXQB 1BZCA 1EENA 3QCCA 1O5ZA 2G6ZA 4GFVA 4KI9A 2CNFA 1Q6JA 2XPCA 4OHDA 1LARA 4MBBA 5BX1A 3ZMPA 5KA9A 3QCIA 4GRZA 4RKKA 1NL9A 2FH7A 4QUMA 5BZXA 1G1FA 4BUBA 3V0FA 3BRHA 1XBOA 3PYZA 3S3EA 4HV4A 2QCTA 2GCAA 1Q1MA 4Y2EA 2J16B 2PI7A 1OEUA 3D44A 1XRIA 4NYHA 1J6UA 4RH9A 5K25A 1ZZWA 1NWLA 2VEYA 1YZ4A 1XXVA 3QCZA 3CWEA 3QKPA 4B04A 2QDMA 3RGOA 3D42A 2UUOA 2CNIA 1NNYA 2GC5A 2Q05A 1GQQA 2I3UA 4C13A 2RF6A 3BLTA 2G59A 1G4WR 4BJOA 4GE5A 3AWGA 2CNHA 3H2XA 4QAHA 3QCKA 1OHCA 1SUGA 2DXPA 2NTAA 2OC3A 3V0IA 4GE6A 4YR8B 4NNDA 1LQFA 2H4KA 1BZJA 2NT7A 1YWFA 3S3KA 5J8RA 2H03A 4QBEA 1ZC0A 2OZ5A 1OEVA 2CM2A 3UAGA 3V0JA 1YTNA 3AWEA 1P31A 3N2AA 2Y66A 4UAGA 1BZHA 4WU3A 2I6JA 5EHPA 3ZM0A 3O4TA 2I4HA 4BPCA 1PA9A 3O5XA 2VTDA 4ZRTA 2VEUA 2H4VA 1L8KA 2BIJA 1Q6NA 1D5RA 2I42A 2GCBA 3QCHA 4DGPA 1L8GA 4ZN5A 3QCBA 2Q47A 2OOQA 2HNQA 4PVGA 1T4JA 4GE2A 2I5XA 1PTTA 2JFFA 5BUGA 4TVVA 2NLKA 3LK7A 2I6IA 1M3GA 4GWFA 2NZ6A 4HRFA 1C83A 1OHEA 3I36A 1C84A 2AM2A 2QDCA 4OHIA 1WAXA 1Q6PA 5K9WA 3GXHA 3QCEA 5KABA 1JLNA 2GWOA 4BUCA 3S4OA 3F41A 1ONYA 2I3RA 2QBSA 3D1OA 1C88A 1YPTA 1JF7A 4S0GA 1NO6A 1Q6SA 4CVKA 1FGSA 4IKCA 2XJAA 2PBNA 2F71A 2VTEA 3I7ZA 4RI4A 2CNGA 2I4GA 4C12A 1I9TA 5GTJA 1PXHA 2QDPA 1R6HA 2Y1OA 3O3LA 2WJPA 2WGPA 3MVNA 1LYVA 1GFYA 2HNPA 4HJPA 1UAGA 2BZLA 2I6PA 2PT0A 1P3DA 3SR9A 1I57A 1KAVA 2YDUA 1FPRA 1NZ7A 1T49A 2R0BA 3MOZA 5KA2A 1ZCLA 2B49A 5KA4A 1A5YA 3ZL8A 2F6WA 3ZM5A 2AZRA 2GC6A 3MMJA 5AWXA 2AHSA 2QBRA 4DGXA 1PTVA 1U26A 2MBCA 2CM3A 4R0TA 4JMKA 1G7FA 4NX8A 2I75A 2PA5A 2H04A 1G4US 4GFUA 3QCGA 1QZ0A 4D3QA 4NWFA 1U24A 3ZV2A 1OEMX 3O4UA 2HXPA 4J51A 3D1QA 4WU2A 2SHPA 2QBQA 3EU0A 3F81A 3M4UA 3F9AA 4H34A 1OETA 5HDEA 2UAGA 1RPMA 3B7OA 4Z6BA 2Y68A 3V0GA 2QEPA 2UUPA 2VEVA 1W7KA 3O4SA 2ZN7A 2H02A 4QF5A 2F00A 2I4EA 2B4SA 1E0DA 4OHLA 4GRYA 1ECVA 5MMZB 1JBWA 3D1HA 1C86A 2HC2A 2C7SA 2GP0A 3D9CA 3SMEA 1I9SA 1EEOA 2CM8A 3GXGA 5I6VA 1G7GA 4HJQA 2X5OA 1OHDA 2JJDA 2QBPA 1P15A 2HC1A 2Y2FA 2FJNA 3ZM3A 2IMGA 2NV5A 3A5KA 2ESBA 2BGEA 3S4EA 5K23A 1FQ1A 1XM2A 3BM8A 1ZCKA 3MOWA 4RDDA 2BV5A 2M3VA 2VEWA 3EMUA 5K24A 4R30A 2AM1A 4KYRA 1FPZA 4I8NA 1OESA 2VORA 3QCMA 4R0SA 3HN7A 3RGQA 3QCLA 2CNEA 4JBCA 1GG4A 2H4GA 3V0HA 1KAKA 5IBMA 2B07A 2VOSA 4ZI4A 5KA8A 2A8BA 3RZ2A 2GJTA 3NMEA 4NWGA 5KA3A 2F70A 2I6OA 5K9VA 1C87A 2CMAA 3V0EA 2J16A 3F99A 1G1HA 2F46A 1C85A 4RH5A 1YTWA 2CFVA 3EZZA 2HCMA 4ICZA 1Q6MA 2I1YA 3QCFA 1U25A 3S3HA 2HB1A 4OHEA 1ONZA 2PQ5A 3PS5A 3CM3A 2F6VA 3ZMQA 1YTSA 4WTYA 2F6YA 5KA7A 1W78A 5KADA 2P6XA 3QCJA 5A5FA 1YN9A 2HY3A 5KACA 2CJZA 4RI5A 3EB1A 1RXDA 3QKQA 5EHRA 2JFHA 5K22A 2A3KA 1J4XA 2BGDA 3OMHA 3A5JA 5A5EA 2I6MA 1EEHA 2B3OA 3ZM6A 1YGRA 5KA1A 3ZM2A 2F6FA 2NT2A 2J17A 4GS0A 3U96A 1X24A 2ZMMA 2E0TA 1YGUA 2OUDA 4D3RA 3QCNA 2F6TA 1NWEA 4JMJA 4Y14A 2JFGA 3EAXA 1PA1A 1XXPA 4JNBA 2CMBA 3NRSA 2B4UA 1E8CA 4ZIYA 2P4DA 4WOHA 3ZM1A 3V0DA 2VEXA 1Q6TA 1PTYA 2FJMA 3QCDA 4YAAA 4QUNA 5BZZA 4QDIA 1YFOA 1PH0A 5KA0A 3BLUA 4OHHA 3LJ8A 4AZ1A 2Y67A 2HVLA 1QXKA 3RO1A 2Y96A 2CM7A 5IBSA 4RHGA 2F6ZA 4QAPA 2C46A 1GWZA 5KAAA 1T48A 4CVMA 4ERCA 1PTUA 3AWFA 1AAXA 3OLRA 1JBVA 1WCHA 1WRMA 5M43A 1PYNA 1MKPA 4QBWA 2PSZA 1VHRA 2WTZA 1G1GA 1V3AA 3N0AA 4KYQA 2B4OA 4PYHA 1GQYA 2CMCA
chains in the Genus database with same CATH topology
3I80A 3F9BA 3S3FA 4D3PA 2B4PA 1OEOX 2QCJA 4H1OA 5LXQB 1BZCA 1EENA 3QCCA 2G6ZA 4GFVA 4KI9A 2CNFA 1Q6JA 4OHDA 1LARA 4MBBA 5BX1A 3ZMPA 5KA9A 3QCIA 4GRZA 4RKKA 1NL9A 2FH7A 4QUMA 5BZXA 1G1FA 3V0FA 3BRHA 1XBOA 3S3EA 2QCTA 1Q1MA 4Y2EA 2J16B 2PI7A 1OEUA 3D44A 1XRIA 4NYHA 4RH9A 5K25A 1ZZWA 1NWLA 2VEYA 1YZ4A 1XXVA 3CWEA 3QKPA 4B04A 2QDMA 3RGOA 3D42A 2CNIA 1NNYA 2Q05A 2I3UA 2RF6A 3BLTA 2G59A 1G4WR 4BJOA 4GE5A 3AWGA 2CNHA 3H2XA 4QAHA 3QCKA 1OHCA 1SUGA 2DXPA 2NTAA 2OC3A 3V0IA 4GE6A 4YR8B 4NNDA 1LQFA 2H4KA 1BZJA 2NT7A 1YWFA 3S3KA 5J8RA 2H03A 4QBEA 1ZC0A 2OZ5A 1OEVA 2CM2A 3V0JA 1YTNA 3AWEA 1BZHA 4WU3A 2I6JA 5EHPA 3ZM0A 3O4TA 2I4HA 4BPCA 1PA9A 3O5XA 4ZRTA 2VEUA 2H4VA 1L8KA 2BIJA 1Q6NA 1D5RA 2I42A 3QCHA 4DGPA 1L8GA 4ZN5A 3QCBA 2Q47A 2OOQA 2HNQA 4PVGA 1T4JA 4GE2A 2I5XA 1PTTA 5BUGA 4TVVA 2NLKA 2I6IA 1M3GA 4GWFA 2NZ6A 4HRFA 1C83A 1OHEA 3I36A 1C84A 2QDCA 4OHIA 1WAXA 1Q6PA 5K9WA 3GXHA 3QCEA 5KABA 1JLNA 2GWOA 3S4OA 3F41A 1ONYA 2I3RA 2QBSA 3D1OA 1C88A 1YPTA 1JF7A 4S0GA 1NO6A 1Q6SA 4IKCA 2PBNA 2F71A 3I7ZA 4RI4A 2CNGA 2I4GA 1I9TA 5GTJA 1PXHA 2QDPA 1R6HA 3O3LA 2WGPA 1LYVA 1GFYA 2HNPA 4HJPA 2BZLA 2I6PA 2PT0A 3SR9A 1I57A 1KAVA 2YDUA 1FPRA 1NZ7A 1T49A 2R0BA 3MOZA 5KA2A 1ZCLA 2B49A 5KA4A 1A5YA 2F6WA 2AZRA 3MMJA 5AWXA 2AHSA 2QBRA 4DGXA 1PTVA 1U26A 2MBCA 2CM3A 4R0TA 4JMKA 1G7FA 4NX8A 2I75A 2PA5A 2H04A 1G4US 4GFUA 3QCGA 1QZ0A 4D3QA 4NWFA 1U24A 3ZV2A 1OEMX 3O4UA 2HXPA 4J51A 3D1QA 4WU2A 2SHPA 2QBQA 3EU0A 3F81A 3M4UA 3F9AA 4H34A 1OETA 5HDEA 1RPMA 3B7OA 4Z6BA 3V0GA 2QEPA 2VEVA 3O4SA 2ZN7A 2H02A 2I4EA 2B4SA 4OHLA 4GRYA 1ECVA 5MMZB 3D1HA 3SMEA 1C86A 2HC2A 2C7SA 2GP0A 3D9CA 1I9SA 1EEOA 2CM8A 3GXGA 5I6VA 1G7GA 4HJQA 1OHDA 2JJDA 2QBPA 1P15A 2HC1A 2Y2FA 2FJNA 3ZM3A 2IMGA 2NV5A 3A5KA 2ESBA 2BGEA 3S4EA 5K23A 1FQ1A 1XM2A 3BM8A 1ZCKA 3MOWA 4RDDA 2BV5A 2M3VA 2VEWA 3EMUA 5K24A 4R30A 4KYRA 1FPZA 4I8NA 1OESA 3QCMA 4R0SA 3RGQA 3QCLA 2CNEA 4JBCA 2H4GA 3V0HA 1KAKA 5IBMA 2B07A 4ZI4A 5KA8A 2A8BA 3RZ2A 2GJTA 3NMEA 5KA3A 2F70A 2I6OA 5K9VA 1C87A 2CMAA 3V0EA 2J16A 3F99A 1G1HA 2F46A 1C85A 4RH5A 1YTWA 2CFVA 3EZZA 2HCMA 4ICZA 1Q6MA 2I1YA 3QCFA 1U25A 3S3HA 2HB1A 4OHEA 1ONZA 2PQ5A 3PS5A 3CM3A 2F6VA 3ZMQA 1YTSA 4WTYA 2F6YA 5KA7A 5KADA 2P6XA 3QCJA 1YN9A 2HY3A 5KACA 2CJZA 4RI5A 3EB1A 1RXDA 3QKQA 5EHRA 5K22A 2A3KA 1J4XA 2BGDA 3OMHA 3A5JA 2I6MA 2B3OA 1YGRA 5KA1A 3ZM2A 2F6FA 2NT2A 2J17A 4GS0A 3U96A 1X24A 2ZMMA 2E0TA 1YGUA 2OUDA 4D3RA 3QCNA 2F6TA 1NWEA 4JMJA 4Y14A 3EAXA 1PA1A 1XXPA 4JNBA 2CMBA 2B4UA 2P4DA 4WOHA 3ZM1A 3V0DA 2VEXA 1Q6TA 1PTYA 2FJMA 3QCDA 4YAAA 4QUNA 5BZZA 1YFOA 1PH0A 5KA0A 3BLUA 4OHHA 3LJ8A 4AZ1A 2HVLA 1QXKA 3RO1A 2Y96A 2CM7A 5IBSA 4RHGA 2F6ZA 4QAPA 2C46A 1GWZA 5KAAA 1T48A 4ERCA 1PTUA 3AWFA 1AAXA 3OLRA 1WCHA 1WRMA 5M43A 1PYNA 1MKPA 4QBWA 2PSZA 1VHRA 1G1GA 1V3AA 3N0AA 4KYQA 2B4OA 4PYHA 4NWGA 2CMCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I80 A;  3F9B A;  3S3F A;  4D3P A;  2B4P A;  1OEO X;  2QCJ A;  4H1O A;  5LXQ B;  1BZC A;  1EEN A;  3QCC A;  2G6Z A;  4GFV A;  4KI9 A;  2CNF A;  1Q6J A;  4OHD A;  1LAR A;  4MBB A;  5BX1 A;  3ZMP A;  5KA9 A;  3QCI A;  4GRZ A;  4RKK A;  1NL9 A;  2FH7 A;  4QUM A;  5BZX A;  1G1F A;  3V0F A;  3BRH A;  1XBO A;  3S3E A;  2QCT A;  1Q1M A;  4Y2E A;  2J16 B;  2PI7 A;  1OEU A;  3D44 A;  1XRI A;  4NYH A;  4RH9 A;  5K25 A;  1ZZW A;  1NWL A;  2VEY A;  1YZ4 A;  1XXV A;  3CWE A;  3QKP A;  4B04 A;  2QDM A;  3RGO A;  3D42 A;  2CNI A;  1NNY A;  2Q05 A;  2I3U A;  2RF6 A;  3BLT A;  2G59 A;  1G4W R;  4BJO A;  4GE5 A;  3AWG A;  2CNH A;  3H2X A;  4QAH A;  3QCK A;  1OHC A;  1SUG A;  2DXP A;  2NTA A;  2OC3 A;  3V0I A;  4GE6 A;  4YR8 B;  4NND A;  1LQF A;  2H4K A;  1BZJ A;  2NT7 A;  1YWF A;  3S3K A;  5J8R A;  2H03 A;  4QBE A;  1ZC0 A;  2OZ5 A;  1OEV A;  2CM2 A;  3V0J A;  1YTN A;  3AWE A;  1BZH A;  4WU3 A;  2I6J A;  5EHP A;  3ZM0 A;  3O4T A;  2I4H A;  4BPC A;  1PA9 A;  3O5X A;  4ZRT A;  2VEU A;  2H4V A;  1L8K A;  2BIJ A;  1Q6N A;  1D5R A;  2I42 A;  3QCH A;  4DGP A;  1L8G A;  4ZN5 A;  3QCB A;  2Q47 A;  2OOQ A;  2HNQ A;  4PVG A;  1T4J A;  4GE2 A;  2I5X A;  1PTT A;  5BUG A;  4TVV A;  2NLK A;  2I6I A;  1M3G A;  4GWF A;  2NZ6 A;  4HRF A;  1C83 A;  1OHE A;  3I36 A;  1C84 A;  2QDC A;  4OHI A;  1WAX A;  1Q6P A;  5K9W A;  3GXH A;  3QCE A;  5KAB A;  1JLN A;  2GWO A;  3S4O A;  3F41 A;  1ONY A;  2I3R A;  2QBS A;  3D1O A;  1C88 A;  1YPT A;  1JF7 A;  4S0G A;  1NO6 A;  1Q6S A;  4IKC A;  2PBN A;  2F71 A;  3I7Z A;  4RI4 A;  2CNG A;  2I4G A;  1I9T A;  5GTJ A;  1PXH A;  2QDP A;  1R6H A;  3O3L A;  2WGP A;  1LYV A;  1GFY A;  2HNP A;  4HJP A;  2BZL A;  2I6P A;  2PT0 A;  3SR9 A;  1I57 A;  1KAV A;  2YDU A;  1FPR A;  1NZ7 A;  1T49 A;  2R0B A;  3MOZ A;  5KA2 A;  1ZCL A;  2B49 A;  5KA4 A;  1A5Y A;  2F6W A;  2AZR A;  3MMJ A;  5AWX A;  2AHS A;  2QBR A;  4DGX A;  1PTV A;  1U26 A;  2MBC A;  2CM3 A;  4R0T A;  4JMK A;  1G7F A;  4NX8 A;  2I75 A;  2PA5 A;  2H04 A;  1G4U S;  4GFU A;  3QCG A;  1QZ0 A;  4D3Q A;  4NWF A;  1U24 A;  3ZV2 A;  1OEM X;  3O4U A;  2HXP A;  4J51 A;  3D1Q A;  4WU2 A;  2SHP A;  2QBQ A;  3EU0 A;  3F81 A;  3M4U A;  3F9A A;  4H34 A;  1OET A;  5HDE A;  1RPM A;  3B7O A;  4Z6B A;  3V0G A;  2QEP A;  2VEV A;  3O4S A;  2ZN7 A;  2H02 A;  2I4E A;  2B4S A;  4OHL A;  4GRY A;  1ECV A;  5MMZ B;  3D1H A;  3SME A;  1C86 A;  2HC2 A;  2C7S A;  2GP0 A;  3D9C A;  1I9S A;  1EEO A;  2CM8 A;  3GXG A;  5I6V A;  1G7G A;  4HJQ A;  1OHD A;  2JJD A;  2QBP A;  1P15 A;  2HC1 A;  2Y2F A;  2FJN A;  3ZM3 A;  2IMG A;  2NV5 A;  3A5K A;  2ESB A;  2BGE A;  3S4E A;  5K23 A;  1FQ1 A;  1XM2 A;  3BM8 A;  1ZCK A;  3MOW A;  4RDD A;  2BV5 A;  2M3V A;  2VEW A;  3EMU A;  5K24 A;  4R30 A;  4KYR A;  1FPZ A;  4I8N A;  1OES A;  3QCM A;  4R0S A;  3RGQ A;  3QCL A;  2CNE A;  4JBC A;  2H4G A;  3V0H A;  1KAK A;  5IBM A;  2B07 A;  4ZI4 A;  5KA8 A;  2A8B A;  3RZ2 A;  2GJT A;  3NME A;  5KA3 A;  2F70 A;  2I6O A;  5K9V A;  1C87 A;  2CMA A;  3V0E A;  2J16 A;  3F99 A;  1G1H A;  2F46 A;  1C85 A;  4RH5 A;  1YTW A;  2CFV A;  3EZZ A;  2HCM A;  4ICZ A;  1Q6M A;  2I1Y A;  3QCF A;  1U25 A;  3S3H A;  2HB1 A;  4OHE A;  1ONZ A;  2PQ5 A;  3PS5 A;  3CM3 A;  2F6V A;  3ZMQ A;  1YTS A;  4WTY A;  2F6Y A;  5KA7 A;  5KAD A;  2P6X A;  3QCJ A;  1YN9 A;  2HY3 A;  5KAC A;  2CJZ A;  4RI5 A;  3EB1 A;  1RXD A;  3QKQ A;  5EHR A;  5K22 A;  2A3K A;  1J4X A;  2BGD A;  3OMH A;  3A5J A;  2I6M A;  2B3O A;  1YGR A;  5KA1 A;  3ZM2 A;  2F6F A;  2NT2 A;  2J17 A;  4GS0 A;  3U96 A;  1X24 A;  2ZMM A;  2E0T A;  1YGU A;  2OUD A;  4D3R A;  3QCN A;  2F6T A;  1NWE A;  4JMJ A;  4Y14 A;  3EAX A;  1PA1 A;  1XXP A;  4JNB A;  2CMB A;  2B4U A;  2P4D A;  4WOH A;  3ZM1 A;  3V0D A;  2VEX A;  1Q6T A;  1PTY A;  2FJM A;  3QCD A;  4YAA A;  4QUN A;  5BZZ A;  1YFO A;  1PH0 A;  5KA0 A;  3BLU A;  4OHH A;  3LJ8 A;  4AZ1 A;  2HVL A;  1QXK A;  3RO1 A;  2Y96 A;  2CM7 A;  5IBS A;  4RHG A;  2F6Z A;  4QAP A;  2C46 A;  1GWZ A;  5KAA A;  1T48 A;  4ERC A;  1PTU A;  3AWF A;  1AAX A;  3OLR A;  1WCH A;  1WRM A;  5M43 A;  1PYN A;  1MKP A;  4QBW A;  2PSZ A;  1VHR A;  1G1G A;  1V3A A;  3N0A A;  4KYQ A;  2B4O A;  4PYH A;  4NWG A;  2CMC A; 
#chains in the Genus database with same CATH topology
 3I80 A;  3F9B A;  3S3F A;  4D3P A;  2B4P A;  4CVL A;  1OEO X;  2QCJ A;  4H1O A;  5LXQ B;  1BZC A;  1EEN A;  3QCC A;  1O5Z A;  2G6Z A;  4GFV A;  4KI9 A;  2CNF A;  1Q6J A;  2XPC A;  4OHD A;  1LAR A;  4MBB A;  5BX1 A;  3ZMP A;  5KA9 A;  3QCI A;  4GRZ A;  4RKK A;  1NL9 A;  2FH7 A;  4QUM A;  5BZX A;  1G1F A;  4BUB A;  3V0F A;  3BRH A;  1XBO A;  3PYZ A;  3S3E A;  4HV4 A;  2QCT A;  2GCA A;  1Q1M A;  4Y2E A;  2J16 B;  2PI7 A;  1OEU A;  3D44 A;  1XRI A;  4NYH A;  1J6U A;  4RH9 A;  5K25 A;  1ZZW A;  1NWL A;  2VEY A;  1YZ4 A;  1XXV A;  3QCZ A;  3CWE A;  3QKP A;  4B04 A;  2QDM A;  3RGO A;  3D42 A;  2UUO A;  2CNI A;  1NNY A;  2GC5 A;  2Q05 A;  1GQQ A;  2I3U A;  4C13 A;  2RF6 A;  3BLT A;  2G59 A;  1G4W R;  4BJO A;  4GE5 A;  3AWG A;  2CNH A;  3H2X A;  4QAH A;  3QCK A;  1OHC A;  1SUG A;  2DXP A;  2NTA A;  2OC3 A;  3V0I A;  4GE6 A;  4YR8 B;  4NND A;  1LQF A;  2H4K A;  1BZJ A;  2NT7 A;  1YWF A;  3S3K A;  5J8R A;  2H03 A;  4QBE A;  1ZC0 A;  2OZ5 A;  1OEV A;  2CM2 A;  3UAG A;  3V0J A;  1YTN A;  3AWE A;  1P31 A;  3N2A A;  2Y66 A;  4UAG A;  1BZH A;  4WU3 A;  2I6J A;  5EHP A;  3ZM0 A;  3O4T A;  2I4H A;  4BPC A;  1PA9 A;  3O5X A;  2VTD A;  4ZRT A;  2VEU A;  2H4V A;  1L8K A;  2BIJ A;  1Q6N A;  1D5R A;  2I42 A;  2GCB A;  3QCH A;  4DGP A;  1L8G A;  4ZN5 A;  3QCB A;  2Q47 A;  2OOQ A;  2HNQ A;  4PVG A;  1T4J A;  4GE2 A;  2I5X A;  1PTT A;  2JFF A;  5BUG A;  4TVV A;  2NLK A;  3LK7 A;  2I6I A;  1M3G A;  4GWF A;  2NZ6 A;  4HRF A;  1C83 A;  1OHE A;  3I36 A;  1C84 A;  2AM2 A;  2QDC A;  4OHI A;  1WAX A;  1Q6P A;  5K9W A;  3GXH A;  3QCE A;  5KAB A;  1JLN A;  2GWO A;  4BUC A;  3S4O A;  3F41 A;  1ONY A;  2I3R A;  2QBS A;  3D1O A;  1C88 A;  1YPT A;  1JF7 A;  4S0G A;  1NO6 A;  1Q6S A;  4CVK A;  1FGS A;  4IKC A;  2XJA A;  2PBN A;  2F71 A;  2VTE A;  3I7Z A;  4RI4 A;  2CNG A;  2I4G A;  4C12 A;  1I9T A;  5GTJ A;  1PXH A;  2QDP A;  1R6H A;  2Y1O A;  3O3L A;  2WJP A;  2WGP A;  3MVN A;  1LYV A;  1GFY A;  2HNP A;  4HJP A;  1UAG A;  2BZL A;  2I6P A;  2PT0 A;  1P3D A;  3SR9 A;  1I57 A;  1KAV A;  2YDU A;  1FPR A;  1NZ7 A;  1T49 A;  2R0B A;  3MOZ A;  5KA2 A;  1ZCL A;  2B49 A;  5KA4 A;  1A5Y A;  3ZL8 A;  2F6W A;  3ZM5 A;  2AZR A;  2GC6 A;  3MMJ A;  5AWX A;  2AHS A;  2QBR A;  4DGX A;  1PTV A;  1U26 A;  2MBC A;  2CM3 A;  4R0T A;  4JMK A;  1G7F A;  4NX8 A;  2I75 A;  2PA5 A;  2H04 A;  1G4U S;  4GFU A;  3QCG A;  1QZ0 A;  4D3Q A;  4NWF A;  1U24 A;  3ZV2 A;  1OEM X;  3O4U A;  2HXP A;  4J51 A;  3D1Q A;  4WU2 A;  2SHP A;  2QBQ A;  3EU0 A;  3F81 A;  3M4U A;  3F9A A;  4H34 A;  1OET A;  5HDE A;  2UAG A;  1RPM A;  3B7O A;  4Z6B A;  2Y68 A;  3V0G A;  2QEP A;  2UUP A;  2VEV A;  1W7K A;  3O4S A;  2ZN7 A;  2H02 A;  4QF5 A;  2F00 A;  2I4E A;  2B4S A;  1E0D A;  4OHL A;  4GRY A;  1ECV A;  5MMZ B;  1JBW A;  3D1H A;  1C86 A;  2HC2 A;  2C7S A;  2GP0 A;  3D9C A;  3SME A;  1I9S A;  1EEO A;  2CM8 A;  3GXG A;  5I6V A;  1G7G A;  4HJQ A;  2X5O A;  1OHD A;  2JJD A;  2QBP A;  1P15 A;  2HC1 A;  2Y2F A;  2FJN A;  3ZM3 A;  2IMG A;  2NV5 A;  3A5K A;  2ESB A;  2BGE A;  3S4E A;  5K23 A;  1FQ1 A;  1XM2 A;  3BM8 A;  1ZCK A;  3MOW A;  4RDD A;  2BV5 A;  2M3V A;  2VEW A;  3EMU A;  5K24 A;  4R30 A;  2AM1 A;  4KYR A;  1FPZ A;  4I8N A;  1OES A;  2VOR A;  3QCM A;  4R0S A;  3HN7 A;  3RGQ A;  3QCL A;  2CNE A;  4JBC A;  1GG4 A;  2H4G A;  3V0H A;  1KAK A;  5IBM A;  2B07 A;  2VOS A;  4ZI4 A;  5KA8 A;  2A8B A;  3RZ2 A;  2GJT A;  3NME A;  4NWG A;  5KA3 A;  2F70 A;  2I6O A;  5K9V A;  1C87 A;  2CMA A;  3V0E A;  2J16 A;  3F99 A;  1G1H A;  2F46 A;  1C85 A;  4RH5 A;  1YTW A;  2CFV A;  3EZZ A;  2HCM A;  4ICZ A;  1Q6M A;  2I1Y A;  3QCF A;  1U25 A;  3S3H A;  2HB1 A;  4OHE A;  1ONZ A;  2PQ5 A;  3PS5 A;  3CM3 A;  2F6V A;  3ZMQ A;  1YTS A;  4WTY A;  2F6Y A;  5KA7 A;  1W78 A;  5KAD A;  2P6X A;  3QCJ A;  5A5F A;  1YN9 A;  2HY3 A;  5KAC A;  2CJZ A;  4RI5 A;  3EB1 A;  1RXD A;  3QKQ A;  5EHR A;  2JFH A;  5K22 A;  2A3K A;  1J4X A;  2BGD A;  3OMH A;  3A5J A;  5A5E A;  2I6M A;  1EEH A;  2B3O A;  3ZM6 A;  1YGR A;  5KA1 A;  3ZM2 A;  2F6F A;  2NT2 A;  2J17 A;  4GS0 A;  3U96 A;  1X24 A;  2ZMM A;  2E0T A;  1YGU A;  2OUD A;  4D3R A;  3QCN A;  2F6T A;  1NWE A;  4JMJ A;  4Y14 A;  2JFG A;  3EAX A;  1PA1 A;  1XXP A;  4JNB A;  2CMB A;  3NRS A;  2B4U A;  1E8C A;  4ZIY A;  2P4D A;  4WOH A;  3ZM1 A;  3V0D A;  2VEX A;  1Q6T A;  1PTY A;  2FJM A;  3QCD A;  4YAA A;  4QUN A;  5BZZ A;  4QDI A;  1YFO A;  1PH0 A;  5KA0 A;  3BLU A;  4OHH A;  3LJ8 A;  4AZ1 A;  2Y67 A;  2HVL A;  1QXK A;  3RO1 A;  2Y96 A;  2CM7 A;  5IBS A;  4RHG A;  2F6Z A;  4QAP A;  2C46 A;  1GWZ A;  5KAA A;  1T48 A;  4CVM A;  4ERC A;  1PTU A;  3AWF A;  1AAX A;  3OLR A;  1JBV A;  1WCH A;  1WRM A;  5M43 A;  1PYN A;  1MKP A;  4QBW A;  2PSZ A;  1VHR A;  2WTZ A;  1G1G A;  1V3A A;  3N0A A;  4KYQ A;  2B4O A;  4PYH A;  1GQY A;  2CMC A; 
#chains in the Genus database with same CATH homology
 3I80 A;  3F9B A;  3S3F A;  4D3P A;  2B4P A;  1OEO X;  2QCJ A;  4H1O A;  5LXQ B;  1BZC A;  1EEN A;  3QCC A;  2G6Z A;  4GFV A;  4KI9 A;  2CNF A;  1Q6J A;  4OHD A;  1LAR A;  4MBB A;  5BX1 A;  3ZMP A;  5KA9 A;  3QCI A;  4GRZ A;  4RKK A;  1NL9 A;  2FH7 A;  4QUM A;  5BZX A;  1G1F A;  3V0F A;  3BRH A;  1XBO A;  3S3E A;  2QCT A;  1Q1M A;  4Y2E A;  2J16 B;  2PI7 A;  1OEU A;  3D44 A;  1XRI A;  4NYH A;  4RH9 A;  5K25 A;  1ZZW A;  1NWL A;  2VEY A;  1YZ4 A;  1XXV A;  3CWE A;  3QKP A;  4B04 A;  2QDM A;  3RGO A;  3D42 A;  2CNI A;  1NNY A;  2Q05 A;  2I3U A;  2RF6 A;  3BLT A;  2G59 A;  1G4W R;  4BJO A;  4GE5 A;  3AWG A;  2CNH A;  3H2X A;  4QAH A;  3QCK A;  1OHC A;  1SUG A;  2DXP A;  2NTA A;  2OC3 A;  3V0I A;  4GE6 A;  4YR8 B;  4NND A;  1LQF A;  2H4K A;  1BZJ A;  2NT7 A;  1YWF A;  3S3K A;  5J8R A;  2H03 A;  4QBE A;  1ZC0 A;  2OZ5 A;  1OEV A;  2CM2 A;  3V0J A;  1YTN A;  3AWE A;  1BZH A;  4WU3 A;  2I6J A;  5EHP A;  3ZM0 A;  3O4T A;  2I4H A;  4BPC A;  1PA9 A;  3O5X A;  4ZRT A;  2VEU A;  2H4V A;  1L8K A;  2BIJ A;  1Q6N A;  1D5R A;  2I42 A;  3QCH A;  4DGP A;  1L8G A;  4ZN5 A;  3QCB A;  2Q47 A;  2OOQ A;  2HNQ A;  4PVG A;  1T4J A;  4GE2 A;  2I5X A;  1PTT A;  5BUG A;  4TVV A;  2NLK A;  2I6I A;  1M3G A;  4GWF A;  2NZ6 A;  4HRF A;  1C83 A;  1OHE A;  3I36 A;  1C84 A;  2QDC A;  4OHI A;  1WAX A;  1Q6P A;  5K9W A;  3GXH A;  3QCE A;  5KAB A;  1JLN A;  2GWO A;  3S4O A;  3F41 A;  1ONY A;  2I3R A;  2QBS A;  3D1O A;  1C88 A;  1YPT A;  1JF7 A;  4S0G A;  1NO6 A;  1Q6S A;  4IKC A;  2PBN A;  2F71 A;  3I7Z A;  4RI4 A;  2CNG A;  2I4G A;  1I9T A;  5GTJ A;  1PXH A;  2QDP A;  1R6H A;  3O3L A;  2WGP A;  1LYV A;  1GFY A;  2HNP A;  4HJP A;  2BZL A;  2I6P A;  2PT0 A;  3SR9 A;  1I57 A;  1KAV A;  2YDU A;  1FPR A;  1NZ7 A;  1T49 A;  2R0B A;  3MOZ A;  5KA2 A;  1ZCL A;  2B49 A;  5KA4 A;  1A5Y A;  2F6W A;  2AZR A;  3MMJ A;  5AWX A;  2AHS A;  2QBR A;  4DGX A;  1PTV A;  1U26 A;  2MBC A;  2CM3 A;  4R0T A;  4JMK A;  1G7F A;  4NX8 A;  2I75 A;  2PA5 A;  2H04 A;  1G4U S;  4GFU A;  3QCG A;  1QZ0 A;  4D3Q A;  4NWF A;  1U24 A;  3ZV2 A;  1OEM X;  3O4U A;  2HXP A;  4J51 A;  3D1Q A;  4WU2 A;  2SHP A;  2QBQ A;  3EU0 A;  3F81 A;  3M4U A;  3F9A A;  4H34 A;  1OET A;  5HDE A;  1RPM A;  3B7O A;  4Z6B A;  3V0G A;  2QEP A;  2VEV A;  3O4S A;  2ZN7 A;  2H02 A;  2I4E A;  2B4S A;  4OHL A;  4GRY A;  1ECV A;  5MMZ B;  3D1H A;  3SME A;  1C86 A;  2HC2 A;  2C7S A;  2GP0 A;  3D9C A;  1I9S A;  1EEO A;  2CM8 A;  3GXG A;  5I6V A;  1G7G A;  4HJQ A;  1OHD A;  2JJD A;  2QBP A;  1P15 A;  2HC1 A;  2Y2F A;  2FJN A;  3ZM3 A;  2IMG A;  2NV5 A;  3A5K A;  2ESB A;  2BGE A;  3S4E A;  5K23 A;  1FQ1 A;  1XM2 A;  3BM8 A;  1ZCK A;  3MOW A;  4RDD A;  2BV5 A;  2M3V A;  2VEW A;  3EMU A;  5K24 A;  4R30 A;  4KYR A;  1FPZ A;  4I8N A;  1OES A;  3QCM A;  4R0S A;  3RGQ A;  3QCL A;  2CNE A;  4JBC A;  2H4G A;  3V0H A;  1KAK A;  5IBM A;  2B07 A;  4ZI4 A;  5KA8 A;  2A8B A;  3RZ2 A;  2GJT A;  3NME A;  5KA3 A;  2F70 A;  2I6O A;  5K9V A;  1C87 A;  2CMA A;  3V0E A;  2J16 A;  3F99 A;  1G1H A;  2F46 A;  1C85 A;  4RH5 A;  1YTW A;  2CFV A;  3EZZ A;  2HCM A;  4ICZ A;  1Q6M A;  2I1Y A;  3QCF A;  1U25 A;  3S3H A;  2HB1 A;  4OHE A;  1ONZ A;  2PQ5 A;  3PS5 A;  3CM3 A;  2F6V A;  3ZMQ A;  1YTS A;  4WTY A;  2F6Y A;  5KA7 A;  5KAD A;  2P6X A;  3QCJ A;  1YN9 A;  2HY3 A;  5KAC A;  2CJZ A;  4RI5 A;  3EB1 A;  1RXD A;  3QKQ A;  5EHR A;  5K22 A;  2A3K A;  1J4X A;  2BGD A;  3OMH A;  3A5J A;  2I6M A;  2B3O A;  1YGR A;  5KA1 A;  3ZM2 A;  2F6F A;  2NT2 A;  2J17 A;  4GS0 A;  3U96 A;  1X24 A;  2ZMM A;  2E0T A;  1YGU A;  2OUD A;  4D3R A;  3QCN A;  2F6T A;  1NWE A;  4JMJ A;  4Y14 A;  3EAX A;  1PA1 A;  1XXP A;  4JNB A;  2CMB A;  2B4U A;  2P4D A;  4WOH A;  3ZM1 A;  3V0D A;  2VEX A;  1Q6T A;  1PTY A;  2FJM A;  3QCD A;  4YAA A;  4QUN A;  5BZZ A;  1YFO A;  1PH0 A;  5KA0 A;  3BLU A;  4OHH A;  3LJ8 A;  4AZ1 A;  2HVL A;  1QXK A;  3RO1 A;  2Y96 A;  2CM7 A;  5IBS A;  4RHG A;  2F6Z A;  4QAP A;  2C46 A;  1GWZ A;  5KAA A;  1T48 A;  4ERC A;  1PTU A;  3AWF A;  1AAX A;  3OLR A;  1WCH A;  1WRM A;  5M43 A;  1PYN A;  1MKP A;  4QBW A;  2PSZ A;  1VHR A;  1G1G A;  1V3A A;  3N0A A;  4KYQ A;  2B4O A;  4PYH A;  4NWG A;  2CMC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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