1GIRA

Crystal structure of the enzymatic componet of iota-toxin from clostridium perfringens with nadph
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
411
structure length
411
Chain Sequence
IERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure and Site-directed Mutagenesis of Enzymatic Components from Clostridium perfringens Iota-toxin
pubmed doi rcsb
molecule tags Toxin
molecule keywords IOTA TOXIN COMPONENT IA
total genus 132
structure length 411
sequence length 411
ec nomenclature
pdb deposition date 2001-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 1girA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 1girA01
4FMLA 1PWPA 1GIRA 1GZFA 2C8CA 1OJZA 2GWMA 4DV8A 5GTTA 2C8FE 2C8EE 4PKUA 1GY0A 1GZEA 2GWLA 2J3XA 2J3VA 1YQYA 4WF6A 3NTSA 4PKSA 1ZXVA 5DZQA 4PKVA 2WN5A 1R45A 4PKQA 3BW8A 4TR5A 3U0JA 5BWMB 2C8DA 1JKYA 1GXZA 1R4BA 2BOVB 4XM6A 4H0TA 1PWWA 1PWUA 2C89A 4FK7A 4PKTA 4FXQA 4H0XA 2C8HA 1GXYA 2C8GA 1OG3A 2C8AA 1G24A 4GY2A 4H03A 5H04A 1UZIA 1PWQA 2WN7A 2A78B 4XSGB 5D1TA 2WN6A 4XSHB 1QS1A 4GF1A 4H0YA 2J3ZA 1J7NA 1OG1A 2A9KB 1OJQA 1OG4A 2WN4A 1PWVA 5H03A 4H0VA 2WN8A 4PKRA 5D1SA 1GIQA 4XM8A 1QS2A 4PKWA 5D1UA 2C8BX 4XM7A 4ELNA 3BUZA
chains in the Genus database with same CATH superfamily
4FMLA 1PWPA 1GIRA 1GZFA 2C8CA 1OJZA 2GWMA 4DV8A 5GTTA 2C8FE 2C8EE 4PKUA 1GY0A 1GZEA 2GWLA 2J3XA 2J3VA 1YQYA 4WF6A 3NTSA 4PKSA 1ZXVA 5DZQA 4PKVA 2WN5A 1R45A 4PKQA 3BW8A 4TR5A 3U0JA 5BWMB 2C8DA 1JKYA 1GXZA 1R4BA 2BOVB 4XM6A 4H0TA 1PWWA 1PWUA 2C89A 4FK7A 4PKTA 4FXQA 4H0XA 2C8HA 1GXYA 2C8GA 1OG3A 2C8AA 1G24A 4GY2A 4H03A 5H04A 1UZIA 1PWQA 2WN7A 2A78B 4XSGB 5D1TA 2WN6A 4XSHB 1QS1A 4GF1A 4H0YA 2J3ZA 1J7NA 1OG1A 2A9KB 1OJQA 1OG4A 2WN4A 1PWVA 5H03A 4H0VA 2WN8A 4PKRA 5D1SA 1GIQA 4XM8A 1QS2A 4PKWA 5D1UA 2C8BX 4XM7A 4ELNA 3BUZA
chains in the Genus database with same CATH topology
4FMLA 1PWPA 1GIRA 1GZFA 2C8CA 1OJZA 2GWMA 4DV8A 5GTTA 2C8FE 2C8EE 4PKUA 1GY0A 1GZEA 2GWLA 2J3XA 2J3VA 1YQYA 4WF6A 3NTSA 4PKSA 1ZXVA 5DZQA 4PKVA 2WN5A 1R45A 4PKQA 3BW8A 4TR5A 3U0JA 5BWMB 2C8DA 1JKYA 1GXZA 1R4BA 2BOVB 4XM6A 4H0TA 1PWWA 1PWUA 2C89A 4FK7A 4PKTA 4FXQA 4H0XA 2C8HA 1GXYA 2C8GA 1OG3A 2C8AA 1G24A 4GY2A 4H03A 5H04A 1UZIA 1PWQA 2WN7A 2A78B 4XSGB 5D1TA 2WN6A 4XSHB 1QS1A 4GF1A 4H0YA 2J3ZA 1J7NA 1OG1A 2A9KB 1OJQA 1OG4A 2WN4A 1PWVA 5H03A 4H0VA 2WN8A 4PKRA 5D1SA 1GIQA 4XM8A 1QS2A 4PKWA 5D1UA 2C8BX 4XM7A 4ELNA 3BUZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FML A;  1PWP A;  1GIR A;  1GZF A;  2C8C A;  1OJZ A;  2GWM A;  4DV8 A;  5GTT A;  2C8F E;  2C8E E;  4PKU A;  1GY0 A;  1GZE A;  2GWL A;  2J3X A;  2J3V A;  1YQY A;  4WF6 A;  3NTS A;  4PKS A;  1ZXV A;  5DZQ A;  4PKV A;  2WN5 A;  1R45 A;  4PKQ A;  3BW8 A;  4TR5 A;  3U0J A;  5BWM B;  2C8D A;  1JKY A;  1GXZ A;  1R4B A;  2BOV B;  4XM6 A;  4H0T A;  1PWW A;  1PWU A;  2C89 A;  4FK7 A;  4PKT A;  4FXQ A;  4H0X A;  2C8H A;  1GXY A;  2C8G A;  1OG3 A;  2C8A A;  1G24 A;  4GY2 A;  4H03 A;  5H04 A;  1UZI A;  1PWQ A;  2WN7 A;  2A78 B;  4XSG B;  5D1T A;  2WN6 A;  4XSH B;  1QS1 A;  4GF1 A;  4H0Y A;  2J3Z A;  1J7N A;  1OG1 A;  2A9K B;  1OJQ A;  1OG4 A;  2WN4 A;  1PWV A;  5H03 A;  4H0V A;  2WN8 A;  4PKR A;  5D1S A;  1GIQ A;  4XM8 A;  1QS2 A;  4PKW A;  5D1U A;  2C8B X;  4XM7 A;  4ELN A;  3BUZ A; 
#chains in the Genus database with same CATH topology
 4FML A;  1PWP A;  1GIR A;  1GZF A;  2C8C A;  1OJZ A;  2GWM A;  4DV8 A;  5GTT A;  2C8F E;  2C8E E;  4PKU A;  1GY0 A;  1GZE A;  2GWL A;  2J3X A;  2J3V A;  1YQY A;  4WF6 A;  3NTS A;  4PKS A;  1ZXV A;  5DZQ A;  4PKV A;  2WN5 A;  1R45 A;  4PKQ A;  3BW8 A;  4TR5 A;  3U0J A;  5BWM B;  2C8D A;  1JKY A;  1GXZ A;  1R4B A;  2BOV B;  4XM6 A;  4H0T A;  1PWW A;  1PWU A;  2C89 A;  4FK7 A;  4PKT A;  4FXQ A;  4H0X A;  2C8H A;  1GXY A;  2C8G A;  1OG3 A;  2C8A A;  1G24 A;  4GY2 A;  4H03 A;  5H04 A;  1UZI A;  1PWQ A;  2WN7 A;  2A78 B;  4XSG B;  5D1T A;  2WN6 A;  4XSH B;  1QS1 A;  4GF1 A;  4H0Y A;  2J3Z A;  1J7N A;  1OG1 A;  2A9K B;  1OJQ A;  1OG4 A;  2WN4 A;  1PWV A;  5H03 A;  4H0V A;  2WN8 A;  4PKR A;  5D1S A;  1GIQ A;  4XM8 A;  1QS2 A;  4PKW A;  5D1U A;  2C8B X;  4XM7 A;  4ELN A;  3BUZ A; 
#chains in the Genus database with same CATH homology
 4FML A;  1PWP A;  1GIR A;  1GZF A;  2C8C A;  1OJZ A;  2GWM A;  4DV8 A;  5GTT A;  2C8F E;  2C8E E;  4PKU A;  1GY0 A;  1GZE A;  2GWL A;  2J3X A;  2J3V A;  1YQY A;  4WF6 A;  3NTS A;  4PKS A;  1ZXV A;  5DZQ A;  4PKV A;  2WN5 A;  1R45 A;  4PKQ A;  3BW8 A;  4TR5 A;  3U0J A;  5BWM B;  2C8D A;  1JKY A;  1GXZ A;  1R4B A;  2BOV B;  4XM6 A;  4H0T A;  1PWW A;  1PWU A;  2C89 A;  4FK7 A;  4PKT A;  4FXQ A;  4H0X A;  2C8H A;  1GXY A;  2C8G A;  1OG3 A;  2C8A A;  1G24 A;  4GY2 A;  4H03 A;  5H04 A;  1UZI A;  1PWQ A;  2WN7 A;  2A78 B;  4XSG B;  5D1T A;  2WN6 A;  4XSH B;  1QS1 A;  4GF1 A;  4H0Y A;  2J3Z A;  1J7N A;  1OG1 A;  2A9K B;  1OJQ A;  1OG4 A;  2WN4 A;  1PWV A;  5H03 A;  4H0V A;  2WN8 A;  4PKR A;  5D1S A;  1GIQ A;  4XM8 A;  1QS2 A;  4PKW A;  5D1U A;  2C8B X;  4XM7 A;  4ELN A;  3BUZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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