1GJJA

N-terminal constant region of the nuclear envelope protein lap2
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
Knots found
sequence length
153
structure length
93
Chain Sequence
MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRDVTELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the constant region of nuclear envelope protein LAP2 reveals two LEM-domain structures: one binds BAF and the other binds DNA.
pubmed doi rcsb
molecule tags Membrane protein
source organism Homo sapiens
molecule keywords LAP2
total genus 42
structure length 93
sequence length 153
other databases KnotProt 2.0: Artifct S 7.4 51 +3.
ec nomenclature
pdb deposition date 2001-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03020 LEM LEM domain
A PF08198 Thymopoietin Thymopoietin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.40 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 1gjjA00
1JEIA 1H9FA 2ODCI 2ODGC 1H9EA 1GJJA
chains in the Genus database with same CATH superfamily
3LLRA 3QKJA 1GKUB 2KFVA 1Y02A 2G80A 2KVDA 2RNNA 1V66A 2KVUA 1GL9B 1YNSA 2RNOA 2KVEA 2LC3A 2QNFA 2A8VA 1JEQA 1EN7A 1H1JS 1H9FA 1JJRA 1E7DA 2QNCA 1KHCA 2WQGA 4BITA 2ODCI 1A62A 3L0OA 2KW9A 2LD7A 1GJJA 2DK4A 1ZBHA 1A63A 2W51A 2JVWA 2ODGC 3FLGA 4UZWA 1JEIA 1ZS9A 2MPHA 1A8VA 1E7LA 5CIUA 2HJQA 1H9EA
chains in the Genus database with same CATH topology
1GKUB 2KFVA 1Y02A 2G80A 1GL9B 1YNSA 2LC3A 2QNFA 2A8VA 1H9FA 1EN7A 1E7DA 2QNCA 2ODCI 1A62A 3L0OA 2LD7A 1GJJA 2DK4A 1A63A 2W51A 2ODGC 1JEIA 1ZS9A 2MPHA 1A8VA 1E7LA 2HJQA 1H9EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JEI A;  1H9F A;  2ODC I;  2ODG C;  1H9E A;  1GJJ A; 
#chains in the Genus database with same CATH topology
 3LLR A;  3QKJ A;  1GKU B;  2KFV A;  1Y02 A;  2G80 A;  2KVD A;  2RNN A;  1V66 A;  2KVU A;  1GL9 B;  1YNS A;  2RNO A;  2KVE A;  2LC3 A;  2QNF A;  2A8V A;  1JEQ A;  1EN7 A;  1H1J S;  1H9F A;  1JJR A;  1E7D A;  2QNC A;  1KHC A;  2WQG A;  4BIT A;  2ODC I;  1A62 A;  3L0O A;  2KW9 A;  2LD7 A;  1GJJ A;  2DK4 A;  1ZBH A;  1A63 A;  2W51 A;  2JVW A;  2ODG C;  3FLG A;  4UZW A;  1JEI A;  1ZS9 A;  2MPH A;  1A8V A;  1E7L A;  5CIU A;  2HJQ A;  1H9E A; 
#chains in the Genus database with same CATH homology
 1GKU B;  2KFV A;  1Y02 A;  2G80 A;  1GL9 B;  1YNS A;  2LC3 A;  2QNF A;  2A8V A;  1H9F A;  1EN7 A;  1E7D A;  2QNC A;  2ODC I;  1A62 A;  3L0O A;  2LD7 A;  1GJJ A;  2DK4 A;  1A63 A;  2W51 A;  2ODG C;  1JEI A;  1ZS9 A;  2MPH A;  1A8V A;  1E7L A;  2HJQ A;  1H9E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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