1GK0A

Structure-based prediction of modifications in glutarylamidase to allow single-step enzymatic production of 7-aminocephalosporanic acid from cephalosporin c
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
153
structure length
153
Chain Sequence
QAPIAAYKPRSNEILWDGYGVPHIYGVDAPSAFYGYGWAQARSHGDNILRLYGEARGKGAEYWGPDYEQTTVWLLTNGVPERAQQWYAQQSPDFRANLDAFAAGINAYAQQNPDDISPEVRQVLPVSGADVVAHAHRLMNFLYVASPGRTLGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Prediction of Modifications in Glutarylamidase to Allow Single-Step Enzymatic Production of 7-Aminocephalosporanic Acid from Cephalosporin C.
pubmed doi rcsb
molecule tags Hydrolase
source organism Pseudomonas sp.
molecule keywords CEPHALOSPORIN ACYLASE
total genus 49
structure length 153
sequence length 153
chains with identical sequence C
ec nomenclature ec 3.5.1.93: Glutaryl-7-aminocephalosporanic-acid acylase.
pdb deposition date 2001-08-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.439.10 Mainly Alpha Orthogonal Bundle Penicillin Amidohydrolase; domain 1 Penicillin Amidohydrolase, domain 1 1gk0A00
3SRBA 1GK1A 1GM7A 1OR0A 4K2FA 2WYBA 3L91A 2ADVA 1PNKA 4YFAA 1AJNA 1JW0A 4HSTA 1CP9A 2WYCA 4HSRA 4PEMA 4WKTA 1KEHA 4YFBA 4WKVA 1KECA 1PNMA 2WYEA 1K7DA 3JTRA 1K5SA 1AI7A 1AI5A 3JTQA 3K3WA 3ML0A 4PELA 4YF9A 1FM2A 1H2GA 3L94A 1AI4A 2AE4A 4E55A 4E56A 3SRCA 1E3AA 1PNLA 1GKFA 2AE3A 1K5QA 1GK9A 4E57A 2WYDA 2AE5A 4M1JA 1GM9A 4BTHA 1AI6A 4WKUA 1FXHA 1GK0A 3SRAA 4K2GA 1GM8A 1FXVA 1JVZA 4WKSA 1JX9A 3S8RA 1AJPA 1AJQA 1GHDA
chains in the Genus database with same CATH superfamily
3SRBA 1GK1A 1GM7A 1OR0A 4K2FA 2WYBA 3L91A 2ADVA 1PNKA 4YFAA 1AJNA 1JW0A 4HSTA 1CP9A 2WYCA 4HSRA 4PEMA 4WKTA 1KEHA 4YFBA 4WKVA 1KECA 1PNMA 2WYEA 1K7DA 3JTRA 1K5SA 1AI7A 1AI5A 3JTQA 3K3WA 3ML0A 4PELA 4YF9A 1FM2A 1H2GA 3L94A 1AI4A 2AE4A 4E55A 4E56A 3SRCA 1E3AA 1PNLA 1GKFA 2AE3A 1K5QA 1GK9A 4E57A 3FGRA 2WYDA 2AE5A 4M1JA 1GM9A 4BTHA 1AI6A 4WKUA 4BWCA 1FXHA 1GK0A 3SRAA 4K2GA 1GM8A 1FXVA 1JVZA 4WKSA 1JX9A 3FGTA 1AJPA 3S8RA 1AJQA 1GHDA
chains in the Genus database with same CATH topology
3SRBA 1GK1A 1GM7A 1OR0A 4K2FA 2WYBA 3L91A 2ADVA 1PNKA 4YFAA 1AJNA 1JW0A 4HSTA 1CP9A 2WYCA 4HSRA 4PEMA 4WKTA 1KEHA 4YFBA 4WKVA 1KECA 1PNMA 2WYEA 1K7DA 3JTRA 1K5SA 1AI7A 1AI5A 3JTQA 3K3WA 3ML0A 4PELA 4YF9A 1FM2A 1H2GA 3L94A 1AI4A 2AE4A 4E55A 4E56A 3SRCA 1E3AA 1PNLA 1GKFA 2AE3A 1K5QA 1GK9A 4E57A 2WYDA 2AE5A 4M1JA 1GM9A 4BTHA 1AI6A 4WKUA 1FXHA 1GK0A 3SRAA 4K2GA 1GM8A 1FXVA 1JVZA 4WKSA 1JX9A 3S8RA 1AJPA 1AJQA 1GHDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SRB A;  1GK1 A;  1GM7 A;  1OR0 A;  4K2F A;  2WYB A;  3L91 A;  2ADV A;  1PNK A;  4YFA A;  1AJN A;  1JW0 A;  4HST A;  1CP9 A;  2WYC A;  4HSR A;  4PEM A;  4WKT A;  1KEH A;  4YFB A;  4WKV A;  1KEC A;  1PNM A;  2WYE A;  1K7D A;  3JTR A;  1K5S A;  1AI7 A;  1AI5 A;  3JTQ A;  3K3W A;  3ML0 A;  4PEL A;  4YF9 A;  1FM2 A;  1H2G A;  3L94 A;  1AI4 A;  2AE4 A;  4E55 A;  4E56 A;  3SRC A;  1E3A A;  1PNL A;  1GKF A;  2AE3 A;  1K5Q A;  1GK9 A;  4E57 A;  2WYD A;  2AE5 A;  4M1J A;  1GM9 A;  4BTH A;  1AI6 A;  4WKU A;  1FXH A;  1GK0 A;  3SRA A;  4K2G A;  1GM8 A;  1FXV A;  1JVZ A;  4WKS A;  1JX9 A;  3S8R A;  1AJP A;  1AJQ A;  1GHD A; 
#chains in the Genus database with same CATH topology
 3SRB A;  1GK1 A;  1GM7 A;  1OR0 A;  4K2F A;  2WYB A;  3L91 A;  2ADV A;  1PNK A;  4YFA A;  1AJN A;  1JW0 A;  4HST A;  1CP9 A;  2WYC A;  4HSR A;  4PEM A;  4WKT A;  1KEH A;  4YFB A;  4WKV A;  1KEC A;  1PNM A;  2WYE A;  1K7D A;  3JTR A;  1K5S A;  1AI7 A;  1AI5 A;  3JTQ A;  3K3W A;  3ML0 A;  4PEL A;  4YF9 A;  1FM2 A;  1H2G A;  3L94 A;  1AI4 A;  2AE4 A;  4E55 A;  4E56 A;  3SRC A;  1E3A A;  1PNL A;  1GKF A;  2AE3 A;  1K5Q A;  1GK9 A;  4E57 A;  3FGR A;  2WYD A;  2AE5 A;  4M1J A;  1GM9 A;  4BTH A;  1AI6 A;  4WKU A;  4BWC A;  1FXH A;  1GK0 A;  3SRA A;  4K2G A;  1GM8 A;  1FXV A;  1JVZ A;  4WKS A;  1JX9 A;  3FGT A;  1AJP A;  3S8R A;  1AJQ A;  1GHD A; 
#chains in the Genus database with same CATH homology
 3SRB A;  1GK1 A;  1GM7 A;  1OR0 A;  4K2F A;  2WYB A;  3L91 A;  2ADV A;  1PNK A;  4YFA A;  1AJN A;  1JW0 A;  4HST A;  1CP9 A;  2WYC A;  4HSR A;  4PEM A;  4WKT A;  1KEH A;  4YFB A;  4WKV A;  1KEC A;  1PNM A;  2WYE A;  1K7D A;  3JTR A;  1K5S A;  1AI7 A;  1AI5 A;  3JTQ A;  3K3W A;  3ML0 A;  4PEL A;  4YF9 A;  1FM2 A;  1H2G A;  3L94 A;  1AI4 A;  2AE4 A;  4E55 A;  4E56 A;  3SRC A;  1E3A A;  1PNL A;  1GKF A;  2AE3 A;  1K5Q A;  1GK9 A;  4E57 A;  2WYD A;  2AE5 A;  4M1J A;  1GM9 A;  4BTH A;  1AI6 A;  4WKU A;  1FXH A;  1GK0 A;  3SRA A;  4K2G A;  1GM8 A;  1FXV A;  1JVZ A;  4WKS A;  1JX9 A;  3S8R A;  1AJP A;  1AJQ A;  1GHD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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