1GYGA

R32 closed form of alpha-toxin from clostridium perfringens strain cer89l43
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
370
structure length
370
Chain Sequence
WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFSKDNSWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTVGCKTNEDFYADILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFPDAYKPENIKVIANGKVVVDKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the C. Perfringens Alpha-Toxin with the Active Site Closed by a Flexible Loop Region
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords PHOSPHOLIPASE C
total genus 131
structure length 370
sequence length 370
chains with identical sequence B
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2002-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1gygA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1gygA02
5FBGA 4JDGA 1QM6A 2FGNA 3FG1A 1GPLA 4CXPA 1F8NA 1LPBB 1P6DA 3BNDA 1OLPA 1FGQA 3BNBA 2OXEA 1LNHA 2PPLA 3V92A 1AK0A 3W52A 3VF1A 1LPAB 4QWTA 4CXOA 2IUKA 1ETHA 5FBFA 1FGMA 1LOXA 1FGOA 1QMDA 3O8YA 1N8SA 3CWZB 1P6EA 1W52X 4CWMA 3V98A 1HU9A 4CXVA 1ROVA 2HUCA 4DJ4A 1AH7A 1RRHA 3FG4A 1GYGA 2FFZA 1RP1A 1Y4KA 4WHAA 1RRLA 1P5XA 5FB9A 5EEOA 1KHOA 1IK3A 1BU8A 3BNCA 1YGEA 2WY6A 3SNGA 2PVSA 2WXTA 3BNEA 3FG3A 4NREA 2IUJA 1N8QA 2SBLA 5FBDA 2FNQA 5FBCA 2WXUA 1CA1A 1JNQA 3PZWA 3V99A 5FBBA 1FGRA 1FGTA 1NO3A 5FBAA 2P0MA 4WFOA 1HPLA
chains in the Genus database with same CATH superfamily
2XFEA 5FBGA 4JDGA 1QM6A 2FGNA 3FG1A 1GPLA 4CXPA 1F8NA 1LPBB 1P6DA 4QEYA 3BNDA 1OLPA 3U6GA 1FGQA 3BNBA 2OXEA 1LNHA 2PPLA 3V92A 1AK0A 3W52A 3VF1A 1LPAB 4QWTA 4CXOA 3IBZA 2IUKA 1ETHA 5FBFA 1FGMA 1LOXA 1FGOA 1QMDA 3O8YA 1N8SA 3CWZB 1P6EA 1W52X 4CWMA 3V98A 1HU9A 4CXVA 1ROVA 2HUCA 4DJ4A 1AH7A 1RRHA 3FG4A 1GYGA 2FFZA 1RP1A 1Y4KA 4WHAA 2XHJA 1RRLA 2QZ7A 1P5XA 2LG7A 5FB9A 5EEOA 1KHOA 2XFDA 2KXTA 1IK3A 2LGEA 1BU8A 3BNCA 2XHHA 1YGEA 2WY6A 3SNGA 2PVSA 2WXTA 3BNEA 2KXVA 3FG3A 4NREA 2IUJA 1N8QA 2SBLA 2QNGA 5FBDA 2FNQA 5FBCA 2WXUA 1CA1A 1JNQA 3PZWA 2LRGA 3V99A 5FBBA 1FGRA 1FGTA 1NO3A 5FBAA 2P0MA 4WFOA 1HPLA
chains in the Genus database with same CATH topology
5FBGA 4JDGA 1QM6A 2FGNA 3FG1A 1GPLA 4CXPA 1F8NA 1LPBB 1P6DA 3BNDA 1OLPA 1FGQA 3BNBA 2OXEA 1LNHA 2PPLA 3V92A 1AK0A 3W52A 3VF1A 1LPAB 4QWTA 4CXOA 2IUKA 1ETHA 5FBFA 1FGMA 1LOXA 1FGOA 1QMDA 3O8YA 1N8SA 3CWZB 1P6EA 1W52X 4CWMA 3V98A 1HU9A 4CXVA 1ROVA 2HUCA 4DJ4A 1AH7A 1RRHA 3FG4A 1GYGA 2FFZA 1RP1A 1Y4KA 4WHAA 1RRLA 1P5XA 5FB9A 5EEOA 1KHOA 1IK3A 1BU8A 3BNCA 1YGEA 2WY6A 3SNGA 2PVSA 2WXTA 3BNEA 3FG3A 4NREA 2IUJA 1N8QA 2SBLA 5FBDA 2FNQA 5FBCA 2WXUA 1CA1A 1JNQA 3PZWA 3V99A 5FBBA 1FGRA 1FGTA 1NO3A 5FBAA 2P0MA 4WFOA 1HPLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FBG A;  4JDG A;  1QM6 A;  2FGN A;  3FG1 A;  1GPL A;  4CXP A;  1F8N A;  1LPB B;  1P6D A;  3BND A;  1OLP A;  1FGQ A;  3BNB A;  2OXE A;  1LNH A;  2PPL A;  3V92 A;  1AK0 A;  3W52 A;  3VF1 A;  1LPA B;  4QWT A;  4CXO A;  2IUK A;  1ETH A;  5FBF A;  1FGM A;  1LOX A;  1FGO A;  1QMD A;  3O8Y A;  1N8S A;  3CWZ B;  1P6E A;  1W52 X;  4CWM A;  3V98 A;  1HU9 A;  4CXV A;  1ROV A;  2HUC A;  4DJ4 A;  1AH7 A;  1RRH A;  3FG4 A;  1GYG A;  2FFZ A;  1RP1 A;  1Y4K A;  4WHA A;  1RRL A;  1P5X A;  5FB9 A;  5EEO A;  1KHO A;  1IK3 A;  1BU8 A;  3BNC A;  1YGE A;  2WY6 A;  3SNG A;  2PVS A;  2WXT A;  3BNE A;  3FG3 A;  4NRE A;  2IUJ A;  1N8Q A;  2SBL A;  5FBD A;  2FNQ A;  5FBC A;  2WXU A;  1CA1 A;  1JNQ A;  3PZW A;  3V99 A;  5FBB A;  1FGR A;  1FGT A;  1NO3 A;  5FBA A;  2P0M A;  4WFO A;  1HPL A; 
#chains in the Genus database with same CATH topology
 2XFE A;  5FBG A;  4JDG A;  1QM6 A;  2FGN A;  3FG1 A;  1GPL A;  4CXP A;  1F8N A;  1LPB B;  1P6D A;  4QEY A;  3BND A;  1OLP A;  3U6G A;  1FGQ A;  3BNB A;  2OXE A;  1LNH A;  2PPL A;  3V92 A;  1AK0 A;  3W52 A;  3VF1 A;  1LPA B;  4QWT A;  4CXO A;  3IBZ A;  2IUK A;  1ETH A;  5FBF A;  1FGM A;  1LOX A;  1FGO A;  1QMD A;  3O8Y A;  1N8S A;  3CWZ B;  1P6E A;  1W52 X;  4CWM A;  3V98 A;  1HU9 A;  4CXV A;  1ROV A;  2HUC A;  4DJ4 A;  1AH7 A;  1RRH A;  3FG4 A;  1GYG A;  2FFZ A;  1RP1 A;  1Y4K A;  4WHA A;  2XHJ A;  1RRL A;  2QZ7 A;  1P5X A;  2LG7 A;  5FB9 A;  5EEO A;  1KHO A;  2XFD A;  2KXT A;  1IK3 A;  2LGE A;  1BU8 A;  3BNC A;  2XHH A;  1YGE A;  2WY6 A;  3SNG A;  2PVS A;  2WXT A;  3BNE A;  2KXV A;  3FG3 A;  4NRE A;  2IUJ A;  1N8Q A;  2SBL A;  2QNG A;  5FBD A;  2FNQ A;  5FBC A;  2WXU A;  1CA1 A;  1JNQ A;  3PZW A;  2LRG A;  3V99 A;  5FBB A;  1FGR A;  1FGT A;  1NO3 A;  5FBA A;  2P0M A;  4WFO A;  1HPL A; 
#chains in the Genus database with same CATH homology
 5FBG A;  4JDG A;  1QM6 A;  2FGN A;  3FG1 A;  1GPL A;  4CXP A;  1F8N A;  1LPB B;  1P6D A;  3BND A;  1OLP A;  1FGQ A;  3BNB A;  2OXE A;  1LNH A;  2PPL A;  3V92 A;  1AK0 A;  3W52 A;  3VF1 A;  1LPA B;  4QWT A;  4CXO A;  2IUK A;  1ETH A;  5FBF A;  1FGM A;  1LOX A;  1FGO A;  1QMD A;  3O8Y A;  1N8S A;  3CWZ B;  1P6E A;  1W52 X;  4CWM A;  3V98 A;  1HU9 A;  4CXV A;  1ROV A;  2HUC A;  4DJ4 A;  1AH7 A;  1RRH A;  3FG4 A;  1GYG A;  2FFZ A;  1RP1 A;  1Y4K A;  4WHA A;  1RRL A;  1P5X A;  5FB9 A;  5EEO A;  1KHO A;  1IK3 A;  1BU8 A;  3BNC A;  1YGE A;  2WY6 A;  3SNG A;  2PVS A;  2WXT A;  3BNE A;  3FG3 A;  4NRE A;  2IUJ A;  1N8Q A;  2SBL A;  5FBD A;  2FNQ A;  5FBC A;  2WXU A;  1CA1 A;  1JNQ A;  3PZW A;  3V99 A;  5FBB A;  1FGR A;  1FGT A;  1NO3 A;  5FBA A;  2P0M A;  4WFO A;  1HPL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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