1H9ZA

Human serum albumin complexed with myristic acid and the r-(+) enantiomer of warfarin
Total Genus 224
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords SERUM ALBUMIN
publication title Crystal Structure Analysis of Warfarin Binding to Human Serum Albumin: Anatomy of Drug Site I
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 224
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2001-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA05
4ZBQA 4IW2A 1HK1A 3TDLA 3V09A 4ZBRA 4HGMB 1E7FA 4N0FD 4K71A 4LA0A 1HK3A 5ID9A 1MA9A 4EMXA 5IIHA 2XVWA 1KXPD 1E78A 2XVUA 2VUFA 4F5UA 1E7IA 4L9KA 4G04A 3LU7A 1O9XA 1UORA 4F5SA 2XW0A 3V08A 4J2VA 5IJFA 4F5TA 4OR0A 5IFOA 4IW1A 4L9QA 5IJEA 5DBYA 1E7BA 1LOTA 4N0UD 2XSIA 3V03A 4LB2A 1E7GA 4LB9A 2BXDA 1BJ5A 2BXFA 1E7EA 4E99A 1H9ZA 2VDBA 2XVQA 3SQJA 4K2CA 2BXMA 4BKEA 2BXNA 2VUEA 2BXAA 2BXGA 4L8UA 1AO6A 5IIXA 2I30A 4HGKA 3JRYA 4LUHA 5FUOA 3LU8A 5GHKA 3B9LA 4JK4A 1BM0A 2XVVA 2BXLA 1J7EA 1HA2A 1E7CA 2BXBA 1GNIA 2YDFA 1TF0A 4PO0A 3JQZA 1E7AA 2BXHA 1E7HA 2BXIA 1HK5A 5ID7A 1BKEA 2XW1A 2BXEA 5HOZA 1HK4A 4LUFA 3LU6A 2I2ZA 1HK2A 4G03A 4S1YA 4OT2A 3CX9A 3UIVA 2BXPA 1KW2A 2BXKA 1GNJA 4Z69A 5IJ5A 2BXCA 3A73A 1J78A 4F5VA 2BXQA 1N5UA 5IIUA 3B9MA 5DQFA 2BX8A 2BXOA
chains in the Genus database with same CATH superfamily
4ZBQA 4IW2A 1HK1A 3TDLA 2LQIA 3V09A 1KDXA 4ZBRA 2V36A 3G9KD 5B5TA 4HGMB 3H37A 1E7FA 3SIVB 4N0FD 4K71A 4GDXA 1HK3A 2KWFA 4LA0A 5BPKA 2ROHA 5ID9A 4N3ZA 2K0NA 1MA9A 4EMXA 5IIHA 2XVWA 1KXPD 1NT2B 2LOQA 1E78A 1MIWA 4TQ1A 2DYOA 2AGHB 1MM8A 1MUSA 2XVUA 2VUFA 1H5WA 3VQIA 4F5UA 5GIPA 4DHXB 1SB0A 1FOUA 2OZBB 1E7IA 3GQUA 4L9KA 2LXTA 3M99C 2DG5A 2QHBA 3KJLA 4G01A 3NVMA 3H3AA 4G04A 3LU7A 4D7XA 2QMCA 1O9XA 1UORA 2OT3A 1TXUA 4F5SA 2XW0A 1IJGA 3MHSB 3V08A 4J2VA 4M70B 4OTTA 4WA6B 5IJFA 4F5TA 4OR0A 2EFEA 5IFOA 1VFIA 2KBZA 4IW1A 3FNMA 2EFDA 4L9QA 2Z8IA 3WHSA 5IJEA 5GIOA 5DBYA 1MUHA 1E7BA 1LOTA 4N0UD 4ZCGA 2LQHA 1VZSA 2XSIA 3GQXA 3V03A 4LB2A 1E7GA 4LB9A 5GINA 2BXDA 2Z8JA 1BJ5A 2BXFA 2GUTA 2EFHA 4NAWB 1E7EA 4E99A 1H9ZA 4ZUXV 2VDBA 2XVQA 4TQ0A 3SQJA 2DYMA 2BXMA 2DBXA 2E0YA 4K2CA 4BKEA 2BXNA 2VUEA 1JNBA 3NMUA 4DM0A 2BXAA 2BXGA 3MHHB 4L8UA 2E0XA 1AO6A 5IIXA 2I30A 3GA9L 3JRYA 4FK5B 4HGKA 2AJEA 4LUHA 4OTUA 3LU8A 5GHKA 3FWCC 5FUOA 3B9LA 2DBUA 3ECPA 3SIUB 4JK4A 1BM0A 2XVVA 2BXLA 5D7GA 1J7EA 1HA2A 3WHRA 3WHQA 1E7CA 2CKXA 2LXSA 2BXBA 1GNIA 3NVKA 3W1SA 3NVIA 4GDKB 2YDFA 1TF0A 4PO0A 4ZC6A 3JQZA 1E7AA 4GG2A 2BXHA 1E7HA 2BXIA 1HK5A 4Z9OA 4BY9C 4FIPB 5ID7A 1BKEA 3FWBC 4I9OA 3ICXA 4GDLB 2XW1A 2BXEA 5HOZA 1HK4A 4LUFA 4W4UB 3BPJA 3LU6A 2XMOA 2I2ZA 1HK2A 4G03A 4MBEC 4S1YA 4OT2A 3CX9A 3UIVA 2BXPA 1KW2A 2DBWA 2BXKA 1GNJA 4Z69A 1MIYA 4C31B 5IJ5A 1LNSA 2JUHA 2NQOA 2Z8KA 2BXCA 2QM6A 3A73A 3PLAA 2NNWA 1J78A 2EFCA 3KIKA 4FJCB 4F5VA 2BXQA 1N5UA 5IIUA 1MIVA 3B9MA 2BX8A 5DQFA 4ZBKA 3A75A 2BXOA
chains in the Genus database with same CATH topology
4ZBQA 4IW2A 1HK1A 3TDLA 3V09A 4ZBRA 2V36A 3G9KD 5B5TA 4HGMB 3H37A 1E7FA 3SIVB 4N0FD 4K71A 4GDXA 1HK3A 4LA0A 5BPKA 2ROHA 5ID9A 4N3ZA 1MA9A 4EMXA 5IIHA 2XVWA 1KXPD 1NT2B 2LOQA 1E78A 1MIWA 4TQ1A 2DYOA 2XVUA 2VUFA 1H5WA 3VQIA 4F5UA 5GIPA 4DHXB 1FOUA 2OZBB 1E7IA 3GQUA 4L9KA 3M99C 2DG5A 2QHBA 3KJLA 4G01A 3NVMA 3H3AA 4G04A 3LU7A 2QMCA 1O9XA 1UORA 2OT3A 1TXUA 4F5SA 2XW0A 1IJGA 3MHSB 3V08A 4J2VA 4M70B 4OTTA 4WA6B 5IJFA 4F5TA 4OR0A 2EFEA 5IFOA 1VFIA 2KBZA 4IW1A 3FNMA 2EFDA 4L9QA 2Z8IA 3WHSA 5IJEA 5GIOA 5DBYA 1E7BA 1LOTA 4N0UD 4ZCGA 2XSIA 1VZSA 3GQXA 3V03A 4LB2A 1E7GA 4LB9A 5GINA 2BXDA 2Z8JA 1BJ5A 2BXFA 2EFHA 4NAWB 1E7EA 4E99A 1H9ZA 4ZUXV 2VDBA 2XVQA 4TQ0A 3SQJA 2DYMA 2BXMA 2DBXA 2E0YA 4K2CA 4BKEA 2BXNA 2VUEA 1JNBA 3NMUA 2BXAA 2BXGA 3MHHB 4L8UA 2E0XA 1AO6A 5IIXA 2I30A 3GA9L 3JRYA 4FK5B 4HGKA 2AJEA 4LUHA 4OTUA 3LU8A 5GHKA 3FWCC 5FUOA 3B9LA 2DBUA 3SIUB 4JK4A 1BM0A 2XVVA 2BXLA 5D7GA 1J7EA 1HA2A 3WHRA 3WHQA 1E7CA 2CKXA 2BXBA 1GNIA 3NVKA 3W1SA 3NVIA 4GDKB 2YDFA 1TF0A 4PO0A 4ZC6A 3JQZA 1E7AA 4GG2A 2BXHA 1E7HA 2BXIA 1HK5A 4Z9OA 4BY9C 4FIPB 5ID7A 1BKEA 3FWBC 3ICXA 4GDLB 2XW1A 2BXEA 5HOZA 1HK4A 4LUFA 4W4UB 3LU6A 2XMOA 2I2ZA 1HK2A 4G03A 4MBEC 4S1YA 4OT2A 3CX9A 3UIVA 2BXPA 1KW2A 2DBWA 2BXKA 1GNJA 4Z69A 1MIYA 4C31B 5IJ5A 1LNSA 2JUHA 2NQOA 2Z8KA 2BXCA 2QM6A 3A73A 3PLAA 2NNWA 1J78A 2EFCA 3KIKA 4FJCB 4F5VA 2BXQA 1N5UA 5IIUA 1MIVA 3B9MA 2BX8A 5DQFA 4ZBKA 3A75A 2BXOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZBQ A;  4IW2 A;  1HK1 A;  3TDL A;  3V09 A;  4ZBR A;  4HGM B;  1E7F A;  4N0F D;  4K71 A;  4LA0 A;  1HK3 A;  5ID9 A;  1MA9 A;  4EMX A;  5IIH A;  2XVW A;  1KXP D;  1E78 A;  2XVU A;  2VUF A;  4F5U A;  1E7I A;  4L9K A;  4G04 A;  3LU7 A;  1O9X A;  1UOR A;  4F5S A;  2XW0 A;  3V08 A;  4J2V A;  5IJF A;  4F5T A;  4OR0 A;  5IFO A;  4IW1 A;  4L9Q A;  5IJE A;  5DBY A;  1E7B A;  1LOT A;  4N0U D;  2XSI A;  3V03 A;  4LB2 A;  1E7G A;  4LB9 A;  2BXD A;  1BJ5 A;  2BXF A;  1E7E A;  4E99 A;  1H9Z A;  2VDB A;  2XVQ A;  3SQJ A;  4K2C A;  2BXM A;  4BKE A;  2BXN A;  2VUE A;  2BXA A;  2BXG A;  4L8U A;  1AO6 A;  5IIX A;  2I30 A;  4HGK A;  3JRY A;  4LUH A;  5FUO A;  3LU8 A;  5GHK A;  3B9L A;  4JK4 A;  1BM0 A;  2XVV A;  2BXL A;  1J7E A;  1HA2 A;  1E7C A;  2BXB A;  1GNI A;  2YDF A;  1TF0 A;  4PO0 A;  3JQZ A;  1E7A A;  2BXH A;  1E7H A;  2BXI A;  1HK5 A;  5ID7 A;  1BKE A;  2XW1 A;  2BXE A;  5HOZ A;  1HK4 A;  4LUF A;  3LU6 A;  2I2Z A;  1HK2 A;  4G03 A;  4S1Y A;  4OT2 A;  3CX9 A;  3UIV A;  2BXP A;  1KW2 A;  2BXK A;  1GNJ A;  4Z69 A;  5IJ5 A;  2BXC A;  3A73 A;  1J78 A;  4F5V A;  2BXQ A;  1N5U A;  5IIU A;  3B9M A;  5DQF A;  2BX8 A;  2BXO A; 
#chains in the Genus database with same CATH topology
 4ZBQ A;  4IW2 A;  1HK1 A;  3TDL A;  2LQI A;  3V09 A;  1KDX A;  4ZBR A;  2V36 A;  3G9K D;  5B5T A;  4HGM B;  3H37 A;  1E7F A;  3SIV B;  4N0F D;  4K71 A;  4GDX A;  1HK3 A;  2KWF A;  4LA0 A;  5BPK A;  2ROH A;  5ID9 A;  4N3Z A;  2K0N A;  1MA9 A;  4EMX A;  5IIH A;  2XVW A;  1KXP D;  1NT2 B;  2LOQ A;  1E78 A;  1MIW A;  4TQ1 A;  2DYO A;  2AGH B;  1MM8 A;  1MUS A;  2XVU A;  2VUF A;  1H5W A;  3VQI A;  4F5U A;  5GIP A;  4DHX B;  1SB0 A;  1FOU A;  2OZB B;  1E7I A;  3GQU A;  4L9K A;  2LXT A;  3M99 C;  2DG5 A;  2QHB A;  3KJL A;  4G01 A;  3NVM A;  3H3A A;  4G04 A;  3LU7 A;  4D7X A;  2QMC A;  1O9X A;  1UOR A;  2OT3 A;  1TXU A;  4F5S A;  2XW0 A;  1IJG A;  3MHS B;  3V08 A;  4J2V A;  4M70 B;  4OTT A;  4WA6 B;  5IJF A;  4F5T A;  4OR0 A;  2EFE A;  5IFO A;  1VFI A;  2KBZ A;  4IW1 A;  3FNM A;  2EFD A;  4L9Q A;  2Z8I A;  3WHS A;  5IJE A;  5GIO A;  5DBY A;  1MUH A;  1E7B A;  1LOT A;  4N0U D;  4ZCG A;  2LQH A;  1VZS A;  2XSI A;  3GQX A;  3V03 A;  4LB2 A;  1E7G A;  4LB9 A;  5GIN A;  2BXD A;  2Z8J A;  1BJ5 A;  2BXF A;  2GUT A;  2EFH A;  4NAW B;  1E7E A;  4E99 A;  1H9Z A;  4ZUX V;  2VDB A;  2XVQ A;  4TQ0 A;  3SQJ A;  2DYM A;  2BXM A;  2DBX A;  2E0Y A;  4K2C A;  4BKE A;  2BXN A;  2VUE A;  1JNB A;  3NMU A;  4DM0 A;  2BXA A;  2BXG A;  3MHH B;  4L8U A;  2E0X A;  1AO6 A;  5IIX A;  2I30 A;  3GA9 L;  3JRY A;  4FK5 B;  4HGK A;  2AJE A;  4LUH A;  4OTU A;  3LU8 A;  5GHK A;  3FWC C;  5FUO A;  3B9L A;  2DBU A;  3ECP A;  3SIU B;  4JK4 A;  1BM0 A;  2XVV A;  2BXL A;  5D7G A;  1J7E A;  1HA2 A;  3WHR A;  3WHQ A;  1E7C A;  2CKX A;  2LXS A;  2BXB A;  1GNI A;  3NVK A;  3W1S A;  3NVI A;  4GDK B;  2YDF A;  1TF0 A;  4PO0 A;  4ZC6 A;  3JQZ A;  1E7A A;  4GG2 A;  2BXH A;  1E7H A;  2BXI A;  1HK5 A;  4Z9O A;  4BY9 C;  4FIP B;  5ID7 A;  1BKE A;  3FWB C;  4I9O A;  3ICX A;  4GDL B;  2XW1 A;  2BXE A;  5HOZ A;  1HK4 A;  4LUF A;  4W4U B;  3BPJ A;  3LU6 A;  2XMO A;  2I2Z A;  1HK2 A;  4G03 A;  4MBE C;  4S1Y A;  4OT2 A;  3CX9 A;  3UIV A;  2BXP A;  1KW2 A;  2DBW A;  2BXK A;  1GNJ A;  4Z69 A;  1MIY A;  4C31 B;  5IJ5 A;  1LNS A;  2JUH A;  2NQO A;  2Z8K A;  2BXC A;  2QM6 A;  3A73 A;  3PLA A;  2NNW A;  1J78 A;  2EFC A;  3KIK A;  4FJC B;  4F5V A;  2BXQ A;  1N5U A;  5IIU A;  1MIV A;  3B9M A;  2BX8 A;  5DQF A;  4ZBK A;  3A75 A;  2BXO A; 
#chains in the Genus database with same CATH homology
 4ZBQ A;  4IW2 A;  1HK1 A;  3TDL A;  3V09 A;  4ZBR A;  2V36 A;  3G9K D;  5B5T A;  4HGM B;  3H37 A;  1E7F A;  3SIV B;  4N0F D;  4K71 A;  4GDX A;  1HK3 A;  4LA0 A;  5BPK A;  2ROH A;  5ID9 A;  4N3Z A;  1MA9 A;  4EMX A;  5IIH A;  2XVW A;  1KXP D;  1NT2 B;  2LOQ A;  1E78 A;  1MIW A;  4TQ1 A;  2DYO A;  2XVU A;  2VUF A;  1H5W A;  3VQI A;  4F5U A;  5GIP A;  4DHX B;  1FOU A;  2OZB B;  1E7I A;  3GQU A;  4L9K A;  3M99 C;  2DG5 A;  2QHB A;  3KJL A;  4G01 A;  3NVM A;  3H3A A;  4G04 A;  3LU7 A;  2QMC A;  1O9X A;  1UOR A;  2OT3 A;  1TXU A;  4F5S A;  2XW0 A;  1IJG A;  3MHS B;  3V08 A;  4J2V A;  4M70 B;  4OTT A;  4WA6 B;  5IJF A;  4F5T A;  4OR0 A;  2EFE A;  5IFO A;  1VFI A;  2KBZ A;  4IW1 A;  3FNM A;  2EFD A;  4L9Q A;  2Z8I A;  3WHS A;  5IJE A;  5GIO A;  5DBY A;  1E7B A;  1LOT A;  4N0U D;  4ZCG A;  2XSI A;  1VZS A;  3GQX A;  3V03 A;  4LB2 A;  1E7G A;  4LB9 A;  5GIN A;  2BXD A;  2Z8J A;  1BJ5 A;  2BXF A;  2EFH A;  4NAW B;  1E7E A;  4E99 A;  1H9Z A;  4ZUX V;  2VDB A;  2XVQ A;  4TQ0 A;  3SQJ A;  2DYM A;  2BXM A;  2DBX A;  2E0Y A;  4K2C A;  4BKE A;  2BXN A;  2VUE A;  1JNB A;  3NMU A;  2BXA A;  2BXG A;  3MHH B;  4L8U A;  2E0X A;  1AO6 A;  5IIX A;  2I30 A;  3GA9 L;  3JRY A;  4FK5 B;  4HGK A;  2AJE A;  4LUH A;  4OTU A;  3LU8 A;  5GHK A;  3FWC C;  5FUO A;  3B9L A;  2DBU A;  3SIU B;  4JK4 A;  1BM0 A;  2XVV A;  2BXL A;  5D7G A;  1J7E A;  1HA2 A;  3WHR A;  3WHQ A;  1E7C A;  2CKX A;  2BXB A;  1GNI A;  3NVK A;  3W1S A;  3NVI A;  4GDK B;  2YDF A;  1TF0 A;  4PO0 A;  4ZC6 A;  3JQZ A;  1E7A A;  4GG2 A;  2BXH A;  1E7H A;  2BXI A;  1HK5 A;  4Z9O A;  4BY9 C;  4FIP B;  5ID7 A;  1BKE A;  3FWB C;  3ICX A;  4GDL B;  2XW1 A;  2BXE A;  5HOZ A;  1HK4 A;  4LUF A;  4W4U B;  3LU6 A;  2XMO A;  2I2Z A;  1HK2 A;  4G03 A;  4MBE C;  4S1Y A;  4OT2 A;  3CX9 A;  3UIV A;  2BXP A;  1KW2 A;  2DBW A;  2BXK A;  1GNJ A;  4Z69 A;  1MIY A;  4C31 B;  5IJ5 A;  1LNS A;  2JUH A;  2NQO A;  2Z8K A;  2BXC A;  2QM6 A;  3A73 A;  3PLA A;  2NNW A;  1J78 A;  2EFC A;  3KIK A;  4FJC B;  4F5V A;  2BXQ A;  1N5U A;  5IIU A;  1MIV A;  3B9M A;  2BX8 A;  5DQF A;  4ZBK A;  3A75 A;  2BXO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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