1HM2A

Active site of chondroitinase ac lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis
Total Genus 239
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
239
sequence length
674
structure length
674
Chain Sequence
b'GTAELIMKRVMLDLKKPLRNMDKVAEKNLNTLQPDGSWKDVPYKDDAMTNWLPNNHLLQLETIIQAYIEKDSHYYGDDKVFDQISKAFKYWYDSDPKSRNWWHNEIATPQALGEMLILMRYGKKPLDEALVHKLTERMKRGEPEKKTGANKTDIALHYFYRALLTSDEALLSFAVKELFYPVQFVHYEEGLQYDYSYLQHGPQLQISSYGAVFITGVLKLANYVRDTPYALSTEKLAIFSKYYRDSYLKAIRGSYMDFNVEGRGVSRPDILNKKAEKKRLLVAKMIDLKHTEEWADAIARTDSTVAAGYKIEPYHHQFWNGDYVQHLRPAYSFNVRMVSKRTRRSESGNKENLLGRYLSDGATNIQLRGPEYYNIMPVWEWDKIPGITSRDYLTDRPLTKLWGEQGSNDFAGGVSDGVYGASAYALDYDSLQAKKAWFFFDKEIVCLGAGINSNAPENITTTLNQSWLNGPVISTAGKTGRGKITTFKAQGQFWLLHDAIGYYFPEGANLSLSTQSQKGNWFHINNSHSKDEVSGDVFKLWINHGARPENAQYAYIVLPGINKPEEIKKYNGTAPKVLANTNQLQAVYHQQLDMVQAIFYTAGKLSVAGIEIETDKPCAVLIKHINGKQVIWAADPLQKEKTAVLSIRDLKTGKTNRVKIDFPQQEFAGATVEL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords CHONDROITINASE AC
publication title Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis.
pubmed doi rcsb
source organism Pedobacter heparinus
molecule tags Lyase
total genus 239
structure length 674
sequence length 674
ec nomenclature ec 4.2.2.5: Chondroitin AC lyase.
pdb deposition date 2000-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1hm2A01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1hm2A03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1hm2A02
3T2PA 1LXKA 1RWFA 2WW0A 3DECA 3E7JA 4OZWA 2E22A 4F10A 3CZJA 2WVYA 2HTBA 1QAZA 1UG9A 2CIRA 4FNVA 1JYXA 2WW2A 2JKEA 4E1YA 1YQ2A 3J7HA 3T2QA 4OZVA 1JZ5A 1RWAA 2BRVX 2D73A 1HM2A 4D6CA 1J0NA 4D6EA 3NNBA 3K25A 4OK2A 3WFAA 1F9GA 1L7JA 3IMHA 3SEPA 1NSMA 1NS2A 1YGAA 4MMIA 1MMUA 1HM3A 4D6IA 4BZFA 3VD9A 3VD3A 4BZGA 1X1JA 1ULVA 1HV6A 4D6JA 5A1AA 1OJNA 2XHNA 5JMFA 1HMWA 2WCOA 1JZ7A 3IAQA 3IAPA 2CIQA 2WMHA 2HTAA 3DCDA 3OS7A 1JZ8A 4F13A 3ECQA 3MV11 2WVXA 3NREA 1HN1A 2ZXQA 1OJPA 5E1QA 1NSRA 4BZEA 3DYOA 1X1IA 3VD5A 1X1HA 2WMFA 1K1XA 3AFLA 3NJVA 2WMJA 1NS7A 1NKGA 1NSVA 1Z45A 3I3EA 3I3DA 3MV01 4DUXA 4DUWA 4TTGA 3T08A 1N7NA 2E24A 1NS4A 3VD7A 4OK4A 2CISA 1NSUA 4D6HA 3E1F1 3VD4A 1F4AA 4D6GA 1LOHA 2WZSA 3DYPA 2FUQA 2ZQ0A 3VDCA 4DUVA 2WMGA 4AQ0A 3I3BA 3Q1NA 1JYNA 1N7OA 4MMHA 2JKPA 1L7KA 4BZHA 1F4HA 1NS8A 3T0BA 3VDAA 1NS0A 3VSNA 1TXKA 2WMKA 3T2OA 1N7QA 2Q1FA 2WMIB 1JOVA 1MMZA 1JZ4A 2FUTA 1HN0A 3MWXA 2WW3A 3NJXA 1K1WA 1RWCA 1DP0A 1LF9A 3OBAA 2WDAA 1N7RA 3VDBA 4D71A 3OB8A 3BGAA 1NSXA 1F1SA 3E80A 5JMDA 4D72A 1RW9A 4OJZA 4RNLA 1NSSA 1JZ2A 1MN0A 2WMIA 1N7PA 2JKAA 3MUY1 1RWHA 3A24A 1JZ3A 1JYVA 1PX4A 1MMXA 2WVZA 1LF6A 1SNZA 1W3YA 2X03A 1CB8A 2XSGA 1C82A 2BRWA 3NFVA 1JZ6A 1RWGA 3DYMA 1LURA 4NEIA 4D6FA 1SO0A 1J0MA 1PX3A 3T09A 1OJMA 2WVXB 3T0AA 1I8QA 1LXMA 1JYWA 3VSMA 1K1YA 1EGUA 1OJOA 2BRPA 3T0DA 1HMUA 3A0OA 2WW1A 3MUZ1 1MMYA 1NSZA 4D6DA
chains in the Genus database with same CATH superfamily
3G4DA 3Q7AB 3DECA 2FV0A 2F6DA 3ANJA 1FO3A 1O1SB 3E7JA 4OZWA 1AVLA 4F10A 3SXXA 2WVYA 1S63B 5IL8A 1IVUA 2HTBA 3SFYB 4FNQA 1TN8B 2CIRA 2CFLA 2CFGA 1JYXA 1RJOA 3M77A 1WMPA 2WOFA 2WYHA 1GA2A 1TQVA 2FUZA 1AYXA 1HM2A 3KSQB 4D6CA 2E2VA 3NNBA 3DDGA 1FBOA 4OK2A 3KBUC 1HX9A 1F9OA 1H54A 1WU6A 1R33A 3AMOB 1WMOA 1N24A 2V3PA 4MMIA 1FMIA 1TQTA 1YGAA 4EV2A 2H6GB 1MMUA 1HM3A 3P2CA 3PMMA 4RNQA 3WKHA 1HV6A 3BUBA 2PN5A 5JMFA 2RI8A 3IAQA 1SIHA 3M78A 3M00A 2NOJA 3PYBA 5IK0A 4CE7A 2GOXA 1TNUB 3DPYB 3AMOA 2ZXQA 3GZKA 2WY8A 3S4BA 1TQSA 3BVUA 3EJSA 1C3DA 3HXCB 1X1IA 4Z4JA 4KFEA 1N1BA 2H6FB 1X1HA 2VN7A 2WMFA 3AFLA 3EZ8A 3KSLB 1NKGA 3I3DA 3MV01 1N4QB 2Y74A 3CZSA 3EJUA 1IS9A 4TTGA 1LTXB 1NS4A 3HXFB 4OK4A 3S4AA 5ILIA 5ILDA 4D6HA 3VD4A 1V7VA 2IEJB 3ON6A 4JJJA 1N9EA 2WY7A 5IK6A 2WMGA 1HWWA 2BT3A 4AQ0A 3I3BA 3Q1NA 3PZ1B 3PZ3B 2KXSA 3BVWA 4EV5A 3QG0A 1JS4A 3D5SA 4Z4LA 1KSDA 3BS6A 3QRYA 3WKGA 2WMIB 1JOVA 2SQCA 2FBAA 1JZ4A 1HN0A 1KZOB 2EADA 4TF4A 1QWUA 3NJXA 3WA2X 4V1RA 2F18A 3ANKA 5IM1A 1DOGA 1RWCA 1DP0A 4FNTA 1MZCB 3G6JB 4LNVA 3TY1A 2BB6A 3SDVA 2BEDB 1JCSB 3VDBA 1XWQA 1TNBB 4RNLA 2WMIA 5IK9A 1FT2B 1GXMA 3X17A 1GAHA 1JZ3A 2B39A 3M01A 1AV4A 1QQFA 2JF4A 3SAEA 3C72B 1XW2A 1O6RA 1LF6A 1SNZA 1D6UA 5GY3A 1GSZA 1NI1B 1W3YA 4EL8A 2BRWA 3HXDB 1UT9A 1LURA 1KKTA 4ZH1A 3QFZA 3P5RA 1V5DA 4FXGB 3LVTA 1TQWA 5E2JA 1JRQA 1K1YA 4BOJA 1JCQB 3QT3A 2XFGA 3QPFA 1CEMA 2V8KA 1LVNA 1HMUA 3M74A 3X42A 2VN4A 1O6QA 1RWFA 3M76A 4BTWA 1DL2A 2OQEA 3WUXA 4J5TA 2XWJB 5EATA 3CZNA 2FYVA 1WU4A 1FBWA 3WIWA 3M02A 5FOBB 1TNYB 3X3XA 1W6KA 2JKEA 3J7HA 2XN2A 1FT1B 3KN4A 1D8DB 2CWTA 1JZ5A 3D4YA 2BRVX 3WIQA 2D73A 2YX9A 1J0NA 1LD7B 3WKIA 1N4RB 2W0QA 2GH4A 1O1RB 3IMHA 4AYOA 2ONHA 1IVXA 3WKFA 3M73A 2ONGA 4DODA 2OQEC 4BOKA 1CLCA 4D6IA 3RSYA 2YFOA 3VW5A 3VD9A 1O7DD 2XN0A 1LD8B 3S4CA 1TQUA 3K11A 2WCOA 3D5RA 3N0GA 2FV1A 3IAPA 3SX1A 3X3ZA 1HZFA 4GTPB 3PZ4B 2HTAA 1O6HA 3W5NA 3OS7A 4K3AA 1UMPA 4F13A 1DYUA 4BTXA 1TNOB 2WVXA 3G4FA 1NXCA 2ZISB 3OXUA 2ALWA 1UI8A 3EJPA 5E1QA 4YDEB 4BZEA 1UI7A 2F0YB 3NJVA 2BB5A 1KRFA 1NS7A 3DSXB 3I3EA 4DUXA 4D4BA 4C1SA 1HXCA 5M7YA 5ILKA 1H14A 3EUVB 4GTVB 1NSUA 4D6GA 1LOHA 3DX1A 2PMVA 3Q79B 1PU4A 3VDCA 3M71A 4Q2BA 4DLQA 1N7OA 3SDTA 3X41A 3E37B 1O1TB 1QX1A 4DLOA 3T0BA 1NS0A 1G6IA 1TXKA 2QNOA 5CA3A 1W7CA 3BVXA 1N7QA 2A73B 2Q1FA 3D51A 4L0GA 1W6CA 3MWXA 5KBPA 3HI7A 2EACA 1W6GA 3DX0A 3OBAA 2WDAA 3OB8A 2WOHA 2OKXA 1X9DA 3SFXB 2DRQA 3U7VA 3E80A 1RW9A 4FXKB 4OJZA 1FCEA 3GLYA 5DGRA 1GHQA 4D4DA 1N20A 1WMNA 1H35A 1L1YA 2RI9A 1AGMA 3MI6A 2CG0A 3HXBB 1W5ZA 2WVZA 3ACSA 3LOYA 2F7QA 2P0VA 1N95B 2CWUA 2KXRA 2G0DA 3EJTA 1FP3A 1EKMA 1PX3A 4GTSB 3T09A 3HIGA 1LXMA 1O79A 3H2WA 3VSMA 3BVTA 3M75A 3E6UA 2BRPA 2XQWA 3QR8A 3M7EA 1HXAA 2WW1A 4ZG8A 4FNUA 1W2ZA 3MUY1 1H36A 1V5CA 1NSZA 3T2PA 1LXKA 4D4AA 1FAEA 2WW0A 1IVWA 2E22A 1OACA 3CZJA 3SDQA 2D1WA 2RGKA 3QSPA 2F1AA 3D50A 1QAZA 3E33B 3QXFA 3KIIA 4FNRA 2CFDA 3EU5B 5MEHA 3DSTB 4LNBB 1R34A 2ZBLA 4FNVA 3BUIA 2F1BA 3W7WA 4E1YA 1G87A 3ACTA 3PQIA 4OZVA 4KTPA 5FO7B 1RWAA 1IU7A 1YQ2A 3T2QA 1QBQB 1JCRB 1SQCA 4D1IA 5KKBA 4D6EA 2AHFA 3DSUB 3K25A 2CG1A 4MBGB 1N22A 3WFAA 1L7JA 2GZ6A 1QAKA 4FUSA 2OOVA 1H13A 4Q88A 2JJBA 2ZIRB 3PGBA 3N0FA 1V7WA 1RKYA 4TXTA 2Y73A 4FJQA 4D6JA 1JZ7A 2XHNA 5DGQA 1HMWA 3K7XA 3W7SA 3Q7FB 3S9VA 2Z07A 1SPUA 5IKHA 2WMHA 3WIRA 1H3AA 3PZ2B 3DCDA 1JZ8A 2G02A 3Q75B 5CD2A 3MV11 1GXNA 1KS8A 5ILYA 2CQTA 1OJPA 2H6HB 5IL3A 4ZRQA 4AYRA 2EAEA 3DX4A 3BLCA 1D8EB 1KWFA 3DYOA 4QT9A 4GTQB 1NSVA 1Z45A 5DHKA 1H3CA 2EABA 3QFYA 4ZH5A 4DUWA 3N9HA 3CU7A 1N7NA 2A8ZA 1HXGA 2F7PA 4YCRA 4FNPA 3E1F1 1QWNA 3E73A 3CV5A 2WZSA 4GAXA 3NBBA 3RRSA 2WYNA 3E32B 3GT5A 4EHMB 2WGQA 1H12A 1W6JA 3RENA 4DUVA 1N1ZA 1JYNA 3W7TA 2JKPA 3E30B 4WVAA 3H7LA 3HXEB 1IVVA 3SQCA 4D94A 2JG0A 5EASA 4WU0A 1HCUA 1F4HA 3RX5A 1NS8A 2D8LA 1K72A 3VSNA 2WMKA 1IA7A 1MMZA 3T33A 3F59A 3D4ZA 1DCEB 2XN1A 2WINB 1K1WA 3P5PA 1AVKA 1HXKA 3M72A 1N23A 1N7RA 1VD5A 4D71A 3HIIA 3BGAA 5JMDA 4D72A 2CWVA 3DX3A 2WIIB 1NSSA 3E34B 1MN0A 1JZ2A 1TF4A 2RDYA 1H3BA 1N7PA 3DRAB 2JKAA 3A24A 3BVVA 2ZZRA 3SDUA 3DDFA 3LZ9A 4L9PB 4GTMB 4WVCA 1X81B 3EJRA 3EJQA 4D4CA 2XSGA 1C82A 3AFJA 3NFVA 1L2AA 4ZRPA 4ONTA 4D6FA 5FO9B 3WC3A 4M76A 1SO0A 2V8JA 1J0MA 2DRSA 3ALAA 3EQAA 2V3NA 2AHGA 3T0AA 1JYWA 1EGUA 1TN7B 3M7LA 3TF4A 1G9GA 4GTOB 3D52A 1NL4B 3W7UA 3T0DA 3MUZ1 2BBCA 3DSWB 3CIHA 4DOEA 4D6DA 4GTTB 3Q78B 2C11A 2ZL8A 3DSSB 2CQSA 2OW7A 2DRRA 3M7CA 2OW6A 1W4NA 1UG9A 3H3KA 5GZKA 1N94B 4KTRA 4LNGB 2NVPA 3WA3A 1NC5A 4D1JA 1US1A 2WW2A 1GXOA 5DHIA 1FO2A 1A2VA 3D3IA 1N9AB 3NBJA 2WO0A 1F9GA 2YIKA 3RX8A 3SEPA 3S4DA 1NSMA 1NS2A 4XUVA 1N21A 3DX2A 2J5CA 3M7BA 2XWBB 2CFKA 3A3VA 4BZFA 1QAFA 3VD3A 3QXQA 1X1JA 4BZGA 1F9DA 5A1AA 4LIXA 1OJNA 1G9JA 1KFGA 1D6YA 2CIQA 3BUQA 1PS3A 2V8IA 4KFFA 3OEDA 4YDOB 3ECQA 4L6XA 4KFDA 3NREA 3K5TA 1HN1A 1IA6A 1KSCA 3Q73B 3MPHA 1KREA 5FO8B 1N4PB 3QWTA 1NSRA 3VD5A 5JPMB 4CJ1A 1QSJA 1S64B 1K1XA 5JPNB 4GTRB 1FPPB 4V1SA 2WMJA 3DSVB 3W7XA 1TNZB 1H37A 3T08A 4DI5A 2E24A 2C10A 3WVFA 3RX7A 3VD7A 2CISA 1D6ZA 1R76A 5CZLA 2AFAA 3QDEA 1F4AA 4UFCA 3DYPA 2FUQA 3EU8A 4MU9A 2ZQ0A 2CFWA 3PYAA 3W5MA 4MMHA 4FNSA 4KKJA 3KLSA 1L7KA 4WVBA 4BZHA 2YFNA 3VDAA 3RJ3A 5ILZA 3T2OA 2E2TA 2PNCA 1QALA 3UD2A 2OOVC 3T0UA 2FUTA 2WW3A 1RQ5A 2D5JA 3SDRA 4CJ0A 1LF9A 1N4SB 1TU5A 2F7RA 1NSXA 1F1SA 1IQXA 2WYIA 3X40A 1IQYA 1TN6B 5EAUA 1HTYA 1WU5A 1RWHA 3BLBA 1JYVA 1SIIA 2R2LB 2H6IB 2DROA 5AGDA 1PX4A 2B4FA 3VXDA 1MMXA 4BTYA 3BUPA 2F7OA 5GW7A 3X3YA 1H39A 1XWTA 1O5MB 2X03A 1CB8A 5IKAA 4KKIA 3ANIA 4AYPA 1JZ6A 4D8OA 1RWGA 1V7XA 3BUDA 3DYMA 4NEIA 3QT9A 5ILJA 1KSIA 2I07B 5C05A 1SA5B 1OJMA 2WVXB 1I8QA 1KZPB 2E2UA 1GLMA 4K35A 1OJOA 5ILHA 3KBTC 1SA4B 1WZZA 4AYQA 4GL3A 3A0OA 5M7IA 1GAIA 3KQ4A 1MMYA 3UD1A 1ULVA
chains in the Genus database with same CATH topology
3T2PA 1LXKA 1RWFA 2WW0A 3DECA 3E7JA 4OZWA 2E22A 4J5TA 4F10A 3CZJA 2WVYA 2HTBA 1QAZA 1UG9A 2CIRA 4FNVA 1JYXA 2WW2A 2JKEA 4E1YA 1YQ2A 3J7HA 3T2QA 4OZVA 1JZ5A 1RWAA 2BRVX 2D73A 1HM2A 4D6CA 1J0NA 4D6EA 3NNBA 3K25A 4OK2A 3WFAA 1F9GA 1L7JA 3IMHA 3SEPA 1NSMA 1NS2A 1YGAA 4MMIA 1MMUA 1HM3A 4D6IA 4BZFA 3VD9A 3VD3A 4BZGA 1X1JA 1ULVA 1HV6A 4D6JA 5A1AA 1OJNA 2XHNA 5JMFA 1HMWA 2WCOA 1JZ7A 3IAQA 3IAPA 2CIQA 2WMHA 2HTAA 3DCDA 3OS7A 1JZ8A 4F13A 3ECQA 3MV11 2WVXA 3NREA 1HN1A 2ZXQA 1OJPA 5E1QA 1NSRA 4BZEA 3DYOA 1X1IA 3VD5A 3BLCA 1X1HA 2WMFA 1K1XA 3AFLA 3NJVA 2WMJA 1NS7A 1NKGA 1NSVA 1Z45A 3I3EA 3I3DA 3MV01 4DUXA 4DUWA 4TTGA 3T08A 1N7NA 2E24A 1NS4A 3VD7A 4OK4A 2CISA 3WVFA 1NSUA 4D6HA 3E1F1 3VD4A 1F4AA 4D6GA 1LOHA 2WZSA 3DYPA 2FUQA 2ZQ0A 3VDCA 4DUVA 2WMGA 4AQ0A 3I3BA 3Q1NA 1JYNA 1N7OA 4MMHA 2JKPA 1L7KA 4BZHA 1F4HA 1NS8A 3T0BA 3VDAA 1NS0A 3VSNA 1TXKA 2WMKA 3BS6A 3T2OA 1N7QA 2Q1FA 2WMIB 1JOVA 1MMZA 1JZ4A 2FUTA 1HN0A 3MWXA 2WW3A 3NJXA 1K1WA 1RWCA 1DP0A 3TY1A 1LF9A 3OBAA 2WDAA 1N7RA 3VDBA 4D71A 3OB8A 3BGAA 1NSXA 1F1SA 3E80A 5JMDA 4D72A 1RW9A 4OJZA 4RNLA 1NSSA 1JZ2A 1MN0A 2WMIA 1N7PA 2JKAA 3MUY1 1RWHA 3A24A 1JZ3A 1JYVA 1PX4A 1MMXA 2WVZA 1LF6A 1SNZA 1W3YA 2X03A 1CB8A 2XSGA 1C82A 2BRWA 3NFVA 1JZ6A 1RWGA 3DYMA 1LURA 4NEIA 4D6FA 1SO0A 1J0MA 1PX3A 3T09A 1OJMA 2WVXB 3T0AA 1I8QA 1LXMA 1JYWA 3VSMA 1K1YA 1EGUA 1OJOA 2BRPA 3T0DA 1HMUA 3A0OA 2WW1A 3MUZ1 1MMYA 1NSZA 4D6DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T2P A;  1LXK A;  1RWF A;  2WW0 A;  3DEC A;  3E7J A;  4OZW A;  2E22 A;  4F10 A;  3CZJ A;  2WVY A;  2HTB A;  1QAZ A;  1UG9 A;  2CIR A;  4FNV A;  1JYX A;  2WW2 A;  2JKE A;  4E1Y A;  1YQ2 A;  3J7H A;  3T2Q A;  4OZV A;  1JZ5 A;  1RWA A;  2BRV X;  2D73 A;  1HM2 A;  4D6C A;  1J0N A;  4D6E A;  3NNB A;  3K25 A;  4OK2 A;  3WFA A;  1F9G A;  1L7J A;  3IMH A;  3SEP A;  1NSM A;  1NS2 A;  1YGA A;  4MMI A;  1MMU A;  1HM3 A;  4D6I A;  4BZF A;  3VD9 A;  3VD3 A;  4BZG A;  1X1J A;  1ULV A;  1HV6 A;  4D6J A;  5A1A A;  1OJN A;  2XHN A;  5JMF A;  1HMW A;  2WCO A;  1JZ7 A;  3IAQ A;  3IAP A;  2CIQ A;  2WMH A;  2HTA A;  3DCD A;  3OS7 A;  1JZ8 A;  4F13 A;  3ECQ A;  3MV1 1;  2WVX A;  3NRE A;  1HN1 A;  2ZXQ A;  1OJP A;  5E1Q A;  1NSR A;  4BZE A;  3DYO A;  1X1I A;  3VD5 A;  1X1H A;  2WMF A;  1K1X A;  3AFL A;  3NJV A;  2WMJ A;  1NS7 A;  1NKG A;  1NSV A;  1Z45 A;  3I3E A;  3I3D A;  3MV0 1;  4DUX A;  4DUW A;  4TTG A;  3T08 A;  1N7N A;  2E24 A;  1NS4 A;  3VD7 A;  4OK4 A;  2CIS A;  1NSU A;  4D6H A;  3E1F 1;  3VD4 A;  1F4A A;  4D6G A;  1LOH A;  2WZS A;  3DYP A;  2FUQ A;  2ZQ0 A;  3VDC A;  4DUV A;  2WMG A;  4AQ0 A;  3I3B A;  3Q1N A;  1JYN A;  1N7O A;  4MMH A;  2JKP A;  1L7K A;  4BZH A;  1F4H A;  1NS8 A;  3T0B A;  3VDA A;  1NS0 A;  3VSN A;  1TXK A;  2WMK A;  3T2O A;  1N7Q A;  2Q1F A;  2WMI B;  1JOV A;  1MMZ A;  1JZ4 A;  2FUT A;  1HN0 A;  3MWX A;  2WW3 A;  3NJX A;  1K1W A;  1RWC A;  1DP0 A;  1LF9 A;  3OBA A;  2WDA A;  1N7R A;  3VDB A;  4D71 A;  3OB8 A;  3BGA A;  1NSX A;  1F1S A;  3E80 A;  5JMD A;  4D72 A;  1RW9 A;  4OJZ A;  4RNL A;  1NSS A;  1JZ2 A;  1MN0 A;  2WMI A;  1N7P A;  2JKA A;  3MUY 1;  1RWH A;  3A24 A;  1JZ3 A;  1JYV A;  1PX4 A;  1MMX A;  2WVZ A;  1LF6 A;  1SNZ A;  1W3Y A;  2X03 A;  1CB8 A;  2XSG A;  1C82 A;  2BRW A;  3NFV A;  1JZ6 A;  1RWG A;  3DYM A;  1LUR A;  4NEI A;  4D6F A;  1SO0 A;  1J0M A;  1PX3 A;  3T09 A;  1OJM A;  2WVX B;  3T0A A;  1I8Q A;  1LXM A;  1JYW A;  3VSM A;  1K1Y A;  1EGU A;  1OJO A;  2BRP A;  3T0D A;  1HMU A;  3A0O A;  2WW1 A;  3MUZ 1;  1MMY A;  1NSZ A;  4D6D A; 
#chains in the Genus database with same CATH topology
 3G4D A;  3Q7A B;  3DEC A;  2FV0 A;  2F6D A;  3ANJ A;  1FO3 A;  1O1S B;  3E7J A;  4OZW A;  1AVL A;  4F10 A;  3SXX A;  2WVY A;  1S63 B;  5IL8 A;  1IVU A;  2HTB A;  3SFY B;  4FNQ A;  1TN8 B;  2CIR A;  2CFL A;  2CFG A;  1JYX A;  1RJO A;  3M77 A;  1WMP A;  2WOF A;  2WYH A;  1GA2 A;  1TQV A;  2FUZ A;  1AYX A;  1HM2 A;  3KSQ B;  4D6C A;  2E2V A;  3NNB A;  3DDG A;  1FBO A;  4OK2 A;  3KBU C;  1HX9 A;  1F9O A;  1H54 A;  1WU6 A;  1R33 A;  3AMO B;  1WMO A;  1N24 A;  2V3P A;  4MMI A;  1FMI A;  1TQT A;  1YGA A;  4EV2 A;  2H6G B;  1MMU A;  1HM3 A;  3P2C A;  3PMM A;  4RNQ A;  3WKH A;  1HV6 A;  3BUB A;  2PN5 A;  5JMF A;  2RI8 A;  3IAQ A;  1SIH A;  3M78 A;  3M00 A;  2NOJ A;  3PYB A;  5IK0 A;  4CE7 A;  2GOX A;  1TNU B;  3DPY B;  3AMO A;  2ZXQ A;  3GZK A;  2WY8 A;  3S4B A;  1TQS A;  3BVU A;  3EJS A;  1C3D A;  3HXC B;  1X1I A;  4Z4J A;  4KFE A;  1N1B A;  2H6F B;  1X1H A;  2VN7 A;  2WMF A;  3AFL A;  3EZ8 A;  3KSL B;  1NKG A;  3I3D A;  3MV0 1;  1N4Q B;  2Y74 A;  3CZS A;  3EJU A;  1IS9 A;  4TTG A;  1LTX B;  1NS4 A;  3HXF B;  4OK4 A;  3S4A A;  5ILI A;  5ILD A;  4D6H A;  3VD4 A;  1V7V A;  2IEJ B;  3ON6 A;  4JJJ A;  1N9E A;  2WY7 A;  5IK6 A;  2WMG A;  1HWW A;  2BT3 A;  4AQ0 A;  3I3B A;  3Q1N A;  3PZ1 B;  3PZ3 B;  2KXS A;  3BVW A;  4EV5 A;  3QG0 A;  1JS4 A;  3D5S A;  4Z4L A;  1KSD A;  3BS6 A;  3QRY A;  3WKG A;  2WMI B;  1JOV A;  2SQC A;  2FBA A;  1JZ4 A;  1HN0 A;  1KZO B;  2EAD A;  4TF4 A;  1QWU A;  3NJX A;  3WA2 X;  4V1R A;  2F18 A;  3ANK A;  5IM1 A;  1DOG A;  1RWC A;  1DP0 A;  4FNT A;  1MZC B;  3G6J B;  4LNV A;  3TY1 A;  2BB6 A;  3SDV A;  2BED B;  1JCS B;  3VDB A;  1XWQ A;  1TNB B;  4RNL A;  2WMI A;  5IK9 A;  1FT2 B;  1GXM A;  3X17 A;  1GAH A;  1JZ3 A;  2B39 A;  3M01 A;  1AV4 A;  1QQF A;  2JF4 A;  3SAE A;  3C72 B;  1XW2 A;  1O6R A;  1LF6 A;  1SNZ A;  1D6U A;  5GY3 A;  1GSZ A;  1NI1 B;  1W3Y A;  4EL8 A;  2BRW A;  3HXD B;  1UT9 A;  1LUR A;  1KKT A;  4ZH1 A;  3QFZ A;  3P5R A;  1V5D A;  4FXG B;  3LVT A;  1TQW A;  5E2J A;  1JRQ A;  1K1Y A;  4BOJ A;  1JCQ B;  3QT3 A;  2XFG A;  3QPF A;  1CEM A;  2V8K A;  1LVN A;  1HMU A;  3M74 A;  3X42 A;  2VN4 A;  1O6Q A;  1RWF A;  3M76 A;  4BTW A;  1DL2 A;  2OQE A;  3WUX A;  4J5T A;  2XWJ B;  5EAT A;  3CZN A;  2FYV A;  1WU4 A;  1FBW A;  3WIW A;  3M02 A;  5FOB B;  1TNY B;  3X3X A;  1W6K A;  2JKE A;  3J7H A;  2XN2 A;  1FT1 B;  3KN4 A;  1D8D B;  2CWT A;  1JZ5 A;  3D4Y A;  2BRV X;  3WIQ A;  2D73 A;  2YX9 A;  1J0N A;  1LD7 B;  3WKI A;  1N4R B;  2W0Q A;  2GH4 A;  1O1R B;  3IMH A;  4AYO A;  2ONH A;  1IVX A;  3WKF A;  3M73 A;  2ONG A;  4DOD A;  2OQE C;  4BOK A;  1CLC A;  4D6I A;  3RSY A;  2YFO A;  3VW5 A;  3VD9 A;  1O7D D;  2XN0 A;  1LD8 B;  3S4C A;  1TQU A;  3K11 A;  2WCO A;  3D5R A;  3N0G A;  2FV1 A;  3IAP A;  3SX1 A;  3X3Z A;  1HZF A;  4GTP B;  3PZ4 B;  2HTA A;  1O6H A;  3W5N A;  3OS7 A;  4K3A A;  1UMP A;  4F13 A;  1DYU A;  4BTX A;  1TNO B;  2WVX A;  3G4F A;  1NXC A;  2ZIS B;  3OXU A;  2ALW A;  1UI8 A;  3EJP A;  5E1Q A;  4YDE B;  4BZE A;  1UI7 A;  2F0Y B;  3NJV A;  2BB5 A;  1KRF A;  1NS7 A;  3DSX B;  3I3E A;  4DUX A;  4D4B A;  4C1S A;  1HXC A;  5M7Y A;  5ILK A;  1H14 A;  3EUV B;  4GTV B;  1NSU A;  4D6G A;  1LOH A;  3DX1 A;  2PMV A;  3Q79 B;  1PU4 A;  3VDC A;  3M71 A;  4Q2B A;  4DLQ A;  1N7O A;  3SDT A;  3X41 A;  3E37 B;  1O1T B;  1QX1 A;  4DLO A;  3T0B A;  1NS0 A;  1G6I A;  1TXK A;  2QNO A;  5CA3 A;  1W7C A;  3BVX A;  1N7Q A;  2A73 B;  2Q1F A;  3D51 A;  4L0G A;  1W6C A;  3MWX A;  5KBP A;  3HI7 A;  2EAC A;  1W6G A;  3DX0 A;  3OBA A;  2WDA A;  3OB8 A;  2WOH A;  2OKX A;  1X9D A;  3SFX B;  2DRQ A;  3U7V A;  3E80 A;  1RW9 A;  4FXK B;  4OJZ A;  1FCE A;  3GLY A;  5DGR A;  1GHQ A;  4D4D A;  1N20 A;  1WMN A;  1H35 A;  1L1Y A;  2RI9 A;  1AGM A;  3MI6 A;  2CG0 A;  3HXB B;  1W5Z A;  2WVZ A;  3ACS A;  3LOY A;  2F7Q A;  2P0V A;  1N95 B;  2CWU A;  2KXR A;  2G0D A;  3EJT A;  1FP3 A;  1EKM A;  1PX3 A;  4GTS B;  3T09 A;  3HIG A;  1LXM A;  1O79 A;  3H2W A;  3VSM A;  3BVT A;  3M75 A;  3E6U A;  2BRP A;  2XQW A;  3QR8 A;  3M7E A;  1HXA A;  2WW1 A;  4ZG8 A;  4FNU A;  1W2Z A;  3MUY 1;  1H36 A;  1V5C A;  1NSZ A;  3T2P A;  1LXK A;  4D4A A;  1FAE A;  2WW0 A;  1IVW A;  2E22 A;  1OAC A;  3CZJ A;  3SDQ A;  2D1W A;  2RGK A;  3QSP A;  2F1A A;  3D50 A;  1QAZ A;  3E33 B;  3QXF A;  3KII A;  4FNR A;  2CFD A;  3EU5 B;  5MEH A;  3DST B;  4LNB B;  1R34 A;  2ZBL A;  4FNV A;  3BUI A;  2F1B A;  3W7W A;  4E1Y A;  1G87 A;  3ACT A;  3PQI A;  4OZV A;  4KTP A;  5FO7 B;  1RWA A;  1IU7 A;  1YQ2 A;  3T2Q A;  1QBQ B;  1JCR B;  1SQC A;  4D1I A;  5KKB A;  4D6E A;  2AHF A;  3DSU B;  3K25 A;  2CG1 A;  4MBG B;  1N22 A;  3WFA A;  1L7J A;  2GZ6 A;  1QAK A;  4FUS A;  2OOV A;  1H13 A;  4Q88 A;  2JJB A;  2ZIR B;  3PGB A;  3N0F A;  1V7W A;  1RKY A;  4TXT A;  2Y73 A;  4FJQ A;  4D6J A;  1JZ7 A;  2XHN A;  5DGQ A;  1HMW A;  3K7X A;  3W7S A;  3Q7F B;  3S9V A;  2Z07 A;  1SPU A;  5IKH A;  2WMH A;  3WIR A;  1H3A A;  3PZ2 B;  3DCD A;  1JZ8 A;  2G02 A;  3Q75 B;  5CD2 A;  3MV1 1;  1GXN A;  1KS8 A;  5ILY A;  2CQT A;  1OJP A;  2H6H B;  5IL3 A;  4ZRQ A;  4AYR A;  2EAE A;  3DX4 A;  3BLC A;  1D8E B;  1KWF A;  3DYO A;  4QT9 A;  4GTQ B;  1NSV A;  1Z45 A;  5DHK A;  1H3C A;  2EAB A;  3QFY A;  4ZH5 A;  4DUW A;  3N9H A;  3CU7 A;  1N7N A;  2A8Z A;  1HXG A;  2F7P A;  4YCR A;  4FNP A;  3E1F 1;  1QWN A;  3E73 A;  3CV5 A;  2WZS A;  4GAX A;  3NBB A;  3RRS A;  2WYN A;  3E32 B;  3GT5 A;  4EHM B;  2WGQ A;  1H12 A;  1W6J A;  3REN A;  4DUV A;  1N1Z A;  1JYN A;  3W7T A;  2JKP A;  3E30 B;  4WVA A;  3H7L A;  3HXE B;  1IVV A;  3SQC A;  4D94 A;  2JG0 A;  5EAS A;  4WU0 A;  1HCU A;  1F4H A;  3RX5 A;  1NS8 A;  2D8L A;  1K72 A;  3VSN A;  2WMK A;  1IA7 A;  1MMZ A;  3T33 A;  3F59 A;  3D4Z A;  1DCE B;  2XN1 A;  2WIN B;  1K1W A;  3P5P A;  1AVK A;  1HXK A;  3M72 A;  1N23 A;  1N7R A;  1VD5 A;  4D71 A;  3HII A;  3BGA A;  5JMD A;  4D72 A;  2CWV A;  3DX3 A;  2WII B;  1NSS A;  3E34 B;  1MN0 A;  1JZ2 A;  1TF4 A;  2RDY A;  1H3B A;  1N7P A;  3DRA B;  2JKA A;  3A24 A;  3BVV A;  2ZZR A;  3SDU A;  3DDF A;  3LZ9 A;  4L9P B;  4GTM B;  4WVC A;  1X81 B;  3EJR A;  3EJQ A;  4D4C A;  2XSG A;  1C82 A;  3AFJ A;  3NFV A;  1L2A A;  4ZRP A;  4ONT A;  4D6F A;  5FO9 B;  3WC3 A;  4M76 A;  1SO0 A;  2V8J A;  1J0M A;  2DRS A;  3ALA A;  3EQA A;  2V3N A;  2AHG A;  3T0A A;  1JYW A;  1EGU A;  1TN7 B;  3M7L A;  3TF4 A;  1G9G A;  4GTO B;  3D52 A;  1NL4 B;  3W7U A;  3T0D A;  3MUZ 1;  2BBC A;  3DSW B;  3CIH A;  4DOE A;  4D6D A;  4GTT B;  3Q78 B;  2C11 A;  2ZL8 A;  3DSS B;  2CQS A;  2OW7 A;  2DRR A;  3M7C A;  2OW6 A;  1W4N A;  1UG9 A;  3H3K A;  5GZK A;  1N94 B;  4KTR A;  4LNG B;  2NVP A;  3WA3 A;  1NC5 A;  4D1J A;  1US1 A;  2WW2 A;  1GXO A;  5DHI A;  1FO2 A;  1A2V A;  3D3I A;  1N9A B;  3NBJ A;  2WO0 A;  1F9G A;  2YIK A;  3RX8 A;  3SEP A;  3S4D A;  1NSM A;  1NS2 A;  4XUV A;  1N21 A;  3DX2 A;  2J5C A;  3M7B A;  2XWB B;  2CFK A;  3A3V A;  4BZF A;  1QAF A;  3VD3 A;  3QXQ A;  1X1J A;  4BZG A;  1F9D A;  5A1A A;  4LIX A;  1OJN A;  1G9J A;  1KFG A;  1D6Y A;  2CIQ A;  3BUQ A;  1PS3 A;  2V8I A;  4KFF A;  3OED A;  4YDO B;  3ECQ A;  4L6X A;  4KFD A;  3NRE A;  3K5T A;  1HN1 A;  1IA6 A;  1KSC A;  3Q73 B;  3MPH A;  1KRE A;  5FO8 B;  1N4P B;  3QWT A;  1NSR A;  3VD5 A;  5JPM B;  4CJ1 A;  1QSJ A;  1S64 B;  1K1X A;  5JPN B;  4GTR B;  1FPP B;  4V1S A;  2WMJ A;  3DSV B;  3W7X A;  1TNZ B;  1H37 A;  3T08 A;  4DI5 A;  2E24 A;  2C10 A;  3WVF A;  3RX7 A;  3VD7 A;  2CIS A;  1D6Z A;  1R76 A;  5CZL A;  2AFA A;  3QDE A;  1F4A A;  4UFC A;  3DYP A;  2FUQ A;  3EU8 A;  4MU9 A;  2ZQ0 A;  2CFW A;  3PYA A;  3W5M A;  4MMH A;  4FNS A;  4KKJ A;  3KLS A;  1L7K A;  4WVB A;  4BZH A;  2YFN A;  3VDA A;  3RJ3 A;  5ILZ A;  3T2O A;  2E2T A;  2PNC A;  1QAL A;  3UD2 A;  2OOV C;  3T0U A;  2FUT A;  2WW3 A;  1RQ5 A;  2D5J A;  3SDR A;  4CJ0 A;  1LF9 A;  1N4S B;  1TU5 A;  2F7R A;  1NSX A;  1F1S A;  1IQX A;  2WYI A;  3X40 A;  1IQY A;  1TN6 B;  5EAU A;  1HTY A;  1WU5 A;  1RWH A;  3BLB A;  1JYV A;  1SII A;  2R2L B;  2H6I B;  2DRO A;  5AGD A;  1PX4 A;  2B4F A;  3VXD A;  1MMX A;  4BTY A;  3BUP A;  2F7O A;  5GW7 A;  3X3Y A;  1H39 A;  1XWT A;  1O5M B;  2X03 A;  1CB8 A;  5IKA A;  4KKI A;  3ANI A;  4AYP A;  1JZ6 A;  4D8O A;  1RWG A;  1V7X A;  3BUD A;  3DYM A;  4NEI A;  3QT9 A;  5ILJ A;  1KSI A;  2I07 B;  5C05 A;  1SA5 B;  1OJM A;  2WVX B;  1I8Q A;  1KZP B;  2E2U A;  1GLM A;  4K35 A;  1OJO A;  5ILH A;  3KBT C;  1SA4 B;  1WZZ A;  4AYQ A;  4GL3 A;  3A0O A;  5M7I A;  1GAI A;  3KQ4 A;  1MMY A;  3UD1 A;  1ULV A; 
#chains in the Genus database with same CATH homology
 3T2P A;  1LXK A;  1RWF A;  2WW0 A;  3DEC A;  3E7J A;  4OZW A;  2E22 A;  4J5T A;  4F10 A;  3CZJ A;  2WVY A;  2HTB A;  1QAZ A;  1UG9 A;  2CIR A;  4FNV A;  1JYX A;  2WW2 A;  2JKE A;  4E1Y A;  1YQ2 A;  3J7H A;  3T2Q A;  4OZV A;  1JZ5 A;  1RWA A;  2BRV X;  2D73 A;  1HM2 A;  4D6C A;  1J0N A;  4D6E A;  3NNB A;  3K25 A;  4OK2 A;  3WFA A;  1F9G A;  1L7J A;  3IMH A;  3SEP A;  1NSM A;  1NS2 A;  1YGA A;  4MMI A;  1MMU A;  1HM3 A;  4D6I A;  4BZF A;  3VD9 A;  3VD3 A;  4BZG A;  1X1J A;  1ULV A;  1HV6 A;  4D6J A;  5A1A A;  1OJN A;  2XHN A;  5JMF A;  1HMW A;  2WCO A;  1JZ7 A;  3IAQ A;  3IAP A;  2CIQ A;  2WMH A;  2HTA A;  3DCD A;  3OS7 A;  1JZ8 A;  4F13 A;  3ECQ A;  3MV1 1;  2WVX A;  3NRE A;  1HN1 A;  2ZXQ A;  1OJP A;  5E1Q A;  1NSR A;  4BZE A;  3DYO A;  1X1I A;  3VD5 A;  3BLC A;  1X1H A;  2WMF A;  1K1X A;  3AFL A;  3NJV A;  2WMJ A;  1NS7 A;  1NKG A;  1NSV A;  1Z45 A;  3I3E A;  3I3D A;  3MV0 1;  4DUX A;  4DUW A;  4TTG A;  3T08 A;  1N7N A;  2E24 A;  1NS4 A;  3VD7 A;  4OK4 A;  2CIS A;  3WVF A;  1NSU A;  4D6H A;  3E1F 1;  3VD4 A;  1F4A A;  4D6G A;  1LOH A;  2WZS A;  3DYP A;  2FUQ A;  2ZQ0 A;  3VDC A;  4DUV A;  2WMG A;  4AQ0 A;  3I3B A;  3Q1N A;  1JYN A;  1N7O A;  4MMH A;  2JKP A;  1L7K A;  4BZH A;  1F4H A;  1NS8 A;  3T0B A;  3VDA A;  1NS0 A;  3VSN A;  1TXK A;  2WMK A;  3BS6 A;  3T2O A;  1N7Q A;  2Q1F A;  2WMI B;  1JOV A;  1MMZ A;  1JZ4 A;  2FUT A;  1HN0 A;  3MWX A;  2WW3 A;  3NJX A;  1K1W A;  1RWC A;  1DP0 A;  3TY1 A;  1LF9 A;  3OBA A;  2WDA A;  1N7R A;  3VDB A;  4D71 A;  3OB8 A;  3BGA A;  1NSX A;  1F1S A;  3E80 A;  5JMD A;  4D72 A;  1RW9 A;  4OJZ A;  4RNL A;  1NSS A;  1JZ2 A;  1MN0 A;  2WMI A;  1N7P A;  2JKA A;  3MUY 1;  1RWH A;  3A24 A;  1JZ3 A;  1JYV A;  1PX4 A;  1MMX A;  2WVZ A;  1LF6 A;  1SNZ A;  1W3Y A;  2X03 A;  1CB8 A;  2XSG A;  1C82 A;  2BRW A;  3NFV A;  1JZ6 A;  1RWG A;  3DYM A;  1LUR A;  4NEI A;  4D6F A;  1SO0 A;  1J0M A;  1PX3 A;  3T09 A;  1OJM A;  2WVX B;  3T0A A;  1I8Q A;  1LXM A;  1JYW A;  3VSM A;  1K1Y A;  1EGU A;  1OJO A;  2BRP A;  3T0D A;  1HMU A;  3A0O A;  2WW1 A;  3MUZ 1;  1MMY A;  1NSZ A;  4D6D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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