1HMUA

Active site of chondroitinase ac lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis
Total Genus 244
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
244
sequence length
674
structure length
674
Chain Sequence
b'GTAELIMKRVMLDLKKPLRNMDKVAEKNLNTLQPDGSWKDVPYKDDAMTNWLPNNHLLQLETIIQAYIEKDSHYYGDDKVFDQISKAFKYWYDSDPKSRNWWHNEIATPQALGEMLILMRYGKKPLDEALVHKLTERMKRGEPEKKTGANKTDIALHYFYRALLTSDEALLSFAVKELFYPVQFVHYEEGLQYDYSYLQHGPQLQISSYGAVFITGVLKLANYVRDTPYALSTEKLAIFSKYYRDSYLKAIRGSYMDFNVEGRGVSRPDILNKKAEKKRLLVAKMIDLKHTEEWADAIARTDSTVAAGYKIEPYHHQFWNGDYVQHLRPAYSFNVRMVSKRTRRSESGNKENLLGRYLSDGATNIQLRGPEYYNIMPVWEWDKIPGITSRDYLTDRPLTKLWGEQGSNDFAGGVSDGVYGASAYALDYDSLQAKKAWFFFDKEIVCLGAGINSNAPENITTTLNQSWLNGPVISTAGKTGRGKITTFKAQGQFWLLHDAIGYYFPEGANLSLSTQSQKGNWFHINNSHSKDEVSGDVFKLWINHGARPENAQYAYIVLPGINKPEEIKKYNGTAPKVLANTNQLQAVYHQQLDMVQAIFYTAGKLSVAGIEIETDKPCAVLIKHINGKQVIWAADPLQKEKTAVLSIRDLKTGKTNRVKIDFPQQEFAGATVEL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords CHONDROITINASE AC
publication title Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis.
pubmed doi rcsb
source organism Pedobacter heparinus
molecule tags Lyase
total genus 244
structure length 674
sequence length 674
ec nomenclature ec 4.2.2.5: Chondroitin AC lyase.
pdb deposition date 2000-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1hmuA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1hmuA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1hmuA02
3A24A 3IAQA 3NJVA 1NS0A 2WZSA 3T0AA 4MMIA 4E1YA 1TXKA 3NJXA 2ZQ0A 1W3YA 3E7JA 3ECQA 3MUZ1 4BZHA 5E1QA 2HTAA 3E80A 1LF9A 1RWAA 3I3BA 1N7NA 1JYXA 2WW1A 2WW0A 3OS7A 1SNZA 2CIQA 1JZ2A 1RWCA 1JZ3A 2XHNA 1OJMA 2WMGA 2BRWA 1RWHA 1C82A 1J0NA 1MN0A 1DP0A 1HM2A 4D6FA 3T0DA 1NSSA 3MV01 3VD5A 5A1AA 2WVXB 3J7HA 3IMHA 2FUQA 4D6IA 2WMJA 4F13A 3T2QA 3VD4A 4D6DA 4D71A 1OJOA 2WVYA 4DUXA 4FNVA 1NS7A 1OJPA 1HMWA 4OK4A 1N7PA 1PX4A 3OB8A 1MMYA 3DYOA 4TTGA 3VSMA 1MMZA 1N7QA 1LOHA 4DUVA 3CZJA 3VSNA 2WVZA 2WW2A 1L7JA 2BRPA 1SO0A 1QAZA 2WDAA 2WMIB 1NS8A 2WMHA 2FUTA 3WFAA 2E24A 1JZ8A 1MMUA 1X1IA 4D6GA 1F4AA 3Q1NA 2WMKA 2WCOA 1K1WA 1NSMA 1N7OA 2JKEA 1NSZA 2XSGA 1JYVA 1F1SA 1JOVA 3BGAA 3NNBA 1NS4A 1JYNA 1HN0A 2JKAA 1YGAA 1X1HA 5JMDA 1Z45A 1NSVA 3I3DA 1JZ7A 1RWFA 2D73A 4OZVA 1YQ2A 4AQ0A 3MV11 4MMHA 4OJZA 4D6HA 3IAPA 3T0BA 4BZFA 1I8QA 2BRVX 1LF6A 1LURA 3AFLA 3DECA 1ULVA 3VD9A 1L7KA 1F4HA 3VDAA 1N7RA 2WVXA 3T08A 3MUY1 1LXMA 3DYPA 3SEPA 4NEIA 1EGUA 2CIRA 3DYMA 3I3EA 1UG9A 3NFVA 1LXKA 1HMUA 1J0MA 5JMFA 2HTBA 2Q1FA 4D6CA 1MMXA 1CB8A 3T09A 1JZ4A 3OBAA 3VDBA 2WMIA 4F10A 1X1JA 1RW9A 1NKGA 1F9GA 3A0OA 3DCDA 1JYWA 2ZXQA 3T2OA 3E1F1 4D6JA 2JKPA 4D72A 4BZEA 3VD7A 4OK2A 1HN1A 1NSRA 1JZ5A 2X03A 1JZ6A 3K25A 2CISA 3NREA 2WW3A 4RNLA 1NS2A 3T2PA 2E22A 1K1XA 1RWGA 1OJNA 1HM3A 4BZGA 3VDCA 1K1YA 3MWXA 1NSXA 4DUWA 1HV6A 1NSUA 4OZWA 3VD3A 1PX3A 2WMFA 4D6EA
chains in the Genus database with same CATH superfamily
2W0QA 1TQVA 3SAEA 1GA2A 2G02A 3HIIA 4LNVA 5CD2A 3RX8A 2ZQ0A 1H37A 1W3YA 1TN8B 3E7JA 4KFDA 3MUZ1 5EASA 2F7PA 1TNOB 2HTAA 3E80A 4D4BA 1LVNA 2CWVA 4FNSA 1GLMA 4AYQA 2GH4A 3DDFA 3I3BA 1RJOA 1N7NA 4KTPA 2AFAA 3ANKA 3N0GA 1KKTA 3PZ2B 1IQXA 1LD8B 3BUIA 4FXKB 1HM2A 1FT2B 1HXCA 2R2LB 3DSUB 1H3AA 4D6FA 1NSSA 3T0DA 3QG0A 3J7HA 1WMPA 2OOVA 1QQFA 3VD4A 4GTTB 1LTXB 1HCUA 5CZLA 4FNVA 3G6JB 1OJPA 1HMWA 2A8ZA 1N7PA 3A3VA 4OK4A 3S4AA 3W7WA 1PX4A 3VSMA 1MMZA 4FNRA 1WZZA 4WVCA 2QNOA 3WVFA 2FV0A 5JPNB 3H7LA 3M74A 1SO0A 2BRPA 2WVZA 3MPHA 2WDAA 5M7YA 2WMIB 2WMHA 1X9DA 1SA4B 2FUTA 1D6YA 1IQYA 2OQEA 1NSMA 2XSGA 3RJ3A 5IL3A 4KKJA 5ILDA 3M73A 1GAHA 1SQCA 2WYNA 4GTVB 3BS6A 3DX4A 3PZ3B 1O7DD 2FBAA 4Z4LA 4BTYA 1FCEA 1NSVA 4D1JA 1JZ7A 1W2ZA 1TN7B 1LD7B 3MV11 2V8IA 3T0BA 2BRVX 1LF6A 1O6RA 2P0VA 3M00A 3WKFA 1F9DA 1ULVA 1AVLA 3EJPA 1L7KA 3P5PA 3T08A 4QT9A 2V8KA 1W4NA 3F59A 4AYOA 3TF4A 4NEIA 2H6FB 4EV5A 3AMOA 1N4PB 3I3EA 3KSLB 3QPFA 1HMUA 2AHGA 2EACA 2ONHA 1MMXA 3EU8A 3CZNA 3D3IA 3DSWB 1JZ4A 3OBAA 1QAKA 3VDBA 5IK0A 2WMIA 1CEMA 2CQSA 2GOXA 1W7CA 3RENA 1JYWA 1FMIA 2D5JA 2V8JA 3MI6A 4Q88A 2E2TA 2WOHA 1IVUA 4D6JA 4BZEA 2Z07A 4DLOA 3KN4A 3VD7A 1W6KA 4OK2A 1H3BA 1O1SB 1SA5B 1NSRA 3X41A 2C10A 3GT5A 4ZG8A 4KFEA 1V7XA 3UD2A 1SIIA 5ILZA 3BUBA 3PYBA 1HM3A 3Q7AB 2CFWA 3KQ4A 1KWFA 1K1YA 4D4DA 1HV6A 5ILJA 2JJBA 4OZWA 1HTYA 3H3KA 3QSPA 3QRYA 1F9OA 3NJVA 4KFFA 2DRSA 2KXSA 2WZSA 4E1YA 3SDTA 1OACA 1TU5A 4TXTA 3W7TA 3ECQA 3ACSA 1H36A 5KBPA 4YCRA 4BZHA 3QFYA 1IU7A 1TQSA 1LF9A 2BEDB 4GL3A 5IKHA 1RWAA 4Z4JA 4BOKA 3Q73B 1N23A 1GSZA 3ANIA 2WW1A 3OS7A 2WINB 5JPMB 2PMVA 2CIQA 4J5TA 1JZ2A 1D6ZA 3X3YA 1HZFA 2BB6A 1G87A 2BRWA 1C82A 1J0NA 3D50A 3QT9A 3BUDA 4WVBA 3G4DA 1RQ5A 3KLSA 1HX9A 1KZOB 2WMJA 2XQWA 3DDGA 3T0UA 3T33A 3T2QA 2EAEA 5GY3A 2WVYA 3M7LA 2NOJA 1UI8A 5DGRA 3PZ4B 4GTMB 1GXMA 1N4RB 1N7QA 1S63B 3Q78B 4DUVA 1GHQA 2ZIRB 3E33B 3SDQA 3KBUC 3SFXB 3BVUA 1WU4A 1N94B 3SXXA 1MMUA 1N24A 3QFZA 1AV4A 3Q1NA 3WA3A 1L1YA 2WMKA 5EAUA 4TTGA 3M76A 3AFJA 3VW5A 1K1WA 2PNCA 1N21A 3CU7A 3E34B 2OW7A 2DRQA 4WU0A 1DCEB 2ZZRA 3S4BA 1WMOA 4GTOB 1HN0A 2G0DA 1QWUA 2FYVA 3Q7FB 1R76A 3I3DA 2OW6A 3BLBA 1G6IA 4ONTA 1FPPB 5FOBB 3AMOB 2E2UA 3NBBA 4D6HA 1HXGA 4XUVA 4BZFA 3HXEB 4FUSA 4BOJA 3WKHA 1KZPB 1JCSB 1N4SB 1H12A 1FO2A 1W6CA 3DECA 4FNTA 1H39A 3DX2A 3VD9A 3KSQB 3CV5A 3VDAA 5FO9B 3K7XA 3BLCA 1N7RA 2E2VA 3E6UA 2YIKA 1EGUA 3M01A 3DYMA 3M7CA 1TNUB 3D5SA 1RKYA 2ONGA 3EJSA 4ZRQA 1J0MA 5JMFA 1SPUA 2V3NA 2F7OA 4Q2BA 4V1SA 4ZH1A 3E30B 3KIIA 3W7SA 1V5DA 4LNGB 1TQUA 3T2OA 1UI7A 2OKXA 1QX1A 4D72A 4GAXA 3X3XA 3P2CA 1JZ5A 2X03A 3D51A 3M71A 1JZ6A 3K25A 1H35A 3D4YA 1O1TB 4FNPA 2E22A 4GTRB 4RNQA 1RWGA 1OJNA 3Q79B 2OOVC 3QWTA 3DSVB 3G4FA 4BZGA 2H6HB 2F1BA 3VD3A 4CJ0A 2RI8A 2EABA 1NXCA 1RWCA 1HXAA 2A73B 1GXOA 3S4DA 3W5MA 3A24A 2H6GB 3NBJA 3LVTA 3WUXA 4JJJA 1QSJA 1D6UA 1IVVA 3M7BA 5EATA 2JG0A 1N4QB 1R34A 1XW2A 2GZ6A 4D4AA 1SIHA 1H3CA 1IA6A 2OQEC 4FXGB 3QXFA 4CJ1A 1JRQA 1H54A 4TF4A 1NC5A 3PYAA 3VXDA 1R33A 1FP3A 3ACTA 2WW0A 1UMPA 2RGKA 1XWTA 1JCQB 4KTRA 4V1RA 4L9PB 1SNZA 1JZ3A 2XHNA 1JS4A 5DHIA 4DI5A 3TY1A 3K5TA 3LOYA 1RWHA 1MN0A 1D8DB 2B39A 1DP0A 1O5MB 3EZ8A 1O6HA 3GLYA 3MV01 3VD5A 1X81B 2Y73A 3GZKA 3IMHA 2F0YB 4AYPA 2ALWA 2F18A 4D71A 4YDEB 3BVVA 3E32B 3QT3A 1LOHA 4D1IA 1W6JA 3CZJA 5DHKA 3WC3A 1L7JA 1CLCA 1QAZA 2RDYA 2BBCA 1H13A 4BTXA 5AGDA 4YDOB 2E24A 1JZ8A 1O79A 4D6GA 1F4AA 2Y74A 4FJQA 1N7OA 1W6GA 2CFLA 2JKEA 1JYVA 1F1SA 1AYXA 2BB5A 5MEHA 3C72B 2WO0A 2YFOA 3SDUA 3QR8A 3CIHA 2H6IB 1KSIA 3E73A 1NS4A 2CG0A 3BVWA 3DX3A 3HXFB 1JYNA 2C11A 2JKAA 1V7VA 1N1BA 3EJRA 1TF4A 5CA3A 5JMDA 4D8OA 3ON6A 2D1WA 1IA7A 1RWFA 2F7QA 1UT9A 2AHFA 3EU5B 2CWTA 2WY7A 5FO7B 1YQ2A 1FT1B 3HXDB 4MMHA 5IL8A 4DLQA 1I8QA 3HIGA 3SQCA 3WKIA 3KBTC 1LURA 4BTWA 2XN2A 4UFCA 1F4HA 1KS8A 4MBGB 1H14A 5ILIA 2CIRA 3BUPA 3EJQA 5ILYA 1UG9A 3D4ZA 2WIIB 3ANJA 4KKIA 4MU9A 4GTQB 2Q1FA 2IEJB 3W7UA 2DRRA 4EHMB 2XFGA 1X1JA 4F10A 1W5ZA 2PN5A 1RW9A 1NKGA 1F9GA 3DCDA 3W5NA 1V5CA 2RI9A 2ZXQA 3PMMA 2XWBB 1N20A 2VN7A 3RX5A 3H2WA 1O1RB 2CQTA 1FO3A 2WOFA 3D5RA 1O6QA 5FO8B 1QBQB 3SX1A 1KFGA 2XN0A 3DRAB 4GTPB 1MZCB 3EQAA 1NS2A 1TQWA 3T2PA 1QALA 3LZ9A 1K1XA 1WU5A 1FBWA 1C3DA 2CFKA 3DX1A 3X40A 3VDCA 5ILHA 1NSXA 3ALAA 2B4FA 2CWUA 3BVTA 5IM1A 1S64B 3HXCB 3DSTB 5GZKA 1PX3A 4GTSB 2WMFA 1N9EA 1FAEA 2JF4A 3DPYB 3M72A 2YFNA 1NS0A 3IAQA 3T0AA 4MMIA 1IVWA 1TXKA 3NJXA 2XN1A 2J5CA 1G9GA 5E1QA 2SQCA 1NL4B 1TNBB 3BUQA 2D8LA 1PU4A 1DOGA 3S4CA 5M7IA 1JYXA 1HXKA 2EADA 3S9VA 2WYHA 3RRSA 2WYIA 3E37B 5IK9A 4FNUA 1JCRB 1AGMA 5IK6A 4ZH5A 4K3AA 1TN6B 2NVPA 1OJMA 2WMGA 4D4CA 4D94A 3X3ZA 3UD1A 4EV2A 3QXQA 1K72A 5DGQA 5A1AA 2WVXB 2FUQA 3M77A 1VD5A 3WIWA 3M7EA 4F13A 4D6IA 1US1A 3M75A 4D6DA 3QDEA 4DUXA 1OJOA 2CFGA 2WY8A 2ZBLA 1NS7A 3OB8A 1MMYA 1PS3A 3DYOA 4L0GA 3WIQA 3RSYA 1TNZB 3WKGA 3VSNA 2WW2A 4EL8A 4LNBB 3EJUA 1NS8A 3WFAA 3PQIA 2VN4A 4WVAA 1X1IA 1N1ZA 4DODA 4CE7A 1DL2A 1IVXA 2CG1A 2WCOA 3EUVB 1NSZA 3BGAA 1JOVA 4AYRA 1FBOA 3M78A 3NNBA 2WGQA 3D52A 3M02A 1DYUA 3SDRA 3EJTA 1YGAA 1X1HA 3P5RA 1Z45A 2D73A 4OZVA 1V7WA 1KSDA 3DX0A 4AQ0A 4OJZA 3IAPA 3OXUA 3PGBA 2F6DA 1A2VA 2BT3A 3AFLA 3BVXA 3HI7A 3X42A 2F7RA 3SDVA 5ILKA 1D8EB 5C05A 1GAIA 4LIXA 3Q75B 1KRFA 3CZSA 2WVXA 4K35A 3MUY1 1LXMA 5GW7A 3PZ1B 5IKAA 3DYPA 3N9HA 3SEPA 1WU6A 1N22A 1XWQA 3DSSB 1TNYB 1L2AA 3NFVA 1LXKA 4L6XA 1N9AB 4DOEA 2HTBA 4D6CA 1CB8A 3T09A 2KXRA 5KKBA 1G9JA 2V3PA 1AVKA 3K11A 2F1AA 3HXBB 3A0OA 3RX7A 1IS9A 1TQTA 3E1F1 2JKPA 3W7XA 1HN1A 1N95B 2DROA 2CFDA 3X17A 3WA2X 4ZRPA 2FUZA 2XWJB 2CISA 3SFYB 3WIRA 3DSXB 3NREA 1EKMA 2WW3A 2YX9A 3N0FA 4RNLA 1KSCA 2ZISB 1WMNA 1NI1B 1QAFA 3U7VA 1KREA 3OEDA 1GXNA 1QWNA 2FV1A 3MWXA 2ZL8A 1HWWA 4FNQA 4DUWA 4C1SA 1NSUA 5E2JA 4M76A 2I07B 4D6EA
chains in the Genus database with same CATH topology
3A24A 3IAQA 3NJVA 1NS0A 2WZSA 3T0AA 4MMIA 4E1YA 1TXKA 3NJXA 2ZQ0A 1W3YA 3E7JA 3ECQA 3MUZ1 4BZHA 5E1QA 2HTAA 3E80A 1LF9A 1RWAA 3I3BA 1N7NA 1JYXA 2WW1A 2WW0A 3OS7A 1SNZA 2CIQA 4J5TA 1JZ2A 1RWCA 1JZ3A 2XHNA 1OJMA 3TY1A 2WMGA 2BRWA 1RWHA 1C82A 1J0NA 1MN0A 1DP0A 1HM2A 4D6FA 3T0DA 1NSSA 3MV01 3VD5A 5A1AA 2WVXB 3J7HA 3IMHA 2FUQA 4D6IA 2WMJA 4F13A 3T2QA 3VD4A 4D6DA 4D71A 1OJOA 2WVYA 4DUXA 4FNVA 1NS7A 1OJPA 1HMWA 4OK4A 1N7PA 1PX4A 3OB8A 1MMYA 3DYOA 4TTGA 3VSMA 1MMZA 1N7QA 1LOHA 4DUVA 3CZJA 3WVFA 3VSNA 2WVZA 2WW2A 1L7JA 2BRPA 1SO0A 1QAZA 2WDAA 2WMIB 1NS8A 2WMHA 2FUTA 3WFAA 2E24A 1JZ8A 1MMUA 1X1IA 4D6GA 1F4AA 3Q1NA 2WMKA 2WCOA 1K1WA 1NSMA 1N7OA 2JKEA 1NSZA 2XSGA 1JYVA 1F1SA 1JOVA 3BGAA 3NNBA 1NS4A 3BS6A 1JYNA 1HN0A 2JKAA 1YGAA 1X1HA 5JMDA 1Z45A 1NSVA 3I3DA 1JZ7A 1RWFA 2D73A 4OZVA 1YQ2A 4AQ0A 3MV11 4MMHA 4OJZA 4D6HA 3IAPA 3T0BA 4BZFA 1I8QA 2BRVX 1LF6A 1LURA 3AFLA 3DECA 1ULVA 3VD9A 1L7KA 1F4HA 3VDAA 3BLCA 1N7RA 2WVXA 3T08A 3MUY1 1LXMA 3DYPA 3SEPA 4NEIA 1EGUA 2CIRA 3DYMA 3I3EA 1UG9A 3NFVA 1LXKA 1HMUA 1J0MA 5JMFA 2HTBA 2Q1FA 4D6CA 1MMXA 1CB8A 3T09A 1JZ4A 3OBAA 3VDBA 2WMIA 4F10A 1X1JA 1RW9A 1NKGA 1F9GA 3A0OA 3DCDA 1JYWA 2ZXQA 3T2OA 3E1F1 4D6JA 2JKPA 4D72A 4BZEA 3VD7A 4OK2A 1HN1A 1NSRA 1JZ5A 2X03A 1JZ6A 3K25A 2CISA 3NREA 2WW3A 4RNLA 1NS2A 3T2PA 2E22A 1K1XA 1RWGA 1OJNA 1HM3A 4BZGA 3VDCA 1K1YA 3MWXA 1NSXA 4DUWA 1HV6A 1NSUA 4OZWA 3VD3A 1PX3A 2WMFA 4D6EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3A24 A;  3IAQ A;  3NJV A;  1NS0 A;  2WZS A;  3T0A A;  4MMI A;  4E1Y A;  1TXK A;  3NJX A;  2ZQ0 A;  1W3Y A;  3E7J A;  3ECQ A;  3MUZ 1;  4BZH A;  5E1Q A;  2HTA A;  3E80 A;  1LF9 A;  1RWA A;  3I3B A;  1N7N A;  1JYX A;  2WW1 A;  2WW0 A;  3OS7 A;  1SNZ A;  2CIQ A;  1JZ2 A;  1RWC A;  1JZ3 A;  2XHN A;  1OJM A;  2WMG A;  2BRW A;  1RWH A;  1C82 A;  1J0N A;  1MN0 A;  1DP0 A;  1HM2 A;  4D6F A;  3T0D A;  1NSS A;  3MV0 1;  3VD5 A;  5A1A A;  2WVX B;  3J7H A;  3IMH A;  2FUQ A;  4D6I A;  2WMJ A;  4F13 A;  3T2Q A;  3VD4 A;  4D6D A;  4D71 A;  1OJO A;  2WVY A;  4DUX A;  4FNV A;  1NS7 A;  1OJP A;  1HMW A;  4OK4 A;  1N7P A;  1PX4 A;  3OB8 A;  1MMY A;  3DYO A;  4TTG A;  3VSM A;  1MMZ A;  1N7Q A;  1LOH A;  4DUV A;  3CZJ A;  3VSN A;  2WVZ A;  2WW2 A;  1L7J A;  2BRP A;  1SO0 A;  1QAZ A;  2WDA A;  2WMI B;  1NS8 A;  2WMH A;  2FUT A;  3WFA A;  2E24 A;  1JZ8 A;  1MMU A;  1X1I A;  4D6G A;  1F4A A;  3Q1N A;  2WMK A;  2WCO A;  1K1W A;  1NSM A;  1N7O A;  2JKE A;  1NSZ A;  2XSG A;  1JYV A;  1F1S A;  1JOV A;  3BGA A;  3NNB A;  1NS4 A;  1JYN A;  1HN0 A;  2JKA A;  1YGA A;  1X1H A;  5JMD A;  1Z45 A;  1NSV A;  3I3D A;  1JZ7 A;  1RWF A;  2D73 A;  4OZV A;  1YQ2 A;  4AQ0 A;  3MV1 1;  4MMH A;  4OJZ A;  4D6H A;  3IAP A;  3T0B A;  4BZF A;  1I8Q A;  2BRV X;  1LF6 A;  1LUR A;  3AFL A;  3DEC A;  1ULV A;  3VD9 A;  1L7K A;  1F4H A;  3VDA A;  1N7R A;  2WVX A;  3T08 A;  3MUY 1;  1LXM A;  3DYP A;  3SEP A;  4NEI A;  1EGU A;  2CIR A;  3DYM A;  3I3E A;  1UG9 A;  3NFV A;  1LXK A;  1HMU A;  1J0M A;  5JMF A;  2HTB A;  2Q1F A;  4D6C A;  1MMX A;  1CB8 A;  3T09 A;  1JZ4 A;  3OBA A;  3VDB A;  2WMI A;  4F10 A;  1X1J A;  1RW9 A;  1NKG A;  1F9G A;  3A0O A;  3DCD A;  1JYW A;  2ZXQ A;  3T2O A;  3E1F 1;  4D6J A;  2JKP A;  4D72 A;  4BZE A;  3VD7 A;  4OK2 A;  1HN1 A;  1NSR A;  1JZ5 A;  2X03 A;  1JZ6 A;  3K25 A;  2CIS A;  3NRE A;  2WW3 A;  4RNL A;  1NS2 A;  3T2P A;  2E22 A;  1K1X A;  1RWG A;  1OJN A;  1HM3 A;  4BZG A;  3VDC A;  1K1Y A;  3MWX A;  1NSX A;  4DUW A;  1HV6 A;  1NSU A;  4OZW A;  3VD3 A;  1PX3 A;  2WMF A;  4D6E A; 
#chains in the Genus database with same CATH topology
 2W0Q A;  1TQV A;  3SAE A;  1GA2 A;  2G02 A;  3HII A;  4LNV A;  5CD2 A;  3RX8 A;  2ZQ0 A;  1H37 A;  1W3Y A;  1TN8 B;  3E7J A;  4KFD A;  3MUZ 1;  5EAS A;  2F7P A;  1TNO B;  2HTA A;  3E80 A;  4D4B A;  1LVN A;  2CWV A;  4FNS A;  1GLM A;  4AYQ A;  2GH4 A;  3DDF A;  3I3B A;  1RJO A;  1N7N A;  4KTP A;  2AFA A;  3ANK A;  3N0G A;  1KKT A;  3PZ2 B;  1IQX A;  1LD8 B;  3BUI A;  4FXK B;  1HM2 A;  1FT2 B;  1HXC A;  2R2L B;  3DSU B;  1H3A A;  4D6F A;  1NSS A;  3T0D A;  3QG0 A;  3J7H A;  1WMP A;  2OOV A;  1QQF A;  3VD4 A;  4GTT B;  1LTX B;  1HCU A;  5CZL A;  4FNV A;  3G6J B;  1OJP A;  1HMW A;  2A8Z A;  1N7P A;  3A3V A;  4OK4 A;  3S4A A;  3W7W A;  1PX4 A;  3VSM A;  1MMZ A;  4FNR A;  1WZZ A;  4WVC A;  2QNO A;  3WVF A;  2FV0 A;  5JPN B;  3H7L A;  3M74 A;  1SO0 A;  2BRP A;  2WVZ A;  3MPH A;  2WDA A;  5M7Y A;  2WMI B;  2WMH A;  1X9D A;  1SA4 B;  2FUT A;  1D6Y A;  1IQY A;  2OQE A;  1NSM A;  2XSG A;  3RJ3 A;  5IL3 A;  4KKJ A;  5ILD A;  3M73 A;  1GAH A;  1SQC A;  2WYN A;  4GTV B;  3BS6 A;  3DX4 A;  3PZ3 B;  1O7D D;  2FBA A;  4Z4L A;  4BTY A;  1FCE A;  1NSV A;  4D1J A;  1JZ7 A;  1W2Z A;  1TN7 B;  1LD7 B;  3MV1 1;  2V8I A;  3T0B A;  2BRV X;  1LF6 A;  1O6R A;  2P0V A;  3M00 A;  3WKF A;  1F9D A;  1ULV A;  1AVL A;  3EJP A;  1L7K A;  3P5P A;  3T08 A;  4QT9 A;  2V8K A;  1W4N A;  3F59 A;  4AYO A;  3TF4 A;  4NEI A;  2H6F B;  4EV5 A;  3AMO A;  1N4P B;  3I3E A;  3KSL B;  3QPF A;  1HMU A;  2AHG A;  2EAC A;  2ONH A;  1MMX A;  3EU8 A;  3CZN A;  3D3I A;  3DSW B;  1JZ4 A;  3OBA A;  1QAK A;  3VDB A;  5IK0 A;  2WMI A;  1CEM A;  2CQS A;  2GOX A;  1W7C A;  3REN A;  1JYW A;  1FMI A;  2D5J A;  2V8J A;  3MI6 A;  4Q88 A;  2E2T A;  2WOH A;  1IVU A;  4D6J A;  4BZE A;  2Z07 A;  4DLO A;  3KN4 A;  3VD7 A;  1W6K A;  4OK2 A;  1H3B A;  1O1S B;  1SA5 B;  1NSR A;  3X41 A;  2C10 A;  3GT5 A;  4ZG8 A;  4KFE A;  1V7X A;  3UD2 A;  1SII A;  5ILZ A;  3BUB A;  3PYB A;  1HM3 A;  3Q7A B;  2CFW A;  3KQ4 A;  1KWF A;  1K1Y A;  4D4D A;  1HV6 A;  5ILJ A;  2JJB A;  4OZW A;  1HTY A;  3H3K A;  3QSP A;  3QRY A;  1F9O A;  3NJV A;  4KFF A;  2DRS A;  2KXS A;  2WZS A;  4E1Y A;  3SDT A;  1OAC A;  1TU5 A;  4TXT A;  3W7T A;  3ECQ A;  3ACS A;  1H36 A;  5KBP A;  4YCR A;  4BZH A;  3QFY A;  1IU7 A;  1TQS A;  1LF9 A;  2BED B;  4GL3 A;  5IKH A;  1RWA A;  4Z4J A;  4BOK A;  3Q73 B;  1N23 A;  1GSZ A;  3ANI A;  2WW1 A;  3OS7 A;  2WIN B;  5JPM B;  2PMV A;  2CIQ A;  4J5T A;  1JZ2 A;  1D6Z A;  3X3Y A;  1HZF A;  2BB6 A;  1G87 A;  2BRW A;  1C82 A;  1J0N A;  3D50 A;  3QT9 A;  3BUD A;  4WVB A;  3G4D A;  1RQ5 A;  3KLS A;  1HX9 A;  1KZO B;  2WMJ A;  2XQW A;  3DDG A;  3T0U A;  3T33 A;  3T2Q A;  2EAE A;  5GY3 A;  2WVY A;  3M7L A;  2NOJ A;  1UI8 A;  5DGR A;  3PZ4 B;  4GTM B;  1GXM A;  1N4R B;  1N7Q A;  1S63 B;  3Q78 B;  4DUV A;  1GHQ A;  2ZIR B;  3E33 B;  3SDQ A;  3KBU C;  3SFX B;  3BVU A;  1WU4 A;  1N94 B;  3SXX A;  1MMU A;  1N24 A;  3QFZ A;  1AV4 A;  3Q1N A;  3WA3 A;  1L1Y A;  2WMK A;  5EAU A;  4TTG A;  3M76 A;  3AFJ A;  3VW5 A;  1K1W A;  2PNC A;  1N21 A;  3CU7 A;  3E34 B;  2OW7 A;  2DRQ A;  4WU0 A;  1DCE B;  2ZZR A;  3S4B A;  1WMO A;  4GTO B;  1HN0 A;  2G0D A;  1QWU A;  2FYV A;  3Q7F B;  1R76 A;  3I3D A;  2OW6 A;  3BLB A;  1G6I A;  4ONT A;  1FPP B;  5FOB B;  3AMO B;  2E2U A;  3NBB A;  4D6H A;  1HXG A;  4XUV A;  4BZF A;  3HXE B;  4FUS A;  4BOJ A;  3WKH A;  1KZP B;  1JCS B;  1N4S B;  1H12 A;  1FO2 A;  1W6C A;  3DEC A;  4FNT A;  1H39 A;  3DX2 A;  3VD9 A;  3KSQ B;  3CV5 A;  3VDA A;  5FO9 B;  3K7X A;  3BLC A;  1N7R A;  2E2V A;  3E6U A;  2YIK A;  1EGU A;  3M01 A;  3DYM A;  3M7C A;  1TNU B;  3D5S A;  1RKY A;  2ONG A;  3EJS A;  4ZRQ A;  1J0M A;  5JMF A;  1SPU A;  2V3N A;  2F7O A;  4Q2B A;  4V1S A;  4ZH1 A;  3E30 B;  3KII A;  3W7S A;  1V5D A;  4LNG B;  1TQU A;  3T2O A;  1UI7 A;  2OKX A;  1QX1 A;  4D72 A;  4GAX A;  3X3X A;  3P2C A;  1JZ5 A;  2X03 A;  3D51 A;  3M71 A;  1JZ6 A;  3K25 A;  1H35 A;  3D4Y A;  1O1T B;  4FNP A;  2E22 A;  4GTR B;  4RNQ A;  1RWG A;  1OJN A;  3Q79 B;  2OOV C;  3QWT A;  3DSV B;  3G4F A;  4BZG A;  2H6H B;  2F1B A;  3VD3 A;  4CJ0 A;  2RI8 A;  2EAB A;  1NXC A;  1RWC A;  1HXA A;  2A73 B;  1GXO A;  3S4D A;  3W5M A;  3A24 A;  2H6G B;  3NBJ A;  3LVT A;  3WUX A;  4JJJ A;  1QSJ A;  1D6U A;  1IVV A;  3M7B A;  5EAT A;  2JG0 A;  1N4Q B;  1R34 A;  1XW2 A;  2GZ6 A;  4D4A A;  1SIH A;  1H3C A;  1IA6 A;  2OQE C;  4FXG B;  3QXF A;  4CJ1 A;  1JRQ A;  1H54 A;  4TF4 A;  1NC5 A;  3PYA A;  3VXD A;  1R33 A;  1FP3 A;  3ACT A;  2WW0 A;  1UMP A;  2RGK A;  1XWT A;  1JCQ B;  4KTR A;  4V1R A;  4L9P B;  1SNZ A;  1JZ3 A;  2XHN A;  1JS4 A;  5DHI A;  4DI5 A;  3TY1 A;  3K5T A;  3LOY A;  1RWH A;  1MN0 A;  1D8D B;  2B39 A;  1DP0 A;  1O5M B;  3EZ8 A;  1O6H A;  3GLY A;  3MV0 1;  3VD5 A;  1X81 B;  2Y73 A;  3GZK A;  3IMH A;  2F0Y B;  4AYP A;  2ALW A;  2F18 A;  4D71 A;  4YDE B;  3BVV A;  3E32 B;  3QT3 A;  1LOH A;  4D1I A;  1W6J A;  3CZJ A;  5DHK A;  3WC3 A;  1L7J A;  1CLC A;  1QAZ A;  2RDY A;  2BBC A;  1H13 A;  4BTX A;  5AGD A;  4YDO B;  2E24 A;  1JZ8 A;  1O79 A;  4D6G A;  1F4A A;  2Y74 A;  4FJQ A;  1N7O A;  1W6G A;  2CFL A;  2JKE A;  1JYV A;  1F1S A;  1AYX A;  2BB5 A;  5MEH A;  3C72 B;  2WO0 A;  2YFO A;  3SDU A;  3QR8 A;  3CIH A;  2H6I B;  1KSI A;  3E73 A;  1NS4 A;  2CG0 A;  3BVW A;  3DX3 A;  3HXF B;  1JYN A;  2C11 A;  2JKA A;  1V7V A;  1N1B A;  3EJR A;  1TF4 A;  5CA3 A;  5JMD A;  4D8O A;  3ON6 A;  2D1W A;  1IA7 A;  1RWF A;  2F7Q A;  1UT9 A;  2AHF A;  3EU5 B;  2CWT A;  2WY7 A;  5FO7 B;  1YQ2 A;  1FT1 B;  3HXD B;  4MMH A;  5IL8 A;  4DLQ A;  1I8Q A;  3HIG A;  3SQC A;  3WKI A;  3KBT C;  1LUR A;  4BTW A;  2XN2 A;  4UFC A;  1F4H A;  1KS8 A;  4MBG B;  1H14 A;  5ILI A;  2CIR A;  3BUP A;  3EJQ A;  5ILY A;  1UG9 A;  3D4Z A;  2WII B;  3ANJ A;  4KKI A;  4MU9 A;  4GTQ B;  2Q1F A;  2IEJ B;  3W7U A;  2DRR A;  4EHM B;  2XFG A;  1X1J A;  4F10 A;  1W5Z A;  2PN5 A;  1RW9 A;  1NKG A;  1F9G A;  3DCD A;  3W5N A;  1V5C A;  2RI9 A;  2ZXQ A;  3PMM A;  2XWB B;  1N20 A;  2VN7 A;  3RX5 A;  3H2W A;  1O1R B;  2CQT A;  1FO3 A;  2WOF A;  3D5R A;  1O6Q A;  5FO8 B;  1QBQ B;  3SX1 A;  1KFG A;  2XN0 A;  3DRA B;  4GTP B;  1MZC B;  3EQA A;  1NS2 A;  1TQW A;  3T2P A;  1QAL A;  3LZ9 A;  1K1X A;  1WU5 A;  1FBW A;  1C3D A;  2CFK A;  3DX1 A;  3X40 A;  3VDC A;  5ILH A;  1NSX A;  3ALA A;  2B4F A;  2CWU A;  3BVT A;  5IM1 A;  1S64 B;  3HXC B;  3DST B;  5GZK A;  1PX3 A;  4GTS B;  2WMF A;  1N9E A;  1FAE A;  2JF4 A;  3DPY B;  3M72 A;  2YFN A;  1NS0 A;  3IAQ A;  3T0A A;  4MMI A;  1IVW A;  1TXK A;  3NJX A;  2XN1 A;  2J5C A;  1G9G A;  5E1Q A;  2SQC A;  1NL4 B;  1TNB B;  3BUQ A;  2D8L A;  1PU4 A;  1DOG A;  3S4C A;  5M7I A;  1JYX A;  1HXK A;  2EAD A;  3S9V A;  2WYH A;  3RRS A;  2WYI A;  3E37 B;  5IK9 A;  4FNU A;  1JCR B;  1AGM A;  5IK6 A;  4ZH5 A;  4K3A A;  1TN6 B;  2NVP A;  1OJM A;  2WMG A;  4D4C A;  4D94 A;  3X3Z A;  3UD1 A;  4EV2 A;  3QXQ A;  1K72 A;  5DGQ A;  5A1A A;  2WVX B;  2FUQ A;  3M77 A;  1VD5 A;  3WIW A;  3M7E A;  4F13 A;  4D6I A;  1US1 A;  3M75 A;  4D6D A;  3QDE A;  4DUX A;  1OJO A;  2CFG A;  2WY8 A;  2ZBL A;  1NS7 A;  3OB8 A;  1MMY A;  1PS3 A;  3DYO A;  4L0G A;  3WIQ A;  3RSY A;  1TNZ B;  3WKG A;  3VSN A;  2WW2 A;  4EL8 A;  4LNB B;  3EJU A;  1NS8 A;  3WFA A;  3PQI A;  2VN4 A;  4WVA A;  1X1I A;  1N1Z A;  4DOD A;  4CE7 A;  1DL2 A;  1IVX A;  2CG1 A;  2WCO A;  3EUV B;  1NSZ A;  3BGA A;  1JOV A;  4AYR A;  1FBO A;  3M78 A;  3NNB A;  2WGQ A;  3D52 A;  3M02 A;  1DYU A;  3SDR A;  3EJT A;  1YGA A;  1X1H A;  3P5R A;  1Z45 A;  2D73 A;  4OZV A;  1V7W A;  1KSD A;  3DX0 A;  4AQ0 A;  4OJZ A;  3IAP A;  3OXU A;  3PGB A;  2F6D A;  1A2V A;  2BT3 A;  3AFL A;  3BVX A;  3HI7 A;  3X42 A;  2F7R A;  3SDV A;  5ILK A;  1D8E B;  5C05 A;  1GAI A;  4LIX A;  3Q75 B;  1KRF A;  3CZS A;  2WVX A;  4K35 A;  3MUY 1;  1LXM A;  5GW7 A;  3PZ1 B;  5IKA A;  3DYP A;  3N9H A;  3SEP A;  1WU6 A;  1N22 A;  1XWQ A;  3DSS B;  1TNY B;  1L2A A;  3NFV A;  1LXK A;  4L6X A;  1N9A B;  4DOE A;  2HTB A;  4D6C A;  1CB8 A;  3T09 A;  2KXR A;  5KKB A;  1G9J A;  2V3P A;  1AVK A;  3K11 A;  2F1A A;  3HXB B;  3A0O A;  3RX7 A;  1IS9 A;  1TQT A;  3E1F 1;  2JKP A;  3W7X A;  1HN1 A;  1N95 B;  2DRO A;  2CFD A;  3X17 A;  3WA2 X;  4ZRP A;  2FUZ A;  2XWJ B;  2CIS A;  3SFY B;  3WIR A;  3DSX B;  3NRE A;  1EKM A;  2WW3 A;  2YX9 A;  3N0F A;  4RNL A;  1KSC A;  2ZIS B;  1WMN A;  1NI1 B;  1QAF A;  3U7V A;  1KRE A;  3OED A;  1GXN A;  1QWN A;  2FV1 A;  3MWX A;  2ZL8 A;  1HWW A;  4FNQ A;  4DUW A;  4C1S A;  1NSU A;  5E2J A;  4M76 A;  2I07 B;  4D6E A; 
#chains in the Genus database with same CATH homology
 3A24 A;  3IAQ A;  3NJV A;  1NS0 A;  2WZS A;  3T0A A;  4MMI A;  4E1Y A;  1TXK A;  3NJX A;  2ZQ0 A;  1W3Y A;  3E7J A;  3ECQ A;  3MUZ 1;  4BZH A;  5E1Q A;  2HTA A;  3E80 A;  1LF9 A;  1RWA A;  3I3B A;  1N7N A;  1JYX A;  2WW1 A;  2WW0 A;  3OS7 A;  1SNZ A;  2CIQ A;  4J5T A;  1JZ2 A;  1RWC A;  1JZ3 A;  2XHN A;  1OJM A;  3TY1 A;  2WMG A;  2BRW A;  1RWH A;  1C82 A;  1J0N A;  1MN0 A;  1DP0 A;  1HM2 A;  4D6F A;  3T0D A;  1NSS A;  3MV0 1;  3VD5 A;  5A1A A;  2WVX B;  3J7H A;  3IMH A;  2FUQ A;  4D6I A;  2WMJ A;  4F13 A;  3T2Q A;  3VD4 A;  4D6D A;  4D71 A;  1OJO A;  2WVY A;  4DUX A;  4FNV A;  1NS7 A;  1OJP A;  1HMW A;  4OK4 A;  1N7P A;  1PX4 A;  3OB8 A;  1MMY A;  3DYO A;  4TTG A;  3VSM A;  1MMZ A;  1N7Q A;  1LOH A;  4DUV A;  3CZJ A;  3WVF A;  3VSN A;  2WVZ A;  2WW2 A;  1L7J A;  2BRP A;  1SO0 A;  1QAZ A;  2WDA A;  2WMI B;  1NS8 A;  2WMH A;  2FUT A;  3WFA A;  2E24 A;  1JZ8 A;  1MMU A;  1X1I A;  4D6G A;  1F4A A;  3Q1N A;  2WMK A;  2WCO A;  1K1W A;  1NSM A;  1N7O A;  2JKE A;  1NSZ A;  2XSG A;  1JYV A;  1F1S A;  1JOV A;  3BGA A;  3NNB A;  1NS4 A;  3BS6 A;  1JYN A;  1HN0 A;  2JKA A;  1YGA A;  1X1H A;  5JMD A;  1Z45 A;  1NSV A;  3I3D A;  1JZ7 A;  1RWF A;  2D73 A;  4OZV A;  1YQ2 A;  4AQ0 A;  3MV1 1;  4MMH A;  4OJZ A;  4D6H A;  3IAP A;  3T0B A;  4BZF A;  1I8Q A;  2BRV X;  1LF6 A;  1LUR A;  3AFL A;  3DEC A;  1ULV A;  3VD9 A;  1L7K A;  1F4H A;  3VDA A;  3BLC A;  1N7R A;  2WVX A;  3T08 A;  3MUY 1;  1LXM A;  3DYP A;  3SEP A;  4NEI A;  1EGU A;  2CIR A;  3DYM A;  3I3E A;  1UG9 A;  3NFV A;  1LXK A;  1HMU A;  1J0M A;  5JMF A;  2HTB A;  2Q1F A;  4D6C A;  1MMX A;  1CB8 A;  3T09 A;  1JZ4 A;  3OBA A;  3VDB A;  2WMI A;  4F10 A;  1X1J A;  1RW9 A;  1NKG A;  1F9G A;  3A0O A;  3DCD A;  1JYW A;  2ZXQ A;  3T2O A;  3E1F 1;  4D6J A;  2JKP A;  4D72 A;  4BZE A;  3VD7 A;  4OK2 A;  1HN1 A;  1NSR A;  1JZ5 A;  2X03 A;  1JZ6 A;  3K25 A;  2CIS A;  3NRE A;  2WW3 A;  4RNL A;  1NS2 A;  3T2P A;  2E22 A;  1K1X A;  1RWG A;  1OJN A;  1HM3 A;  4BZG A;  3VDC A;  1K1Y A;  3MWX A;  1NSX A;  4DUW A;  1HV6 A;  1NSU A;  4OZW A;  3VD3 A;  1PX3 A;  2WMF A;  4D6E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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