1HMWA

Active site of chondroitinase ac lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis
Total Genus 236
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
236
sequence length
674
structure length
674
Chain Sequence
b'GTAELIMKRVMLDLKKPLRNMDKVAEKNLNTLQPDGSWKDVPYKDDAMTNWLPNNHLLQLETIIQAYIEKDSHYYGDDKVFDQISKAFKYWYDSDPKSRNWWHNEIATPQALGEMLILMRYGKKPLDEALVHKLTERMKRGEPEKKTGANKTDIALHYFYRALLTSDEALLSFAVKELFYPVQFVHYEEGLQYDYSYLQHGPQLQISSYGAVFITGVLKLANYVRDTPYALSTEKLAIFSKYYRDSYLKAIRGSYMDFNVEGRGVSRPDILNKKAEKKRLLVAKMIDLKHTEEWADAIARTDSTVAAGYKIEPYHHQFWNGDYVQHLRPAYSFNVRMVSKRTRRSESGNKENLLGRYLSDGATNIQLRGPEYYNIMPVWEWDKIPGITSRDYLTDRPLTKLWGEQGSNDFAGGVSDGVYGASAYALDYDSLQAKKAWFFFDKEIVCLGAGINSNAPENITTTLNQSWLNGPVISTAGKTGRGKITTFKAQGQFWLLHDAIGYYFPEGANLSLSTQSQKGNWFHINNSHSKDEVSGDVFKLWINHGARPENAQYAYIVLPGINKPEEIKKYNGTAPKVLANTNQLQAVYHQQLDMVQAIFYTAGKLSVAGIEIETDKPCAVLIKHINGKQVIWAADPLQKEKTAVLSIRDLKTGKTNRVKIDFPQQEFAGATVEL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords CHONDROITINASE AC
publication title Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis.
pubmed doi rcsb
source organism Pedobacter heparinus
molecule tags Lyase
total genus 236
structure length 674
sequence length 674
ec nomenclature ec 4.2.2.5: Chondroitin AC lyase.
pdb deposition date 2000-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1hmwA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1hmwA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1hmwA02
1F9GA 3DECA 1LXMA 3T09A 1LXKA 4AQ0A 3K25A 5A1AA 4RNLA 1LOHA 3E7JA 3NFVA 4OK2A 2E22A 3NJVA 1N7PA 3T2OA 1X1HA 3T0AA 1PX3A 1I8QA 3NJXA 1L7JA 1N7OA 3AFLA 1K1XA 4MMIA 3Q1NA 2E24A 3NNBA 2WMIA 1F4AA 1ULVA 2HTBA 4F10A 2D73A 4OJZA 4D6DA 1HN1A 1NS4A 1MMUA 1YGAA 3E1F1 2WMHA 2WVXB 4MMHA 3BGAA 4TTGA 4DUXA 1JOVA 3T08A 3VSNA 1RW9A 1NS8A 2JKAA 1NSUA 1K1YA 1MMZA 3VD5A 4D6HA 2JKPA 2ZQ0A 1NSMA 1C82A 1NS0A 1NS2A 1L7KA 3IMHA 2CIRA 1QAZA 3SEPA 2WMKA 2HTAA 2BRVX 2JKEA 1YQ2A 2WVYA 2XHNA 3ECQA 3T2QA 1JZ3A 3I3BA 1MN0A 4D6CA 3T0DA 3MUY1 2WCOA 1NS7A 4D6IA 1MMXA 3WFAA 4D72A 1LF6A 3DYMA 4D6FA 2WW1A 3VDCA 4OK4A 1EGUA 1HMWA 4D71A 3OBAA 1X1JA 3I3DA 5E1QA 5JMFA 1JYXA 1LURA 3VD9A 4OZVA 2WZSA 3DCDA 1NKGA 3VSMA 2WMGA 3MWXA 2X03A 3VD3A 1CB8A 4DUWA 2WMIB 1Z45A 1HMUA 1JZ5A 1NSVA 2WMFA 1NSSA 1NSRA 3T2PA 4BZHA 4DUVA 1JYWA 3E80A 2ZXQA 3OB8A 3A0OA 3T0BA 1J0NA 1LF9A 1N7QA 1JZ4A 1OJOA 1W3YA 1NSXA 2FUQA 3A24A 3DYOA 1HN0A 2WVZA 3IAQA 1NSZA 1JZ7A 1RWHA 2WW0A 1JZ2A 4BZGA 1RWFA 1RWAA 2WW2A 2BRWA 3CZJA 1MMYA 1OJNA 2CIQA 4BZEA 1JZ6A 2BRPA 1RWCA 1DP0A 4NEIA 2WVXA 1JZ8A 1OJPA 1F4HA 3NREA 1UG9A 1RWGA 1HM2A 4BZFA 1SO0A 1N7NA 2Q1FA 1JYVA 3J7HA 2CISA 1X1IA 1J0MA 4OZWA 2WMJA 1F1SA 4D6EA 2XSGA 3I3EA 3VD4A 1TXKA 3VDBA 2WDAA 1SNZA 1HM3A 3MV01 3DYPA 1HV6A 3OS7A 4D6JA 1K1WA 3MUZ1 2FUTA 3MV11 1N7RA 4F13A 5JMDA 1OJMA 4D6GA 3VD7A 4FNVA 4E1YA 2WW3A 3IAPA 1PX4A 1JYNA 3VDAA
chains in the Genus database with same CATH superfamily
2RDYA 5EASA 1N23A 3K25A 3BUPA 2CWUA 1N4SB 3E7JA 4OK2A 4K35A 3QSPA 1N22A 1G87A 1AV4A 1UI7A 3T2OA 1FT1B 3T0AA 3MPHA 1I8QA 3Q7FB 1X9DA 4KFEA 1KWFA 1L7JA 2A8ZA 1QALA 5IL8A 1KFGA 2E24A 1NXCA 1IA6A 3NNBA 5FO7B 3X40A 2HTBA 2FV0A 4GTQB 1HCUA 1HXAA 4WVCA 1H37A 5DGQA 3E1F1 2WMHA 2H6IB 3K5TA 5GZKA 1W5ZA 2AHFA 1JOVA 4C1SA 2JJBA 4QT9A 1HTYA 2V8JA 1NS8A 5IK9A 1QAKA 1FBOA 4GAXA 1NSUA 2ZZRA 2CFGA 1LD7B 3VD5A 4D6HA 1H13A 2JKPA 1NSMA 4D8OA 1V7VA 5E2JA 3QRYA 1QAZA 5ILKA 1TN6B 3M7LA 2WMKA 2JKEA 4ZG8A 3T2QA 2E2UA 3ECQA 4J5TA 2CFLA 3RX5A 2E2TA 1H12A 2DRRA 3I3BA 3QFYA 3VW5A 4UFCA 2F7QA 2G02A 2WCOA 4AYQA 4D4BA 1LF6A 4LIXA 4BTYA 3H3KA 3M7BA 2F7RA 3DYMA 1GXMA 4D6FA 2CFWA 2WW1A 3VDCA 4OK4A 1N4RB 3S4CA 3DDFA 1EGUA 1X1JA 2Z07A 5DGRA 5E1QA 4FNQA 1LURA 4GTVB 3M01A 1GAIA 1IVWA 1NI1B 1OACA 3VSMA 2WMGA 3KIIA 1CB8A 1US1A 4DUWA 1GHQA 1MZCB 3M00A 3QPFA 1W2ZA 1HMUA 1WMOA 3EJPA 4GTOB 1NSSA 4DUVA 2B39A 1O7DD 2CQSA 5EAUA 1QWUA 1O1SB 2YFOA 1G6IA 3T0BA 2XN0A 1AGMA 3H7LA 1LF9A 1KSCA 1N4QB 1N7QA 3TF4A 4WU0A 2JF4A 3QDEA 3A24A 3D5SA 1HN0A 1XW2A 1TNZB 1IS9A 4KKIA 3BUDA 2XFGA 3N0GA 1PU4A 2D5JA 2W0QA 1JZ2A 1GAHA 3ACTA 1MMYA 4BZEA 2F7PA 4TF4A 2DRQA 1JZ6A 2BRPA 1HXKA 3DSSB 1O1TB 1N1BA 3D50A 3W5NA 1F4HA 3LOYA 1HM2A 4BZFA 2WIIB 5IL3A 3W5MA 1KRFA 3J7HA 1G9JA 2VN7A 4OZWA 3X17A 5M7IA 5ILYA 1TQSA 2YX9A 1N9AB 1V7XA 3HXDB 3SAEA 3VDBA 2WDAA 1SNZA 1WMPA 1WZZA 3D5RA 1IA7A 3SXXA 4FXGB 3KSLB 5GW7A 3D4YA 3QR8A 3IAPA 1F9GA 2WY8A 1WU5A 4AQ0A 3HXEB 1IVXA 1AVLA 4DI5A 5A1AA 3GT5A 2ZBLA 4RNLA 1LOHA 1PS3A 3NJVA 4ONTA 1D8DB 2FYVA 1N7PA 1L2AA 2GH4A 2D1WA 2XWJB 3E6UA 3HXCB 3EUVB 4V1SA 4BTWA 3NJXA 3DX3A 3M78A 1TN7B 3GZKA 3RX7A 4AYOA 5ILZA 3BVVA 3NBJA 2BEDB 3NBBA 3Q1NA 3HXBB 4XUVA 1F4AA 4F10A 2NVPA 1NS4A 1MMUA 3S4BA 1YGAA 1W6JA 2WVXB 3BGAA 3WKGA 3E73A 1GA2A 1NL4B 1G9GA 2QNOA 3W7TA 3VSNA 3HIIA 4AYPA 3SFYB 2CG1A 2JKAA 4ZH5A 2IEJB 2WYNA 4Q2BA 3EJQA 1RKYA 3ANKA 1NS2A 2F7OA 2OQEC 4FXKB 3D51A 3W7XA 2OOVC 3DPYB 3M75A 4D1IA 1IVVA 1O6HA 2HTAA 2BRVX 2OW7A 2WVYA 1H54A 2H6GB 3E34B 1JZ3A 3P5RA 1FO3A 1IQXA 1GLMA 2F0YB 2OQEA 4D6CA 2XN2A 3T0DA 2WINB 2F1AA 1NS7A 3S4DA 3EJTA 3WKFA 5FO9B 4D94A 1N4PB 1HMWA 1FP3A 3PYAA 3OBAA 1SA5B 3I3DA 4FNTA 2WZSA 4CE7A 3TY1A 2BB5A 2C10A 2XN1A 3HXFB 2F18A 1DL2A 3WKIA 1Z45A 1SIIA 3X3YA 5IM1A 1R34A 4BTXA 3G4FA 3WVFA 4BZHA 3PZ2B 1CEMA 1LVNA 4YCRA 3RSYA 4FNUA 3BVWA 2WOFA 1OJOA 5CD2A 3WIWA 2FUQA 1TNYB 3SDVA 3IAQA 1JZ7A 5IK6A 1GSZA 2V3NA 2BRWA 1D6ZA 1FPPB 1JCQB 3M76A 4WVBA 1RWCA 3D3IA 3M72A 4NEIA 3BVXA 2OW6A 1KREA 1JZ8A 1N21A 3DX0A 1OJPA 3DX2A 3OXUA 1RWGA 3WKHA 4Z4LA 1N7NA 4ZRQA 5MEHA 1QSJA 4GTTB 1D8EB 1X1IA 1J0MA 2WMJA 1F1SA 2KXSA 3W7WA 4Z4JA 1TNBB 2R2LB 3I3EA 3VD4A 2I07B 3EQAA 3PZ3B 1HM3A 1SQCA 3DYPA 4D6JA 5KBPA 2FUTA 5DHIA 3MV11 4D4CA 4F13A 3M7EA 1TQWA 1QQFA 3H2WA 3K7XA 3M02A 1O5MB 3DSTB 3CIHA 1UT9A 1DOGA 2FBAA 3RX8A 1HXGA 1KZPB 1S64B 1N9EA 2CFKA 3T09A 4EV5A 4GTRB 5JPNB 1N20A 3NFVA 2E22A 1WMNA 1LD8B 4KTRA 1R76A 4LNBB 1O79A 2WO0A 1K1XA 4KKJA 4MMIA 3X41A 3SFXB 2WMIA 4DODA 1QWNA 1ULVA 3E30B 2D73A 4D6DA 2CWVA 5DHKA 1F9OA 3PYBA 4MMHA 1NC5A 4TTGA 4BOKA 1FO2A 4DUXA 2EACA 3S9VA 2CWTA 2ZL8A 1FBWA 2H6FB 1LTXB 3M73A 3QWTA 1MMZA 3WA2X 2ZQ0A 3QFZA 1C82A 3T33A 3DSVB 3BVUA 5KKBA 2FUZA 4L0GA 4D4AA 2ZIRB 1HZFA 2AFAA 3HI7A 1UI8A 1YQ2A 4DLOA 1V5DA 3EU5B 1WU4A 4GTMB 3CZNA 3N9HA 3RRSA 3EJRA 3M74A 3E33B 4FNRA 3KLSA 5IKHA 4D72A 5CZLA 3WFAA 3ACSA 2B4FA 1DCEB 1GXOA 1JCSB 5C05A 5ILDA 2JG0A 1R33A 3DSUB 4CJ0A 4D71A 4MU9A 2FV1A 4FJQA 5JMFA 1JS4A 3DCDA 1TN8B 4V1RA 3QG0A 2KXRA 3MWXA 3N0FA 3QT9A 1H3AA 1KS8A 3A3VA 1PX4A 1NSVA 2WMFA 1AVKA 1O6QA 4L9PB 1NSRA 1TQUA 3DX1A 4GTSB 1W4NA 5FO8B 2PNCA 1SIHA 2Y73A 3DRAB 3E80A 1KKTA 3Q75B 2ZXQA 2GZ6A 4D4DA 3DX4A 1XWTA 1JZ4A 3GLYA 5FOBB 2A73B 1W3YA 1NSXA 2YIKA 4TXTA 3DYOA 2CFDA 1JRQA 2OOVA 1NSZA 3C72B 3F59A 1RWHA 2WY7A 3EU8A 2WW0A 1N24A 1RWFA 3CV5A 4BZGA 1RWAA 2WW2A 3CZJA 2CIQA 1OJNA 1TNUB 3DSWB 2F6DA 5CA3A 3M77A 3UD2A 1DP0A 1FAEA 1W6CA 1D6YA 1H3BA 2RI9A 1RJOA 3X3ZA 3NREA 4DOEA 1JYVA 1SO0A 2V8KA 3W7UA 2GOXA 3BUQA 3SDQA 1AYXA 4D6EA 1TXKA 1HX9A 1QX1A 2PN5A 3MV01 1HV6A 3OS7A 3M71A 3SDUA 2BT3A 2CG0A 2YFNA 3OEDA 1N7RA 4D1JA 4GL3A 4D6GA 3ON6A 4FNVA 1WU6A 3ANJA 2RGKA 4E1YA 1TQVA 2D8LA 4WVAA 1IU7A 1JYNA 3DSXB 1L1YA 1V5CA 3T0UA 3DECA 1LXMA 3PQIA 1LXKA 2WOHA 3KBUC 4JJJA 1UMPA 3RJ3A 1D6UA 5ILIA 2DRSA 5ILHA 2C11A 1TF4A 1X1HA 3BUBA 3SX1A 1TQTA 1PX3A 1QAFA 1W6GA 3WIRA 2XQWA 2EABA 3QXQA 4KFFA 1N7OA 2PMVA 2VN4A 1XWQA 3AFLA 4AYRA 3PZ1B 2ALWA 3X42A 3Q7AB 3UD1A 3AMOA 4OJZA 1DYUA 1X81B 1HN1A 1H35A 1FMIA 4L6XA 1VD5A 4FUSA 2WYHA 3BLCA 4FNPA 1HWWA 1N1ZA 5AGDA 4CJ1A 2WGQA 3T08A 4ZH1A 2DROA 3P5PA 1FT2B 1RW9A 2ONGA 4EL8A 3WC3A 5ILJA 3ALAA 1F9DA 4MBGB 1K1YA 3PMMA 2WYIA 4FNSA 3AMOB 1GXNA 5GY3A 4KTPA 1NS0A 3X3XA 1L7KA 3IMHA 2CIRA 1H39A 3SEPA 2NOJA 3PZ4B 1W7CA 2BB6A 3G4DA 1H36A 2XHNA 5IK0A 2F1BA 2G0DA 3G6JB 3KSQB 2V8IA 3CU7A 5EATA 1KSIA 3E32B 1MN0A 4BOJA 3MUY1 2ZISB 4ZRPA 4D6IA 1MMXA 3KN4A 2BBCA 3QT3A 2RI8A 1JYXA 3VD9A 3PGBA 3LZ9A 4OZVA 4M76A 1RQ5A 1NKGA 3D52A 1C3DA 3VXDA 4DLQA 2X03A 3VD3A 1S63B 4K3AA 2WMIB 1TU5A 4LNVA 1JZ5A 4EV2A 1QBQB 3E37B 5JPMB 2V3PA 3Q73B 1TNOB 4YDEB 3MI6A 3HIGA 1JYWA 1CLCA 3EJUA 1H14A 1O6RA 3A0OA 1J0NA 3SQCA 3BVTA 3D4ZA 3OB8A 1N95B 3EJSA 3WA3A 1JCRB 1K72A 3SDRA 1SPUA 3RENA 2E2VA 3ANIA 4YDOB 2WVZA 2J5CA 1W6KA 3EZ8A 2AHGA 3S4AA 4LNGB 2OKXA 3Q79B 1FCEA 2EADA 3KQ4A 3LVTA 2SQCA 3AFJA 3WIQA 2ONHA 3KBTC 2H6HB 2WVXA 3T2PA 3DDGA 1UG9A 2Q1FA 3P2CA 1A2VA 3K11A 3QXFA 1V7WA 4EHMB 1EKMA 2CISA 3SDTA 1N94B 1HXCA 2EAEA 1H3CA 3BLBA 2P0VA 1KZOB 2XSGA 1KSDA 3BUIA 4GTPB 3U7VA 5IKAA 3M7CA 1IQYA 1O1RB 4RNQA 1K1WA 3MUZ1 3BS6A 1IVUA 4Q88A 5JMDA 1OJMA 3Q78B 3CZSA 1SA4B 3W7SA 3VD7A 5M7YA 4KFDA 3WUXA 2Y74A 2WW3A 2XWBB 2CQTA 3VDAA
chains in the Genus database with same CATH topology
1F9GA 3DECA 1LXMA 3T09A 1LXKA 4AQ0A 3K25A 5A1AA 4RNLA 1LOHA 3E7JA 3NFVA 4OK2A 2E22A 3NJVA 1N7PA 3T2OA 1X1HA 3T0AA 1PX3A 1I8QA 3NJXA 1L7JA 1N7OA 3AFLA 1K1XA 4MMIA 3Q1NA 2E24A 3NNBA 2WMIA 1F4AA 1ULVA 2HTBA 4F10A 2D73A 4OJZA 4D6DA 1HN1A 1NS4A 1MMUA 1YGAA 3E1F1 2WMHA 2WVXB 4MMHA 3BGAA 4TTGA 4DUXA 3BLCA 1JOVA 3T08A 3VSNA 1RW9A 1NS8A 2JKAA 1NSUA 1K1YA 1MMZA 3VD5A 4D6HA 2JKPA 2ZQ0A 1NSMA 1C82A 1NS0A 1NS2A 1L7KA 3IMHA 2CIRA 1QAZA 3SEPA 2WMKA 2HTAA 2BRVX 2JKEA 1YQ2A 2WVYA 2XHNA 3ECQA 3T2QA 4J5TA 1JZ3A 3I3BA 1MN0A 4D6CA 3T0DA 3MUY1 2WCOA 1NS7A 4D6IA 1MMXA 3WFAA 4D72A 1LF6A 3DYMA 4D6FA 2WW1A 3VDCA 4OK4A 1EGUA 1HMWA 4D71A 3OBAA 1X1JA 3I3DA 5E1QA 5JMFA 1JYXA 1LURA 3VD9A 4OZVA 2WZSA 3DCDA 1NKGA 3TY1A 3VSMA 2WMGA 3MWXA 2X03A 3VD3A 1CB8A 4DUWA 2WMIB 1Z45A 1HMUA 1JZ5A 1NSVA 2WMFA 1NSSA 1NSRA 3T2PA 3WVFA 4BZHA 4DUVA 1JYWA 3E80A 2ZXQA 3OB8A 3A0OA 3T0BA 1J0NA 1LF9A 1N7QA 1JZ4A 1OJOA 1W3YA 1NSXA 2FUQA 3A24A 3DYOA 1HN0A 2WVZA 3IAQA 1NSZA 1JZ7A 1RWHA 2WW0A 1JZ2A 4BZGA 1RWFA 1RWAA 2WW2A 2BRWA 3CZJA 1MMYA 1OJNA 2CIQA 4BZEA 1JZ6A 2BRPA 1RWCA 1DP0A 4NEIA 2WVXA 1JZ8A 1OJPA 1F4HA 3NREA 1UG9A 1RWGA 1HM2A 4BZFA 1SO0A 1N7NA 2Q1FA 1JYVA 3J7HA 2CISA 1X1IA 1J0MA 4OZWA 2WMJA 1F1SA 4D6EA 2XSGA 3I3EA 3VD4A 1TXKA 3VDBA 2WDAA 1SNZA 1HM3A 3MV01 3DYPA 1HV6A 3OS7A 4D6JA 1K1WA 3MUZ1 3BS6A 2FUTA 3MV11 1N7RA 4F13A 5JMDA 1OJMA 4D6GA 3VD7A 4FNVA 4E1YA 2WW3A 3IAPA 1PX4A 1JYNA 3VDAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F9G A;  3DEC A;  1LXM A;  3T09 A;  1LXK A;  4AQ0 A;  3K25 A;  5A1A A;  4RNL A;  1LOH A;  3E7J A;  3NFV A;  4OK2 A;  2E22 A;  3NJV A;  1N7P A;  3T2O A;  1X1H A;  3T0A A;  1PX3 A;  1I8Q A;  3NJX A;  1L7J A;  1N7O A;  3AFL A;  1K1X A;  4MMI A;  3Q1N A;  2E24 A;  3NNB A;  2WMI A;  1F4A A;  1ULV A;  2HTB A;  4F10 A;  2D73 A;  4OJZ A;  4D6D A;  1HN1 A;  1NS4 A;  1MMU A;  1YGA A;  3E1F 1;  2WMH A;  2WVX B;  4MMH A;  3BGA A;  4TTG A;  4DUX A;  1JOV A;  3T08 A;  3VSN A;  1RW9 A;  1NS8 A;  2JKA A;  1NSU A;  1K1Y A;  1MMZ A;  3VD5 A;  4D6H A;  2JKP A;  2ZQ0 A;  1NSM A;  1C82 A;  1NS0 A;  1NS2 A;  1L7K A;  3IMH A;  2CIR A;  1QAZ A;  3SEP A;  2WMK A;  2HTA A;  2BRV X;  2JKE A;  1YQ2 A;  2WVY A;  2XHN A;  3ECQ A;  3T2Q A;  1JZ3 A;  3I3B A;  1MN0 A;  4D6C A;  3T0D A;  3MUY 1;  2WCO A;  1NS7 A;  4D6I A;  1MMX A;  3WFA A;  4D72 A;  1LF6 A;  3DYM A;  4D6F A;  2WW1 A;  3VDC A;  4OK4 A;  1EGU A;  1HMW A;  4D71 A;  3OBA A;  1X1J A;  3I3D A;  5E1Q A;  5JMF A;  1JYX A;  1LUR A;  3VD9 A;  4OZV A;  2WZS A;  3DCD A;  1NKG A;  3VSM A;  2WMG A;  3MWX A;  2X03 A;  3VD3 A;  1CB8 A;  4DUW A;  2WMI B;  1Z45 A;  1HMU A;  1JZ5 A;  1NSV A;  2WMF A;  1NSS A;  1NSR A;  3T2P A;  4BZH A;  4DUV A;  1JYW A;  3E80 A;  2ZXQ A;  3OB8 A;  3A0O A;  3T0B A;  1J0N A;  1LF9 A;  1N7Q A;  1JZ4 A;  1OJO A;  1W3Y A;  1NSX A;  2FUQ A;  3A24 A;  3DYO A;  1HN0 A;  2WVZ A;  3IAQ A;  1NSZ A;  1JZ7 A;  1RWH A;  2WW0 A;  1JZ2 A;  4BZG A;  1RWF A;  1RWA A;  2WW2 A;  2BRW A;  3CZJ A;  1MMY A;  1OJN A;  2CIQ A;  4BZE A;  1JZ6 A;  2BRP A;  1RWC A;  1DP0 A;  4NEI A;  2WVX A;  1JZ8 A;  1OJP A;  1F4H A;  3NRE A;  1UG9 A;  1RWG A;  1HM2 A;  4BZF A;  1SO0 A;  1N7N A;  2Q1F A;  1JYV A;  3J7H A;  2CIS A;  1X1I A;  1J0M A;  4OZW A;  2WMJ A;  1F1S A;  4D6E A;  2XSG A;  3I3E A;  3VD4 A;  1TXK A;  3VDB A;  2WDA A;  1SNZ A;  1HM3 A;  3MV0 1;  3DYP A;  1HV6 A;  3OS7 A;  4D6J A;  1K1W A;  3MUZ 1;  2FUT A;  3MV1 1;  1N7R A;  4F13 A;  5JMD A;  1OJM A;  4D6G A;  3VD7 A;  4FNV A;  4E1Y A;  2WW3 A;  3IAP A;  1PX4 A;  1JYN A;  3VDA A; 
#chains in the Genus database with same CATH topology
 2RDY A;  5EAS A;  1N23 A;  3K25 A;  3BUP A;  2CWU A;  1N4S B;  3E7J A;  4OK2 A;  4K35 A;  3QSP A;  1N22 A;  1G87 A;  1AV4 A;  1UI7 A;  3T2O A;  1FT1 B;  3T0A A;  3MPH A;  1I8Q A;  3Q7F B;  1X9D A;  4KFE A;  1KWF A;  1L7J A;  2A8Z A;  1QAL A;  5IL8 A;  1KFG A;  2E24 A;  1NXC A;  1IA6 A;  3NNB A;  5FO7 B;  3X40 A;  2HTB A;  2FV0 A;  4GTQ B;  1HCU A;  1HXA A;  4WVC A;  1H37 A;  5DGQ A;  3E1F 1;  2WMH A;  2H6I B;  3K5T A;  5GZK A;  1W5Z A;  2AHF A;  1JOV A;  4C1S A;  2JJB A;  4QT9 A;  1HTY A;  2V8J A;  1NS8 A;  5IK9 A;  1QAK A;  1FBO A;  4GAX A;  1NSU A;  2ZZR A;  2CFG A;  1LD7 B;  3VD5 A;  4D6H A;  1H13 A;  2JKP A;  1NSM A;  4D8O A;  1V7V A;  5E2J A;  3QRY A;  1QAZ A;  5ILK A;  1TN6 B;  3M7L A;  2WMK A;  2JKE A;  4ZG8 A;  3T2Q A;  2E2U A;  3ECQ A;  4J5T A;  2CFL A;  3RX5 A;  2E2T A;  1H12 A;  2DRR A;  3I3B A;  3QFY A;  3VW5 A;  4UFC A;  2F7Q A;  2G02 A;  2WCO A;  4AYQ A;  4D4B A;  1LF6 A;  4LIX A;  4BTY A;  3H3K A;  3M7B A;  2F7R A;  3DYM A;  1GXM A;  4D6F A;  2CFW A;  2WW1 A;  3VDC A;  4OK4 A;  1N4R B;  3S4C A;  3DDF A;  1EGU A;  1X1J A;  2Z07 A;  5DGR A;  5E1Q A;  4FNQ A;  1LUR A;  4GTV B;  3M01 A;  1GAI A;  1IVW A;  1NI1 B;  1OAC A;  3VSM A;  2WMG A;  3KII A;  1CB8 A;  1US1 A;  4DUW A;  1GHQ A;  1MZC B;  3M00 A;  3QPF A;  1W2Z A;  1HMU A;  1WMO A;  3EJP A;  4GTO B;  1NSS A;  4DUV A;  2B39 A;  1O7D D;  2CQS A;  5EAU A;  1QWU A;  1O1S B;  2YFO A;  1G6I A;  3T0B A;  2XN0 A;  1AGM A;  3H7L A;  1LF9 A;  1KSC A;  1N4Q B;  1N7Q A;  3TF4 A;  4WU0 A;  2JF4 A;  3QDE A;  3A24 A;  3D5S A;  1HN0 A;  1XW2 A;  1TNZ B;  1IS9 A;  4KKI A;  3BUD A;  2XFG A;  3N0G A;  1PU4 A;  2D5J A;  2W0Q A;  1JZ2 A;  1GAH A;  3ACT A;  1MMY A;  4BZE A;  2F7P A;  4TF4 A;  2DRQ A;  1JZ6 A;  2BRP A;  1HXK A;  3DSS B;  1O1T B;  1N1B A;  3D50 A;  3W5N A;  1F4H A;  3LOY A;  1HM2 A;  4BZF A;  2WII B;  5IL3 A;  3W5M A;  1KRF A;  3J7H A;  1G9J A;  2VN7 A;  4OZW A;  3X17 A;  5M7I A;  5ILY A;  1TQS A;  2YX9 A;  1N9A B;  1V7X A;  3HXD B;  3SAE A;  3VDB A;  2WDA A;  1SNZ A;  1WMP A;  1WZZ A;  3D5R A;  1IA7 A;  3SXX A;  4FXG B;  3KSL B;  5GW7 A;  3D4Y A;  3QR8 A;  3IAP A;  1F9G A;  2WY8 A;  1WU5 A;  4AQ0 A;  3HXE B;  1IVX A;  1AVL A;  4DI5 A;  5A1A A;  3GT5 A;  2ZBL A;  4RNL A;  1LOH A;  1PS3 A;  3NJV A;  4ONT A;  1D8D B;  2FYV A;  1N7P A;  1L2A A;  2GH4 A;  2D1W A;  2XWJ B;  3E6U A;  3HXC B;  3EUV B;  4V1S A;  4BTW A;  3NJX A;  3DX3 A;  3M78 A;  1TN7 B;  3GZK A;  3RX7 A;  4AYO A;  5ILZ A;  3BVV A;  3NBJ A;  2BED B;  3NBB A;  3Q1N A;  3HXB B;  4XUV A;  1F4A A;  4F10 A;  2NVP A;  1NS4 A;  1MMU A;  3S4B A;  1YGA A;  1W6J A;  2WVX B;  3BGA A;  3WKG A;  3E73 A;  1GA2 A;  1NL4 B;  1G9G A;  2QNO A;  3W7T A;  3VSN A;  3HII A;  4AYP A;  3SFY B;  2CG1 A;  2JKA A;  4ZH5 A;  2IEJ B;  2WYN A;  4Q2B A;  3EJQ A;  1RKY A;  3ANK A;  1NS2 A;  2F7O A;  2OQE C;  4FXK B;  3D51 A;  3W7X A;  2OOV C;  3DPY B;  3M75 A;  4D1I A;  1IVV A;  1O6H A;  2HTA A;  2BRV X;  2OW7 A;  2WVY A;  1H54 A;  2H6G B;  3E34 B;  1JZ3 A;  3P5R A;  1FO3 A;  1IQX A;  1GLM A;  2F0Y B;  2OQE A;  4D6C A;  2XN2 A;  3T0D A;  2WIN B;  2F1A A;  1NS7 A;  3S4D A;  3EJT A;  3WKF A;  5FO9 B;  4D94 A;  1N4P B;  1HMW A;  1FP3 A;  3PYA A;  3OBA A;  1SA5 B;  3I3D A;  4FNT A;  2WZS A;  4CE7 A;  3TY1 A;  2BB5 A;  2C10 A;  2XN1 A;  3HXF B;  2F18 A;  1DL2 A;  3WKI A;  1Z45 A;  1SII A;  3X3Y A;  5IM1 A;  1R34 A;  4BTX A;  3G4F A;  3WVF A;  4BZH A;  3PZ2 B;  1CEM A;  1LVN A;  4YCR A;  3RSY A;  4FNU A;  3BVW A;  2WOF A;  1OJO A;  5CD2 A;  3WIW A;  2FUQ A;  1TNY B;  3SDV A;  3IAQ A;  1JZ7 A;  5IK6 A;  1GSZ A;  2V3N A;  2BRW A;  1D6Z A;  1FPP B;  1JCQ B;  3M76 A;  4WVB A;  1RWC A;  3D3I A;  3M72 A;  4NEI A;  3BVX A;  2OW6 A;  1KRE A;  1JZ8 A;  1N21 A;  3DX0 A;  1OJP A;  3DX2 A;  3OXU A;  1RWG A;  3WKH A;  4Z4L A;  1N7N A;  4ZRQ A;  5MEH A;  1QSJ A;  4GTT B;  1D8E B;  1X1I A;  1J0M A;  2WMJ A;  1F1S A;  2KXS A;  3W7W A;  4Z4J A;  1TNB B;  2R2L B;  3I3E A;  3VD4 A;  2I07 B;  3EQA A;  3PZ3 B;  1HM3 A;  1SQC A;  3DYP A;  4D6J A;  5KBP A;  2FUT A;  5DHI A;  3MV1 1;  4D4C A;  4F13 A;  3M7E A;  1TQW A;  1QQF A;  3H2W A;  3K7X A;  3M02 A;  1O5M B;  3DST B;  3CIH A;  1UT9 A;  1DOG A;  2FBA A;  3RX8 A;  1HXG A;  1KZP B;  1S64 B;  1N9E A;  2CFK A;  3T09 A;  4EV5 A;  4GTR B;  5JPN B;  1N20 A;  3NFV A;  2E22 A;  1WMN A;  1LD8 B;  4KTR A;  1R76 A;  4LNB B;  1O79 A;  2WO0 A;  1K1X A;  4KKJ A;  4MMI A;  3X41 A;  3SFX B;  2WMI A;  4DOD A;  1QWN A;  1ULV A;  3E30 B;  2D73 A;  4D6D A;  2CWV A;  5DHK A;  1F9O A;  3PYB A;  4MMH A;  1NC5 A;  4TTG A;  4BOK A;  1FO2 A;  4DUX A;  2EAC A;  3S9V A;  2CWT A;  2ZL8 A;  1FBW A;  2H6F B;  1LTX B;  3M73 A;  3QWT A;  1MMZ A;  3WA2 X;  2ZQ0 A;  3QFZ A;  1C82 A;  3T33 A;  3DSV B;  3BVU A;  5KKB A;  2FUZ A;  4L0G A;  4D4A A;  2ZIR B;  1HZF A;  2AFA A;  3HI7 A;  1UI8 A;  1YQ2 A;  4DLO A;  1V5D A;  3EU5 B;  1WU4 A;  4GTM B;  3CZN A;  3N9H A;  3RRS A;  3EJR A;  3M74 A;  3E33 B;  4FNR A;  3KLS A;  5IKH A;  4D72 A;  5CZL A;  3WFA A;  3ACS A;  2B4F A;  1DCE B;  1GXO A;  1JCS B;  5C05 A;  5ILD A;  2JG0 A;  1R33 A;  3DSU B;  4CJ0 A;  4D71 A;  4MU9 A;  2FV1 A;  4FJQ A;  5JMF A;  1JS4 A;  3DCD A;  1TN8 B;  4V1R A;  3QG0 A;  2KXR A;  3MWX A;  3N0F A;  3QT9 A;  1H3A A;  1KS8 A;  3A3V A;  1PX4 A;  1NSV A;  2WMF A;  1AVK A;  1O6Q A;  4L9P B;  1NSR A;  1TQU A;  3DX1 A;  4GTS B;  1W4N A;  5FO8 B;  2PNC A;  1SIH A;  2Y73 A;  3DRA B;  3E80 A;  1KKT A;  3Q75 B;  2ZXQ A;  2GZ6 A;  4D4D A;  3DX4 A;  1XWT A;  1JZ4 A;  3GLY A;  5FOB B;  2A73 B;  1W3Y A;  1NSX A;  2YIK A;  4TXT A;  3DYO A;  2CFD A;  1JRQ A;  2OOV A;  1NSZ A;  3C72 B;  3F59 A;  1RWH A;  2WY7 A;  3EU8 A;  2WW0 A;  1N24 A;  1RWF A;  3CV5 A;  4BZG A;  1RWA A;  2WW2 A;  3CZJ A;  2CIQ A;  1OJN A;  1TNU B;  3DSW B;  2F6D A;  5CA3 A;  3M77 A;  3UD2 A;  1DP0 A;  1FAE A;  1W6C A;  1D6Y A;  1H3B A;  2RI9 A;  1RJO A;  3X3Z A;  3NRE A;  4DOE A;  1JYV A;  1SO0 A;  2V8K A;  3W7U A;  2GOX A;  3BUQ A;  3SDQ A;  1AYX A;  4D6E A;  1TXK A;  1HX9 A;  1QX1 A;  2PN5 A;  3MV0 1;  1HV6 A;  3OS7 A;  3M71 A;  3SDU A;  2BT3 A;  2CG0 A;  2YFN A;  3OED A;  1N7R A;  4D1J A;  4GL3 A;  4D6G A;  3ON6 A;  4FNV A;  1WU6 A;  3ANJ A;  2RGK A;  4E1Y A;  1TQV A;  2D8L A;  4WVA A;  1IU7 A;  1JYN A;  3DSX B;  1L1Y A;  1V5C A;  3T0U A;  3DEC A;  1LXM A;  3PQI A;  1LXK A;  2WOH A;  3KBU C;  4JJJ A;  1UMP A;  3RJ3 A;  1D6U A;  5ILI A;  2DRS A;  5ILH A;  2C11 A;  1TF4 A;  1X1H A;  3BUB A;  3SX1 A;  1TQT A;  1PX3 A;  1QAF A;  1W6G A;  3WIR A;  2XQW A;  2EAB A;  3QXQ A;  4KFF A;  1N7O A;  2PMV A;  2VN4 A;  1XWQ A;  3AFL A;  4AYR A;  3PZ1 B;  2ALW A;  3X42 A;  3Q7A B;  3UD1 A;  3AMO A;  4OJZ A;  1DYU A;  1X81 B;  1HN1 A;  1H35 A;  1FMI A;  4L6X A;  1VD5 A;  4FUS A;  2WYH A;  3BLC A;  4FNP A;  1HWW A;  1N1Z A;  5AGD A;  4CJ1 A;  2WGQ A;  3T08 A;  4ZH1 A;  2DRO A;  3P5P A;  1FT2 B;  1RW9 A;  2ONG A;  4EL8 A;  3WC3 A;  5ILJ A;  3ALA A;  1F9D A;  4MBG B;  1K1Y A;  3PMM A;  2WYI A;  4FNS A;  3AMO B;  1GXN A;  5GY3 A;  4KTP A;  1NS0 A;  3X3X A;  1L7K A;  3IMH A;  2CIR A;  1H39 A;  3SEP A;  2NOJ A;  3PZ4 B;  1W7C A;  2BB6 A;  3G4D A;  1H36 A;  2XHN A;  5IK0 A;  2F1B A;  2G0D A;  3G6J B;  3KSQ B;  2V8I A;  3CU7 A;  5EAT A;  1KSI A;  3E32 B;  1MN0 A;  4BOJ A;  3MUY 1;  2ZIS B;  4ZRP A;  4D6I A;  1MMX A;  3KN4 A;  2BBC A;  3QT3 A;  2RI8 A;  1JYX A;  3VD9 A;  3PGB A;  3LZ9 A;  4OZV A;  4M76 A;  1RQ5 A;  1NKG A;  3D52 A;  1C3D A;  3VXD A;  4DLQ A;  2X03 A;  3VD3 A;  1S63 B;  4K3A A;  2WMI B;  1TU5 A;  4LNV A;  1JZ5 A;  4EV2 A;  1QBQ B;  3E37 B;  5JPM B;  2V3P A;  3Q73 B;  1TNO B;  4YDE B;  3MI6 A;  3HIG A;  1JYW A;  1CLC A;  3EJU A;  1H14 A;  1O6R A;  3A0O A;  1J0N A;  3SQC A;  3BVT A;  3D4Z A;  3OB8 A;  1N95 B;  3EJS A;  3WA3 A;  1JCR B;  1K72 A;  3SDR A;  1SPU A;  3REN A;  2E2V A;  3ANI A;  4YDO B;  2WVZ A;  2J5C A;  1W6K A;  3EZ8 A;  2AHG A;  3S4A A;  4LNG B;  2OKX A;  3Q79 B;  1FCE A;  2EAD A;  3KQ4 A;  3LVT A;  2SQC A;  3AFJ A;  3WIQ A;  2ONH A;  3KBT C;  2H6H B;  2WVX A;  3T2P A;  3DDG A;  1UG9 A;  2Q1F A;  3P2C A;  1A2V A;  3K11 A;  3QXF A;  1V7W A;  4EHM B;  1EKM A;  2CIS A;  3SDT A;  1N94 B;  1HXC A;  2EAE A;  1H3C A;  3BLB A;  2P0V A;  1KZO B;  2XSG A;  1KSD A;  3BUI A;  4GTP B;  3U7V A;  5IKA A;  3M7C A;  1IQY A;  1O1R B;  4RNQ A;  1K1W A;  3MUZ 1;  3BS6 A;  1IVU A;  4Q88 A;  5JMD A;  1OJM A;  3Q78 B;  3CZS A;  1SA4 B;  3W7S A;  3VD7 A;  5M7Y A;  4KFD A;  3WUX A;  2Y74 A;  2WW3 A;  2XWB B;  2CQT A;  3VDA A; 
#chains in the Genus database with same CATH homology
 1F9G A;  3DEC A;  1LXM A;  3T09 A;  1LXK A;  4AQ0 A;  3K25 A;  5A1A A;  4RNL A;  1LOH A;  3E7J A;  3NFV A;  4OK2 A;  2E22 A;  3NJV A;  1N7P A;  3T2O A;  1X1H A;  3T0A A;  1PX3 A;  1I8Q A;  3NJX A;  1L7J A;  1N7O A;  3AFL A;  1K1X A;  4MMI A;  3Q1N A;  2E24 A;  3NNB A;  2WMI A;  1F4A A;  1ULV A;  2HTB A;  4F10 A;  2D73 A;  4OJZ A;  4D6D A;  1HN1 A;  1NS4 A;  1MMU A;  1YGA A;  3E1F 1;  2WMH A;  2WVX B;  4MMH A;  3BGA A;  4TTG A;  4DUX A;  3BLC A;  1JOV A;  3T08 A;  3VSN A;  1RW9 A;  1NS8 A;  2JKA A;  1NSU A;  1K1Y A;  1MMZ A;  3VD5 A;  4D6H A;  2JKP A;  2ZQ0 A;  1NSM A;  1C82 A;  1NS0 A;  1NS2 A;  1L7K A;  3IMH A;  2CIR A;  1QAZ A;  3SEP A;  2WMK A;  2HTA A;  2BRV X;  2JKE A;  1YQ2 A;  2WVY A;  2XHN A;  3ECQ A;  3T2Q A;  4J5T A;  1JZ3 A;  3I3B A;  1MN0 A;  4D6C A;  3T0D A;  3MUY 1;  2WCO A;  1NS7 A;  4D6I A;  1MMX A;  3WFA A;  4D72 A;  1LF6 A;  3DYM A;  4D6F A;  2WW1 A;  3VDC A;  4OK4 A;  1EGU A;  1HMW A;  4D71 A;  3OBA A;  1X1J A;  3I3D A;  5E1Q A;  5JMF A;  1JYX A;  1LUR A;  3VD9 A;  4OZV A;  2WZS A;  3DCD A;  1NKG A;  3TY1 A;  3VSM A;  2WMG A;  3MWX A;  2X03 A;  3VD3 A;  1CB8 A;  4DUW A;  2WMI B;  1Z45 A;  1HMU A;  1JZ5 A;  1NSV A;  2WMF A;  1NSS A;  1NSR A;  3T2P A;  3WVF A;  4BZH A;  4DUV A;  1JYW A;  3E80 A;  2ZXQ A;  3OB8 A;  3A0O A;  3T0B A;  1J0N A;  1LF9 A;  1N7Q A;  1JZ4 A;  1OJO A;  1W3Y A;  1NSX A;  2FUQ A;  3A24 A;  3DYO A;  1HN0 A;  2WVZ A;  3IAQ A;  1NSZ A;  1JZ7 A;  1RWH A;  2WW0 A;  1JZ2 A;  4BZG A;  1RWF A;  1RWA A;  2WW2 A;  2BRW A;  3CZJ A;  1MMY A;  1OJN A;  2CIQ A;  4BZE A;  1JZ6 A;  2BRP A;  1RWC A;  1DP0 A;  4NEI A;  2WVX A;  1JZ8 A;  1OJP A;  1F4H A;  3NRE A;  1UG9 A;  1RWG A;  1HM2 A;  4BZF A;  1SO0 A;  1N7N A;  2Q1F A;  1JYV A;  3J7H A;  2CIS A;  1X1I A;  1J0M A;  4OZW A;  2WMJ A;  1F1S A;  4D6E A;  2XSG A;  3I3E A;  3VD4 A;  1TXK A;  3VDB A;  2WDA A;  1SNZ A;  1HM3 A;  3MV0 1;  3DYP A;  1HV6 A;  3OS7 A;  4D6J A;  1K1W A;  3MUZ 1;  3BS6 A;  2FUT A;  3MV1 1;  1N7R A;  4F13 A;  5JMD A;  1OJM A;  4D6G A;  3VD7 A;  4FNV A;  4E1Y A;  2WW3 A;  3IAP A;  1PX4 A;  1JYN A;  3VDA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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