1HMWA

Active site of chondroitinase ac lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis
Total Genus 236
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
236
sequence length
674
structure length
674
Chain Sequence
GTAELIMKRVMLDLKKPLRNMDKVAEKNLNTLQPDGSWKDVPYKDDAMTNWLPNNHLLQLETIIQAYIEKDSHYYGDDKVFDQISKAFKYWYDSDPKSRNWWHNEIATPQALGEMLILMRYGKKPLDEALVHKLTERMKRGEPEKKTGANKTDIALHYFYRALLTSDEALLSFAVKELFYPVQFVHYEEGLQYDYSYLQHGPQLQISSYGAVFITGVLKLANYVRDTPYALSTEKLAIFSKYYRDSYLKAIRGSYMDFNVEGRGVSRPDILNKKAEKKRLLVAKMIDLKHTEEWADAIARTDSTVAAGYKIEPYHHQFWNGDYVQHLRPAYSFNVRMVSKRTRRSESGNKENLLGRYLSDGATNIQLRGPEYYNIMPVWEWDKIPGITSRDYLTDRPLTKLWGEQGSNDFAGGVSDGVYGASAYALDYDSLQAKKAWFFFDKEIVCLGAGINSNAPENITTTLNQSWLNGPVISTAGKTGRGKITTFKAQGQFWLLHDAIGYYFPEGANLSLSTQSQKGNWFHINNSHSKDEVSGDVFKLWINHGARPENAQYAYIVLPGINKPEEIKKYNGTAPKVLANTNQLQAVYHQQLDMVQAIFYTAGKLSVAGIEIETDKPCAVLIKHINGKQVIWAADPLQKEKTAVLSIRDLKTGKTNRVKIDFPQQEFAGATVEL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis.
pubmed doi rcsb
source organism Pedobacter heparinus
molecule tags Lyase
molecule keywords CHONDROITINASE AC
total genus 236
structure length 674
sequence length 674
ec nomenclature ec 4.2.2.5: Chondroitin AC lyase.
pdb deposition date 2000-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1hmwA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1hmwA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1hmwA02
1OJNA 4OZVA 4D6JA 1YGAA 3IMHA 1RWCA 1HM2A 1C82A 3BGAA 1EGUA 1DP0A 3OB8A 4E1YA 3VDCA 1N7PA 2XSGA 3DYPA 1YQ2A 1JYNA 4D6IA 1MMXA 2ZQ0A 2CIQA 1HMWA 1NSXA 4D6CA 1SO0A 3T2OA 2WZSA 1LOHA 3NJVA 2HTAA 1JZ4A 1JYVA 3VD5A 5JMDA 3AFLA 3T0AA 1X1IA 1N7OA 1F4HA 3NFVA 2WCOA 1NSMA 3MUY1 1HV6A 1JZ8A 1L7KA 4DUXA 3T2QA 1LXMA 1K1YA 1N7QA 2FUQA 1HM3A 1RWGA 2ZXQA 3T0BA 4BZEA 1JZ7A 1QAZA 1JYXA 3WFAA 2WMKA 1MMZA 3VD4A 3VSNA 2WVZA 3SEPA 1OJMA 1NKGA 2FUTA 2XHNA 2CIRA 3J7HA 1I8QA 4OK2A 4D6FA 1JZ3A 2CISA 1N7NA 1NS0A 1J0MA 3OS7A 4OJZA 1LF6A 3I3EA 3I3BA 2E22A 1NS4A 2Q1FA 2WMIA 4OK4A 1NSUA 1UG9A 2WW0A 4F13A 3VD3A 2WW3A 3DECA 1L7JA 3NREA 2WMJA 3Q1NA 3MWXA 1ULVA 1F4AA 3E80A 1MN0A 1PX3A 3T2PA 2BRWA 1J0NA 3I3DA 1JZ2A 1JOVA 2BRVX 1CB8A 1K1WA 1MMYA 1TXKA 3VD9A 1NS8A 4D72A 4BZFA 3MUZ1 1N7RA 1SNZA 1LURA 2D73A 3T08A 4OZWA 1X1HA 4D6EA 2JKEA 1NSRA 1RWFA 1LXKA 3IAQA 3VDAA 3T0DA 3OBAA 2WVXA 1LF9A 3MV01 2WMFA 4DUWA 4AQ0A 2WVXB 3CZJA 5E1QA 5A1AA 2BRPA 3E1F1 2E24A 1NSVA 4D6DA 2WW1A 1RWHA 3VSMA 4BZHA 2JKPA 1OJOA 1JYWA 1RWAA 1HN0A 4NEIA 2X03A 3DYMA 3A24A 1HMUA 2WVYA 1HN1A 1F1SA 1X1JA 2HTBA 4FNVA 4BZGA 1PX4A 4MMIA 2WMHA 3ECQA 3VD7A 1JZ5A 3VDBA 3T09A 2WMIB 4D71A 3MV11 4F10A 1OJPA 4RNLA 3DYOA 1NS2A 4D6GA 3DCDA 1NS7A 2WW2A 1JZ6A 1W3YA 3NJXA 1NSZA 4MMHA 2JKAA 1K1XA 3IAPA 1MMUA 3NNBA 1RW9A 1NSSA 3A0OA 4TTGA 3K25A 4DUVA 1F9GA 4D6HA 1Z45A 2WDAA 2WMGA 3E7JA 5JMFA
chains in the Genus database with same CATH superfamily
4ONTA 4D6JA 1YGAA 3RX8A 2XN0A 5IKHA 1DP0A 1N9EA 5GW7A 4DLQA 2XSGA 1K72A 3QRYA 2CIQA 3H7LA 4C1SA 1O6QA 2CFDA 3NJVA 3PZ1B 5IK0A 1KREA 2XWJB 3EJPA 2F7OA 3M01A 2CWTA 2H6HB 2F7RA 3SDQA 2FYVA 1NSMA 1JZ8A 3G4FA 3E73A 4WU0A 2Y73A 1GXOA 3BVXA 1FO3A 3EZ8A 1KZPB 3SFYB 1LXMA 1K1YA 3MPHA 4KFDA 1RWGA 3DPYB 3DSXB 3X3XA 3WFAA 1S64B 3PZ3B 4KTRA 1X81B 3EJUA 3G6JB 1OJMA 3QFYA 3RX5A 1N1ZA 3UD2A 4FXKB 3W7WA 2JJBA 1N7NA 1UT9A 1N94B 3AMOA 2EADA 3C72B 1H35A 3HXFB 1NS4A 3SQCA 2Q1FA 1IVWA 3X3ZA 2WW0A 1EKMA 1V7VA 3DX3A 3ON6A 4EHMB 1QAKA 5ILYA 3E33B 1FBWA 5FOBB 3W5NA 1O6HA 2CG0A 3DECA 3WA2X 3NREA 2D5JA 2YX9A 1ULVA 3EUVB 1F4AA 3Q75B 3T2PA 1J0NA 5EAUA 5DGQA 3T33A 1K1WA 3X41A 1N1BA 1LVNA 3E37B 2D73A 4OZWA 4GTQB 5FO7B 3D51A 2AHGA 1NSRA 1N9AB 1RWFA 1WU6A 3VDAA 1LF9A 4DUWA 1HXGA 1O7DD 3CZJA 1IVVA 2BRPA 5GY3A 1DOGA 1WMOA 1TQSA 2W0QA 1H54A 4D94A 3GT5A 3BUPA 4EL8A 3ACTA 1RWHA 3VSMA 4BOKA 1JYWA 2E2TA 4TXTA 2WYIA 1L2AA 1IA6A 3M75A 3ACSA 4ZRPA 5EASA 1TQUA 4FJQA 1HN1A 1F1SA 2F1AA 2ZZRA 2PNCA 4BZGA 1KSDA 5EATA 1HXKA 1AVLA 3BUIA 1GXNA 2JG0A 1F9DA 1D6YA 1H37A 3WIRA 2OW6A 3T09A 3LOYA 2WMIB 1H3CA 1DL2A 2OKXA 1HTYA 2ONGA 3DYOA 4RNLA 3X42A 3KIIA 3DRAB 3W7SA 3F59A 1TQWA 2B4FA 2ZBLA 4FNQA 4BTXA 4Z4LA 5KKBA 1TNYB 1RW9A 2EAEA 3DSWB 1NSSA 3NBBA 2OOVA 2H6GB 3SDVA 1F9GA 3KBUC 1L7KA 1HXCA 5IL3A 1OJNA 1HM2A 1C82A 1N23A 3K5TA 1CEMA 1WZZA 3A3VA 3TY1A 1XWQA 5IL8A 1R33A 3AMOB 4AYOA 1RJOA 1TNUB 5M7IA 4D6IA 1MMXA 3S4CA 4D4BA 4CJ0A 1QALA 1SIHA 2WZSA 3M77A 2RGKA 1JYVA 1JCSB 2BT3A 3AFLA 3X3YA 1X1IA 1N22A 3PYBA 1O6RA 1H3BA 2WCOA 4L9PB 2GZ6A 3S9VA 1AVKA 1DYUA 1D8EB 3AFJA 1SPUA 3HI7A 3T2QA 4EV2A 1HM3A 2EACA 2F7PA 1H36A 4WVCA 4ZG8A 3T0BA 1QAZA 1V7XA 2EABA 4AYPA 2WMKA 5DHIA 3D4YA 1IVXA 2P0VA 2WVZA 1G9JA 3D4ZA 4LNVA 3PMMA 1JCRB 1NKGA 2DRSA 2FUTA 1G6IA 2CIRA 1KWFA 1O1TB 3E30B 4D6FA 4J5TA 1JZ3A 2CISA 1NS0A 1J0MA 1JCQB 3BUQA 3QFZA 3I3EA 4FNSA 1Z45A 5AGDA 4D1IA 2CFGA 3DDFA 3EU5B 4GTRB 3W7UA 4F13A 1XW2A 1H12A 3QG0A 3VD3A 3DX2A 2WW3A 3CZSA 5JPMB 1L7JA 3EJRA 3KSQB 3Q1NA 3MWXA 3P5RA 1H13A 5DGRA 2WOFA 1MN0A 1PX3A 2F1BA 1JZ2A 1JOVA 1US1A 1QBQB 3Q7AB 2OQEC 1HCUA 3EJSA 1IQXA 3LZ9A 4D72A 4Q88A 3PGBA 4JJJA 4BZFA 1N7RA 1LURA 3T08A 2H6FB 1OACA 2NVPA 1FO2A 1KSCA 3K7XA 2VN4A 4D6EA 2JKEA 2XN2A 4FNPA 5ILZA 3IAQA 3T0DA 3KQ4A 2YIKA 3CV5A 4GTMB 4ZH1A 3CU7A 3UD1A 1WMPA 2ZIRB 5A1AA 2V3PA 1GA2A 3WKIA 3SAEA 3K11A 3PQIA 3E1F1 1NSVA 4D6DA 1XWTA 2C11A 4ZRQA 1GAIA 4D1JA 4AYQA 2JKPA 1IA7A 2F18A 4MBGB 2X03A 2V8JA 4GTTB 3WUXA 2HTBA 3D5RA 3SFXB 4MMIA 3EJQA 1FT1B 5CD2A 1PS3A 1AV4A 3VD7A 3VDBA 2CG1A 2OQEA 4D71A 1OJPA 2V8KA 4GTOB 3DCDA 5CZLA 1VD5A 3NJXA 1NSZA 2Z07A 5CA3A 2JF4A 2C10A 1K1XA 1TNBB 5ILDA 3IAPA 3A0OA 2CFKA 1IS9A 1WU4A 4D6HA 3E7JA 1HN0A 2WVXA 3M78A 2WYNA 4OZVA 3IMHA 1W6GA 1RWCA 2DRQA 1W6JA 3OXUA 1N21A 3OB8A 2BBCA 3X17A 4E1YA 1V5CA 1N7PA 2GH4A 3CIHA 1G9GA 3DYPA 1JYNA 1WMNA 2PMVA 1HMWA 2YFOA 2R2LB 4D6CA 1O79A 3SDUA 1NXCA 1SO0A 1GSZA 1LOHA 2HTAA 1JZ4A 3M7LA 3VD5A 1W6CA 3PZ4B 1HWWA 1D8DB 1KFGA 3HIGA 1N7OA 4BOJA 4DI5A 3DSTB 2AHFA 1HV6A 3QXQA 1H3AA 3VW5A 3QXFA 3M7CA 1GXMA 1R34A 4MU9A 4TF4A 4DUXA 1PU4A 4Q2BA 4WVAA 1N7QA 1KKTA 1AGMA 5ILJA 2ZXQA 4BZEA 2NOJA 2ZISB 2B39A 1F9OA 4FUSA 1N4RB 3QPFA 3VSNA 2WIIB 3SEPA 1CLCA 4LIXA 5ILKA 2A8ZA 2I07B 1FT2B 1UI8A 1QX1A 1MZCB 1O1RB 4OK2A 5M7YA 4YDOB 1DCEB 4V1SA 3OS7A 3M74A 1FAEA 4OJZA 3KN4A 3EQAA 4LNGB 1C3DA 2E2UA 1GAHA 1LF6A 3QT3A 1JRQA 3I3BA 1QSJA 3DX4A 1LD7B 1UG9A 4KTPA 1NSUA 2D1WA 3BLBA 1O1SB 4L6XA 1QWUA 5IM1A 4DLOA 3P5PA 1W7CA 3EJTA 3ANIA 1GLMA 1RKYA 3M7EA 3LVTA 1TN6B 3I3DA 4K35A 1G87A 2BRVX 2GOXA 3HXCB 1MMYA 1TXKA 1SA5B 3VD9A 1NC5A 3D3IA 4YDEB 5C05A 5IKAA 2FUZA 2WYHA 2RDYA 1X1HA 3BVWA 3PYAA 3BVTA 1W2ZA 3N0FA 3OBAA 4QT9A 3MV01 3S4DA 3BVVA 1AYXA 2D8LA 5GZKA 4AQ0A 2WVXB 3M76A 3SX1A 1NL4B 1SA4B 2F0YB 2FV0A 1L1YA 2WO0A 2E24A 2G0DA 3WKHA 4M76A 4DODA 4BZHA 3Q73B 1OJOA 3M00A 2OOVC 1RWAA 3DYMA 3A24A 1HMUA 1TN7B 2WVYA 4FNUA 1R76A 1N24A 2WINB 4FNVA 3U7VA 3E32B 3QSPA 1PX4A 3BLCA 1D6ZA 4BTYA 3RSYA 3SDTA 5FO8B 1NI1B 3WC3A 2WMHA 3BVUA 2DROA 1TQVA 3DX0A 4D4AA 4F10A 3DSSB 3S4AA 4FNTA 3S4BA 1A2VA 4D6GA 1NS7A 3OEDA 2WW2A 4GAXA 4UFCA 4MMHA 2JKAA 2DRRA 4FNRA 3M73A 1X9DA 5E2JA 2E2VA 4TTGA 1FMIA 1QQFA 1FPPB 1N4SB 4ZH5A 3K25A 3G4DA 3ANKA 2WDAA 3T0AA 1TF4A 2WY7A 3KBTC 3Q78B 1S63B 2BB5A 3WIQA 3BGAA 1O5MB 1EGUA 4LNBB 4FXGB 3VDCA 2J5CA 3P2CA 1YQ2A 2ZQ0A 2ALWA 1NSXA 4KKJA 3E6UA 4D4CA 4DOEA 3T2OA 2OW7A 5DHKA 5JPNB 5JMDA 4Z4JA 1TNOB 1FBOA 3HXEB 1SIIA 5ILHA 1W4NA 3M72A 3KSLB 1F4HA 3WVFA 3W7TA 2XN1A 4YCRA 3NFVA 3MUY1 1FP3A 3WKGA 4KFEA 2SQCA 2FUQA 3BUBA 1KRFA 1N95B 1JZ7A 1RQ5A 1JYXA 1TU5A 5MEHA 2V8IA 3Q7FB 1MMZA 1V7WA 1IU7A 1N4PB 3VD4A 4GTVB 3EU8A 3HIIA 1SQCA 2YFNA 4CE7A 3GZKA 3QWTA 1HX9A 2XHNA 3J7HA 4K3AA 1N4QB 5ILIA 1I8QA 4BTWA 2V3NA 3WA3A 3D50A 2RI8A 3T0UA 2AFAA 3GLYA 4GL3A 3DX1A 1QWNA 3Q79B 2E22A 3WKFA 2XWBB 2XFGA 1LD8B 2KXRA 2WMIA 1H14A 4OK4A 1H39A 4XUVA 3E34B 1IQYA 2WMJA 2CWUA 3WIWA 3HXBB 3DSUB 1D6UA 2CQSA 2QNOA 3E80A 2BRWA 5IK6A 3N0GA 1CB8A 3H3KA 1LTXB 3M02A 4KFFA 1NS8A 3HXDB 3MUZ1 3SDRA 1SNZA 1WU5A 4L0GA 4D4DA 3MI6A 4GTSB 3W7XA 2ZL8A 2WY8A 3RX7A 3ANJA 2CQTA 3RENA 3D5SA 4RNQA 2ONHA 3W5MA 1GHQA 2G02A 1LXKA 3NBJA 4CJ1A 2XQWA 2WMFA 1IVUA 2IEJB 3DSVB 3SXXA 5KBPA 3CZNA 3QT9A 1TQTA 5E1QA 3QDEA 3QR8A 1KS8A 3BS6A 2A73B 2WOHA 2WGQA 2WW1A 1V5DA 4GTPB 2CFWA 3D52A 3BUDA 1KZOB 1W5ZA 1TNZB 5IK9A 2CFLA 3ALAA 2RI9A 3N9HA 4NEIA 1JS4A 1TN8B 1HZFA 1W6KA 2FV1A 5FO9B 1X1JA 2VN7A 1KSIA 3VXDA 2F6DA 3ECQA 1JZ5A 3PZ2B 1UMPA 4AYRA 2CWVA 1QAFA 3MV11 3DDGA 3M71A 1NS2A 1N20A 2FBAA 1W3YA 1UI7A 1JZ6A 4KKIA 4D8OA 1FCEA 2PN5A 4V1RA 3H2WA 2H6IB 1MMUA 3NNBA 3X40A 2KXSA 3TF4A 2F7QA 2Y74A 3RRSA 1HXAA 3M7BA 4WVBA 3RJ3A 3KLSA 4DUVA 2WMGA 2BEDB 4EV5A 5JMFA 2BB6A
chains in the Genus database with same CATH topology
1OJNA 4OZVA 4D6JA 1YGAA 3IMHA 1RWCA 1HM2A 1C82A 3BGAA 1EGUA 1DP0A 3OB8A 4E1YA 3TY1A 3VDCA 1N7PA 2XSGA 3DYPA 1YQ2A 1JYNA 4D6IA 1MMXA 2ZQ0A 2CIQA 1HMWA 1NSXA 4D6CA 1SO0A 3T2OA 2WZSA 1LOHA 3NJVA 2HTAA 1JZ4A 1JYVA 3VD5A 5JMDA 3AFLA 3T0AA 1X1IA 1N7OA 1F4HA 3WVFA 3NFVA 2WCOA 1NSMA 3MUY1 1HV6A 1JZ8A 1L7KA 4DUXA 3T2QA 1LXMA 1K1YA 1N7QA 2FUQA 1HM3A 1RWGA 2ZXQA 3T0BA 4BZEA 1JZ7A 1QAZA 1JYXA 3WFAA 2WMKA 1MMZA 3VD4A 3VSNA 2WVZA 3SEPA 1OJMA 1NKGA 2FUTA 2XHNA 2CIRA 3J7HA 1I8QA 4OK2A 4D6FA 4J5TA 1JZ3A 2CISA 1N7NA 1NS0A 1J0MA 3OS7A 4OJZA 1LF6A 3I3EA 3I3BA 2E22A 1NS4A 2Q1FA 2WMIA 4OK4A 1NSUA 1UG9A 2WW0A 4F13A 3VD3A 2WW3A 3DECA 1L7JA 3NREA 2WMJA 3Q1NA 3MWXA 1ULVA 1F4AA 3E80A 1MN0A 1PX3A 3T2PA 2BRWA 1J0NA 3I3DA 1JZ2A 1JOVA 2BRVX 1CB8A 1K1WA 1MMYA 1TXKA 3VD9A 1NS8A 4D72A 4BZFA 3MUZ1 1N7RA 1SNZA 1LURA 2D73A 3T08A 4OZWA 1X1HA 4D6EA 2JKEA 1NSRA 1RWFA 1LXKA 3IAQA 3VDAA 3T0DA 3OBAA 2WVXA 1LF9A 3MV01 2WMFA 4DUWA 4AQ0A 2WVXB 3CZJA 5E1QA 5A1AA 2BRPA 3BS6A 3E1F1 2E24A 1NSVA 4D6DA 2WW1A 1RWHA 3VSMA 4BZHA 2JKPA 1OJOA 1JYWA 1RWAA 1HN0A 4NEIA 2X03A 3DYMA 3A24A 1HMUA 2WVYA 1HN1A 1F1SA 1X1JA 2HTBA 4FNVA 4BZGA 1PX4A 4MMIA 3BLCA 2WMHA 3ECQA 3VD7A 1JZ5A 3VDBA 3T09A 2WMIB 4D71A 3MV11 4F10A 1OJPA 4RNLA 3DYOA 1NS2A 4D6GA 3DCDA 1NS7A 2WW2A 1JZ6A 1W3YA 3NJXA 1NSZA 4MMHA 2JKAA 1K1XA 3IAPA 1MMUA 3NNBA 1RW9A 1NSSA 3A0OA 4TTGA 3K25A 4DUVA 1F9GA 4D6HA 1Z45A 2WDAA 2WMGA 3E7JA 5JMFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OJN A;  4OZV A;  4D6J A;  1YGA A;  3IMH A;  1RWC A;  1HM2 A;  1C82 A;  3BGA A;  1EGU A;  1DP0 A;  3OB8 A;  4E1Y A;  3VDC A;  1N7P A;  2XSG A;  3DYP A;  1YQ2 A;  1JYN A;  4D6I A;  1MMX A;  2ZQ0 A;  2CIQ A;  1HMW A;  1NSX A;  4D6C A;  1SO0 A;  3T2O A;  2WZS A;  1LOH A;  3NJV A;  2HTA A;  1JZ4 A;  1JYV A;  3VD5 A;  5JMD A;  3AFL A;  3T0A A;  1X1I A;  1N7O A;  1F4H A;  3NFV A;  2WCO A;  1NSM A;  3MUY 1;  1HV6 A;  1JZ8 A;  1L7K A;  4DUX A;  3T2Q A;  1LXM A;  1K1Y A;  1N7Q A;  2FUQ A;  1HM3 A;  1RWG A;  2ZXQ A;  3T0B A;  4BZE A;  1JZ7 A;  1QAZ A;  1JYX A;  3WFA A;  2WMK A;  1MMZ A;  3VD4 A;  3VSN A;  2WVZ A;  3SEP A;  1OJM A;  1NKG A;  2FUT A;  2XHN A;  2CIR A;  3J7H A;  1I8Q A;  4OK2 A;  4D6F A;  1JZ3 A;  2CIS A;  1N7N A;  1NS0 A;  1J0M A;  3OS7 A;  4OJZ A;  1LF6 A;  3I3E A;  3I3B A;  2E22 A;  1NS4 A;  2Q1F A;  2WMI A;  4OK4 A;  1NSU A;  1UG9 A;  2WW0 A;  4F13 A;  3VD3 A;  2WW3 A;  3DEC A;  1L7J A;  3NRE A;  2WMJ A;  3Q1N A;  3MWX A;  1ULV A;  1F4A A;  3E80 A;  1MN0 A;  1PX3 A;  3T2P A;  2BRW A;  1J0N A;  3I3D A;  1JZ2 A;  1JOV A;  2BRV X;  1CB8 A;  1K1W A;  1MMY A;  1TXK A;  3VD9 A;  1NS8 A;  4D72 A;  4BZF A;  3MUZ 1;  1N7R A;  1SNZ A;  1LUR A;  2D73 A;  3T08 A;  4OZW A;  1X1H A;  4D6E A;  2JKE A;  1NSR A;  1RWF A;  1LXK A;  3IAQ A;  3VDA A;  3T0D A;  3OBA A;  2WVX A;  1LF9 A;  3MV0 1;  2WMF A;  4DUW A;  4AQ0 A;  2WVX B;  3CZJ A;  5E1Q A;  5A1A A;  2BRP A;  3E1F 1;  2E24 A;  1NSV A;  4D6D A;  2WW1 A;  1RWH A;  3VSM A;  4BZH A;  2JKP A;  1OJO A;  1JYW A;  1RWA A;  1HN0 A;  4NEI A;  2X03 A;  3DYM A;  3A24 A;  1HMU A;  2WVY A;  1HN1 A;  1F1S A;  1X1J A;  2HTB A;  4FNV A;  4BZG A;  1PX4 A;  4MMI A;  2WMH A;  3ECQ A;  3VD7 A;  1JZ5 A;  3VDB A;  3T09 A;  2WMI B;  4D71 A;  3MV1 1;  4F10 A;  1OJP A;  4RNL A;  3DYO A;  1NS2 A;  4D6G A;  3DCD A;  1NS7 A;  2WW2 A;  1JZ6 A;  1W3Y A;  3NJX A;  1NSZ A;  4MMH A;  2JKA A;  1K1X A;  3IAP A;  1MMU A;  3NNB A;  1RW9 A;  1NSS A;  3A0O A;  4TTG A;  3K25 A;  4DUV A;  1F9G A;  4D6H A;  1Z45 A;  2WDA A;  2WMG A;  3E7J A;  5JMF A; 
#chains in the Genus database with same CATH topology
 4ONT A;  4D6J A;  1YGA A;  3RX8 A;  2XN0 A;  5IKH A;  1DP0 A;  1N9E A;  5GW7 A;  4DLQ A;  2XSG A;  1K72 A;  3QRY A;  2CIQ A;  3H7L A;  4C1S A;  1O6Q A;  2CFD A;  3NJV A;  3PZ1 B;  5IK0 A;  1KRE A;  2XWJ B;  3EJP A;  2F7O A;  3M01 A;  2CWT A;  2H6H B;  2F7R A;  3SDQ A;  2FYV A;  1NSM A;  1JZ8 A;  3G4F A;  3E73 A;  4WU0 A;  2Y73 A;  1GXO A;  3BVX A;  1FO3 A;  3EZ8 A;  1KZP B;  3SFY B;  1LXM A;  1K1Y A;  3MPH A;  4KFD A;  1RWG A;  3DPY B;  3DSX B;  3X3X A;  3WFA A;  1S64 B;  3PZ3 B;  4KTR A;  1X81 B;  3EJU A;  3G6J B;  1OJM A;  3QFY A;  3RX5 A;  1N1Z A;  3UD2 A;  4FXK B;  3W7W A;  2JJB A;  1N7N A;  1UT9 A;  1N94 B;  3AMO A;  2EAD A;  3C72 B;  1H35 A;  3HXF B;  1NS4 A;  3SQC A;  2Q1F A;  1IVW A;  3X3Z A;  2WW0 A;  1EKM A;  1V7V A;  3DX3 A;  3ON6 A;  4EHM B;  1QAK A;  5ILY A;  3E33 B;  1FBW A;  5FOB B;  3W5N A;  1O6H A;  2CG0 A;  3DEC A;  3WA2 X;  3NRE A;  2D5J A;  2YX9 A;  1ULV A;  3EUV B;  1F4A A;  3Q75 B;  3T2P A;  1J0N A;  5EAU A;  5DGQ A;  3T33 A;  1K1W A;  3X41 A;  1N1B A;  1LVN A;  3E37 B;  2D73 A;  4OZW A;  4GTQ B;  5FO7 B;  3D51 A;  2AHG A;  1NSR A;  1N9A B;  1RWF A;  1WU6 A;  3VDA A;  1LF9 A;  4DUW A;  1HXG A;  1O7D D;  3CZJ A;  1IVV A;  2BRP A;  5GY3 A;  1DOG A;  1WMO A;  1TQS A;  2W0Q A;  1H54 A;  4D94 A;  3GT5 A;  3BUP A;  4EL8 A;  3ACT A;  1RWH A;  3VSM A;  4BOK A;  1JYW A;  2E2T A;  4TXT A;  2WYI A;  1L2A A;  1IA6 A;  3M75 A;  3ACS A;  4ZRP A;  5EAS A;  1TQU A;  4FJQ A;  1HN1 A;  1F1S A;  2F1A A;  2ZZR A;  2PNC A;  4BZG A;  1KSD A;  5EAT A;  1HXK A;  1AVL A;  3BUI A;  1GXN A;  2JG0 A;  1F9D A;  1D6Y A;  1H37 A;  3WIR A;  2OW6 A;  3T09 A;  3LOY A;  2WMI B;  1H3C A;  1DL2 A;  2OKX A;  1HTY A;  2ONG A;  3DYO A;  4RNL A;  3X42 A;  3KII A;  3DRA B;  3W7S A;  3F59 A;  1TQW A;  2B4F A;  2ZBL A;  4FNQ A;  4BTX A;  4Z4L A;  5KKB A;  1TNY B;  1RW9 A;  2EAE A;  3DSW B;  1NSS A;  3NBB A;  2OOV A;  2H6G B;  3SDV A;  1F9G A;  3KBU C;  1L7K A;  1HXC A;  5IL3 A;  1OJN A;  1HM2 A;  1C82 A;  1N23 A;  3K5T A;  1CEM A;  1WZZ A;  3A3V A;  3TY1 A;  1XWQ A;  5IL8 A;  1R33 A;  3AMO B;  4AYO A;  1RJO A;  1TNU B;  5M7I A;  4D6I A;  1MMX A;  3S4C A;  4D4B A;  4CJ0 A;  1QAL A;  1SIH A;  2WZS A;  3M77 A;  2RGK A;  1JYV A;  1JCS B;  2BT3 A;  3AFL A;  3X3Y A;  1X1I A;  1N22 A;  3PYB A;  1O6R A;  1H3B A;  2WCO A;  4L9P B;  2GZ6 A;  3S9V A;  1AVK A;  1DYU A;  1D8E B;  3AFJ A;  1SPU A;  3HI7 A;  3T2Q A;  4EV2 A;  1HM3 A;  2EAC A;  2F7P A;  1H36 A;  4WVC A;  4ZG8 A;  3T0B A;  1QAZ A;  1V7X A;  2EAB A;  4AYP A;  2WMK A;  5DHI A;  3D4Y A;  1IVX A;  2P0V A;  2WVZ A;  1G9J A;  3D4Z A;  4LNV A;  3PMM A;  1JCR B;  1NKG A;  2DRS A;  2FUT A;  1G6I A;  2CIR A;  1KWF A;  1O1T B;  3E30 B;  4D6F A;  4J5T A;  1JZ3 A;  2CIS A;  1NS0 A;  1J0M A;  1JCQ B;  3BUQ A;  3QFZ A;  3I3E A;  4FNS A;  1Z45 A;  5AGD A;  4D1I A;  2CFG A;  3DDF A;  3EU5 B;  4GTR B;  3W7U A;  4F13 A;  1XW2 A;  1H12 A;  3QG0 A;  3VD3 A;  3DX2 A;  2WW3 A;  3CZS A;  5JPM B;  1L7J A;  3EJR A;  3KSQ B;  3Q1N A;  3MWX A;  3P5R A;  1H13 A;  5DGR A;  2WOF A;  1MN0 A;  1PX3 A;  2F1B A;  1JZ2 A;  1JOV A;  1US1 A;  1QBQ B;  3Q7A B;  2OQE C;  1HCU A;  3EJS A;  1IQX A;  3LZ9 A;  4D72 A;  4Q88 A;  3PGB A;  4JJJ A;  4BZF A;  1N7R A;  1LUR A;  3T08 A;  2H6F B;  1OAC A;  2NVP A;  1FO2 A;  1KSC A;  3K7X A;  2VN4 A;  4D6E A;  2JKE A;  2XN2 A;  4FNP A;  5ILZ A;  3IAQ A;  3T0D A;  3KQ4 A;  2YIK A;  3CV5 A;  4GTM B;  4ZH1 A;  3CU7 A;  3UD1 A;  1WMP A;  2ZIR B;  5A1A A;  2V3P A;  1GA2 A;  3WKI A;  3SAE A;  3K11 A;  3PQI A;  3E1F 1;  1NSV A;  4D6D A;  1XWT A;  2C11 A;  4ZRQ A;  1GAI A;  4D1J A;  4AYQ A;  2JKP A;  1IA7 A;  2F18 A;  4MBG B;  2X03 A;  2V8J A;  4GTT B;  3WUX A;  2HTB A;  3D5R A;  3SFX B;  4MMI A;  3EJQ A;  1FT1 B;  5CD2 A;  1PS3 A;  1AV4 A;  3VD7 A;  3VDB A;  2CG1 A;  2OQE A;  4D71 A;  1OJP A;  2V8K A;  4GTO B;  3DCD A;  5CZL A;  1VD5 A;  3NJX A;  1NSZ A;  2Z07 A;  5CA3 A;  2JF4 A;  2C10 A;  1K1X A;  1TNB B;  5ILD A;  3IAP A;  3A0O A;  2CFK A;  1IS9 A;  1WU4 A;  4D6H A;  3E7J A;  1HN0 A;  2WVX A;  3M78 A;  2WYN A;  4OZV A;  3IMH A;  1W6G A;  1RWC A;  2DRQ A;  1W6J A;  3OXU A;  1N21 A;  3OB8 A;  2BBC A;  3X17 A;  4E1Y A;  1V5C A;  1N7P A;  2GH4 A;  3CIH A;  1G9G A;  3DYP A;  1JYN A;  1WMN A;  2PMV A;  1HMW A;  2YFO A;  2R2L B;  4D6C A;  1O79 A;  3SDU A;  1NXC A;  1SO0 A;  1GSZ A;  1LOH A;  2HTA A;  1JZ4 A;  3M7L A;  3VD5 A;  1W6C A;  3PZ4 B;  1HWW A;  1D8D B;  1KFG A;  3HIG A;  1N7O A;  4BOJ A;  4DI5 A;  3DST B;  2AHF A;  1HV6 A;  3QXQ A;  1H3A A;  3VW5 A;  3QXF A;  3M7C A;  1GXM A;  1R34 A;  4MU9 A;  4TF4 A;  4DUX A;  1PU4 A;  4Q2B A;  4WVA A;  1N7Q A;  1KKT A;  1AGM A;  5ILJ A;  2ZXQ A;  4BZE A;  2NOJ A;  2ZIS B;  2B39 A;  1F9O A;  4FUS A;  1N4R B;  3QPF A;  3VSN A;  2WII B;  3SEP A;  1CLC A;  4LIX A;  5ILK A;  2A8Z A;  2I07 B;  1FT2 B;  1UI8 A;  1QX1 A;  1MZC B;  1O1R B;  4OK2 A;  5M7Y A;  4YDO B;  1DCE B;  4V1S A;  3OS7 A;  3M74 A;  1FAE A;  4OJZ A;  3KN4 A;  3EQA A;  4LNG B;  1C3D A;  2E2U A;  1GAH A;  1LF6 A;  3QT3 A;  1JRQ A;  3I3B A;  1QSJ A;  3DX4 A;  1LD7 B;  1UG9 A;  4KTP A;  1NSU A;  2D1W A;  3BLB A;  1O1S B;  4L6X A;  1QWU A;  5IM1 A;  4DLO A;  3P5P A;  1W7C A;  3EJT A;  3ANI A;  1GLM A;  1RKY A;  3M7E A;  3LVT A;  1TN6 B;  3I3D A;  4K35 A;  1G87 A;  2BRV X;  2GOX A;  3HXC B;  1MMY A;  1TXK A;  1SA5 B;  3VD9 A;  1NC5 A;  3D3I A;  4YDE B;  5C05 A;  5IKA A;  2FUZ A;  2WYH A;  2RDY A;  1X1H A;  3BVW A;  3PYA A;  3BVT A;  1W2Z A;  3N0F A;  3OBA A;  4QT9 A;  3MV0 1;  3S4D A;  3BVV A;  1AYX A;  2D8L A;  5GZK A;  4AQ0 A;  2WVX B;  3M76 A;  3SX1 A;  1NL4 B;  1SA4 B;  2F0Y B;  2FV0 A;  1L1Y A;  2WO0 A;  2E24 A;  2G0D A;  3WKH A;  4M76 A;  4DOD A;  4BZH A;  3Q73 B;  1OJO A;  3M00 A;  2OOV C;  1RWA A;  3DYM A;  3A24 A;  1HMU A;  1TN7 B;  2WVY A;  4FNU A;  1R76 A;  1N24 A;  2WIN B;  4FNV A;  3U7V A;  3E32 B;  3QSP A;  1PX4 A;  3BLC A;  1D6Z A;  4BTY A;  3RSY A;  3SDT A;  5FO8 B;  1NI1 B;  3WC3 A;  2WMH A;  3BVU A;  2DRO A;  1TQV A;  3DX0 A;  4D4A A;  4F10 A;  3DSS B;  3S4A A;  4FNT A;  3S4B A;  1A2V A;  4D6G A;  1NS7 A;  3OED A;  2WW2 A;  4GAX A;  4UFC A;  4MMH A;  2JKA A;  2DRR A;  4FNR A;  3M73 A;  1X9D A;  5E2J A;  2E2V A;  4TTG A;  1FMI A;  1QQF A;  1FPP B;  1N4S B;  4ZH5 A;  3K25 A;  3G4D A;  3ANK A;  2WDA A;  3T0A A;  1TF4 A;  2WY7 A;  3KBT C;  3Q78 B;  1S63 B;  2BB5 A;  3WIQ A;  3BGA A;  1O5M B;  1EGU A;  4LNB B;  4FXG B;  3VDC A;  2J5C A;  3P2C A;  1YQ2 A;  2ZQ0 A;  2ALW A;  1NSX A;  4KKJ A;  3E6U A;  4D4C A;  4DOE A;  3T2O A;  2OW7 A;  5DHK A;  5JPN B;  5JMD A;  4Z4J A;  1TNO B;  1FBO A;  3HXE B;  1SII A;  5ILH A;  1W4N A;  3M72 A;  3KSL B;  1F4H A;  3WVF A;  3W7T A;  2XN1 A;  4YCR A;  3NFV A;  3MUY 1;  1FP3 A;  3WKG A;  4KFE A;  2SQC A;  2FUQ A;  3BUB A;  1KRF A;  1N95 B;  1JZ7 A;  1RQ5 A;  1JYX A;  1TU5 A;  5MEH A;  2V8I A;  3Q7F B;  1MMZ A;  1V7W A;  1IU7 A;  1N4P B;  3VD4 A;  4GTV B;  3EU8 A;  3HII A;  1SQC A;  2YFN A;  4CE7 A;  3GZK A;  3QWT A;  1HX9 A;  2XHN A;  3J7H A;  4K3A A;  1N4Q B;  5ILI A;  1I8Q A;  4BTW A;  2V3N A;  3WA3 A;  3D50 A;  2RI8 A;  3T0U A;  2AFA A;  3GLY A;  4GL3 A;  3DX1 A;  1QWN A;  3Q79 B;  2E22 A;  3WKF A;  2XWB B;  2XFG A;  1LD8 B;  2KXR A;  2WMI A;  1H14 A;  4OK4 A;  1H39 A;  4XUV A;  3E34 B;  1IQY A;  2WMJ A;  2CWU A;  3WIW A;  3HXB B;  3DSU B;  1D6U A;  2CQS A;  2QNO A;  3E80 A;  2BRW A;  5IK6 A;  3N0G A;  1CB8 A;  3H3K A;  1LTX B;  3M02 A;  4KFF A;  1NS8 A;  3HXD B;  3MUZ 1;  3SDR A;  1SNZ A;  1WU5 A;  4L0G A;  4D4D A;  3MI6 A;  4GTS B;  3W7X A;  2ZL8 A;  2WY8 A;  3RX7 A;  3ANJ A;  2CQT A;  3REN A;  3D5S A;  4RNQ A;  2ONH A;  3W5M A;  1GHQ A;  2G02 A;  1LXK A;  3NBJ A;  4CJ1 A;  2XQW A;  2WMF A;  1IVU A;  2IEJ B;  3DSV B;  3SXX A;  5KBP A;  3CZN A;  3QT9 A;  1TQT A;  5E1Q A;  3QDE A;  3QR8 A;  1KS8 A;  3BS6 A;  2A73 B;  2WOH A;  2WGQ A;  2WW1 A;  1V5D A;  4GTP B;  2CFW A;  3D52 A;  3BUD A;  1KZO B;  1W5Z A;  1TNZ B;  5IK9 A;  2CFL A;  3ALA A;  2RI9 A;  3N9H A;  4NEI A;  1JS4 A;  1TN8 B;  1HZF A;  1W6K A;  2FV1 A;  5FO9 B;  1X1J A;  2VN7 A;  1KSI A;  3VXD A;  2F6D A;  3ECQ A;  1JZ5 A;  3PZ2 B;  1UMP A;  4AYR A;  2CWV A;  1QAF A;  3MV1 1;  3DDG A;  3M71 A;  1NS2 A;  1N20 A;  2FBA A;  1W3Y A;  1UI7 A;  1JZ6 A;  4KKI A;  4D8O A;  1FCE A;  2PN5 A;  4V1R A;  3H2W A;  2H6I B;  1MMU A;  3NNB A;  3X40 A;  2KXS A;  3TF4 A;  2F7Q A;  2Y74 A;  3RRS A;  1HXA A;  3M7B A;  4WVB A;  3RJ3 A;  3KLS A;  4DUV A;  2WMG A;  2BED B;  4EV5 A;  5JMF A;  2BB6 A; 
#chains in the Genus database with same CATH homology
 1OJN A;  4OZV A;  4D6J A;  1YGA A;  3IMH A;  1RWC A;  1HM2 A;  1C82 A;  3BGA A;  1EGU A;  1DP0 A;  3OB8 A;  4E1Y A;  3TY1 A;  3VDC A;  1N7P A;  2XSG A;  3DYP A;  1YQ2 A;  1JYN A;  4D6I A;  1MMX A;  2ZQ0 A;  2CIQ A;  1HMW A;  1NSX A;  4D6C A;  1SO0 A;  3T2O A;  2WZS A;  1LOH A;  3NJV A;  2HTA A;  1JZ4 A;  1JYV A;  3VD5 A;  5JMD A;  3AFL A;  3T0A A;  1X1I A;  1N7O A;  1F4H A;  3WVF A;  3NFV A;  2WCO A;  1NSM A;  3MUY 1;  1HV6 A;  1JZ8 A;  1L7K A;  4DUX A;  3T2Q A;  1LXM A;  1K1Y A;  1N7Q A;  2FUQ A;  1HM3 A;  1RWG A;  2ZXQ A;  3T0B A;  4BZE A;  1JZ7 A;  1QAZ A;  1JYX A;  3WFA A;  2WMK A;  1MMZ A;  3VD4 A;  3VSN A;  2WVZ A;  3SEP A;  1OJM A;  1NKG A;  2FUT A;  2XHN A;  2CIR A;  3J7H A;  1I8Q A;  4OK2 A;  4D6F A;  4J5T A;  1JZ3 A;  2CIS A;  1N7N A;  1NS0 A;  1J0M A;  3OS7 A;  4OJZ A;  1LF6 A;  3I3E A;  3I3B A;  2E22 A;  1NS4 A;  2Q1F A;  2WMI A;  4OK4 A;  1NSU A;  1UG9 A;  2WW0 A;  4F13 A;  3VD3 A;  2WW3 A;  3DEC A;  1L7J A;  3NRE A;  2WMJ A;  3Q1N A;  3MWX A;  1ULV A;  1F4A A;  3E80 A;  1MN0 A;  1PX3 A;  3T2P A;  2BRW A;  1J0N A;  3I3D A;  1JZ2 A;  1JOV A;  2BRV X;  1CB8 A;  1K1W A;  1MMY A;  1TXK A;  3VD9 A;  1NS8 A;  4D72 A;  4BZF A;  3MUZ 1;  1N7R A;  1SNZ A;  1LUR A;  2D73 A;  3T08 A;  4OZW A;  1X1H A;  4D6E A;  2JKE A;  1NSR A;  1RWF A;  1LXK A;  3IAQ A;  3VDA A;  3T0D A;  3OBA A;  2WVX A;  1LF9 A;  3MV0 1;  2WMF A;  4DUW A;  4AQ0 A;  2WVX B;  3CZJ A;  5E1Q A;  5A1A A;  2BRP A;  3BS6 A;  3E1F 1;  2E24 A;  1NSV A;  4D6D A;  2WW1 A;  1RWH A;  3VSM A;  4BZH A;  2JKP A;  1OJO A;  1JYW A;  1RWA A;  1HN0 A;  4NEI A;  2X03 A;  3DYM A;  3A24 A;  1HMU A;  2WVY A;  1HN1 A;  1F1S A;  1X1J A;  2HTB A;  4FNV A;  4BZG A;  1PX4 A;  4MMI A;  3BLC A;  2WMH A;  3ECQ A;  3VD7 A;  1JZ5 A;  3VDB A;  3T09 A;  2WMI B;  4D71 A;  3MV1 1;  4F10 A;  1OJP A;  4RNL A;  3DYO A;  1NS2 A;  4D6G A;  3DCD A;  1NS7 A;  2WW2 A;  1JZ6 A;  1W3Y A;  3NJX A;  1NSZ A;  4MMH A;  2JKA A;  1K1X A;  3IAP A;  1MMU A;  3NNB A;  1RW9 A;  1NSS A;  3A0O A;  4TTG A;  3K25 A;  4DUV A;  1F9G A;  4D6H A;  1Z45 A;  2WDA A;  2WMG A;  3E7J A;  5JMF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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