1HPJA

Solution nmr structure of the human plasminogen kringle 1 domain complexed with 6-aminohexanoic acid at ph 5.3, 310k, derived from randomly generated structures using simulated annealing, 12 structures
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
79
structure length
79
Chain Sequence
CKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the epsilon-aminohexanoic acid complex of human plasminogen kringle 1.
pubmed doi rcsb
molecule keywords PLASMINOGEN
molecule tags Serine protease
total genus 10
structure length 79
sequence length 79
ec nomenclature ec 3.4.21.7: Plasmin.
pdb deposition date 1996-08-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 1hpjA00
1KDUA 1HPJA 3U73A 3HN4A 1GP9A 3MKPA 5CP9A 5HPGA 1PK2A 4BV7A 4D3CA 2PF2A 3SP8A 2I9AA 2QJ2A 5CS5A 4O03A 2PK4A 1BHTA 1JFNA 4DURA 4BVWA 1HPKA 1B2IA 1NL2A 2I9BA 1A0HA 1NK1A 4BV5A 1CEAA 2PF1A 1KRNA 4NZQA 1PKRA 2KJ4A 3E6PL 3BT1A 1CEBA 2HPQP 5CS3A 2QJ4A 4BVDA 1TPKA 2FEBA 2SPTA 4BVCA 5CT2A 4A5TS 5CT1A 4HZHA 4BVVA 4KIVA 5COEA 5CS1A 2L0SA 2DOIA 2FD6A 2DOHX 1PMKA 3LAQA 3K65A 3KIVA 1PMLA 2HPPP 1GMNA 1I5KA 1KIVA 5CS9A 2K4RA 1NL1A 2KNFA 1URKA 5CT3A 1GMOA 1KI0A 1PK4A 3NXPA 1I71A 3BT2A 4CIKA 4IUAA 2K51A 5CSQA
chains in the Genus database with same CATH superfamily
1KDUA 1HPJA 3U73A 3HN4A 1GP9A 3MKPA 5CP9A 5HPGA 1PK2A 4BV7A 4D3CA 2PF2A 3SP8A 2I9AA 2QJ2A 5CS5A 4O03A 2PK4A 1BHTA 1JFNA 4DURA 4BVWA 1HPKA 1B2IA 1NL2A 2I9BA 1A0HA 1NK1A 4BV5A 1CEAA 2PF1A 1KRNA 4NZQA 1PKRA 2KJ4A 3E6PL 3BT1A 1CEBA 2HPQP 5CS3A 2QJ4A 4BVDA 1TPKA 2FEBA 2SPTA 4BVCA 5CT2A 4A5TS 5CT1A 4HZHA 4BVVA 4KIVA 5COEA 5CS1A 2L0SA 2DOIA 2FD6A 2DOHX 1PMKA 3LAQA 3K65A 3KIVA 1PMLA 2HPPP 1GMNA 1I5KA 1KIVA 5CS9A 2K4RA 1NL1A 2KNFA 1URKA 5CT3A 1GMOA 1KI0A 1PK4A 3NXPA 1I71A 3BT2A 4CIKA 4IUAA 2K51A 5CSQA
chains in the Genus database with same CATH topology
1KDUA 1HPJA 3U73A 3HN4A 1GP9A 3MKPA 5CP9A 5HPGA 1PK2A 4BV7A 4D3CA 2PF2A 3SP8A 2I9AA 2QJ2A 5CS5A 4O03A 2PK4A 1BHTA 1JFNA 4DURA 4BVWA 1HPKA 1B2IA 1NL2A 2I9BA 1A0HA 1NK1A 4BV5A 1CEAA 2PF1A 1KRNA 4NZQA 1PKRA 2KJ4A 3E6PL 3BT1A 1CEBA 2HPQP 5CS3A 2QJ4A 4BVDA 1TPKA 2FEBA 2SPTA 4BVCA 5CT2A 4A5TS 5CT1A 4HZHA 4BVVA 4KIVA 5COEA 5CS1A 2L0SA 2DOIA 2FD6A 2DOHX 1PMKA 3LAQA 3K65A 3KIVA 1PMLA 2HPPP 1GMNA 1I5KA 1KIVA 5CS9A 2K4RA 1NL1A 2KNFA 1URKA 5CT3A 1GMOA 1KI0A 1PK4A 3NXPA 1I71A 3BT2A 4CIKA 4IUAA 2K51A 5CSQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KDU A;  1HPJ A;  3U73 A;  3HN4 A;  1GP9 A;  3MKP A;  5CP9 A;  5HPG A;  1PK2 A;  4BV7 A;  4D3C A;  2PF2 A;  3SP8 A;  2I9A A;  2QJ2 A;  5CS5 A;  4O03 A;  2PK4 A;  1BHT A;  1JFN A;  4DUR A;  4BVW A;  1HPK A;  1B2I A;  1NL2 A;  2I9B A;  1A0H A;  1NK1 A;  4BV5 A;  1CEA A;  2PF1 A;  1KRN A;  4NZQ A;  1PKR A;  2KJ4 A;  3E6P L;  3BT1 A;  1CEB A;  2HPQ P;  5CS3 A;  2QJ4 A;  4BVD A;  1TPK A;  2FEB A;  2SPT A;  4BVC A;  5CT2 A;  4A5T S;  5CT1 A;  4HZH A;  4BVV A;  4KIV A;  5COE A;  5CS1 A;  2L0S A;  2DOI A;  2FD6 A;  2DOH X;  1PMK A;  3LAQ A;  3K65 A;  3KIV A;  1PML A;  2HPP P;  1GMN A;  1I5K A;  1KIV A;  5CS9 A;  2K4R A;  1NL1 A;  2KNF A;  1URK A;  5CT3 A;  1GMO A;  1KI0 A;  1PK4 A;  3NXP A;  1I71 A;  3BT2 A;  4CIK A;  4IUA A;  2K51 A;  5CSQ A; 
#chains in the Genus database with same CATH topology
 1KDU A;  1HPJ A;  3U73 A;  3HN4 A;  1GP9 A;  3MKP A;  5CP9 A;  5HPG A;  1PK2 A;  4BV7 A;  4D3C A;  2PF2 A;  3SP8 A;  2I9A A;  2QJ2 A;  5CS5 A;  4O03 A;  2PK4 A;  1BHT A;  1JFN A;  4DUR A;  4BVW A;  1HPK A;  1B2I A;  1NL2 A;  2I9B A;  1A0H A;  1NK1 A;  4BV5 A;  1CEA A;  2PF1 A;  1KRN A;  4NZQ A;  1PKR A;  2KJ4 A;  3E6P L;  3BT1 A;  1CEB A;  2HPQ P;  5CS3 A;  2QJ4 A;  4BVD A;  1TPK A;  2FEB A;  2SPT A;  4BVC A;  5CT2 A;  4A5T S;  5CT1 A;  4HZH A;  4BVV A;  4KIV A;  5COE A;  5CS1 A;  2L0S A;  2DOI A;  2FD6 A;  2DOH X;  1PMK A;  3LAQ A;  3K65 A;  3KIV A;  1PML A;  2HPP P;  1GMN A;  1I5K A;  1KIV A;  5CS9 A;  2K4R A;  1NL1 A;  2KNF A;  1URK A;  5CT3 A;  1GMO A;  1KI0 A;  1PK4 A;  3NXP A;  1I71 A;  3BT2 A;  4CIK A;  4IUA A;  2K51 A;  5CSQ A; 
#chains in the Genus database with same CATH homology
 1KDU A;  1HPJ A;  3U73 A;  3HN4 A;  1GP9 A;  3MKP A;  5CP9 A;  5HPG A;  1PK2 A;  4BV7 A;  4D3C A;  2PF2 A;  3SP8 A;  2I9A A;  2QJ2 A;  5CS5 A;  4O03 A;  2PK4 A;  1BHT A;  1JFN A;  4DUR A;  4BVW A;  1HPK A;  1B2I A;  1NL2 A;  2I9B A;  1A0H A;  1NK1 A;  4BV5 A;  1CEA A;  2PF1 A;  1KRN A;  4NZQ A;  1PKR A;  2KJ4 A;  3E6P L;  3BT1 A;  1CEB A;  2HPQ P;  5CS3 A;  2QJ4 A;  4BVD A;  1TPK A;  2FEB A;  2SPT A;  4BVC A;  5CT2 A;  4A5T S;  5CT1 A;  4HZH A;  4BVV A;  4KIV A;  5COE A;  5CS1 A;  2L0S A;  2DOI A;  2FD6 A;  2DOH X;  1PMK A;  3LAQ A;  3K65 A;  3KIV A;  1PML A;  2HPP P;  1GMN A;  1I5K A;  1KIV A;  5CS9 A;  2K4R A;  1NL1 A;  2KNF A;  1URK A;  5CT3 A;  1GMO A;  1KI0 A;  1PK4 A;  3NXP A;  1I71 A;  3BT2 A;  4CIK A;  4IUA A;  2K51 A;  5CSQ A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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