1I4SA

Crystal structure of rnase iii endonuclease domain from aquifex aeolicus at 2.15 angstrom resolution
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
147
structure length
147
Chain Sequence
MKMLEQLEKKLGYTFKDKSLLEKALTHVSYSKKEHYETLEFLGDALVNFFIVDLLVQYSPNKREGFLSPLKAYLISEEFFNLLAQKLELHKFIRIKRGKINETIIGDVFEALWAAVYIDSGRDANFTRELFYKLFKEDILSAIKEGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords RIBONUCLEASE III
publication title Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage.
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
total genus 45
structure length 147
sequence length 147
chains with identical sequence B
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2001-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00636 Ribonuclease_3 Ribonuclease III domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1520.10 Mainly Alpha Orthogonal Bundle Ribonuclease iii, N-terminal Endonuclease Domain; Chain A Ribonuclease III domain 1i4sA00
1YZ9A 3O2RA 4OOGC 1RC7A 1RC5A 1O0WA 3RV0A 1U61A 2FFLA 4OUNA 2GSLA 2NUGA 3N3WA 3C4BA 2A11A 3O2RB 4M30A 3RV1A 2NUFA 3C4TA 2EB1A 2QVWA 2EZ6A 1YYKA 1YYOA 2NUEA 1YYWA 4M2ZA 1JFZA 1I4SA
chains in the Genus database with same CATH superfamily
1YZ9A 3O2RA 4OOGC 1RC7A 1RC5A 1O0WA 3RV0A 1U61A 2FFLA 4OUNA 2GSLA 2NUGA 3N3WA 3C4BA 2A11A 3O2RB 4M30A 3RV1A 2NUFA 3C4TA 2EB1A 2QVWA 2EZ6A 1YYKA 1ZTDA 1YYOA 2NUEA 1YYWA 4M2ZA 1JFZA 1I4SA
chains in the Genus database with same CATH topology
1YZ9A 3O2RA 4OOGC 1RC7A 1RC5A 1O0WA 3RV0A 1U61A 2FFLA 4OUNA 2GSLA 2NUGA 3N3WA 3C4BA 2A11A 3O2RB 4M30A 3RV1A 2NUFA 3C4TA 2EB1A 2QVWA 2EZ6A 1YYKA 1YYOA 2NUEA 1YYWA 4M2ZA 1JFZA 1I4SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YZ9 A;  3O2R A;  4OOG C;  1RC7 A;  1RC5 A;  1O0W A;  3RV0 A;  1U61 A;  2FFL A;  4OUN A;  2GSL A;  2NUG A;  3N3W A;  3C4B A;  2A11 A;  3O2R B;  4M30 A;  3RV1 A;  2NUF A;  3C4T A;  2EB1 A;  2QVW A;  2EZ6 A;  1YYK A;  1YYO A;  2NUE A;  1YYW A;  4M2Z A;  1JFZ A;  1I4S A; 
#chains in the Genus database with same CATH topology
 1YZ9 A;  3O2R A;  4OOG C;  1RC7 A;  1RC5 A;  1O0W A;  3RV0 A;  1U61 A;  2FFL A;  4OUN A;  2GSL A;  2NUG A;  3N3W A;  3C4B A;  2A11 A;  3O2R B;  4M30 A;  3RV1 A;  2NUF A;  3C4T A;  2EB1 A;  2QVW A;  2EZ6 A;  1YYK A;  1ZTD A;  1YYO A;  2NUE A;  1YYW A;  4M2Z A;  1JFZ A;  1I4S A; 
#chains in the Genus database with same CATH homology
 1YZ9 A;  3O2R A;  4OOG C;  1RC7 A;  1RC5 A;  1O0W A;  3RV0 A;  1U61 A;  2FFL A;  4OUN A;  2GSL A;  2NUG A;  3N3W A;  3C4B A;  2A11 A;  3O2R B;  4M30 A;  3RV1 A;  2NUF A;  3C4T A;  2EB1 A;  2QVW A;  2EZ6 A;  1YYK A;  1YYO A;  2NUE A;  1YYW A;  4M2Z A;  1JFZ A;  1I4S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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