1I50L

Rna polymerase ii crystal form ii at 2.8 a resolution
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2001-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1i50L00
3H0GL 2JA8L 3M3YL 1K83L 2WAQP 3HOYL 3RZOL 4A3BL 5FJ8L 1TWGL 3HKZP 5M3FL 3HOWL 4C3JL 4A3JL 3S1ML 2VUML 2PMZP 3S16L 3GTJL 3HOVL 3PO3L 1I3QL 3HOUL 3H3VM 4A3CL 3HOZL 3I4NL 3S2HL 1TWFL 3S14L 2E2JL 3GTML 5C44L 3S17L 3K7AL 3FKIL 5IP7L 3GTLL 3I4ML 2NVTL 2B63L 2NVXL 3S2DL 2JA6L 2YU9L 5IP9L 3S1QL 4X6AL 4A3LL 5M5YL 1TWHL 4BXXL 4BBSL 1Y1VL 4AYBP 5C4XL 5IYCL 4BY7L 2NVQL 2E2IL 1SFOL 2JA7L 4A3EL 4Y7NL 4A3FL 2WB1P 1Y1WL 5M3ML 1R9TL 1I6HL 2R92L 4BBRL 3PO2L 4C3HL 2NVYL 4Y52L 4A3KL 2E2HL 4BY1L 4A93L 2R93L 4A3DL 2Y0SP 3GTKL 5IYDL 3S1RL 1I50L 1WCML 5M5WL 5IYBL 1TWAL 3S15L 3GTOL 5C4JL 4A3IL 3GTQL 3S1NL 3HOXL 5C3EL 3GTPL 2JA5L 3CQZL 5M5XL 4A3ML 1TWCL 4QIWP 3M4OL 4C3IL 2R7ZL 3GTGL 4A3GL 3RZDL 5FLML 4C2M1
chains in the Genus database with same CATH superfamily
4ZN1B 2H12A 1F4LA 5AN9H 3H0GL 1BE7A 3RZOL 2EY4E 7RXNA 3HKZP 1CAAA 3H9CA 4C3JL 5DM61 1NXGA 3NFPI 2GMGA 4GS7D 1I3QL 3MPSA 4POGA 3HOUL 1S30A 3H3VM 4A3CL 1B2OA 2NYDA 1TWFL 5GADc 2LCQA 2E2JL 2ZIXA 3S17L 3FKIL 2JI1A 1H7VA 2NVTL 1PFVA 3PIP1 2NVXL 3S2DL 2KN9A 1JYBA 5DM71 3S1QL 4BXXL 3PWFA 3P2AA 2E2IL 1SFOL 4A3EL 4AI0A 4Y7NL 4A3FL 1R9TL 4BBRL 4LHNA 4AHWA 4LHLA 2NVYL 1ODHA 2AUSB 3HAXC 2APOB 4AI3A 4JAFA 2R93L 4A3DL 3LWOB 3GTKL 3PKIA 1YUXA 3ZG6A 5MF6A 2XJUA 5GAEc 3PZAA 5C4JL 2AYJA 1QCVA 2CKCA 3VPBE 4AR6A 1R0HA 5GAHc 2J9UB 3HOXL 1IRNA 2V0FA 1FHHA 3WWLA 5M5XL 5JVH1 4AI1A 4QIWP 1C09A 4C3IL 1LKMA 1SMUA 1BQ8A 2PYAA 3RZDL 1T9OA 2C6BA 2M4YA 2JA8L 1ZRPA 3HOYL 5FJ8L 1TWGL 3LWRB 4WFN1 4V196 2L0ZA 3S1ML 1Z92B 5AI3A 2VUML 2MS3A 4RXNA 3RYGA 5AI2A 3I4NL 2CR8A 2M6PA 4YWLA 3S2HL 2VL6A 3S14L 1R0JA 5C44L 1IROA 3I4ML 3MSUA 4POFA 2YU9L 5IP9L 3A44A 4A3LL 4BBSL 3RZ6A 2B5ID 3LNLA 2PVEA 5IYCL 4BY7L 3QQCE 1Y1WL 1LKPA 3JR7A 1DX8A 1SMWA 3B08B 4JAGA 3PO2L 3K35A 4AR3A 4Y52L 2E2HL 4BY1L 3H9BA 1RB9A 2A69D 5IYDL 2XJQA 3S1RL 1I50L 3J7Z1 1WCML 1TWAL 3S15L 1RDGA 3GTOL 1RYQA 1DVBA 4UY81 5C3EL 4XXBB 1IU5A 2JA5L 3CQZL 1R0GA 1OWCA 2Z3RB 4XGHA 1NNQA 3GTGL 3MQKB 5FLML 4C2M1 1VZGA 1YUZA 1LKOA 1K83L 3KYWA 5MFPA 4A3BL 2XJVA 1PZXA 3HOWL 5M3FL 4K9FA 2M6OA 1IU6A 2HVYC 2QL0A 3PL5A 5EIOC 3KYYA 4AR4A 3HJYB 4AHXA 3HOVL 3HJWB 5MFZA 1QQTA 3K7AL 3GTLL 2BE5D 1OWBA 2K2DA 2ERSA 2PPTA 2JA6L 1T9PA 4AI2A 4X6AL 1TWHL 4AYBP 4G6BA 2NVQL 1VCXA 5MGNA 1I6HL 1S2ZA 5M3ML 1YV1A 1B13A 2M4VA 1RDVA 4C3HL 1RYTA 3LWVB 1PFWA 6RXNA 2JI2A 4JADA 3SS2A 1R0IA 5M5WL 5IYBL 1VZIA 1FHMA 3J7Y1 2O5JD 4TPUA 2Z3QB 4A3IL 3WWNB 3S1NL 1R0FA 3GTPL 2V3BB 3KYUA 1B2JA 3RZTA 2PSMC 2XJPA 4ZN3B 4A3ML 1E8JA 1TWCL 2JI3A 4B8CD 4E6YA 4ME3A 3PIO1 3M4OL 1S24A 3B0AB 2DSXA 3KYXA 2A6ED 5IY0A 2V0EA 1CADA 2HR5A 3H99A 2RDVA 2A6HD 3M3YL 1RWDA 2WAQP 2XJRA 5RXNA 1LTLA 1BQ9A 3FDJA 4A3JL 5GAGc 2KKDA 2PMZP 2ERJA 3S16L 3GTJL 3PO3L 3KYVA 1NXEA 8RXNA 2CKAA 3HOZL 1PFYA 3GTML 1VZHA 2RFKB 5IP7L 2PVXA 4AHZA 2A68D 4YWMA 2B63L 1B71A 1YK4A 1P7PA 5M5YL 4TVMA 1Y1VL 1SMMA 2AQCA 5C4XL 3LPEB 2XJTA 1T9QA 5MLC3 2JA7L 1IW7D 5JVG1 3LWPB 2C6AA 3LWQB 2WB1P 2R92L 1BRFA 4A3KL 5H1Sc 4A93L 4AHYA 2Y0SP 1YK5A 2XJSA 1PFUA 3P8BA 4AR5A 5K2ME 3PKJA 1BFYA 3GTQL 1QYBA 5EINC 3H97A 3IU3I 3QVDA 4JAEA 4U671 2R7ZL 4A3GL 1WJVA
chains in the Genus database with same CATH topology
3H0GL 2JA8L 3M3YL 1K83L 2WAQP 3HOYL 3RZOL 4A3BL 5FJ8L 1TWGL 3HKZP 5M3FL 3HOWL 4C3JL 4A3JL 3S1ML 2VUML 2PMZP 3S16L 3GTJL 3HOVL 3PO3L 1I3QL 3HOUL 3H3VM 4A3CL 3HOZL 3I4NL 3S2HL 1TWFL 3S14L 2E2JL 3GTML 5C44L 3S17L 3K7AL 3FKIL 5IP7L 3GTLL 3I4ML 2NVTL 2B63L 2NVXL 3S2DL 2JA6L 2YU9L 5IP9L 3S1QL 4X6AL 4A3LL 5M5YL 1TWHL 4BXXL 4BBSL 1Y1VL 4AYBP 5C4XL 5IYCL 4BY7L 2NVQL 2E2IL 1SFOL 2JA7L 4A3EL 4Y7NL 4A3FL 2WB1P 1Y1WL 5M3ML 1R9TL 1I6HL 2R92L 4BBRL 3PO2L 4C3HL 2NVYL 4Y52L 4A3KL 2E2HL 4BY1L 4A93L 2R93L 4A3DL 2Y0SP 3GTKL 5IYDL 3S1RL 1I50L 1WCML 5M5WL 5IYBL 1TWAL 3S15L 3GTOL 5C4JL 4A3IL 3GTQL 3S1NL 3HOXL 5C3EL 3GTPL 2JA5L 3CQZL 5M5XL 4A3ML 1TWCL 4QIWP 3M4OL 4C3IL 2R7ZL 3GTGL 4A3GL 3RZDL 5FLML 4C2M1
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H0G L;  2JA8 L;  3M3Y L;  1K83 L;  2WAQ P;  3HOY L;  3RZO L;  4A3B L;  5FJ8 L;  1TWG L;  3HKZ P;  5M3F L;  3HOW L;  4C3J L;  4A3J L;  3S1M L;  2VUM L;  2PMZ P;  3S16 L;  3GTJ L;  3HOV L;  3PO3 L;  1I3Q L;  3HOU L;  3H3V M;  4A3C L;  3HOZ L;  3I4N L;  3S2H L;  1TWF L;  3S14 L;  2E2J L;  3GTM L;  5C44 L;  3S17 L;  3K7A L;  3FKI L;  5IP7 L;  3GTL L;  3I4M L;  2NVT L;  2B63 L;  2NVX L;  3S2D L;  2JA6 L;  2YU9 L;  5IP9 L;  3S1Q L;  4X6A L;  4A3L L;  5M5Y L;  1TWH L;  4BXX L;  4BBS L;  1Y1V L;  4AYB P;  5C4X L;  5IYC L;  4BY7 L;  2NVQ L;  2E2I L;  1SFO L;  2JA7 L;  4A3E L;  4Y7N L;  4A3F L;  2WB1 P;  1Y1W L;  5M3M L;  1R9T L;  1I6H L;  2R92 L;  4BBR L;  3PO2 L;  4C3H L;  2NVY L;  4Y52 L;  4A3K L;  2E2H L;  4BY1 L;  4A93 L;  2R93 L;  4A3D L;  2Y0S P;  3GTK L;  5IYD L;  3S1R L;  1I50 L;  1WCM L;  5M5W L;  5IYB L;  1TWA L;  3S15 L;  3GTO L;  5C4J L;  4A3I L;  3GTQ L;  3S1N L;  3HOX L;  5C3E L;  3GTP L;  2JA5 L;  3CQZ L;  5M5X L;  4A3M L;  1TWC L;  4QIW P;  3M4O L;  4C3I L;  2R7Z L;  3GTG L;  4A3G L;  3RZD L;  5FLM L;  4C2M 1; 
#chains in the Genus database with same CATH topology
 4ZN1 B;  2H12 A;  1F4L A;  5AN9 H;  3H0G L;  1BE7 A;  3RZO L;  2EY4 E;  7RXN A;  3HKZ P;  1CAA A;  3H9C A;  4C3J L;  5DM6 1;  1NXG A;  3NFP I;  2GMG A;  4GS7 D;  1I3Q L;  3MPS A;  4POG A;  3HOU L;  1S30 A;  3H3V M;  4A3C L;  1B2O A;  2NYD A;  1TWF L;  5GAD c;  2LCQ A;  2E2J L;  2ZIX A;  3S17 L;  3FKI L;  2JI1 A;  1H7V A;  2NVT L;  1PFV A;  3PIP 1;  2NVX L;  3S2D L;  2KN9 A;  1JYB A;  5DM7 1;  3S1Q L;  4BXX L;  3PWF A;  3P2A A;  2E2I L;  1SFO L;  4A3E L;  4AI0 A;  4Y7N L;  4A3F L;  1R9T L;  4BBR L;  4LHN A;  4AHW A;  4LHL A;  2NVY L;  1ODH A;  2AUS B;  3HAX C;  2APO B;  4AI3 A;  4JAF A;  2R93 L;  4A3D L;  3LWO B;  3GTK L;  3PKI A;  1YUX A;  3ZG6 A;  5MF6 A;  2XJU A;  5GAE c;  3PZA A;  5C4J L;  2AYJ A;  1QCV A;  2CKC A;  3VPB E;  4AR6 A;  1R0H A;  5GAH c;  2J9U B;  3HOX L;  1IRN A;  2V0F A;  1FHH A;  3WWL A;  5M5X L;  5JVH 1;  4AI1 A;  4QIW P;  1C09 A;  4C3I L;  1LKM A;  1SMU A;  1BQ8 A;  2PYA A;  3RZD L;  1T9O A;  2C6B A;  2M4Y A;  2JA8 L;  1ZRP A;  3HOY L;  5FJ8 L;  1TWG L;  3LWR B;  4WFN 1;  4V19 6;  2L0Z A;  3S1M L;  1Z92 B;  5AI3 A;  2VUM L;  2MS3 A;  4RXN A;  3RYG A;  5AI2 A;  3I4N L;  2CR8 A;  2M6P A;  4YWL A;  3S2H L;  2VL6 A;  3S14 L;  1R0J A;  5C44 L;  1IRO A;  3I4M L;  3MSU A;  4POF A;  2YU9 L;  5IP9 L;  3A44 A;  4A3L L;  4BBS L;  3RZ6 A;  2B5I D;  3LNL A;  2PVE A;  5IYC L;  4BY7 L;  3QQC E;  1Y1W L;  1LKP A;  3JR7 A;  1DX8 A;  1SMW A;  3B08 B;  4JAG A;  3PO2 L;  3K35 A;  4AR3 A;  4Y52 L;  2E2H L;  4BY1 L;  3H9B A;  1RB9 A;  2A69 D;  5IYD L;  2XJQ A;  3S1R L;  1I50 L;  3J7Z 1;  1WCM L;  1TWA L;  3S15 L;  1RDG A;  3GTO L;  1RYQ A;  1DVB A;  4UY8 1;  5C3E L;  4XXB B;  1IU5 A;  2JA5 L;  3CQZ L;  1R0G A;  1OWC A;  2Z3R B;  4XGH A;  1NNQ A;  3GTG L;  3MQK B;  5FLM L;  4C2M 1;  1VZG A;  1YUZ A;  1LKO A;  1K83 L;  3KYW A;  5MFP A;  4A3B L;  2XJV A;  1PZX A;  3HOW L;  5M3F L;  4K9F A;  2M6O A;  1IU6 A;  2HVY C;  2QL0 A;  3PL5 A;  5EIO C;  3KYY A;  4AR4 A;  3HJY B;  4AHX A;  3HOV L;  3HJW B;  5MFZ A;  1QQT A;  3K7A L;  3GTL L;  2BE5 D;  1OWB A;  2K2D A;  2ERS A;  2PPT A;  2JA6 L;  1T9P A;  4AI2 A;  4X6A L;  1TWH L;  4AYB P;  4G6B A;  2NVQ L;  1VCX A;  5MGN A;  1I6H L;  1S2Z A;  5M3M L;  1YV1 A;  1B13 A;  2M4V A;  1RDV A;  4C3H L;  1RYT A;  3LWV B;  1PFW A;  6RXN A;  2JI2 A;  4JAD A;  3SS2 A;  1R0I A;  5M5W L;  5IYB L;  1VZI A;  1FHM A;  3J7Y 1;  2O5J D;  4TPU A;  2Z3Q B;  4A3I L;  3WWN B;  3S1N L;  1R0F A;  3GTP L;  2V3B B;  3KYU A;  1B2J A;  3RZT A;  2PSM C;  2XJP A;  4ZN3 B;  4A3M L;  1E8J A;  1TWC L;  2JI3 A;  4B8C D;  4E6Y A;  4ME3 A;  3PIO 1;  3M4O L;  1S24 A;  3B0A B;  2DSX A;  3KYX A;  2A6E D;  5IY0 A;  2V0E A;  1CAD A;  2HR5 A;  3H99 A;  2RDV A;  2A6H D;  3M3Y L;  1RWD A;  2WAQ P;  2XJR A;  5RXN A;  1LTL A;  1BQ9 A;  3FDJ A;  4A3J L;  5GAG c;  2KKD A;  2PMZ P;  2ERJ A;  3S16 L;  3GTJ L;  3PO3 L;  3KYV A;  1NXE A;  8RXN A;  2CKA A;  3HOZ L;  1PFY A;  3GTM L;  1VZH A;  2RFK B;  5IP7 L;  2PVX A;  4AHZ A;  2A68 D;  4YWM A;  2B63 L;  1B71 A;  1YK4 A;  1P7P A;  5M5Y L;  4TVM A;  1Y1V L;  1SMM A;  2AQC A;  5C4X L;  3LPE B;  2XJT A;  1T9Q A;  5MLC 3;  2JA7 L;  1IW7 D;  5JVG 1;  3LWP B;  2C6A A;  3LWQ B;  2WB1 P;  2R92 L;  1BRF A;  4A3K L;  5H1S c;  4A93 L;  4AHY A;  2Y0S P;  1YK5 A;  2XJS A;  1PFU A;  3P8B A;  4AR5 A;  5K2M E;  3PKJ A;  1BFY A;  3GTQ L;  1QYB A;  5EIN C;  3H97 A;  3IU3 I;  3QVD A;  4JAE A;  4U67 1;  2R7Z L;  4A3G L;  1WJV A; 
#chains in the Genus database with same CATH homology
 3H0G L;  2JA8 L;  3M3Y L;  1K83 L;  2WAQ P;  3HOY L;  3RZO L;  4A3B L;  5FJ8 L;  1TWG L;  3HKZ P;  5M3F L;  3HOW L;  4C3J L;  4A3J L;  3S1M L;  2VUM L;  2PMZ P;  3S16 L;  3GTJ L;  3HOV L;  3PO3 L;  1I3Q L;  3HOU L;  3H3V M;  4A3C L;  3HOZ L;  3I4N L;  3S2H L;  1TWF L;  3S14 L;  2E2J L;  3GTM L;  5C44 L;  3S17 L;  3K7A L;  3FKI L;  5IP7 L;  3GTL L;  3I4M L;  2NVT L;  2B63 L;  2NVX L;  3S2D L;  2JA6 L;  2YU9 L;  5IP9 L;  3S1Q L;  4X6A L;  4A3L L;  5M5Y L;  1TWH L;  4BXX L;  4BBS L;  1Y1V L;  4AYB P;  5C4X L;  5IYC L;  4BY7 L;  2NVQ L;  2E2I L;  1SFO L;  2JA7 L;  4A3E L;  4Y7N L;  4A3F L;  2WB1 P;  1Y1W L;  5M3M L;  1R9T L;  1I6H L;  2R92 L;  4BBR L;  3PO2 L;  4C3H L;  2NVY L;  4Y52 L;  4A3K L;  2E2H L;  4BY1 L;  4A93 L;  2R93 L;  4A3D L;  2Y0S P;  3GTK L;  5IYD L;  3S1R L;  1I50 L;  1WCM L;  5M5W L;  5IYB L;  1TWA L;  3S15 L;  3GTO L;  5C4J L;  4A3I L;  3GTQ L;  3S1N L;  3HOX L;  5C3E L;  3GTP L;  2JA5 L;  3CQZ L;  5M5X L;  4A3M L;  1TWC L;  4QIW P;  3M4O L;  4C3I L;  2R7Z L;  3GTG L;  4A3G L;  3RZD L;  5FLM L;  4C2M 1; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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