1I8NA

Crystal structure of leech anti-platelet protein
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
89
structure length
89
Chain Sequence
ETITAGNEDCWSKRPGWKLPDNLLTKTEFTSVDECRKMCEESAVEPSCYILQINTETNECYRNNEGDVTWSSLQYDQPNVVQWHLHACS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ANTI-PLATELET PROTEIN
publication title The structure of leech anti-platelet protein, an inhibitor of haemostasis.
pubmed doi rcsb
source organism Haementeria officinalis
molecule tags Toxin
total genus 26
structure length 89
sequence length 89
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2001-03-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 1i8nA00
2LL3A 1W81A 2HGFA 3HN4A 2Q8AA 2Z8VA 4APLA 4A5TS 1Z40A 5CT2A 5CSQA 2J8JA 3HMRA 2QJ2A 4Z0EA 2Z8WA 4R19A 4R1CA 4R1BA 2Y8RA 3HMTA 3HMSA 5CP9A 2YIOA 3MKPA 2Q8BA 4Z0FA 1NK1A 2F83A 2K13X 4DURA 1W8KA 1GMOA 2YILA 4Z09A 1I8NA 1GMNA 3ZLEA 4UV6A 1GP9A 5CS5A 2QJ4A 4Z0DA 4IUAA 3SRIA 3SP8A 3ZWZA 1BHTA 1YXEA 5CS3A 5EOKA 5CS1A 4APMA 5I25A 5EODA 4R1AA 1HKYA 2LL4M 5CS9A 5CT1A 5COEA 2X2ZA 2YIPA 3SRJA 2J8LA 4UAOA 5CT3A
chains in the Genus database with same CATH superfamily
2LL3A 1W81A 2HGFA 3HN4A 2Q8AA 2Z8VA 4APLA 4A5TS 1Z40A 5CT2A 5CSQA 2J8JA 3HMRA 2QJ2A 4YIVA 4Z0EA 2Z8WA 4R19A 4R1CA 4R1BA 2Y8RA 3HMTA 2KL5A 3HMSA 5CP9A 2YIOA 3MKPA 2Q8BA 4Z0FA 1NK1A 2F83A 2K13X 4DURA 1W8KA 1GMOA 2YILA 4Z09A 1I8NA 1GMNA 3ZLEA 4UV6A 1GP9A 5CS5A 2QJ4A 4Z0DA 4IUAA 3SRIA 3SP8A 3ZWZA 1BHTA 1YXEA 5CS3A 5EOKA 5CS1A 4APMA 5I25A 5EODA 4R1AA 1HKYA 2LL4M 5CS9A 5CT1A 5COEA 2X2ZA 2YIPA 3SRJA 2J8LA 4UAOA 4YIZA 5CT3A
chains in the Genus database with same CATH topology
2LL3A 1W81A 2HGFA 3HN4A 2Q8AA 2Z8VA 4APLA 4A5TS 1Z40A 5CT2A 5CSQA 2J8JA 3HMRA 2QJ2A 4YIVA 4Z0EA 2Z8WA 4R19A 4R1CA 4R1BA 2Y8RA 3HMTA 2KL5A 3HMSA 5CP9A 2YIOA 3MKPA 2Q8BA 4Z0FA 1NK1A 2F83A 2K13X 4DURA 1W8KA 1GMOA 2YILA 4Z09A 1I8NA 1GMNA 3ZLEA 4UV6A 1GP9A 5CS5A 2QJ4A 4Z0DA 4IUAA 3SRIA 3SP8A 3ZWZA 1BHTA 1YXEA 5CS3A 5EOKA 5CS1A 4APMA 5I25A 5EODA 4R1AA 1HKYA 2LL4M 5CS9A 5CT1A 5COEA 2X2ZA 2YIPA 3SRJA 2J8LA 4UAOA 4YIZA 5CT3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LL3 A;  1W81 A;  2HGF A;  3HN4 A;  2Q8A A;  2Z8V A;  4APL A;  4A5T S;  1Z40 A;  5CT2 A;  5CSQ A;  2J8J A;  3HMR A;  2QJ2 A;  4Z0E A;  2Z8W A;  4R19 A;  4R1C A;  4R1B A;  2Y8R A;  3HMT A;  3HMS A;  5CP9 A;  2YIO A;  3MKP A;  2Q8B A;  4Z0F A;  1NK1 A;  2F83 A;  2K13 X;  4DUR A;  1W8K A;  1GMO A;  2YIL A;  4Z09 A;  1I8N A;  1GMN A;  3ZLE A;  4UV6 A;  1GP9 A;  5CS5 A;  2QJ4 A;  4Z0D A;  4IUA A;  3SRI A;  3SP8 A;  3ZWZ A;  1BHT A;  1YXE A;  5CS3 A;  5EOK A;  5CS1 A;  4APM A;  5I25 A;  5EOD A;  4R1A A;  1HKY A;  2LL4 M;  5CS9 A;  5CT1 A;  5COE A;  2X2Z A;  2YIP A;  3SRJ A;  2J8L A;  4UAO A;  5CT3 A; 
#chains in the Genus database with same CATH topology
 2LL3 A;  1W81 A;  2HGF A;  3HN4 A;  2Q8A A;  2Z8V A;  4APL A;  4A5T S;  1Z40 A;  5CT2 A;  5CSQ A;  2J8J A;  3HMR A;  2QJ2 A;  4YIV A;  4Z0E A;  2Z8W A;  4R19 A;  4R1C A;  4R1B A;  2Y8R A;  3HMT A;  2KL5 A;  3HMS A;  5CP9 A;  2YIO A;  3MKP A;  2Q8B A;  4Z0F A;  1NK1 A;  2F83 A;  2K13 X;  4DUR A;  1W8K A;  1GMO A;  2YIL A;  4Z09 A;  1I8N A;  1GMN A;  3ZLE A;  4UV6 A;  1GP9 A;  5CS5 A;  2QJ4 A;  4Z0D A;  4IUA A;  3SRI A;  3SP8 A;  3ZWZ A;  1BHT A;  1YXE A;  5CS3 A;  5EOK A;  5CS1 A;  4APM A;  5I25 A;  5EOD A;  4R1A A;  1HKY A;  2LL4 M;  5CS9 A;  5CT1 A;  5COE A;  2X2Z A;  2YIP A;  3SRJ A;  2J8L A;  4UAO A;  4YIZ A;  5CT3 A; 
#chains in the Genus database with same CATH homology
 2LL3 A;  1W81 A;  2HGF A;  3HN4 A;  2Q8A A;  2Z8V A;  4APL A;  4A5T S;  1Z40 A;  5CT2 A;  5CSQ A;  2J8J A;  3HMR A;  2QJ2 A;  4YIV A;  4Z0E A;  2Z8W A;  4R19 A;  4R1C A;  4R1B A;  2Y8R A;  3HMT A;  2KL5 A;  3HMS A;  5CP9 A;  2YIO A;  3MKP A;  2Q8B A;  4Z0F A;  1NK1 A;  2F83 A;  2K13 X;  4DUR A;  1W8K A;  1GMO A;  2YIL A;  4Z09 A;  1I8N A;  1GMN A;  3ZLE A;  4UV6 A;  1GP9 A;  5CS5 A;  2QJ4 A;  4Z0D A;  4IUA A;  3SRI A;  3SP8 A;  3ZWZ A;  1BHT A;  1YXE A;  5CS3 A;  5EOK A;  5CS1 A;  4APM A;  5I25 A;  5EOD A;  4R1A A;  1HKY A;  2LL4 M;  5CS9 A;  5CT1 A;  5COE A;  2X2Z A;  2YIP A;  3SRJ A;  2J8L A;  4UAO A;  4YIZ A;  5CT3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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