1IAAA

Crystal structures, spectroscopic features, and catalytic properties of cobalt(ii), copper(ii), nickel(ii), and mercury(ii) derivatives of the zinc endopeptidase astacin. a correlation of structure and proteolytic activity
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
200
structure length
200
Chain Sequence
AAILGDEYLWSGGVIPYTFAGVSGADQSAILSGMQELEEKTCIRFVPRTTESDYVEIFTSGSGCWSYVGRISGAQQVSLQANGCVYHGTIIHELMHAIGFYHEHTRMDRDNYVTINYQNVDPSMTSNFDIDTYSRYVGEDYQYYSIMHYGKYSFSIQWGVLETIVPLQNGIDLTDPYDKAHMLQTDANQINNLYTNECSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures, spectroscopic features, and catalytic properties of cobalt(II), copper(II), nickel(II), and mercury(II) derivatives of the zinc endopeptidase astacin. A correlation of structure and proteolytic activity.
pubmed rcsb
molecule tags Zinc endopeptidase
source organism Astacus astacus
molecule keywords ASTACIN
total genus 67
structure length 200
sequence length 200
ec nomenclature ec 3.4.24.21: Astacin.
pdb deposition date 1994-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01400 Astacin Astacin (Peptidase family M12A)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1iaaA00
1UMTA 1R55A 1IAGA 5D1UA 3AYKA 5H8XA 4R3VA 2Y6DA 2KRJA 3AIGA 4PKWA 2JT6A 5LABA 3HB2P 2OXWA 1B8YA 4DF9A 4ON1A 4H49A 3NX7A 1A85A 2XS3A 3L0VA 3KEJA 1HFCA 3ELMA 3F17A 3DPFA 1GO8P 1HOVA 1PWQA 3LJZA 4PKRA 3ZUKA 1KBCA 1D7XA 3LILA 1JAQA 4GUYA 3N2VA 1DTHA 1JJ9A 2PJTA 2W13A 4ZR5A 2OW1A 1ZS0A 4AXQA 5BOYA 1BM6A 1OS2A 4JIJA 2WO9A 4H1QA 1YP1A 2ERQA 1O0TA 1AKLA 4QKZA 1ZXCA 2W12A 2WOAA 4JQGA 1OM6A 4WK7A 1FM1A 1KUKA 5I0LA 1UEAA 3ZXHA 3I7IA 2Z2DA 1C3IA 1XUCA 1CGLA 2Y6CA 1MNCA 3KEKA 3OHOA 1ZTQA 3E8RA 2N8RA 1YQYA 1USNA 1GE5A 2DW0A 1DMTA 3BA0A 3GBOA 3LJGA 3TT4A 4A7BA 3KMCA 1GKDA 830CA 2OY4A 3LIRA 4XM7A 1HY7A 2I47A 3DSLA 1IABA 2DW1A 1KUFA 2OY2A 966CA 1RMZA 2E2DA 1BQOA 2TCLA 4WZVA 1C8TA 1KUHA 3HY9A 1OM8A 1CGFA 2JT5A 4JPAA 2OXUA 4FXYP 2X3AA 4GF1A 4DV8A 4WKIA 3WV3A 3MA2A 5D3CA 1XFXA 2MLSA 3P1VA 1R1HA 3P24A 1G49A 4GR0A 2MLRA 4ILWD 1PWWA 1HV5A 1UMSA 2E3XA 3TVCA 2XS4A 2OI0A 2HU6A 4L6TA 3EDIA 3VI1A 3LMCA 3SHIA 2X3CA 1XFZA 3O2XA 3DNGA 2AYKA 3F1AA 1QICA 3LIKA 3KRYA 1BKCI 1R54A 1A86A 2MZHA 2AIGP 1CK7A 3USNA 2X7MA 3N2UA 1Y93A 3EHYA 5I2ZA 2OW0A 3HDAP 2J0TA 2JNPA 4XM6A 1QIBA 1UTZA 1WNIA 1AF0A 4Q1LA 1D8MA 4A3WA 1CGEA 3OHLA 3EDZA 1S4BP 1BQQM 2USNA 1CAQA 1XFVA 1JK3A 1GKCA 2RJQA 2O3EA 2OW2A 1GE7A 2L0RA 3EDGA 3V96B 1JKYA 3Q2HA 1CXVA 1BIWA 5B5PA 1EAKA 4GR3A 1UTTA 3LQBA 4HMAA 1ROSA 1JH1A 1G4KA 1HFSA 4GWMA 5CXAA 2X3BA 1Z3JA 1C7KA 1QIAA 1L6JA 1G9KA 3EHXA 3G5CA 3LUNA 3K7LA 1ZP5A 1KUIA 3RTTA 4I35A 3O64A 1K7IA 3LJTA 3DPEA 1BKCA 2CLTA 4PKQA 1I76A 1I73A 1BUDA 3EDHA 1KUGA 2O36A 3F15A 3LQ0A 2J83A 1FBLA 1GE6A 1YOUA 1QJJA 3LK8A 3K7NA 4XM8A 3B2ZA 4AYKA 5I12A 1IAAA 2JIHA 3LKAA 4FXQA 3F18A 2V4BA 3Q2GA 1EB6A 2ERPA 2YIGA 4H2EA 3HY7A 1JANA 1JIZA 1IADA 2OZRA 4H3XA 1CQRA 3LUMA 3KWVC 1ASTA 1SATA 2W14A 4PKTA 1AYKA 2OW9A 1H71P 4DD8A 4EFSA 3DL1A 1Y8JA 1RM8A 1ATLA 1ND1A 3ZVSA 1SU3A 3WV1A 1OM7A 5L7FA 2MZIA 1JIWP 1D5JA 2DDFA 3I7GA 4AIGA 1G05A 1XURA 2W15A 5CUHA 2POJA 3G42A 3KHIA 3U1RA 1MMPA 1SRPA 4PKSA 2FV5A 3CKIA 3KECA 1SLMA 1QUAA 3HBUP 3F19A 3KMEA 2WO8A 1OMJA 4DPEA 1MMQA 1YCMA 2QPJA 1KAPP 3VTGA 2RJPA 4H30A 5D1SA 5D7WA 1JAPA 2FV9A 4H84A 4IUWA 4PKUA 2D1NA 1R1IA 3B8ZA 5I3MA 3TSKA 1GO7P 3L0TA 2OVZA 3LEAA 5JMYA 1OO9A 1PWUA 5D1TA 4XCTA 2A8HA 2EROA 4FVLA 3AYUA 1XFYA 3HDBA 4FU4A 4PKVA 4AUOA 1GXDA 1O0QA 2DW2A 2SRTA 4GR8A 1BZSA 3UVCA 3HBVP 1QJIA 1JAOA 4CTHA 1BKCE 4IJOA 3B92A 4XBHA 3F16A 3DWBA 4L63A 3LGPA 3HYGA 4L19A 4JP4A 2OVXA 1I1IP 5D2BA 2DDYA 3WV2A 2W0DA 4HX3A 2YB9A 1BSWA 1PWPA 1XFUA 1ZXVA 4G9LA 1D8FA 1Y0VA 2K9CA 5I4OA 2K2GA 4GWNA 1IACA 5BPAA 4WF6A 1FLSA 4IN9A 1XFWA 3EWJA 3TS4A 5B5OA 2D1OA 1J7NA 1CIZA 4WKEA 1R1JA 1MMBA 1PWVA 1ZVXA 1XUDA 1K7QA 4H82A 4J4MA 1OS9A 4H76A 1B3DA 5I43A 1Q3AA 1BUVM 1G12A 5CZMA 2MZEA 456CA 1IAEA 1MMRA 2CKIA 2JSDA 4JA1A 1HTDA 1K7GA 4I03A 3LE9A 1SLNA 4GQLA 5BOTA 4G0DA 1EUBA 3RTSA 2OXZA 1SMPA 5L79A
chains in the Genus database with same CATH superfamily
1UMTA 1R55A 1IAGA 5D1UA 3AYKA 5H8XA 4R3VA 2Y6DA 2KRJA 3AIGA 4PKWA 2JT6A 5LABA 3HB2P 1XAXA 1B8YA 2OXWA 4DF9A 4ON1A 4H49A 3NX7A 1A85A 2XS3A 3L0VA 3KEJA 1HFCA 3ELMA 3F17A 3DPFA 1GO8P 1HOVA 1PWQA 3LJZA 4PKRA 3ZUKA 1KBCA 1D7XA 3LILA 1JAQA 4GUYA 1XM5A 3N2VA 1DTHA 1JJ9A 2PJTA 2W13A 4ZR5A 2OW1A 1ZS0A 4AXQA 5BOYA 1BM6A 1OS2A 4JIJA 2WO9A 4H1QA 1YP1A 2ERQA 1O0TA 1AKLA 4QKZA 1ZXCA 2W12A 2WOAA 4JQGA 1OM6A 4WK7A 1FM1A 1KUKA 5I0LA 1UEAA 3ZXHA 3I7IA 2Z2DA 1C3IA 1XUCA 1CGLA 2Y6CA 1MNCA 3KEKA 3OHOA 1ZTQA 3E8RA 2N8RA 1YQYA 1USNA 1GE5A 2DW0A 1DMTA 3BA0A 3GBOA 3LJGA 3TT4A 4A7BA 3KMCA 3DTIA 1GKDA 830CA 2OY4A 3LIRA 4XM7A 1HY7A 2I47A 3DSLA 1IABA 2DW1A 1KUFA 2OY2A 966CA 1RMZA 2E2DA 1BQOA 2TCLA 4WZVA 1C8TA 1KUHA 3HY9A 1OM8A 1CGFA 2JT5A 4JPAA 2OXUA 4FXYP 2X3AA 4GF1A 4DV8A 4WKIA 3WV3A 3MA2A 5D3CA 1XFXA 2MLSA 3P1VA 1R1HA 3P24A 1G49A 4GR0A 2MLRA 4ILWD 1PWWA 1HV5A 1UMSA 2E3XA 3TVCA 2XS4A 2OI0A 2HU6A 4L6TA 3EDIA 3VI1A 3LMCA 3SHIA 2X3CA 1XFZA 3O2XA 3DNGA 2AYKA 3F1AA 1QICA 3LIKA 3KRYA 1BKCI 1R54A 1A86A 2MZHA 2AIGP 1CK7A 3USNA 2X7MA 3N2UA 1Y93A 3EHYA 5I2ZA 2OW0A 3HDAP 2J0TA 2JNPA 4XM6A 1QIBA 1UTZA 1WNIA 1AF0A 4Q1LA 1D8MA 4A3WA 3DTKA 1CGEA 3OHLA 3EDZA 1S4BP 1BQQM 2USNA 1CAQA 1XFVA 1JK3A 1GKCA 2RJQA 2O3EA 2OW2A 1GE7A 2L0RA 3EDGA 3V96B 1JKYA 3Q2HA 1CXVA 1BIWA 5B5PA 1EAKA 4GR3A 1UTTA 3LQBA 4HMAA 1ROSA 1JH1A 1G4KA 1HFSA 4GWMA 5CXAA 2X3BA 1Z3JA 1C7KA 1QIAA 1L6JA 1G9KA 3EHXA 3G5CA 3LUNA 3K7LA 1ZP5A 1KUIA 3RTTA 4I35A 3O64A 1K7IA 3LJTA 3DPEA 1BKCA 2CLTA 4PKQA 1I76A 1I73A 1BUDA 3EDHA 1KUGA 2O36A 3F15A 3LQ0A 2J83A 1FBLA 1GE6A 1YOUA 1QJJA 3LK8A 3K7NA 4XM8A 3B2ZA 4AYKA 5I12A 1IAAA 2JIHA 3LKAA 4FXQA 3F18A 2V4BA 3Q2GA 1EB6A 2ERPA 2YIGA 4H2EA 3HY7A 1JANA 1JIZA 1IADA 2OZRA 4H3XA 1CQRA 3LUMA 3KWVC 1ASTA 1SATA 2W14A 4PKTA 1AYKA 2OW9A 1H71P 1OZ9A 4DD8A 4EFSA 3DL1A 1Y8JA 1RM8A 1ATLA 1ND1A 3ZVSA 1SU3A 3WV1A 1OM7A 5L7FA 2MZIA 1JIWP 1D5JA 2DDFA 3I7GA 4AIGA 1G05A 1XURA 2W15A 5CUHA 2POJA 3G42A 3KHIA 3U1RA 4L7AA 1MMPA 1SRPA 4PKSA 2FV5A 3CKIA 3KECA 1SLMA 1QUAA 1TVIA 3HBUP 3F19A 3KMEA 2WO8A 1OMJA 4DPEA 1MMQA 1YCMA 2QPJA 1KAPP 3VTGA 2RJPA 4H30A 5D1SA 5D7WA 1JAPA 2FV9A 4H84A 4IUWA 4PKUA 2D1NA 1R1IA 3B8ZA 5I3MA 3TSKA 1GO7P 3L0TA 2OVZA 3LEAA 5JMYA 1OO9A 1PWUA 5D1TA 4XCTA 2A8HA 2EROA 4FVLA 3AYUA 1XFYA 3HDBA 4FU4A 4PKVA 4AUOA 1GXDA 1O0QA 2DW2A 2SRTA 4GR8A 1BZSA 3UVCA 2YUFA 3HBVP 1QJIA 1JAOA 4CTHA 1BKCE 4IJOA 3B92A 4XBHA 3F16A 3DWBA 4L63A 3LGPA 3HYGA 4L19A 4JP4A 2OVXA 1I1IP 5D2BA 2DDYA 3WV2A 2W0DA 4HX3A 2YB9A 1BSWA 1PWPA 1XFUA 1ZXVA 4G9LA 1D8FA 1Y0VA 2K9CA 5I4OA 2K2GA 4GWNA 1IACA 5BPAA 4WF6A 1FLSA 4IN9A 1XFWA 3EWJA 3TS4A 5B5OA 2D1OA 1J7NA 1CIZA 4WKEA 1R1JA 1MMBA 1PWVA 1ZVXA 1XUDA 1K7QA 4H82A 4J4MA 1OS9A 3DTEA 4H76A 1B3DA 5I43A 1Q3AA 1BUVM 1G12A 5CZMA 2MZEA 456CA 1IAEA 1MMRA 2CKIA 2JSDA 4JA1A 1HTDA 1K7GA 4I03A 3LE9A 1SLNA 4GQLA 5BOTA 4G0DA 1EUBA 3RTSA 2OXZA 1SMPA 5L79A
chains in the Genus database with same CATH topology
1UMTA 1R55A 1IAGA 5D1UA 3AYKA 5H8XA 4R3VA 2Y6DA 2KRJA 3AIGA 4PKWA 2JT6A 5LABA 3HB2P 2OXWA 1B8YA 4DF9A 4ON1A 4H49A 3NX7A 1A85A 2XS3A 3L0VA 3KEJA 1HFCA 3ELMA 3F17A 3DPFA 1GO8P 1HOVA 1PWQA 3LJZA 4PKRA 3ZUKA 1KBCA 1D7XA 3LILA 1JAQA 4GUYA 3N2VA 1DTHA 1JJ9A 2PJTA 2W13A 4ZR5A 2OW1A 1ZS0A 4AXQA 5BOYA 1BM6A 1OS2A 4JIJA 2WO9A 4H1QA 1YP1A 2ERQA 1O0TA 1AKLA 4QKZA 1ZXCA 2W12A 2WOAA 4JQGA 1OM6A 4WK7A 1FM1A 1KUKA 5I0LA 1UEAA 3ZXHA 3I7IA 2Z2DA 1C3IA 1XUCA 1CGLA 2Y6CA 1MNCA 3KEKA 3OHOA 1ZTQA 3E8RA 2N8RA 1YQYA 1USNA 1GE5A 2DW0A 1DMTA 3BA0A 3GBOA 3LJGA 3TT4A 4A7BA 3KMCA 3DTIA 1GKDA 830CA 2OY4A 3LIRA 4XM7A 1HY7A 2I47A 3DSLA 1IABA 2DW1A 1KUFA 2OY2A 966CA 1RMZA 2E2DA 1BQOA 2TCLA 4WZVA 1C8TA 1KUHA 3HY9A 1OM8A 1CGFA 2JT5A 4JPAA 2OXUA 4FXYP 2X3AA 4GF1A 4DV8A 4WKIA 3WV3A 3MA2A 5D3CA 1XFXA 2MLSA 3P1VA 1R1HA 3P24A 1G49A 4GR0A 2MLRA 4ILWD 1PWWA 1HV5A 1UMSA 2E3XA 3TVCA 2XS4A 2OI0A 2HU6A 4L6TA 3EDIA 3VI1A 3LMCA 3SHIA 2X3CA 1XFZA 3O2XA 3DNGA 2AYKA 3F1AA 1QICA 3LIKA 3KRYA 1BKCI 1R54A 1A86A 2MZHA 2AIGP 1CK7A 3USNA 2X7MA 3N2UA 1Y93A 3EHYA 5I2ZA 2OW0A 3HDAP 2J0TA 2JNPA 4XM6A 1QIBA 1UTZA 1WNIA 1AF0A 4Q1LA 1D8MA 4A3WA 3DTKA 1CGEA 3OHLA 3EDZA 1S4BP 1BQQM 2USNA 1CAQA 1XFVA 1JK3A 1GKCA 2RJQA 2O3EA 2OW2A 1GE7A 2L0RA 3EDGA 3V96B 1JKYA 3Q2HA 1CXVA 1BIWA 5B5PA 1EAKA 4GR3A 1UTTA 3LQBA 4HMAA 1ROSA 1JH1A 1G4KA 1HFSA 4GWMA 5CXAA 2X3BA 1Z3JA 1C7KA 1QIAA 1L6JA 1G9KA 3EHXA 3G5CA 3LUNA 3K7LA 1ZP5A 1KUIA 3RTTA 4I35A 3O64A 1K7IA 3LJTA 3DPEA 1BKCA 2CLTA 4PKQA 1I76A 1I73A 1BUDA 3EDHA 1KUGA 2O36A 3F15A 3LQ0A 2J83A 1FBLA 1GE6A 1YOUA 1QJJA 3LK8A 3K7NA 4XM8A 3B2ZA 4AYKA 5I12A 1IAAA 2JIHA 3LKAA 4FXQA 3F18A 2V4BA 3Q2GA 1EB6A 2ERPA 2YIGA 4H2EA 3HY7A 1JANA 1JIZA 1IADA 2OZRA 4H3XA 1CQRA 3LUMA 3KWVC 1ASTA 1SATA 2W14A 4PKTA 1AYKA 2OW9A 1H71P 4DD8A 4EFSA 3DL1A 1Y8JA 1RM8A 1ATLA 1ND1A 3ZVSA 1SU3A 3WV1A 1OM7A 5L7FA 2MZIA 1JIWP 1D5JA 2DDFA 3I7GA 4AIGA 1G05A 1XURA 2W15A 5CUHA 2POJA 3G42A 3KHIA 3U1RA 4L7AA 1MMPA 1SRPA 4PKSA 2FV5A 3CKIA 3KECA 1SLMA 1QUAA 3HBUP 3F19A 3KMEA 2WO8A 1OMJA 4DPEA 1MMQA 1YCMA 2QPJA 1KAPP 3VTGA 2RJPA 4H30A 5D1SA 5D7WA 1JAPA 2FV9A 4H84A 4IUWA 4PKUA 2D1NA 1R1IA 3B8ZA 5I3MA 3TSKA 1GO7P 3L0TA 2OVZA 3LEAA 5JMYA 1OO9A 1PWUA 5D1TA 4XCTA 2A8HA 2EROA 4FVLA 3AYUA 1XFYA 3HDBA 4FU4A 4PKVA 4AUOA 1GXDA 1O0QA 2DW2A 2SRTA 4GR8A 1BZSA 3UVCA 2YUFA 3HBVP 1QJIA 1JAOA 4CTHA 1BKCE 4IJOA 3B92A 4XBHA 3F16A 3DWBA 4L63A 3LGPA 3HYGA 4L19A 4JP4A 2OVXA 1I1IP 5D2BA 2DDYA 3WV2A 2W0DA 4HX3A 2YB9A 1BSWA 1PWPA 1XFUA 1ZXVA 4G9LA 1D8FA 1Y0VA 2K9CA 5I4OA 2K2GA 4GWNA 1IACA 5BPAA 4WF6A 1FLSA 4IN9A 1XFWA 3EWJA 3TS4A 5B5OA 2D1OA 1J7NA 1CIZA 4WKEA 1R1JA 1MMBA 1PWVA 1ZVXA 1XUDA 1K7QA 4H82A 4J4MA 1OS9A 3DTEA 4H76A 1B3DA 5I43A 1Q3AA 1BUVM 1G12A 5CZMA 2MZEA 456CA 1IAEA 1MMRA 2CKIA 2JSDA 4JA1A 1HTDA 1K7GA 4I03A 3LE9A 1SLNA 4GQLA 5BOTA 4G0DA 1EUBA 3RTSA 2OXZA 1SMPA 5L79A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UMT A;  1R55 A;  1IAG A;  5D1U A;  3AYK A;  5H8X A;  4R3V A;  2Y6D A;  2KRJ A;  3AIG A;  4PKW A;  2JT6 A;  5LAB A;  3HB2 P;  2OXW A;  1B8Y A;  4DF9 A;  4ON1 A;  4H49 A;  3NX7 A;  1A85 A;  2XS3 A;  3L0V A;  3KEJ A;  1HFC A;  3ELM A;  3F17 A;  3DPF A;  1GO8 P;  1HOV A;  1PWQ A;  3LJZ A;  4PKR A;  3ZUK A;  1KBC A;  1D7X A;  3LIL A;  1JAQ A;  4GUY A;  3N2V A;  1DTH A;  1JJ9 A;  2PJT A;  2W13 A;  4ZR5 A;  2OW1 A;  1ZS0 A;  4AXQ A;  5BOY A;  1BM6 A;  1OS2 A;  4JIJ A;  2WO9 A;  4H1Q A;  1YP1 A;  2ERQ A;  1O0T A;  1AKL A;  4QKZ A;  1ZXC A;  2W12 A;  2WOA A;  4JQG A;  1OM6 A;  4WK7 A;  1FM1 A;  1KUK A;  5I0L A;  1UEA A;  3ZXH A;  3I7I A;  2Z2D A;  1C3I A;  1XUC A;  1CGL A;  2Y6C A;  1MNC A;  3KEK A;  3OHO A;  1ZTQ A;  3E8R A;  2N8R A;  1YQY A;  1USN A;  1GE5 A;  2DW0 A;  1DMT A;  3BA0 A;  3GBO A;  3LJG A;  3TT4 A;  4A7B A;  3KMC A;  1GKD A;  830C A;  2OY4 A;  3LIR A;  4XM7 A;  1HY7 A;  2I47 A;  3DSL A;  1IAB A;  2DW1 A;  1KUF A;  2OY2 A;  966C A;  1RMZ A;  2E2D A;  1BQO A;  2TCL A;  4WZV A;  1C8T A;  1KUH A;  3HY9 A;  1OM8 A;  1CGF A;  2JT5 A;  4JPA A;  2OXU A;  4FXY P;  2X3A A;  4GF1 A;  4DV8 A;  4WKI A;  3WV3 A;  3MA2 A;  5D3C A;  1XFX A;  2MLS A;  3P1V A;  1R1H A;  3P24 A;  1G49 A;  4GR0 A;  2MLR A;  4ILW D;  1PWW A;  1HV5 A;  1UMS A;  2E3X A;  3TVC A;  2XS4 A;  2OI0 A;  2HU6 A;  4L6T A;  3EDI A;  3VI1 A;  3LMC A;  3SHI A;  2X3C A;  1XFZ A;  3O2X A;  3DNG A;  2AYK A;  3F1A A;  1QIC A;  3LIK A;  3KRY A;  1BKC I;  1R54 A;  1A86 A;  2MZH A;  2AIG P;  1CK7 A;  3USN A;  2X7M A;  3N2U A;  1Y93 A;  3EHY A;  5I2Z A;  2OW0 A;  3HDA P;  2J0T A;  2JNP A;  4XM6 A;  1QIB A;  1UTZ A;  1WNI A;  1AF0 A;  4Q1L A;  1D8M A;  4A3W A;  1CGE A;  3OHL A;  3EDZ A;  1S4B P;  1BQQ M;  2USN A;  1CAQ A;  1XFV A;  1JK3 A;  1GKC A;  2RJQ A;  2O3E A;  2OW2 A;  1GE7 A;  2L0R A;  3EDG A;  3V96 B;  1JKY A;  3Q2H A;  1CXV A;  1BIW A;  5B5P A;  1EAK A;  4GR3 A;  1UTT A;  3LQB A;  4HMA A;  1ROS A;  1JH1 A;  1G4K A;  1HFS A;  4GWM A;  5CXA A;  2X3B A;  1Z3J A;  1C7K A;  1QIA A;  1L6J A;  1G9K A;  3EHX A;  3G5C A;  3LUN A;  3K7L A;  1ZP5 A;  1KUI A;  3RTT A;  4I35 A;  3O64 A;  1K7I A;  3LJT A;  3DPE A;  1BKC A;  2CLT A;  4PKQ A;  1I76 A;  1I73 A;  1BUD A;  3EDH A;  1KUG A;  2O36 A;  3F15 A;  3LQ0 A;  2J83 A;  1FBL A;  1GE6 A;  1YOU A;  1QJJ A;  3LK8 A;  3K7N A;  4XM8 A;  3B2Z A;  4AYK A;  5I12 A;  1IAA A;  2JIH A;  3LKA A;  4FXQ A;  3F18 A;  2V4B A;  3Q2G A;  1EB6 A;  2ERP A;  2YIG A;  4H2E A;  3HY7 A;  1JAN A;  1JIZ A;  1IAD A;  2OZR A;  4H3X A;  1CQR A;  3LUM A;  3KWV C;  1AST A;  1SAT A;  2W14 A;  4PKT A;  1AYK A;  2OW9 A;  1H71 P;  4DD8 A;  4EFS A;  3DL1 A;  1Y8J A;  1RM8 A;  1ATL A;  1ND1 A;  3ZVS A;  1SU3 A;  3WV1 A;  1OM7 A;  5L7F A;  2MZI A;  1JIW P;  1D5J A;  2DDF A;  3I7G A;  4AIG A;  1G05 A;  1XUR A;  2W15 A;  5CUH A;  2POJ A;  3G42 A;  3KHI A;  3U1R A;  1MMP A;  1SRP A;  4PKS A;  2FV5 A;  3CKI A;  3KEC A;  1SLM A;  1QUA A;  3HBU P;  3F19 A;  3KME A;  2WO8 A;  1OMJ A;  4DPE A;  1MMQ A;  1YCM A;  2QPJ A;  1KAP P;  3VTG A;  2RJP A;  4H30 A;  5D1S A;  5D7W A;  1JAP A;  2FV9 A;  4H84 A;  4IUW A;  4PKU A;  2D1N A;  1R1I A;  3B8Z A;  5I3M A;  3TSK A;  1GO7 P;  3L0T A;  2OVZ A;  3LEA A;  5JMY A;  1OO9 A;  1PWU A;  5D1T A;  4XCT A;  2A8H A;  2ERO A;  4FVL A;  3AYU A;  1XFY A;  3HDB A;  4FU4 A;  4PKV A;  4AUO A;  1GXD A;  1O0Q A;  2DW2 A;  2SRT A;  4GR8 A;  1BZS A;  3UVC A;  3HBV P;  1QJI A;  1JAO A;  4CTH A;  1BKC E;  4IJO A;  3B92 A;  4XBH A;  3F16 A;  3DWB A;  4L63 A;  3LGP A;  3HYG A;  4L19 A;  4JP4 A;  2OVX A;  1I1I P;  5D2B A;  2DDY A;  3WV2 A;  2W0D A;  4HX3 A;  2YB9 A;  1BSW A;  1PWP A;  1XFU A;  1ZXV A;  4G9L A;  1D8F A;  1Y0V A;  2K9C A;  5I4O A;  2K2G A;  4GWN A;  1IAC A;  5BPA A;  4WF6 A;  1FLS A;  4IN9 A;  1XFW A;  3EWJ A;  3TS4 A;  5B5O A;  2D1O A;  1J7N A;  1CIZ A;  4WKE A;  1R1J A;  1MMB A;  1PWV A;  1ZVX A;  1XUD A;  1K7Q A;  4H82 A;  4J4M A;  1OS9 A;  4H76 A;  1B3D A;  5I43 A;  1Q3A A;  1BUV M;  1G12 A;  5CZM A;  2MZE A;  456C A;  1IAE A;  1MMR A;  2CKI A;  2JSD A;  4JA1 A;  1HTD A;  1K7G A;  4I03 A;  3LE9 A;  1SLN A;  4GQL A;  5BOT A;  4G0D A;  1EUB A;  3RTS A;  2OXZ A;  1SMP A;  5L79 A; 
#chains in the Genus database with same CATH topology
 1UMT A;  1R55 A;  1IAG A;  5D1U A;  3AYK A;  5H8X A;  4R3V A;  2Y6D A;  2KRJ A;  3AIG A;  4PKW A;  2JT6 A;  5LAB A;  3HB2 P;  1XAX A;  1B8Y A;  2OXW A;  4DF9 A;  4ON1 A;  4H49 A;  3NX7 A;  1A85 A;  2XS3 A;  3L0V A;  3KEJ A;  1HFC A;  3ELM A;  3F17 A;  3DPF A;  1GO8 P;  1HOV A;  1PWQ A;  3LJZ A;  4PKR A;  3ZUK A;  1KBC A;  1D7X A;  3LIL A;  1JAQ A;  4GUY A;  1XM5 A;  3N2V A;  1DTH A;  1JJ9 A;  2PJT A;  2W13 A;  4ZR5 A;  2OW1 A;  1ZS0 A;  4AXQ A;  5BOY A;  1BM6 A;  1OS2 A;  4JIJ A;  2WO9 A;  4H1Q A;  1YP1 A;  2ERQ A;  1O0T A;  1AKL A;  4QKZ A;  1ZXC A;  2W12 A;  2WOA A;  4JQG A;  1OM6 A;  4WK7 A;  1FM1 A;  1KUK A;  5I0L A;  1UEA A;  3ZXH A;  3I7I A;  2Z2D A;  1C3I A;  1XUC A;  1CGL A;  2Y6C A;  1MNC A;  3KEK A;  3OHO A;  1ZTQ A;  3E8R A;  2N8R A;  1YQY A;  1USN A;  1GE5 A;  2DW0 A;  1DMT A;  3BA0 A;  3GBO A;  3LJG A;  3TT4 A;  4A7B A;  3KMC A;  3DTI A;  1GKD A;  830C A;  2OY4 A;  3LIR A;  4XM7 A;  1HY7 A;  2I47 A;  3DSL A;  1IAB A;  2DW1 A;  1KUF A;  2OY2 A;  966C A;  1RMZ A;  2E2D A;  1BQO A;  2TCL A;  4WZV A;  1C8T A;  1KUH A;  3HY9 A;  1OM8 A;  1CGF A;  2JT5 A;  4JPA A;  2OXU A;  4FXY P;  2X3A A;  4GF1 A;  4DV8 A;  4WKI A;  3WV3 A;  3MA2 A;  5D3C A;  1XFX A;  2MLS A;  3P1V A;  1R1H A;  3P24 A;  1G49 A;  4GR0 A;  2MLR A;  4ILW D;  1PWW A;  1HV5 A;  1UMS A;  2E3X A;  3TVC A;  2XS4 A;  2OI0 A;  2HU6 A;  4L6T A;  3EDI A;  3VI1 A;  3LMC A;  3SHI A;  2X3C A;  1XFZ A;  3O2X A;  3DNG A;  2AYK A;  3F1A A;  1QIC A;  3LIK A;  3KRY A;  1BKC I;  1R54 A;  1A86 A;  2MZH A;  2AIG P;  1CK7 A;  3USN A;  2X7M A;  3N2U A;  1Y93 A;  3EHY A;  5I2Z A;  2OW0 A;  3HDA P;  2J0T A;  2JNP A;  4XM6 A;  1QIB A;  1UTZ A;  1WNI A;  1AF0 A;  4Q1L A;  1D8M A;  4A3W A;  3DTK A;  1CGE A;  3OHL A;  3EDZ A;  1S4B P;  1BQQ M;  2USN A;  1CAQ A;  1XFV A;  1JK3 A;  1GKC A;  2RJQ A;  2O3E A;  2OW2 A;  1GE7 A;  2L0R A;  3EDG A;  3V96 B;  1JKY A;  3Q2H A;  1CXV A;  1BIW A;  5B5P A;  1EAK A;  4GR3 A;  1UTT A;  3LQB A;  4HMA A;  1ROS A;  1JH1 A;  1G4K A;  1HFS A;  4GWM A;  5CXA A;  2X3B A;  1Z3J A;  1C7K A;  1QIA A;  1L6J A;  1G9K A;  3EHX A;  3G5C A;  3LUN A;  3K7L A;  1ZP5 A;  1KUI A;  3RTT A;  4I35 A;  3O64 A;  1K7I A;  3LJT A;  3DPE A;  1BKC A;  2CLT A;  4PKQ A;  1I76 A;  1I73 A;  1BUD A;  3EDH A;  1KUG A;  2O36 A;  3F15 A;  3LQ0 A;  2J83 A;  1FBL A;  1GE6 A;  1YOU A;  1QJJ A;  3LK8 A;  3K7N A;  4XM8 A;  3B2Z A;  4AYK A;  5I12 A;  1IAA A;  2JIH A;  3LKA A;  4FXQ A;  3F18 A;  2V4B A;  3Q2G A;  1EB6 A;  2ERP A;  2YIG A;  4H2E A;  3HY7 A;  1JAN A;  1JIZ A;  1IAD A;  2OZR A;  4H3X A;  1CQR A;  3LUM A;  3KWV C;  1AST A;  1SAT A;  2W14 A;  4PKT A;  1AYK A;  2OW9 A;  1H71 P;  1OZ9 A;  4DD8 A;  4EFS A;  3DL1 A;  1Y8J A;  1RM8 A;  1ATL A;  1ND1 A;  3ZVS A;  1SU3 A;  3WV1 A;  1OM7 A;  5L7F A;  2MZI A;  1JIW P;  1D5J A;  2DDF A;  3I7G A;  4AIG A;  1G05 A;  1XUR A;  2W15 A;  5CUH A;  2POJ A;  3G42 A;  3KHI A;  3U1R A;  4L7A A;  1MMP A;  1SRP A;  4PKS A;  2FV5 A;  3CKI A;  3KEC A;  1SLM A;  1QUA A;  1TVI A;  3HBU P;  3F19 A;  3KME A;  2WO8 A;  1OMJ A;  4DPE A;  1MMQ A;  1YCM A;  2QPJ A;  1KAP P;  3VTG A;  2RJP A;  4H30 A;  5D1S A;  5D7W A;  1JAP A;  2FV9 A;  4H84 A;  4IUW A;  4PKU A;  2D1N A;  1R1I A;  3B8Z A;  5I3M A;  3TSK A;  1GO7 P;  3L0T A;  2OVZ A;  3LEA A;  5JMY A;  1OO9 A;  1PWU A;  5D1T A;  4XCT A;  2A8H A;  2ERO A;  4FVL A;  3AYU A;  1XFY A;  3HDB A;  4FU4 A;  4PKV A;  4AUO A;  1GXD A;  1O0Q A;  2DW2 A;  2SRT A;  4GR8 A;  1BZS A;  3UVC A;  2YUF A;  3HBV P;  1QJI A;  1JAO A;  4CTH A;  1BKC E;  4IJO A;  3B92 A;  4XBH A;  3F16 A;  3DWB A;  4L63 A;  3LGP A;  3HYG A;  4L19 A;  4JP4 A;  2OVX A;  1I1I P;  5D2B A;  2DDY A;  3WV2 A;  2W0D A;  4HX3 A;  2YB9 A;  1BSW A;  1PWP A;  1XFU A;  1ZXV A;  4G9L A;  1D8F A;  1Y0V A;  2K9C A;  5I4O A;  2K2G A;  4GWN A;  1IAC A;  5BPA A;  4WF6 A;  1FLS A;  4IN9 A;  1XFW A;  3EWJ A;  3TS4 A;  5B5O A;  2D1O A;  1J7N A;  1CIZ A;  4WKE A;  1R1J A;  1MMB A;  1PWV A;  1ZVX A;  1XUD A;  1K7Q A;  4H82 A;  4J4M A;  1OS9 A;  3DTE A;  4H76 A;  1B3D A;  5I43 A;  1Q3A A;  1BUV M;  1G12 A;  5CZM A;  2MZE A;  456C A;  1IAE A;  1MMR A;  2CKI A;  2JSD A;  4JA1 A;  1HTD A;  1K7G A;  4I03 A;  3LE9 A;  1SLN A;  4GQL A;  5BOT A;  4G0D A;  1EUB A;  3RTS A;  2OXZ A;  1SMP A;  5L79 A; 
#chains in the Genus database with same CATH homology
 1UMT A;  1R55 A;  1IAG A;  5D1U A;  3AYK A;  5H8X A;  4R3V A;  2Y6D A;  2KRJ A;  3AIG A;  4PKW A;  2JT6 A;  5LAB A;  3HB2 P;  2OXW A;  1B8Y A;  4DF9 A;  4ON1 A;  4H49 A;  3NX7 A;  1A85 A;  2XS3 A;  3L0V A;  3KEJ A;  1HFC A;  3ELM A;  3F17 A;  3DPF A;  1GO8 P;  1HOV A;  1PWQ A;  3LJZ A;  4PKR A;  3ZUK A;  1KBC A;  1D7X A;  3LIL A;  1JAQ A;  4GUY A;  3N2V A;  1DTH A;  1JJ9 A;  2PJT A;  2W13 A;  4ZR5 A;  2OW1 A;  1ZS0 A;  4AXQ A;  5BOY A;  1BM6 A;  1OS2 A;  4JIJ A;  2WO9 A;  4H1Q A;  1YP1 A;  2ERQ A;  1O0T A;  1AKL A;  4QKZ A;  1ZXC A;  2W12 A;  2WOA A;  4JQG A;  1OM6 A;  4WK7 A;  1FM1 A;  1KUK A;  5I0L A;  1UEA A;  3ZXH A;  3I7I A;  2Z2D A;  1C3I A;  1XUC A;  1CGL A;  2Y6C A;  1MNC A;  3KEK A;  3OHO A;  1ZTQ A;  3E8R A;  2N8R A;  1YQY A;  1USN A;  1GE5 A;  2DW0 A;  1DMT A;  3BA0 A;  3GBO A;  3LJG A;  3TT4 A;  4A7B A;  3KMC A;  3DTI A;  1GKD A;  830C A;  2OY4 A;  3LIR A;  4XM7 A;  1HY7 A;  2I47 A;  3DSL A;  1IAB A;  2DW1 A;  1KUF A;  2OY2 A;  966C A;  1RMZ A;  2E2D A;  1BQO A;  2TCL A;  4WZV A;  1C8T A;  1KUH A;  3HY9 A;  1OM8 A;  1CGF A;  2JT5 A;  4JPA A;  2OXU A;  4FXY P;  2X3A A;  4GF1 A;  4DV8 A;  4WKI A;  3WV3 A;  3MA2 A;  5D3C A;  1XFX A;  2MLS A;  3P1V A;  1R1H A;  3P24 A;  1G49 A;  4GR0 A;  2MLR A;  4ILW D;  1PWW A;  1HV5 A;  1UMS A;  2E3X A;  3TVC A;  2XS4 A;  2OI0 A;  2HU6 A;  4L6T A;  3EDI A;  3VI1 A;  3LMC A;  3SHI A;  2X3C A;  1XFZ A;  3O2X A;  3DNG A;  2AYK A;  3F1A A;  1QIC A;  3LIK A;  3KRY A;  1BKC I;  1R54 A;  1A86 A;  2MZH A;  2AIG P;  1CK7 A;  3USN A;  2X7M A;  3N2U A;  1Y93 A;  3EHY A;  5I2Z A;  2OW0 A;  3HDA P;  2J0T A;  2JNP A;  4XM6 A;  1QIB A;  1UTZ A;  1WNI A;  1AF0 A;  4Q1L A;  1D8M A;  4A3W A;  3DTK A;  1CGE A;  3OHL A;  3EDZ A;  1S4B P;  1BQQ M;  2USN A;  1CAQ A;  1XFV A;  1JK3 A;  1GKC A;  2RJQ A;  2O3E A;  2OW2 A;  1GE7 A;  2L0R A;  3EDG A;  3V96 B;  1JKY A;  3Q2H A;  1CXV A;  1BIW A;  5B5P A;  1EAK A;  4GR3 A;  1UTT A;  3LQB A;  4HMA A;  1ROS A;  1JH1 A;  1G4K A;  1HFS A;  4GWM A;  5CXA A;  2X3B A;  1Z3J A;  1C7K A;  1QIA A;  1L6J A;  1G9K A;  3EHX A;  3G5C A;  3LUN A;  3K7L A;  1ZP5 A;  1KUI A;  3RTT A;  4I35 A;  3O64 A;  1K7I A;  3LJT A;  3DPE A;  1BKC A;  2CLT A;  4PKQ A;  1I76 A;  1I73 A;  1BUD A;  3EDH A;  1KUG A;  2O36 A;  3F15 A;  3LQ0 A;  2J83 A;  1FBL A;  1GE6 A;  1YOU A;  1QJJ A;  3LK8 A;  3K7N A;  4XM8 A;  3B2Z A;  4AYK A;  5I12 A;  1IAA A;  2JIH A;  3LKA A;  4FXQ A;  3F18 A;  2V4B A;  3Q2G A;  1EB6 A;  2ERP A;  2YIG A;  4H2E A;  3HY7 A;  1JAN A;  1JIZ A;  1IAD A;  2OZR A;  4H3X A;  1CQR A;  3LUM A;  3KWV C;  1AST A;  1SAT A;  2W14 A;  4PKT A;  1AYK A;  2OW9 A;  1H71 P;  4DD8 A;  4EFS A;  3DL1 A;  1Y8J A;  1RM8 A;  1ATL A;  1ND1 A;  3ZVS A;  1SU3 A;  3WV1 A;  1OM7 A;  5L7F A;  2MZI A;  1JIW P;  1D5J A;  2DDF A;  3I7G A;  4AIG A;  1G05 A;  1XUR A;  2W15 A;  5CUH A;  2POJ A;  3G42 A;  3KHI A;  3U1R A;  4L7A A;  1MMP A;  1SRP A;  4PKS A;  2FV5 A;  3CKI A;  3KEC A;  1SLM A;  1QUA A;  3HBU P;  3F19 A;  3KME A;  2WO8 A;  1OMJ A;  4DPE A;  1MMQ A;  1YCM A;  2QPJ A;  1KAP P;  3VTG A;  2RJP A;  4H30 A;  5D1S A;  5D7W A;  1JAP A;  2FV9 A;  4H84 A;  4IUW A;  4PKU A;  2D1N A;  1R1I A;  3B8Z A;  5I3M A;  3TSK A;  1GO7 P;  3L0T A;  2OVZ A;  3LEA A;  5JMY A;  1OO9 A;  1PWU A;  5D1T A;  4XCT A;  2A8H A;  2ERO A;  4FVL A;  3AYU A;  1XFY A;  3HDB A;  4FU4 A;  4PKV A;  4AUO A;  1GXD A;  1O0Q A;  2DW2 A;  2SRT A;  4GR8 A;  1BZS A;  3UVC A;  2YUF A;  3HBV P;  1QJI A;  1JAO A;  4CTH A;  1BKC E;  4IJO A;  3B92 A;  4XBH A;  3F16 A;  3DWB A;  4L63 A;  3LGP A;  3HYG A;  4L19 A;  4JP4 A;  2OVX A;  1I1I P;  5D2B A;  2DDY A;  3WV2 A;  2W0D A;  4HX3 A;  2YB9 A;  1BSW A;  1PWP A;  1XFU A;  1ZXV A;  4G9L A;  1D8F A;  1Y0V A;  2K9C A;  5I4O A;  2K2G A;  4GWN A;  1IAC A;  5BPA A;  4WF6 A;  1FLS A;  4IN9 A;  1XFW A;  3EWJ A;  3TS4 A;  5B5O A;  2D1O A;  1J7N A;  1CIZ A;  4WKE A;  1R1J A;  1MMB A;  1PWV A;  1ZVX A;  1XUD A;  1K7Q A;  4H82 A;  4J4M A;  1OS9 A;  3DTE A;  4H76 A;  1B3D A;  5I43 A;  1Q3A A;  1BUV M;  1G12 A;  5CZM A;  2MZE A;  456C A;  1IAE A;  1MMR A;  2CKI A;  2JSD A;  4JA1 A;  1HTD A;  1K7G A;  4I03 A;  3LE9 A;  1SLN A;  4GQL A;  5BOT A;  4G0D A;  1EUB A;  3RTS A;  2OXZ A;  1SMP A;  5L79 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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