1IAEA

Crystal structures, spectroscopic features, and catalytic properties of cobalt(ii), copper(ii), nickel(ii), and mercury(ii) derivatives of the zinc endopeptidase astacin. a correlation of structure and proteolytic activity
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
200
structure length
200
Chain Sequence
AAILGDEYLWSGGVIPYTFAGVSGADQSAILSGMQELEEKTCIRFVPRTTESDYVEIFTSGSGCWSYVGRISGAQQVSLQANGCVYHGTIIHELMHAIGFYHEHTRMDRDNYVTINYQNVDPSMTSNFDIDTYSRYVGEDYQYYSIMHYGKYSFSIQWGVLETIVPLQNGIDLTDPYDKAHMLQTDANQINNLYTNECSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures, spectroscopic features, and catalytic properties of cobalt(II), copper(II), nickel(II), and mercury(II) derivatives of the zinc endopeptidase astacin. A correlation of structure and proteolytic activity.
pubmed rcsb
molecule tags Zinc endopeptidase
source organism Astacus astacus
molecule keywords ASTACIN
total genus 67
structure length 200
sequence length 200
ec nomenclature ec 3.4.24.21: Astacin.
pdb deposition date 1994-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01400 Astacin Astacin (Peptidase family M12A)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1iaeA00
3GBOA 3KMEA 1YP1A 4GWMA 4FU4A 4GF1A 2J0TA 3SHIA 5JMYA 1O0TA 1OS9A 2KRJA 2OXZA 3LILA 2DW1A 2E3XA 1DTHA 1FM1A 2JT6A 1R55A 3HB2P 2D1NA 1G05A 1ATLA 2K2GA 1PWQA 1UMTA 2POJA 1OM8A 2Z2DA 1CXVA 1C8TA 2TCLA 3HDAP 3LJZA 3TT4A 1R1JA 1JH1A 4PKQA 966CA 4ZR5A 4XM8A 1EAKA 3OHOA 3L0TA 1QJIA 4A7BA 1GKCA 2FV5A 2J83A 1C7KA 1G49A 3B2ZA 2E2DA 3NX7A 3F18A 1ZS0A 3RTTA 3DNGA 1HV5A 2L0RA 3KECA 2DDFA 4L19A 2JIHA 4Q1LA 1ASTA 4J4MA 4FVLA 5LABA 2X3CA 3RTSA 1K7GA 1JANA 3WV2A 1JIWP 1KUIA 2A8HA 1IAAA 1YCMA 4JQGA 1UEAA 4G9LA 830CA 2K9CA 1JAOA 2D1OA 4FXYP 4GR8A 2CKIA 2X7MA 2CLTA 4H3XA 1ZXVA 1KBCA 4HMAA 1FBLA 4L63A 5D1SA 1BM6A 4PKRA 1A85A 1Y0VA 4AUOA 3B92A 2Y6DA 1G12A 3LMCA 4L6TA 4I03A 4WZVA 3KHIA 2PJTA 2MZHA 1K7IA 4AXQA 3I7GA 3LIRA 2OVXA 1IAGA 2QPJA 1R54A 5D7WA 3HBVP 1KUKA 3F1AA 1IACA 2DW0A 4XCTA 2OY2A 1Q3AA 4QKZA 3LE9A 2ERPA 2OZRA 2OI0A 1OS2A 3EWJA 3EDGA 3N2VA 1YQYA 1ZTQA 3KEJA 4XM6A 1OO9A 3LQ0A 2MLSA 1OMJA 1IABA 1L6JA 1HFCA 4I35A 1OM7A 3Q2GA 2DW2A 4AYKA 2MZEA 1Y93A 2MZIA 3MA2A 3Q2HA 3KEKA 1ND1A 3HYGA 4FXQA 3EDIA 3K7LA 4H2EA 1XURA 1KUHA 5D1TA 5I4OA 1MMBA 4H82A 3AYKA 4EFSA 1ZVXA 1A86A 4JIJA 2X3BA 4H1QA 1QICA 1C3IA 2I47A 1J7NA 4PKUA 3AIGA 1R1IA 1AYKA 5BOYA 1XFVA 3B8ZA 2OW9A 1MMPA 3BA0A 3F19A 3HY9A 1G9KA 2X3AA 4DF9A 5L79A 1JJ9A 5BPAA 1BZSA 1ZP5A 1S4BP 2OW2A 4IJOA 3LKAA 3WV3A 2USNA 1D7XA 1BKCE 1BQQM 1BIWA 2AYKA 1MMRA 1JKYA 3LK8A 3ELMA 1CGFA 1QIBA 1MMQA 4GQLA 5I0LA 2O36A 4DD8A 2OW1A 3USNA 1FLSA 2AIGP 2JT5A 4WKIA 2HU6A 1BUDA 1PWVA 5D2BA 2RJQA 1WNIA 3TS4A 1Z3JA 1CAQA 3EDHA 456CA 1PWWA 3VI1A 5I2ZA 3E8RA 1CK7A 1AKLA 5I12A 1H71P 2XS4A 3G5CA 4A3WA 1D5JA 5I3MA 1BSWA 1D8MA 5B5OA 3AYUA 3O64A 1JAPA 1GE5A 1SATA 1GE7A 3DWBA 1UTZA 1IADA 3HY7A 3ZUKA 4JA1A 1ZXCA 1CQRA 3HDBA 4H30A 4PKWA 2OW0A 3LIKA 1DMTA 1XFUA 5H8XA 1B8YA 1Y8JA 3N2UA 3U1RA 3V96B 5D3CA 4PKTA 3LUMA 1BKCA 3LJGA 4WKEA 2OVZA 3LJTA 3LUNA 2RJPA 3DPFA 1JAQA 1I73A 4GR0A 3P1VA 3F15A 3G42A 4JP4A 4ILWD 2OY4A 4JPAA 1RMZA 1PWPA 3EHXA 1GKDA 2ERQA 1UTTA 3LGPA 1HTDA 1QJJA 1R1HA 4ON1A 1UMSA 3UVCA 1XFXA 2V4BA 1QUAA 2FV9A 4WF6A 3L0VA 1G4KA 1B3DA 3LQBA 1EB6A 3KWVC 5CXAA 3DSLA 3HBUP 2W15A 2YB9A 2MLRA 3EHYA 1GO7P 4HX3A 4H84A 5BOTA 1KUFA 3ZXHA 4PKVA 1JIZA 1SRPA 3P24A 3O2XA 1HFSA 3KRYA 1BQOA 2W14A 4IUWA 1GE6A 1XUCA 4WK7A 5B5PA 5I43A 3DL1A 4PKSA 1EUBA 4GR3A 1SU3A 2JNPA 1HY7A 1HOVA 1KUGA 2SRTA 1IAEA 1XFYA 2WO9A 3EDZA 5L7FA 1SLNA 1RM8A 2JSDA 2XS3A 2YIGA 1XUDA 3WV1A 1MNCA 1XFWA 1YOUA 1OM6A 1XFZA 2OXWA 3TSKA 4G0DA 1GO8P 1D8FA 4AIGA 3F17A 3I7IA 3OHLA 1KAPP 5CUHA 1QIAA 1I1IP 4DV8A 4GUYA 4GWNA 1JK3A 1CGLA 2WO8A 1BKCI 1SLMA 3F16A 2O3EA 4H76A 1SMPA 4XM7A 4DPEA 3ZVSA 3KMCA 2OXUA 3VTGA 4H49A 3LEAA 3K7NA 1I76A 3CKIA 2W12A 2Y6CA 4R3VA 2W13A 1CGEA 4XBHA 3TVCA 2WOAA 3DPEA 2DDYA 1AF0A 1O0QA 1PWUA 4CTHA 1BUVM 2N8RA 1K7QA 1CIZA 4IN9A 1ROSA 2W0DA 5CZMA 5D1UA 2EROA 1GXDA 1USNA
chains in the Genus database with same CATH superfamily
3GBOA 3KMEA 1YP1A 4GWMA 4FU4A 4GF1A 2J0TA 3SHIA 5JMYA 1O0TA 1OS9A 2KRJA 2OXZA 3LILA 2DW1A 2E3XA 1DTHA 1FM1A 2JT6A 1R55A 3HB2P 2D1NA 1G05A 1ATLA 2K2GA 1PWQA 1UMTA 2POJA 1OM8A 2Z2DA 1CXVA 1C8TA 2TCLA 3HDAP 3LJZA 3TT4A 1R1JA 1JH1A 4PKQA 966CA 4ZR5A 4XM8A 1EAKA 3OHOA 3L0TA 1QJIA 4A7BA 1GKCA 2FV5A 2J83A 1C7KA 1G49A 3B2ZA 2E2DA 3NX7A 3F18A 1ZS0A 3RTTA 3DNGA 1HV5A 2L0RA 3KECA 2DDFA 4L19A 2JIHA 4Q1LA 1ASTA 4J4MA 4FVLA 5LABA 2X3CA 3RTSA 1K7GA 4L7AA 1JANA 3WV2A 1JIWP 1KUIA 2A8HA 1IAAA 1YCMA 4JQGA 1UEAA 4G9LA 830CA 2K9CA 1JAOA 2D1OA 4FXYP 4GR8A 2CKIA 2X7MA 2CLTA 4H3XA 1ZXVA 1KBCA 4HMAA 1FBLA 4L63A 5D1SA 1BM6A 4PKRA 1A85A 1Y0VA 4AUOA 3B92A 2Y6DA 1G12A 3LMCA 4L6TA 4I03A 4WZVA 3KHIA 2PJTA 2MZHA 1K7IA 4AXQA 3DTKA 3I7GA 3LIRA 2OVXA 1IAGA 2QPJA 1R54A 5D7WA 3HBVP 1KUKA 3F1AA 1IACA 2DW0A 4XCTA 2OY2A 1Q3AA 4QKZA 3LE9A 2ERPA 2OZRA 2OI0A 1OS2A 3EWJA 3EDGA 3N2VA 1YQYA 1ZTQA 3KEJA 4XM6A 1OO9A 3LQ0A 2MLSA 1OMJA 1IABA 1L6JA 1HFCA 4I35A 1OM7A 3Q2GA 2DW2A 4AYKA 2MZEA 1Y93A 2MZIA 3MA2A 3Q2HA 3KEKA 1ND1A 3HYGA 4FXQA 3EDIA 3K7LA 4H2EA 1XURA 1KUHA 5D1TA 5I4OA 1MMBA 4H82A 3AYKA 4EFSA 1ZVXA 1A86A 4JIJA 2X3BA 4H1QA 1QICA 1C3IA 2I47A 1J7NA 4PKUA 3AIGA 1R1IA 1AYKA 5BOYA 1XFVA 3B8ZA 1OZ9A 2OW9A 1MMPA 3BA0A 3F19A 3HY9A 1G9KA 2X3AA 4DF9A 5L79A 1JJ9A 5BPAA 1BZSA 1ZP5A 1S4BP 2OW2A 4IJOA 3LKAA 3WV3A 2USNA 1D7XA 1BKCE 1BQQM 1BIWA 2AYKA 1MMRA 1JKYA 3LK8A 3ELMA 1CGFA 1QIBA 1MMQA 4GQLA 5I0LA 2O36A 4DD8A 2OW1A 3USNA 1FLSA 2AIGP 2JT5A 4WKIA 2HU6A 1BUDA 1PWVA 5D2BA 2RJQA 1WNIA 3TS4A 1Z3JA 1CAQA 3EDHA 456CA 1PWWA 3VI1A 5I2ZA 3DTEA 3E8RA 1CK7A 1AKLA 5I12A 1H71P 1XAXA 2XS4A 1XM5A 3G5CA 4A3WA 1D5JA 5I3MA 1BSWA 1D8MA 5B5OA 3AYUA 3O64A 1JAPA 1GE5A 1SATA 1GE7A 3DWBA 1UTZA 1IADA 3HY7A 3ZUKA 4JA1A 1ZXCA 1CQRA 3HDBA 4H30A 4PKWA 2OW0A 3LIKA 1DMTA 1XFUA 5H8XA 1B8YA 1Y8JA 3N2UA 3U1RA 3V96B 5D3CA 4PKTA 3LUMA 1BKCA 3LJGA 4WKEA 2OVZA 3LJTA 3LUNA 2RJPA 3DPFA 1JAQA 1I73A 4GR0A 3P1VA 3F15A 3G42A 4JP4A 4ILWD 2OY4A 4JPAA 1RMZA 1PWPA 3EHXA 1GKDA 2ERQA 1UTTA 3DTIA 3LGPA 1HTDA 1QJJA 1R1HA 4ON1A 1UMSA 3UVCA 1XFXA 2V4BA 1QUAA 2FV9A 4WF6A 3L0VA 1G4KA 1B3DA 3LQBA 1EB6A 3KWVC 5CXAA 3DSLA 3HBUP 2W15A 2YB9A 2MLRA 3EHYA 1GO7P 4HX3A 4H84A 5BOTA 1KUFA 3ZXHA 4PKVA 1JIZA 1SRPA 3P24A 3O2XA 1HFSA 3KRYA 1BQOA 2W14A 4IUWA 1GE6A 1XUCA 4WK7A 5B5PA 5I43A 3DL1A 4PKSA 1EUBA 4GR3A 1SU3A 2JNPA 1HY7A 1HOVA 1KUGA 2SRTA 1IAEA 1XFYA 2WO9A 3EDZA 5L7FA 1SLNA 1RM8A 2JSDA 2XS3A 2YIGA 1XUDA 3WV1A 1MNCA 1XFWA 1YOUA 1OM6A 1XFZA 1TVIA 2OXWA 3TSKA 4G0DA 1GO8P 1D8FA 4AIGA 3F17A 3I7IA 3OHLA 1KAPP 5CUHA 1QIAA 1I1IP 4DV8A 4GUYA 4GWNA 1JK3A 1CGLA 2WO8A 1BKCI 2YUFA 1SLMA 3F16A 2O3EA 4H76A 1SMPA 4XM7A 4DPEA 3ZVSA 3KMCA 2OXUA 3VTGA 4H49A 3LEAA 3K7NA 1I76A 3CKIA 2W12A 2Y6CA 4R3VA 2W13A 1CGEA 4XBHA 3TVCA 2WOAA 3DPEA 2DDYA 1AF0A 1O0QA 1PWUA 4CTHA 1BUVM 2N8RA 1K7QA 1CIZA 4IN9A 1ROSA 2W0DA 5CZMA 5D1UA 2EROA 1GXDA 1USNA
chains in the Genus database with same CATH topology
3GBOA 3KMEA 1YP1A 4GWMA 4FU4A 4GF1A 2J0TA 3SHIA 5JMYA 1O0TA 1OS9A 2KRJA 2OXZA 3LILA 2DW1A 2E3XA 1DTHA 1FM1A 2JT6A 1R55A 3HB2P 2D1NA 1G05A 1ATLA 2K2GA 1PWQA 1UMTA 2POJA 1OM8A 2Z2DA 1CXVA 1C8TA 2TCLA 3HDAP 3LJZA 3TT4A 1R1JA 1JH1A 4PKQA 966CA 4ZR5A 4XM8A 1EAKA 3OHOA 3L0TA 1QJIA 4A7BA 1GKCA 2FV5A 2J83A 1C7KA 1G49A 3B2ZA 2E2DA 3NX7A 3F18A 1ZS0A 3RTTA 3DNGA 1HV5A 2L0RA 3KECA 2DDFA 4L19A 2JIHA 4Q1LA 1ASTA 4J4MA 4FVLA 5LABA 2X3CA 3RTSA 1K7GA 4L7AA 1JANA 3WV2A 1JIWP 1KUIA 2A8HA 1IAAA 1YCMA 4JQGA 1UEAA 4G9LA 830CA 2K9CA 1JAOA 2D1OA 4FXYP 4GR8A 2CKIA 2X7MA 2CLTA 4H3XA 1ZXVA 1KBCA 4HMAA 1FBLA 4L63A 5D1SA 1BM6A 4PKRA 1A85A 1Y0VA 4AUOA 3B92A 2Y6DA 1G12A 3LMCA 4L6TA 4I03A 4WZVA 3KHIA 2PJTA 2MZHA 1K7IA 4AXQA 3DTKA 3I7GA 3LIRA 2OVXA 1IAGA 2QPJA 1R54A 5D7WA 3HBVP 1KUKA 3F1AA 1IACA 2DW0A 4XCTA 2OY2A 1Q3AA 4QKZA 3LE9A 2ERPA 2OZRA 2OI0A 1OS2A 3EWJA 3EDGA 3N2VA 1YQYA 1ZTQA 3KEJA 4XM6A 1OO9A 3LQ0A 2MLSA 1OMJA 1IABA 1L6JA 1HFCA 4I35A 1OM7A 3Q2GA 2DW2A 4AYKA 2MZEA 1Y93A 2MZIA 3MA2A 3Q2HA 3KEKA 1ND1A 3HYGA 4FXQA 3EDIA 3K7LA 4H2EA 1XURA 1KUHA 5D1TA 5I4OA 1MMBA 4H82A 3AYKA 4EFSA 1ZVXA 1A86A 4JIJA 2X3BA 4H1QA 1QICA 1C3IA 2I47A 1J7NA 4PKUA 3AIGA 1R1IA 1AYKA 5BOYA 1XFVA 3B8ZA 2OW9A 1MMPA 3BA0A 3F19A 3HY9A 1G9KA 2X3AA 4DF9A 5L79A 1JJ9A 5BPAA 1BZSA 1ZP5A 1S4BP 2OW2A 4IJOA 3LKAA 3WV3A 2USNA 1D7XA 1BKCE 1BQQM 1BIWA 2AYKA 1MMRA 1JKYA 3LK8A 3ELMA 1CGFA 1QIBA 1MMQA 4GQLA 5I0LA 2O36A 4DD8A 2OW1A 3USNA 1FLSA 2AIGP 2JT5A 4WKIA 2HU6A 1BUDA 1PWVA 5D2BA 2RJQA 1WNIA 3TS4A 1Z3JA 1CAQA 3EDHA 456CA 1PWWA 3VI1A 5I2ZA 3DTEA 3E8RA 1CK7A 1AKLA 5I12A 1H71P 2XS4A 3G5CA 4A3WA 1D5JA 5I3MA 1BSWA 1D8MA 5B5OA 3AYUA 3O64A 1JAPA 1GE5A 1SATA 1GE7A 3DWBA 1UTZA 1IADA 3HY7A 3ZUKA 4JA1A 1ZXCA 1CQRA 3HDBA 4H30A 4PKWA 2OW0A 3LIKA 1DMTA 1XFUA 5H8XA 1B8YA 1Y8JA 3N2UA 3U1RA 3V96B 5D3CA 4PKTA 3LUMA 1BKCA 3LJGA 4WKEA 2OVZA 3LJTA 3LUNA 2RJPA 3DPFA 1JAQA 1I73A 4GR0A 3P1VA 3F15A 3G42A 4JP4A 4ILWD 2OY4A 4JPAA 1RMZA 1PWPA 3EHXA 1GKDA 2ERQA 1UTTA 3DTIA 3LGPA 1HTDA 1QJJA 1R1HA 4ON1A 1UMSA 3UVCA 1XFXA 2V4BA 1QUAA 2FV9A 4WF6A 3L0VA 1G4KA 1B3DA 3LQBA 1EB6A 3KWVC 5CXAA 3DSLA 3HBUP 2W15A 2YB9A 2MLRA 3EHYA 1GO7P 4HX3A 4H84A 5BOTA 1KUFA 3ZXHA 4PKVA 1JIZA 1SRPA 3P24A 3O2XA 1HFSA 3KRYA 1BQOA 2W14A 4IUWA 1GE6A 1XUCA 4WK7A 5B5PA 5I43A 3DL1A 4PKSA 1EUBA 4GR3A 1SU3A 2JNPA 1HY7A 1HOVA 1KUGA 2SRTA 1IAEA 1XFYA 2WO9A 3EDZA 5L7FA 1SLNA 1RM8A 2JSDA 2XS3A 2YIGA 1XUDA 3WV1A 1MNCA 1XFWA 1YOUA 1OM6A 1XFZA 2OXWA 3TSKA 4G0DA 1GO8P 1D8FA 4AIGA 3F17A 3I7IA 3OHLA 1KAPP 5CUHA 1QIAA 1I1IP 4DV8A 4GUYA 4GWNA 1JK3A 1CGLA 2WO8A 1BKCI 2YUFA 1SLMA 3F16A 2O3EA 4H76A 1SMPA 4XM7A 4DPEA 3ZVSA 3KMCA 2OXUA 3VTGA 4H49A 3LEAA 3K7NA 1I76A 3CKIA 2W12A 2Y6CA 4R3VA 2W13A 1CGEA 4XBHA 3TVCA 2WOAA 3DPEA 2DDYA 1AF0A 1O0QA 1PWUA 4CTHA 1BUVM 2N8RA 1K7QA 1CIZA 4IN9A 1ROSA 2W0DA 5CZMA 5D1UA 2EROA 1GXDA 1USNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GBO A;  3KME A;  1YP1 A;  4GWM A;  4FU4 A;  4GF1 A;  2J0T A;  3SHI A;  5JMY A;  1O0T A;  1OS9 A;  2KRJ A;  2OXZ A;  3LIL A;  2DW1 A;  2E3X A;  1DTH A;  1FM1 A;  2JT6 A;  1R55 A;  3HB2 P;  2D1N A;  1G05 A;  1ATL A;  2K2G A;  1PWQ A;  1UMT A;  2POJ A;  1OM8 A;  2Z2D A;  1CXV A;  1C8T A;  2TCL A;  3HDA P;  3LJZ A;  3TT4 A;  1R1J A;  1JH1 A;  4PKQ A;  966C A;  4ZR5 A;  4XM8 A;  1EAK A;  3OHO A;  3L0T A;  1QJI A;  4A7B A;  1GKC A;  2FV5 A;  2J83 A;  1C7K A;  1G49 A;  3B2Z A;  2E2D A;  3NX7 A;  3F18 A;  1ZS0 A;  3RTT A;  3DNG A;  1HV5 A;  2L0R A;  3KEC A;  2DDF A;  4L19 A;  2JIH A;  4Q1L A;  1AST A;  4J4M A;  4FVL A;  5LAB A;  2X3C A;  3RTS A;  1K7G A;  1JAN A;  3WV2 A;  1JIW P;  1KUI A;  2A8H A;  1IAA A;  1YCM A;  4JQG A;  1UEA A;  4G9L A;  830C A;  2K9C A;  1JAO A;  2D1O A;  4FXY P;  4GR8 A;  2CKI A;  2X7M A;  2CLT A;  4H3X A;  1ZXV A;  1KBC A;  4HMA A;  1FBL A;  4L63 A;  5D1S A;  1BM6 A;  4PKR A;  1A85 A;  1Y0V A;  4AUO A;  3B92 A;  2Y6D A;  1G12 A;  3LMC A;  4L6T A;  4I03 A;  4WZV A;  3KHI A;  2PJT A;  2MZH A;  1K7I A;  4AXQ A;  3I7G A;  3LIR A;  2OVX A;  1IAG A;  2QPJ A;  1R54 A;  5D7W A;  3HBV P;  1KUK A;  3F1A A;  1IAC A;  2DW0 A;  4XCT A;  2OY2 A;  1Q3A A;  4QKZ A;  3LE9 A;  2ERP A;  2OZR A;  2OI0 A;  1OS2 A;  3EWJ A;  3EDG A;  3N2V A;  1YQY A;  1ZTQ A;  3KEJ A;  4XM6 A;  1OO9 A;  3LQ0 A;  2MLS A;  1OMJ A;  1IAB A;  1L6J A;  1HFC A;  4I35 A;  1OM7 A;  3Q2G A;  2DW2 A;  4AYK A;  2MZE A;  1Y93 A;  2MZI A;  3MA2 A;  3Q2H A;  3KEK A;  1ND1 A;  3HYG A;  4FXQ A;  3EDI A;  3K7L A;  4H2E A;  1XUR A;  1KUH A;  5D1T A;  5I4O A;  1MMB A;  4H82 A;  3AYK A;  4EFS A;  1ZVX A;  1A86 A;  4JIJ A;  2X3B A;  4H1Q A;  1QIC A;  1C3I A;  2I47 A;  1J7N A;  4PKU A;  3AIG A;  1R1I A;  1AYK A;  5BOY A;  1XFV A;  3B8Z A;  2OW9 A;  1MMP A;  3BA0 A;  3F19 A;  3HY9 A;  1G9K A;  2X3A A;  4DF9 A;  5L79 A;  1JJ9 A;  5BPA A;  1BZS A;  1ZP5 A;  1S4B P;  2OW2 A;  4IJO A;  3LKA A;  3WV3 A;  2USN A;  1D7X A;  1BKC E;  1BQQ M;  1BIW A;  2AYK A;  1MMR A;  1JKY A;  3LK8 A;  3ELM A;  1CGF A;  1QIB A;  1MMQ A;  4GQL A;  5I0L A;  2O36 A;  4DD8 A;  2OW1 A;  3USN A;  1FLS A;  2AIG P;  2JT5 A;  4WKI A;  2HU6 A;  1BUD A;  1PWV A;  5D2B A;  2RJQ A;  1WNI A;  3TS4 A;  1Z3J A;  1CAQ A;  3EDH A;  456C A;  1PWW A;  3VI1 A;  5I2Z A;  3E8R A;  1CK7 A;  1AKL A;  5I12 A;  1H71 P;  2XS4 A;  3G5C A;  4A3W A;  1D5J A;  5I3M A;  1BSW A;  1D8M A;  5B5O A;  3AYU A;  3O64 A;  1JAP A;  1GE5 A;  1SAT A;  1GE7 A;  3DWB A;  1UTZ A;  1IAD A;  3HY7 A;  3ZUK A;  4JA1 A;  1ZXC A;  1CQR A;  3HDB A;  4H30 A;  4PKW A;  2OW0 A;  3LIK A;  1DMT A;  1XFU A;  5H8X A;  1B8Y A;  1Y8J A;  3N2U A;  3U1R A;  3V96 B;  5D3C A;  4PKT A;  3LUM A;  1BKC A;  3LJG A;  4WKE A;  2OVZ A;  3LJT A;  3LUN A;  2RJP A;  3DPF A;  1JAQ A;  1I73 A;  4GR0 A;  3P1V A;  3F15 A;  3G42 A;  4JP4 A;  4ILW D;  2OY4 A;  4JPA A;  1RMZ A;  1PWP A;  3EHX A;  1GKD A;  2ERQ A;  1UTT A;  3LGP A;  1HTD A;  1QJJ A;  1R1H A;  4ON1 A;  1UMS A;  3UVC A;  1XFX A;  2V4B A;  1QUA A;  2FV9 A;  4WF6 A;  3L0V A;  1G4K A;  1B3D A;  3LQB A;  1EB6 A;  3KWV C;  5CXA A;  3DSL A;  3HBU P;  2W15 A;  2YB9 A;  2MLR A;  3EHY A;  1GO7 P;  4HX3 A;  4H84 A;  5BOT A;  1KUF A;  3ZXH A;  4PKV A;  1JIZ A;  1SRP A;  3P24 A;  3O2X A;  1HFS A;  3KRY A;  1BQO A;  2W14 A;  4IUW A;  1GE6 A;  1XUC A;  4WK7 A;  5B5P A;  5I43 A;  3DL1 A;  4PKS A;  1EUB A;  4GR3 A;  1SU3 A;  2JNP A;  1HY7 A;  1HOV A;  1KUG A;  2SRT A;  1IAE A;  1XFY A;  2WO9 A;  3EDZ A;  5L7F A;  1SLN A;  1RM8 A;  2JSD A;  2XS3 A;  2YIG A;  1XUD A;  3WV1 A;  1MNC A;  1XFW A;  1YOU A;  1OM6 A;  1XFZ A;  2OXW A;  3TSK A;  4G0D A;  1GO8 P;  1D8F A;  4AIG A;  3F17 A;  3I7I A;  3OHL A;  1KAP P;  5CUH A;  1QIA A;  1I1I P;  4DV8 A;  4GUY A;  4GWN A;  1JK3 A;  1CGL A;  2WO8 A;  1BKC I;  1SLM A;  3F16 A;  2O3E A;  4H76 A;  1SMP A;  4XM7 A;  4DPE A;  3ZVS A;  3KMC A;  2OXU A;  3VTG A;  4H49 A;  3LEA A;  3K7N A;  1I76 A;  3CKI A;  2W12 A;  2Y6C A;  4R3V A;  2W13 A;  1CGE A;  4XBH A;  3TVC A;  2WOA A;  3DPE A;  2DDY A;  1AF0 A;  1O0Q A;  1PWU A;  4CTH A;  1BUV M;  2N8R A;  1K7Q A;  1CIZ A;  4IN9 A;  1ROS A;  2W0D A;  5CZM A;  5D1U A;  2ERO A;  1GXD A;  1USN A; 
#chains in the Genus database with same CATH topology
 3GBO A;  3KME A;  1YP1 A;  4GWM A;  4FU4 A;  4GF1 A;  2J0T A;  3SHI A;  5JMY A;  1O0T A;  1OS9 A;  2KRJ A;  2OXZ A;  3LIL A;  2DW1 A;  2E3X A;  1DTH A;  1FM1 A;  2JT6 A;  1R55 A;  3HB2 P;  2D1N A;  1G05 A;  1ATL A;  2K2G A;  1PWQ A;  1UMT A;  2POJ A;  1OM8 A;  2Z2D A;  1CXV A;  1C8T A;  2TCL A;  3HDA P;  3LJZ A;  3TT4 A;  1R1J A;  1JH1 A;  4PKQ A;  966C A;  4ZR5 A;  4XM8 A;  1EAK A;  3OHO A;  3L0T A;  1QJI A;  4A7B A;  1GKC A;  2FV5 A;  2J83 A;  1C7K A;  1G49 A;  3B2Z A;  2E2D A;  3NX7 A;  3F18 A;  1ZS0 A;  3RTT A;  3DNG A;  1HV5 A;  2L0R A;  3KEC A;  2DDF A;  4L19 A;  2JIH A;  4Q1L A;  1AST A;  4J4M A;  4FVL A;  5LAB A;  2X3C A;  3RTS A;  1K7G A;  4L7A A;  1JAN A;  3WV2 A;  1JIW P;  1KUI A;  2A8H A;  1IAA A;  1YCM A;  4JQG A;  1UEA A;  4G9L A;  830C A;  2K9C A;  1JAO A;  2D1O A;  4FXY P;  4GR8 A;  2CKI A;  2X7M A;  2CLT A;  4H3X A;  1ZXV A;  1KBC A;  4HMA A;  1FBL A;  4L63 A;  5D1S A;  1BM6 A;  4PKR A;  1A85 A;  1Y0V A;  4AUO A;  3B92 A;  2Y6D A;  1G12 A;  3LMC A;  4L6T A;  4I03 A;  4WZV A;  3KHI A;  2PJT A;  2MZH A;  1K7I A;  4AXQ A;  3DTK A;  3I7G A;  3LIR A;  2OVX A;  1IAG A;  2QPJ A;  1R54 A;  5D7W A;  3HBV P;  1KUK A;  3F1A A;  1IAC A;  2DW0 A;  4XCT A;  2OY2 A;  1Q3A A;  4QKZ A;  3LE9 A;  2ERP A;  2OZR A;  2OI0 A;  1OS2 A;  3EWJ A;  3EDG A;  3N2V A;  1YQY A;  1ZTQ A;  3KEJ A;  4XM6 A;  1OO9 A;  3LQ0 A;  2MLS A;  1OMJ A;  1IAB A;  1L6J A;  1HFC A;  4I35 A;  1OM7 A;  3Q2G A;  2DW2 A;  4AYK A;  2MZE A;  1Y93 A;  2MZI A;  3MA2 A;  3Q2H A;  3KEK A;  1ND1 A;  3HYG A;  4FXQ A;  3EDI A;  3K7L A;  4H2E A;  1XUR A;  1KUH A;  5D1T A;  5I4O A;  1MMB A;  4H82 A;  3AYK A;  4EFS A;  1ZVX A;  1A86 A;  4JIJ A;  2X3B A;  4H1Q A;  1QIC A;  1C3I A;  2I47 A;  1J7N A;  4PKU A;  3AIG A;  1R1I A;  1AYK A;  5BOY A;  1XFV A;  3B8Z A;  1OZ9 A;  2OW9 A;  1MMP A;  3BA0 A;  3F19 A;  3HY9 A;  1G9K A;  2X3A A;  4DF9 A;  5L79 A;  1JJ9 A;  5BPA A;  1BZS A;  1ZP5 A;  1S4B P;  2OW2 A;  4IJO A;  3LKA A;  3WV3 A;  2USN A;  1D7X A;  1BKC E;  1BQQ M;  1BIW A;  2AYK A;  1MMR A;  1JKY A;  3LK8 A;  3ELM A;  1CGF A;  1QIB A;  1MMQ A;  4GQL A;  5I0L A;  2O36 A;  4DD8 A;  2OW1 A;  3USN A;  1FLS A;  2AIG P;  2JT5 A;  4WKI A;  2HU6 A;  1BUD A;  1PWV A;  5D2B A;  2RJQ A;  1WNI A;  3TS4 A;  1Z3J A;  1CAQ A;  3EDH A;  456C A;  1PWW A;  3VI1 A;  5I2Z A;  3DTE A;  3E8R A;  1CK7 A;  1AKL A;  5I12 A;  1H71 P;  1XAX A;  2XS4 A;  1XM5 A;  3G5C A;  4A3W A;  1D5J A;  5I3M A;  1BSW A;  1D8M A;  5B5O A;  3AYU A;  3O64 A;  1JAP A;  1GE5 A;  1SAT A;  1GE7 A;  3DWB A;  1UTZ A;  1IAD A;  3HY7 A;  3ZUK A;  4JA1 A;  1ZXC A;  1CQR A;  3HDB A;  4H30 A;  4PKW A;  2OW0 A;  3LIK A;  1DMT A;  1XFU A;  5H8X A;  1B8Y A;  1Y8J A;  3N2U A;  3U1R A;  3V96 B;  5D3C A;  4PKT A;  3LUM A;  1BKC A;  3LJG A;  4WKE A;  2OVZ A;  3LJT A;  3LUN A;  2RJP A;  3DPF A;  1JAQ A;  1I73 A;  4GR0 A;  3P1V A;  3F15 A;  3G42 A;  4JP4 A;  4ILW D;  2OY4 A;  4JPA A;  1RMZ A;  1PWP A;  3EHX A;  1GKD A;  2ERQ A;  1UTT A;  3DTI A;  3LGP A;  1HTD A;  1QJJ A;  1R1H A;  4ON1 A;  1UMS A;  3UVC A;  1XFX A;  2V4B A;  1QUA A;  2FV9 A;  4WF6 A;  3L0V A;  1G4K A;  1B3D A;  3LQB A;  1EB6 A;  3KWV C;  5CXA A;  3DSL A;  3HBU P;  2W15 A;  2YB9 A;  2MLR A;  3EHY A;  1GO7 P;  4HX3 A;  4H84 A;  5BOT A;  1KUF A;  3ZXH A;  4PKV A;  1JIZ A;  1SRP A;  3P24 A;  3O2X A;  1HFS A;  3KRY A;  1BQO A;  2W14 A;  4IUW A;  1GE6 A;  1XUC A;  4WK7 A;  5B5P A;  5I43 A;  3DL1 A;  4PKS A;  1EUB A;  4GR3 A;  1SU3 A;  2JNP A;  1HY7 A;  1HOV A;  1KUG A;  2SRT A;  1IAE A;  1XFY A;  2WO9 A;  3EDZ A;  5L7F A;  1SLN A;  1RM8 A;  2JSD A;  2XS3 A;  2YIG A;  1XUD A;  3WV1 A;  1MNC A;  1XFW A;  1YOU A;  1OM6 A;  1XFZ A;  1TVI A;  2OXW A;  3TSK A;  4G0D A;  1GO8 P;  1D8F A;  4AIG A;  3F17 A;  3I7I A;  3OHL A;  1KAP P;  5CUH A;  1QIA A;  1I1I P;  4DV8 A;  4GUY A;  4GWN A;  1JK3 A;  1CGL A;  2WO8 A;  1BKC I;  2YUF A;  1SLM A;  3F16 A;  2O3E A;  4H76 A;  1SMP A;  4XM7 A;  4DPE A;  3ZVS A;  3KMC A;  2OXU A;  3VTG A;  4H49 A;  3LEA A;  3K7N A;  1I76 A;  3CKI A;  2W12 A;  2Y6C A;  4R3V A;  2W13 A;  1CGE A;  4XBH A;  3TVC A;  2WOA A;  3DPE A;  2DDY A;  1AF0 A;  1O0Q A;  1PWU A;  4CTH A;  1BUV M;  2N8R A;  1K7Q A;  1CIZ A;  4IN9 A;  1ROS A;  2W0D A;  5CZM A;  5D1U A;  2ERO A;  1GXD A;  1USN A; 
#chains in the Genus database with same CATH homology
 3GBO A;  3KME A;  1YP1 A;  4GWM A;  4FU4 A;  4GF1 A;  2J0T A;  3SHI A;  5JMY A;  1O0T A;  1OS9 A;  2KRJ A;  2OXZ A;  3LIL A;  2DW1 A;  2E3X A;  1DTH A;  1FM1 A;  2JT6 A;  1R55 A;  3HB2 P;  2D1N A;  1G05 A;  1ATL A;  2K2G A;  1PWQ A;  1UMT A;  2POJ A;  1OM8 A;  2Z2D A;  1CXV A;  1C8T A;  2TCL A;  3HDA P;  3LJZ A;  3TT4 A;  1R1J A;  1JH1 A;  4PKQ A;  966C A;  4ZR5 A;  4XM8 A;  1EAK A;  3OHO A;  3L0T A;  1QJI A;  4A7B A;  1GKC A;  2FV5 A;  2J83 A;  1C7K A;  1G49 A;  3B2Z A;  2E2D A;  3NX7 A;  3F18 A;  1ZS0 A;  3RTT A;  3DNG A;  1HV5 A;  2L0R A;  3KEC A;  2DDF A;  4L19 A;  2JIH A;  4Q1L A;  1AST A;  4J4M A;  4FVL A;  5LAB A;  2X3C A;  3RTS A;  1K7G A;  4L7A A;  1JAN A;  3WV2 A;  1JIW P;  1KUI A;  2A8H A;  1IAA A;  1YCM A;  4JQG A;  1UEA A;  4G9L A;  830C A;  2K9C A;  1JAO A;  2D1O A;  4FXY P;  4GR8 A;  2CKI A;  2X7M A;  2CLT A;  4H3X A;  1ZXV A;  1KBC A;  4HMA A;  1FBL A;  4L63 A;  5D1S A;  1BM6 A;  4PKR A;  1A85 A;  1Y0V A;  4AUO A;  3B92 A;  2Y6D A;  1G12 A;  3LMC A;  4L6T A;  4I03 A;  4WZV A;  3KHI A;  2PJT A;  2MZH A;  1K7I A;  4AXQ A;  3DTK A;  3I7G A;  3LIR A;  2OVX A;  1IAG A;  2QPJ A;  1R54 A;  5D7W A;  3HBV P;  1KUK A;  3F1A A;  1IAC A;  2DW0 A;  4XCT A;  2OY2 A;  1Q3A A;  4QKZ A;  3LE9 A;  2ERP A;  2OZR A;  2OI0 A;  1OS2 A;  3EWJ A;  3EDG A;  3N2V A;  1YQY A;  1ZTQ A;  3KEJ A;  4XM6 A;  1OO9 A;  3LQ0 A;  2MLS A;  1OMJ A;  1IAB A;  1L6J A;  1HFC A;  4I35 A;  1OM7 A;  3Q2G A;  2DW2 A;  4AYK A;  2MZE A;  1Y93 A;  2MZI A;  3MA2 A;  3Q2H A;  3KEK A;  1ND1 A;  3HYG A;  4FXQ A;  3EDI A;  3K7L A;  4H2E A;  1XUR A;  1KUH A;  5D1T A;  5I4O A;  1MMB A;  4H82 A;  3AYK A;  4EFS A;  1ZVX A;  1A86 A;  4JIJ A;  2X3B A;  4H1Q A;  1QIC A;  1C3I A;  2I47 A;  1J7N A;  4PKU A;  3AIG A;  1R1I A;  1AYK A;  5BOY A;  1XFV A;  3B8Z A;  2OW9 A;  1MMP A;  3BA0 A;  3F19 A;  3HY9 A;  1G9K A;  2X3A A;  4DF9 A;  5L79 A;  1JJ9 A;  5BPA A;  1BZS A;  1ZP5 A;  1S4B P;  2OW2 A;  4IJO A;  3LKA A;  3WV3 A;  2USN A;  1D7X A;  1BKC E;  1BQQ M;  1BIW A;  2AYK A;  1MMR A;  1JKY A;  3LK8 A;  3ELM A;  1CGF A;  1QIB A;  1MMQ A;  4GQL A;  5I0L A;  2O36 A;  4DD8 A;  2OW1 A;  3USN A;  1FLS A;  2AIG P;  2JT5 A;  4WKI A;  2HU6 A;  1BUD A;  1PWV A;  5D2B A;  2RJQ A;  1WNI A;  3TS4 A;  1Z3J A;  1CAQ A;  3EDH A;  456C A;  1PWW A;  3VI1 A;  5I2Z A;  3DTE A;  3E8R A;  1CK7 A;  1AKL A;  5I12 A;  1H71 P;  2XS4 A;  3G5C A;  4A3W A;  1D5J A;  5I3M A;  1BSW A;  1D8M A;  5B5O A;  3AYU A;  3O64 A;  1JAP A;  1GE5 A;  1SAT A;  1GE7 A;  3DWB A;  1UTZ A;  1IAD A;  3HY7 A;  3ZUK A;  4JA1 A;  1ZXC A;  1CQR A;  3HDB A;  4H30 A;  4PKW A;  2OW0 A;  3LIK A;  1DMT A;  1XFU A;  5H8X A;  1B8Y A;  1Y8J A;  3N2U A;  3U1R A;  3V96 B;  5D3C A;  4PKT A;  3LUM A;  1BKC A;  3LJG A;  4WKE A;  2OVZ A;  3LJT A;  3LUN A;  2RJP A;  3DPF A;  1JAQ A;  1I73 A;  4GR0 A;  3P1V A;  3F15 A;  3G42 A;  4JP4 A;  4ILW D;  2OY4 A;  4JPA A;  1RMZ A;  1PWP A;  3EHX A;  1GKD A;  2ERQ A;  1UTT A;  3DTI A;  3LGP A;  1HTD A;  1QJJ A;  1R1H A;  4ON1 A;  1UMS A;  3UVC A;  1XFX A;  2V4B A;  1QUA A;  2FV9 A;  4WF6 A;  3L0V A;  1G4K A;  1B3D A;  3LQB A;  1EB6 A;  3KWV C;  5CXA A;  3DSL A;  3HBU P;  2W15 A;  2YB9 A;  2MLR A;  3EHY A;  1GO7 P;  4HX3 A;  4H84 A;  5BOT A;  1KUF A;  3ZXH A;  4PKV A;  1JIZ A;  1SRP A;  3P24 A;  3O2X A;  1HFS A;  3KRY A;  1BQO A;  2W14 A;  4IUW A;  1GE6 A;  1XUC A;  4WK7 A;  5B5P A;  5I43 A;  3DL1 A;  4PKS A;  1EUB A;  4GR3 A;  1SU3 A;  2JNP A;  1HY7 A;  1HOV A;  1KUG A;  2SRT A;  1IAE A;  1XFY A;  2WO9 A;  3EDZ A;  5L7F A;  1SLN A;  1RM8 A;  2JSD A;  2XS3 A;  2YIG A;  1XUD A;  3WV1 A;  1MNC A;  1XFW A;  1YOU A;  1OM6 A;  1XFZ A;  2OXW A;  3TSK A;  4G0D A;  1GO8 P;  1D8F A;  4AIG A;  3F17 A;  3I7I A;  3OHL A;  1KAP P;  5CUH A;  1QIA A;  1I1I P;  4DV8 A;  4GUY A;  4GWN A;  1JK3 A;  1CGL A;  2WO8 A;  1BKC I;  2YUF A;  1SLM A;  3F16 A;  2O3E A;  4H76 A;  1SMP A;  4XM7 A;  4DPE A;  3ZVS A;  3KMC A;  2OXU A;  3VTG A;  4H49 A;  3LEA A;  3K7N A;  1I76 A;  3CKI A;  2W12 A;  2Y6C A;  4R3V A;  2W13 A;  1CGE A;  4XBH A;  3TVC A;  2WOA A;  3DPE A;  2DDY A;  1AF0 A;  1O0Q A;  1PWU A;  4CTH A;  1BUV M;  2N8R A;  1K7Q A;  1CIZ A;  4IN9 A;  1ROS A;  2W0D A;  5CZM A;  5D1U A;  2ERO A;  1GXD A;  1USN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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