1IMXA

1.8 angstrom crystal structure of igf-1
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
62
structure length
56
Chain Sequence
ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSTGIVDECCFRSCDLRRLEMYCAPL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone/growth factor
molecule keywords Insulin-like Growth Factor 1A
publication title Crystal structure of human insulin-like growth factor-1: detergent binding inhibits binding protein interactions.
pubmed doi rcsb
source organism Homo sapiens
total genus 16
structure length 56
sequence length 62
ec nomenclature
pdb deposition date 2001-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1imxA00
1IGLA 3GF1A 1SJUA 5L3NA 1H59A 5L3LA 6INSE 2L29B 1H02B 1TGRA 2DSPI 3KR3D 2LWZA 4XSSB 2GF1A 1IMXA 2DSQC 1B9GA 2DSRI 2JZQA 1BQTA 1GZRB 3LRIA 1GZYB 1EFEA 1WQJI 2KQPA 1ZEIA 1GZZB 1PMXA 5L3MA 2KJIA
chains in the Genus database with same CATH superfamily
1IGLA 2L14B 3GF1A 1SJUA 5L3NA 1H59A 5L3LA 6INSE 2L29B 1H02B 1TGRA 2DSPI 3KR3D 2LWZA 4XSSB 3F2BA 2GF1A 1IMXA 2DSQC 3F2DA 3F2CA 1B9GA 2DSRI 2JZQA 1BQTA 1GZRB 3LRIA 1GZYB 1EFEA 1WQJI 2KQPA 1ZEIA 1GZZB 1PMXA 5L3MA 2KJIA
chains in the Genus database with same CATH topology
1IGLA 3GF1A 1SJUA 5L3NA 1H59A 5L3LA 6INSE 2L29B 1H02B 1TGRA 2DSPI 3KR3D 2LWZA 4XSSB 2GF1A 1IMXA 2DSQC 1B9GA 2DSRI 2JZQA 1BQTA 1GZRB 3LRIA 1GZYB 1EFEA 1WQJI 2KQPA 1ZEIA 1GZZB 1PMXA 5L3MA 2KJIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IGL A;  3GF1 A;  1SJU A;  5L3N A;  1H59 A;  5L3L A;  6INS E;  2L29 B;  1H02 B;  1TGR A;  2DSP I;  3KR3 D;  2LWZ A;  4XSS B;  2GF1 A;  1IMX A;  2DSQ C;  1B9G A;  2DSR I;  2JZQ A;  1BQT A;  1GZR B;  3LRI A;  1GZY B;  1EFE A;  1WQJ I;  2KQP A;  1ZEI A;  1GZZ B;  1PMX A;  5L3M A;  2KJI A; 
#chains in the Genus database with same CATH topology
 1IGL A;  2L14 B;  3GF1 A;  1SJU A;  5L3N A;  1H59 A;  5L3L A;  6INS E;  2L29 B;  1H02 B;  1TGR A;  2DSP I;  3KR3 D;  2LWZ A;  4XSS B;  3F2B A;  2GF1 A;  1IMX A;  2DSQ C;  3F2D A;  3F2C A;  1B9G A;  2DSR I;  2JZQ A;  1BQT A;  1GZR B;  3LRI A;  1GZY B;  1EFE A;  1WQJ I;  2KQP A;  1ZEI A;  1GZZ B;  1PMX A;  5L3M A;  2KJI A; 
#chains in the Genus database with same CATH homology
 1IGL A;  3GF1 A;  1SJU A;  5L3N A;  1H59 A;  5L3L A;  6INS E;  2L29 B;  1H02 B;  1TGR A;  2DSP I;  3KR3 D;  2LWZ A;  4XSS B;  2GF1 A;  1IMX A;  2DSQ C;  1B9G A;  2DSR I;  2JZQ A;  1BQT A;  1GZR B;  3LRI A;  1GZY B;  1EFE A;  1WQJ I;  2KQP A;  1ZEI A;  1GZZ B;  1PMX A;  5L3M A;  2KJI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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