1IZ4A

Pyrococcus furiosus pcna mutant (met73leu/asp143ala): tetragonal form
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
246
structure length
241
Chain Sequence
PFEIVFEGAKEFAQLIDTASKLIDEAAFKVTEDGISMRAMDPSRVVLIDLNLPSSIFSKYEVVEPETIGVNLDHLKKILKRGKAKDTLILKKGEENFLEITIQGTATRTFRVPLIDVEEPELPFTAKVVVLGEVLKAAVKDASLVSDSIKFIARENEFIMKAEGETQEVEIKLTLEDEGLLDIEVQEETKSAYGVSYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLTFLLAPRV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA
pubmed doi rcsb
molecule keywords Proliferating cell nuclear antigen
molecule tags Dna binding protein
source organism Pyrococcus furiosus
total genus 59
structure length 241
sequence length 246
ec nomenclature
pdb deposition date 2002-09-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1iz4A00
2HIIB 3V62B 2AWAA 3HSLX 2Z0LA 4L60A 4RJFA 3GGRC 3AIXB 3G65B 3A1JC 1B8HA 1W60A 3P91A 2NTIC 1SXJF 5A6DA 2IO4A 1RXZA 3IFVA 4ZTDA 2HIIC 2IJXA 5JNED 5CFKA 1B77A 3AIZC 3U61F 2HIKB 4D2GA 3A2FB 3G65C 3U5ZF 3AIZA 3G65A 3TBLA 3FDSC 1IZ4A 1UD9A 1VYMA 1IZ5A 3FDSD 3GGRA 5AUJA 2ZVWA 3A1JA 2HIKC 2IX2B 1GE8A 3V61B 3GPNA 2NTIA 1U76A 2HIKA 1PLRA 2HIIA 4HK1A 1RXMA 5HACA 3AIXA 1AXCA 5IXAA 3K4XA 2IX2C 2IZOB 3LX2A 4TR6A 1UL1A 3GPMA 2IX2A 5H0TA 2ZVKA 1CZDA 2AVTA 5IY4A 4L6PA 5IWDA 3WGWA 5DA7A 1PLQA 3P83A 1ISQA 3P87A 2ZVVA 2IZOC 1U7BA 3U60F 4CS5A 3V60B 2ZVMA 5E0VA 5DAIA 3GGRB 1T6LA 3F1WA 3LX1A 3A1JB 1VYJA 1DMLA 2OD8A 3I2MX 2IO4B 5E0TA 5B7OA 4YHRA 3VKXA 1RWZA 1YYPA 5E0UA 2NTIB 2ZVLA 3HI8A
chains in the Genus database with same CATH superfamily
2HIIB 3V62B 2AWAA 3HSLX 2Z0LA 4L60A 4RJFA 3GGRC 3AIXB 3G65B 3A1JC 1B8HA 1W60A 3P91A 2NTIC 1SXJF 5A6DA 2IO4A 1RXZA 3IFVA 4ZTDA 2HIIC 2IJXA 5JNED 5CFKA 1B77A 3AIZC 3U61F 2HIKB 4D2GA 3A2FB 3G65C 3U5ZF 3AIZA 3G65A 3TBLA 3FDSC 1IZ4A 1UD9A 1VYMA 1IZ5A 3FDSD 3GGRA 5AUJA 2ZVWA 3A1JA 2HIKC 2IX2B 1GE8A 3V61B 3GPNA 2NTIA 1U76A 2HIKA 1PLRA 2HIIA 4HK1A 1RXMA 5HACA 3AIXA 1AXCA 5IXAA 3K4XA 2IX2C 2IZOB 3LX2A 4TR6A 1UL1A 3GPMA 2IX2A 5H0TA 2ZVKA 1CZDA 2AVTA 5IY4A 4L6PA 5IWDA 3WGWA 5DA7A 1PLQA 3P83A 1ISQA 3P87A 2ZVVA 2IZOC 1U7BA 3U60F 4CS5A 3V60B 2ZVMA 5E0VA 5DAIA 3GGRB 1T6LA 3F1WA 3LX1A 3A1JB 1VYJA 1DMLA 2OD8A 3I2MX 2IO4B 5E0TA 5B7OA 4YHRA 3VKXA 1RWZA 1YYPA 5E0UA 2NTIB 2ZVLA 3HI8A
chains in the Genus database with same CATH topology
2HIIB 3V62B 2AWAA 3HSLX 2Z0LA 4L60A 4RJFA 3GGRC 3AIXB 3G65B 3A1JC 1B8HA 1W60A 3P91A 2NTIC 1SXJF 5A6DA 2IO4A 1RXZA 3IFVA 4ZTDA 2HIIC 2IJXA 5JNED 5CFKA 1B77A 3AIZC 3U61F 2HIKB 4D2GA 3A2FB 3G65C 3U5ZF 3AIZA 3G65A 3TBLA 3FDSC 1IZ4A 1UD9A 1VYMA 1IZ5A 3FDSD 3GGRA 5AUJA 2ZVWA 3A1JA 2HIKC 2IX2B 1GE8A 3V61B 3GPNA 2NTIA 1U76A 2HIKA 1PLRA 2HIIA 4HK1A 1RXMA 5HACA 3AIXA 1AXCA 5IXAA 3K4XA 2IX2C 2IZOB 3LX2A 4TR6A 1UL1A 3GPMA 2IX2A 5H0TA 2ZVKA 1CZDA 2AVTA 5IY4A 4L6PA 5IWDA 3WGWA 5DA7A 1PLQA 3P83A 1ISQA 3P87A 2ZVVA 2IZOC 1U7BA 3U60F 4CS5A 3V60B 2ZVMA 5E0VA 5DAIA 3GGRB 1T6LA 3F1WA 3LX1A 3A1JB 1VYJA 1DMLA 2OD8A 3I2MX 2IO4B 5E0TA 5B7OA 4YHRA 3VKXA 1RWZA 1YYPA 5E0UA 2NTIB 2ZVLA 3HI8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HII B;  3V62 B;  2AWA A;  3HSL X;  2Z0L A;  4L60 A;  4RJF A;  3GGR C;  3AIX B;  3G65 B;  3A1J C;  1B8H A;  1W60 A;  3P91 A;  2NTI C;  1SXJ F;  5A6D A;  2IO4 A;  1RXZ A;  3IFV A;  4ZTD A;  2HII C;  2IJX A;  5JNE D;  5CFK A;  1B77 A;  3AIZ C;  3U61 F;  2HIK B;  4D2G A;  3A2F B;  3G65 C;  3U5Z F;  3AIZ A;  3G65 A;  3TBL A;  3FDS C;  1IZ4 A;  1UD9 A;  1VYM A;  1IZ5 A;  3FDS D;  3GGR A;  5AUJ A;  2ZVW A;  3A1J A;  2HIK C;  2IX2 B;  1GE8 A;  3V61 B;  3GPN A;  2NTI A;  1U76 A;  2HIK A;  1PLR A;  2HII A;  4HK1 A;  1RXM A;  5HAC A;  3AIX A;  1AXC A;  5IXA A;  3K4X A;  2IX2 C;  2IZO B;  3LX2 A;  4TR6 A;  1UL1 A;  3GPM A;  2IX2 A;  5H0T A;  2ZVK A;  1CZD A;  2AVT A;  5IY4 A;  4L6P A;  5IWD A;  3WGW A;  5DA7 A;  1PLQ A;  3P83 A;  1ISQ A;  3P87 A;  2ZVV A;  2IZO C;  1U7B A;  3U60 F;  4CS5 A;  3V60 B;  2ZVM A;  5E0V A;  5DAI A;  3GGR B;  1T6L A;  3F1W A;  3LX1 A;  3A1J B;  1VYJ A;  1DML A;  2OD8 A;  3I2M X;  2IO4 B;  5E0T A;  5B7O A;  4YHR A;  3VKX A;  1RWZ A;  1YYP A;  5E0U A;  2NTI B;  2ZVL A;  3HI8 A; 
#chains in the Genus database with same CATH topology
 2HII B;  3V62 B;  2AWA A;  3HSL X;  2Z0L A;  4L60 A;  4RJF A;  3GGR C;  3AIX B;  3G65 B;  3A1J C;  1B8H A;  1W60 A;  3P91 A;  2NTI C;  1SXJ F;  5A6D A;  2IO4 A;  1RXZ A;  3IFV A;  4ZTD A;  2HII C;  2IJX A;  5JNE D;  5CFK A;  1B77 A;  3AIZ C;  3U61 F;  2HIK B;  4D2G A;  3A2F B;  3G65 C;  3U5Z F;  3AIZ A;  3G65 A;  3TBL A;  3FDS C;  1IZ4 A;  1UD9 A;  1VYM A;  1IZ5 A;  3FDS D;  3GGR A;  5AUJ A;  2ZVW A;  3A1J A;  2HIK C;  2IX2 B;  1GE8 A;  3V61 B;  3GPN A;  2NTI A;  1U76 A;  2HIK A;  1PLR A;  2HII A;  4HK1 A;  1RXM A;  5HAC A;  3AIX A;  1AXC A;  5IXA A;  3K4X A;  2IX2 C;  2IZO B;  3LX2 A;  4TR6 A;  1UL1 A;  3GPM A;  2IX2 A;  5H0T A;  2ZVK A;  1CZD A;  2AVT A;  5IY4 A;  4L6P A;  5IWD A;  3WGW A;  5DA7 A;  1PLQ A;  3P83 A;  1ISQ A;  3P87 A;  2ZVV A;  2IZO C;  1U7B A;  3U60 F;  4CS5 A;  3V60 B;  2ZVM A;  5E0V A;  5DAI A;  3GGR B;  1T6L A;  3F1W A;  3LX1 A;  3A1J B;  1VYJ A;  1DML A;  2OD8 A;  3I2M X;  2IO4 B;  5E0T A;  5B7O A;  4YHR A;  3VKX A;  1RWZ A;  1YYP A;  5E0U A;  2NTI B;  2ZVL A;  3HI8 A; 
#chains in the Genus database with same CATH homology
 2HII B;  3V62 B;  2AWA A;  3HSL X;  2Z0L A;  4L60 A;  4RJF A;  3GGR C;  3AIX B;  3G65 B;  3A1J C;  1B8H A;  1W60 A;  3P91 A;  2NTI C;  1SXJ F;  5A6D A;  2IO4 A;  1RXZ A;  3IFV A;  4ZTD A;  2HII C;  2IJX A;  5JNE D;  5CFK A;  1B77 A;  3AIZ C;  3U61 F;  2HIK B;  4D2G A;  3A2F B;  3G65 C;  3U5Z F;  3AIZ A;  3G65 A;  3TBL A;  3FDS C;  1IZ4 A;  1UD9 A;  1VYM A;  1IZ5 A;  3FDS D;  3GGR A;  5AUJ A;  2ZVW A;  3A1J A;  2HIK C;  2IX2 B;  1GE8 A;  3V61 B;  3GPN A;  2NTI A;  1U76 A;  2HIK A;  1PLR A;  2HII A;  4HK1 A;  1RXM A;  5HAC A;  3AIX A;  1AXC A;  5IXA A;  3K4X A;  2IX2 C;  2IZO B;  3LX2 A;  4TR6 A;  1UL1 A;  3GPM A;  2IX2 A;  5H0T A;  2ZVK A;  1CZD A;  2AVT A;  5IY4 A;  4L6P A;  5IWD A;  3WGW A;  5DA7 A;  1PLQ A;  3P83 A;  1ISQ A;  3P87 A;  2ZVV A;  2IZO C;  1U7B A;  3U60 F;  4CS5 A;  3V60 B;  2ZVM A;  5E0V A;  5DAI A;  3GGR B;  1T6L A;  3F1W A;  3LX1 A;  3A1J B;  1VYJ A;  1DML A;  2OD8 A;  3I2M X;  2IO4 B;  5E0T A;  5B7O A;  4YHR A;  3VKX A;  1RWZ A;  1YYP A;  5E0U A;  2NTI B;  2ZVL A;  3HI8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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