1JENA

Human s-adenosylmethionine decarboxylase
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
261
structure length
248
Chain Sequence
SMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCPQKIEGFKRLDCQSAMFNDYNFVFTSFAKKQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of human S-adenosylmethionine decarboxylase at 2.25 A resolution reveals a novel fold.
pubmed doi rcsb
molecule tags S-adenosylmethionine decarboxylase
source organism Homo sapiens
molecule keywords PROTEIN (S-ADENOSYLMETHIONINE DECARBOXYLASE (BETA CHAIN))
total genus 66
structure length 248
sequence length 261
chains with identical sequence C
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 1999-02-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.90.10 Alpha Beta 4-Layer Sandwich S-adenosylmethionine decarboxylase S-adenosylmethionine decarboxylase 1jenA00
1JL0A 3EP9A 3H0WA 1I7CA 1JENA 3DZ6A 1TMIA 3EP7A 3EP3A 3EPBA 1I79A 1MHMA 3EP8A 1MSVA 3EP6A 1TLUA 3DZ3A 1I72A 3DZ2A 3H0VA 3EPAA 1I7MA 3DZ4A 5TVOA 1VR7A 1I7BA 3EP5A 2IIIA 3EP4A 3DZ7A 3DZ5A
chains in the Genus database with same CATH superfamily
1JL0A 3EP9A 3H0WA 1I7CA 1JENA 3DZ6A 1TMIA 3EP7A 3EP3A 3EPBA 1I79A 1MHMA 3EP8A 1MSVA 3EP6A 1TLUA 3DZ3A 1I72A 3DZ2A 3H0VA 3EPAA 1I7MA 3DZ4A 5TVOA 1VR7A 1I7BA 3EP5A 2IIIA 3EP4A 3DZ7A 3DZ5A
chains in the Genus database with same CATH topology
3DZ7B 1JL0A 3EP4B 3EP9A 3H0WA 1I7CA 1JENA 3DZ6A 1TMIA 3EP7A 3EP3A 3DZ5B 3EPBA 1I79A 1MHMA 3EP9B 3EP8A 3H0WB 1I7CB 1JENB 1MSVA 3EP6A 1TLUA 3DZ6B 3EP7B 3EP3B 3DZ3A 1MHMB 1I72A 3EPBB 1I79B 3DZ2A 3H0VA 3EP8B 3EPAA 3EP6B 1I7MA 3DZ4A 5TVOA 1VR7A 1I7BA 3DZ2B 3DZ3B 3EP5A 2IIIA 1I72B 3EP4A 3H0VB 3DZ7A 3EPAB 3EP5B 1I7MB 1I7BB 3DZ4B 3DZ5A 5TVOB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JL0 A;  3EP9 A;  3H0W A;  1I7C A;  1JEN A;  3DZ6 A;  1TMI A;  3EP7 A;  3EP3 A;  3EPB A;  1I79 A;  1MHM A;  3EP8 A;  1MSV A;  3EP6 A;  1TLU A;  3DZ3 A;  1I72 A;  3DZ2 A;  3H0V A;  3EPA A;  1I7M A;  3DZ4 A;  5TVO A;  1VR7 A;  1I7B A;  3EP5 A;  2III A;  3EP4 A;  3DZ7 A;  3DZ5 A; 
#chains in the Genus database with same CATH topology
 1JL0 A;  3EP9 A;  3H0W A;  1I7C A;  1JEN A;  3DZ6 A;  1TMI A;  3EP7 A;  3EP3 A;  3EPB A;  1I79 A;  1MHM A;  3EP8 A;  1MSV A;  3EP6 A;  1TLU A;  3DZ3 A;  1I72 A;  3DZ2 A;  3H0V A;  3EPA A;  1I7M A;  3DZ4 A;  5TVO A;  1VR7 A;  1I7B A;  3EP5 A;  2III A;  3EP4 A;  3DZ7 A;  3DZ5 A; 
#chains in the Genus database with same CATH homology
 3DZ7 B;  1JL0 A;  3EP4 B;  3EP9 A;  3H0W A;  1I7C A;  1JEN A;  3DZ6 A;  1TMI A;  3EP7 A;  3EP3 A;  3DZ5 B;  3EPB A;  1I79 A;  1MHM A;  3EP9 B;  3EP8 A;  3H0W B;  1I7C B;  1JEN B;  1MSV A;  3EP6 A;  1TLU A;  3DZ6 B;  3EP7 B;  3EP3 B;  3DZ3 A;  1MHM B;  1I72 A;  3EPB B;  1I79 B;  3DZ2 A;  3H0V A;  3EP8 B;  3EPA A;  3EP6 B;  1I7M A;  3DZ4 A;  5TVO A;  1VR7 A;  1I7B A;  3DZ2 B;  3DZ3 B;  3EP5 A;  2III A;  1I72 B;  3EP4 A;  3H0V B;  3DZ7 A;  3EPA B;  3EP5 B;  1I7M B;  1I7B B;  3DZ4 B;  3DZ5 A;  5TVO B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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