1JENB

Human s-adenosylmethionine decarboxylase
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
64
structure length
57
Chain Sequence
AHFFEGTEKLLEVWFSRGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of human S-adenosylmethionine decarboxylase at 2.25 A resolution reveals a novel fold.
pubmed doi rcsb
molecule tags S-adenosylmethionine decarboxylase
source organism Homo sapiens
molecule keywords PROTEIN (S-ADENOSYLMETHIONINE DECARBOXYLASE (BETA CHAIN))
total genus 8
structure length 57
sequence length 64
chains with identical sequence D
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 1999-02-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 1jenB01
3EP7B 3DZ7B 3EP8B 3DZ6B 3EP3B 3DZ4B 1MHMB 3EP4B 3H0VB 3H0WB 1I7BB 3EP6B 1I79B 1I7CB 3EP5B 3DZ2B 3DZ5B 5TVOB 3EPBB 3DZ3B 1I7MB 1I72B 3EP9B 1JENB 3EPAB
chains in the Genus database with same CATH superfamily
1DRUA 4WNIA 1H93A 3HJAA 3B1JA 4DIBA 2G82A 1H6BA 3E5RA 3K73O 3WGOA 1PQPA 4LGVA 3RCBA 5A06A 1P1JA 4ZICA 3LC1O 3EPBB 2D2IA 2Q22A 5GZ6A 3RC2A 1GCUA 1EBFA 2O4UX 3BTVA 4MVJH 2VYVA 2VYND 1IHYA 3PYMA 3MTJA 4IQ0A 5AVOA 2O48X 5EINA 3Q11A 4YWJA 3V2UA 3QVTA 2X5KO 1B7GO 3VOSA 2NVWA 1NBOA 3EVNA 1TVEA 1GYPA 3STHA 3C8MA 3KGDA 4H3VA 3OQBA 3GFGA 1P1FA 4MIYA 1Q7GA 3Q2KA 2GYYA 2DBVO 3DBVO 1QMHA 2I3AA 4MVJF 1YS4A 4N54A 3V5NA 4ZHSA 3E82A 3LVFO 3DOCA 2P2SA 2GLXA 3DZ3B 4MIOA 1GYQA 3EPAB 5A02A 1VM6A 1ML3A 3EP8B 1NQAO 5J9GA 2EJWA 5EERA 4MIEA 4PG5A 3B1KA 3H0VB 1JKFA 3CPSA 3FHLA 3TV1A 1PQUA 2BHLA 2G17A 3PWKA 5DDIP 3GDOA 1DC4A 1TLTA 3UUWA 4PLPA 4GQAA 1H6AA 1TA4A 2CZCA 2QZ9A 1I33A 5GZ1A 4QX6A 1RM5A 3FD8A 1GAEO 2GZ1A 2HJSA 3I23A 3DZ6B 5JYAA 3KV3O 4R3NA 1I7BB 4MJLA 2DPGA 2OZPA 4WNCA 4MINA 1ARZA 1P1IA 3IWDB 1ZNQO 2B4RO 3CEAA 1K3TA 3DAPA 3ABIA 3PWSA 3L0DA 1RM0A 4LRSB 1P9LA 1JKIA 3QV1A 1LC0A 1OBFO 1YL5A 3INGA 1CRWG 1MHMB 2R00C 4EW6A 1DC3A 4MVJM 1NWHA 4PG4A 5C7OO 4INAA 5BNTA 1I7CB 3IJPA 3L4SO 2DAPA 3MZ0A 3WBFA 1VC2A 3H9EO 4II7A 1VKOA 1YDWA 3RC1A 1SZJG 4JN6B 2POQX 3QVSA 1PU2A 1DSSG 3DMTA 2Q4EA 1VKNA 4DPLA 2BH9A 3QW2A 1EVJA 4L8VA 3GPDG 3EZYA 3IWCB 1P1HA 1P1KA 3OA0A 1S7CA 3VAZA 3EC7A 2DUUA 4MVJE 1NWCA 3DMTC 1Q2XA 4O89A 3RC9A 5EIOA 2CVOA 3QY9A 3HQ4O 3WGZA 1NPTO 4DBVO 1U8FO 3ZDFA 2X0NA 5JY6A 3PYLA 1EBUA 3PZRA 3KSDO 4XR4A 3RBVA 4PG7A 1QXSA 4XB2A 3PYXA 1GPDG 4GMFA 4GMGA 4MVJA 4HKTA 3E6AA 3GNQA 4R3WA 1DIHA 4XB1A 3K9QO 4MVJP 2VYVD 4IQ8A 3RC7A 3UW3A 4R5MA 3HXLA 3E18A 5T73A 1E7YA 2FPNA 2HKIA 3DTYA 3WYBA 2XF8A 3C1AA 4DPKA 5JW6A 1DRWA 1YWGO 1E77A 4LRTB 2H63A 3RVDA 1H94A 3DZ2B 3LC2O 4TVBA 1CF2O 1E5LA 3MOIA 3EUWA 1T4DA 3WBBA 1I72B 3CINA 2EP7A 4K9DA 1E5QA 4RL6A 1GD1O 4R51A 4L9RA 1QMIA 3QVWA 1NVMB 2Q49A 3M2TA 5A03A 2GZ3A 3DO5A 3F4LA 3L6OO 3HSKA 1J5PA 1LA2A 4PG6A 2IXBA 3BIOA 3KSZO 1BRMA 1H9BA 3KUXA 5AQ1A 1F06A 2R00A 3IWBB 2YV3A 3EP3B 3DB2A 3B20A 3DZ4B 1GADO 4FB5A 1ZH8A 5KVSA 3PZBA 1QKIA 1RM4A 2VYNA 4PG8A 4MVJG 4XQCA 1DBVO 1A7KA 3E1KA 4BOYA 3V1YA 3OA2A 3IDSA 1DC6A 1RYEA 3NT5A 3DZ7B 1MC4A 4XQ9A 1VSVA 3PFWO 3BTSA 4WOJA 4R4JA 4R54A 1DC5A 1U1IA 1I79B 4O63O 1GL3A 5C7IO 4KOAA 3WYCA 3NTQA 3OHSX 1J0XO 2AXQA 3LC7O 4DPMA 2PKQO 1RYDA 1DPGA 4P8RA 1LC3A 3PQVA 3JSAA 1NQOA 2NQTA 3H0WB 4MVJI 3EP6B 1YL6A 5EESA 3TW3A 4Z0HO 1TB4A 4GPD1 1H6CA 3CIFA 3E9MA 2PKQP 4MKXA 3EP7B 4CLQA 4YDRA 3HNPA 3TUXA 2PH5A 1I32A 3EP4B 4LSMA 1OZAA 3NTOA 4XQEA 3ZCXA 1GR0A 1E7MA 1RM3A 1FF9A 3NTRA 1MB4A 4O8JA 1PS8A 5TVOB 1NX6A 3WB9A 1I7MB 4MVJD 2EP5A 4XQGA 2GZ2A 3NT4A 3NT2A 1XEAA 4HADA 2YYYA 5A05A 5C7LO 4MKZA 4R41A 2X5JO 4O59O 5GZ3A 3K2BA 1CERA 2DC1A 2HO5A 5CEFA 3WGQA 1H6DA 2I3GA 3Q1LA 3EP5B 5KVQA 3ZJXA 3DR3A 5A04A 2B4TO 3BTUA 3DZ5B 5JYFA 3CMCO 1VSUA 2GD1O 1OFGA 3EP9B 1DRVA 1IHXA 4R5HA 1JN0A 3TZ6A 1DAPA 1PR3A 3QVXA 3TUTA 1NQ5A 1C3VA 5M6DA 3WGYA 3IP3A 4XRGA 1HDGO 1UYJA 1H2HA 1H9AA 1YL7A 1XYGA 5JYEA 3O9ZA 3U3XA 4F3YA 1T4BA 2IXAA 2I5PO 3Q0EA 3Q2IA 2PKRA 4AK1A 1JENB 4NHEA
chains in the Genus database with same CATH topology
3EP7B 3DZ4A 3DZ7B 3EP8B 3DZ6B 1MHMA 3EP4A 3EP3B 3H0VA 1MSVA 1TLUA 1I7BA 2IIIA 3H0WA 3DZ4B 1TMIA 3EP6A 1I79A 1MHMB 3EP4B 1I7CA 3EP5A 3H0VB 3H0WB 1I7BB 3DZ2A 3DZ5A 3EP6B 1I79B 3EPBA 5TVOA 1VR7A 1I7CB 1JL0A 3EP5B 1I72A 3DZ2B 3DZ3A 3DZ5B 1I7MA 3EP9A 5TVOB 3EPAA 3EPBB 1JENA 3DZ3B 3EP7A 1I7MB 1I72B 3EP9B 3DZ7A 3EP8A 3DZ6A 1JENB 3EPAB 3EP3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EP7 B;  3DZ7 B;  3EP8 B;  3DZ6 B;  3EP3 B;  3DZ4 B;  1MHM B;  3EP4 B;  3H0V B;  3H0W B;  1I7B B;  3EP6 B;  1I79 B;  1I7C B;  3EP5 B;  3DZ2 B;  3DZ5 B;  5TVO B;  3EPB B;  3DZ3 B;  1I7M B;  1I72 B;  3EP9 B;  1JEN B;  3EPA B; 
#chains in the Genus database with same CATH topology
 1DRU A;  4WNI A;  1H93 A;  3HJA A;  3B1J A;  4DIB A;  2G82 A;  1H6B A;  3E5R A;  3K73 O;  3WGO A;  1PQP A;  4LGV A;  3RCB A;  5A06 A;  1P1J A;  4ZIC A;  3LC1 O;  3EPB B;  2D2I A;  2Q22 A;  5GZ6 A;  3RC2 A;  1GCU A;  1EBF A;  2O4U X;  3BTV A;  4MVJ H;  2VYV A;  2VYN D;  1IHY A;  3PYM A;  3MTJ A;  4IQ0 A;  5AVO A;  2O48 X;  5EIN A;  3Q11 A;  4YWJ A;  3V2U A;  3QVT A;  2X5K O;  1B7G O;  3VOS A;  2NVW A;  1NBO A;  3EVN A;  1TVE A;  1GYP A;  3STH A;  3C8M A;  3KGD A;  4H3V A;  3OQB A;  3GFG A;  1P1F A;  4MIY A;  1Q7G A;  3Q2K A;  2GYY A;  2DBV O;  3DBV O;  1QMH A;  2I3A A;  4MVJ F;  1YS4 A;  4N54 A;  3V5N A;  4ZHS A;  3E82 A;  3LVF O;  3DOC A;  2P2S A;  2GLX A;  3DZ3 B;  4MIO A;  1GYQ A;  3EPA B;  5A02 A;  1VM6 A;  1ML3 A;  3EP8 B;  1NQA O;  5J9G A;  2EJW A;  5EER A;  4MIE A;  4PG5 A;  3B1K A;  3H0V B;  1JKF A;  3CPS A;  3FHL A;  3TV1 A;  1PQU A;  2BHL A;  2G17 A;  3PWK A;  5DDI P;  3GDO A;  1DC4 A;  1TLT A;  3UUW A;  4PLP A;  4GQA A;  1H6A A;  1TA4 A;  2CZC A;  2QZ9 A;  1I33 A;  5GZ1 A;  4QX6 A;  1RM5 A;  3FD8 A;  1GAE O;  2GZ1 A;  2HJS A;  3I23 A;  3DZ6 B;  5JYA A;  3KV3 O;  4R3N A;  1I7B B;  4MJL A;  2DPG A;  2OZP A;  4WNC A;  4MIN A;  1ARZ A;  1P1I A;  3IWD B;  1ZNQ O;  2B4R O;  3CEA A;  1K3T A;  3DAP A;  3ABI A;  3PWS A;  3L0D A;  1RM0 A;  4LRS B;  1P9L A;  1JKI A;  3QV1 A;  1LC0 A;  1OBF O;  1YL5 A;  3ING A;  1CRW G;  1MHM B;  2R00 C;  4EW6 A;  1DC3 A;  4MVJ M;  1NWH A;  4PG4 A;  5C7O O;  4INA A;  5BNT A;  1I7C B;  3IJP A;  3L4S O;  2DAP A;  3MZ0 A;  3WBF A;  1VC2 A;  3H9E O;  4II7 A;  1VKO A;  1YDW A;  3RC1 A;  1SZJ G;  4JN6 B;  2POQ X;  3QVS A;  1PU2 A;  1DSS G;  3DMT A;  2Q4E A;  1VKN A;  4DPL A;  2BH9 A;  3QW2 A;  1EVJ A;  4L8V A;  3GPD G;  3EZY A;  3IWC B;  1P1H A;  1P1K A;  3OA0 A;  1S7C A;  3VAZ A;  3EC7 A;  2DUU A;  4MVJ E;  1NWC A;  3DMT C;  1Q2X A;  4O89 A;  3RC9 A;  5EIO A;  2CVO A;  3QY9 A;  3HQ4 O;  3WGZ A;  1NPT O;  4DBV O;  1U8F O;  3ZDF A;  2X0N A;  5JY6 A;  3PYL A;  1EBU A;  3PZR A;  3KSD O;  4XR4 A;  3RBV A;  4PG7 A;  1QXS A;  4XB2 A;  3PYX A;  1GPD G;  4GMF A;  4GMG A;  4MVJ A;  4HKT A;  3E6A A;  3GNQ A;  4R3W A;  1DIH A;  4XB1 A;  3K9Q O;  4MVJ P;  2VYV D;  4IQ8 A;  3RC7 A;  3UW3 A;  4R5M A;  3HXL A;  3E18 A;  5T73 A;  1E7Y A;  2FPN A;  2HKI A;  3DTY A;  3WYB A;  2XF8 A;  3C1A A;  4DPK A;  5JW6 A;  1DRW A;  1YWG O;  1E77 A;  4LRT B;  2H63 A;  3RVD A;  1H94 A;  3DZ2 B;  3LC2 O;  4TVB A;  1CF2 O;  1E5L A;  3MOI A;  3EUW A;  1T4D A;  3WBB A;  1I72 B;  3CIN A;  2EP7 A;  4K9D A;  1E5Q A;  4RL6 A;  1GD1 O;  4R51 A;  4L9R A;  1QMI A;  3QVW A;  1NVM B;  2Q49 A;  3M2T A;  5A03 A;  2GZ3 A;  3DO5 A;  3F4L A;  3L6O O;  3HSK A;  1J5P A;  1LA2 A;  4PG6 A;  2IXB A;  3BIO A;  3KSZ O;  1BRM A;  1H9B A;  3KUX A;  5AQ1 A;  1F06 A;  2R00 A;  3IWB B;  2YV3 A;  3EP3 B;  3DB2 A;  3B20 A;  3DZ4 B;  1GAD O;  4FB5 A;  1ZH8 A;  5KVS A;  3PZB A;  1QKI A;  1RM4 A;  2VYN A;  4PG8 A;  4MVJ G;  4XQC A;  1DBV O;  1A7K A;  3E1K A;  4BOY A;  3V1Y A;  3OA2 A;  3IDS A;  1DC6 A;  1RYE A;  3NT5 A;  3DZ7 B;  1MC4 A;  4XQ9 A;  1VSV A;  3PFW O;  3BTS A;  4WOJ A;  4R4J A;  4R54 A;  1DC5 A;  1U1I A;  1I79 B;  4O63 O;  1GL3 A;  5C7I O;  4KOA A;  3WYC A;  3NTQ A;  3OHS X;  1J0X O;  2AXQ A;  3LC7 O;  4DPM A;  2PKQ O;  1RYD A;  1DPG A;  4P8R A;  1LC3 A;  3PQV A;  3JSA A;  1NQO A;  2NQT A;  3H0W B;  4MVJ I;  3EP6 B;  1YL6 A;  5EES A;  3TW3 A;  4Z0H O;  1TB4 A;  4GPD 1;  1H6C A;  3CIF A;  3E9M A;  2PKQ P;  4MKX A;  3EP7 B;  4CLQ A;  4YDR A;  3HNP A;  3TUX A;  2PH5 A;  1I32 A;  3EP4 B;  4LSM A;  1OZA A;  3NTO A;  4XQE A;  3ZCX A;  1GR0 A;  1E7M A;  1RM3 A;  1FF9 A;  3NTR A;  1MB4 A;  4O8J A;  1PS8 A;  5TVO B;  1NX6 A;  3WB9 A;  1I7M B;  4MVJ D;  2EP5 A;  4XQG A;  2GZ2 A;  3NT4 A;  3NT2 A;  1XEA A;  4HAD A;  2YYY A;  5A05 A;  5C7L O;  4MKZ A;  4R41 A;  2X5J O;  4O59 O;  5GZ3 A;  3K2B A;  1CER A;  2DC1 A;  2HO5 A;  5CEF A;  3WGQ A;  1H6D A;  2I3G A;  3Q1L A;  3EP5 B;  5KVQ A;  3ZJX A;  3DR3 A;  5A04 A;  2B4T O;  3BTU A;  3DZ5 B;  5JYF A;  3CMC O;  1VSU A;  2GD1 O;  1OFG A;  3EP9 B;  1DRV A;  1IHX A;  4R5H A;  1JN0 A;  3TZ6 A;  1DAP A;  1PR3 A;  3QVX A;  3TUT A;  1NQ5 A;  1C3V A;  5M6D A;  3WGY A;  3IP3 A;  4XRG A;  1HDG O;  1UYJ A;  1H2H A;  1H9A A;  1YL7 A;  1XYG A;  5JYE A;  3O9Z A;  3U3X A;  4F3Y A;  1T4B A;  2IXA A;  2I5P O;  3Q0E A;  3Q2I A;  2PKR A;  4AK1 A;  1JEN B;  4NHE A; 
#chains in the Genus database with same CATH homology
 3EP7 B;  3DZ4 A;  3DZ7 B;  3EP8 B;  3DZ6 B;  1MHM A;  3EP4 A;  3EP3 B;  3H0V A;  1MSV A;  1TLU A;  1I7B A;  2III A;  3H0W A;  3DZ4 B;  1TMI A;  3EP6 A;  1I79 A;  1MHM B;  3EP4 B;  1I7C A;  3EP5 A;  3H0V B;  3H0W B;  1I7B B;  3DZ2 A;  3DZ5 A;  3EP6 B;  1I79 B;  3EPB A;  5TVO A;  1VR7 A;  1I7C B;  1JL0 A;  3EP5 B;  1I72 A;  3DZ2 B;  3DZ3 A;  3DZ5 B;  1I7M A;  3EP9 A;  5TVO B;  3EPA A;  3EPB B;  1JEN A;  3DZ3 B;  3EP7 A;  1I7M B;  1I72 B;  3EP9 B;  3DZ7 A;  3EP8 A;  3DZ6 A;  1JEN B;  3EPA B;  3EP3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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