1JF7A

Human ptp1b catalytic domain complexed with pnu177836
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
281
structure length
281
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Synthesis and biological activity of a novel class of small molecular weight peptidomimetic competitive inhibitors of protein tyrosine phosphatase 1B.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN-TYROSINE PHOSPHATASE 1B
total genus 94
structure length 281
sequence length 281
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2001-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1jf7A00
2FJNA 4WU3A 2PA5A 1Q6TA 1KAKA 1NZ7A 2QBRA 4HJQA 1LQFA 2PBNA 1WRMA 3ZM0A 1I9SA 2R0BA 1QXKA 2ZMMA 4D3PA 1NWEA 2GWOA 2QEPA 4QUMA 1I57A 2VEWA 3OLRA 1ZCKA 3CM3A 3D44A 3ZM2A 4DGPA 3NMEA 3AWGA 4B04A 3EMUA 1ONYA 1P15A 2HNQA 1YGUA 2H03A 4GFUA 4QAHA 2HB1A 2DXPA 2G6ZA 2F6WA 1G1HA 2YDUA 5KABA 3I80A 3BM8A 5KA8A 2PI7A 2CMBA 1OETA 1NNYA 4NNDA 4R0TA 1YTNA 2HXPA 2RF6A 2CNFA 3F99A 3S3FA 2QBPA 2CMCA 2OUDA 3QCGA 1PTTA 2CM8A 5KAAA 2AZRA 4RH9A 1FPZA 2P4DA 5MMZB 2FH7A 2GJTA 4J51A 2NT7A 1XBOA 4GE2A 2H02A 3QCFA 3V0JA 2C7SA 1BZHA 3O5XA 1KAVA 2SHPA 3QCMA 3MOZA 5HDEA 2GP0A 2BZLA 2ZN7A 2PT0A 3MMJA 2CFVA 4RDDA 1EENA 3GXGA 4QBWA 1FQ1A 5KA7A 4GS0A 2CM7A 5I6VA 1NO6A 1Q6SA 4YAAA 2CNGA 1PA1A 5KA2A 3QKPA 1AAXA 2J16B 2CNIA 3EB1A 2BGEA 1U24A 4QAPA 2HC1A 2QDCA 1Q6NA 2I1YA 3U96A 3V0IA 2I6PA 3QCJA 4NYHA 3A5KA 4ZN5A 4NWGA 5K24A 2ESBA 3RGOA 3F9BA 1G7GA 4IKCA 4JNBA 1OEOX 2I6JA 2I75A 1J4XA 1GWZA 2I3UA 2I6MA 2JJDA 1C88A 3I36A 5K9VA 2QBSA 2OZ5A 2NLKA 4R30A 4ZRTA 3RZ2A 2VEXA 2B4UA 4Z6BA 2F46A 1Q6JA 2OC3A 1OEUA 5K23A 3QCBA 3OMHA 1G4WR 4WU2A 1PTUA 1OHEA 2A8BA 1G4US 1XXPA 5KADA 1L8GA 1I9TA 3ZV2A 2CMAA 2IMGA 3F81A 2E0TA 3QCNA 5KA1A 2BIJA 1C85A 2QCTA 5KA4A 3LJ8A 4OHEA 1FPRA 2QDPA 4TVVA 4D3QA 3QCHA 3SMEA 4OHLA 2C46A 3QCLA 1ONZA 4JMKA 4RKKA 2VEUA 4GE5A 1Q6PA 2M3VA 1RPMA 3QKQA 2B4SA 2QBQA 1EEOA 3F41A 3S4EA 2F6FA 2B49A 3S3EA 3D1OA 3CWEA 3BLUA 3EAXA 1YTWA 1OHDA 3EU0A 4ERCA 3ZMQA 1D5RA 3BRHA 5IBSA 1MKPA 4R0SA 4OHHA 1U26A 4OHDA 3O4SA 1A5YA 2I3RA 3V0DA 2F71A 1WAXA 2WGPA 4HJPA 2I6OA 1ECVA 5KACA 3D1HA 4H1OA 4GFVA 5GTJA 2HC2A 2H04A 3D9CA 1NL9A 4AZ1A 1YN9A 1NWLA 3D42A 2H4KA 1XM2A 4JBCA 2CM3A 2Y2FA 3B7OA 1QZ0A 1VHRA 3O4UA 5LXQB 2NT2A 2PSZA 1WCHA 4BJOA 4H34A 2P6XA 5AWXA 1ZCLA 5K25A 1G1FA 4PVGA 1V3AA 2BV5A 2NZ6A 1L8KA 2Y96A 4BPCA 4MBBA 1OEMX 3QCDA 2I42A 2I5XA 1SUGA 1YPTA 3M4UA 2CNEA 5J8RA 1BZCA 1G7FA 4S0GA 4RI4A 5BZXA 2CNHA 3QCEA 2AHSA 3GXHA 2Q47A 5KA9A 5IBMA 2B07A 1G1GA 3AWFA 4JMJA 1C83A 2F6ZA 4QUNA 1T49A 3AWEA 1ZZWA 3RGQA 2NTAA 1PH0A 2G59A 2F6TA 2F70A 3ZMPA 1XXVA 2QDMA 2I6IA 2I4EA 3PS5A 4ZI4A 3A5JA 1BZJA 3I7ZA 1PTYA 3QCIA 4HRFA 3O3LA 3V0EA 3S3KA 2BGDA 4GRYA 3ZM1A 3QCCA 2B4OA 3V0HA 4ICZA 2F6YA 3F9AA 3V0GA 1OESA 1LYVA 4I8NA 1C84A 5EHRA 2H4VA 3EZZA 4WOHA 4KYRA 4RH5A 1GFYA 2J17A 1C87A 2HVLA 3N0AA 1T4JA 2QCJA 1YGRA 1LARA 3S3HA 5KA3A 2NV5A 3H2XA 4GE6A 1R6HA 4Y2EA 4GRZA 4PYHA 1M3GA 1ZC0A 2CM2A 2HNPA 3BLTA 5BUGA 1PYNA 4D3RA 2FJMA 4RI5A 5M43A 1OEVA 4RHGA 1T48A 1JLNA 4Y14A 4KYQA 4OHIA 4YR8B 5K9WA 1YZ4A 2F6VA 4GWFA 5KA0A 2CJZA 3SR9A 1Q1MA 1C86A 2Q05A 2VEVA 1JF7A 4DGXA 1YFOA 1YWFA 1PXHA 5BZZA 2OOQA 1Q6MA 1PTVA 2J16A 4WTYA 1XRIA 2B4PA 2MBCA 4NWFA 3V0FA 2HCMA 3QCKA 1U25A 3RO1A 3O4TA 2I4GA 1RXDA 3S4OA 3MOWA 1X24A 2VEYA 1PA9A 2I4HA 2H4GA 2HY3A 4QBEA 4KI9A 2A3KA 1OHCA 1YTSA 4NX8A 2B3OA 2PQ5A 5EHPA 3ZM3A 5K22A 5BX1A 3D1QA
chains in the Genus database with same CATH superfamily
2FJNA 4WU3A 2PA5A 3LK7A 1Q6TA 1KAKA 1NZ7A 2QBRA 4HJQA 1LQFA 2PBNA 1WRMA 3ZM0A 1I9SA 2R0BA 1QXKA 2ZMMA 4D3PA 1NWEA 2GWOA 2QEPA 4QUMA 1I57A 2VEWA 3OLRA 1ZCKA 3CM3A 3D44A 3ZM2A 1GQQA 4DGPA 1E8CA 1JBVA 3NMEA 2UAGA 2XJAA 2UUOA 3AWGA 2GCBA 4B04A 3EMUA 1ONYA 1P15A 2HNQA 1YGUA 2H03A 4GFUA 4QAHA 2HB1A 2DXPA 2G6ZA 2F6WA 1G1HA 2YDUA 5KABA 3I80A 3BM8A 1JBWA 5KA8A 2PI7A 2CMBA 1OETA 1NNYA 4NNDA 2F00A 4R0TA 1YTNA 2HXPA 2RF6A 2CNFA 2GC6A 3F99A 3S3FA 2QBPA 2CMCA 2OUDA 3QCGA 1PTTA 2CM8A 5KAAA 4CVMA 2AZRA 4RH9A 3QCZA 1O5ZA 1FPZA 2P4DA 3HN7A 4UAGA 5MMZB 2FH7A 2GJTA 4J51A 2NT7A 1XBOA 4GE2A 2H02A 3QCFA 3V0JA 2C7SA 1BZHA 3O5XA 1KAVA 2SHPA 3QCMA 3MOZA 5HDEA 2GP0A 2BZLA 2ZN7A 2PT0A 2WJPA 3MMJA 4BUCA 2CFVA 4RDDA 1EENA 3GXGA 4QBWA 1FQ1A 5KA7A 4GS0A 2CM7A 5I6VA 1NO6A 1Q6SA 4YAAA 2CNGA 1PA1A 5KA2A 3QKPA 1AAXA 2J16B 2CNIA 4QDIA 3EB1A 2BGEA 1U24A 4QAPA 2HC1A 2QDCA 1Q6NA 2I1YA 3U96A 3V0IA 2I6PA 3QCJA 4NYHA 3A5KA 3UAGA 4ZN5A 4NWGA 5K24A 2ESBA 3RGOA 3F9BA 1G7GA 4IKCA 2XPCA 4JNBA 2AM2A 3MVNA 1OEOX 2I6JA 2I75A 1J4XA 1GWZA 2I3UA 2I6MA 2JJDA 1C88A 3I36A 5A5FA 5K9VA 2QBSA 2OZ5A 2NLKA 4R30A 4ZRTA 3RZ2A 2VEXA 2B4UA 4Z6BA 2F46A 1Q6JA 2OC3A 2Y68A 4C12A 1OEUA 5K23A 3QCBA 3OMHA 1G4WR 4WU2A 1PTUA 1OHEA 2A8BA 1G4US 1XXPA 4C13A 5KADA 2VORA 1L8GA 1I9TA 1FGSA 3ZV2A 2CMAA 1UAGA 2IMGA 3F81A 2E0TA 3QCNA 5KA1A 2BIJA 1C85A 2QCTA 5KA4A 3LJ8A 4OHEA 1FPRA 2QDPA 4TVVA 4D3QA 3QCHA 3SMEA 4OHLA 2C46A 3QCLA 1ONZA 4JMKA 4RKKA 2VEUA 4GE5A 1Q6PA 2X5OA 3ZM6A 2M3VA 1RPMA 3QKQA 2B4SA 2JFGA 4HV4A 2QBQA 1EEOA 2GCAA 4QF5A 3F41A 3S4EA 2F6FA 2B49A 3S3EA 3D1OA 3CWEA 3BLUA 3EAXA 2VOSA 1YTWA 1OHDA 3EU0A 4ERCA 3ZMQA 1D5RA 3BRHA 5IBSA 1MKPA 4R0SA 4OHHA 1U26A 3PYZA 4OHDA 3O4SA 1A5YA 2I3RA 3V0DA 2F71A 1WAXA 2WGPA 4HJPA 2I6OA 1ECVA 5KACA 3D1HA 4H1OA 2VTEA 4GFVA 1W7KA 5GTJA 2HC2A 2H04A 3D9CA 1NL9A 4AZ1A 1YN9A 1NWLA 3D42A 2H4KA 1XM2A 4JBCA 2CM3A 2Y2FA 3ZL8A 2UUPA 3B7OA 1QZ0A 4ZIYA 1VHRA 3O4UA 5LXQB 2NT2A 2PSZA 1P3DA 1WCHA 4BJOA 4H34A 2P6XA 5AWXA 1ZCLA 5K25A 1G1FA 4PVGA 1V3AA 2BV5A 2NZ6A 1L8KA 2Y96A 4BPCA 4MBBA 1OEMX 3QCDA 3N2AA 2I42A 2I5XA 1SUGA 1YPTA 3M4UA 2CNEA 5J8RA 1BZCA 1G7FA 4S0GA 1GQYA 4RI4A 5BZXA 2Y1OA 2CNHA 2AHSA 3QCEA 3GXHA 2Q47A 5KA9A 5IBMA 2B07A 4CVKA 1G1GA 3AWFA 4JMJA 1C83A 2F6ZA 4QUNA 1T49A 3AWEA 1ZZWA 3RGQA 2NTAA 1PH0A 2G59A 2F6TA 2F70A 3ZMPA 1XXVA 2QDMA 2I6IA 2Y66A 2I4EA 3PS5A 4ZI4A 3A5JA 1BZJA 3I7ZA 2WTZA 1PTYA 3QCIA 4HRFA 3O3LA 3V0EA 3S3KA 2BGDA 4GRYA 3ZM1A 3QCCA 2B4OA 3V0HA 4ICZA 2F6YA 3F9AA 1J6UA 3V0GA 1OESA 1LYVA 4I8NA 1C84A 5EHRA 2H4VA 3EZZA 4WOHA 4CVLA 4KYRA 4RH5A 1GFYA 2J17A 1C87A 2HVLA 3N0AA 1T4JA 2QCJA 1YGRA 1LARA 3S3HA 5KA3A 2NV5A 3H2XA 4GE6A 1R6HA 5A5EA 1P31A 4Y2EA 4GRZA 4PYHA 1M3GA 1ZC0A 2CM2A 2HNPA 3BLTA 5BUGA 1PYNA 2GC5A 4D3RA 2FJMA 4RI5A 5M43A 1OEVA 4RHGA 1T48A 1JLNA 4Y14A 1W78A 4KYQA 4OHIA 4YR8B 5K9WA 1YZ4A 2F6VA 4GWFA 5KA0A 2Y67A 2CJZA 1E0DA 3SR9A 1Q1MA 1C86A 3ZM5A 2Q05A 2VEVA 1JF7A 4DGXA 1YFOA 3NRSA 1YWFA 1PXHA 5BZZA 2OOQA 1Q6MA 1PTVA 1EEHA 2J16A 4WTYA 1GG4A 1XRIA 2B4PA 2MBCA 4NWFA 3V0FA 2HCMA 3QCKA 2JFHA 1U25A 3RO1A 3O4TA 4BUBA 2I4GA 1RXDA 3S4OA 3MOWA 1X24A 2VEYA 1PA9A 2I4HA 2H4GA 2HY3A 2VTDA 2JFFA 4QBEA 4KI9A 2A3KA 1OHCA 1YTSA 4NX8A 2B3OA 2AM1A 2PQ5A 5EHPA 3ZM3A 5K22A 5BX1A 3D1QA
chains in the Genus database with same CATH topology
2FJNA 4WU3A 2PA5A 1Q6TA 1KAKA 1NZ7A 2QBRA 4HJQA 1LQFA 2PBNA 1WRMA 3ZM0A 1I9SA 2R0BA 1QXKA 2ZMMA 4D3PA 1NWEA 2GWOA 2QEPA 4QUMA 1I57A 2VEWA 3OLRA 1ZCKA 3CM3A 3D44A 3ZM2A 4DGPA 3NMEA 3AWGA 4B04A 3EMUA 1ONYA 1P15A 2HNQA 1YGUA 2H03A 4GFUA 4QAHA 2HB1A 2DXPA 2G6ZA 2F6WA 1G1HA 2YDUA 5KABA 3I80A 3BM8A 5KA8A 2PI7A 2CMBA 1OETA 1NNYA 4NNDA 4R0TA 1YTNA 2HXPA 2RF6A 2CNFA 3F99A 3S3FA 2QBPA 2CMCA 2OUDA 3QCGA 1PTTA 2CM8A 5KAAA 2AZRA 4RH9A 1FPZA 2P4DA 5MMZB 2FH7A 2GJTA 4J51A 2NT7A 1XBOA 4GE2A 2H02A 3QCFA 3V0JA 2C7SA 1BZHA 3O5XA 1KAVA 2SHPA 3QCMA 3MOZA 5HDEA 2GP0A 2BZLA 2ZN7A 2PT0A 3MMJA 2CFVA 4RDDA 1EENA 3GXGA 4QBWA 1FQ1A 5KA7A 4GS0A 2CM7A 5I6VA 1NO6A 1Q6SA 4YAAA 2CNGA 1PA1A 5KA2A 3QKPA 1AAXA 2J16B 2CNIA 3EB1A 2BGEA 1U24A 4QAPA 2HC1A 2QDCA 1Q6NA 2I1YA 3U96A 3V0IA 2I6PA 3QCJA 4NYHA 3A5KA 4ZN5A 4NWGA 5K24A 2ESBA 3RGOA 3F9BA 1G7GA 4IKCA 4JNBA 1OEOX 2I6JA 2I75A 1J4XA 1GWZA 2I3UA 2I6MA 2JJDA 1C88A 3I36A 5K9VA 2QBSA 2OZ5A 2NLKA 4R30A 4ZRTA 3RZ2A 2VEXA 2B4UA 4Z6BA 2F46A 1Q6JA 2OC3A 1OEUA 5K23A 3QCBA 3OMHA 1G4WR 4WU2A 1PTUA 1OHEA 2A8BA 1G4US 1XXPA 5KADA 1L8GA 1I9TA 3ZV2A 2CMAA 2IMGA 3F81A 2E0TA 3QCNA 5KA1A 2BIJA 1C85A 2QCTA 5KA4A 3LJ8A 4OHEA 1FPRA 2QDPA 4TVVA 4D3QA 3QCHA 3SMEA 4OHLA 2C46A 3QCLA 1ONZA 4JMKA 4RKKA 2VEUA 4GE5A 1Q6PA 2M3VA 1RPMA 3QKQA 2B4SA 2QBQA 1EEOA 3F41A 3S4EA 2F6FA 2B49A 3S3EA 3D1OA 3CWEA 3BLUA 3EAXA 1YTWA 1OHDA 3EU0A 4ERCA 3ZMQA 1D5RA 3BRHA 5IBSA 1MKPA 4R0SA 4OHHA 1U26A 4OHDA 3O4SA 1A5YA 2I3RA 3V0DA 2F71A 1WAXA 2WGPA 4HJPA 2I6OA 1ECVA 5KACA 3D1HA 4H1OA 4GFVA 5GTJA 2HC2A 2H04A 3D9CA 1NL9A 4AZ1A 1YN9A 1NWLA 3D42A 2H4KA 1XM2A 4JBCA 2CM3A 2Y2FA 3B7OA 1QZ0A 1VHRA 3O4UA 5LXQB 2NT2A 2PSZA 1WCHA 4BJOA 4H34A 2P6XA 5AWXA 1ZCLA 5K25A 1G1FA 4PVGA 1V3AA 2BV5A 2NZ6A 1L8KA 2Y96A 4BPCA 4MBBA 1OEMX 3QCDA 2I42A 2I5XA 1SUGA 1YPTA 3M4UA 2CNEA 5J8RA 1BZCA 1G7FA 4S0GA 4RI4A 5BZXA 2CNHA 3QCEA 2AHSA 3GXHA 2Q47A 5KA9A 5IBMA 2B07A 1G1GA 3AWFA 4JMJA 1C83A 2F6ZA 4QUNA 1T49A 3AWEA 1ZZWA 3RGQA 2NTAA 1PH0A 2G59A 2F6TA 2F70A 3ZMPA 1XXVA 2QDMA 2I6IA 2I4EA 3PS5A 4ZI4A 3A5JA 1BZJA 3I7ZA 1PTYA 3QCIA 4HRFA 3O3LA 3V0EA 3S3KA 2BGDA 4GRYA 3ZM1A 3QCCA 2B4OA 3V0HA 4ICZA 2F6YA 3F9AA 3V0GA 1OESA 1LYVA 4I8NA 1C84A 5EHRA 2H4VA 3EZZA 4WOHA 4KYRA 4RH5A 1GFYA 2J17A 1C87A 2HVLA 3N0AA 1T4JA 2QCJA 1YGRA 1LARA 3S3HA 5KA3A 2NV5A 3H2XA 4GE6A 1R6HA 4Y2EA 4GRZA 4PYHA 1M3GA 1ZC0A 2CM2A 2HNPA 3BLTA 5BUGA 1PYNA 4D3RA 2FJMA 4RI5A 5M43A 1OEVA 4RHGA 1T48A 1JLNA 4Y14A 4KYQA 4OHIA 4YR8B 5K9WA 1YZ4A 2F6VA 4GWFA 5KA0A 2CJZA 3SR9A 1Q1MA 1C86A 2Q05A 2VEVA 1JF7A 4DGXA 1YFOA 1YWFA 1PXHA 5BZZA 2OOQA 1Q6MA 1PTVA 2J16A 4WTYA 1XRIA 2B4PA 2MBCA 4NWFA 3V0FA 2HCMA 3QCKA 1U25A 3RO1A 3O4TA 2I4GA 1RXDA 3S4OA 3MOWA 1X24A 2VEYA 1PA9A 2I4HA 2H4GA 2HY3A 4QBEA 4KI9A 2A3KA 1OHCA 1YTSA 4NX8A 2B3OA 2PQ5A 5EHPA 3ZM3A 5K22A 5BX1A 3D1QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FJN A;  4WU3 A;  2PA5 A;  1Q6T A;  1KAK A;  1NZ7 A;  2QBR A;  4HJQ A;  1LQF A;  2PBN A;  1WRM A;  3ZM0 A;  1I9S A;  2R0B A;  1QXK A;  2ZMM A;  4D3P A;  1NWE A;  2GWO A;  2QEP A;  4QUM A;  1I57 A;  2VEW A;  3OLR A;  1ZCK A;  3CM3 A;  3D44 A;  3ZM2 A;  4DGP A;  3NME A;  3AWG A;  4B04 A;  3EMU A;  1ONY A;  1P15 A;  2HNQ A;  1YGU A;  2H03 A;  4GFU A;  4QAH A;  2HB1 A;  2DXP A;  2G6Z A;  2F6W A;  1G1H A;  2YDU A;  5KAB A;  3I80 A;  3BM8 A;  5KA8 A;  2PI7 A;  2CMB A;  1OET A;  1NNY A;  4NND A;  4R0T A;  1YTN A;  2HXP A;  2RF6 A;  2CNF A;  3F99 A;  3S3F A;  2QBP A;  2CMC A;  2OUD A;  3QCG A;  1PTT A;  2CM8 A;  5KAA A;  2AZR A;  4RH9 A;  1FPZ A;  2P4D A;  5MMZ B;  2FH7 A;  2GJT A;  4J51 A;  2NT7 A;  1XBO A;  4GE2 A;  2H02 A;  3QCF A;  3V0J A;  2C7S A;  1BZH A;  3O5X A;  1KAV A;  2SHP A;  3QCM A;  3MOZ A;  5HDE A;  2GP0 A;  2BZL A;  2ZN7 A;  2PT0 A;  3MMJ A;  2CFV A;  4RDD A;  1EEN A;  3GXG A;  4QBW A;  1FQ1 A;  5KA7 A;  4GS0 A;  2CM7 A;  5I6V A;  1NO6 A;  1Q6S A;  4YAA A;  2CNG A;  1PA1 A;  5KA2 A;  3QKP A;  1AAX A;  2J16 B;  2CNI A;  3EB1 A;  2BGE A;  1U24 A;  4QAP A;  2HC1 A;  2QDC A;  1Q6N A;  2I1Y A;  3U96 A;  3V0I A;  2I6P A;  3QCJ A;  4NYH A;  3A5K A;  4ZN5 A;  4NWG A;  5K24 A;  2ESB A;  3RGO A;  3F9B A;  1G7G A;  4IKC A;  4JNB A;  1OEO X;  2I6J A;  2I75 A;  1J4X A;  1GWZ A;  2I3U A;  2I6M A;  2JJD A;  1C88 A;  3I36 A;  5K9V A;  2QBS A;  2OZ5 A;  2NLK A;  4R30 A;  4ZRT A;  3RZ2 A;  2VEX A;  2B4U A;  4Z6B A;  2F46 A;  1Q6J A;  2OC3 A;  1OEU A;  5K23 A;  3QCB A;  3OMH A;  1G4W R;  4WU2 A;  1PTU A;  1OHE A;  2A8B A;  1G4U S;  1XXP A;  5KAD A;  1L8G A;  1I9T A;  3ZV2 A;  2CMA A;  2IMG A;  3F81 A;  2E0T A;  3QCN A;  5KA1 A;  2BIJ A;  1C85 A;  2QCT A;  5KA4 A;  3LJ8 A;  4OHE A;  1FPR A;  2QDP A;  4TVV A;  4D3Q A;  3QCH A;  3SME A;  4OHL A;  2C46 A;  3QCL A;  1ONZ A;  4JMK A;  4RKK A;  2VEU A;  4GE5 A;  1Q6P A;  2M3V A;  1RPM A;  3QKQ A;  2B4S A;  2QBQ A;  1EEO A;  3F41 A;  3S4E A;  2F6F A;  2B49 A;  3S3E A;  3D1O A;  3CWE A;  3BLU A;  3EAX A;  1YTW A;  1OHD A;  3EU0 A;  4ERC A;  3ZMQ A;  1D5R A;  3BRH A;  5IBS A;  1MKP A;  4R0S A;  4OHH A;  1U26 A;  4OHD A;  3O4S A;  1A5Y A;  2I3R A;  3V0D A;  2F71 A;  1WAX A;  2WGP A;  4HJP A;  2I6O A;  1ECV A;  5KAC A;  3D1H A;  4H1O A;  4GFV A;  5GTJ A;  2HC2 A;  2H04 A;  3D9C A;  1NL9 A;  4AZ1 A;  1YN9 A;  1NWL A;  3D42 A;  2H4K A;  1XM2 A;  4JBC A;  2CM3 A;  2Y2F A;  3B7O A;  1QZ0 A;  1VHR A;  3O4U A;  5LXQ B;  2NT2 A;  2PSZ A;  1WCH A;  4BJO A;  4H34 A;  2P6X A;  5AWX A;  1ZCL A;  5K25 A;  1G1F A;  4PVG A;  1V3A A;  2BV5 A;  2NZ6 A;  1L8K A;  2Y96 A;  4BPC A;  4MBB A;  1OEM X;  3QCD A;  2I42 A;  2I5X A;  1SUG A;  1YPT A;  3M4U A;  2CNE A;  5J8R A;  1BZC A;  1G7F A;  4S0G A;  4RI4 A;  5BZX A;  2CNH A;  3QCE A;  2AHS A;  3GXH A;  2Q47 A;  5KA9 A;  5IBM A;  2B07 A;  1G1G A;  3AWF A;  4JMJ A;  1C83 A;  2F6Z A;  4QUN A;  1T49 A;  3AWE A;  1ZZW A;  3RGQ A;  2NTA A;  1PH0 A;  2G59 A;  2F6T A;  2F70 A;  3ZMP A;  1XXV A;  2QDM A;  2I6I A;  2I4E A;  3PS5 A;  4ZI4 A;  3A5J A;  1BZJ A;  3I7Z A;  1PTY A;  3QCI A;  4HRF A;  3O3L A;  3V0E A;  3S3K A;  2BGD A;  4GRY A;  3ZM1 A;  3QCC A;  2B4O A;  3V0H A;  4ICZ A;  2F6Y A;  3F9A A;  3V0G A;  1OES A;  1LYV A;  4I8N A;  1C84 A;  5EHR A;  2H4V A;  3EZZ A;  4WOH A;  4KYR A;  4RH5 A;  1GFY A;  2J17 A;  1C87 A;  2HVL A;  3N0A A;  1T4J A;  2QCJ A;  1YGR A;  1LAR A;  3S3H A;  5KA3 A;  2NV5 A;  3H2X A;  4GE6 A;  1R6H A;  4Y2E A;  4GRZ A;  4PYH A;  1M3G A;  1ZC0 A;  2CM2 A;  2HNP A;  3BLT A;  5BUG A;  1PYN A;  4D3R A;  2FJM A;  4RI5 A;  5M43 A;  1OEV A;  4RHG A;  1T48 A;  1JLN A;  4Y14 A;  4KYQ A;  4OHI A;  4YR8 B;  5K9W A;  1YZ4 A;  2F6V A;  4GWF A;  5KA0 A;  2CJZ A;  3SR9 A;  1Q1M A;  1C86 A;  2Q05 A;  2VEV A;  1JF7 A;  4DGX A;  1YFO A;  1YWF A;  1PXH A;  5BZZ A;  2OOQ A;  1Q6M A;  1PTV A;  2J16 A;  4WTY A;  1XRI A;  2B4P A;  2MBC A;  4NWF A;  3V0F A;  2HCM A;  3QCK A;  1U25 A;  3RO1 A;  3O4T A;  2I4G A;  1RXD A;  3S4O A;  3MOW A;  1X24 A;  2VEY A;  1PA9 A;  2I4H A;  2H4G A;  2HY3 A;  4QBE A;  4KI9 A;  2A3K A;  1OHC A;  1YTS A;  4NX8 A;  2B3O A;  2PQ5 A;  5EHP A;  3ZM3 A;  5K22 A;  5BX1 A;  3D1Q A; 
#chains in the Genus database with same CATH topology
 2FJN A;  4WU3 A;  2PA5 A;  3LK7 A;  1Q6T A;  1KAK A;  1NZ7 A;  2QBR A;  4HJQ A;  1LQF A;  2PBN A;  1WRM A;  3ZM0 A;  1I9S A;  2R0B A;  1QXK A;  2ZMM A;  4D3P A;  1NWE A;  2GWO A;  2QEP A;  4QUM A;  1I57 A;  2VEW A;  3OLR A;  1ZCK A;  3CM3 A;  3D44 A;  3ZM2 A;  1GQQ A;  4DGP A;  1E8C A;  1JBV A;  3NME A;  2UAG A;  2XJA A;  2UUO A;  3AWG A;  2GCB A;  4B04 A;  3EMU A;  1ONY A;  1P15 A;  2HNQ A;  1YGU A;  2H03 A;  4GFU A;  4QAH A;  2HB1 A;  2DXP A;  2G6Z A;  2F6W A;  1G1H A;  2YDU A;  5KAB A;  3I80 A;  3BM8 A;  1JBW A;  5KA8 A;  2PI7 A;  2CMB A;  1OET A;  1NNY A;  4NND A;  2F00 A;  4R0T A;  1YTN A;  2HXP A;  2RF6 A;  2CNF A;  2GC6 A;  3F99 A;  3S3F A;  2QBP A;  2CMC A;  2OUD A;  3QCG A;  1PTT A;  2CM8 A;  5KAA A;  4CVM A;  2AZR A;  4RH9 A;  3QCZ A;  1O5Z A;  1FPZ A;  2P4D A;  3HN7 A;  4UAG A;  5MMZ B;  2FH7 A;  2GJT A;  4J51 A;  2NT7 A;  1XBO A;  4GE2 A;  2H02 A;  3QCF A;  3V0J A;  2C7S A;  1BZH A;  3O5X A;  1KAV A;  2SHP A;  3QCM A;  3MOZ A;  5HDE A;  2GP0 A;  2BZL A;  2ZN7 A;  2PT0 A;  2WJP A;  3MMJ A;  4BUC A;  2CFV A;  4RDD A;  1EEN A;  3GXG A;  4QBW A;  1FQ1 A;  5KA7 A;  4GS0 A;  2CM7 A;  5I6V A;  1NO6 A;  1Q6S A;  4YAA A;  2CNG A;  1PA1 A;  5KA2 A;  3QKP A;  1AAX A;  2J16 B;  2CNI A;  4QDI A;  3EB1 A;  2BGE A;  1U24 A;  4QAP A;  2HC1 A;  2QDC A;  1Q6N A;  2I1Y A;  3U96 A;  3V0I A;  2I6P A;  3QCJ A;  4NYH A;  3A5K A;  3UAG A;  4ZN5 A;  4NWG A;  5K24 A;  2ESB A;  3RGO A;  3F9B A;  1G7G A;  4IKC A;  2XPC A;  4JNB A;  2AM2 A;  3MVN A;  1OEO X;  2I6J A;  2I75 A;  1J4X A;  1GWZ A;  2I3U A;  2I6M A;  2JJD A;  1C88 A;  3I36 A;  5A5F A;  5K9V A;  2QBS A;  2OZ5 A;  2NLK A;  4R30 A;  4ZRT A;  3RZ2 A;  2VEX A;  2B4U A;  4Z6B A;  2F46 A;  1Q6J A;  2OC3 A;  2Y68 A;  4C12 A;  1OEU A;  5K23 A;  3QCB A;  3OMH A;  1G4W R;  4WU2 A;  1PTU A;  1OHE A;  2A8B A;  1G4U S;  1XXP A;  4C13 A;  5KAD A;  2VOR A;  1L8G A;  1I9T A;  1FGS A;  3ZV2 A;  2CMA A;  1UAG A;  2IMG A;  3F81 A;  2E0T A;  3QCN A;  5KA1 A;  2BIJ A;  1C85 A;  2QCT A;  5KA4 A;  3LJ8 A;  4OHE A;  1FPR A;  2QDP A;  4TVV A;  4D3Q A;  3QCH A;  3SME A;  4OHL A;  2C46 A;  3QCL A;  1ONZ A;  4JMK A;  4RKK A;  2VEU A;  4GE5 A;  1Q6P A;  2X5O A;  3ZM6 A;  2M3V A;  1RPM A;  3QKQ A;  2B4S A;  2JFG A;  4HV4 A;  2QBQ A;  1EEO A;  2GCA A;  4QF5 A;  3F41 A;  3S4E A;  2F6F A;  2B49 A;  3S3E A;  3D1O A;  3CWE A;  3BLU A;  3EAX A;  2VOS A;  1YTW A;  1OHD A;  3EU0 A;  4ERC A;  3ZMQ A;  1D5R A;  3BRH A;  5IBS A;  1MKP A;  4R0S A;  4OHH A;  1U26 A;  3PYZ A;  4OHD A;  3O4S A;  1A5Y A;  2I3R A;  3V0D A;  2F71 A;  1WAX A;  2WGP A;  4HJP A;  2I6O A;  1ECV A;  5KAC A;  3D1H A;  4H1O A;  2VTE A;  4GFV A;  1W7K A;  5GTJ A;  2HC2 A;  2H04 A;  3D9C A;  1NL9 A;  4AZ1 A;  1YN9 A;  1NWL A;  3D42 A;  2H4K A;  1XM2 A;  4JBC A;  2CM3 A;  2Y2F A;  3ZL8 A;  2UUP A;  3B7O A;  1QZ0 A;  4ZIY A;  1VHR A;  3O4U A;  5LXQ B;  2NT2 A;  2PSZ A;  1P3D A;  1WCH A;  4BJO A;  4H34 A;  2P6X A;  5AWX A;  1ZCL A;  5K25 A;  1G1F A;  4PVG A;  1V3A A;  2BV5 A;  2NZ6 A;  1L8K A;  2Y96 A;  4BPC A;  4MBB A;  1OEM X;  3QCD A;  3N2A A;  2I42 A;  2I5X A;  1SUG A;  1YPT A;  3M4U A;  2CNE A;  5J8R A;  1BZC A;  1G7F A;  4S0G A;  1GQY A;  4RI4 A;  5BZX A;  2Y1O A;  2CNH A;  2AHS A;  3QCE A;  3GXH A;  2Q47 A;  5KA9 A;  5IBM A;  2B07 A;  4CVK A;  1G1G A;  3AWF A;  4JMJ A;  1C83 A;  2F6Z A;  4QUN A;  1T49 A;  3AWE A;  1ZZW A;  3RGQ A;  2NTA A;  1PH0 A;  2G59 A;  2F6T A;  2F70 A;  3ZMP A;  1XXV A;  2QDM A;  2I6I A;  2Y66 A;  2I4E A;  3PS5 A;  4ZI4 A;  3A5J A;  1BZJ A;  3I7Z A;  2WTZ A;  1PTY A;  3QCI A;  4HRF A;  3O3L A;  3V0E A;  3S3K A;  2BGD A;  4GRY A;  3ZM1 A;  3QCC A;  2B4O A;  3V0H A;  4ICZ A;  2F6Y A;  3F9A A;  1J6U A;  3V0G A;  1OES A;  1LYV A;  4I8N A;  1C84 A;  5EHR A;  2H4V A;  3EZZ A;  4WOH A;  4CVL A;  4KYR A;  4RH5 A;  1GFY A;  2J17 A;  1C87 A;  2HVL A;  3N0A A;  1T4J A;  2QCJ A;  1YGR A;  1LAR A;  3S3H A;  5KA3 A;  2NV5 A;  3H2X A;  4GE6 A;  1R6H A;  5A5E A;  1P31 A;  4Y2E A;  4GRZ A;  4PYH A;  1M3G A;  1ZC0 A;  2CM2 A;  2HNP A;  3BLT A;  5BUG A;  1PYN A;  2GC5 A;  4D3R A;  2FJM A;  4RI5 A;  5M43 A;  1OEV A;  4RHG A;  1T48 A;  1JLN A;  4Y14 A;  1W78 A;  4KYQ A;  4OHI A;  4YR8 B;  5K9W A;  1YZ4 A;  2F6V A;  4GWF A;  5KA0 A;  2Y67 A;  2CJZ A;  1E0D A;  3SR9 A;  1Q1M A;  1C86 A;  3ZM5 A;  2Q05 A;  2VEV A;  1JF7 A;  4DGX A;  1YFO A;  3NRS A;  1YWF A;  1PXH A;  5BZZ A;  2OOQ A;  1Q6M A;  1PTV A;  1EEH A;  2J16 A;  4WTY A;  1GG4 A;  1XRI A;  2B4P A;  2MBC A;  4NWF A;  3V0F A;  2HCM A;  3QCK A;  2JFH A;  1U25 A;  3RO1 A;  3O4T A;  4BUB A;  2I4G A;  1RXD A;  3S4O A;  3MOW A;  1X24 A;  2VEY A;  1PA9 A;  2I4H A;  2H4G A;  2HY3 A;  2VTD A;  2JFF A;  4QBE A;  4KI9 A;  2A3K A;  1OHC A;  1YTS A;  4NX8 A;  2B3O A;  2AM1 A;  2PQ5 A;  5EHP A;  3ZM3 A;  5K22 A;  5BX1 A;  3D1Q A; 
#chains in the Genus database with same CATH homology
 2FJN A;  4WU3 A;  2PA5 A;  1Q6T A;  1KAK A;  1NZ7 A;  2QBR A;  4HJQ A;  1LQF A;  2PBN A;  1WRM A;  3ZM0 A;  1I9S A;  2R0B A;  1QXK A;  2ZMM A;  4D3P A;  1NWE A;  2GWO A;  2QEP A;  4QUM A;  1I57 A;  2VEW A;  3OLR A;  1ZCK A;  3CM3 A;  3D44 A;  3ZM2 A;  4DGP A;  3NME A;  3AWG A;  4B04 A;  3EMU A;  1ONY A;  1P15 A;  2HNQ A;  1YGU A;  2H03 A;  4GFU A;  4QAH A;  2HB1 A;  2DXP A;  2G6Z A;  2F6W A;  1G1H A;  2YDU A;  5KAB A;  3I80 A;  3BM8 A;  5KA8 A;  2PI7 A;  2CMB A;  1OET A;  1NNY A;  4NND A;  4R0T A;  1YTN A;  2HXP A;  2RF6 A;  2CNF A;  3F99 A;  3S3F A;  2QBP A;  2CMC A;  2OUD A;  3QCG A;  1PTT A;  2CM8 A;  5KAA A;  2AZR A;  4RH9 A;  1FPZ A;  2P4D A;  5MMZ B;  2FH7 A;  2GJT A;  4J51 A;  2NT7 A;  1XBO A;  4GE2 A;  2H02 A;  3QCF A;  3V0J A;  2C7S A;  1BZH A;  3O5X A;  1KAV A;  2SHP A;  3QCM A;  3MOZ A;  5HDE A;  2GP0 A;  2BZL A;  2ZN7 A;  2PT0 A;  3MMJ A;  2CFV A;  4RDD A;  1EEN A;  3GXG A;  4QBW A;  1FQ1 A;  5KA7 A;  4GS0 A;  2CM7 A;  5I6V A;  1NO6 A;  1Q6S A;  4YAA A;  2CNG A;  1PA1 A;  5KA2 A;  3QKP A;  1AAX A;  2J16 B;  2CNI A;  3EB1 A;  2BGE A;  1U24 A;  4QAP A;  2HC1 A;  2QDC A;  1Q6N A;  2I1Y A;  3U96 A;  3V0I A;  2I6P A;  3QCJ A;  4NYH A;  3A5K A;  4ZN5 A;  4NWG A;  5K24 A;  2ESB A;  3RGO A;  3F9B A;  1G7G A;  4IKC A;  4JNB A;  1OEO X;  2I6J A;  2I75 A;  1J4X A;  1GWZ A;  2I3U A;  2I6M A;  2JJD A;  1C88 A;  3I36 A;  5K9V A;  2QBS A;  2OZ5 A;  2NLK A;  4R30 A;  4ZRT A;  3RZ2 A;  2VEX A;  2B4U A;  4Z6B A;  2F46 A;  1Q6J A;  2OC3 A;  1OEU A;  5K23 A;  3QCB A;  3OMH A;  1G4W R;  4WU2 A;  1PTU A;  1OHE A;  2A8B A;  1G4U S;  1XXP A;  5KAD A;  1L8G A;  1I9T A;  3ZV2 A;  2CMA A;  2IMG A;  3F81 A;  2E0T A;  3QCN A;  5KA1 A;  2BIJ A;  1C85 A;  2QCT A;  5KA4 A;  3LJ8 A;  4OHE A;  1FPR A;  2QDP A;  4TVV A;  4D3Q A;  3QCH A;  3SME A;  4OHL A;  2C46 A;  3QCL A;  1ONZ A;  4JMK A;  4RKK A;  2VEU A;  4GE5 A;  1Q6P A;  2M3V A;  1RPM A;  3QKQ A;  2B4S A;  2QBQ A;  1EEO A;  3F41 A;  3S4E A;  2F6F A;  2B49 A;  3S3E A;  3D1O A;  3CWE A;  3BLU A;  3EAX A;  1YTW A;  1OHD A;  3EU0 A;  4ERC A;  3ZMQ A;  1D5R A;  3BRH A;  5IBS A;  1MKP A;  4R0S A;  4OHH A;  1U26 A;  4OHD A;  3O4S A;  1A5Y A;  2I3R A;  3V0D A;  2F71 A;  1WAX A;  2WGP A;  4HJP A;  2I6O A;  1ECV A;  5KAC A;  3D1H A;  4H1O A;  4GFV A;  5GTJ A;  2HC2 A;  2H04 A;  3D9C A;  1NL9 A;  4AZ1 A;  1YN9 A;  1NWL A;  3D42 A;  2H4K A;  1XM2 A;  4JBC A;  2CM3 A;  2Y2F A;  3B7O A;  1QZ0 A;  1VHR A;  3O4U A;  5LXQ B;  2NT2 A;  2PSZ A;  1WCH A;  4BJO A;  4H34 A;  2P6X A;  5AWX A;  1ZCL A;  5K25 A;  1G1F A;  4PVG A;  1V3A A;  2BV5 A;  2NZ6 A;  1L8K A;  2Y96 A;  4BPC A;  4MBB A;  1OEM X;  3QCD A;  2I42 A;  2I5X A;  1SUG A;  1YPT A;  3M4U A;  2CNE A;  5J8R A;  1BZC A;  1G7F A;  4S0G A;  4RI4 A;  5BZX A;  2CNH A;  3QCE A;  2AHS A;  3GXH A;  2Q47 A;  5KA9 A;  5IBM A;  2B07 A;  1G1G A;  3AWF A;  4JMJ A;  1C83 A;  2F6Z A;  4QUN A;  1T49 A;  3AWE A;  1ZZW A;  3RGQ A;  2NTA A;  1PH0 A;  2G59 A;  2F6T A;  2F70 A;  3ZMP A;  1XXV A;  2QDM A;  2I6I A;  2I4E A;  3PS5 A;  4ZI4 A;  3A5J A;  1BZJ A;  3I7Z A;  1PTY A;  3QCI A;  4HRF A;  3O3L A;  3V0E A;  3S3K A;  2BGD A;  4GRY A;  3ZM1 A;  3QCC A;  2B4O A;  3V0H A;  4ICZ A;  2F6Y A;  3F9A A;  3V0G A;  1OES A;  1LYV A;  4I8N A;  1C84 A;  5EHR A;  2H4V A;  3EZZ A;  4WOH A;  4KYR A;  4RH5 A;  1GFY A;  2J17 A;  1C87 A;  2HVL A;  3N0A A;  1T4J A;  2QCJ A;  1YGR A;  1LAR A;  3S3H A;  5KA3 A;  2NV5 A;  3H2X A;  4GE6 A;  1R6H A;  4Y2E A;  4GRZ A;  4PYH A;  1M3G A;  1ZC0 A;  2CM2 A;  2HNP A;  3BLT A;  5BUG A;  1PYN A;  4D3R A;  2FJM A;  4RI5 A;  5M43 A;  1OEV A;  4RHG A;  1T48 A;  1JLN A;  4Y14 A;  4KYQ A;  4OHI A;  4YR8 B;  5K9W A;  1YZ4 A;  2F6V A;  4GWF A;  5KA0 A;  2CJZ A;  3SR9 A;  1Q1M A;  1C86 A;  2Q05 A;  2VEV A;  1JF7 A;  4DGX A;  1YFO A;  1YWF A;  1PXH A;  5BZZ A;  2OOQ A;  1Q6M A;  1PTV A;  2J16 A;  4WTY A;  1XRI A;  2B4P A;  2MBC A;  4NWF A;  3V0F A;  2HCM A;  3QCK A;  1U25 A;  3RO1 A;  3O4T A;  2I4G A;  1RXD A;  3S4O A;  3MOW A;  1X24 A;  2VEY A;  1PA9 A;  2I4H A;  2H4G A;  2HY3 A;  4QBE A;  4KI9 A;  2A3K A;  1OHC A;  1YTS A;  4NX8 A;  2B3O A;  2PQ5 A;  5EHP A;  3ZM3 A;  5K22 A;  5BX1 A;  3D1Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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